|
|
very low density lipoprotein particle remodeling
|
GO:0034372 |
10 |
0.998
|
|
|
|
protein lipid complex remodeling
|
GO:0034368 |
16 |
0.988
|
|
|
|
macromolecular complex remodeling
|
GO:0034367 |
16 |
0.963
|
|
|
|
plasma lipoprotein particle remodeling
|
GO:0034369 |
16 |
0.963
|
|
|
|
sterol esterification
|
GO:0034434 |
10 |
0.948
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
4 |
0.934
|
|
|
|
positive regulation of cholesterol esterification
|
GO:0010873 |
6 |
0.929
|
|
|
|
high density lipoprotein particle remodeling
|
GO:0034375 |
8 |
0.913
|
|
|
|
very low density lipoprotein particle clearance
|
GO:0034447 |
6 |
0.908
|
|
|
|
cell adhesion molecule production
|
GO:0060352 |
3 |
0.907
|
|
|
|
reverse cholesterol transport
|
GO:0043691 |
8 |
0.845
|
|
|
|
neurotransmitter gated ion channel clustering
|
GO:0072578 |
1 |
0.839
|
|
|
|
presynaptic membrane organization
|
GO:0097090 |
3 |
0.821
|
|
|
|
plasma lipoprotein particle organization
|
GO:0071827 |
22 |
0.819
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.812
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.806
|
|
|
|
sterol transport
|
GO:0015918 |
39 |
0.804
|
|
|
|
dendritic spine maintenance
|
GO:0097062 |
1 |
0.799
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.786
|
|
|
|
cholesterol homeostasis
|
GO:0042632 |
28 |
0.782
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.781
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.762
|
Human |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.761
|
|
|
|
regulation of cholesterol metabolic process
|
GO:0090181 |
4 |
0.759
|
|
|
|
regulation of tube size
|
GO:0035150 |
18 |
0.731
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.730
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.729
|
|
|
|
negative regulation of interleukin 1 beta secretion
|
GO:0050713 |
2 |
0.725
|
|
|
|
protein lipid complex subunit organization
|
GO:0071825 |
24 |
0.718
|
|
|
|
positive regulation of cgmp metabolic process
|
GO:0030825 |
5 |
0.698
|
|
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
38 |
0.684
|
|
|
|
positive regulation of cgmp biosynthetic process
|
GO:0030828 |
3 |
0.677
|
|
|
|
lipid modification
|
GO:0030258 |
84 |
0.676
|
|
|
|
positive regulation of rho protein signal transduction
|
GO:0035025 |
4 |
0.674
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.667
|
|
|
|
triglyceride rich lipoprotein particle remodeling
|
GO:0034370 |
10 |
0.666
|
|
|
|
low density lipoprotein particle remodeling
|
GO:0034374 |
6 |
0.663
|
|
|
|
chylomicron remnant clearance
|
GO:0034382 |
4 |
0.662
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.661
|
|
|
|
steroid catabolic process
|
GO:0006706 |
10 |
0.655
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.641
|
|
|
|
negative regulation of cell adhesion molecule production
|
GO:0060354 |
1 |
0.638
|
|
|
|
negative regulation of sterol transport
|
GO:0032372 |
8 |
0.637
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.627
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.626
|
Human |
|
|
regulation of receptor catabolic process
|
GO:2000644 |
2 |
0.623
|
|
|
|
negative regulation of wound healing
|
GO:0061045 |
25 |
0.622
|
Human |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.617
|
|
|
|
negative regulation of interleukin 1 secretion
|
GO:0050711 |
4 |
0.611
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.610
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.603
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.601
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
18 |
0.601
|
|
|
|
cholesterol esterification
|
GO:0034435 |
10 |
0.600
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.578
|
Human |
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.572
|
|
|
|
regulation of cholesterol esterification
|
GO:0010872 |
7 |
0.570
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.564
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.560
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.556
|
|
|
|
vasodilation
|
GO:0042311 |
4 |
0.555
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.554
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.546
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.542
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
51 |
0.536
|
Human |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.535
|
Human |
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.521
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.516
|
|
|
|
cholesterol transport
|
GO:0030301 |
39 |
0.507
|
|
|
|
sterol catabolic process
|
GO:0016127 |
3 |
0.505
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.503
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.503
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.498
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.495
|
|
|
|
beta amyloid clearance
|
GO:0097242 |
5 |
0.492
|
|
|
|
phosphatidylcholine metabolic process
|
GO:0046470 |
19 |
0.490
|
|
|
|
negative regulation of cholesterol transport
|
GO:0032375 |
8 |
0.489
|
|
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
29 |
0.488
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.487
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.486
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.473
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.468
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.468
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.467
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.456
|
|
|
|
cellular biogenic amine metabolic process
|
GO:0006576 |
34 |
0.453
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.450
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.446
|
Human |
|
|
sterol homeostasis
|
GO:0055092 |
28 |
0.438
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.437
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.437
|
Human |
|
|
postsynaptic membrane organization
|
GO:0001941 |
2 |
0.432
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.422
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.413
|
Human |
|
|
negative regulation of cytokine mediated signaling pathway
|
GO:0001960 |
22 |
0.412
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.412
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.410
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.409
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.408
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.402
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.402
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.395
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.395
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.392
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.380
|
|
|
|
n methyl d aspartate receptor clustering
|
GO:0097114 |
1 |
0.378
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.374
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.373
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.368
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.366
|
Human |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.357
|
Human |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.349
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.348
|
|
|
|
phospholipid efflux
|
GO:0033700 |
11 |
0.347
|
|
|
|
high density lipoprotein particle assembly
|
GO:0034380 |
5 |
0.345
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.342
|
Human |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.341
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.332
|
|
|
|
regulation of plasma lipoprotein particle levels
|
GO:0097006 |
32 |
0.332
|
|
|
|
ethanolamine containing compound metabolic process
|
GO:0042439 |
26 |
0.328
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.322
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.317
|
|
|
|
positive regulation of beta amyloid formation
|
GO:1902004 |
4 |
0.316
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.315
|
|
|
|
protein activation cascade
|
GO:0072376 |
22 |
0.312
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.311
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.308
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.308
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.307
|
|
|
|
negative regulation of dendritic spine development
|
GO:0061000 |
1 |
0.305
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.304
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.303
|
Human |
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.298
|
Human |
|
|
phospholipid biosynthetic process
|
GO:0008654 |
44 |
0.292
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
22 |
0.292
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.290
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.290
|
|
|
|
plasma lipoprotein particle clearance
|
GO:0034381 |
16 |
0.286
|
|
|
|
cholesterol catabolic process
|
GO:0006707 |
3 |
0.284
|
|
|
|
regulation of low density lipoprotein particle receptor catabolic process
|
GO:0032803 |
2 |
0.284
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.282
|
|
|
|
regulation of interleukin 1 beta secretion
|
GO:0050706 |
12 |
0.280
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
38 |
0.280
|
|
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
30 |
0.279
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.276
|
|
|
|
negative regulation of blood vessel endothelial cell migration
|
GO:0043537 |
16 |
0.274
|
|
|
|
regulation of cytokine secretion involved in immune response
|
GO:0002739 |
7 |
0.272
|
|
|
|
positive regulation of dendritic spine development
|
GO:0060999 |
2 |
0.271
|
|
|
|
negative regulation of tumor necrosis factor mediated signaling pathway
|
GO:0010804 |
7 |
0.270
|
|
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
25 |
0.270
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.269
|
Human |
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.269
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.268
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.264
|
|
|
|
negative regulation of hemostasis
|
GO:1900047 |
22 |
0.260
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
50 |
0.259
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.256
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.254
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.254
|
|
|
|
negative regulation of cytokine production involved in immune response
|
GO:0002719 |
13 |
0.253
|
|
|
|
negative regulation of blood coagulation
|
GO:0030195 |
22 |
0.247
|
|
|
|
lipoprotein biosynthetic process
|
GO:0042158 |
33 |
0.246
|
|
|
|
regulation of cell adhesion molecule production
|
GO:0060353 |
1 |
0.245
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.237
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.236
|
|
|
|
triglyceride metabolic process
|
GO:0006641 |
23 |
0.235
|
Human |
|
|
vascular process in circulatory system
|
GO:0003018 |
29 |
0.235
|
|
|
|
cgmp mediated signaling
|
GO:0019934 |
5 |
0.234
|
|
|
|
negative regulation of hydrogen peroxide metabolic process
|
GO:0010727 |
3 |
0.234
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.229
|
|
|
|
triglyceride rich lipoprotein particle clearance
|
GO:0071830 |
4 |
0.226
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.226
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.226
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
42 |
0.225
|
|
|
|
membrane protein ectodomain proteolysis
|
GO:0006509 |
33 |
0.225
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.224
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.223
|
Human |
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.218
|
|
|
|
phenylpropanoid metabolic process
|
GO:0009698 |
3 |
0.217
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.216
|
|
|
|
negative regulation of cellular amide metabolic process
|
GO:0034249 |
3 |
0.214
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.214
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.213
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.210
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.208
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.207
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.206
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.206
|
|
|
|
regulation of heterotypic cell cell adhesion
|
GO:0034114 |
14 |
0.203
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.203
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
50 |
0.202
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.202
|
Human |
|
|
regulation of cdc42 protein signal transduction
|
GO:0032489 |
14 |
0.202
|
|
|
|
negative regulation of amyloid precursor protein catabolic process
|
GO:1902992 |
4 |
0.201
|
|
|
|
cyclic nucleotide mediated signaling
|
GO:0019935 |
26 |
0.197
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
0.197
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.197
|
|
|
|
organic hydroxy compound catabolic process
|
GO:1901616 |
22 |
0.195
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.193
|
Human |
|
|
cytokine secretion involved in immune response
|
GO:0002374 |
7 |
0.192
|
|
|
|
interleukin 1 beta secretion
|
GO:0050702 |
15 |
0.190
|
|
|
|
membrane protein proteolysis
|
GO:0033619 |
38 |
0.190
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.189
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.186
|
Human |
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
38 |
0.186
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.186
|
Human |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.184
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.183
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.182
|
Human |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.182
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.181
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.180
|
Human |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.178
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.178
|
|
|
|
system process
|
GO:0003008 |
349 |
0.177
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.176
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.175
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.174
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.171
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.170
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.169
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.169
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.169
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.167
|
|
|
|
regulation of interleukin 1 secretion
|
GO:0050704 |
14 |
0.167
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.167
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.167
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.166
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.166
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.163
|
Human |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.163
|
|
|
|
heterotypic cell cell adhesion
|
GO:0034113 |
28 |
0.162
|
|
|
|
renal water homeostasis
|
GO:0003091 |
4 |
0.161
|
|
|
|
phospholipid transport
|
GO:0015914 |
23 |
0.160
|
|
|
|
acylglycerol metabolic process
|
GO:0006639 |
27 |
0.159
|
Human |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.159
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.158
|
|
|
|
platelet activation
|
GO:0030168 |
44 |
0.158
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.158
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.157
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
27 |
0.157
|
|
|
|
negative regulation of phospholipid transport
|
GO:2001139 |
1 |
0.156
|
|
|
|
lipoprotein metabolic process
|
GO:0042157 |
42 |
0.156
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.156
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.156
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.153
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.152
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.151
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.151
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.150
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.150
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.149
|
|
|
|
lipid homeostasis
|
GO:0055088 |
39 |
0.149
|
|
|
|
nitric oxide mediated signal transduction
|
GO:0007263 |
7 |
0.147
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.144
|
|
|
|
cholesterol metabolic process
|
GO:0008203 |
28 |
0.144
|
|
|
|
sterol metabolic process
|
GO:0016125 |
28 |
0.143
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.142
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.137
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.137
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.136
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.136
|
Human |
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.134
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.132
|
|
|
|
prostate gland morphogenesis
|
GO:0060512 |
1 |
0.132
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.132
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.131
|
|
|
|
interleukin 1 beta production
|
GO:0032611 |
22 |
0.130
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.130
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.130
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.129
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.129
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.128
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
47 |
0.128
|
Human |
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.128
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.128
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.127
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.127
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.127
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.126
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.125
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.125
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.123
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.123
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.122
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.121
|
Human |
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
3 |
0.121
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
38 |
0.120
|
|
|
|
cgmp metabolic process
|
GO:0046068 |
19 |
0.119
|
|
|
|
response to increased oxygen levels
|
GO:0036296 |
4 |
0.119
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.118
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.117
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.117
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.116
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.116
|
|
|
|
regulation of very low density lipoprotein particle remodeling
|
GO:0010901 |
4 |
0.115
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.114
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.114
|
|
|
|
negative regulation of lipid transport
|
GO:0032369 |
18 |
0.114
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.112
|
Human |
|
|
regulation of interleukin 1 production
|
GO:0032652 |
21 |
0.112
|
|
|
|
positive regulation of oxidoreductase activity
|
GO:0051353 |
26 |
0.111
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.111
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.111
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.111
|
|
|
|
regulation of cgmp biosynthetic process
|
GO:0030826 |
4 |
0.110
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.110
|
Human |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.110
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.109
|
|
|
|
long chain fatty acid transport
|
GO:0015909 |
18 |
0.109
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.108
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.108
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.107
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.106
|
|
|
|
negative regulation of dendrite development
|
GO:2000171 |
5 |
0.105
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.105
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.104
|
|
|
|
high density lipoprotein particle clearance
|
GO:0034384 |
6 |
0.104
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.104
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.103
|
|
|
|
glycerophospholipid biosynthetic process
|
GO:0046474 |
40 |
0.103
|
|
|
|
negative regulation of cell projection organization
|
GO:0031345 |
22 |
0.102
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.102
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.101
|
|
|
|
regulation of actin filament bundle assembly
|
GO:0032231 |
36 |
0.101
|
|
|
|
negative regulation of complement activation lectin pathway
|
GO:0001869 |
2 |
0.101
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
69 |
0.099
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.099
|
Human |
|
|
interleukin 1 secretion
|
GO:0050701 |
18 |
0.098
|
|
|
|
regulation of interleukin 1 beta production
|
GO:0032651 |
18 |
0.098
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.097
|
Human |
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.096
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.096
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.095
|
|
|
|
trabecula morphogenesis
|
GO:0061383 |
2 |
0.095
|
|
|
|
positive regulation of amyloid precursor protein catabolic process
|
GO:1902993 |
4 |
0.095
|
|
|
|
low density lipoprotein particle receptor catabolic process
|
GO:0032802 |
3 |
0.095
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.095
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.094
|
Human |
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.093
|
Human |
|
|
negative regulation of beta amyloid formation
|
GO:1902430 |
3 |
0.093
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.093
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.092
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.091
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.091
|
|
|
|
response to activity
|
GO:0014823 |
0 |
0.091
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.091
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.090
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.090
|
Human |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.090
|
|
|
|
peptide metabolic process
|
GO:0006518 |
51 |
0.090
|
|
|
|
monocarboxylic acid transport
|
GO:0015718 |
32 |
0.089
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.089
|
|
|
|
positive regulation of phospholipid transport
|
GO:2001140 |
4 |
0.088
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.088
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.087
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.086
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.086
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.085
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.085
|
|
|
|
regulation of cholesterol biosynthetic process
|
GO:0045540 |
3 |
0.085
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.085
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.084
|
|
|
|
regulation of tumor necrosis factor mediated signaling pathway
|
GO:0010803 |
12 |
0.084
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.084
|
|
|
|
negative regulation of neuron projection development
|
GO:0010977 |
15 |
0.084
|
|
|
|
naphthalene metabolic process
|
GO:0018931 |
1 |
0.084
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.083
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.083
|
Human |
|
|
regulation of oxidoreductase activity
|
GO:0051341 |
43 |
0.083
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.082
|
|
|
|
alcohol biosynthetic process
|
GO:0046165 |
52 |
0.082
|
|
|
|
regulation of membrane protein ectodomain proteolysis
|
GO:0051043 |
17 |
0.082
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.082
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.082
|
|
|
|
phospholipid homeostasis
|
GO:0055091 |
6 |
0.082
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.082
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.081
|
|
|
|
peptidyl methionine modification
|
GO:0018206 |
5 |
0.081
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.081
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.081
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.081
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.080
|
Human |
|
|
negative regulation of response to cytokine stimulus
|
GO:0060761 |
25 |
0.080
|
|
|
|
interleukin 1 production
|
GO:0032612 |
26 |
0.080
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.079
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.078
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.078
|
|
|
|
negative chemotaxis
|
GO:0050919 |
11 |
0.077
|
|
|
|
regulation of coagulation
|
GO:0050818 |
44 |
0.077
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.077
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.077
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.077
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.077
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
25 |
0.077
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.076
|
|
|
|
anion homeostasis
|
GO:0055081 |
18 |
0.075
|
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
38 |
0.075
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.074
|
|
|
|
positive regulation of lipid biosynthetic process
|
GO:0046889 |
22 |
0.074
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.074
|
Human |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.074
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.073
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.073
|
|
|
|
sterol transmembrane transport
|
GO:0035382 |
4 |
0.072
|
|
|
|
small molecule catabolic process
|
GO:0044282 |
92 |
0.072
|
|
|
|
regulation of beta amyloid clearance
|
GO:1900221 |
5 |
0.072
|
|
|
|
receptor catabolic process
|
GO:0032801 |
11 |
0.072
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.071
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.071
|
|
|
|
organic anion transport
|
GO:0015711 |
103 |
0.071
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.071
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.070
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
26 |
0.069
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.069
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.069
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.068
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.068
|
|
|
|
negative regulation of heterotypic cell cell adhesion
|
GO:0034115 |
6 |
0.068
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.068
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
33 |
0.068
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.068
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.067
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.067
|
Human |
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.067
|
Human |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.067
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.067
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.066
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.066
|
Human |
|
|
smooth muscle cell proliferation
|
GO:0048659 |
28 |
0.066
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.066
|
|
|
|
regulation of cgmp metabolic process
|
GO:0030823 |
9 |
0.066
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.066
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.065
|
|
|
|
regulation of sterol transport
|
GO:0032371 |
21 |
0.065
|
|
|
|
organophosphate ester transport
|
GO:0015748 |
32 |
0.065
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
21 |
0.065
|
|
|
|
prostate gland development
|
GO:0030850 |
3 |
0.065
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.064
|
|
|
|
regulation of cell cell adhesion involved in gastrulation
|
GO:0070587 |
6 |
0.064
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.063
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.063
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.063
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.063
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.062
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
38 |
0.062
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.062
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.062
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.062
|
|
|
|
glycerophospholipid catabolic process
|
GO:0046475 |
6 |
0.062
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.062
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.062
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.062
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.061
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.060
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.060
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.060
|
|
|
|
regulation of cholesterol efflux
|
GO:0010874 |
11 |
0.060
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.059
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.059
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.059
|
|
|
|
positive regulation of small gtpase mediated signal transduction
|
GO:0051057 |
12 |
0.058
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.058
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.057
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.057
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.057
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.056
|
Human |
|
|
negative regulation of platelet activation
|
GO:0010544 |
7 |
0.056
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.056
|
|
|
|
negative regulation of angiogenesis
|
GO:0016525 |
39 |
0.055
|
|
|
|
positive regulation of cholesterol efflux
|
GO:0010875 |
8 |
0.055
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.055
|
|
|
|
blood vessel maturation
|
GO:0001955 |
1 |
0.055
|
|
|
|
complement activation
|
GO:0006956 |
19 |
0.054
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.054
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.054
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.054
|
|
|
|
positive regulation of membrane protein ectodomain proteolysis
|
GO:0051044 |
13 |
0.053
|
|
|
|
negative regulation of cell cell adhesion
|
GO:0022408 |
27 |
0.053
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.053
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.053
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.053
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.052
|
Human |
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.052
|
|
