Homo sapiens

89 known processes

GFM1

G elongation factor, mitochondrial 1

(Aliases: EFG1,FLJ20773,hEFG1,GFM,EGF1,FLJ12662,FLJ13632,COXPD1,EFGM,EFG)

GFM1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of viral release from host cell GO:1902187 12 0.870
negative regulation of viral transcription GO:0032897 23 0.701
protein ubiquitination GO:0016567 314 0.576
viral transcription GO:0019083 35 0.552
viral gene expression GO:0019080 35 0.533
multi organism cellular process GO:0044764 156 0.491
negative regulation of viral process GO:0048525 66 0.453
cellular macromolecule catabolic process GO:0044265 380 0.432
cellular protein catabolic process GO:0044257 261 0.423
multi organism metabolic process GO:0044033 41 0.420
regulation of viral release from host cell GO:1902186 20 0.411
viral life cycle GO:0019058 132 0.381
protein autoubiquitination GO:0051865 37 0.370
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.369
viral process GO:0016032 146 0.350
positive regulation of autophagy GO:0010508 24 0.322
viral release from host cell GO:0019076 21 0.309
modification dependent macromolecule catabolic process GO:0043632 212 0.309
macroautophagy GO:0016236 39 0.277
ubiquitin dependent protein catabolic process GO:0006511 206 0.266
interspecies interaction between organisms GO:0044419 156 0.260
protein modification by small protein conjugation GO:0032446 342 0.257
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.253
regulation of multi organism process GO:0043900 157 0.237
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.233
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.194
regulation of cellular response to stress GO:0080135 244 0.188
modification dependent protein catabolic process GO:0019941 209 0.186
negative regulation of multi organism process GO:0043901 92 0.168
positive regulation of catabolic process GO:0009896 310 0.166
positive regulation of response to extracellular stimulus GO:0032106 14 0.158
response to ionizing radiation GO:0010212 65 0.152
regulation of response to external stimulus GO:0032101 222 0.146
positive regulation of cellular catabolic process GO:0031331 284 0.143
response to abiotic stimulus GO:0009628 336 0.139
cellular response to nutrient levels GO:0031669 69 0.137
striated muscle adaptation GO:0014888 4 0.136
positive regulation of response to external stimulus GO:0032103 88 0.120
protein catabolic process GO:0030163 325 0.116
proteasomal protein catabolic process GO:0010498 176 0.113
cellular response to starvation GO:0009267 58 0.112
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.103
defense response GO:0006952 315 0.098
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.098
autophagy GO:0006914 88 0.098
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.095
regulation of macroautophagy GO:0016241 19 0.093
regulation of autophagy GO:0010506 52 0.091
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.090
purine nucleoside triphosphate catabolic process GO:0009146 392 0.090
innate immune response GO:0045087 178 0.086
response to radiation GO:0009314 151 0.084
negative regulation of intracellular signal transduction GO:1902532 183 0.083
cellular response to extracellular stimulus GO:0031668 72 0.080
response to gamma radiation GO:0010332 14 0.079
response to nutrient levels GO:0031667 81 0.078
i kappab kinase nf kappab signaling GO:0007249 166 0.070
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.069
organophosphate catabolic process GO:0046434 430 0.065
cardiovascular system development GO:0072358 262 0.065
determination of adult lifespan GO:0008340 2 0.065
system process GO:0003008 349 0.064
cellular response to external stimulus GO:0071496 111 0.060
regulation of response to nutrient levels GO:0032107 22 0.060
mitochondrial respiratory chain complex i biogenesis GO:0097031 16 0.059
negative regulation of i kappab kinase nf kappab signaling GO:0043124 32 0.058
response to starvation GO:0042594 59 0.058
immune response GO:0006955 307 0.057
memory GO:0007613 3 0.053
ribonucleoside monophosphate catabolic process GO:0009158 158 0.053
nucleoside phosphate catabolic process GO:1901292 412 0.052
regulation of viral process GO:0050792 103 0.051
organelle assembly GO:0070925 176 0.050
nadh dehydrogenase complex assembly GO:0010257 16 0.050
response to extracellular stimulus GO:0009991 85 0.050
rna processing GO:0006396 255 0.050
post embryonic development GO:0009791 2 0.049
multicellular organismal aging GO:0010259 3 0.049
regulation of cellular amine metabolic process GO:0033238 11 0.044
ncrna metabolic process GO:0034660 108 0.044
cellular macromolecular complex assembly GO:0034622 324 0.043
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.042
cardiac muscle contraction GO:0060048 34 0.040
purine nucleoside triphosphate metabolic process GO:0009144 412 0.040
regulation of response to extracellular stimulus GO:0032104 22 0.039
purine ribonucleoside metabolic process GO:0046128 437 0.039
ribonucleoside triphosphate catabolic process GO:0009203 391 0.039
regulation of viral transcription GO:0046782 34 0.038
mitochondrial transport GO:0006839 60 0.038
mitochondrion organization GO:0007005 156 0.037
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.036
muscle contraction GO:0006936 73 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.035
cellular component morphogenesis GO:0032989 314 0.034
cytoplasmic transport GO:0016482 379 0.034
rna interference GO:0016246 4 0.032
mitochondrial respiratory chain complex assembly GO:0033108 23 0.030
purine ribonucleotide catabolic process GO:0009154 404 0.030
ribonucleotide catabolic process GO:0009261 405 0.029
nucleotide catabolic process GO:0009166 408 0.028
ribonucleoside triphosphate metabolic process GO:0009199 412 0.028
cellular protein complex assembly GO:0043623 188 0.028
cellular amino acid metabolic process GO:0006520 116 0.028
cellular component assembly involved in morphogenesis GO:0010927 73 0.027
purine nucleoside catabolic process GO:0006152 398 0.026
cardiac muscle tissue development GO:0048738 39 0.025
purine containing compound catabolic process GO:0072523 411 0.025
purine nucleoside monophosphate catabolic process GO:0009128 158 0.025
protein localization to mitochondrion GO:0070585 25 0.025
oxidation reduction process GO:0055114 396 0.025
nerve development GO:0021675 4 0.025
regulation of cellular ketone metabolic process GO:0010565 50 0.024
regulation of microtubule based process GO:0032886 74 0.024
response to organic cyclic compound GO:0014070 204 0.023
purine nucleoside monophosphate metabolic process GO:0009126 186 0.023
lipid metabolic process GO:0006629 381 0.023
regulation of cellular amino acid metabolic process GO:0006521 6 0.023
mrna metabolic process GO:0016071 175 0.023
translation GO:0006412 132 0.022
nervous system development GO:0007399 293 0.022
negative regulation of phosphorus metabolic process GO:0010563 267 0.022
negative regulation of cellular amine metabolic process GO:0033239 3 0.022
response to lipid GO:0033993 206 0.021
response to dexamethasone GO:0071548 1 0.021
trna processing GO:0008033 23 0.021
cellular response to oxygen containing compound GO:1901701 276 0.020
coenzyme metabolic process GO:0006732 65 0.020
amine metabolic process GO:0009308 44 0.020
blood circulation GO:0008015 113 0.020
negative regulation of phosphate metabolic process GO:0045936 267 0.020
negative regulation of hydrolase activity GO:0051346 182 0.020
cellular lipid metabolic process GO:0044255 303 0.020
glycosyl compound catabolic process GO:1901658 413 0.019
histone modification GO:0016570 251 0.019
mitochondrion distribution GO:0048311 3 0.019
methylation GO:0032259 106 0.018
chromatin modification GO:0016568 298 0.018
dephosphorylation GO:0016311 209 0.018
atp metabolic process GO:0046034 176 0.018
cell projection organization GO:0030030 252 0.017
macromolecule methylation GO:0043414 97 0.017
actin filament based movement GO:0030048 17 0.017
protein import GO:0017038 130 0.017
ribonucleoprotein complex biogenesis GO:0022613 116 0.017
skeletal muscle thin filament assembly GO:0030240 3 0.017
locomotory behavior GO:0007626 1 0.017
negative regulation of protein metabolic process GO:0051248 391 0.017
transmembrane transport GO:0055085 399 0.017
heart contraction GO:0060047 62 0.017
muscle system process GO:0003012 81 0.017
negative regulation of catalytic activity GO:0043086 335 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
lipid biosynthetic process GO:0008610 177 0.016
protein localization to organelle GO:0033365 280 0.016
protein deubiquitination GO:0016579 79 0.016
cell projection morphogenesis GO:0048858 129 0.016
cellular ketone metabolic process GO:0042180 80 0.016
mitochondrial rna metabolic process GO:0000959 15 0.016
response to oxygen containing compound GO:1901700 369 0.016
establishment of protein localization to mitochondrion GO:0072655 22 0.016
tissue homeostasis GO:0001894 63 0.016
atp catabolic process GO:0006200 157 0.016
segmentation GO:0035282 4 0.016
ribonucleoprotein complex subunit organization GO:0071826 81 0.015
response to cytokine GO:0034097 232 0.015
response to external biotic stimulus GO:0043207 261 0.015
multicellular organismal homeostasis GO:0048871 67 0.015
adult locomotory behavior GO:0008344 1 0.015
response to biotic stimulus GO:0009607 276 0.015
carbohydrate metabolic process GO:0005975 207 0.015
ribonucleoside catabolic process GO:0042454 406 0.015
anatomical structure homeostasis GO:0060249 100 0.015
covalent chromatin modification GO:0016569 254 0.015
neurological system process GO:0050877 163 0.015
negative regulation of cellular component organization GO:0051129 235 0.015
gene silencing GO:0016458 49 0.015
response to virus GO:0009615 126 0.014
vesicle mediated transport GO:0016192 371 0.014
anatomical structure formation involved in morphogenesis GO:0048646 284 0.014
cofactor metabolic process GO:0051186 87 0.014
cellular response to dexamethasone stimulus GO:0071549 1 0.014
growth GO:0040007 202 0.014
striated muscle tissue development GO:0014706 59 0.014
nucleoside monophosphate catabolic process GO:0009125 159 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.014
regulation of anatomical structure morphogenesis GO:0022603 286 0.014
chromatin organization GO:0006325 351 0.013
mrna processing GO:0006397 133 0.013
cation transport GO:0006812 331 0.013
protein modification by small protein removal GO:0070646 92 0.013
regulation of protein catabolic process GO:0042176 155 0.013
regulation of growth GO:0040008 165 0.013
single organism cellular localization GO:1902580 332 0.013
mitochondrial respiratory chain complex i assembly GO:0032981 16 0.013
purine nucleotide catabolic process GO:0006195 405 0.013
positive regulation of apoptotic process GO:0043065 246 0.013
sex differentiation GO:0007548 45 0.013
striated muscle contraction GO:0006941 52 0.013
neurogenesis GO:0022008 169 0.013
negative regulation of cellular protein metabolic process GO:0032269 353 0.013
nucleoside triphosphate catabolic process GO:0009143 394 0.012
mitotic sister chromatid segregation GO:0000070 53 0.012
cellular response to dna damage stimulus GO:0006974 379 0.012
positive regulation of cell death GO:0010942 263 0.012
cellular amine metabolic process GO:0044106 41 0.012
monocarboxylic acid metabolic process GO:0032787 185 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
receptor metabolic process GO:0043112 81 0.012
intracellular protein transport GO:0006886 270 0.012
intracellular protein transmembrane transport GO:0065002 24 0.012
regulation of vasculature development GO:1901342 97 0.012
cardiac muscle cell contraction GO:0086003 4 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
regulation of protein kinase activity GO:0045859 289 0.012
rrna processing GO:0006364 35 0.012
response to electrical stimulus GO:0051602 1 0.012
regulation of proteolysis GO:0030162 293 0.011
head development GO:0060322 108 0.011
regulation of dephosphorylation GO:0035303 96 0.011
protein homooligomerization GO:0051260 100 0.011
reproductive process GO:0022414 106 0.011
ncrna processing GO:0034470 83 0.011
cardiac myofibril assembly GO:0055003 3 0.011
microtubule based process GO:0007017 210 0.011
response to inorganic substance GO:0010035 127 0.011
reproductive structure development GO:0048608 55 0.011
motor neuron axon guidance GO:0008045 2 0.011
reproductive system development GO:0061458 56 0.011
organ morphogenesis GO:0009887 147 0.011
trna metabolic process GO:0006399 35 0.011
negative regulation of phosphatase activity GO:0010923 61 0.011
cell morphogenesis GO:0000902 296 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
retina homeostasis GO:0001895 42 0.011
protein acetylation GO:0006473 116 0.011
maintenance of location GO:0051235 112 0.011
nucleoside triphosphate metabolic process GO:0009141 422 0.011
cell growth GO:0016049 160 0.011
cranial nerve development GO:0021545 4 0.011
negative regulation of protein maturation GO:1903318 142 0.011
regulation of cell growth GO:0001558 135 0.011
positive regulation of gliogenesis GO:0014015 4 0.010
cellular response to oxidative stress GO:0034599 85 0.010
lipid localization GO:0010876 106 0.010
negative regulation of proteolysis GO:0045861 132 0.010
negative regulation of dephosphorylation GO:0035305 63 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.010
circulatory system development GO:0072359 262 0.010
nucleoside catabolic process GO:0009164 408 0.010

GFM1 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.176
myopathy DOID:423 104 0.051
muscular disease DOID:0080000 114 0.051
heart disease DOID:114 68 0.051
cardiomyopathy DOID:0050700 50 0.051
dilated cardiomyopathy DOID:12930 32 0.051
intrinsic cardiomyopathy DOID:0060036 50 0.051
cardiovascular system disease DOID:1287 106 0.051
muscle tissue disease DOID:66 113 0.051
muscular dystrophy DOID:9884 51 0.022
sensory system disease DOID:0050155 203 0.022
eye and adnexa disease DOID:1492 150 0.022
nervous system disease DOID:863 431 0.022
eye disease DOID:5614 149 0.022
connective tissue disease DOID:65 109 0.018
bone disease DOID:0080001 88 0.018
disease of metabolism DOID:0014667 295 0.015
cancer DOID:162 167 0.013
disease of cellular proliferation DOID:14566 174 0.013
retinal disease DOID:5679 118 0.013