Homo sapiens

18 known processes

MGEA5

meningioma expressed antigen 5 (hyaluronidase)

(Aliases: MEA5,NCOAT,FLJ11229,FLJ23355,KIAA0679,OGA)

MGEA5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
glucosamine containing compound metabolic process GO:1901071 10 0.915
amino sugar metabolic process GO:0006040 15 0.816
protein alkylation GO:0008213 74 0.641
protein o linked glycosylation GO:0006493 21 0.590
covalent chromatin modification GO:0016569 254 0.580
peptidyl lysine methylation GO:0018022 37 0.578
methylation GO:0032259 106 0.426
histone h3 k4 methylation GO:0051568 27 0.359
histone lysine methylation GO:0034968 50 0.346
protein ubiquitination GO:0016567 314 0.321
protein modification by small protein conjugation GO:0032446 342 0.316
histone modification GO:0016570 251 0.306
chromatin modification GO:0016568 298 0.302
macromolecule methylation GO:0043414 97 0.287
histone methylation GO:0016571 60 0.278
chromatin organization GO:0006325 351 0.269
cellular response to toxic substance GO:0097237 4 0.265
small gtpase mediated signal transduction GO:0007264 78 0.239
positive regulation of cell size GO:0045793 3 0.230
ribonucleoprotein complex subunit organization GO:0071826 81 0.229
cellular ketone metabolic process GO:0042180 80 0.208
mitochondrion distribution GO:0048311 3 0.203
regulation of establishment of protein localization GO:0070201 242 0.192
protein methylation GO:0006479 74 0.186
hemopoiesis GO:0030097 180 0.175
canonical wnt signaling pathway GO:0060070 116 0.157
peptidyl threonine phosphorylation GO:0018107 41 0.156
glycogen metabolic process GO:0005977 22 0.156
Worm
ras protein signal transduction GO:0007265 73 0.155
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.153
pyruvate metabolic process GO:0006090 26 0.152
regulation of carbohydrate metabolic process GO:0006109 54 0.151
Worm
regulation of epithelial cell proliferation involved in lung morphogenesis GO:2000794 2 0.150
positive regulation of developmental process GO:0051094 314 0.148
carbohydrate metabolic process GO:0005975 207 0.144
Worm
cellular macromolecular complex assembly GO:0034622 324 0.143
regulation of protein ubiquitination GO:0031396 95 0.142
cellular response to hormone stimulus GO:0032870 125 0.142
positive regulation of organelle organization GO:0010638 195 0.140
protein localization to organelle GO:0033365 280 0.135
cellular amine metabolic process GO:0044106 41 0.133
dephosphorylation GO:0016311 209 0.131
Worm
cellular response to endogenous stimulus GO:0071495 336 0.129
positive regulation of cell differentiation GO:0045597 211 0.126
glycolytic process GO:0006096 17 0.123
regulation of canonical wnt signaling pathway GO:0060828 88 0.121
macromolecule glycosylation GO:0043413 63 0.121
Worm
glycoprotein biosynthetic process GO:0009101 91 0.120
Worm
positive regulation of cellular component organization GO:0051130 376 0.118
regulation of ras protein signal transduction GO:0046578 155 0.118
histone h4 k8 acetylation GO:0043982 15 0.117
ribonucleoprotein complex assembly GO:0022618 78 0.117
protein heterotrimerization GO:0070208 4 0.114
regulation of cellular ketone metabolic process GO:0010565 50 0.112
cellular polysaccharide metabolic process GO:0044264 27 0.111
Worm
amine metabolic process GO:0009308 44 0.107
negative regulation of cellular component organization GO:0051129 235 0.107
determination of adult lifespan GO:0008340 2 0.105
glycosylation GO:0070085 71 0.103
Worm
immune system development GO:0002520 195 0.103
histone h4 k16 acetylation GO:0043984 14 0.102
regulation of cellular amino acid metabolic process GO:0006521 6 0.100
epithelial cell proliferation involved in lung morphogenesis GO:0060502 3 0.099
negative regulation of phosphate metabolic process GO:0045936 267 0.098
carbohydrate derivative biosynthetic process GO:1901137 207 0.097
Worm
cellular response to acid chemical GO:0071229 44 0.096
hematopoietic or lymphoid organ development GO:0048534 186 0.094
cellular glucan metabolic process GO:0006073 22 0.094
Worm
regulation of histone h3 k27 methylation GO:0061085 4 0.094
glycoprotein metabolic process GO:0009100 110 0.093
Worm
ribonucleoprotein complex biogenesis GO:0022613 116 0.093
membrane organization GO:0061024 292 0.092
establishment of protein localization to membrane GO:0090150 121 0.091
histone demethylation GO:0016577 15 0.087
demethylation GO:0070988 37 0.087
cellular carbohydrate metabolic process GO:0044262 84 0.086
Worm
peptidyl lysine modification GO:0018205 144 0.086
regulation of cellular response to stress GO:0080135 244 0.085
protein dephosphorylation GO:0006470 81 0.085
Worm
regulation of cell differentiation GO:0045595 393 0.085
intracellular protein transport GO:0006886 270 0.083
post embryonic development GO:0009791 2 0.083
Worm
enzyme linked receptor protein signaling pathway GO:0007167 303 0.083
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.080
histone h4 k5 acetylation GO:0043981 15 0.080
negative regulation of protein transport GO:0051224 75 0.079
reactive oxygen species biosynthetic process GO:1903409 4 0.079
regulation of protein transport GO:0051223 213 0.078
regulation of myeloid cell differentiation GO:0045637 81 0.077
protein targeting GO:0006605 187 0.076
cellular amino acid metabolic process GO:0006520 116 0.075
regulation of small gtpase mediated signal transduction GO:0051056 156 0.074
myeloid cell differentiation GO:0030099 117 0.073
protein localization to nucleus GO:0034504 136 0.071
negative regulation of developmental process GO:0051093 247 0.071
regulation of cellular amine metabolic process GO:0033238 11 0.069
monosaccharide metabolic process GO:0005996 74 0.068
regulation of protein localization GO:0032880 296 0.066
cellular response to decreased oxygen levels GO:0036294 51 0.065
regulation of histone methylation GO:0031060 16 0.064
glucan metabolic process GO:0044042 22 0.062
Worm
response to nitrogen compound GO:1901698 184 0.061
positive regulation of phosphorylation GO:0042327 394 0.061
single organism membrane organization GO:0044802 268 0.061
cell projection organization GO:0030030 252 0.060
positive regulation of myeloid leukocyte differentiation GO:0002763 24 0.059
regulation of intracellular protein transport GO:0033157 123 0.059
peptidyl threonine modification GO:0018210 45 0.058
multicellular organismal aging GO:0010259 3 0.057
negative regulation of protein metabolic process GO:0051248 391 0.056
Worm
protein localization to membrane GO:0072657 160 0.056
cellular response to oxygen containing compound GO:1901701 276 0.055
regulation of epithelial cell proliferation GO:0050678 113 0.055
histone h4 acetylation GO:0043967 47 0.054
wnt signaling pathway GO:0016055 156 0.054
cytoplasmic transport GO:0016482 379 0.053
negative regulation of cellular amine metabolic process GO:0033239 3 0.052
negative regulation of intracellular transport GO:0032387 60 0.052
chemical homeostasis GO:0048878 306 0.052
hexose metabolic process GO:0019318 55 0.051
negative regulation of keratinocyte differentiation GO:0045617 3 0.050
response to hormone GO:0009725 175 0.050
regulation of leukocyte differentiation GO:1902105 61 0.049
organelle fission GO:0048285 149 0.049
response to bacterium GO:0009617 144 0.047
monocarboxylic acid metabolic process GO:0032787 185 0.045
negative regulation of phosphorus metabolic process GO:0010563 267 0.044
myeloid leukocyte differentiation GO:0002573 60 0.044
energy derivation by oxidation of organic compounds GO:0015980 43 0.044
Worm
protein oligomerization GO:0051259 173 0.043
rna processing GO:0006396 255 0.043
positive regulation of protein phosphorylation GO:0001934 313 0.043
regulation of intracellular transport GO:0032386 195 0.042
response to toxic substance GO:0009636 37 0.042
protein homooligomerization GO:0051260 100 0.042
cellular response to lipid GO:0071396 127 0.041
negative regulation of intracellular protein transport GO:0090317 42 0.040
mitotic cell cycle GO:0000278 326 0.040
dna repair GO:0006281 198 0.040
peptidyl lysine trimethylation GO:0018023 10 0.039
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.039
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.039
metal ion transport GO:0030001 272 0.038
single organism carbohydrate metabolic process GO:0044723 193 0.038
Worm
protein dealkylation GO:0008214 17 0.038
single organism cellular localization GO:1902580 332 0.038
negative regulation of catalytic activity GO:0043086 335 0.038
generation of precursor metabolites and energy GO:0006091 68 0.038
Worm
positive regulation of immune system process GO:0002684 283 0.038
ncrna metabolic process GO:0034660 108 0.037
response to lipid GO:0033993 206 0.037
single organism carbohydrate catabolic process GO:0044724 33 0.037
cellular chemical homeostasis GO:0055082 180 0.037
positive regulation of proteolysis GO:0045862 142 0.037
intracellular receptor signaling pathway GO:0030522 104 0.036
granulocyte differentiation GO:0030851 16 0.035
leukocyte differentiation GO:0002521 98 0.035
nervous system development GO:0007399 293 0.035
negative regulation of phosphorylation GO:0042326 174 0.035
cellular response to nitrogen compound GO:1901699 144 0.034
regulation of protein targeting GO:1903533 91 0.034
regulation of proteolysis GO:0030162 293 0.034
maintenance of location GO:0051235 112 0.034
Worm
response to biotic stimulus GO:0009607 276 0.034
phosphatidylinositol mediated signaling GO:0048015 55 0.033
negative regulation of cell differentiation GO:0045596 171 0.033
peptidyl lysine acetylation GO:0018394 101 0.032
regulation of wnt signaling pathway GO:0030111 123 0.032
cellular homeostasis GO:0019725 196 0.032
regulation of nucleotide catabolic process GO:0030811 205 0.032
circadian behavior GO:0048512 2 0.032
response to hypoxia GO:0001666 96 0.032
response to decreased oxygen levels GO:0036293 96 0.032
epithelium development GO:0060429 227 0.031
glucose homeostasis GO:0042593 31 0.030
negative regulation of cell death GO:0060548 345 0.029
response to other organism GO:0051707 261 0.029
reactive oxygen species metabolic process GO:0072593 75 0.029
protein deubiquitination GO:0016579 79 0.029
negative regulation of protein modification process GO:0031400 200 0.029
Worm
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.028
protein targeting to membrane GO:0006612 42 0.028
mitochondrion organization GO:0007005 156 0.028
regulation of chromatin organization GO:1902275 56 0.028
regulation of protein localization to nucleus GO:1900180 85 0.028
male gonad development GO:0008584 23 0.028
regulation of anatomical structure morphogenesis GO:0022603 286 0.028
positive regulation of myeloid cell differentiation GO:0045639 39 0.027
positive regulation of leukocyte differentiation GO:1902107 37 0.027
organ morphogenesis GO:0009887 147 0.027
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.027
negative regulation of peptidyl serine phosphorylation GO:0033137 8 0.027
regulation of granulocyte differentiation GO:0030852 11 0.027
carbohydrate catabolic process GO:0016052 36 0.026
rhythmic behavior GO:0007622 2 0.026
cellular component morphogenesis GO:0032989 314 0.026
epithelial cell proliferation GO:0050673 128 0.026
female gamete generation GO:0007292 2 0.026
protein demethylation GO:0006482 17 0.026
cell development GO:0048468 328 0.026
negative regulation of transport GO:0051051 176 0.026
positive regulation of histone h3 k4 methylation GO:0051571 8 0.026
response to virus GO:0009615 126 0.026
regulation of chromatin modification GO:1903308 51 0.025
endosomal transport GO:0016197 129 0.025
cellular macromolecule catabolic process GO:0044265 380 0.025
regulation of reactive oxygen species metabolic process GO:2000377 41 0.025
reproductive process GO:0022414 106 0.025
protein acetylation GO:0006473 116 0.025
positive regulation of catabolic process GO:0009896 310 0.025
gene silencing by mirna GO:0035195 23 0.025
carbohydrate homeostasis GO:0033500 31 0.024
cellular response to oxygen levels GO:0071453 55 0.024
regulation of histone modification GO:0031056 47 0.023
regulation of glucose metabolic process GO:0010906 28 0.023
cellular response to organonitrogen compound GO:0071417 124 0.023
glucose metabolic process GO:0006006 45 0.023
regulation of peptidyl serine phosphorylation GO:0033135 50 0.022
actin cytoskeleton organization GO:0030036 207 0.022
regulation of nucleocytoplasmic transport GO:0046822 98 0.022
response to oxygen levels GO:0070482 100 0.022
segmentation GO:0035282 4 0.022
oogenesis GO:0048477 2 0.022
morphogenesis of embryonic epithelium GO:0016331 4 0.022
stem cell differentiation GO:0048863 93 0.022
negative regulation of cellular protein metabolic process GO:0032269 353 0.022
Worm
mapk cascade GO:0000165 288 0.022
peptidyl serine phosphorylation GO:0018105 101 0.022
regulation of histone h3 k4 methylation GO:0051569 10 0.022
response to oxygen containing compound GO:1901700 369 0.022
negative regulation of multicellular organismal process GO:0051241 317 0.022
rna catabolic process GO:0006401 71 0.020
modification dependent macromolecule catabolic process GO:0043632 212 0.020
cardiovascular system development GO:0072358 262 0.020
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.020
regulation of anatomical structure size GO:0090066 101 0.020
spermatogenesis GO:0007283 22 0.020
circadian rhythm GO:0007623 21 0.020
regulation of purine nucleotide metabolic process GO:1900542 264 0.020
protein modification by small protein removal GO:0070646 92 0.019
male sex differentiation GO:0046661 25 0.019
negative regulation of protein ubiquitination GO:0031397 35 0.019
cellular response to hexose stimulus GO:0071331 10 0.019
positive regulation of nucleotide metabolic process GO:0045981 230 0.019
small molecule biosynthetic process GO:0044283 157 0.019
locomotory behavior GO:0007626 1 0.019
negative regulation of immune system process GO:0002683 136 0.019
purine ribonucleoside metabolic process GO:0046128 437 0.019
regulation of cellular component biogenesis GO:0044087 281 0.019
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.019
neuromuscular junction development GO:0007528 3 0.019
cellular glucose homeostasis GO:0001678 11 0.019
regulation of cytoskeleton organization GO:0051493 177 0.019
response to molecule of bacterial origin GO:0002237 82 0.019
cellular aldehyde metabolic process GO:0006081 20 0.019
negative regulation of hydrolase activity GO:0051346 182 0.019
negative regulation of organelle organization GO:0010639 126 0.019
cellular response to biotic stimulus GO:0071216 71 0.019
ncrna processing GO:0034470 83 0.019
regulation of myeloid leukocyte differentiation GO:0002761 39 0.019
mitotic cell cycle process GO:1903047 286 0.018
regulation of chromosome organization GO:0033044 103 0.018
cellular response to glucose stimulus GO:0071333 10 0.018
regulation of immune response GO:0050776 201 0.018
anatomical structure formation involved in morphogenesis GO:0048646 284 0.018
organelle localization GO:0051640 84 0.018
purine nucleoside triphosphate metabolic process GO:0009144 412 0.018
carbohydrate biosynthetic process GO:0016051 42 0.018
inositol lipid mediated signaling GO:0048017 55 0.018
posttranscriptional regulation of gene expression GO:0010608 213 0.018
actin filament based process GO:0030029 224 0.018
reproduction GO:0000003 63 0.017
internal peptidyl lysine acetylation GO:0018393 97 0.017
cellular response to lipopolysaccharide GO:0071222 57 0.017
positive regulation of protein localization to nucleus GO:1900182 48 0.017
biological adhesion GO:0022610 331 0.017
microtubule based process GO:0007017 210 0.017
rhythmic process GO:0048511 31 0.017
cellular response to molecule of bacterial origin GO:0071219 62 0.016
rna splicing GO:0008380 131 0.016
spermatid development GO:0007286 4 0.016
internal protein amino acid acetylation GO:0006475 101 0.016
regulation of cell morphogenesis GO:0022604 153 0.016
response to abiotic stimulus GO:0009628 336 0.016
regulation of response to external stimulus GO:0032101 222 0.016
microtubule cytoskeleton organization GO:0000226 176 0.016
vesicle mediated transport GO:0016192 371 0.016
cell morphogenesis GO:0000902 296 0.016
positive regulation of histone modification GO:0031058 29 0.016
protein polyubiquitination GO:0000209 110 0.015
hematopoietic stem cell differentiation GO:0060218 4 0.015
regulation of immune effector process GO:0002697 91 0.015
positive regulation of protein complex assembly GO:0031334 86 0.015
regulation of gene expression epigenetic GO:0040029 73 0.015
regulation of protein complex assembly GO:0043254 147 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
male meiosis GO:0007140 1 0.015
cell division GO:0051301 168 0.015
brain development GO:0007420 97 0.015
cellular protein catabolic process GO:0044257 261 0.015
positive regulation of chromosome organization GO:2001252 41 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.015
histone h3 k9 demethylation GO:0033169 7 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
guanosine containing compound catabolic process GO:1901069 239 0.014
cellular carbohydrate catabolic process GO:0044275 17 0.014
protein catabolic process GO:0030163 325 0.014
organelle assembly GO:0070925 176 0.014
cellular response to peptide hormone stimulus GO:0071375 56 0.014
response to retinoic acid GO:0032526 33 0.014
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.014
regulation of stem cell differentiation GO:2000736 56 0.014
lipid localization GO:0010876 106 0.014
Worm
humoral immune response GO:0006959 49 0.014
mitotic nuclear division GO:0007067 119 0.014
divalent inorganic cation transport GO:0072511 158 0.014
regulation of cell projection organization GO:0031344 107 0.014
lipid storage GO:0019915 28 0.014
Worm
organonitrogen compound biosynthetic process GO:1901566 200 0.014
autophagy GO:0006914 88 0.014
multicellular organism reproduction GO:0032504 42 0.014
protein trimerization GO:0070206 20 0.013
central nervous system development GO:0007417 123 0.013
positive regulation of cellular catabolic process GO:0031331 284 0.013
cellular response to extracellular stimulus GO:0031668 72 0.013
histone acetylation GO:0016573 93 0.013
response to organonitrogen compound GO:0010243 156 0.013
regulation of protein stability GO:0031647 87 0.013
defense response to other organism GO:0098542 129 0.013
regulation of transferase activity GO:0051338 355 0.013
positive regulation of protein transport GO:0051222 135 0.013
regulation of microtubule cytoskeleton organization GO:0070507 61 0.013
development of primary male sexual characteristics GO:0046546 23 0.013
response to peptide hormone GO:0043434 61 0.013
histone h3 k4 trimethylation GO:0080182 7 0.012
ubiquitin dependent protein catabolic process GO:0006511 206 0.012
regulation of ras gtpase activity GO:0032318 128 0.012
histone ubiquitination GO:0016574 31 0.012
mrna metabolic process GO:0016071 175 0.012
protein glycosylation GO:0006486 62 0.012
Worm
response to external biotic stimulus GO:0043207 261 0.012
ribonucleoside triphosphate catabolic process GO:0009203 391 0.012
divalent metal ion transport GO:0070838 152 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
reproductive system development GO:0061458 56 0.012
nucleocytoplasmic transport GO:0006913 176 0.012
stem cell development GO:0048864 69 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
somitogenesis GO:0001756 2 0.012
histone lysine demethylation GO:0070076 14 0.012
regulation of protein maturation GO:1903317 150 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
hematopoietic progenitor cell differentiation GO:0002244 38 0.012
regulation of generation of precursor metabolites and energy GO:0043467 27 0.012
purine ribonucleoside catabolic process GO:0046130 398 0.012
response to nutrient levels GO:0031667 81 0.012
memory GO:0007613 3 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.012
purine nucleotide catabolic process GO:0006195 405 0.012
convergent extension GO:0060026 1 0.012
nucleotide catabolic process GO:0009166 408 0.011
extrinsic apoptotic signaling pathway GO:0097191 119 0.011
regulation of lymphocyte activation GO:0051249 103 0.011
nucleoside triphosphate metabolic process GO:0009141 422 0.011
cellular response to monosaccharide stimulus GO:0071326 10 0.011
regulation of cellular carbohydrate catabolic process GO:0043471 11 0.011
positive regulation of epithelial cell proliferation GO:0050679 65 0.011
cation transport GO:0006812 331 0.011
metencephalon development GO:0022037 2 0.011
regulation of lymphocyte proliferation GO:0050670 64 0.011
embryonic epithelial tube formation GO:0001838 4 0.011
positive regulation of cytokine production GO:0001819 167 0.011
gtp metabolic process GO:0046039 239 0.011
rna interference GO:0016246 4 0.011
purine ribonucleotide catabolic process GO:0009154 404 0.011
behavior GO:0007610 112 0.011
ribonucleoside catabolic process GO:0042454 406 0.011
response to insulin GO:0032868 45 0.011
response to extracellular stimulus GO:0009991 85 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
cellular response to insulin stimulus GO:0032869 41 0.011
regulation of multi organism process GO:0043900 157 0.011
response to monosaccharide GO:0034284 20 0.010
spermatid differentiation GO:0048515 4 0.010
regulation of glycolytic process GO:0006110 10 0.010
head development GO:0060322 108 0.010
reproductive structure development GO:0048608 55 0.010
circadian regulation of gene expression GO:0032922 8 0.010
male gamete generation GO:0048232 22 0.010
immune effector process GO:0002252 159 0.010
neuroblast proliferation GO:0007405 4 0.010
protein acylation GO:0043543 138 0.010
regulation of meiotic cell cycle GO:0051445 4 0.010
positive regulation of hydrolase activity GO:0051345 331 0.010

MGEA5 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.014
disease of cellular proliferation DOID:14566 174 0.014
organ system cancer DOID:0050686 164 0.014
disease of metabolism DOID:0014667 295 0.013
central nervous system disease DOID:331 186 0.011
nervous system disease DOID:863 431 0.011