Homo sapiens

65 known processes

WNK4

WNK lysine deficient protein kinase 4

(Aliases: PRKWNK4,PHA2B)

WNK4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of rubidium ion transmembrane transporter activity GO:2000686 2 0.932
Human
renal sodium ion absorption GO:0070294 2 0.898
sodium ion transport GO:0006814 61 0.889
chromosome passenger complex localization to spindle midzone GO:0035853 1 0.850
distal tubule development GO:0072017 4 0.811
kidney morphogenesis GO:0060993 19 0.776
nephron morphogenesis GO:0072028 15 0.750
protein k33 linked ubiquitination GO:1990390 1 0.741
nephron tubule morphogenesis GO:0072078 13 0.700
epithelial tube morphogenesis GO:0060562 38 0.662
renal tubule development GO:0061326 19 0.642
tube development GO:0035295 125 0.616
renal sodium ion transport GO:0003096 2 0.612
vesicle targeting rough er to cis golgi GO:0048207 2 0.610
system process GO:0003008 349 0.596
tube morphogenesis GO:0035239 95 0.593
proteasomal ubiquitin independent protein catabolic process GO:0010499 3 0.588
hypotonic response GO:0006971 2 0.545
cation transport GO:0006812 331 0.529
kidney development GO:0001822 53 0.490
rubidium ion transport GO:0035826 4 0.477
Human
renal absorption GO:0070293 6 0.450
regulation of rubidium ion transport GO:2000680 3 0.443
Human
distal tubule morphogenesis GO:0072156 3 0.441
wnt signaling pathway GO:0016055 156 0.413
Fly
organ morphogenesis GO:0009887 147 0.410
female gamete generation GO:0007292 2 0.400
nephron epithelium development GO:0072009 23 0.399
urogenital system development GO:0001655 65 0.389
copii vesicle coating GO:0048208 2 0.379
ion homeostasis GO:0050801 230 0.371
cellular hypotonic response GO:0071476 2 0.296
nephron tubule development GO:0072080 17 0.293
negative regulation of programmed cell death GO:0043069 321 0.293
Human
translational initiation GO:0006413 48 0.287
chemical homeostasis GO:0048878 306 0.281
protein k48 linked ubiquitination GO:0070936 38 0.278
protein polyubiquitination GO:0000209 110 0.277
cellular potassium ion transport GO:0071804 60 0.276
protein modification by small protein conjugation GO:0032446 342 0.270
membrane organization GO:0061024 292 0.269
Human
renal system development GO:0072001 63 0.258
protein ubiquitination GO:0016567 314 0.256
single organism cellular localization GO:1902580 332 0.240
Human
actin filament based process GO:0030029 224 0.237
negative regulation of cell death GO:0060548 345 0.234
Human
oogenesis GO:0048477 2 0.233
renal system process GO:0003014 25 0.226
ubiquitin dependent protein catabolic process GO:0006511 206 0.219
inorganic ion transmembrane transport GO:0098660 231 0.219
potassium ion transmembrane transport GO:0071805 60 0.218
cation transmembrane transport GO:0098655 238 0.211
Human
metal ion transport GO:0030001 272 0.203
single organism membrane organization GO:0044802 268 0.201
Human
regulation of ion transmembrane transport GO:0034765 132 0.188
Human
cell development GO:0048468 328 0.188
Fly
protein localization to cytoskeleton GO:0044380 11 0.187
epithelium development GO:0060429 227 0.179
proteasomal protein catabolic process GO:0010498 176 0.173
regulation of cell cycle GO:0051726 393 0.171
negative regulation of protein metabolic process GO:0051248 391 0.164
protein localization to organelle GO:0033365 280 0.158
transmembrane transport GO:0055085 399 0.155
protein monoubiquitination GO:0006513 39 0.152
endosomal transport GO:0016197 129 0.139
regulation of transmembrane transporter activity GO:0022898 74 0.133
Human
peripheral nervous system development GO:0007422 2 0.131
anatomical structure formation involved in morphogenesis GO:0048646 284 0.131
establishment of vesicle localization GO:0051650 23 0.128
vesicle organization GO:0016050 62 0.124
signal transduction by phosphorylation GO:0023014 297 0.122
Human
actin cytoskeleton organization GO:0030036 207 0.122
vesicle mediated transport GO:0016192 371 0.121
Human
regulation of potassium ion transmembrane transport GO:1901379 20 0.121
modification dependent protein catabolic process GO:0019941 209 0.120
regulation of transmembrane transport GO:0034762 139 0.114
Human
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.113
tissue morphogenesis GO:0048729 96 0.110
membrane budding GO:0006900 28 0.109
negative regulation of cellular protein metabolic process GO:0032269 353 0.104
regulation of cellular ketone metabolic process GO:0010565 50 0.104
regulation of cell cycle process GO:0010564 266 0.103
potassium ion transport GO:0006813 62 0.103
inorganic cation transmembrane transport GO:0098662 194 0.099
Human
peptidyl threonine modification GO:0018210 45 0.099
Human
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.098
cytokinesis GO:0000910 96 0.097
regulation of transporter activity GO:0032409 82 0.097
Human
cellular ketone metabolic process GO:0042180 80 0.093
er to golgi vesicle mediated transport GO:0006888 19 0.091
Human
regulation of translation GO:0006417 89 0.089
cell projection organization GO:0030030 252 0.086
Fly
translation GO:0006412 132 0.085
single organism membrane budding GO:1902591 10 0.082
negative regulation of transport GO:0051051 176 0.081
Mouse
epithelial cell differentiation GO:0030855 141 0.081
cellular macromolecule catabolic process GO:0044265 380 0.081
vesicle targeting to from or within golgi GO:0048199 6 0.079
protein catabolic process GO:0030163 325 0.079
regulation of potassium ion transmembrane transporter activity GO:1901016 16 0.079
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.078
regulation of cytokinesis GO:0032465 45 0.078
regulation of cellular amino acid metabolic process GO:0006521 6 0.077
cellular protein catabolic process GO:0044257 261 0.076
amine metabolic process GO:0009308 44 0.076
regulation of cell division GO:0051302 116 0.074
response to abiotic stimulus GO:0009628 336 0.074
positive regulation of phosphorylation GO:0042327 394 0.073
Human
regulation of cellular amine metabolic process GO:0033238 11 0.072
post embryonic development GO:0009791 2 0.069
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.069
positive regulation of cellular component organization GO:0051130 376 0.067
Human
nervous system development GO:0007399 293 0.065
Fly
cell division GO:0051301 168 0.065
regulation of membrane potential GO:0042391 95 0.061
neuronal action potential GO:0019228 9 0.061
post golgi vesicle mediated transport GO:0006892 36 0.059
small gtpase mediated signal transduction GO:0007264 78 0.059
regulation of cellular component movement GO:0051270 334 0.059
ion transmembrane transport GO:0034220 338 0.058
organelle localization GO:0051640 84 0.056
modification dependent macromolecule catabolic process GO:0043632 212 0.056
cellular amino acid metabolic process GO:0006520 116 0.056
posttranscriptional regulation of gene expression GO:0010608 213 0.056
action potential GO:0001508 34 0.056
transmission of nerve impulse GO:0019226 11 0.053
cellular response to endogenous stimulus GO:0071495 336 0.051
morphogenesis of an epithelium GO:0002009 60 0.051
neuron differentiation GO:0030182 138 0.049
Fly
peptidyl serine modification GO:0018209 106 0.049
peptidyl serine phosphorylation GO:0018105 101 0.049
localization within membrane GO:0051668 14 0.048
regulation of metal ion transport GO:0010959 120 0.048
Human
vesicle targeting GO:0006903 7 0.048
regulation of translational initiation GO:0006446 24 0.046
neurological system process GO:0050877 163 0.046
cellular component morphogenesis GO:0032989 314 0.046
Fly
cell adhesion GO:0007155 325 0.045
negative regulation of ion transmembrane transport GO:0034766 26 0.045
negative regulation of ion transport GO:0043271 39 0.044
negative regulation of multicellular organismal process GO:0051241 317 0.044
Mouse
cellular amine metabolic process GO:0044106 41 0.044
enzyme linked receptor protein signaling pathway GO:0007167 303 0.043
purine nucleotide catabolic process GO:0006195 405 0.043
ribonucleoside triphosphate catabolic process GO:0009203 391 0.043
reproductive process GO:0022414 106 0.042
Worm
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.041
segmentation GO:0035282 4 0.041
neurogenesis GO:0022008 169 0.041
Fly
ras protein signal transduction GO:0007265 73 0.040
purine nucleoside triphosphate metabolic process GO:0009144 412 0.040
nucleoside catabolic process GO:0009164 408 0.040
negative regulation of transporter activity GO:0032410 25 0.039
positive regulation of developmental process GO:0051094 314 0.039
positive regulation of hydrolase activity GO:0051345 331 0.038
defense response GO:0006952 315 0.037
glycosyl compound catabolic process GO:1901658 413 0.037
lipid metabolic process GO:0006629 381 0.037
negative regulation of phosphate metabolic process GO:0045936 267 0.037
Human
regulation of protein localization GO:0032880 296 0.036
Human
mapk cascade GO:0000165 288 0.036
Human
secretion GO:0046903 254 0.036
Mouse
cellular response to abiotic stimulus GO:0071214 117 0.036
regulation of transferase activity GO:0051338 355 0.036
positive regulation of cellular amine metabolic process GO:0033240 7 0.036
response to oxidative stress GO:0006979 121 0.035
positive regulation of transferase activity GO:0051347 227 0.035
negative regulation of cellular component organization GO:0051129 235 0.035
negative regulation of translation GO:0017148 37 0.035
multicellular organismal aging GO:0010259 3 0.035
immune response GO:0006955 307 0.035
guanosine containing compound metabolic process GO:1901068 244 0.034
protein complex localization GO:0031503 31 0.034
positive regulation of catabolic process GO:0009896 310 0.034
nucleoside triphosphate metabolic process GO:0009141 422 0.034
monovalent inorganic cation transport GO:0015672 128 0.034
nucleotide catabolic process GO:0009166 408 0.034
positive regulation of apoptotic process GO:0043065 246 0.033
positive regulation of protein phosphorylation GO:0001934 313 0.032
Human
regulation of gtp catabolic process GO:0033124 180 0.032
cellular protein complex localization GO:0034629 8 0.032
locomotory behavior GO:0007626 1 0.031
multicellular organismal signaling GO:0035637 34 0.031
negative regulation of catalytic activity GO:0043086 335 0.031
Human
regulation of nucleotide metabolic process GO:0006140 269 0.031
negative regulation of cell proliferation GO:0008285 228 0.031
Human
cellular lipid metabolic process GO:0044255 303 0.030
regulation of cell migration GO:0030334 289 0.030
positive regulation of cell differentiation GO:0045597 211 0.030
negative regulation of developmental process GO:0051093 247 0.030
regulation of protein kinase activity GO:0045859 289 0.029
biological adhesion GO:0022610 331 0.029
epithelial cell development GO:0002064 34 0.029
regulation of establishment of protein localization GO:0070201 242 0.029
Human
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.029
determination of adult lifespan GO:0008340 2 0.029
positive regulation of cellular catabolic process GO:0031331 284 0.029
regulation of cellular response to stress GO:0080135 244 0.029
purine ribonucleoside catabolic process GO:0046130 398 0.028
regulation of gtpase activity GO:0043087 180 0.028
purine nucleoside catabolic process GO:0006152 398 0.028
cellular response to dna damage stimulus GO:0006974 379 0.028
negative regulation of potassium ion transmembrane transport GO:1901380 5 0.028
anterior posterior axis specification GO:0009948 2 0.028
negative regulation of apoptotic process GO:0043066 316 0.028
Human
regulation of purine nucleotide catabolic process GO:0033121 205 0.028
growth GO:0040007 202 0.027
cellular response to oxygen containing compound GO:1901701 276 0.027
hindbrain development GO:0030902 3 0.027
vesicle localization GO:0051648 26 0.027
regulation of potassium ion transport GO:0043266 24 0.027
gtp metabolic process GO:0046039 239 0.027
regulation of proteolysis GO:0030162 293 0.027
single organism reproductive process GO:0044702 98 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.027
positive regulation of kinase activity GO:0033674 204 0.026
lipid biosynthetic process GO:0008610 177 0.026
developmental process involved in reproduction GO:0003006 66 0.026
regulation of ras protein signal transduction GO:0046578 155 0.026
negative regulation of intracellular signal transduction GO:1902532 183 0.026
Human
regulation of locomotion GO:0040012 329 0.026
rho protein signal transduction GO:0007266 26 0.026
nerve development GO:0021675 4 0.025
regulation of cellular component biogenesis GO:0044087 281 0.025
positive regulation of cell proliferation GO:0008284 301 0.025
memory GO:0007613 3 0.025
morphogenesis of embryonic epithelium GO:0016331 4 0.025
regulation of cell motility GO:2000145 299 0.025
apoptotic signaling pathway GO:0097190 268 0.025
secretion by cell GO:0032940 226 0.025
response to oxygen containing compound GO:1901700 369 0.025
regulation of cell differentiation GO:0045595 393 0.024
generation of neurons GO:0048699 152 0.024
Fly
cell fate determination GO:0001709 3 0.024
positive regulation of cell death GO:0010942 263 0.024
regulation of purine nucleotide metabolic process GO:1900542 264 0.024
regeneration GO:0031099 4 0.023
blastoderm segmentation GO:0007350 2 0.023
mitotic cell cycle GO:0000278 326 0.023
intracellular protein transport GO:0006886 270 0.023
organonitrogen compound biosynthetic process GO:1901566 200 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.023
neuroblast proliferation GO:0007405 4 0.023
cell growth GO:0016049 160 0.023
regulation of protein serine threonine kinase activity GO:0071900 179 0.023
positive regulation of nucleotide metabolic process GO:0045981 230 0.023
ribonucleoside triphosphate metabolic process GO:0009199 412 0.023
ribonucleotide catabolic process GO:0009261 405 0.023
regulation of ras gtpase activity GO:0032318 128 0.023
regulation of hormone levels GO:0010817 125 0.022
purine containing compound catabolic process GO:0072523 411 0.022
positive regulation of nucleotide catabolic process GO:0030813 185 0.022
positive regulation of programmed cell death GO:0043068 249 0.022
nucleoside triphosphate catabolic process GO:0009143 394 0.022
anterior posterior axis specification embryo GO:0008595 2 0.022
embryonic epithelial tube formation GO:0001838 4 0.022
neuromuscular junction development GO:0007528 3 0.022
purine nucleoside triphosphate catabolic process GO:0009146 392 0.022
nucleoside phosphate catabolic process GO:1901292 412 0.022
organophosphate catabolic process GO:0046434 430 0.022
response to other organism GO:0051707 261 0.022
protein targeting GO:0006605 187 0.021
copii coated vesicle budding GO:0090114 5 0.021
response to biotic stimulus GO:0009607 276 0.021
purine ribonucleoside metabolic process GO:0046128 437 0.021
regulation of apoptotic signaling pathway GO:2001233 175 0.021
response to hormone GO:0009725 175 0.021
positive regulation of ion transport GO:0043270 87 0.021
Human
regulation of anatomical structure morphogenesis GO:0022603 286 0.021
regulation of endopeptidase activity GO:0052548 170 0.021
cellular homeostasis GO:0019725 196 0.021
cell morphogenesis GO:0000902 296 0.021
Fly
circulatory system development GO:0072359 262 0.021
positive regulation of cell migration GO:0030335 172 0.021
regulation of cell growth GO:0001558 135 0.020
regulation of wnt signaling pathway GO:0030111 123 0.020
Fly
tripartite regional subdivision GO:0007351 2 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.020
positive regulation of cellular component movement GO:0051272 181 0.020
positive regulation of immune system process GO:0002684 283 0.020
positive regulation of protein kinase activity GO:0045860 190 0.020
dephosphorylation GO:0016311 209 0.020
Human
inner ear morphogenesis GO:0042472 4 0.020
blood vessel development GO:0001568 172 0.020
nitrogen compound transport GO:0071705 191 0.020
positive regulation of mapk cascade GO:0043410 190 0.020
cardiovascular system development GO:0072358 262 0.020
protein autophosphorylation GO:0046777 123 0.020
Human Fly
stem cell division GO:0017145 2 0.020
oocyte differentiation GO:0009994 2 0.020
ribonucleoside catabolic process GO:0042454 406 0.019
regulation of nucleoside metabolic process GO:0009118 209 0.019
positive regulation of gtp catabolic process GO:0033126 166 0.019
cellular macromolecular complex assembly GO:0034622 324 0.019
reactive nitrogen species metabolic process GO:2001057 3 0.019
negative regulation of transmembrane transport GO:0034763 29 0.019
single organism cell adhesion GO:0098602 179 0.019
regulation of cell morphogenesis GO:0022604 153 0.019
negative regulation of cell cycle GO:0045786 193 0.019
adult locomotory behavior GO:0008344 1 0.019
negative regulation of ion transmembrane transporter activity GO:0032413 19 0.019
oocyte development GO:0048599 1 0.019
response to wounding GO:0009611 168 0.019
organic hydroxy compound metabolic process GO:1901615 147 0.019
regulation of peptidase activity GO:0052547 180 0.019
multicellular organismal reproductive process GO:0048609 40 0.019
Worm
regulation of kinase activity GO:0043549 314 0.019
protein processing GO:0016485 226 0.019
cation homeostasis GO:0055080 189 0.019
regulation of cell adhesion GO:0030155 166 0.019
limbic system development GO:0021761 3 0.018
response to lipid GO:0033993 206 0.018
positive regulation of transport GO:0051050 336 0.018
Human
guanosine containing compound catabolic process GO:1901069 239 0.018
regulation of nucleotide catabolic process GO:0030811 205 0.018
peptidyl tyrosine phosphorylation GO:0018108 170 0.018
microtubule based process GO:0007017 210 0.018
negative regulation of cell differentiation GO:0045596 171 0.018
gtp catabolic process GO:0006184 237 0.018
cell part morphogenesis GO:0032990 137 0.018
Fly
purine ribonucleotide catabolic process GO:0009154 404 0.018
endothelium development GO:0003158 33 0.018
vasculature development GO:0001944 181 0.018
negative regulation of cellular component movement GO:0051271 106 0.018
endomembrane system organization GO:0010256 196 0.018
Human
forelimb morphogenesis GO:0035136 4 0.018
metal ion homeostasis GO:0055065 169 0.018
innate immune response GO:0045087 178 0.018
establishment of protein localization to organelle GO:0072594 172 0.018
regulation of dna metabolic process GO:0051052 153 0.017
behavior GO:0007610 112 0.017
Worm
positive regulation of nucleoside metabolic process GO:0045979 186 0.017
regulation of response to external stimulus GO:0032101 222 0.017
organophosphate biosynthetic process GO:0090407 163 0.017
reactive oxygen species biosynthetic process GO:1903409 4 0.017
endothelial cell differentiation GO:0045446 26 0.017
positive regulation of organelle organization GO:0010638 195 0.017
negative regulation of protein modification process GO:0031400 200 0.017
maintenance of location GO:0051235 112 0.017
nuclear transport GO:0051169 179 0.017
epithelial cell proliferation GO:0050673 128 0.017
negative regulation of phosphorylation GO:0042326 174 0.017
Human
regulation of immune response GO:0050776 201 0.017
associative learning GO:0008306 1 0.017
regulation of epithelial cell proliferation GO:0050678 113 0.017
canonical wnt signaling pathway GO:0060070 116 0.017
Fly
thymus development GO:0048538 3 0.016
multi organism reproductive process GO:0044703 54 0.016
Worm
mitotic cell cycle process GO:1903047 286 0.016
cell cell signaling GO:0007267 155 0.016
carbohydrate metabolic process GO:0005975 207 0.016
spermatid differentiation GO:0048515 4 0.016
neuron projection development GO:0031175 106 0.016
Fly
regulation of neural precursor cell proliferation GO:2000177 4 0.016
regulation of defense response GO:0031347 154 0.016
neural crest cell development GO:0014032 3 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.016
cytokine production GO:0001816 247 0.016
small molecule biosynthetic process GO:0044283 157 0.016
peptidyl tyrosine modification GO:0018212 170 0.016
compound eye development GO:0048749 1 0.016
response to growth factor GO:0070848 205 0.016
reactive oxygen species metabolic process GO:0072593 75 0.016
reproduction GO:0000003 63 0.016
Worm
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.016
cell morphogenesis involved in differentiation GO:0000904 144 0.016
Fly
regulation of cytokine production GO:0001817 232 0.016
single organism carbohydrate metabolic process GO:0044723 193 0.016
response to external biotic stimulus GO:0043207 261 0.016
hemopoiesis GO:0030097 180 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.016
immune system development GO:0002520 195 0.016
response to organic cyclic compound GO:0014070 204 0.016
regulation of secretion GO:0051046 194 0.016
Mouse
positive regulation of cell motility GO:2000147 177 0.016
negative regulation of hydrolase activity GO:0051346 182 0.016
Human
cdc42 protein signal transduction GO:0032488 4 0.015
negative regulation of growth GO:0045926 97 0.015
cardiac muscle cell contraction GO:0086003 4 0.015
positive regulation of locomotion GO:0040017 186 0.015
negative regulation of cellular amine metabolic process GO:0033239 3 0.015
organ formation GO:0048645 3 0.015
motor neuron axon guidance GO:0008045 2 0.015
protein localization to nucleus GO:0034504 136 0.015
cellular chemical homeostasis GO:0055082 180 0.015
regulation of small gtpase mediated signal transduction GO:0051056 156 0.015
organic acid biosynthetic process GO:0016053 97 0.015
regulation of cell development GO:0060284 161 0.015
endodermal cell fate commitment GO:0001711 4 0.015
positive regulation of cell cycle GO:0045787 140 0.015
chemotaxis GO:0006935 157 0.015
Fly
actin mediated cell contraction GO:0070252 12 0.015
neural tube formation GO:0001841 3 0.015
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.015
regulation of protein transport GO:0051223 213 0.015
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.015
negative regulation of protein phosphorylation GO:0001933 140 0.015
single organismal cell cell adhesion GO:0016337 148 0.015
negative regulation of organelle organization GO:0010639 126 0.015
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
Human
central nervous system development GO:0007417 123 0.015
mating GO:0007618 1 0.015
photoreceptor cell differentiation GO:0046530 2 0.015
cellular component disassembly GO:0022411 92 0.015
positive regulation of proteolysis GO:0045862 142 0.015
regulation of epithelial cell migration GO:0010632 93 0.015
regulation of reactive oxygen species metabolic process GO:2000377 41 0.015
regulation of cytoskeleton organization GO:0051493 177 0.014
cellular metal ion homeostasis GO:0006875 146 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.014
negative regulation of apoptotic signaling pathway GO:2001234 97 0.014
establishment of protein localization to membrane GO:0090150 121 0.014
Human
regulation of mitotic cell cycle GO:0007346 189 0.014
regulation of secretion by cell GO:1903530 177 0.014
carbohydrate derivative biosynthetic process GO:1901137 207 0.014
forebrain generation of neurons GO:0021872 3 0.014
stem cell differentiation GO:0048863 93 0.014
cellular protein complex assembly GO:0043623 188 0.014
sex determination GO:0007530 3 0.014
somatic stem cell division GO:0048103 1 0.014
tissue regeneration GO:0042246 3 0.014
cell cycle phase transition GO:0044770 173 0.014
cell projection assembly GO:0030031 126 0.014
cellular response to hormone stimulus GO:0032870 125 0.014
endothelial cell development GO:0001885 18 0.014
regulation of protein maturation GO:1903317 150 0.014
regulation of intracellular transport GO:0032386 195 0.014
carboxylic acid biosynthetic process GO:0046394 97 0.014
regulation of protein catabolic process GO:0042176 155 0.014
glial cell migration GO:0008347 4 0.014
head development GO:0060322 108 0.014
activation of protein kinase activity GO:0032147 90 0.014
blood vessel morphogenesis GO:0048514 162 0.014
cell substrate adhesion GO:0031589 132 0.014
ameboidal type cell migration GO:0001667 135 0.014
organelle assembly GO:0070925 176 0.014
intrinsic apoptotic signaling pathway GO:0097193 127 0.014
positive regulation of cellular component biogenesis GO:0044089 158 0.014
morphogenesis of a polarized epithelium GO:0001738 3 0.014
negative regulation of locomotion GO:0040013 118 0.014
nucleocytoplasmic transport GO:0006913 176 0.013
neuron development GO:0048666 113 0.013
Fly
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
glycoprotein metabolic process GO:0009100 110 0.013
regulation of rho protein signal transduction GO:0035023 79 0.013
embryonic forelimb morphogenesis GO:0035115 4 0.013
cellular cation homeostasis GO:0030003 163 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.013
positive regulation of protein transport GO:0051222 135 0.013
somatic stem cell maintenance GO:0035019 4 0.013
monocarboxylic acid metabolic process GO:0032787 185 0.013
actin filament organization GO:0007015 128 0.013
negative regulation of cell adhesion GO:0007162 64 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.013
negative regulation of protein processing GO:0010955 142 0.013
hindlimb morphogenesis GO:0035137 2 0.013
regulation of mapk cascade GO:0043408 262 0.013
Human
multicellular organismal response to stress GO:0033555 1 0.013
positive regulation of synaptic transmission GO:0050806 4 0.013
protein oligomerization GO:0051259 173 0.013
cerebellum development GO:0021549 2 0.013
endocytosis GO:0006897 159 0.013
steroid metabolic process GO:0008202 94 0.013
organic anion transport GO:0015711 103 0.013
cellular response to cytokine stimulus GO:0071345 181 0.013
regulation of cysteine type endopeptidase activity GO:2000116 127 0.013
response to fungus GO:0009620 4 0.013
regulation of body fluid levels GO:0050878 99 0.013
Mouse
somitogenesis GO:0001756 2 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
prostate gland development GO:0030850 3 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.013
protein maturation GO:0051604 233 0.013
tissue migration GO:0090130 119 0.013
actin filament based movement GO:0030048 17 0.013
regulation of cell substrate adhesion GO:0010810 68 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.013
immune effector process GO:0002252 159 0.013
regulation of protein complex assembly GO:0043254 147 0.013

WNK4 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.034
disease of metabolism DOID:0014667 295 0.030
inherited metabolic disorder DOID:655 242 0.024
connective tissue disease DOID:65 109 0.023
cancer DOID:162 167 0.022
disease of cellular proliferation DOID:14566 174 0.022
organ system cancer DOID:0050686 164 0.022
sensory system disease DOID:0050155 203 0.021
nervous system disease DOID:863 431 0.021
Human
bone disease DOID:0080001 88 0.020
central nervous system disease DOID:331 186 0.018
eye and adnexa disease DOID:1492 150 0.015
eye disease DOID:5614 149 0.014
bone development disease DOID:0080006 55 0.013