|
|
leukocyte activation
|
GO:0045321 |
164 |
1.000
|
Mouse |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.998
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.997
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.995
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
21 |
0.995
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.992
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.992
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.991
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.990
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.990
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.988
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
4 |
0.988
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.983
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.983
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.979
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.979
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.975
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.971
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.970
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.969
|
|
|
|
positive regulation of alpha beta t cell proliferation
|
GO:0046641 |
5 |
0.968
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.961
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.960
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.959
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.959
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.957
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.955
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.945
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.943
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.941
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.940
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.936
|
|
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.932
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.927
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.924
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.913
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.913
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.902
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.896
|
Mouse |
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.893
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.881
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.880
|
|
|
|
granulocyte migration
|
GO:0097530 |
40 |
0.869
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.868
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.865
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.864
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.863
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.862
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.859
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.857
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.853
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.853
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.848
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.840
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.839
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.834
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.833
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.832
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.830
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.825
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.825
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.816
|
|
|
|
mast cell degranulation
|
GO:0043303 |
4 |
0.813
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.811
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.809
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.796
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.789
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
30 |
0.782
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.782
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.777
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.769
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.761
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.757
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.756
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.735
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
38 |
0.730
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.728
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
4 |
0.717
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.715
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.703
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.695
|
Mouse |
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.694
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.684
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.684
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.681
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
30 |
0.672
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.670
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.669
|
|
|
|
platelet activation
|
GO:0030168 |
44 |
0.648
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.640
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
42 |
0.639
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.631
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.628
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.625
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.621
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.620
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.616
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.609
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.595
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
17 |
0.588
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.586
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.582
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
20 |
0.572
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.542
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.539
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.537
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.536
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.528
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.526
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
19 |
0.525
|
|
|
|
activation of phospholipase c activity
|
GO:0007202 |
7 |
0.523
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.519
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.511
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.504
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.496
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.493
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.491
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.488
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.479
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.477
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.476
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.476
|
|
|
|
negative regulation of leukocyte activation
|
GO:0002695 |
26 |
0.470
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.468
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.445
|
|
|
|
phagocytosis recognition
|
GO:0006910 |
3 |
0.442
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
18 |
0.428
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.425
|
Mouse |
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.425
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.417
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.416
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.414
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.412
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.412
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.409
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.409
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
37 |
0.402
|
|
|
|
negative regulation of calcium mediated signaling
|
GO:0050849 |
4 |
0.395
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.394
|
|
|
|
response to macrophage colony stimulating factor
|
GO:0036005 |
4 |
0.390
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.388
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.387
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.386
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.381
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.374
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.373
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
14 |
0.370
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.368
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.366
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.363
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.362
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.354
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.352
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
3 |
0.352
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
33 |
0.352
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.351
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.344
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.342
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.342
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.339
|
|
|
|
regulation of pro b cell differentiation
|
GO:2000973 |
1 |
0.337
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.333
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.325
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.325
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.318
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.318
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.316
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.314
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.313
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.309
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.305
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.305
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.305
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.303
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.300
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.297
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.292
|
|
|
|
regulation of coagulation
|
GO:0050818 |
44 |
0.290
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.288
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.287
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.284
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.282
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.281
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.275
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.272
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.269
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
29 |
0.264
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.264
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.262
|
|
|
|
regulation of epidermal growth factor receptor signaling pathway
|
GO:0042058 |
27 |
0.261
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.259
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.255
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.255
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.254
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.253
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
4 |
0.246
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.244
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.243
|
Mouse |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.243
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.240
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.239
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.237
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.232
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.232
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.231
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.231
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.230
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.227
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.226
|
|
|
|
negative regulation of b cell receptor signaling pathway
|
GO:0050859 |
2 |
0.225
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
23 |
0.224
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.222
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.222
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.220
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
39 |
0.219
|
|
|
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
38 |
0.216
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.215
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.215
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.215
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
24 |
0.210
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.209
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
10 |
0.209
|
|
|
|
mast cell activation
|
GO:0045576 |
6 |
0.208
|
Mouse |
|
|
cellular response to macrophage colony stimulating factor stimulus
|
GO:0036006 |
4 |
0.205
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.204
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.200
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
13 |
0.198
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.198
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.197
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
24 |
0.193
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.192
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.192
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
18 |
0.192
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.191
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
22 |
0.191
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.190
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.188
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
27 |
0.188
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.188
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.185
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.184
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
33 |
0.184
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.183
|
|
|
|
t cell selection
|
GO:0045058 |
4 |
0.182
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.181
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
15 |
0.180
|
|
|
|
b cell proliferation
|
GO:0042100 |
22 |
0.179
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.178
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.176
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.175
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity involved in g1 s transition of mitotic cell cycle
|
GO:0031657 |
9 |
0.172
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.171
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.171
|
|
|
|
negative regulation of t cell receptor signaling pathway
|
GO:0050860 |
4 |
0.170
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.168
|
Mouse |
|
|
regulation of lipase activity
|
GO:0060191 |
37 |
0.167
|
|
|
|
interleukin 6 mediated signaling pathway
|
GO:0070102 |
7 |
0.167
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.167
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.166
|
|
|
|
system process
|
GO:0003008 |
349 |
0.165
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.164
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.161
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.161
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.161
|
|
|
|
negative regulation of epidermal growth factor receptor signaling pathway
|
GO:0042059 |
11 |
0.158
|
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
4 |
0.155
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.153
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.153
|
|
|
|
rap protein signal transduction
|
GO:0032486 |
7 |
0.153
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.153
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.152
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.151
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.151
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.150
|
|
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.150
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
3 |
0.148
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.147
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.147
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.144
|
|
|
|
regulation of endothelial cell apoptotic process
|
GO:2000351 |
24 |
0.143
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.143
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.143
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.142
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.141
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.139
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
10 |
0.137
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.136
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.136
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.136
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.135
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.134
|
|
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
11 |
0.132
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.132
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
10 |
0.131
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.131
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.126
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.126
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.126
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.123
|
|
|
|
microtubule polymerization
|
GO:0046785 |
18 |
0.123
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.123
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.120
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.120
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.120
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.119
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.118
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.117
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.117
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.116
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.114
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.114
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.114
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.113
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.113
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.113
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.112
|
|
|
|
thymic t cell selection
|
GO:0045061 |
2 |
0.112
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.111
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.111
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.110
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.110
|
|
|
|
positive regulation of myeloid leukocyte mediated immunity
|
GO:0002888 |
1 |
0.108
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.107
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.107
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.106
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.106
|
|
|
|
tissue homeostasis
|
GO:0001894 |
63 |
0.106
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.104
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.103
|
|
|
|
positive regulation of phagocytosis
|
GO:0050766 |
15 |
0.103
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.103
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.102
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.102
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.101
|
|
|
|
platelet aggregation
|
GO:0070527 |
32 |
0.101
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.100
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.100
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.099
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.098
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
11 |
0.097
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
24 |
0.096
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.095
|
|
|
|
regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002923 |
3 |
0.095
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.095
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.095
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.094
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
21 |
0.093
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.091
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.090
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.090
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
7 |
0.089
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.087
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.087
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.087
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.085
|
|
|
|
positive regulation of lipase activity
|
GO:0060193 |
28 |
0.082
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
7 |
0.081
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.081
|
|
|
|
positive thymic t cell selection
|
GO:0045059 |
1 |
0.081
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.081
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.081
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.080
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.079
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.079
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
40 |
0.078
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.077
|
|
|
|
regulation of epidermal growth factor activated receptor activity
|
GO:0007176 |
14 |
0.075
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.075
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.075
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.075
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.075
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
47 |
0.074
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
4 |
0.074
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
4 |
0.074
|
|
|
|
fc receptor signaling pathway
|
GO:0038093 |
2 |
0.073
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.073
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.073
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.071
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.071
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.070
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.069
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.068
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.068
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.067
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.067
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.067
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.067
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.066
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.065
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.065
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.065
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.065
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
5 |
0.064
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.063
|
|
|
|
heterotypic cell cell adhesion
|
GO:0034113 |
28 |
0.063
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.062
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.062
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.061
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.061
|
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
28 |
0.061
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.060
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.059
|
Mouse |
|
|
regulation of isotype switching
|
GO:0045191 |
2 |
0.059
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.058
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.057
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
38 |
0.057
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.057
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.056
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.056
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
2 |
0.056
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.055
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.055
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.054
|
|
|
|
interleukin 1 beta production
|
GO:0032611 |
22 |
0.054
|
|
|
|
regulation of microtubule polymerization
|
GO:0031113 |
12 |
0.054
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.053
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.053
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
22 |
0.053
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.053
|
Mouse |
|
|
nerve development
|
GO:0021675 |
4 |
0.052
|
|
|
|
short term memory
|
GO:0007614 |
1 |
0.052
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
7 |
0.052
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.051
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
13 |
0.051
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
9 |
0.051
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.050
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
25 |
0.050
|
|
|
|
regulation of actin filament bundle assembly
|
GO:0032231 |
36 |
0.050
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.050
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.050
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.049
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.049
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.049
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.049
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.048
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.048
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.048
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
3 |
0.048
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.048
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.048
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.047
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.046
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.046
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.046
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
6 |
0.045
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.045
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
10 |
0.045
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.045
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
12 |
0.045
|
|
|
|
gamma delta t cell activation
|
GO:0046629 |
3 |
0.045
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.044
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.044
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.044
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.044
|
|
|
|
calcium mediated signaling using intracellular calcium source
|
GO:0035584 |
7 |
0.043
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.043
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.042
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.042
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.042
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
11 |
0.042
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.041
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.041
|
|
|
|
positive regulation of nitric oxide synthase biosynthetic process
|
GO:0051770 |
3 |
0.041
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.041
|
|
|
|
regulation of regulatory t cell differentiation
|
GO:0045589 |
4 |
0.041
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.041
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.040
|
|
|
|
phagocytosis
|
GO:0006909 |
42 |
0.040
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.040
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.039
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.039
|
|
|
|
activation of ras gtpase activity
|
GO:0032856 |
15 |
0.039
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.039
|
|
|
|
positive regulation of rap gtpase activity
|
GO:0032854 |
8 |
0.039
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
46 |
0.039
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.038
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.038
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
33 |
0.038
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.038
|
|
|
|
positive regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045737 |
15 |
0.038
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.038
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.037
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.037
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.037
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.036
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.035
|
|
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
27 |
0.035
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.035
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.035
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.035
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.034
|
|
|
|
positive regulation of muscle adaptation
|
GO:0014744 |
1 |
0.034
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.034
|
|