Homo sapiens

7 known processes

AARS

alanyl-tRNA synthetase

(Aliases: CMT2N)

AARS biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
amino acid activation GO:0043038 12 1.000
Mouse Rat
trna aminoacylation for protein translation GO:0006418 8 1.000
Mouse Rat
trna aminoacylation GO:0043039 12 0.982
Mouse Rat
cellular amino acid metabolic process GO:0006520 116 0.897
Mouse Rat
alpha amino acid metabolic process GO:1901605 72 0.831
cellular amino acid biosynthetic process GO:0008652 30 0.768
ncrna metabolic process GO:0034660 108 0.736
Mouse Rat
serine family amino acid metabolic process GO:0009069 12 0.691
one carbon metabolic process GO:0006730 1 0.593
carboxylic acid biosynthetic process GO:0046394 97 0.574
small molecule biosynthetic process GO:0044283 157 0.410
organonitrogen compound biosynthetic process GO:1901566 200 0.388
translation GO:0006412 132 0.369
Mouse Rat
post embryonic development GO:0009791 2 0.366
Worm
l serine metabolic process GO:0006563 5 0.332
cellular amino acid catabolic process GO:0009063 31 0.326
proline transport GO:0015824 4 0.310
dicarboxylic acid metabolic process GO:0043648 29 0.283
aspartate family amino acid catabolic process GO:0009068 5 0.281
glutamine family amino acid metabolic process GO:0009064 17 0.281
mitochondrial rna metabolic process GO:0000959 15 0.266
organic acid biosynthetic process GO:0016053 97 0.246
coenzyme metabolic process GO:0006732 65 0.243
angiogenesis GO:0001525 147 0.219
modified amino acid transport GO:0072337 11 0.209
cation transmembrane transport GO:0098655 238 0.205
chloride transmembrane transport GO:1902476 38 0.168
patterning of blood vessels GO:0001569 2 0.155
vesicle mediated transport GO:0016192 371 0.151
glycine metabolic process GO:0006544 4 0.143
regulation of mitotic cell cycle GO:0007346 189 0.139
alanine transport GO:0032328 3 0.131
oogenesis GO:0048477 2 0.120
Worm
nucleoside phosphate biosynthetic process GO:1901293 109 0.117
dicarboxylic acid catabolic process GO:0043649 9 0.108
alpha amino acid catabolic process GO:1901606 26 0.108
oxaloacetate metabolic process GO:0006107 1 0.105
trna metabolic process GO:0006399 35 0.102
Mouse Rat
water soluble vitamin metabolic process GO:0006767 6 0.100
embryo development GO:0009790 123 0.096
Worm
mitotic cell cycle GO:0000278 326 0.095
aspartate family amino acid biosynthetic process GO:0009067 6 0.091
single organism carbohydrate metabolic process GO:0044723 193 0.090
response to radiation GO:0009314 151 0.090
organic anion transport GO:0015711 103 0.090
response to cytokine GO:0034097 232 0.085
response to abiotic stimulus GO:0009628 336 0.083
dicarboxylic acid biosynthetic process GO:0043650 4 0.080
cellular response to cytokine stimulus GO:0071345 181 0.077
cellular response to endogenous stimulus GO:0071495 336 0.075
purine nucleobase biosynthetic process GO:0009113 3 0.074
female gamete generation GO:0007292 2 0.074
Worm
cellular protein complex assembly GO:0043623 188 0.072
response to mechanical stimulus GO:0009612 51 0.071
negative regulation of apoptotic process GO:0043066 316 0.068
Mouse
segmentation GO:0035282 4 0.065
positive regulation of cell cycle GO:0045787 140 0.064
carbohydrate biosynthetic process GO:0016051 42 0.062
serine family amino acid catabolic process GO:0009071 5 0.062
response to amino acid GO:0043200 14 0.059
Mouse
dna templated transcription termination GO:0006353 3 0.058
amide biosynthetic process GO:0043604 15 0.058
chemical homeostasis GO:0048878 306 0.057
response to insulin GO:0032868 45 0.056
cell projection organization GO:0030030 252 0.052
response to peptide GO:1901652 65 0.052
maintenance of location GO:0051235 112 0.052
nucleobase biosynthetic process GO:0046112 4 0.052
response to oxygen containing compound GO:1901700 369 0.049
Mouse
sulfur amino acid transport GO:0000101 2 0.048
positive regulation of mitotic cell cycle GO:0045931 60 0.047
response to hypoxia GO:0001666 96 0.045
cellular response to hormone stimulus GO:0032870 125 0.045
nucleotide biosynthetic process GO:0009165 109 0.044
purine containing compound biosynthetic process GO:0072522 88 0.044
organophosphate biosynthetic process GO:0090407 163 0.044
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.043
regulation of cell cycle GO:0051726 393 0.042
oocyte development GO:0048599 1 0.041
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.041
response to hormone GO:0009725 175 0.040
oocyte differentiation GO:0009994 2 0.040
response to nitrogen compound GO:1901698 184 0.040
Mouse
monocarboxylic acid metabolic process GO:0032787 185 0.039
blastoderm segmentation GO:0007350 2 0.039
regulation of anatomical structure morphogenesis GO:0022603 286 0.039
positive regulation of organelle organization GO:0010638 195 0.039
neurogenesis GO:0022008 169 0.037
cation transport GO:0006812 331 0.036
hematopoietic or lymphoid organ development GO:0048534 186 0.036
blood vessel development GO:0001568 172 0.035
cellular response to external stimulus GO:0071496 111 0.035
negative regulation of programmed cell death GO:0043069 321 0.034
Mouse
multicellular organismal aging GO:0010259 3 0.034
response to peptide hormone GO:0043434 61 0.033
inorganic ion transmembrane transport GO:0098660 231 0.033
vasculature development GO:0001944 181 0.032
anterior posterior axis specification GO:0009948 2 0.031
system process GO:0003008 349 0.030
Mouse
cellular macromolecular complex assembly GO:0034622 324 0.030
amino acid transmembrane transport GO:0003333 20 0.030
response to decreased oxygen levels GO:0036293 96 0.030
l alanine transport GO:0015808 3 0.029
cellular protein catabolic process GO:0044257 261 0.029
mitochondrion organization GO:0007005 156 0.029
positive regulation of hydrolase activity GO:0051345 331 0.029
nucleobase metabolic process GO:0009112 8 0.029
cellular amine metabolic process GO:0044106 41 0.028
response to endoplasmic reticulum stress GO:0034976 49 0.028
Mouse
organic hydroxy compound metabolic process GO:1901615 147 0.027
transmembrane transport GO:0055085 399 0.027
negative regulation of cell proliferation GO:0008285 228 0.026
tripartite regional subdivision GO:0007351 2 0.026
glycerol metabolic process GO:0006071 4 0.026
aspartate metabolic process GO:0006531 4 0.026
anterior posterior axis specification embryo GO:0008595 2 0.025
negative regulation of cell death GO:0060548 345 0.025
Mouse
proteasomal protein catabolic process GO:0010498 176 0.024
amine metabolic process GO:0009308 44 0.024
alpha amino acid biosynthetic process GO:1901607 23 0.023
neurological system process GO:0050877 163 0.023
Mouse
glutamate metabolic process GO:0006536 10 0.023
regulation of cellular amine metabolic process GO:0033238 11 0.023
reproduction GO:0000003 63 0.022
Worm
negative regulation of phosphate metabolic process GO:0045936 267 0.022
carbohydrate metabolic process GO:0005975 207 0.022
positive regulation of cellular catabolic process GO:0031331 284 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.022
negative regulation of catalytic activity GO:0043086 335 0.022
regulation of proteolysis GO:0030162 293 0.021
cellular macromolecule catabolic process GO:0044265 380 0.021
purine nucleobase metabolic process GO:0006144 5 0.021
hemopoiesis GO:0030097 180 0.021
chloride transport GO:0006821 41 0.021
modification dependent protein catabolic process GO:0019941 209 0.021
blood vessel morphogenesis GO:0048514 162 0.021
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.021
embryo development ending in birth or egg hatching GO:0009792 34 0.021
Worm
carbohydrate derivative biosynthetic process GO:1901137 207 0.020
cellular response to starvation GO:0009267 58 0.020
vitamin metabolic process GO:0006766 26 0.020
intracellular mrna localization GO:0008298 1 0.020
endocytosis GO:0006897 159 0.020
regulation of cellular amino acid metabolic process GO:0006521 6 0.020
response to organic cyclic compound GO:0014070 204 0.020
organic acid catabolic process GO:0016054 71 0.020
osteoblast differentiation GO:0001649 92 0.020
metal ion transport GO:0030001 272 0.020
anatomical structure formation involved in morphogenesis GO:0048646 284 0.020
cellular response to extracellular stimulus GO:0031668 72 0.020
tube morphogenesis GO:0035239 95 0.020
small molecule catabolic process GO:0044282 92 0.019
pigment biosynthetic process GO:0046148 10 0.019
ion homeostasis GO:0050801 230 0.019
pattern specification process GO:0007389 43 0.019
response to starvation GO:0042594 59 0.018
protein modification by small protein conjugation GO:0032446 342 0.018
sulfur compound metabolic process GO:0006790 101 0.018
response to lipid GO:0033993 206 0.018
cell development GO:0048468 328 0.018
Worm
protein folding GO:0006457 38 0.018
Mouse
myeloid cell differentiation GO:0030099 117 0.018
protein catabolic process GO:0030163 325 0.018
single organism cellular localization GO:1902580 332 0.018
branching morphogenesis of an epithelial tube GO:0048754 19 0.018
circulatory system development GO:0072359 262 0.017
immune response GO:0006955 307 0.017
nervous system development GO:0007399 293 0.017
Mouse
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.017
protein ubiquitination GO:0016567 314 0.017
protein polymerization GO:0051258 71 0.017
regulation of protein polymerization GO:0032271 63 0.017
rhythmic behavior GO:0007622 2 0.017
cell cycle phase transition GO:0044770 173 0.017
mitotic cell cycle process GO:1903047 286 0.016
regulation of protein complex assembly GO:0043254 147 0.016
regulation of response to external stimulus GO:0032101 222 0.016
gamma aminobutyric acid metabolic process GO:0009448 1 0.016
cellular amide metabolic process GO:0043603 69 0.016
cellular response to oxygen containing compound GO:1901701 276 0.016
negative regulation of hydrolase activity GO:0051346 182 0.016
d aspartate transport GO:0070777 3 0.016
lung cell differentiation GO:0060479 1 0.016
tube development GO:0035295 125 0.016
ribonucleoprotein complex biogenesis GO:0022613 116 0.016
positive regulation of cellular component organization GO:0051130 376 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.016
purine nucleoside triphosphate catabolic process GO:0009146 392 0.015
peptidyl tyrosine modification GO:0018212 170 0.015
microtubule polymerization GO:0046785 18 0.015
tor signaling GO:0031929 39 0.015
protein tetramerization GO:0051262 47 0.015
small gtpase mediated signal transduction GO:0007264 78 0.015
carboxylic acid catabolic process GO:0046395 71 0.015
innate immune response GO:0045087 178 0.014
immune system development GO:0002520 195 0.014
positive regulation of catabolic process GO:0009896 310 0.014
response to organonitrogen compound GO:0010243 156 0.014
Mouse
regulation of purine nucleotide catabolic process GO:0033121 205 0.014
regulation of dna metabolic process GO:0051052 153 0.014
actin mediated cell contraction GO:0070252 12 0.014
regulation of endopeptidase activity GO:0052548 170 0.014
memory GO:0007613 3 0.014
cell morphogenesis GO:0000902 296 0.014
regulation of cellular ketone metabolic process GO:0010565 50 0.014
response to oxygen levels GO:0070482 100 0.014
regulation of transferase activity GO:0051338 355 0.014
positive regulation of protein catabolic process GO:0045732 75 0.014
protein refolding GO:0042026 14 0.014
ion transmembrane transport GO:0034220 338 0.014
ribonucleoside triphosphate metabolic process GO:0009199 412 0.014
mitotic cell cycle phase transition GO:0044772 162 0.013
ras protein signal transduction GO:0007265 73 0.013
regulation of secretion GO:0051046 194 0.013
atp metabolic process GO:0046034 176 0.013
mitochondrial translation GO:0032543 17 0.013
l serine catabolic process GO:0006565 3 0.013
cellular response to glucose starvation GO:0042149 8 0.013
neurotransmitter secretion GO:0007269 4 0.013
response to steroid hormone GO:0048545 80 0.013
cellular modified amino acid metabolic process GO:0006575 64 0.013
generation of neurons GO:0048699 152 0.013
cellular response to dna damage stimulus GO:0006974 379 0.013
microtubule based process GO:0007017 210 0.012
purine ribonucleotide catabolic process GO:0009154 404 0.012
positive regulation of protein complex assembly GO:0031334 86 0.012
regeneration GO:0031099 4 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
response to light stimulus GO:0009416 87 0.012
associative learning GO:0008306 1 0.012
alcohol metabolic process GO:0006066 114 0.012
purine ribonucleoside metabolic process GO:0046128 437 0.012
d aspartate import GO:0070779 3 0.012
lipid homeostasis GO:0055088 39 0.012
protein processing GO:0016485 226 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
inorganic anion transmembrane transport GO:0098661 47 0.012
actin filament based movement GO:0030048 17 0.012
epithelium development GO:0060429 227 0.012
Mouse
protein maturation GO:0051604 233 0.012
ribonucleotide biosynthetic process GO:0009260 81 0.012
tissue morphogenesis GO:0048729 96 0.011
ribose phosphate biosynthetic process GO:0046390 82 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.011
multi organism reproductive process GO:0044703 54 0.011
Worm
regulation of actin filament length GO:0030832 56 0.011
regulation of hormone levels GO:0010817 125 0.011
receptor mediated endocytosis GO:0006898 84 0.011
embryonic eye morphogenesis GO:0048048 2 0.011
ossification GO:0001503 121 0.011
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
negative regulation of developmental process GO:0051093 247 0.011
regulation of microtubule based process GO:0032886 74 0.011
negative regulation of cellular protein metabolic process GO:0032269 353 0.011
cardiovascular system development GO:0072358 262 0.011
organelle assembly GO:0070925 176 0.011
regulation of cellular protein catabolic process GO:1903362 96 0.011
peptidyl serine phosphorylation GO:0018105 101 0.011
regulation of peptidyl serine phosphorylation GO:0033135 50 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.011
actin filament based process GO:0030029 224 0.011
regulation of cell division GO:0051302 116 0.011
regulation of protein processing GO:0070613 150 0.011
response to sucrose GO:0009744 1 0.011
gtp catabolic process GO:0006184 237 0.011
regulation of circadian sleep wake cycle sleep GO:0045187 2 0.010
arginine transport GO:0015809 2 0.010
regulation of viral process GO:0050792 103 0.010
cell adhesion GO:0007155 325 0.010
cellular response to nutrient levels GO:0031669 69 0.010
eye photoreceptor cell differentiation GO:0001754 2 0.010
metencephalon development GO:0022037 2 0.010
Mouse
response to interferon gamma GO:0034341 39 0.010
circadian behavior GO:0048512 2 0.010
negative regulation of mitotic cell cycle GO:0045930 102 0.010
regulation of nucleotide metabolic process GO:0006140 269 0.010
t cell differentiation in thymus GO:0033077 4 0.010
regulation of cell differentiation GO:0045595 393 0.010
positive regulation of immune system process GO:0002684 283 0.010
cardiac muscle cell contraction GO:0086003 4 0.010
spindle elongation GO:0051231 4 0.010
positive regulation of cellular amine metabolic process GO:0033240 7 0.010
neuron development GO:0048666 113 0.010

AARS disease predictions

Disease DO term ID Size Probability Func Analog Org
neuromuscular disease DOID:440 38 0.938
nervous system disease DOID:863 431 0.938
neuropathy DOID:870 52 0.938
central nervous system disease DOID:331 186 0.301
disease of metabolism DOID:0014667 295 0.232
inherited metabolic disorder DOID:655 242 0.232
amino acid metabolic disorder DOID:9252 50 0.098
motor neuron disease DOID:231 27 0.055
distal hereditary motor neuropathy DOID:0050582 5 0.055
motor neuritis DOID:683 5 0.055
neurodegenerative disease DOID:1289 102 0.055
charcot marie tooth disease DOID:10595 33 0.048
sensory system disease DOID:0050155 203 0.020
immune system disease DOID:2914 155 0.019
auditory system disease DOID:2742 53 0.014
charcot marie tooth disease type 2 DOID:0050539 15 0.002