|
|
gamma aminobutyric acid signaling pathway
|
GO:0007214 |
3 |
0.943
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.484
|
|
|
|
sa node cell action potential
|
GO:0086015 |
1 |
0.378
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.378
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.370
|
|
|
|
epithelial fluid transport
|
GO:0042045 |
1 |
0.358
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.337
|
Human |
|
|
hindbrain development
|
GO:0030902 |
3 |
0.319
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.293
|
|
|
|
cell differentiation in spinal cord
|
GO:0021515 |
1 |
0.275
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.250
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.243
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.242
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.217
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.208
|
Human |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.205
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.202
|
|
|
|
membrane repolarization during sa node cell action potential
|
GO:0086052 |
1 |
0.200
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.193
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.190
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.177
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.175
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.165
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.165
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.162
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.162
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.161
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.158
|
Human |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.156
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.153
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.148
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.146
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.139
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.138
|
Human |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.137
|
Human |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.137
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.135
|
|
|
|
mating
|
GO:0007618 |
1 |
0.135
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
1 |
0.134
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.133
|
Human |
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.131
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.131
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.129
|
|
|
|
sensory perception of light stimulus
|
GO:0050953 |
35 |
0.127
|
|
|
|
neural nucleus development
|
GO:0048857 |
47 |
0.125
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.125
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.125
|
|
|
|
acetylcholine transport
|
GO:0015870 |
1 |
0.124
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.121
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.120
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.120
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.118
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.117
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.117
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.116
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.115
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.115
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.112
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.110
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.108
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.107
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.106
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.105
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.103
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.102
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.101
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.101
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.099
|
|
|
|
head development
|
GO:0060322 |
108 |
0.099
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.098
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.097
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.097
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.096
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.096
|
Human |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.096
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.096
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.095
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.095
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.095
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.095
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.094
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.093
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.093
|
Fly |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.092
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.089
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.087
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.086
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.085
|
|
|
|
amino acid transport
|
GO:0006865 |
28 |
0.085
|
|
|
|
growth
|
GO:0040007 |
202 |
0.085
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.084
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.083
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.082
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.082
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.081
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.081
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.081
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.081
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.081
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.080
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.079
|
|
|
|
ventral spinal cord development
|
GO:0021517 |
1 |
0.079
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.079
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.079
|
|
|
|
positive regulation of striated muscle contraction
|
GO:0045989 |
1 |
0.079
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.077
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.077
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.076
|
Human |
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.076
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.076
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.075
|
Fly |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.075
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.075
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.074
|
|
|
|
cardiac muscle cell action potential
|
GO:0086001 |
23 |
0.074
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.074
|
Human |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.072
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.072
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.071
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.070
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.070
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.069
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.069
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.069
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.068
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.067
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.067
|
|
|
|
system process
|
GO:0003008 |
349 |
0.066
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.066
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.065
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.065
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.064
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.063
|
Human |
|
|
negative regulation of camp mediated signaling
|
GO:0043951 |
4 |
0.063
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.063
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.063
|
|
|
|
musculoskeletal movement
|
GO:0050881 |
17 |
0.062
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.062
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.062
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.062
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.061
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.060
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.060
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.060
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.059
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.059
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.059
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.057
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.057
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.057
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.057
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.056
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.056
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.055
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.055
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.055
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.055
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.054
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.054
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.053
|
|
|
|
sulfur amino acid metabolic process
|
GO:0000096 |
14 |
0.053
|
|
|
|
thyroid hormone metabolic process
|
GO:0042403 |
4 |
0.052
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.052
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.052
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.052
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.051
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.051
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.051
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.051
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.051
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.051
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.051
|
|
|
|
negative regulation of muscle contraction
|
GO:0045932 |
3 |
0.050
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.050
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.049
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.049
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.049
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.049
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.049
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.049
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.048
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.048
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.048
|
Human |
|
|
detection of light stimulus involved in visual perception
|
GO:0050908 |
9 |
0.047
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.046
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.046
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.046
|
Human |
|
|
secretion by cell
|
GO:0032940 |
226 |
0.046
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.046
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.045
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.045
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.045
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.045
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.045
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.045
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.045
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.044
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.044
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.044
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.044
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.044
|
|
|
|
response to estradiol
|
GO:0032355 |
23 |
0.044
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.044
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.043
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.043
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.043
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.042
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.042
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.041
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.041
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.041
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.041
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.040
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.040
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.040
|
Human |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.039
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.039
|
|
|
|
hormone metabolic process
|
GO:0042445 |
61 |
0.039
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.039
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.038
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.038
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.038
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.038
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.038
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.038
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.037
|
Human |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.037
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.037
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.037
|
|
|
|
multicellular organismal movement
|
GO:0050879 |
17 |
0.037
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.037
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.037
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.036
|
|
|
|
cell differentiation in hindbrain
|
GO:0021533 |
1 |
0.036
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.036
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.036
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.035
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.035
|
|
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
64 |
0.035
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.035
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.035
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.034
|
|
|
|
sa node cell to atrial cardiac muscle cell signalling
|
GO:0086018 |
1 |
0.034
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.033
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.033
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.033
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.033
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.033
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.033
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.033
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.033
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.032
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.032
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.032
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.032
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.032
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.032
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.032
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.032
|
|
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.032
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.032
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.031
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.031
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.031
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.031
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.031
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.031
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.031
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.031
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.031
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.031
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.031
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.031
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.031
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.030
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.030
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.030
|
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
15 |
0.030
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.029
|
|
|
|
detection of visible light
|
GO:0009584 |
11 |
0.029
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.029
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.029
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.029
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.029
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.029
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.028
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.028
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.028
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.028
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.028
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.028
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.028
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.028
|
|
|
|
hormone biosynthetic process
|
GO:0042446 |
22 |
0.028
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.028
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.028
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.028
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.028
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.028
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.028
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.028
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.027
|
|
|
|
organic anion transport
|
GO:0015711 |
103 |
0.027
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.027
|
|
|
|
cerebellar cortex development
|
GO:0021695 |
1 |
0.027
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.027
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.027
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.027
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.027
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.027
|
|
|
|
negative regulation of voltage gated calcium channel activity
|
GO:1901386 |
4 |
0.027
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.026
|
|
|
|
hexose metabolic process
|
GO:0019318 |
55 |
0.026
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.026
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.026
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.026
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.026
|
|
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.026
|
|
|
|
regulation of heart rate by cardiac conduction
|
GO:0086091 |
19 |
0.025
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.025
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.025
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.025
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.025
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.025
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.025
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.025
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.025
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.025
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.025
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.025
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.025
|
|
|
|
membrane repolarization during action potential
|
GO:0086011 |
8 |
0.025
|
|
|
|
visual perception
|
GO:0007601 |
27 |
0.025
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.025
|
|
|
|
neuroblast division
|
GO:0055057 |
1 |
0.025
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.025
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.025
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.024
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.024
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.024
|
|
|
|
memory
|
GO:0007613 |
3 |
0.024
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.024
|
|
|
|
multicellular organismal macromolecule metabolic process
|
GO:0044259 |
29 |
0.024
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.024
|
|
|
|
sa node cell to atrial cardiac muscle cell communication
|
GO:0086070 |
3 |
0.024
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.024
|
|
|
|
regulation of axon guidance
|
GO:1902667 |
3 |
0.024
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.024
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.024
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.024
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.023
|
Fly |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.023
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.023
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.023
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.023
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.023
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.023
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.023
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.023
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.023
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.023
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.022
|
|
|
|
translation
|
GO:0006412 |
132 |
0.022
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.022
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.022
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.022
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.022
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.021
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.021
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.021
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.021
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.021
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.021
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.021
|
|
|
|
vasodilation
|
GO:0042311 |
4 |
0.021
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.021
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.021
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.021
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.021
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.021
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.021
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.021
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.021
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.021
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.020
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.020
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.020
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.020
|
|
|
|
neurotransmitter metabolic process
|
GO:0042133 |
5 |
0.020
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.020
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.020
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.020
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.020
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.020
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.020
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.020
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.020
|
|
|
|
thymus development
|
GO:0048538 |
3 |
0.020
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.020
|
|
|
|
anion homeostasis
|
GO:0055081 |
18 |
0.019
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.019
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.019
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.019
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.019
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.019
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.019
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.019
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.019
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.019
|
|
|
|
sensory perception of sound
|
GO:0007605 |
37 |
0.019
|
|
|
|
membrane repolarization
|
GO:0086009 |
23 |
0.019
|
|
|
|
action potential
|
GO:0001508 |
34 |
0.019
|
|
|
|
relaxation of cardiac muscle
|
GO:0055119 |
5 |
0.019
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.019
|
|
|
|
amine transport
|
GO:0015837 |
7 |
0.019
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.018
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.018
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.018
|
Human |
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.018
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.018
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.018
|
|
|
|
regulation of amine transport
|
GO:0051952 |
5 |
0.018
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.018
|
|
|
|
mitochondrial transport
|
GO:0006839 |
60 |
0.018
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.018
|
|
|
|
anatomical structure maturation
|
GO:0071695 |
9 |
0.018
|
|
|
|
acetylcholine secretion
|
GO:0061526 |
1 |
0.018
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.018
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.017
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.017
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.017
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.017
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.017
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.017
|
|
|
|
response to lithium ion
|
GO:0010226 |
2 |
0.017
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.017
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.017
|
|
|
|
glucose metabolic process
|
GO:0006006 |
45 |
0.017
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.017
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.017
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.017
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
11 |
0.017
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.017
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.017
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.017
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.017
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.017
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.017
|
Human |
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.017
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.017
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.017
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.017
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.017
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.017
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.016
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.016
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.016
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.016
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.016
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.016
|
|
|
|
regulation of heart rate
|
GO:0002027 |
38 |
0.016
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.016
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.016
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.016
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.016
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.016
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.016
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.016
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.016
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.016
|
|
|
|
cardiac conduction
|
GO:0061337 |
23 |
0.016
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.016
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.016
|
|
|
|
regulation of neuron migration
|
GO:2001222 |
3 |
0.016
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
34 |
0.016
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.016
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.016
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.016
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.016
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.016
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
32 |
0.016
|
|
|
|
regulation of striated muscle contraction
|
GO:0006942 |
37 |
0.016
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.016
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.015
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.015
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.015
|
|
