Homo sapiens

22 known processes

ACTN4

actinin, alpha 4

(Aliases: FSGS1,ACTININ-4,FSGS,DKFZp686K23158)

ACTN4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin filament based process GO:0030029 224 0.993
Mouse Fly
actin cytoskeleton organization GO:0030036 207 0.967
Mouse Fly
biological adhesion GO:0022610 331 0.917
Human
cell development GO:0048468 328 0.896
Fly
transmembrane transport GO:0055085 399 0.863
Human
actin filament organization GO:0007015 128 0.840
Mouse
anatomical structure formation involved in morphogenesis GO:0048646 284 0.745
Fly
actomyosin structure organization GO:0031032 59 0.707
Fly
negative regulation of voltage gated calcium channel activity GO:1901386 4 0.683
organelle assembly GO:0070925 176 0.667
Fly
regulation of cell adhesion GO:0030155 166 0.658
cell adhesion GO:0007155 325 0.609
Human
negative regulation of transport GO:0051051 176 0.608
Human
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.597
i kappab kinase nf kappab signaling GO:0007249 166 0.542
system process GO:0003008 349 0.524
positive regulation of transport GO:0051050 336 0.512
Human Mouse
locomotory behavior GO:0007626 1 0.490
Fly
striated muscle cell differentiation GO:0051146 43 0.486
Fly
vesicle mediated transport GO:0016192 371 0.482
Mouse
inorganic ion transmembrane transport GO:0098660 231 0.452
Human
epithelial cell differentiation GO:0030855 141 0.408
cytoplasmic transport GO:0016482 379 0.406
metal ion transport GO:0030001 272 0.394
Human
small gtpase mediated signal transduction GO:0007264 78 0.393
regulation of ion transport GO:0043269 189 0.381
Human
protein targeting to nucleus GO:0044744 104 0.381
response to decreased oxygen levels GO:0036293 96 0.379
Rat
regulation of cell migration GO:0030334 289 0.372
regulation of transmembrane transport GO:0034762 139 0.352
Human
nervous system development GO:0007399 293 0.346
cation transmembrane transport GO:0098655 238 0.334
Human
regulation of protein import into nucleus GO:0042306 78 0.317
regulation of protein localization to nucleus GO:1900180 85 0.314
cell substrate adhesion GO:0031589 132 0.313
Human
adult locomotory behavior GO:0008344 1 0.305
Fly
regulation of ion transmembrane transport GO:0034765 132 0.304
Human
blood vessel endothelial cell migration GO:0043534 42 0.300
actin crosslink formation GO:0051764 1 0.300
negative regulation of ion transport GO:0043271 39 0.297
Human
regulation of cellular component movement GO:0051270 334 0.291
mesendoderm development GO:0048382 1 0.290
g protein coupled receptor signaling pathway GO:0007186 207 0.287
purine nucleoside catabolic process GO:0006152 398 0.283
response to hypoxia GO:0001666 96 0.281
Rat
protein import into nucleus GO:0006606 104 0.281
regulation of protein targeting GO:1903533 91 0.272
nuclear transport GO:0051169 179 0.271
myosin filament assembly GO:0031034 2 0.269
regulation of metal ion transport GO:0010959 120 0.269
Human
cell activation GO:0001775 213 0.268
cellular component assembly involved in morphogenesis GO:0010927 73 0.266
Fly
epithelium development GO:0060429 227 0.261
single organism cellular localization GO:1902580 332 0.261
nucleoside catabolic process GO:0009164 408 0.257
muscle cell differentiation GO:0042692 63 0.247
Fly
cell junction organization GO:0034330 79 0.247
Human Mouse
cell morphogenesis GO:0000902 296 0.247
response to abiotic stimulus GO:0009628 336 0.245
Rat
ameboidal type cell migration GO:0001667 135 0.244
cellular component morphogenesis GO:0032989 314 0.244
Fly
regulation of locomotion GO:0040012 329 0.243
neurological system process GO:0050877 163 0.236
cardiac muscle cell cardiac muscle cell adhesion GO:0086042 1 0.232
embryo development GO:0009790 123 0.229
Worm
regulation of protein localization GO:0032880 296 0.227
Human
regulation of intracellular transport GO:0032386 195 0.226
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.226
purine nucleotide catabolic process GO:0006195 405 0.224
positive regulation of cell proliferation GO:0008284 301 0.223
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.223
protein localization to membrane GO:0072657 160 0.215
regulation of establishment of protein localization GO:0070201 242 0.211
growth GO:0040007 202 0.205
organ morphogenesis GO:0009887 147 0.201
nucleoside triphosphate catabolic process GO:0009143 394 0.200
purine ribonucleoside metabolic process GO:0046128 437 0.199
neurogenesis GO:0022008 169 0.199
blood vessel morphogenesis GO:0048514 162 0.196
cardiovascular system development GO:0072358 262 0.195
ion transmembrane transport GO:0034220 338 0.190
Human
regulation of actin filament based process GO:0032970 141 0.190
mitotic nuclear division GO:0007067 119 0.189
Worm
myofibril assembly GO:0030239 10 0.185
Fly
mitotic cell cycle process GO:1903047 286 0.184
Worm
regulation of cell motility GO:2000145 299 0.184
endomembrane system organization GO:0010256 196 0.184
single organism membrane organization GO:0044802 268 0.184
neuroblast proliferation GO:0007405 4 0.175
memory GO:0007613 3 0.174
actin cytoskeleton reorganization GO:0031532 37 0.174
Fly
cell cell junction organization GO:0045216 69 0.173
Human Mouse
protein import GO:0017038 130 0.171
establishment of protein localization to organelle GO:0072594 172 0.166
protein targeting GO:0006605 187 0.164
post embryonic development GO:0009791 2 0.161
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.160
positive regulation of locomotion GO:0040017 186 0.156
cell matrix adhesion GO:0007160 85 0.154
Human
neuron development GO:0048666 113 0.153
positive regulation of cellular component organization GO:0051130 376 0.153
Mouse
positive regulation of intracellular protein transport GO:0090316 76 0.152
nucleus localization GO:0051647 1 0.151
regulation of actin filament polymerization GO:0030833 50 0.150
cellular amine metabolic process GO:0044106 41 0.148
microtubule cytoskeleton organization GO:0000226 176 0.148
intracellular protein transport GO:0006886 270 0.147
behavior GO:0007610 112 0.144
Fly
regulation of transcription factor import into nucleus GO:0042990 39 0.138
hemostasis GO:0007599 76 0.137
tube development GO:0035295 125 0.136
muscle structure development GO:0061061 98 0.134
Fly
glycosyl compound catabolic process GO:1901658 413 0.134
regulation of growth GO:0040008 165 0.133
response to oxygen levels GO:0070482 100 0.132
Rat
protein localization to organelle GO:0033365 280 0.132
striated muscle myosin thick filament assembly GO:0071688 2 0.132
establishment of protein localization to membrane GO:0090150 121 0.131
positive regulation of cell motility GO:2000147 177 0.131
amine metabolic process GO:0009308 44 0.129
cell projection organization GO:0030030 252 0.129
Human
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 22 0.129
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.127
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.125
positive regulation of cellular amine metabolic process GO:0033240 7 0.123
positive regulation of gtpase activity GO:0043547 166 0.121
positive regulation of intracellular transport GO:0032388 104 0.121
membrane organization GO:0061024 292 0.119
regulation of membrane potential GO:0042391 95 0.117
Human
nucleocytoplasmic transport GO:0006913 176 0.115
ribonucleotide catabolic process GO:0009261 405 0.113
circulatory system development GO:0072359 262 0.111
nuclear import GO:0051170 106 0.111
response to growth factor GO:0070848 205 0.110
nucleoside monophosphate metabolic process GO:0009123 191 0.110
ribonucleoside monophosphate catabolic process GO:0009158 158 0.110
female gamete generation GO:0007292 2 0.109
positive regulation of cellular component movement GO:0051272 181 0.108
purine nucleoside triphosphate catabolic process GO:0009146 392 0.108
endothelial cell migration GO:0043542 86 0.107
atp catabolic process GO:0006200 157 0.107
single organism cell adhesion GO:0098602 179 0.106
guanosine containing compound catabolic process GO:1901069 239 0.106
adherens junction assembly GO:0034333 34 0.106
Human
nucleoside triphosphate metabolic process GO:0009141 422 0.103
actin filament based movement GO:0030048 17 0.102
cell projection morphogenesis GO:0048858 129 0.101
negative regulation of transmembrane transport GO:0034763 29 0.100
Human
rho protein signal transduction GO:0007266 26 0.099
regulation of nucleotide metabolic process GO:0006140 269 0.095
positive regulation of cell migration GO:0030335 172 0.094
angiogenesis GO:0001525 147 0.094
enzyme linked receptor protein signaling pathway GO:0007167 303 0.093
homotypic cell cell adhesion GO:0034109 47 0.092
negative regulation of protein transport GO:0051224 75 0.092
purine ribonucleoside catabolic process GO:0046130 398 0.091
cell migration involved in gastrulation GO:0042074 1 0.091
regulation of vesicle mediated transport GO:0060627 130 0.091
Mouse
cell junction assembly GO:0034329 67 0.090
Human Mouse
purine containing compound catabolic process GO:0072523 411 0.087
cellular response to endogenous stimulus GO:0071495 336 0.087
regulation of cell development GO:0060284 161 0.086
cellular chemical homeostasis GO:0055082 180 0.086
regulation of anatomical structure morphogenesis GO:0022603 286 0.085
regulation of epithelial cell migration GO:0010632 93 0.084
regulation of potassium ion transmembrane transporter activity GO:1901016 16 0.084
Human
nitrogen compound transport GO:0071705 191 0.083
negative regulation of organelle organization GO:0010639 126 0.083
secretion by cell GO:0032940 226 0.083
motor neuron axon guidance GO:0008045 2 0.083
heart contraction GO:0060047 62 0.082
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.081
regulation of cell substrate adhesion GO:0010810 68 0.081
divalent metal ion transport GO:0070838 152 0.081
heart development GO:0007507 95 0.081
regulation of nucleocytoplasmic transport GO:0046822 98 0.081
negative regulation of phosphorus metabolic process GO:0010563 267 0.080
cell chemotaxis GO:0060326 112 0.079
muscle cell development GO:0055001 29 0.079
Fly
regulation of actin cytoskeleton organization GO:0032956 116 0.079
mitotic cell cycle GO:0000278 326 0.078
Worm
sarcomere organization GO:0045214 8 0.078
Fly
regulation of transporter activity GO:0032409 82 0.078
Human
positive regulation of protein localization to nucleus GO:1900182 48 0.078
multicellular organismal aging GO:0010259 3 0.076
guanosine containing compound metabolic process GO:1901068 244 0.075
chemical homeostasis GO:0048878 306 0.075
leukocyte migration GO:0050900 107 0.074
determination of adult lifespan GO:0008340 2 0.074
regulation of cellular ketone metabolic process GO:0010565 50 0.074
negative regulation of cellular component movement GO:0051271 106 0.073
Human Mouse
positive regulation of developmental process GO:0051094 314 0.073
cellular potassium ion transport GO:0071804 60 0.072
Human
single organismal cell cell adhesion GO:0016337 148 0.072
cellular macromolecule catabolic process GO:0044265 380 0.071
purine nucleoside triphosphate metabolic process GO:0009144 412 0.071
single organism nuclear import GO:1902593 104 0.069
vasculature development GO:0001944 181 0.069
anterior posterior axis specification GO:0009948 2 0.069
regulation of cytoplasmic transport GO:1903649 149 0.068
negative regulation of transporter activity GO:0032410 25 0.068
Human
response to wounding GO:0009611 168 0.067
neuronal stem cell division GO:0036445 1 0.067
plasma membrane organization GO:0007009 115 0.066
establishment of nucleus localization GO:0040023 1 0.066
cardiac muscle tissue development GO:0048738 39 0.066
regulation of actin filament length GO:0030832 56 0.065
positive regulation of ion transmembrane transporter activity GO:0032414 29 0.065
Human
positive regulation of transporter activity GO:0032411 32 0.064
Human
blood vessel development GO:0001568 172 0.064
regulation of cell matrix adhesion GO:0001952 42 0.064
negative regulation of apoptotic signaling pathway GO:2001234 97 0.064
regulation of cell differentiation GO:0045595 393 0.064
negative regulation of ion transmembrane transport GO:0034766 26 0.064
Human
regulation of purine nucleotide metabolic process GO:1900542 264 0.063
positive regulation of protein kinase activity GO:0045860 190 0.063
positive regulation of hydrolase activity GO:0051345 331 0.062
cellular amino acid metabolic process GO:0006520 116 0.062
positive regulation of protein phosphorylation GO:0001934 313 0.062
circulatory system process GO:0003013 113 0.062
asymmetric neuroblast division GO:0055059 1 0.061
negative regulation of apoptotic process GO:0043066 316 0.060
purine ribonucleotide catabolic process GO:0009154 404 0.060
regulation of protein transport GO:0051223 213 0.060
mapk cascade GO:0000165 288 0.060
cell cycle arrest GO:0007050 71 0.059
positive regulation of cytoplasmic transport GO:1903651 82 0.058
organophosphate catabolic process GO:0046434 430 0.058
ribonucleoside catabolic process GO:0042454 406 0.058
transcription factor import into nucleus GO:0042991 40 0.057
positive regulation of transferase activity GO:0051347 227 0.057
response to alcohol GO:0097305 64 0.056
cellular protein complex assembly GO:0043623 188 0.056
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.056
cell part morphogenesis GO:0032990 137 0.056
generation of neurons GO:0048699 152 0.056
regulation of small gtpase mediated signal transduction GO:0051056 156 0.055
neuroblast division GO:0055057 1 0.055
maintenance of location GO:0051235 112 0.055
midgut development GO:0007494 1 0.054
divalent inorganic cation transport GO:0072511 158 0.054
positive regulation of protein import into nucleus GO:0042307 46 0.053
chemotaxis GO:0006935 157 0.053
regulation of protein stability GO:0031647 87 0.053
microtubule based process GO:0007017 210 0.052
positive regulation of cell differentiation GO:0045597 211 0.052
secretion GO:0046903 254 0.052
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.051
cellular response to growth factor stimulus GO:0071363 197 0.051
ras protein signal transduction GO:0007265 73 0.050
cellular response to external stimulus GO:0071496 111 0.050
negative regulation of multicellular organismal process GO:0051241 317 0.050
ribonucleoside monophosphate metabolic process GO:0009161 187 0.049
embryonic morphogenesis GO:0048598 85 0.049
negative regulation of potassium ion transmembrane transport GO:1901380 5 0.049
Human
regulation of body fluid levels GO:0050878 99 0.049
positive regulation of response to external stimulus GO:0032103 88 0.049
negative regulation of cell motility GO:2000146 104 0.049
skin development GO:0043588 76 0.048
taxis GO:0042330 157 0.048
purine nucleoside monophosphate catabolic process GO:0009128 158 0.047
sensory perception of mechanical stimulus GO:0050954 37 0.047
myosin filament organization GO:0031033 2 0.047
protein oligomerization GO:0051259 173 0.047
Human
neuron differentiation GO:0030182 138 0.046
protein localization to nucleus GO:0034504 136 0.046
regulation of intracellular protein transport GO:0033157 123 0.046
regulation of neurogenesis GO:0050767 82 0.046
protein autophosphorylation GO:0046777 123 0.046
protein catabolic process GO:0030163 325 0.045
Worm
ribonucleoside triphosphate metabolic process GO:0009199 412 0.045
stem cell division GO:0017145 2 0.044
t cell activation GO:0042110 99 0.044
regulation of protein kinase activity GO:0045859 289 0.044
regulation of cellular amino acid metabolic process GO:0006521 6 0.044
nuclear migration GO:0007097 1 0.043
lens development in camera type eye GO:0002088 2 0.043
adenylate cyclase inhibiting dopamine receptor signaling pathway GO:0007195 4 0.043
neuromuscular junction development GO:0007528 3 0.043
regulation of cytokine production GO:0001817 232 0.043
blastocyst formation GO:0001825 3 0.043
negative regulation of phosphate metabolic process GO:0045936 267 0.042
regulation of transferase activity GO:0051338 355 0.042
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.042
nucleoside monophosphate catabolic process GO:0009125 159 0.042
regulation of cell cycle GO:0051726 393 0.041
posttranscriptional regulation of gene expression GO:0010608 213 0.041
inflammatory response GO:0006954 79 0.040
regulation of protein polymerization GO:0032271 63 0.040
positive regulation of protein transport GO:0051222 135 0.040
establishment of cell polarity GO:0030010 22 0.040
exosomal secretion GO:1990182 15 0.039
sensory perception of sound GO:0007605 37 0.039
platelet aggregation GO:0070527 32 0.039
regulation of nucleoside metabolic process GO:0009118 209 0.039
epithelial cell development GO:0002064 34 0.039
positive regulation of organelle organization GO:0010638 195 0.038
nuclear division GO:0000280 128 0.038
Worm
single organism behavior GO:0044708 28 0.037
Fly
regulation of potassium ion transmembrane transport GO:1901379 20 0.037
Human
purine nucleoside monophosphate metabolic process GO:0009126 186 0.037
organelle fission GO:0048285 149 0.037
Worm
regulation of vasculature development GO:1901342 97 0.037
regulation of exosomal secretion GO:1903541 12 0.037
atp metabolic process GO:0046034 176 0.037
coagulation GO:0050817 78 0.036
salivary gland morphogenesis GO:0007435 4 0.036
protein stabilization GO:0050821 64 0.036
inorganic cation transmembrane transport GO:0098662 194 0.035
Human
regulation of rho protein signal transduction GO:0035023 79 0.035
endocytosis GO:0006897 159 0.035
Mouse
nucleoside phosphate catabolic process GO:1901292 412 0.035
positive regulation of ion transmembrane transport GO:0034767 40 0.035
Human
regulation of cellular amine metabolic process GO:0033238 11 0.035
calcium ion transport GO:0006816 147 0.034
actin polymerization or depolymerization GO:0008154 56 0.034
regulation of apoptotic signaling pathway GO:2001233 175 0.034
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 18 0.034
regulation of actin filament bundle assembly GO:0032231 36 0.034
positive regulation of exocytosis GO:0045921 35 0.034
microtubule organizing center organization GO:0031023 62 0.034
negative regulation of cellular protein metabolic process GO:0032269 353 0.034
negative regulation of cell migration GO:0030336 102 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.034
organelle localization GO:0051640 84 0.033
spermatid differentiation GO:0048515 4 0.033
maintenance of location in cell GO:0051651 62 0.033
regulation of nervous system development GO:0051960 88 0.033
wound healing GO:0042060 115 0.033
negative regulation of locomotion GO:0040013 118 0.032
multicellular organismal signaling GO:0035637 34 0.032
vitamin transport GO:0051180 14 0.032
thiamine transmembrane transport GO:0071934 2 0.032
associative learning GO:0008306 1 0.032
gtp metabolic process GO:0046039 239 0.032
protein localization to plasma membrane GO:0072659 93 0.032
regulation of secretion by cell GO:1903530 177 0.031
fibroblast growth factor receptor signaling pathway GO:0008543 26 0.031
ventricular cardiac muscle cell differentiation GO:0055012 1 0.031
cellular macromolecular complex assembly GO:0034622 324 0.031
regulation of dephosphorylation GO:0035303 96 0.031
regulation of actin filament depolymerization GO:0030834 10 0.031
response to fibroblast growth factor GO:0071774 39 0.030
leukocyte chemotaxis GO:0030595 76 0.030
gtp catabolic process GO:0006184 237 0.030
negative regulation of developmental process GO:0051093 247 0.030
nucleotide catabolic process GO:0009166 408 0.030
regulation of inflammatory response GO:0050727 46 0.029
negative regulation of intracellular signal transduction GO:1902532 183 0.029
tube morphogenesis GO:0035239 95 0.029
regulation of potassium ion transport GO:0043266 24 0.029
Human
ectoderm development GO:0007398 3 0.029
leukocyte activation GO:0045321 164 0.029
establishment of organelle localization GO:0051656 59 0.029
regulation of peptide transport GO:0090087 62 0.029
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.029
vitamin transmembrane transport GO:0035461 4 0.028
mitochondrion organization GO:0007005 156 0.028
muscle contraction GO:0006936 73 0.028
regulation of protein complex assembly GO:0043254 147 0.028
positive regulation of map kinase activity GO:0043406 80 0.028
protein homooligomerization GO:0051260 100 0.028
Human
cell substrate adherens junction assembly GO:0007045 30 0.027
Human
cell projection assembly GO:0030031 126 0.027
Human
signal transduction by phosphorylation GO:0023014 297 0.027
regulation of angiogenesis GO:0045765 92 0.027
regulation of nucleotide catabolic process GO:0030811 205 0.027
chromatin modification GO:0016568 298 0.027
spermatid development GO:0007286 4 0.027
elastic fiber assembly GO:0048251 3 0.027
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.027
regulation of rho gtpase activity GO:0032319 66 0.026
platelet morphogenesis GO:0036344 4 0.026
cilium morphogenesis GO:0060271 75 0.026
positive regulation of growth GO:0045927 58 0.026
sensory perception GO:0007600 103 0.026
response to oxygen containing compound GO:1901700 369 0.026
morphogenesis of embryonic epithelium GO:0016331 4 0.026
central nervous system development GO:0007417 123 0.026
modification dependent protein catabolic process GO:0019941 209 0.026
regulation of response to external stimulus GO:0032101 222 0.026
positive regulation of ion transport GO:0043270 87 0.026
Human
prostate gland morphogenesis GO:0060512 1 0.025
adult behavior GO:0030534 18 0.025
Fly
mrna metabolic process GO:0016071 175 0.025
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.025
cellular response to oxygen containing compound GO:1901701 276 0.025
negative regulation of protein modification process GO:0031400 200 0.025
cellular ketone metabolic process GO:0042180 80 0.025
negative regulation of intracellular protein transport GO:0090317 42 0.025
cell substrate junction assembly GO:0007044 35 0.024
Human
response to lipid GO:0033993 206 0.024
golgi vesicle transport GO:0048193 80 0.024
adherens junction organization GO:0034332 36 0.024
Human
meiosis i GO:0007127 4 0.024
vocalization behavior GO:0071625 11 0.024
cell fate determination GO:0001709 3 0.024
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.024
blood circulation GO:0008015 113 0.024
positive regulation of rho gtpase activity GO:0032321 56 0.024
establishment or maintenance of cell polarity GO:0007163 31 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.023
blastocyst development GO:0001824 3 0.023
potassium ion transmembrane transport GO:0071805 60 0.023
Human
cation transport GO:0006812 331 0.023
Human
positive regulation of exosomal secretion GO:1903543 12 0.023
regulation of calcium ion transport GO:0051924 79 0.023
neuron projection morphogenesis GO:0048812 50 0.023
histone modification GO:0016570 251 0.023
cellular response to hypoxia GO:0071456 51 0.023
vasodilation GO:0042311 4 0.022
cellular response to dna damage stimulus GO:0006974 379 0.022
positive regulation of nucleotide metabolic process GO:0045981 230 0.022
regulation of oxidoreductase activity GO:0051341 43 0.022
cell cell signaling GO:0007267 155 0.022
response to nitrogen compound GO:1901698 184 0.022
neuron projection development GO:0031175 106 0.022
negative regulation of cell death GO:0060548 345 0.022
spindle organization GO:0007051 53 0.022
somatic stem cell division GO:0048103 1 0.022
regulation of cellular response to stress GO:0080135 244 0.022
regulation of gtpase activity GO:0043087 180 0.022
carbohydrate derivative biosynthetic process GO:1901137 207 0.022
regulation of secretion GO:0051046 194 0.022
tissue morphogenesis GO:0048729 96 0.022
mitotic cell cycle phase transition GO:0044772 162 0.022
protein polymerization GO:0051258 71 0.022
regulation of protein localization to cell surface GO:2000008 15 0.022
Human
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.021
negative regulation of intracellular transport GO:0032387 60 0.021
regulation of mitotic cell cycle GO:0007346 189 0.021
action potential GO:0001508 34 0.021
response to other organism GO:0051707 261 0.021
lipid biosynthetic process GO:0008610 177 0.021
neural tube formation GO:0001841 3 0.021
dopamine receptor signaling pathway GO:0007212 10 0.021
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.021
negative regulation of cell cycle GO:0045786 193 0.020
hemopoiesis GO:0030097 180 0.020
regulation of ion homeostasis GO:2000021 73 0.020
viral process GO:0016032 146 0.020
negative regulation of catagen GO:0051796 1 0.020
actin filament polymerization GO:0030041 45 0.020
organophosphate biosynthetic process GO:0090407 163 0.020
tissue migration GO:0090130 119 0.020
embryo development ending in birth or egg hatching GO:0009792 34 0.020
Worm
morphogenesis of an epithelium GO:0002009 60 0.020
myeloid leukocyte migration GO:0097529 62 0.020
regulation of gtp catabolic process GO:0033124 180 0.020
actin mediated cell contraction GO:0070252 12 0.019
thiamine transport GO:0015888 3 0.019
regulation of meiotic cell cycle GO:0051445 4 0.019
response to inorganic substance GO:0010035 127 0.019
maintenance of protein location GO:0045185 57 0.019
syncytium formation by plasma membrane fusion GO:0000768 2 0.019
hematopoietic or lymphoid organ development GO:0048534 186 0.019
early endosome to late endosome transport GO:0045022 21 0.019
cellular divalent inorganic cation homeostasis GO:0072503 128 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.019
rna catabolic process GO:0006401 71 0.019
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.019
long term memory GO:0007616 2 0.018
molting cycle GO:0042303 28 0.018
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 29 0.018
regulation of endopeptidase activity GO:0052548 170 0.018
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.018
myeloid cell differentiation GO:0030099 117 0.018
muscle tissue development GO:0060537 62 0.018

ACTN4 disease predictions

Disease DO term ID Size Probability Func Analog Org
cardiovascular system disease DOID:1287 106 0.314
auditory system disease DOID:2742 53 0.096
sensory system disease DOID:0050155 203 0.096
nervous system disease DOID:863 431 0.096
musculoskeletal system disease DOID:17 223 0.068
autosomal dominant nonsyndromic deafness DOID:0050564 23 0.059
nonsyndromic deafness DOID:0050563 50 0.059
immune system disease DOID:2914 155 0.057
bone disease DOID:0080001 88 0.055
connective tissue disease DOID:65 109 0.055
muscular disease DOID:0080000 114 0.046
heart disease DOID:114 68 0.043
central nervous system disease DOID:331 186 0.039
epilepsy syndrome DOID:1826 41 0.035
brain disease DOID:936 73 0.035
muscle tissue disease DOID:66 113 0.032
kidney disease DOID:557 36 0.031
urinary system disease DOID:18 40 0.031
neuropathy DOID:870 52 0.031
myopathy DOID:423 104 0.027
muscular dystrophy DOID:9884 51 0.027
cardiomyopathy DOID:0050700 50 0.024
integumentary system disease DOID:16 43 0.022
bone development disease DOID:0080006 55 0.021
limb girdle muscular dystrophy DOID:11724 25 0.020