Homo sapiens

87 known processes

PGAM1

phosphoglycerate mutase 1 (brain)

(Aliases: PGAM-B,PGAMA)

PGAM1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 396 0.957
somatic muscle development GO:0007525 1 0.801
glycolytic process GO:0006096 17 0.761
somitogenesis GO:0001756 2 0.749
single organism carbohydrate metabolic process GO:0044723 193 0.650
single organism carbohydrate catabolic process GO:0044724 33 0.622
monocarboxylic acid metabolic process GO:0032787 185 0.612
nucleotide biosynthetic process GO:0009165 109 0.471
ribonucleotide biosynthetic process GO:0009260 81 0.437
myoblast fusion GO:0007520 1 0.427
post embryonic development GO:0009791 2 0.395
cellular homeostasis GO:0019725 196 0.345
carbohydrate metabolic process GO:0005975 207 0.332
carbohydrate catabolic process GO:0016052 36 0.284
anion transport GO:0006820 161 0.235
inorganic ion transmembrane transport GO:0098660 231 0.191
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.190
anatomical structure formation involved in morphogenesis GO:0048646 284 0.188
muscle cell cellular homeostasis GO:0046716 3 0.160
pyruvate metabolic process GO:0006090 26 0.152
cellular response to dna damage stimulus GO:0006974 379 0.152
nucleoside triphosphate metabolic process GO:0009141 422 0.145
ribonucleoside biosynthetic process GO:0042455 25 0.144
epithelial cell differentiation GO:0030855 141 0.136
response to other organism GO:0051707 261 0.136
cellular protein complex assembly GO:0043623 188 0.129
ribonucleoside monophosphate biosynthetic process GO:0009156 17 0.112
negative regulation of catalytic activity GO:0043086 335 0.111
atp biosynthetic process GO:0006754 11 0.111
positive regulation of transport GO:0051050 336 0.108
replicative cell aging GO:0001302 3 0.108
vesicle mediated transport GO:0016192 371 0.108
cellular amino acid metabolic process GO:0006520 116 0.104
small molecule biosynthetic process GO:0044283 157 0.095
generation of precursor metabolites and energy GO:0006091 68 0.093
myosin filament organization GO:0031033 2 0.089
cellular response to external stimulus GO:0071496 111 0.089
amine metabolic process GO:0009308 44 0.086
epithelium development GO:0060429 227 0.083
microtubule based process GO:0007017 210 0.082
determination of adult lifespan GO:0008340 2 0.080
positive regulation of cellular amine metabolic process GO:0033240 7 0.079
chordate embryonic development GO:0043009 34 0.077
glomerular mesangial cell development GO:0072144 1 0.076
embryo development GO:0009790 123 0.075
cellular response to hydrogen peroxide GO:0070301 37 0.074
response to biotic stimulus GO:0009607 276 0.074
regulation of cellular amine metabolic process GO:0033238 11 0.072
multicellular organismal aging GO:0010259 3 0.071
cellular component morphogenesis GO:0032989 314 0.070
purine ribonucleotide biosynthetic process GO:0009152 79 0.069
myosin filament assembly GO:0031034 2 0.067
positive regulation of catabolic process GO:0009896 310 0.065
metal ion transport GO:0030001 272 0.065
response to virus GO:0009615 126 0.064
cellular amine metabolic process GO:0044106 41 0.063
fructose metabolic process GO:0006000 3 0.063
ribose phosphate biosynthetic process GO:0046390 82 0.062
organonitrogen compound biosynthetic process GO:1901566 200 0.062
positive regulation of developmental process GO:0051094 314 0.061
response to external biotic stimulus GO:0043207 261 0.061
cellular calcium ion homeostasis GO:0006874 117 0.060
segmentation GO:0035282 4 0.060
cellular macromolecule catabolic process GO:0044265 380 0.057
organophosphate biosynthetic process GO:0090407 163 0.057
carbohydrate derivative biosynthetic process GO:1901137 207 0.056
regulation of protein secretion GO:0050708 86 0.055
cellular aldehyde metabolic process GO:0006081 20 0.055
endocytosis GO:0006897 159 0.054
peptidyl serine modification GO:0018209 106 0.054
regulation of anatomical structure morphogenesis GO:0022603 286 0.054
nucleoside triphosphate biosynthetic process GO:0009142 20 0.054
cation transmembrane transport GO:0098655 238 0.054
system process GO:0003008 349 0.053
Human
adult locomotory behavior GO:0008344 1 0.053
muscle contraction GO:0006936 73 0.052
Human
unsaturated fatty acid biosynthetic process GO:0006636 21 0.050
negative regulation of cell death GO:0060548 345 0.049
syncytium formation by plasma membrane fusion GO:0000768 2 0.049
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.048
negative regulation of sequestering of calcium ion GO:0051283 41 0.047
regulation of cellular ketone metabolic process GO:0010565 50 0.047
cation homeostasis GO:0055080 189 0.047
cytoplasmic transport GO:0016482 379 0.045
muscle structure development GO:0061061 98 0.045
positive regulation of binding GO:0051099 45 0.045
regulation of cellular amino acid metabolic process GO:0006521 6 0.045
spermatid development GO:0007286 4 0.044
organic acid biosynthetic process GO:0016053 97 0.043
regulation of cell cycle GO:0051726 393 0.043
aging GO:0007568 66 0.043
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.043
fatty acid metabolic process GO:0006631 115 0.043
cellular ion homeostasis GO:0006873 168 0.043
renal interstitial fibroblast development GO:0072141 1 0.042
ribonucleoside triphosphate metabolic process GO:0009199 412 0.041
anatomical structure homeostasis GO:0060249 100 0.041
pattern specification process GO:0007389 43 0.040
carboxylic acid biosynthetic process GO:0046394 97 0.040
maintenance of location GO:0051235 112 0.040
cellular carbohydrate metabolic process GO:0044262 84 0.039
regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902108 18 0.039
hexose metabolic process GO:0019318 55 0.039
purine ribonucleoside catabolic process GO:0046130 398 0.038
sex differentiation GO:0007548 45 0.038
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.037
atp metabolic process GO:0046034 176 0.037
muscle system process GO:0003012 81 0.037
Human
translesion synthesis GO:0019985 8 0.036
striated muscle myosin thick filament assembly GO:0071688 2 0.036
regulation of transmembrane transport GO:0034762 139 0.036
protein homooligomerization GO:0051260 100 0.036
vitamin metabolic process GO:0006766 26 0.035
positive regulation of nucleotide metabolic process GO:0045981 230 0.035
response to superoxide GO:0000303 6 0.035
defense response GO:0006952 315 0.035
growth GO:0040007 202 0.035
positive regulation of gtpase activity GO:0043547 166 0.034
sequestering of calcium ion GO:0051208 17 0.034
cellular divalent inorganic cation homeostasis GO:0072503 128 0.034
transmembrane transport GO:0055085 399 0.034
regulation of ion transmembrane transporter activity GO:0032412 72 0.034
response to extracellular stimulus GO:0009991 85 0.034
regulation of establishment of protein localization GO:0070201 242 0.033
positive regulation of protein secretion GO:0050714 60 0.033
regulation of protein localization GO:0032880 296 0.033
reactive oxygen species metabolic process GO:0072593 75 0.033
cofactor biosynthetic process GO:0051188 31 0.033
inorganic cation transmembrane transport GO:0098662 194 0.033
cellular response to oxidative stress GO:0034599 85 0.032
positive regulation of transporter activity GO:0032411 32 0.032
alpha amino acid metabolic process GO:1901605 72 0.031
cellular metal ion homeostasis GO:0006875 146 0.031
cellular response to extracellular stimulus GO:0031668 72 0.031
hydrogen peroxide metabolic process GO:0042743 20 0.031
locomotory behavior GO:0007626 1 0.030
purine nucleotide biosynthetic process GO:0006164 84 0.030
base excision repair GO:0006284 21 0.030
negative regulation of protein phosphatase type 2b activity GO:0032513 2 0.030
regulation of cell cycle process GO:0010564 266 0.029
cellular lipid metabolic process GO:0044255 303 0.029
nucleoside monophosphate metabolic process GO:0009123 191 0.029
rna catabolic process GO:0006401 71 0.029
negative regulation of hydrolase activity GO:0051346 182 0.029
regulation of intracellular transport GO:0032386 195 0.028
ribonucleoside triphosphate catabolic process GO:0009203 391 0.028
membrane organization GO:0061024 292 0.028
cell growth GO:0016049 160 0.027
actin filament based process GO:0030029 224 0.027
response to hormone GO:0009725 175 0.026
purine nucleotide catabolic process GO:0006195 405 0.026
positive regulation of protein transport GO:0051222 135 0.026
fructose 1 6 bisphosphate metabolic process GO:0030388 5 0.026
actin cytoskeleton organization GO:0030036 207 0.026
regulation of protein transport GO:0051223 213 0.026
taxis GO:0042330 157 0.025
innate immune response GO:0045087 178 0.025
mitochondrial outer membrane permeabilization GO:0097345 15 0.025
mitotic cell cycle process GO:1903047 286 0.024
neurological system process GO:0050877 163 0.024
protein localization to organelle GO:0033365 280 0.024
nucleoside biosynthetic process GO:0009163 26 0.024
purine nucleoside triphosphate metabolic process GO:0009144 412 0.024
mitotic cell cycle GO:0000278 326 0.024
immune response GO:0006955 307 0.023
cellular ketone metabolic process GO:0042180 80 0.023
action potential GO:0001508 34 0.023
receptor mediated endocytosis GO:0006898 84 0.023
negative regulation of cellular protein metabolic process GO:0032269 353 0.023
mitochondrial membrane organization GO:0007006 40 0.023
regulation of nucleotide metabolic process GO:0006140 269 0.023
signal transduction by phosphorylation GO:0023014 297 0.022
regulation of body fluid levels GO:0050878 99 0.022
nervous system development GO:0007399 293 0.022
organophosphate catabolic process GO:0046434 430 0.022
cation transport GO:0006812 331 0.022
meiosis i GO:0007127 4 0.021
nucleoside phosphate catabolic process GO:1901292 412 0.021
positive regulation of nucleoside metabolic process GO:0045979 186 0.021
myotube differentiation GO:0014902 22 0.021
cellular chemical homeostasis GO:0055082 180 0.021
tube development GO:0035295 125 0.021
negative regulation of apoptotic process GO:0043066 316 0.021
negative regulation of protein processing GO:0010955 142 0.021
glycosyl compound catabolic process GO:1901658 413 0.021
purine ribonucleoside metabolic process GO:0046128 437 0.021
gonad development GO:0008406 34 0.021
sequestering of metal ion GO:0051238 24 0.020
secretion GO:0046903 254 0.020
organelle assembly GO:0070925 176 0.020
establishment of nucleus localization GO:0040023 1 0.020
deoxyribose phosphate metabolic process GO:0019692 6 0.020
response to activity GO:0014823 0 0.019
intrinsic apoptotic signaling pathway GO:0097193 127 0.019
positive regulation of phosphorylation GO:0042327 394 0.019
response to acid chemical GO:0001101 66 0.019
purine nucleoside triphosphate catabolic process GO:0009146 392 0.019
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.019
regulation of cell morphogenesis GO:0022604 153 0.019
response to oxygen containing compound GO:1901700 369 0.019
regulation of apoptotic signaling pathway GO:2001233 175 0.019
regulation of binding GO:0051098 111 0.019
glucan metabolic process GO:0044042 22 0.019
reproductive system development GO:0061458 56 0.018
ribonucleoside monophosphate metabolic process GO:0009161 187 0.018
calcium ion transport GO:0006816 147 0.018
embryo development ending in birth or egg hatching GO:0009792 34 0.018
purine containing compound biosynthetic process GO:0072522 88 0.018
dephosphorylation GO:0016311 209 0.018
actomyosin structure organization GO:0031032 59 0.018
positive regulation of ion transport GO:0043270 87 0.018
fear response GO:0042596 0 0.018
cellular response to hormone stimulus GO:0032870 125 0.018
positive regulation of transmembrane transport GO:0034764 41 0.018
reproductive structure development GO:0048608 55 0.018
negative regulation of homeostatic process GO:0032845 59 0.018
response to mechanical stimulus GO:0009612 51 0.018
spermatid differentiation GO:0048515 4 0.018
positive regulation of cellular catabolic process GO:0031331 284 0.017
ribonucleoside catabolic process GO:0042454 406 0.017
positive regulation of protein phosphorylation GO:0001934 313 0.017
regulation of protein maturation GO:1903317 150 0.017
regulation of cellular component movement GO:0051270 334 0.017
apoptotic mitochondrial changes GO:0008637 57 0.017
regulation of cytokine production GO:0001817 232 0.017
cell part morphogenesis GO:0032990 137 0.017
regulation of homeostatic process GO:0032844 121 0.017
regulation of cellular response to stress GO:0080135 244 0.016
cell cycle phase transition GO:0044770 173 0.016
muscle cell differentiation GO:0042692 63 0.016
negative regulation of endopeptidase activity GO:0010951 84 0.016
regulation of growth GO:0040008 165 0.016
reproduction GO:0000003 63 0.016
cell morphogenesis GO:0000902 296 0.016
dna integrity checkpoint GO:0031570 71 0.016
monocarboxylic acid biosynthetic process GO:0072330 67 0.016
regulation of mitotic cell cycle phase transition GO:1901990 118 0.016
purine ribonucleoside biosynthetic process GO:0046129 23 0.016
regulation of viral process GO:0050792 103 0.016
immune effector process GO:0002252 159 0.016
dna repair GO:0006281 198 0.016
mitochondrion organization GO:0007005 156 0.015
reactive oxygen species biosynthetic process GO:1903409 4 0.015
negative regulation of protein metabolic process GO:0051248 391 0.015
negative regulation of camp mediated signaling GO:0043951 4 0.015
urate metabolic process GO:0046415 11 0.015
neural tube formation GO:0001841 3 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.015
regulation of cytoplasmic transport GO:1903649 149 0.015
anterior posterior axis specification embryo GO:0008595 2 0.015
glycosyl compound biosynthetic process GO:1901659 27 0.015
purine nucleoside monophosphate metabolic process GO:0009126 186 0.015
response to steroid hormone GO:0048545 80 0.015
tissue regeneration GO:0042246 3 0.015
response to hydrogen peroxide GO:0042542 40 0.015
single organism reproductive process GO:0044702 98 0.015
mapk cascade GO:0000165 288 0.014
positive regulation of hydrolase activity GO:0051345 331 0.014
response to bacterium GO:0009617 144 0.014
signal transduction in response to dna damage GO:0042770 57 0.014
negative regulation of growth GO:0045926 97 0.014
negative regulation of translation GO:0017148 37 0.014
nucleocytoplasmic transport GO:0006913 176 0.014
sulfur compound metabolic process GO:0006790 101 0.014
positive regulation of growth GO:0045927 58 0.014
cellular response to glucocorticoid stimulus GO:0071385 4 0.014
regulation of kinase activity GO:0043549 314 0.014
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway GO:1901029 4 0.014
monosaccharide metabolic process GO:0005996 74 0.014
organic anion transport GO:0015711 103 0.014
cellular respiration GO:0045333 21 0.014
peptidyl cysteine modification GO:0018198 9 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
striated muscle cell differentiation GO:0051146 43 0.014
extrinsic apoptotic signaling pathway GO:0097191 119 0.013
defense response to other organism GO:0098542 129 0.013
purine nucleoside monophosphate biosynthetic process GO:0009127 16 0.013
protein secretion GO:0009306 98 0.013
lipid transport GO:0006869 90 0.013
positive regulation of gtp catabolic process GO:0033126 166 0.013
ion homeostasis GO:0050801 230 0.013
ion transmembrane transport GO:0034220 338 0.013
positive regulation of mapk cascade GO:0043410 190 0.013
regulation of fibroblast proliferation GO:0048145 32 0.013
nitrogen compound transport GO:0071705 191 0.013
response to inorganic substance GO:0010035 127 0.013
regulation of secretion GO:0051046 194 0.013
regulation of nucleoside metabolic process GO:0009118 209 0.013
regulation of mitochondrial membrane permeability GO:0046902 25 0.013
development of primary sexual characteristics GO:0045137 35 0.013
regulation of peptidyl serine phosphorylation GO:0033135 50 0.013
positive regulation of synaptic transmission GO:0050806 4 0.012
regulation of transmembrane transporter activity GO:0022898 74 0.012
regulation of release of cytochrome c from mitochondria GO:0090199 29 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
positive regulation of secretion by cell GO:1903532 108 0.012
response to radiation GO:0009314 151 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.012
leukocyte mediated immunity GO:0002443 59 0.012
regulation of lipase activity GO:0060191 37 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.012
negative regulation of transport GO:0051051 176 0.012
organelle fission GO:0048285 149 0.012
positive regulation of secretion GO:0051047 116 0.012
regulation of protein processing GO:0070613 150 0.012
developmental growth GO:0048589 48 0.012
cell projection organization GO:0030030 252 0.011
regulation of anatomical structure size GO:0090066 101 0.011
regulation of cell growth GO:0001558 135 0.011
response to abiotic stimulus GO:0009628 336 0.011
engulfment of apoptotic cell GO:0043652 2 0.011
purine nucleoside catabolic process GO:0006152 398 0.011
peptidyl cysteine oxidation GO:0018171 1 0.011
release of sequestered calcium ion into cytosol GO:0051209 41 0.011
cytokine secretion GO:0050663 64 0.011
behavior GO:0007610 112 0.011
ribonucleoside bisphosphate biosynthetic process GO:0034030 4 0.011
positive regulation of programmed cell death GO:0043068 249 0.011
lipid storage GO:0019915 28 0.011
negative regulation of phosphatase activity GO:0010923 61 0.011
lipid biosynthetic process GO:0008610 177 0.011
cellular cation homeostasis GO:0030003 163 0.011
cell development GO:0048468 328 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
response to hypoxia GO:0001666 96 0.011
mitotic dna integrity checkpoint GO:0044774 30 0.011
brain development GO:0007420 97 0.011
chemical homeostasis GO:0048878 306 0.011
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.011
blood coagulation GO:0007596 76 0.011
lymphocyte activation GO:0046649 133 0.011
response to lipid GO:0033993 206 0.010
metal ion homeostasis GO:0055065 169 0.010
negative regulation of intracellular signal transduction GO:1902532 183 0.010
ribonucleoprotein complex biogenesis GO:0022613 116 0.010
negative regulation of response to dna damage stimulus GO:2001021 33 0.010
negative regulation of phosphorylation GO:0042326 174 0.010
head development GO:0060322 108 0.010
regulation of secretion by cell GO:1903530 177 0.010
purine nucleoside monophosphate catabolic process GO:0009128 158 0.010
protein acylation GO:0043543 138 0.010
nuclear import GO:0051170 106 0.010
negative regulation of cell growth GO:0030308 83 0.010
amide transport GO:0042886 76 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.010
positive regulation of immune system process GO:0002684 283 0.010
reproductive process GO:0022414 106 0.010

PGAM1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.258
acquired metabolic disease DOID:0060158 58 0.258
carbohydrate metabolism disease DOID:0050013 32 0.137
glucose metabolism disease DOID:4194 32 0.112
immune system disease DOID:2914 155 0.016
hematopoietic system disease DOID:74 100 0.016