Homo sapiens

183 known processes

CNOT1

CCR4-NOT transcription complex, subunit 1

(Aliases: CDC39,NOT1,KIAA1007,NOT1H,FLJ90644,DKFZp686O168,FLJ36492,DKFZp686E0722)

CNOT1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cytoplasmic mrna processing body assembly GO:0010603 5 0.994
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 14 0.988
nuclear transcribed mrna catabolic process exonucleolytic GO:0000291 7 0.988
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.987
rna phosphodiester bond hydrolysis GO:0090501 35 0.972
positive regulation of ligand dependent nuclear receptor transcription coactivator activity GO:2000327 2 0.970
positive regulation of dna templated transcription elongation GO:0032786 18 0.935
Yeast
mrna catabolic process GO:0006402 56 0.934
rna catabolic process GO:0006401 71 0.932
cytoplasmic mrna processing body assembly GO:0033962 10 0.902
regulation of translation GO:0006417 89 0.901
Worm
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.892
nuclear transcribed mrna catabolic process no go decay GO:0070966 2 0.891
nuclear transcribed mrna poly a tail shortening GO:0000289 8 0.848
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900153 8 0.798
regulation of stem cell maintenance GO:2000036 4 0.764
translation GO:0006412 132 0.756
Worm
regulation of dna templated transcription elongation GO:0032784 23 0.748
Yeast
positive regulation of mrna catabolic process GO:0061014 10 0.737
positive regulation of organelle assembly GO:1902117 17 0.719
post embryonic development GO:0009791 2 0.701
Worm
regulation of nuclear transcribed mrna poly a tail shortening GO:0060211 8 0.690
regulation of ligand dependent nuclear receptor transcription coactivator activity GO:2000325 3 0.659
posttranscriptional regulation of gene expression GO:0010608 213 0.658
Worm
ribonucleoprotein complex subunit organization GO:0071826 81 0.657
rna 3 end processing GO:0031123 35 0.635
mrna metabolic process GO:0016071 175 0.630
positive regulation of cytoplasmic mrna processing body assembly GO:0010606 4 0.619
mrna processing GO:0006397 133 0.611
exonucleolytic nuclear transcribed mrna catabolic process involved in deadenylation dependent decay GO:0043928 6 0.605
nuclear transcribed mrna catabolic process GO:0000956 48 0.594
vesicle mediated transport GO:0016192 371 0.546
Worm
mrna 3 end processing GO:0031124 24 0.513
mitotic cell cycle phase transition GO:0044772 162 0.506
ribonucleoprotein complex assembly GO:0022618 78 0.504
cellular macromolecule catabolic process GO:0044265 380 0.464
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 8 0.463
regulation of mitotic cell cycle GO:0007346 189 0.445
positive regulation of organelle organization GO:0010638 195 0.419
positive regulation of cellular component biogenesis GO:0044089 158 0.401
negative regulation of translation GO:0017148 37 0.401
Worm
mitotic cell cycle GO:0000278 326 0.392
Worm
cellular macromolecular complex assembly GO:0034622 324 0.383
regulation of meiotic cell cycle GO:0051445 4 0.381
dna integrity checkpoint GO:0031570 71 0.376
cell cycle phase transition GO:0044770 173 0.375
positive regulation of mrna processing GO:0050685 17 0.371
determination of adult lifespan GO:0008340 2 0.362
Worm
regulation of cell cycle GO:0051726 393 0.350
Yeast
cellular response to dna damage stimulus GO:0006974 379 0.341
positive regulation of mrna 3 end processing GO:0031442 12 0.335
regulation of mitotic cell cycle phase transition GO:1901990 118 0.333
rna processing GO:0006396 255 0.327
positive regulation of cell proliferation GO:0008284 301 0.302
regulation of cellular component biogenesis GO:0044087 281 0.299
oogenesis GO:0048477 2 0.295
cell development GO:0048468 328 0.291
organelle assembly GO:0070925 176 0.270
regulation of cell cycle phase transition GO:1901987 126 0.254
regulation of cell cycle process GO:0010564 266 0.252
negative regulation of protein metabolic process GO:0051248 391 0.229
Worm
cell cycle checkpoint GO:0000075 117 0.221
dna templated transcription elongation GO:0006354 25 0.220
Yeast
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 10 0.211
Yeast
regulation of cell cycle g1 s phase transition GO:1902806 42 0.208
endocytosis GO:0006897 159 0.204
Worm
negative regulation of cell cycle phase transition GO:1901988 89 0.203
mitotic cell cycle process GO:1903047 286 0.198
Worm
female gamete generation GO:0007292 2 0.198
negative regulation of cellular protein metabolic process GO:0032269 353 0.187
Worm
negative regulation of cell cycle process GO:0010948 121 0.177
positive regulation of cellular component organization GO:0051130 376 0.167
mitotic dna damage checkpoint GO:0044773 28 0.158
positive regulation of cellular catabolic process GO:0031331 284 0.156
negative regulation of cell differentiation GO:0045596 171 0.153
lipid localization GO:0010876 106 0.150
dna replication GO:0006260 116 0.148
ribonucleoprotein complex biogenesis GO:0022613 116 0.148
mitotic cell cycle checkpoint GO:0007093 68 0.147
dna damage checkpoint GO:0000077 68 0.142
positive regulation of meiotic cell cycle GO:0051446 2 0.141
negative regulation of cell cycle GO:0045786 193 0.140
regulation of mrna 3 end processing GO:0031440 12 0.124
positive regulation of developmental process GO:0051094 314 0.120
regulation of cell differentiation GO:0045595 393 0.118
positive regulation of cell cycle GO:0045787 140 0.115
g2 dna damage checkpoint GO:0031572 26 0.115
stem cell development GO:0048864 69 0.113
nervous system development GO:0007399 293 0.104
regulation of intracellular estrogen receptor signaling pathway GO:0033146 13 0.103
growth GO:0040007 202 0.101
Yeast
positive regulation of catabolic process GO:0009896 310 0.100
negative regulation of intracellular steroid hormone receptor signaling pathway GO:0033144 18 0.099
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.093
g1 s transition of mitotic cell cycle GO:0000082 78 0.093
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.093
Yeast
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.093
regulation of mrna catabolic process GO:0061013 13 0.090
anatomical structure formation involved in morphogenesis GO:0048646 284 0.090
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.086
mitotic dna integrity checkpoint GO:0044774 30 0.075
trophectodermal cell differentiation GO:0001829 3 0.070
single organism reproductive process GO:0044702 98 0.068
single organism cellular localization GO:1902580 332 0.066
Worm
generation of neurons GO:0048699 152 0.065
positive regulation of cell cycle process GO:0090068 106 0.064
embryo development ending in birth or egg hatching GO:0009792 34 0.063
Worm
negative regulation of dna metabolic process GO:0051053 57 0.062
neurogenesis GO:0022008 169 0.062
negative regulation of dna replication GO:0008156 29 0.059
reproductive process GO:0022414 106 0.059
Yeast
ribonucleotide catabolic process GO:0009261 405 0.059
negative regulation of mitotic cell cycle GO:0045930 102 0.058
regulation of organelle assembly GO:1902115 40 0.058
positive regulation of mrna metabolic process GO:1903313 19 0.057
reproductive structure development GO:0048608 55 0.057
fibroblast apoptotic process GO:0044346 8 0.055
regulation of dna metabolic process GO:0051052 153 0.053
intracellular receptor signaling pathway GO:0030522 104 0.052
regulation of dna replication GO:0006275 68 0.052
sex differentiation GO:0007548 45 0.050
cytoplasmic transport GO:0016482 379 0.050
blood vessel morphogenesis GO:0048514 162 0.048
negative regulation of cell proliferation GO:0008285 228 0.047
blastocyst development GO:0001824 3 0.047
regulation of intracellular transport GO:0032386 195 0.047
segmentation GO:0035282 4 0.047
reproductive system development GO:0061458 56 0.046
embryo development GO:0009790 123 0.046
Worm
negative regulation of transport GO:0051051 176 0.045
maintenance of location GO:0051235 112 0.044
cell cell signaling GO:0007267 155 0.044
gonad development GO:0008406 34 0.043
positive regulation of mitotic cell cycle GO:0045931 60 0.043
oocyte development GO:0048599 1 0.042
receptor mediated endocytosis GO:0006898 84 0.042
Worm
protein localization to organelle GO:0033365 280 0.042
regulation of growth GO:0040008 165 0.041
muscle organ development GO:0007517 56 0.041
regulation of endothelial cell differentiation GO:0045601 4 0.041
cell projection organization GO:0030030 252 0.040
protein deubiquitination GO:0016579 79 0.040
cellular amino acid metabolic process GO:0006520 116 0.040
cell cycle g1 s phase transition GO:0044843 80 0.039
muscle structure development GO:0061061 98 0.039
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.038
negative regulation of developmental process GO:0051093 247 0.037
development of primary sexual characteristics GO:0045137 35 0.037
organophosphate catabolic process GO:0046434 430 0.036
positive regulation of growth GO:0045927 58 0.036
purine ribonucleoside catabolic process GO:0046130 398 0.036
regulation of cellular amine metabolic process GO:0033238 11 0.035
cardiovascular system development GO:0072358 262 0.035
mitotic g2 dna damage checkpoint GO:0007095 7 0.034
regulation of cellular amino acid metabolic process GO:0006521 6 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
regulation of mrna metabolic process GO:1903311 53 0.033
positive regulation of fibroblast apoptotic process GO:2000271 6 0.032
cellular ketone metabolic process GO:0042180 80 0.032
small gtpase mediated signal transduction GO:0007264 78 0.032
secretion GO:0046903 254 0.031
vasculature development GO:0001944 181 0.031
protein methylation GO:0006479 74 0.031
dna replication checkpoint GO:0000076 5 0.030
intracellular protein transport GO:0006886 270 0.030
regulation of cellular ketone metabolic process GO:0010565 50 0.030
rab protein signal transduction GO:0032482 4 0.030
angiogenesis GO:0001525 147 0.030
response to nitrogen compound GO:1901698 184 0.030
intracellular mrna localization GO:0008298 1 0.029
anterior posterior axis specification GO:0009948 2 0.029
nucleotide catabolic process GO:0009166 408 0.029
protein modification by small protein conjugation GO:0032446 342 0.029
amine metabolic process GO:0009308 44 0.029
cellular protein complex assembly GO:0043623 188 0.028
positive regulation of mitotic cell cycle phase transition GO:1901992 19 0.028
neuron projection development GO:0031175 106 0.028
chromatin organization GO:0006325 351 0.027
regulation of stem cell differentiation GO:2000736 56 0.027
organelle localization GO:0051640 84 0.027
Worm
establishment of protein localization to organelle GO:0072594 172 0.027
regulation of vesicle mediated transport GO:0060627 130 0.027
purine nucleoside triphosphate metabolic process GO:0009144 412 0.027
nuclear transport GO:0051169 179 0.027
dna dependent dna replication maintenance of fidelity GO:0045005 14 0.027
nucleocytoplasmic transport GO:0006913 176 0.026
regulation of microtubule based process GO:0032886 74 0.026
regulation of dna dependent dna replication GO:0090329 19 0.026
positive regulation of cell differentiation GO:0045597 211 0.026
system process GO:0003008 349 0.025
oocyte differentiation GO:0009994 2 0.025
developmental process involved in reproduction GO:0003006 66 0.024
blastocyst formation GO:0001825 3 0.024
blood vessel development GO:0001568 172 0.024
nucleoside phosphate catabolic process GO:1901292 412 0.024
reproduction GO:0000003 63 0.023
Yeast Worm
neuron differentiation GO:0030182 138 0.023
microtubule cytoskeleton organization GO:0000226 176 0.023
Worm
cellular amine metabolic process GO:0044106 41 0.022
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 13 0.022
Yeast
gtp metabolic process GO:0046039 239 0.021
epithelium development GO:0060429 227 0.021
purine nucleotide catabolic process GO:0006195 405 0.021
response to oxygen containing compound GO:1901700 369 0.021
blastoderm segmentation GO:0007350 2 0.021
negative regulation of phosphate metabolic process GO:0045936 267 0.021
nucleoside triphosphate catabolic process GO:0009143 394 0.020
nucleoside monophosphate catabolic process GO:0009125 159 0.020
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 32 0.020
oxidation reduction process GO:0055114 396 0.019
protein modification by small protein removal GO:0070646 92 0.019
positive regulation of leukocyte activation GO:0002696 80 0.019
neuron development GO:0048666 113 0.019
regulation of cytoplasmic transport GO:1903649 149 0.019
positive regulation of developmental growth GO:0048639 16 0.019
positive regulation of protein transport GO:0051222 135 0.019
mitotic g2 m transition checkpoint GO:0044818 9 0.019
cell activation GO:0001775 213 0.019
single organism nuclear import GO:1902593 104 0.019
multicellular organismal aging GO:0010259 3 0.019
Worm
protein catabolic process GO:0030163 325 0.019
tripartite regional subdivision GO:0007351 2 0.018
dna dependent dna replication GO:0006261 44 0.018
positive regulation of multicellular organism growth GO:0040018 6 0.018
regulation of immune response GO:0050776 201 0.018
immune response GO:0006955 307 0.018
guanosine containing compound metabolic process GO:1901068 244 0.018
signal transduction by phosphorylation GO:0023014 297 0.018
developmental growth GO:0048589 48 0.018
regulation of anatomical structure morphogenesis GO:0022603 286 0.018
nucleoside triphosphate metabolic process GO:0009141 422 0.018
neurotransmitter secretion GO:0007269 4 0.018
secretion by cell GO:0032940 226 0.017
regulation of nuclear division GO:0051783 65 0.017
regulation of protein complex assembly GO:0043254 147 0.017
response to organonitrogen compound GO:0010243 156 0.017
regulation of protein transport GO:0051223 213 0.017
cellular lipid metabolic process GO:0044255 303 0.017
purine nucleoside catabolic process GO:0006152 398 0.017
response to external biotic stimulus GO:0043207 261 0.016
purine containing compound catabolic process GO:0072523 411 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
memory GO:0007613 3 0.016
positive regulation of immune system process GO:0002684 283 0.016
positive regulation of cellular amine metabolic process GO:0033240 7 0.016
organonitrogen compound biosynthetic process GO:1901566 200 0.016
protein import GO:0017038 130 0.016
negative regulation of apoptotic process GO:0043066 316 0.016
positive regulation of protein complex assembly GO:0031334 86 0.016
negative regulation of phosphorus metabolic process GO:0010563 267 0.016
compound eye development GO:0048749 1 0.015
protein maturation GO:0051604 233 0.015
protein glycosylation GO:0006486 62 0.015
response to fungus GO:0009620 4 0.015
negative regulation of synaptic transmission GO:0050805 2 0.015
meiosis i GO:0007127 4 0.015
lysosomal transport GO:0007041 33 0.015
positive regulation of transport GO:0051050 336 0.015
purine nucleoside triphosphate catabolic process GO:0009146 392 0.015
membrane organization GO:0061024 292 0.015
regulation of meiosis GO:0040020 3 0.015
regulation of vasculature development GO:1901342 97 0.015
multi organism reproductive process GO:0044703 54 0.015
Yeast
ribonucleoside catabolic process GO:0042454 406 0.015
atp metabolic process GO:0046034 176 0.015
golgi vesicle transport GO:0048193 80 0.015
negative regulation of cellular component organization GO:0051129 235 0.015
stem cell maintenance GO:0019827 19 0.014
regulation of cell development GO:0060284 161 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
protein localization to chromosome GO:0034502 30 0.014
anterior posterior axis specification embryo GO:0008595 2 0.014
covalent chromatin modification GO:0016569 254 0.014
regulation of purine nucleotide catabolic process GO:0033121 205 0.014
ribonucleoside triphosphate catabolic process GO:0009203 391 0.014
cell type specific apoptotic process GO:0097285 125 0.014
regulation of cytoskeleton organization GO:0051493 177 0.014
cardiac muscle cell contraction GO:0086003 4 0.013
cellular component disassembly GO:0022411 92 0.013
actin filament based movement GO:0030048 17 0.013
innate immune response GO:0045087 178 0.013
regulation of body fluid levels GO:0050878 99 0.013
carbohydrate derivative biosynthetic process GO:1901137 207 0.013
protein targeting to nucleus GO:0044744 104 0.013
positive regulation of lymphocyte activation GO:0051251 73 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.013
regulation of nucleoside metabolic process GO:0009118 209 0.013
cell part morphogenesis GO:0032990 137 0.013
purine nucleoside monophosphate catabolic process GO:0009128 158 0.013
positive regulation of intracellular protein transport GO:0090316 76 0.013
dephosphorylation GO:0016311 209 0.013
endothelial cell differentiation GO:0045446 26 0.013
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.013
regulation of developmental growth GO:0048638 30 0.013
lymphocyte activation GO:0046649 133 0.013
glycosyl compound catabolic process GO:1901658 413 0.013
positive regulation of rab gtpase activity GO:0032851 39 0.013
positive regulation of angiogenesis GO:0045766 51 0.013
nuclear import GO:0051170 106 0.013
lipid metabolic process GO:0006629 381 0.012
response to abiotic stimulus GO:0009628 336 0.012
guanosine containing compound catabolic process GO:1901069 239 0.012
dna repair GO:0006281 198 0.012
locomotory behavior GO:0007626 1 0.012
regulation of gtpase activity GO:0043087 180 0.012
regulation of gtp catabolic process GO:0033124 180 0.012
regulation of striated muscle tissue development GO:0016202 26 0.012
response to hormone GO:0009725 175 0.012
macromolecule methylation GO:0043414 97 0.012
gtp catabolic process GO:0006184 237 0.012
actin mediated cell contraction GO:0070252 12 0.012
cell division GO:0051301 168 0.012
positive regulation of immune response GO:0050778 159 0.012
protein processing GO:0016485 226 0.012
ras protein signal transduction GO:0007265 73 0.012
lipid storage GO:0019915 28 0.012
spermatid development GO:0007286 4 0.012
histone exchange GO:0043486 3 0.012
regulation of intracellular protein transport GO:0033157 123 0.012
neural tube formation GO:0001841 3 0.012
regulation of microtubule cytoskeleton organization GO:0070507 61 0.012
regulation of histone modification GO:0031056 47 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
associative learning GO:0008306 1 0.011
regulation of protein localization GO:0032880 296 0.011
positive regulation of intracellular transport GO:0032388 104 0.011
multicellular organism reproduction GO:0032504 42 0.011
response to other organism GO:0051707 261 0.011
regulation of nucleotide catabolic process GO:0030811 205 0.011
circulatory system development GO:0072359 262 0.011
behavior GO:0007610 112 0.011
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.011
positive regulation of nucleotide metabolic process GO:0045981 230 0.011
response to organic cyclic compound GO:0014070 204 0.011
late endosome to vacuole transport GO:0045324 2 0.011
engulfment of apoptotic cell GO:0043652 2 0.011
small molecule biosynthetic process GO:0044283 157 0.011
protein targeting GO:0006605 187 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
carbohydrate metabolic process GO:0005975 207 0.011
cellular amide metabolic process GO:0043603 69 0.011
multicellular organismal reproductive process GO:0048609 40 0.011
regulation of protein targeting GO:1903533 91 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
protein alkylation GO:0008213 74 0.011
positive regulation of cell death GO:0010942 263 0.011
spindle elongation GO:0051231 4 0.011
cellular protein catabolic process GO:0044257 261 0.010
regulation of small gtpase mediated signal transduction GO:0051056 156 0.010
single organism carbohydrate metabolic process GO:0044723 193 0.010
ribonucleoside triphosphate metabolic process GO:0009199 412 0.010
nucleoside monophosphate metabolic process GO:0009123 191 0.010
regulation of chromatin modification GO:1903308 51 0.010
regulation of multicellular organism growth GO:0040014 8 0.010
endoplasmic reticulum organization GO:0007029 20 0.010
mitotic spindle elongation GO:0000022 4 0.010
protein import into nucleus GO:0006606 104 0.010
cell morphogenesis GO:0000902 296 0.010
methylation GO:0032259 106 0.010
negative regulation of catalytic activity GO:0043086 335 0.010
purine ribonucleoside metabolic process GO:0046128 437 0.010

CNOT1 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.059
nervous system disease DOID:863 431 0.059
neurodegenerative disease DOID:1289 102 0.047
immune system disease DOID:2914 155 0.028
hematopoietic system disease DOID:74 100 0.011