|
|
atrial septum primum morphogenesis
|
GO:0003289 |
1 |
0.949
|
|
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
0.922
|
|
|
|
mitral valve morphogenesis
|
GO:0003183 |
2 |
0.913
|
|
|
|
cardiac muscle cell fate commitment
|
GO:0060923 |
4 |
0.822
|
|
|
|
positive regulation of pathway restricted smad protein phosphorylation
|
GO:0010862 |
22 |
0.810
|
|
|
|
negative regulation of chondrocyte proliferation
|
GO:1902731 |
1 |
0.802
|
Human |
|
|
negative regulation of trophoblast cell migration
|
GO:1901164 |
3 |
0.749
|
Human |
|
|
endocardial cushion cell differentiation
|
GO:0061443 |
1 |
0.696
|
|
|
|
muscle cell fate commitment
|
GO:0042693 |
4 |
0.668
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.662
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.656
|
|
|
|
endocardial cushion development
|
GO:0003197 |
3 |
0.654
|
|
|
|
endocardial cell differentiation
|
GO:0060956 |
2 |
0.638
|
|
|
|
positive regulation of determination of dorsal identity
|
GO:2000017 |
1 |
0.632
|
|
|
|
positive regulation of erythrocyte differentiation
|
GO:0045648 |
11 |
0.608
|
Human |
|
|
atrial septum morphogenesis
|
GO:0060413 |
5 |
0.599
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.578
|
|
|
|
bone mineralization
|
GO:0030282 |
34 |
0.528
|
|
|
|
positive regulation of trophoblast cell migration
|
GO:1901165 |
2 |
0.525
|
Human |
|
|
epithelial cell fate commitment
|
GO:0072148 |
3 |
0.523
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.522
|
|
|
|
regulation of determination of dorsal identity
|
GO:2000015 |
2 |
0.508
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.504
|
Human |
|
|
skeletal system development
|
GO:0001501 |
79 |
0.481
|
Human |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.462
|
Human |
|
|
activin receptor signaling pathway
|
GO:0032924 |
24 |
0.433
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.413
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.413
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.411
|
|
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.407
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.385
|
Human |
|
|
regulation of lung blood pressure
|
GO:0014916 |
1 |
0.384
|
Human |
|
|
regulation of axon guidance
|
GO:1902667 |
3 |
0.382
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.381
|
Human Worm |
|
|
tube development
|
GO:0035295 |
125 |
0.376
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.371
|
Human |
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
38 |
0.369
|
Human |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.369
|
Human |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.367
|
Human |
|
|
digestive system development
|
GO:0055123 |
75 |
0.365
|
Mouse |
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.364
|
Human |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.354
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.354
|
Human Worm |
|
|
chondrocyte proliferation
|
GO:0035988 |
4 |
0.349
|
Human |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.344
|
Human |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.344
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.344
|
Human |
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
26 |
0.339
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.328
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.325
|
Human Mouse Fly |
|
|
epithelium development
|
GO:0060429 |
227 |
0.322
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.321
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.311
|
Human |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.311
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.311
|
Human |
|
|
cardiac endothelial cell differentiation
|
GO:0003348 |
2 |
0.305
|
|
|
|
regulation of axon extension involved in axon guidance
|
GO:0048841 |
2 |
0.305
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.301
|
|
|
|
retina vasculature development in camera type eye
|
GO:0061298 |
3 |
0.299
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.296
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.293
|
Human Mouse |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.291
|
|
|
|
negative regulation of systemic arterial blood pressure
|
GO:0003085 |
1 |
0.285
|
Human |
|
|
endocardial cell fate commitment
|
GO:0060957 |
1 |
0.283
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.282
|
Human Fly |
|
|
endocardial cushion cell fate commitment
|
GO:0061445 |
1 |
0.281
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.279
|
Human |
|
|
atrioventricular valve development
|
GO:0003171 |
3 |
0.278
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.275
|
Human |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.270
|
Human |
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.268
|
Human |
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.267
|
Human |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.255
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.249
|
|
|
|
atrioventricular valve morphogenesis
|
GO:0003181 |
2 |
0.246
|
|
|
|
regulation of smad protein import into nucleus
|
GO:0060390 |
10 |
0.246
|
Human |
|
|
determination of dorsal identity
|
GO:0048263 |
4 |
0.245
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.244
|
Human Worm |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.244
|
Human |
|
|
digestive tract development
|
GO:0048565 |
75 |
0.240
|
Mouse |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.236
|
Human |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.236
|
Human |
|
|
positive regulation of biomineral tissue development
|
GO:0070169 |
20 |
0.235
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.233
|
|
|
|
septum primum development
|
GO:0003284 |
1 |
0.233
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.232
|
Human Worm Fly |
|
|
positive regulation of homeostatic process
|
GO:0032846 |
47 |
0.230
|
Human |
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.229
|
Human Worm |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.227
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.226
|
Human |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.222
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.220
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.219
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.217
|
Fly |
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.215
|
Human |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.214
|
Human |
|
|
chorionic trophoblast cell proliferation
|
GO:0097360 |
2 |
0.209
|
Human |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.206
|
Human |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.205
|
Human |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.204
|
Human |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.203
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.202
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.202
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.201
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.196
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.195
|
Human Mouse Fly |
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.195
|
Human |
|
|
cardiac atrium morphogenesis
|
GO:0003209 |
7 |
0.195
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.194
|
Human |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.194
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.192
|
Human |
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.190
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.190
|
Human |
|
|
cardiac atrium development
|
GO:0003230 |
10 |
0.188
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.187
|
Human |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.186
|
Human |
|
|
ossification
|
GO:0001503 |
121 |
0.186
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.184
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.183
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.181
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.181
|
Human |
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.176
|
Human |
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.176
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.175
|
Human |
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.175
|
Mouse |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.174
|
Human Fly |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.174
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.174
|
Human |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.173
|
Human |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.170
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.170
|
Human |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.170
|
Human Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.170
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.169
|
Human |
|
|
response to lipid
|
GO:0033993 |
206 |
0.168
|
Human Rat |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.167
|
Human |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.166
|
Human |
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
38 |
0.165
|
|
|
|
cardiac septum morphogenesis
|
GO:0060411 |
9 |
0.163
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.163
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.161
|
Human |
|
|
response to sterol
|
GO:0036314 |
14 |
0.161
|
Human |
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.160
|
Human |
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.160
|
Human Mouse |
|
|
regulation of adherens junction organization
|
GO:1903391 |
21 |
0.158
|
Human |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.155
|
Human |
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
37 |
0.155
|
Human |
|
|
segmentation
|
GO:0035282 |
4 |
0.150
|
Fly |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.150
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.148
|
Human Mouse |
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.148
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.147
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.146
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.144
|
Human |
|
|
immune system development
|
GO:0002520 |
195 |
0.142
|
Human |
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.141
|
Human |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.140
|
Worm |
|
|
cardiac chamber development
|
GO:0003205 |
30 |
0.137
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.137
|
Human |
|
|
nervous system development
|
GO:0007399 |
293 |
0.137
|
Fly |
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.132
|
Human |
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.132
|
Human |
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.132
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.131
|
Fly |
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.130
|
Human |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.130
|
Fly |
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.130
|
Human |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.128
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.128
|
Human Mouse |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.127
|
Human |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.127
|
Human |
|
|
gastrulation
|
GO:0007369 |
51 |
0.127
|
Mouse |
|
|
cell junction organization
|
GO:0034330 |
79 |
0.126
|
Human |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.126
|
Human |
|
|
dorsal ventral pattern formation
|
GO:0009953 |
15 |
0.125
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.125
|
Human Fly |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.125
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.124
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.124
|
Human |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.124
|
Human |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.123
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.121
|
Mouse |
|
|
cation transport
|
GO:0006812 |
331 |
0.120
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.119
|
Human |
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.119
|
Human |
|
|
atrial septum development
|
GO:0003283 |
8 |
0.118
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.117
|
Human |
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.116
|
Human |
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.116
|
Human |
|
|
regulation of focal adhesion assembly
|
GO:0051893 |
20 |
0.116
|
Human |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.115
|
Human Worm |
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.115
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.114
|
|
|
|
growth
|
GO:0040007 |
202 |
0.114
|
Human Worm Fly |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.114
|
Human Rat |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.114
|
Rat |
|
|
regulation of system process
|
GO:0044057 |
101 |
0.113
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.112
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.111
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.111
|
Human |
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.109
|
Human |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.109
|
Human |
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.109
|
Human |
|
|
blood vessel remodeling
|
GO:0001974 |
2 |
0.108
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.108
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.108
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.108
|
|
|
|
endocardium development
|
GO:0003157 |
2 |
0.106
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.106
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.106
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.105
|
|
|
|
negative regulation of blood pressure
|
GO:0045776 |
3 |
0.104
|
Human |
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.104
|
|
|
|
lung development
|
GO:0030324 |
20 |
0.104
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.103
|
Human |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.102
|
Human |
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.102
|
Human |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.102
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.102
|
Rat |
|
|
mesoderm morphogenesis
|
GO:0048332 |
11 |
0.101
|
Mouse |
|
|
wound healing
|
GO:0042060 |
115 |
0.101
|
Human |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.101
|
Fly |
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.101
|
Human |
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
8 |
0.100
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.100
|
Human |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.100
|
Human Rat |
|
|
protein import
|
GO:0017038 |
130 |
0.099
|
Human |
|
|
negative regulation of chorionic trophoblast cell proliferation
|
GO:1901383 |
2 |
0.098
|
Human |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.097
|
Worm Fly |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.096
|
Human |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.095
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.094
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.094
|
Human |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.093
|
Human Worm |
|
|
cartilage development
|
GO:0051216 |
31 |
0.092
|
Human |
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
17 |
0.091
|
Human |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.090
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.089
|
Human |
|
|
regulation of activin receptor signaling pathway
|
GO:0032925 |
14 |
0.089
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.088
|
Human |
|
|
defense response
|
GO:0006952 |
315 |
0.088
|
Mouse Worm Fly |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.088
|
Worm |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.088
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.088
|
Human |
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
29 |
0.088
|
Human |
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.087
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.086
|
Worm |
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.085
|
Human |
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.085
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.085
|
Human Worm |
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.085
|
Human |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.085
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.085
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.084
|
Human |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.084
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.084
|
Human Worm Fly |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.082
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.082
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.080
|
Worm Fly |
|
|
organ formation
|
GO:0048645 |
3 |
0.080
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.080
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.080
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.080
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.079
|
|
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
19 |
0.079
|
Human |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.079
|
|
|
|
dna biosynthetic process
|
GO:0071897 |
40 |
0.079
|
Human |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.078
|
|
|
|
system process
|
GO:0003008 |
349 |
0.078
|
Human |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.078
|
Human |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.077
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.077
|
Human |
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.076
|
Human |
|
|
angiogenesis
|
GO:0001525 |
147 |
0.076
|
Human Mouse |
|
|
chondrocyte development
|
GO:0002063 |
1 |
0.076
|
Human |
|
|
response to wounding
|
GO:0009611 |
168 |
0.075
|
Human |
|
|
oogenesis
|
GO:0048477 |
2 |
0.075
|
Fly |
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.075
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.075
|
Human |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.075
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.075
|
Human |
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.074
|
Human |
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
30 |
0.074
|
Human |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.073
|
|
|
|
regulation of bone mineralization
|
GO:0030500 |
29 |
0.073
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.073
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.072
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.072
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.072
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.071
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.070
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.070
|
|
|
|
regulation of chorionic trophoblast cell proliferation
|
GO:1901382 |
2 |
0.070
|
Human |
|
|
appendage development
|
GO:0048736 |
23 |
0.069
|
Human Fly |
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.069
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.069
|
Human |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.069
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.068
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.067
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.067
|
Human |
|
|
metal ion transport
|
GO:0030001 |
272 |
0.067
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.067
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.066
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.066
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.066
|
Human |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.066
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.066
|
Human |
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.066
|
Human |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.066
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.066
|
Fly |
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.066
|
Human |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.065
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.065
|
|
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.065
|
Human |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.064
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.064
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.064
|
Human |
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.064
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.063
|
Human |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.063
|
Human |
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.063
|
Human |
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.062
|
Fly |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.062
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.062
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.061
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.061
|
Mouse |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.061
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.060
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.060
|
Human |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.060
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.060
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.060
|
Human |
|
|
central nervous system development
|
GO:0007417 |
123 |
0.059
|
|
|
|
sodium ion transport
|
GO:0006814 |
61 |
0.059
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
16 |
0.059
|
Human Fly |
|
|
muscle system process
|
GO:0003012 |
81 |
0.058
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.058
|
Human |
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.058
|
Fly |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.057
|
Human |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.057
|
|
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
12 |
0.057
|
Human |
|
|
reproductive process
|
GO:0022414 |
106 |
0.057
|
Human Mouse Worm Fly |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.056
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.056
|
Human Mouse Fly |
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.055
|
Fly |
|
|
pattern specification process
|
GO:0007389 |
43 |
0.055
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.055
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.055
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.055
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.054
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.054
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.054
|
Worm |
|
|
camera type eye development
|
GO:0043010 |
25 |
0.054
|
|
|
|
response to cholesterol
|
GO:0070723 |
11 |
0.054
|
Human |
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.054
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.054
|
|
|
|
mating
|
GO:0007618 |
1 |
0.053
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.052
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.052
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.052
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.052
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.052
|
Human |
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.051
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.051
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.051
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.051
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.050
|
Worm Fly |
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.050
|
Human |
|
|
positive regulation of smad protein import into nucleus
|
GO:0060391 |
8 |
0.050
|
Human |
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.050
|
Human |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.050
|
Worm |
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.050
|
Human |
|
|
respiratory system development
|
GO:0060541 |
22 |
0.049
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
15 |
0.049
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.049
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.049
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.049
|
Human |
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.048
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.048
|
Human |
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.048
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.048
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.048
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.048
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.047
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.047
|
Human |
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.047
|
Human |
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.047
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.047
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.046
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.046
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.046
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.046
|
|
|
|
cellular response to bmp stimulus
|
GO:0071773 |
8 |
0.045
|
Human |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.045
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.044
|
Fly |
|
|
mitral valve development
|
GO:0003174 |
3 |
0.044
|
|
|
|
negative regulation of cell matrix adhesion
|
GO:0001953 |
14 |
0.044
|
Human |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.044
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.044
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
18 |
0.044
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.043
|
Fly |
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.043
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.043
|
Human |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.043
|
Human |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.043
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.043
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.043
|
Human |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.043
|
Human |
|
|
memory
|
GO:0007613 |
3 |
0.043
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.043
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.043
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.042
|
|
|
|
smad protein import into nucleus
|
GO:0007184 |
13 |
0.042
|
Human |
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.042
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.042
|
Worm Fly |
|
|
response to starvation
|
GO:0042594 |
59 |
0.042
|
Human |
|
|
chondrocyte differentiation
|
GO:0002062 |
17 |
0.042
|
Human |
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.041
|
Human |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.041
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.041
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.041
|
Human |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.041
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.041
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.040
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.040
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.040
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.040
|
|
|
|
negative regulation of blood circulation
|
GO:1903523 |
4 |
0.040
|
|
|
|
heart valve morphogenesis
|
GO:0003179 |
8 |
0.040
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.040
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.039
|
Human |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.039
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.039
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.039
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.038
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.038
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.038
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.038
|
|
|
|
vascular endothelial growth factor receptor signaling pathway
|
GO:0048010 |
19 |
0.038
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.038
|
Human |
|
|
negative regulation of cell substrate adhesion
|
GO:0010812 |
24 |
0.038
|
Human |
|
|
apoptotic nuclear changes
|
GO:0030262 |
13 |
0.038
|
Human |
|
|
execution phase of apoptosis
|
GO:0097194 |
32 |
0.037
|
Human |
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.037
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.037
|
|
|
|
regulation of growth rate
|
GO:0040009 |
1 |
0.036
|
|
|
|
wound healing spreading of epidermal cells
|
GO:0035313 |
6 |
0.036
|
Human |
|
|
regulation of blood pressure
|
GO:0008217 |
30 |
0.036
|
Human |
|
|
response to bmp
|
GO:0071772 |
8 |
0.036
|
Human |
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.036
|
Fly |
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.036
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.036
|
|
|
|
cardiac cell fate commitment
|
GO:0060911 |
7 |
0.036
|
|
|
|
negative regulation of blood vessel endothelial cell migration
|
GO:0043537 |
16 |
0.036
|
Human |
|
|
skin development
|
GO:0043588 |
76 |
0.035
|
|
|
|
respiratory tube development
|
GO:0030323 |
20 |
0.035
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.035
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.035
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.035
|
Human Mouse |
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.035
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.035
|
Fly |
|
|
lymphatic endothelial cell differentiation
|
GO:0060836 |
3 |
0.034
|
Human |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.034
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.034
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.034
|
Human |
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.034
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.034
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.034
|
|
|
|
negative regulation of activin receptor signaling pathway
|
GO:0032926 |
6 |
0.034
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.033
|
Human |
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.033
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.033
|
Human |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.033
|
|
|
|
negative regulation of type 2 immune response
|
GO:0002829 |
3 |
0.033
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.033
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.033
|
Fly |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.032
|
|
|
|
regulation of cell junction assembly
|
GO:1901888 |
29 |
0.032
|
Human |
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.032
|
Human |
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.032
|
Human |
|
|
specification of symmetry
|
GO:0009799 |
16 |
0.032
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.031
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.031
|
|
|
|
nodal signaling pathway
|
GO:0038092 |
5 |
0.031
|
Human |
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.031
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.031
|
|
