Homo sapiens

28 known processes

CNOT3

CCR4-NOT transcription complex, subunit 3

(Aliases: NOT3H,NOT3,KIAA0691,LENG2)

CNOT3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of stem cell maintenance GO:2000036 4 0.876
mrna metabolic process GO:0016071 175 0.675
Yeast
mrna catabolic process GO:0006402 56 0.657
Yeast
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.636
regulation of cell cycle GO:0051726 393 0.600
cellular macromolecule catabolic process GO:0044265 380 0.573
Yeast
regulation of cytoplasmic mrna processing body assembly GO:0010603 5 0.572
post embryonic development GO:0009791 2 0.549
Worm
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.524
Yeast
cell cycle checkpoint GO:0000075 117 0.477
rna 3 end processing GO:0031123 35 0.432
Yeast
mitotic cell cycle phase transition GO:0044772 162 0.410
positive regulation of cytoplasmic mrna processing body assembly GO:0010606 4 0.385
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 10 0.376
Yeast
mitotic cell cycle GO:0000278 326 0.365
cytoplasmic mrna processing body assembly GO:0033962 10 0.362
rna catabolic process GO:0006401 71 0.321
Yeast
mrna 3 end processing GO:0031124 24 0.319
Yeast
vesicle mediated transport GO:0016192 371 0.291
positive regulation of developmental process GO:0051094 314 0.287
dna damage checkpoint GO:0000077 68 0.283
positive regulation of dna templated transcription elongation GO:0032786 18 0.281
Yeast
negative regulation of cell cycle GO:0045786 193 0.277
determination of adult lifespan GO:0008340 2 0.258
Worm
cellular response to dna damage stimulus GO:0006974 379 0.249
mitotic cell cycle checkpoint GO:0007093 68 0.248
regulation of cell differentiation GO:0045595 393 0.246
rna processing GO:0006396 255 0.242
Yeast
stem cell development GO:0048864 69 0.236
mrna processing GO:0006397 133 0.224
Yeast
negative regulation of developmental process GO:0051093 247 0.219
rna phosphodiester bond hydrolysis GO:0090501 35 0.216
posttranscriptional regulation of gene expression GO:0010608 213 0.212
negative regulation of protein metabolic process GO:0051248 391 0.210
negative regulation of cell differentiation GO:0045596 171 0.207
dna integrity checkpoint GO:0031570 71 0.203
nervous system development GO:0007399 293 0.200
regulation of cell cycle phase transition GO:1901987 126 0.200
regulation of mitotic cell cycle phase transition GO:1901990 118 0.192
regulation of cell cycle process GO:0010564 266 0.192
regulation of mitotic cell cycle GO:0007346 189 0.181
mitotic cell cycle process GO:1903047 286 0.168
translation GO:0006412 132 0.166
positive regulation of cell proliferation GO:0008284 301 0.152
regulation of mrna metabolic process GO:1903311 53 0.136
mitotic dna damage checkpoint GO:0044773 28 0.135
cellular macromolecular complex assembly GO:0034622 324 0.133
dna templated transcription elongation GO:0006354 25 0.132
Yeast
negative regulation of cell cycle phase transition GO:1901988 89 0.128
positive regulation of cellular catabolic process GO:0031331 284 0.126
regulation of response to external stimulus GO:0032101 222 0.125
negative regulation of cell cycle process GO:0010948 121 0.122
growth GO:0040007 202 0.122
Worm
positive regulation of organelle assembly GO:1902117 17 0.116
regulation of cellular component biogenesis GO:0044087 281 0.112
negative regulation of cellular protein metabolic process GO:0032269 353 0.112
regulation of cell development GO:0060284 161 0.111
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 14 0.108
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.097
positive regulation of cellular component organization GO:0051130 376 0.092
regulation of stem cell differentiation GO:2000736 56 0.087
embryo development GO:0009790 123 0.084
Mouse Worm
dna conformation change GO:0071103 113 0.084
regulation of intracellular estrogen receptor signaling pathway GO:0033146 13 0.082
cell cycle phase transition GO:0044770 173 0.081
regulation of dna templated transcription elongation GO:0032784 23 0.080
Yeast
immune response GO:0006955 307 0.079
regulation of organelle assembly GO:1902115 40 0.078
negative regulation of mitotic cell cycle GO:0045930 102 0.073
regulation of defense response GO:0031347 154 0.073
intracellular receptor signaling pathway GO:0030522 104 0.072
regulation of multi organism process GO:0043900 157 0.070
cell fate commitment GO:0045165 27 0.069
response to other organism GO:0051707 261 0.069
ribonucleoprotein complex subunit organization GO:0071826 81 0.069
single organism reproductive process GO:0044702 98 0.065
Worm
ribonucleoprotein complex biogenesis GO:0022613 116 0.065
small gtpase mediated signal transduction GO:0007264 78 0.062
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 32 0.062
nuclear transcribed mrna catabolic process GO:0000956 48 0.061
Yeast
wnt signaling pathway GO:0016055 156 0.061
lipid localization GO:0010876 106 0.060
positive regulation of cell cycle process GO:0090068 106 0.060
segmentation GO:0035282 4 0.059
stem cell maintenance GO:0019827 19 0.059
negative regulation of multicellular organismal process GO:0051241 317 0.058
blastoderm segmentation GO:0007350 2 0.057
defense response GO:0006952 315 0.057
regulation of mrna processing GO:0050684 48 0.057
multicellular organismal aging GO:0010259 3 0.057
Worm
positive regulation of locomotion GO:0040017 186 0.057
dna replication GO:0006260 116 0.056
intracellular estrogen receptor signaling pathway GO:0030520 23 0.055
positive regulation of organelle organization GO:0010638 195 0.055
regulation of growth GO:0040008 165 0.055
regulation of meiotic cell cycle GO:0051445 4 0.054
actin filament based process GO:0030029 224 0.051
cell fate determination GO:0001709 3 0.051
regulation of translation GO:0006417 89 0.051
anterior posterior axis specification embryo GO:0008595 2 0.051
positive regulation of catabolic process GO:0009896 310 0.050
anterior posterior axis specification GO:0009948 2 0.050
mitotic dna integrity checkpoint GO:0044774 30 0.050
negative regulation of translation GO:0017148 37 0.049
nucleoside phosphate catabolic process GO:1901292 412 0.049
response to oxygen containing compound GO:1901700 369 0.048
cytoplasmic transport GO:0016482 379 0.048
mapk cascade GO:0000165 288 0.047
epithelium development GO:0060429 227 0.046
endocytosis GO:0006897 159 0.046
neurogenesis GO:0022008 169 0.045
negative regulation of cell proliferation GO:0008285 228 0.045
ribonucleoprotein complex assembly GO:0022618 78 0.044
receptor mediated endocytosis GO:0006898 84 0.044
positive regulation of growth GO:0045927 58 0.044
nuclear transcribed mrna catabolic process no go decay GO:0070966 2 0.043
rab protein signal transduction GO:0032482 4 0.042
cell projection organization GO:0030030 252 0.042
tripartite regional subdivision GO:0007351 2 0.042
female gamete generation GO:0007292 2 0.042
nuclear transcribed mrna poly a tail shortening GO:0000289 8 0.040
Yeast
oogenesis GO:0048477 2 0.039
nitrogen compound transport GO:0071705 191 0.039
cell cell signaling GO:0007267 155 0.038
regulation of inflammatory response GO:0050727 46 0.037
maintenance of location GO:0051235 112 0.037
positive regulation of cellular component biogenesis GO:0044089 158 0.036
circadian behavior GO:0048512 2 0.036
bone trabecula morphogenesis GO:0061430 1 0.036
cellular response to oxygen containing compound GO:1901701 276 0.034
anion transport GO:0006820 161 0.034
negative regulation of phosphate metabolic process GO:0045936 267 0.034
reproduction GO:0000003 63 0.034
Worm
regulation of response to wounding GO:1903034 101 0.033
stem cell differentiation GO:0048863 93 0.033
positive regulation of mitotic cell cycle phase transition GO:1901992 19 0.033
organelle assembly GO:0070925 176 0.032
anatomical structure formation involved in morphogenesis GO:0048646 284 0.032
Mouse
peptidyl lysine acetylation GO:0018394 101 0.031
purine ribonucleoside catabolic process GO:0046130 398 0.031
protein dna complex subunit organization GO:0071824 80 0.031
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.031
cell development GO:0048468 328 0.031
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 13 0.031
Yeast
response to wounding GO:0009611 168 0.031
methylation GO:0032259 106 0.031
regulation of dna replication GO:0006275 68 0.030
regulation of mrna catabolic process GO:0061013 13 0.030
locomotory behavior GO:0007626 1 0.030
guanosine containing compound metabolic process GO:1901068 244 0.029
histone acetylation GO:0016573 93 0.029
nucleoside triphosphate metabolic process GO:0009141 422 0.029
sex differentiation GO:0007548 45 0.029
Worm
morphogenesis of embryonic epithelium GO:0016331 4 0.029
cellular amino acid metabolic process GO:0006520 116 0.028
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.028
regulation of small gtpase mediated signal transduction GO:0051056 156 0.028
g1 s transition of mitotic cell cycle GO:0000082 78 0.028
single organism cellular localization GO:1902580 332 0.028
neuron differentiation GO:0030182 138 0.027
protein autophosphorylation GO:0046777 123 0.027
biological adhesion GO:0022610 331 0.027
intracellular protein transport GO:0006886 270 0.027
signal transduction by phosphorylation GO:0023014 297 0.027
cellular chemical homeostasis GO:0055082 180 0.026
reproductive system development GO:0061458 56 0.026
Worm
immune effector process GO:0002252 159 0.025
regulation of cellular response to stress GO:0080135 244 0.025
negative regulation of dna metabolic process GO:0051053 57 0.025
embryo development ending in birth or egg hatching GO:0009792 34 0.025
Mouse Worm
positive regulation of cytokine production GO:0001819 167 0.025
dna repair GO:0006281 198 0.025
nucleosome organization GO:0034728 66 0.025
secretion by cell GO:0032940 226 0.025
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.024
embryonic epithelial tube formation GO:0001838 4 0.024
regulation of proteolysis GO:0030162 293 0.024
nucleoside catabolic process GO:0009164 408 0.024
neural tube formation GO:0001841 3 0.024
inflammatory response GO:0006954 79 0.024
endosomal transport GO:0016197 129 0.023
ras protein signal transduction GO:0007265 73 0.023
ribonucleoside catabolic process GO:0042454 406 0.023
response to biotic stimulus GO:0009607 276 0.023
protein ubiquitination GO:0016567 314 0.023
Yeast
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900153 8 0.023
macromolecule methylation GO:0043414 97 0.023
regulation of immune response GO:0050776 201 0.023
negative regulation of apoptotic process GO:0043066 316 0.023
neuron projection development GO:0031175 106 0.022
response to external biotic stimulus GO:0043207 261 0.022
regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900151 8 0.022
positive regulation of cell death GO:0010942 263 0.022
response to abiotic stimulus GO:0009628 336 0.022
organophosphate catabolic process GO:0046434 430 0.022
epithelial cell migration GO:0010631 119 0.021
growth hormone secretion GO:0030252 4 0.021
innate immune response GO:0045087 178 0.021
developmental growth GO:0048589 48 0.021
protein acylation GO:0043543 138 0.021
positive regulation of nucleotide catabolic process GO:0030813 185 0.021
gonad development GO:0008406 34 0.021
Worm
internal protein amino acid acetylation GO:0006475 101 0.021
positive regulation of hydrolase activity GO:0051345 331 0.021
chromatin assembly GO:0031497 61 0.021
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.020
Yeast
negative regulation of wnt signaling pathway GO:0030178 69 0.020
regulation of immune effector process GO:0002697 91 0.020
positive regulation of cell migration GO:0030335 172 0.020
cell morphogenesis GO:0000902 296 0.020
dephosphorylation GO:0016311 209 0.020
generation of neurons GO:0048699 152 0.020
regulation of meiosis GO:0040020 3 0.020
guanosine containing compound catabolic process GO:1901069 239 0.019
negative regulation of intracellular steroid hormone receptor signaling pathway GO:0033144 18 0.019
ribonucleoside triphosphate catabolic process GO:0009203 391 0.019
positive regulation of cellular amine metabolic process GO:0033240 7 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
endomembrane system organization GO:0010256 196 0.019
canonical wnt signaling pathway GO:0060070 116 0.019
neuromuscular junction development GO:0007528 3 0.019
cellular homeostasis GO:0019725 196 0.019
gtp metabolic process GO:0046039 239 0.019
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.019
i kappab kinase nf kappab signaling GO:0007249 166 0.019
positive regulation of dna metabolic process GO:0051054 73 0.019
positive regulation of apoptotic process GO:0043065 246 0.019
regulation of epithelial cell migration GO:0010632 93 0.019
positive regulation of nucleotide metabolic process GO:0045981 230 0.018
regulation of transferase activity GO:0051338 355 0.018
protein maturation GO:0051604 233 0.018
nucleotide catabolic process GO:0009166 408 0.018
purine nucleoside triphosphate catabolic process GO:0009146 392 0.018
mitotic g2 dna damage checkpoint GO:0007095 7 0.018
positive regulation of ligand dependent nuclear receptor transcription coactivator activity GO:2000327 2 0.018
covalent chromatin modification GO:0016569 254 0.018
negative regulation of intracellular estrogen receptor signaling pathway GO:0033147 7 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.018
regulation of response to dna damage stimulus GO:2001020 94 0.018
positive regulation of cell differentiation GO:0045597 211 0.018
protein targeting GO:0006605 187 0.018
vesicle organization GO:0016050 62 0.018
regulation of cytoplasmic transport GO:1903649 149 0.018
oocyte development GO:0048599 1 0.018
cellular ketone metabolic process GO:0042180 80 0.018
chromatin organization GO:0006325 351 0.017
chromatin modification GO:0016568 298 0.017
regulation of establishment of protein localization GO:0070201 242 0.017
regulation of developmental growth GO:0048638 30 0.017
response to lipid GO:0033993 206 0.017
lens development in camera type eye GO:0002088 2 0.017
purine nucleoside triphosphate metabolic process GO:0009144 412 0.017
cell cycle g2 m phase transition GO:0044839 43 0.017
negative regulation of phosphorus metabolic process GO:0010563 267 0.017
response to lipopolysaccharide GO:0032496 70 0.017
response to molecule of bacterial origin GO:0002237 82 0.016
g2 m transition of mitotic cell cycle GO:0000086 41 0.016
regulation of secretion by cell GO:1903530 177 0.016
nuclear transport GO:0051169 179 0.016
regulation of dna metabolic process GO:0051052 153 0.016
negative regulation of protein kinase activity GO:0006469 98 0.016
oocyte differentiation GO:0009994 2 0.016
mitotic g2 m transition checkpoint GO:0044818 9 0.016
regulation of wnt signaling pathway GO:0030111 123 0.016
positive regulation of cellular component movement GO:0051272 181 0.016
positive regulation of immune system process GO:0002684 283 0.016
protein dna complex assembly GO:0065004 64 0.016
regulation of ras protein signal transduction GO:0046578 155 0.015
cell adhesion GO:0007155 325 0.015
protein acetylation GO:0006473 116 0.015
regulation of purine nucleotide metabolic process GO:1900542 264 0.015
negative regulation of transport GO:0051051 176 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.015
cellular response to lipid GO:0071396 127 0.015
response to starvation GO:0042594 59 0.015
positive regulation of mrna processing GO:0050685 17 0.015
ribonucleoside triphosphate metabolic process GO:0009199 412 0.015
dna templated transcription initiation GO:0006352 35 0.015
protein oligomerization GO:0051259 173 0.015
regulation of cellular amino acid metabolic process GO:0006521 6 0.015
fibroblast apoptotic process GO:0044346 8 0.015
leukocyte activation GO:0045321 164 0.015
compound eye development GO:0048749 1 0.015
positive regulation of proteolysis GO:0045862 142 0.015
histone modification GO:0016570 251 0.015
dna packaging GO:0006323 77 0.015
reproductive process GO:0022414 106 0.015
Worm
regulation of protein localization GO:0032880 296 0.014
response to light stimulus GO:0009416 87 0.014
demethylation GO:0070988 37 0.014
positive regulation of cell cycle GO:0045787 140 0.014
rhythmic behavior GO:0007622 2 0.014
g2 dna damage checkpoint GO:0031572 26 0.014
chemical homeostasis GO:0048878 306 0.014
nuclear export GO:0051168 69 0.014
transmembrane transport GO:0055085 399 0.014
interspecies interaction between organisms GO:0044419 156 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.014
positive regulation of response to external stimulus GO:0032103 88 0.014
purine containing compound catabolic process GO:0072523 411 0.014
reproductive structure development GO:0048608 55 0.014
Worm
regulation of cellular ketone metabolic process GO:0010565 50 0.013
regulation of mapk cascade GO:0043408 262 0.013
purine nucleotide catabolic process GO:0006195 405 0.013
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.013
regulation of vesicle mediated transport GO:0060627 130 0.013
response to bacterium GO:0009617 144 0.013
trabecula morphogenesis GO:0061383 2 0.013
actin cytoskeleton organization GO:0030036 207 0.013
mrna splicing via spliceosome GO:0000398 89 0.013
myeloid leukocyte migration GO:0097529 62 0.013
secretion GO:0046903 254 0.013
regulation of dephosphorylation GO:0035303 96 0.013
axis elongation GO:0003401 4 0.013
positive regulation of mitotic cell cycle GO:0045931 60 0.013
chromatin remodeling GO:0006338 55 0.013
purine nucleoside catabolic process GO:0006152 398 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.013
chromatin assembly or disassembly GO:0006333 78 0.013
cell activation GO:0001775 213 0.013
regulation of secretion GO:0051046 194 0.013
exocytosis GO:0006887 71 0.013
embryonic placenta development GO:0001892 1 0.013
neural tube closure GO:0001843 3 0.013
central nervous system development GO:0007417 123 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.013
establishment of protein localization to organelle GO:0072594 172 0.013
epithelium migration GO:0090132 119 0.012
retrograde transport endosome to golgi GO:0042147 45 0.012
lymphocyte homeostasis GO:0002260 4 0.012
glycosyl compound catabolic process GO:1901658 413 0.012
development of primary sexual characteristics GO:0045137 35 0.012
Worm
cell activation involved in immune response GO:0002263 30 0.012
cell type specific apoptotic process GO:0097285 125 0.012
positive regulation of ras gtpase activity GO:0032320 117 0.012
purine ribonucleoside metabolic process GO:0046128 437 0.012
hyperosmotic response GO:0006972 4 0.012
immune system development GO:0002520 195 0.012
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.012
regulation of response to biotic stimulus GO:0002831 55 0.012
regulation of binding GO:0051098 111 0.012
regulation of cell motility GO:2000145 299 0.012
negative regulation of phosphorylation GO:0042326 174 0.012
spermatid differentiation GO:0048515 4 0.012
protein processing GO:0016485 226 0.012
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.012
Yeast
hemopoiesis GO:0030097 180 0.012
double strand break repair GO:0006302 101 0.012
multicellular organismal reproductive process GO:0048609 40 0.012
internal peptidyl lysine acetylation GO:0018393 97 0.012
proteasomal protein catabolic process GO:0010498 176 0.011
positive regulation of phosphorylation GO:0042327 394 0.011
cell junction organization GO:0034330 79 0.011
spermatid development GO:0007286 4 0.011
positive regulation of gtpase activity GO:0043547 166 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.011
neuron development GO:0048666 113 0.011
regulation of multicellular organism growth GO:0040014 8 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.011
head development GO:0060322 108 0.011
regulation of innate immune response GO:0045088 97 0.011
regulation of protein kinase activity GO:0045859 289 0.011
hormone secretion GO:0046879 65 0.011
chordate embryonic development GO:0043009 34 0.011
Mouse
sequestering of calcium ion GO:0051208 17 0.011
regulation of retinoic acid receptor signaling pathway GO:0048385 9 0.011
primary neural tube formation GO:0014020 3 0.011
negative regulation of protein modification process GO:0031400 200 0.011
cell division GO:0051301 168 0.011
regulation of peptide transport GO:0090087 62 0.011
cation transport GO:0006812 331 0.011
tissue migration GO:0090130 119 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
regulation of protein ubiquitination GO:0031396 95 0.011
spindle organization GO:0007051 53 0.011
leukocyte migration GO:0050900 107 0.011
rna interference GO:0016246 4 0.011
positive regulation of programmed cell death GO:0043068 249 0.011
negative regulation of catalytic activity GO:0043086 335 0.011
regulation of nervous system development GO:0051960 88 0.010
nucleoside monophosphate catabolic process GO:0009125 159 0.010
regulation of cytokine production GO:0001817 232 0.010
tube closure GO:0060606 3 0.010
protein deubiquitination GO:0016579 79 0.010
amide transport GO:0042886 76 0.010
negative regulation of programmed cell death GO:0043069 321 0.010
negative regulation of intracellular signal transduction GO:1902532 183 0.010
rna splicing GO:0008380 131 0.010
response to transforming growth factor beta GO:0071559 94 0.010
negative regulation of multi organism process GO:0043901 92 0.010
multi organism cellular process GO:0044764 156 0.010
establishment of planar polarity GO:0001736 3 0.010
positive regulation of cell motility GO:2000147 177 0.010

CNOT3 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.035
disease of cellular proliferation DOID:14566 174 0.035
immune system disease DOID:2914 155 0.019
organ system cancer DOID:0050686 164 0.016
hypersensitivity reaction disease DOID:0060056 25 0.016
urinary system disease DOID:18 40 0.014
central nervous system disease DOID:331 186 0.013
brain disease DOID:936 73 0.013
nervous system disease DOID:863 431 0.013
gastrointestinal system cancer DOID:3119 52 0.013
kidney disease DOID:557 36 0.013
musculoskeletal system disease DOID:17 223 0.011