Homo sapiens

85 known processes

AKR1C1

aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)

(Aliases: DDH1,DD1,H-37,MBAB,MGC8954,HAKRC,C9,DDH,20-ALPHA-HSD,2-ALPHA-HSD)

AKR1C1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
testosterone biosynthetic process GO:0061370 2 1.000
Human
androgen biosynthetic process GO:0006702 3 1.000
Human
regulation of testosterone biosynthetic process GO:2000224 2 1.000
Human
retinoic acid biosynthetic process GO:0002138 2 1.000
Human
sesquiterpenoid metabolic process GO:0006714 3 1.000
Human
diterpenoid biosynthetic process GO:0016102 2 1.000
Human
negative regulation of isoprenoid metabolic process GO:0045827 1 1.000
Human
regulation of isoprenoid metabolic process GO:0019747 1 1.000
Human
diterpenoid metabolic process GO:0016101 20 1.000
retinoic acid metabolic process GO:0042573 7 1.000
Human
sterol catabolic process GO:0016127 3 1.000
Human
primary alcohol metabolic process GO:0034308 17 1.000
Human
retinoid metabolic process GO:0001523 18 1.000
cellular response to prostaglandin stimulus GO:0071379 4 1.000
Human
polyketide metabolic process GO:0030638 8 1.000
cellular response to jasmonic acid stimulus GO:0071395 4 1.000
isoprenoid catabolic process GO:0008300 7 1.000
Human
cholesterol catabolic process GO:0006707 3 0.999
Human
hormone catabolic process GO:0042447 4 0.999
Mouse
aminoglycoside antibiotic metabolic process GO:0030647 8 0.998
regulation of retinoic acid biosynthetic process GO:1900052 1 0.998
Human
glycoside metabolic process GO:0016137 13 0.997
response to jasmonic acid GO:0009753 4 0.997
ketone biosynthetic process GO:0042181 17 0.996
Human
regulation of ketone biosynthetic process GO:0010566 7 0.996
Human
retinal metabolic process GO:0042574 8 0.994
bile acid metabolic process GO:0008206 14 0.994
terpenoid catabolic process GO:0016115 5 0.991
Human
terpenoid metabolic process GO:0006721 27 0.990
daunorubicin metabolic process GO:0044597 8 0.990
sesquiterpenoid catabolic process GO:0016107 2 0.990
Human
prostanoid metabolic process GO:0006692 17 0.988
Human
unsaturated fatty acid metabolic process GO:0033559 37 0.987
Human
c21 steroid hormone metabolic process GO:0008207 17 0.986
farnesol metabolic process GO:0016487 2 0.982
Human
farnesol catabolic process GO:0016488 2 0.979
Human
limbic system development GO:0021761 3 0.979
Rat
terpenoid biosynthetic process GO:0016114 2 0.977
Human
cofactor metabolic process GO:0051186 87 0.977
bile acid biosynthetic process GO:0006699 10 0.972
Human
quinone metabolic process GO:1901661 18 0.969
primary alcohol catabolic process GO:0034310 3 0.965
Human
fatty acid metabolic process GO:0006631 115 0.960
Human
lipid catabolic process GO:0016042 84 0.958
Human Mouse
cellular hormone metabolic process GO:0034754 41 0.956
cellular lipid catabolic process GO:0044242 65 0.955
Human
negative regulation of hormone metabolic process GO:0032351 6 0.954
Human
steroid metabolic process GO:0008202 94 0.954
carboxylic acid biosynthetic process GO:0046394 97 0.950
Human
negative regulation of lipid metabolic process GO:0045833 38 0.948
Human
small molecule biosynthetic process GO:0044283 157 0.947
Human
organic acid biosynthetic process GO:0016053 97 0.947
Human
regulation of hormone metabolic process GO:0032350 14 0.942
Human
cellular response to calcium ion GO:0071277 19 0.933
Human
hormone metabolic process GO:0042445 61 0.933
oxidation reduction process GO:0055114 396 0.933
small molecule catabolic process GO:0044282 92 0.923
Human Mouse
cellular ketone metabolic process GO:0042180 80 0.914
alcohol metabolic process GO:0006066 114 0.911
Human
regulation of cellular ketone metabolic process GO:0010565 50 0.906
Human
multicellular organismal metabolic process GO:0044236 34 0.903
Human
isoprenoid metabolic process GO:0006720 39 0.903
g protein coupled receptor signaling pathway GO:0007186 207 0.902
Human
cellular lipid metabolic process GO:0044255 303 0.888
monocarboxylic acid biosynthetic process GO:0072330 67 0.873
Human
organic hydroxy compound catabolic process GO:1901616 22 0.873
Human
lipid biosynthetic process GO:0008610 177 0.872
Human
regulation of hormone biosynthetic process GO:0046885 10 0.866
Human
organic hydroxy compound metabolic process GO:1901615 147 0.855
keratinocyte differentiation GO:0030216 36 0.851
Human
prostaglandin metabolic process GO:0006693 17 0.849
Human
hippocampus development GO:0021766 1 0.845
Rat
isoprenoid biosynthetic process GO:0008299 9 0.844
Human
response to calcium ion GO:0051592 46 0.831
Human
lipid metabolic process GO:0006629 381 0.831
parturition GO:0007567 1 0.827
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 41 0.822
Human
androgen metabolic process GO:0008209 9 0.815
Human
icosanoid metabolic process GO:0006690 35 0.814
Human
regulation of steroid biosynthetic process GO:0050810 23 0.808
Human
hormone biosynthetic process GO:0042446 22 0.807
Human
doxorubicin metabolic process GO:0044598 8 0.796
vitamin metabolic process GO:0006766 26 0.793
Human
regulation of lipid metabolic process GO:0019216 96 0.790
Human
negative regulation of retinoic acid biosynthetic process GO:1900053 1 0.777
Human
regulation of lipid biosynthetic process GO:0046890 47 0.776
Human
cellular response to endogenous stimulus GO:0071495 336 0.768
fatty acid derivative metabolic process GO:1901568 35 0.755
Human
regulation of endothelial cell apoptotic process GO:2000351 24 0.755
Human
epidermal cell differentiation GO:0009913 45 0.750
Human
multicellular organismal macromolecule metabolic process GO:0044259 29 0.749
Human
response to fatty acid GO:0070542 13 0.737
Human
regulation of hormone levels GO:0010817 125 0.737
cellular response to metal ion GO:0071248 43 0.737
Human
organic hydroxy compound biosynthetic process GO:1901617 71 0.727
Human
skin development GO:0043588 76 0.724
Human
cellular response to organic cyclic compound GO:0071407 127 0.721
Human
intracellular receptor signaling pathway GO:0030522 104 0.721
Human
steroid catabolic process GO:0006706 10 0.717
Human Mouse
secondary metabolic process GO:0019748 17 0.701
cholesterol metabolic process GO:0008203 28 0.700
Human
cellular response to oxidative stress GO:0034599 85 0.686
Human
steroid biosynthetic process GO:0006694 46 0.686
Human
reactive oxygen species metabolic process GO:0072593 75 0.684
Human
protein homooligomerization GO:0051260 100 0.682
regulation of alcohol biosynthetic process GO:1902930 22 0.665
Human
sterol metabolic process GO:0016125 28 0.663
Human
regulation of steroid metabolic process GO:0019218 32 0.642
Human
regulation of vitamin metabolic process GO:0030656 9 0.637
Human
regulation of retinoic acid receptor signaling pathway GO:0048385 9 0.632
Human
response to organophosphorus GO:0046683 41 0.630
cellular aldehyde metabolic process GO:0006081 20 0.619
negative regulation of vitamin metabolic process GO:0046137 6 0.618
Human
cellular response to oxygen containing compound GO:1901701 276 0.600
male sex differentiation GO:0046661 25 0.597
Human
positive regulation of endothelial cell apoptotic process GO:2000353 8 0.592
Human
male gonad development GO:0008584 23 0.582
Human
response to oxygen containing compound GO:1901700 369 0.581
response to lipid GO:0033993 206 0.580
Human Rat
retinoic acid receptor signaling pathway GO:0048384 13 0.572
Human
cellular response to reactive oxygen species GO:0034614 50 0.569
Human
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.561
Human
response to estrogen GO:0043627 47 0.557
Rat
alcohol biosynthetic process GO:0046165 52 0.555
Human
protein oligomerization GO:0051259 173 0.538
response to hormone GO:0009725 175 0.533
endothelial cell apoptotic process GO:0072577 26 0.531
Human
response to organic cyclic compound GO:0014070 204 0.531
Human Rat
epithelial cell differentiation GO:0030855 141 0.528
cellular response to external stimulus GO:0071496 111 0.524
Human
positive regulation of programmed cell death GO:0043068 249 0.515
Human
positive regulation of cell proliferation GO:0008284 301 0.513
Human
alcohol catabolic process GO:0046164 20 0.510
Human
epidermis development GO:0008544 59 0.510
Human
cellular response to starvation GO:0009267 58 0.484
Human
protein import GO:0017038 130 0.483
Human
response to reactive oxygen species GO:0000302 61 0.481
Human
protein import into nucleus GO:0006606 104 0.476
Human
rna splicing GO:0008380 131 0.469
positive regulation of cell death GO:0010942 263 0.467
Human
progesterone metabolic process GO:0042448 6 0.460
protein localization to organelle GO:0033365 280 0.447
Human
positive regulation of apoptotic process GO:0043065 246 0.446
Human
response to oxidative stress GO:0006979 121 0.438
Human
single organism cellular localization GO:1902580 332 0.438
Human
cellular response to lipid GO:0071396 127 0.436
Human
response to nutrient GO:0007584 20 0.432
Human
cytoplasmic transport GO:0016482 379 0.431
Human
digestion GO:0007586 22 0.427
cellular response to inorganic substance GO:0071241 45 0.426
Human
nuclear transport GO:0051169 179 0.416
Human
protein localization to nucleus GO:0034504 136 0.410
Human
nucleocytoplasmic transport GO:0006913 176 0.410
Human
response to steroid hormone GO:0048545 80 0.400
Human Rat
negative regulation of lipid biosynthetic process GO:0051055 22 0.399
Human
telencephalon development GO:0021537 17 0.393
Rat
response to drug GO:0042493 81 0.377
Rat
response to inorganic substance GO:0010035 127 0.370
Human
response to acid chemical GO:0001101 66 0.352
response to corticosteroid GO:0031960 15 0.338
Human
monocarboxylic acid metabolic process GO:0032787 185 0.337
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.327
protein targeting GO:0006605 187 0.327
Human
cellular response to corticosteroid stimulus GO:0071384 5 0.326
Human
nuclear import GO:0051170 106 0.317
Human
forebrain development GO:0030900 26 0.314
Rat
response to extracellular stimulus GO:0009991 85 0.300
Human
epithelium development GO:0060429 227 0.300
protein kinase b signaling GO:0043491 69 0.282
Human
regulation of rna splicing GO:0043484 62 0.281
mrna metabolic process GO:0016071 175 0.272
cellular response to fatty acid GO:0071398 8 0.270
Human
rna processing GO:0006396 255 0.270
response to cadmium ion GO:0046686 10 0.244
Human
negative regulation of mrna metabolic process GO:1903312 15 0.240
single organism nuclear import GO:1902593 104 0.240
Human
regulation of protein kinase b signaling GO:0051896 61 0.237
Human
response to metal ion GO:0010038 84 0.235
Human
protein targeting to nucleus GO:0044744 104 0.232
Human
regulation of mrna splicing via spliceosome GO:0048024 32 0.228
response to nutrient levels GO:0031667 81 0.225
Human
nervous system development GO:0007399 293 0.220
Rat
establishment of protein localization to organelle GO:0072594 172 0.210
Human
cellular response to nutrient levels GO:0031669 69 0.209
Human
cellular response to hormone stimulus GO:0032870 125 0.207
cell type specific apoptotic process GO:0097285 125 0.200
Human
response to starvation GO:0042594 59 0.199
Human
cellular amino acid metabolic process GO:0006520 116 0.193
response to prostaglandin GO:0034694 8 0.180
Human
protein import into nucleus translocation GO:0000060 22 0.176
Human
cellular response to steroid hormone stimulus GO:0071383 37 0.176
Human
central nervous system development GO:0007417 123 0.171
Rat
rna splicing via transesterification reactions GO:0000375 90 0.171
cellular response to acid chemical GO:0071229 44 0.153
brain development GO:0007420 97 0.144
Rat
cellular response to cadmium ion GO:0071276 8 0.132
Human
negative regulation of rna splicing GO:0033119 15 0.099
regulation of mrna processing GO:0050684 48 0.097
development of primary male sexual characteristics GO:0046546 23 0.094
Human
regulation of cellular amino acid metabolic process GO:0006521 6 0.086
cellular response to extracellular stimulus GO:0031668 72 0.079
Human
head development GO:0060322 108 0.078
Rat
mrna processing GO:0006397 133 0.077
positive regulation of cellular amine metabolic process GO:0033240 7 0.074
negative regulation of mrna splicing via spliceosome GO:0048025 11 0.068
single organism reproductive process GO:0044702 98 0.067
Human
organic anion transport GO:0015711 103 0.065
post embryonic development GO:0009791 2 0.065
cellular amine metabolic process GO:0044106 41 0.065
amine metabolic process GO:0009308 44 0.062
reproductive structure development GO:0048608 55 0.060
Human
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.057
regulation of cellular amine metabolic process GO:0033238 11 0.053
mrna splicing via spliceosome GO:0000398 89 0.048
positive regulation of transport GO:0051050 336 0.047
regulation of proteolysis GO:0030162 293 0.047
negative regulation of protein metabolic process GO:0051248 391 0.046
transmembrane transport GO:0055085 399 0.044
regulation of cellular component movement GO:0051270 334 0.042
determination of adult lifespan GO:0008340 2 0.040
cardiovascular system development GO:0072358 262 0.039
multicellular organismal aging GO:0010259 3 0.038
gonad development GO:0008406 34 0.038
Human
cation transport GO:0006812 331 0.037
negative regulation of catalytic activity GO:0043086 335 0.037
cation homeostasis GO:0055080 189 0.036
negative regulation of cell death GO:0060548 345 0.036
regulation of cell motility GO:2000145 299 0.036
regulation of response to wounding GO:1903034 101 0.036
biological adhesion GO:0022610 331 0.035
apoptotic signaling pathway GO:0097190 268 0.035
lipid transport GO:0006869 90 0.034
positive regulation of cellular catabolic process GO:0031331 284 0.034
anion transport GO:0006820 161 0.034
single organism carbohydrate metabolic process GO:0044723 193 0.034
positive regulation of cellular component organization GO:0051130 376 0.034
female gamete generation GO:0007292 2 0.034
regulation of mrna metabolic process GO:1903311 53 0.033
response to nitrogen compound GO:1901698 184 0.033
reproductive system development GO:0061458 56 0.032
Human
regulation of response to external stimulus GO:0032101 222 0.032
cell adhesion GO:0007155 325 0.032
system process GO:0003008 349 0.032
negative regulation of cellular protein metabolic process GO:0032269 353 0.032
negative regulation of apoptotic process GO:0043066 316 0.031
signal transduction by phosphorylation GO:0023014 297 0.031
negative regulation of programmed cell death GO:0043069 321 0.031
positive regulation of phosphorylation GO:0042327 394 0.030
response to biotic stimulus GO:0009607 276 0.030
mapk cascade GO:0000165 288 0.030
regulation of locomotion GO:0040012 329 0.030
regeneration GO:0031099 4 0.030
ras protein signal transduction GO:0007265 73 0.029
regulation of apoptotic signaling pathway GO:2001233 175 0.029
enzyme linked receptor protein signaling pathway GO:0007167 303 0.029
negative regulation of cell proliferation GO:0008285 228 0.029
immune response GO:0006955 307 0.029
organonitrogen compound biosynthetic process GO:1901566 200 0.028
chemical homeostasis GO:0048878 306 0.028
lipid localization GO:0010876 106 0.028
negative regulation of phosphorus metabolic process GO:0010563 267 0.028
development of primary sexual characteristics GO:0045137 35 0.028
Human
response to other organism GO:0051707 261 0.028
regulation of anatomical structure morphogenesis GO:0022603 286 0.028
purine nucleotide catabolic process GO:0006195 405 0.027
negative regulation of phosphate metabolic process GO:0045936 267 0.027
ion homeostasis GO:0050801 230 0.027
ameboidal type cell migration GO:0001667 135 0.027
nitrogen compound transport GO:0071705 191 0.027
cellular component morphogenesis GO:0032989 314 0.027
purine ribonucleoside catabolic process GO:0046130 398 0.027
cytokine production GO:0001816 247 0.027
oogenesis GO:0048477 2 0.026
intracellular protein transport GO:0006886 270 0.026
Human
regulation of cell differentiation GO:0045595 393 0.026
regulation of transferase activity GO:0051338 355 0.026
reproductive process GO:0022414 106 0.026
Human Mouse
response to wounding GO:0009611 168 0.025
metal ion transport GO:0030001 272 0.025
maintenance of location GO:0051235 112 0.025
positive regulation of protein phosphorylation GO:0001934 313 0.025
ribonucleoside triphosphate catabolic process GO:0009203 391 0.025
cellular homeostasis GO:0019725 196 0.025
multi multicellular organism process GO:0044706 18 0.025
Mouse
negative regulation of multicellular organismal process GO:0051241 317 0.025
ribonucleoside triphosphate metabolic process GO:0009199 412 0.025
response to abiotic stimulus GO:0009628 336 0.025
actin filament based process GO:0030029 224 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.025
defense response GO:0006952 315 0.025
multi organism reproductive process GO:0044703 54 0.025
Mouse
purine containing compound catabolic process GO:0072523 411 0.024
purine ribonucleoside metabolic process GO:0046128 437 0.024
small gtpase mediated signal transduction GO:0007264 78 0.024
ribonucleoside catabolic process GO:0042454 406 0.024
anatomical structure formation involved in morphogenesis GO:0048646 284 0.024
positive regulation of hydrolase activity GO:0051345 331 0.024
protein maturation GO:0051604 233 0.024
positive regulation of locomotion GO:0040017 186 0.024
nucleoside triphosphate catabolic process GO:0009143 394 0.024
segmentation GO:0035282 4 0.024
cell development GO:0048468 328 0.024
regulation of cell adhesion GO:0030155 166 0.023
positive regulation of cellular component movement GO:0051272 181 0.023
angiogenesis GO:0001525 147 0.023
regulation of protein transport GO:0051223 213 0.023
positive regulation of cell differentiation GO:0045597 211 0.023
epithelium migration GO:0090132 119 0.023
hindbrain development GO:0030902 3 0.023
single organism membrane organization GO:0044802 268 0.023
cellular response to growth factor stimulus GO:0071363 197 0.023
nucleoside catabolic process GO:0009164 408 0.022
epithelial cell migration GO:0010631 119 0.022
purine nucleoside triphosphate catabolic process GO:0009146 392 0.022
regulation of cellular component biogenesis GO:0044087 281 0.022
peptidyl tyrosine phosphorylation GO:0018108 170 0.022
memory GO:0007613 3 0.022
negative regulation of cellular component movement GO:0051271 106 0.022
regulation of cell migration GO:0030334 289 0.022
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.022
epidermis morphogenesis GO:0048730 3 0.022
organophosphate catabolic process GO:0046434 430 0.022
purine nucleoside catabolic process GO:0006152 398 0.022
ribonucleotide catabolic process GO:0009261 405 0.021
regulation of protein processing GO:0070613 150 0.021
regulation of cell cycle GO:0051726 393 0.021
negative regulation of developmental process GO:0051093 247 0.021
protein catabolic process GO:0030163 325 0.021
sex differentiation GO:0007548 45 0.021
Human
salivary gland morphogenesis GO:0007435 4 0.021
reactive oxygen species biosynthetic process GO:1903409 4 0.021
anterior posterior axis specification GO:0009948 2 0.021
positive regulation of catabolic process GO:0009896 310 0.021
regulation of cytokine production GO:0001817 232 0.021
purine ribonucleotide catabolic process GO:0009154 404 0.020
cell morphogenesis GO:0000902 296 0.020
cellular macromolecular complex assembly GO:0034622 324 0.020
response to growth factor GO:0070848 205 0.020
purine nucleoside triphosphate metabolic process GO:0009144 412 0.020
regulation of protein localization GO:0032880 296 0.020
negative regulation of cellular component organization GO:0051129 235 0.020
regulation of protein kinase activity GO:0045859 289 0.020
inorganic cation transmembrane transport GO:0098662 194 0.020
metal ion homeostasis GO:0055065 169 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.020
regulation of cellular response to stress GO:0080135 244 0.020
positive regulation of developmental process GO:0051094 314 0.020
regulation of mapk cascade GO:0043408 262 0.020
regulation of kinase activity GO:0043549 314 0.019
regulation of peptidase activity GO:0052547 180 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.019
peptidyl tyrosine modification GO:0018212 170 0.019
wound healing GO:0042060 115 0.019
carbohydrate metabolic process GO:0005975 207 0.019
innate immune response GO:0045087 178 0.019
negative regulation of apoptotic signaling pathway GO:2001234 97 0.019
tissue regeneration GO:0042246 3 0.019
nucleoside triphosphate metabolic process GO:0009141 422 0.019
cellular macromolecule catabolic process GO:0044265 380 0.019
peripheral nervous system development GO:0007422 2 0.019
coenzyme metabolic process GO:0006732 65 0.019
protein processing GO:0016485 226 0.019
spermatid differentiation GO:0048515 4 0.019
single organismal cell cell adhesion GO:0016337 148 0.019
nucleoside phosphate catabolic process GO:1901292 412 0.019
regulation of defense response GO:0031347 154 0.019
reactive nitrogen species metabolic process GO:2001057 3 0.019
negative regulation of hydrolase activity GO:0051346 182 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.019
organic acid transport GO:0015849 65 0.019
secretion GO:0046903 254 0.019
fatty acid omega oxidation GO:0010430 2 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.018
vesicle mediated transport GO:0016192 371 0.018
extrinsic apoptotic signaling pathway GO:0097191 119 0.018
mitotic cell cycle GO:0000278 326 0.018
positive regulation of secretion GO:0051047 116 0.018
negative regulation of protein modification process GO:0031400 200 0.018
endothelial cell migration GO:0043542 86 0.018
positive regulation of transferase activity GO:0051347 227 0.018
response to organonitrogen compound GO:0010243 156 0.018
circulatory system development GO:0072359 262 0.018
vasculature development GO:0001944 181 0.018
glial cell migration GO:0008347 4 0.018
cell growth GO:0016049 160 0.018
cellular protein catabolic process GO:0044257 261 0.018
ion transmembrane transport GO:0034220 338 0.018
regulation of establishment of protein localization GO:0070201 242 0.018
regulation of cytoskeleton organization GO:0051493 177 0.018
positive regulation of nucleotide metabolic process GO:0045981 230 0.018
regulation of secretion GO:0051046 194 0.017
rho protein signal transduction GO:0007266 26 0.017
positive regulation of nucleotide catabolic process GO:0030813 185 0.017
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.017
inorganic ion transmembrane transport GO:0098660 231 0.017
growth GO:0040007 202 0.017
glycerolipid metabolic process GO:0046486 107 0.017
regulation of purine nucleotide metabolic process GO:1900542 264 0.017
oocyte development GO:0048599 1 0.017
cellular ion homeostasis GO:0006873 168 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
cell fate determination GO:0001709 3 0.017
positive regulation of mapk cascade GO:0043410 190 0.017
myeloid cell differentiation GO:0030099 117 0.017
negative regulation of cell migration GO:0030336 102 0.017
oocyte differentiation GO:0009994 2 0.017
positive regulation of cell migration GO:0030335 172 0.017
cell projection organization GO:0030030 252 0.017
neurogenesis GO:0022008 169 0.017
response to cytokine GO:0034097 232 0.017
regulation of cell cycle process GO:0010564 266 0.016
neuromuscular junction development GO:0007528 3 0.016
response to external biotic stimulus GO:0043207 261 0.016
regulation of protein maturation GO:1903317 150 0.016
cellular modified amino acid metabolic process GO:0006575 64 0.016
secretion by cell GO:0032940 226 0.016
divalent metal ion transport GO:0070838 152 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
response to bacterium GO:0009617 144 0.016
regulation of immune response GO:0050776 201 0.016
sulfur compound metabolic process GO:0006790 101 0.016
glycosyl compound catabolic process GO:1901658 413 0.016
cellular response to cytokine stimulus GO:0071345 181 0.016
regulation of intracellular transport GO:0032386 195 0.016
chemotaxis GO:0006935 157 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.016
positive regulation of nucleoside metabolic process GO:0045979 186 0.016
carbohydrate derivative biosynthetic process GO:1901137 207 0.016
carboxylic acid transport GO:0046942 63 0.016
regulation of nucleotide metabolic process GO:0006140 269 0.016
organelle assembly GO:0070925 176 0.016
motor neuron axon guidance GO:0008045 2 0.016
interspecies interaction between organisms GO:0044419 156 0.016
positive regulation of kinase activity GO:0033674 204 0.016
positive regulation of immune system process GO:0002684 283 0.015
9 cis retinoic acid metabolic process GO:0042905 1 0.015
erk1 and erk2 cascade GO:0070371 104 0.015
cardiac muscle cell contraction GO:0086003 4 0.015
regulation of body fluid levels GO:0050878 99 0.015
gtp metabolic process GO:0046039 239 0.015
negative regulation of protein maturation GO:1903318 142 0.015
negative regulation of cellular amine metabolic process GO:0033239 3 0.015
regulation of nucleoside metabolic process GO:0009118 209 0.015
negative regulation of cell cycle GO:0045786 193 0.015
morphogenesis of a polarized epithelium GO:0001738 3 0.015
positive regulation of organelle organization GO:0010638 195 0.015
regulation of gtpase activity GO:0043087 180 0.015
positive regulation of cell motility GO:2000147 177 0.015
inner ear morphogenesis GO:0042472 4 0.015
behavior GO:0007610 112 0.015
spermatid development GO:0007286 4 0.015
cellular amide metabolic process GO:0043603 69 0.015
positive regulation of cytokine production GO:0001819 167 0.015
organ morphogenesis GO:0009887 147 0.015
negative regulation of immune system process GO:0002683 136 0.015
viral life cycle GO:0019058 132 0.015
regulation of cell development GO:0060284 161 0.015
guanosine containing compound catabolic process GO:1901069 239 0.015
cellular metal ion homeostasis GO:0006875 146 0.015
leukocyte migration GO:0050900 107 0.015
ketone catabolic process GO:0042182 3 0.015
Mouse
regulation of cell morphogenesis GO:0022604 153 0.015
metencephalon development GO:0022037 2 0.015
regulation of endopeptidase activity GO:0052548 170 0.015
cation transmembrane transport GO:0098655 238 0.015
immune system development GO:0002520 195 0.015
embryonic viscerocranium morphogenesis GO:0048703 1 0.015
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.015
tissue morphogenesis GO:0048729 96 0.014
membrane organization GO:0061024 292 0.014
dephosphorylation GO:0016311 209 0.014
syncytium formation by plasma membrane fusion GO:0000768 2 0.014
mitotic cell cycle process GO:1903047 286 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.014
nucleotide catabolic process GO:0009166 408 0.014
cellular response to dna damage stimulus GO:0006974 379 0.014

AKR1C1 disease predictions

Disease DO term ID Size Probability Func Analog Org
chromosomal disease DOID:0080014 16 0.387
Human
gonadal dysgenesis DOID:14447 8 0.387
Human
46 xy gonadal dysgenesis DOID:14448 8 0.177
Human
disease of metabolism DOID:0014667 295 0.070
Human
inherited metabolic disorder DOID:655 242 0.027
Human
sensory system disease DOID:0050155 203 0.021
eye and adnexa disease DOID:1492 150 0.021
nervous system disease DOID:863 431 0.021
central nervous system disease DOID:331 186 0.019
musculoskeletal system disease DOID:17 223 0.019
cancer DOID:162 167 0.018
disease of cellular proliferation DOID:14566 174 0.018
immune system disease DOID:2914 155 0.018
hematopoietic system disease DOID:74 100 0.016
organ system cancer DOID:0050686 164 0.016
eye disease DOID:5614 149 0.015