|
|
positive regulation of aldosterone metabolic process
|
GO:0032346 |
2 |
0.996
|
|
|
|
positive regulation of aldosterone biosynthetic process
|
GO:0032349 |
2 |
0.996
|
|
|
|
positive regulation of steroid hormone biosynthetic process
|
GO:0090031 |
2 |
0.909
|
|
|
|
positive regulation of hormone biosynthetic process
|
GO:0046886 |
4 |
0.585
|
|
|
|
aldosterone secretion
|
GO:0035932 |
1 |
0.527
|
|
|
|
positive regulation of mineralocorticoid secretion
|
GO:2000857 |
1 |
0.438
|
|
|
|
regulation of aldosterone biosynthetic process
|
GO:0032347 |
6 |
0.419
|
|
|
|
ketone biosynthetic process
|
GO:0042181 |
17 |
0.416
|
|
|
|
regulation of ketone biosynthetic process
|
GO:0010566 |
7 |
0.335
|
|
|
|
regulation of aldosterone secretion
|
GO:2000858 |
1 |
0.324
|
|
|
|
positive regulation of corticosteroid hormone secretion
|
GO:2000848 |
5 |
0.323
|
|
|
|
mineralocorticoid secretion
|
GO:0035931 |
1 |
0.246
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.244
|
|
|
|
positive regulation of aldosterone secretion
|
GO:2000860 |
1 |
0.221
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.210
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.209
|
|
|
|
regulation of mineralocorticoid secretion
|
GO:2000855 |
1 |
0.209
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.188
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.184
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.182
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.178
|
|
|
|
cellular hormone metabolic process
|
GO:0034754 |
41 |
0.173
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.163
|
|
|
|
mineralocorticoid metabolic process
|
GO:0008212 |
9 |
0.159
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.159
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.154
|
|
|
|
positive regulation of steroid biosynthetic process
|
GO:0010893 |
6 |
0.151
|
|
|
|
regulation of wnt signaling pathway planar cell polarity pathway
|
GO:2000095 |
2 |
0.148
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.146
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.146
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.145
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.143
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.143
|
|
|
|
aldosterone biosynthetic process
|
GO:0032342 |
9 |
0.141
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.139
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.129
|
|
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
18 |
0.125
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.123
|
|
|
|
steroid biosynthetic process
|
GO:0006694 |
46 |
0.122
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.120
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.116
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.114
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.114
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.110
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.110
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.106
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.105
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.105
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.105
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.101
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.101
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.101
|
|
|
|
positive regulation of alcohol biosynthetic process
|
GO:1902932 |
9 |
0.100
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.099
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.098
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.094
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.094
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.091
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.091
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.090
|
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
14 |
0.090
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.090
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.087
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.086
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.086
|
|
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.086
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.085
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.083
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.083
|
|
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
0.082
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.082
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.080
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.078
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.078
|
|
|
|
positive regulation of lipid biosynthetic process
|
GO:0046889 |
22 |
0.078
|
|
|
|
wnt signaling pathway planar cell polarity pathway
|
GO:0060071 |
5 |
0.077
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.077
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.076
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.076
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.076
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.075
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.075
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.075
|
|
|
|
regulation of steroid biosynthetic process
|
GO:0050810 |
23 |
0.075
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.075
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.074
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.074
|
|
|
|
regulation of growth rate
|
GO:0040009 |
1 |
0.074
|
|
|
|
regulation of aldosterone metabolic process
|
GO:0032344 |
6 |
0.074
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.070
|
|
|
|
mineralocorticoid biosynthetic process
|
GO:0006705 |
9 |
0.070
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.070
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.070
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.069
|
|
|
|
hormone metabolic process
|
GO:0042445 |
61 |
0.069
|
|
|
|
regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033143 |
32 |
0.069
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.068
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.067
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.067
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.067
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.066
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.066
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.066
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.065
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.065
|
|
|
|
early endosome to late endosome transport
|
GO:0045022 |
21 |
0.064
|
|
|
|
endocrine process
|
GO:0050886 |
25 |
0.063
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.062
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.062
|
|
|
|
positive regulation of non canonical wnt signaling pathway
|
GO:2000052 |
3 |
0.062
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.062
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.061
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.061
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.061
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.061
|
|
|
|
positive regulation of pathway restricted smad protein phosphorylation
|
GO:0010862 |
22 |
0.060
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.060
|
Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.060
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.060
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.059
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.059
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.058
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.058
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.058
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.058
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.057
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.056
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.056
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.056
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.056
|
Mouse |
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.054
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.054
|
|
|
|
alcohol biosynthetic process
|
GO:0046165 |
52 |
0.054
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.054
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.053
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.053
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.053
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.052
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.052
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.052
|
|
|
|
regulation of alcohol biosynthetic process
|
GO:1902930 |
22 |
0.052
|
|
|
|
c21 steroid hormone biosynthetic process
|
GO:0006700 |
11 |
0.051
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.051
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.050
|
|
|
|
membrane budding
|
GO:0006900 |
28 |
0.049
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.049
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.048
|
|
|
|
endoderm development
|
GO:0007492 |
33 |
0.047
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.047
|
Mouse |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.047
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.046
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.046
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.046
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.046
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.045
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.045
|
Mouse |
|
|
regulation of dna templated transcription elongation
|
GO:0032784 |
23 |
0.045
|
|
|
|
excretion
|
GO:0007588 |
9 |
0.045
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.045
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.045
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.045
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.045
|
Mouse |
|
|
regulation of steroid metabolic process
|
GO:0019218 |
32 |
0.044
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.044
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.044
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.044
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.044
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.044
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.044
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.044
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.043
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.043
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.043
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.043
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.043
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.042
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.042
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.042
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.042
|
Mouse |
|
|
receptor recycling
|
GO:0001881 |
15 |
0.042
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.042
|
|
|
|
steroid hormone secretion
|
GO:0035929 |
8 |
0.041
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.041
|
Mouse |
|
|
jnk cascade
|
GO:0007254 |
80 |
0.041
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.041
|
|
|
|
regulation of receptor recycling
|
GO:0001919 |
10 |
0.041
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.041
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.041
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.040
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.040
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.040
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.040
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.040
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.040
|
Mouse |
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.039
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.039
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.039
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.039
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.039
|
|
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
38 |
0.039
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.038
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.038
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.038
|
|
|
|
positive regulation of steroid hormone secretion
|
GO:2000833 |
6 |
0.038
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.038
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.038
|
|
|
|
regulation of hormone biosynthetic process
|
GO:0046885 |
10 |
0.038
|
|
|
|
system process
|
GO:0003008 |
349 |
0.037
|
Mouse |
|
|
negative regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033144 |
18 |
0.037
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.037
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.037
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.037
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.037
|
Mouse |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.036
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.036
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.036
|
|
|
|
positive regulation of early endosome to late endosome transport
|
GO:2000643 |
3 |
0.036
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.036
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.036
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.036
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.036
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.035
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.035
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.035
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.035
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.034
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.034
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.034
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.034
|
|
|
|
aldosterone metabolic process
|
GO:0032341 |
9 |
0.034
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.034
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.034
|
|
|
|
regulation of non canonical wnt signaling pathway
|
GO:2000050 |
4 |
0.034
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.033
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.033
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.033
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.033
|
|
|
|
positive regulation of integrin mediated signaling pathway
|
GO:2001046 |
2 |
0.033
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.033
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.033
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.033
|
Mouse |
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.032
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.032
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.032
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.032
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.032
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.032
|
Mouse |
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.032
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.032
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.032
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.032
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.032
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.032
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.032
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.032
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.031
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.031
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.031
|
|
|
|
regulation of protein localization to cell surface
|
GO:2000008 |
15 |
0.031
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.031
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.031
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.031
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.030
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.030
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.030
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.030
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.030
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.030
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.030
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.030
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.030
|
Mouse |
|
|
regulation of system process
|
GO:0044057 |
101 |
0.030
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.030
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.030
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.030
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.030
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.029
|
Rat |
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.029
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.029
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.029
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.029
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.029
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.029
|
|
|
|
regulation of clathrin mediated endocytosis
|
GO:2000369 |
4 |
0.028
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.028
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.028
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.028
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.028
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.028
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.027
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.027
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.027
|
|
|
|
endocrine hormone secretion
|
GO:0060986 |
13 |
0.027
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.027
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.027
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.027
|
|
|
|
isoprenoid metabolic process
|
GO:0006720 |
39 |
0.027
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.027
|
|
|
|
hormone biosynthetic process
|
GO:0042446 |
22 |
0.026
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.026
|
|
|
|
response to epidermal growth factor
|
GO:0070849 |
14 |
0.026
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.026
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.026
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.026
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.026
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.026
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.026
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.026
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.026
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.026
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.026
|
|
|
|
memory
|
GO:0007613 |
3 |
0.025
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.025
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.025
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.025
|
Mouse |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.025
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.025
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.025
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.025
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.025
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.025
|
Mouse |
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.025
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.024
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.024
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.024
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.024
|
|
|
|
pinocytosis
|
GO:0006907 |
8 |
0.024
|
|
|
|
regulation of androgen receptor signaling pathway
|
GO:0060765 |
18 |
0.024
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.024
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.024
|
|
|
|
response to interferon gamma
|
GO:0034341 |
39 |
0.024
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.024
|
|
|
|
positive regulation of steroid metabolic process
|
GO:0045940 |
13 |
0.024
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.024
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.024
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.023
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.023
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.023
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.023
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.023
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.023
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.023
|
|
|
|
regulation of corticosteroid hormone secretion
|
GO:2000846 |
5 |
0.023
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.023
|
|
|
|
positive regulation of hormone metabolic process
|
GO:0032352 |
6 |
0.023
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.023
|
|
|
|
androgen receptor signaling pathway
|
GO:0030521 |
34 |
0.023
|
|
|
|
positive regulation of hormone secretion
|
GO:0046887 |
25 |
0.023
|
|
|
|
endosome transport via multivesicular body sorting pathway
|
GO:0032509 |
3 |
0.023
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.023
|
|
|
|
growth
|
GO:0040007 |
202 |
0.022
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.022
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.022
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.022
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.022
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.022
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.022
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.022
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.022
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.022
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.021
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.021
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.021
|
Mouse |
|
|
neural tube formation
|
GO:0001841 |
3 |
0.021
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.021
|
|
|
|
dna templated transcription elongation
|
GO:0006354 |
25 |
0.021
|
|
|
|
regulation of integrin mediated signaling pathway
|
GO:2001044 |
3 |
0.021
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.021
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.021
|
|
|
|
negative regulation of neuron projection development
|
GO:0010977 |
15 |
0.021
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.021
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.021
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.021
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.021
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.021
|
|
|
|
regulation of endocrine process
|
GO:0044060 |
12 |
0.021
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.020
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.020
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.020
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.020
|
|
|
|
positive regulation of receptor mediated endocytosis
|
GO:0048260 |
21 |
0.020
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.020
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.020
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.020
|
|
|
|
regulation of substrate adhesion dependent cell spreading
|
GO:1900024 |
19 |
0.020
|
|
|
|
smad protein import into nucleus
|
GO:0007184 |
13 |
0.020
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.020
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.020
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.020
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.020
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.020
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.020
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.020
|
|
|
|
golgi vesicle transport
|
GO:0048193 |
80 |
0.019
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.019
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.019
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.019
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.019
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.019
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.019
|
|
|
|
regulation of mrna export from nucleus
|
GO:0010793 |
3 |
0.019
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.019
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.019
|
|
|
|
c21 steroid hormone metabolic process
|
GO:0008207 |
17 |
0.019
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.019
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.019
|
Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.019
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.019
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.019
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.019
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.019
|
|
|
|
negative regulation of sodium ion transmembrane transport
|
GO:1902306 |
2 |
0.019
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.019
|
|
|
|
regulation of lipid transport
|
GO:0032368 |
44 |
0.019
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.019
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.019
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.018
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.018
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.018
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.018
|
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
14 |
0.018
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.018
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.018
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.018
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.018
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.018
|
|
|
|
molting cycle process
|
GO:0022404 |
12 |
0.018
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.018
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.018
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.018
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.018
|
Mouse |
|
|
positive regulation of t cell tolerance induction
|
GO:0002666 |
2 |
0.018
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.018
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.018
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.018
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.018
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.018
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.018
|
Mouse |
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.018
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.018
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.017
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.017
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.017
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.017
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.017
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.017
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.017
|
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.017
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.017
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.017
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.017
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.017
|
|
|
|
late endosome to vacuole transport
|
GO:0045324 |
2 |
0.017
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.017
|
|
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.017
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.017
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.017
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.017
|
|
|
|
thymus development
|
GO:0048538 |
3 |
0.017
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.017
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.017
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.016
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.016
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.016
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.016
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.016
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.016
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.016
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.016
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.016
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.016
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.016
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.016
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.016
|
|
|
|
ribonucleoprotein complex export from nucleus
|
GO:0071426 |
4 |
0.016
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.016
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.016
|
|
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
45 |
0.016
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.016
|
|
