Homo sapiens

0 known processes

ADAM12

ADAM metallopeptidase domain 12

(Aliases: MLTNA,MLTN,MCMPMltna,MCMP)

ADAM12 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.538
negative regulation of embryonic development GO:0045992 4 0.538
regulation of cellular component movement GO:0051270 334 0.519
Human
embryonic skeletal joint morphogenesis GO:0060272 2 0.495
soft palate development GO:0060023 3 0.452
negative regulation of gastrulation GO:2000542 4 0.436
skeletal system development GO:0001501 79 0.431
tissue morphogenesis GO:0048729 96 0.402
Human
ossification GO:0001503 121 0.383
negative regulation of developmental process GO:0051093 247 0.377
enzyme linked receptor protein signaling pathway GO:0007167 303 0.374
Human
embryonic morphogenesis GO:0048598 85 0.366
gastrulation GO:0007369 51 0.323
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.313
Human
endodermal cell differentiation GO:0035987 31 0.313
regulation of cell differentiation GO:0045595 393 0.312
cellular response to endogenous stimulus GO:0071495 336 0.307
Human
negative regulation of endodermal cell differentiation GO:1903225 2 0.293
epithelium development GO:0060429 227 0.289
Human
cellular response to growth factor stimulus GO:0071363 197 0.280
Human
negative regulation of multicellular organismal process GO:0051241 317 0.270
Human
positive regulation of cell differentiation GO:0045597 211 0.266
anatomical structure formation involved in morphogenesis GO:0048646 284 0.263
Human
organ morphogenesis GO:0009887 147 0.250
regulation of locomotion GO:0040012 329 0.240
Human
cell substrate adhesion GO:0031589 132 0.238
Human
response to cytokine GO:0034097 232 0.233
Human
negative regulation of bmp signaling pathway GO:0030514 17 0.207
mesenchyme development GO:0060485 59 0.205
regulation of cell morphogenesis GO:0022604 153 0.205
ras protein signal transduction GO:0007265 73 0.204
positive regulation of locomotion GO:0040017 186 0.192
Human
negative regulation of cell differentiation GO:0045596 171 0.190
bmp signaling pathway GO:0030509 49 0.185
protein catabolic process GO:0030163 325 0.184
regulation of endodermal cell differentiation GO:1903224 3 0.183
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.183
Human
regulation of cell adhesion GO:0030155 166 0.183
Human
blood vessel development GO:0001568 172 0.182
positive regulation of phosphorylation GO:0042327 394 0.182
Human
mesenchymal cell development GO:0014031 50 0.173
regulation of cell migration GO:0030334 289 0.172
Human
osteoblast differentiation GO:0001649 92 0.168
cell morphogenesis GO:0000902 296 0.163
tube morphogenesis GO:0035239 95 0.158
morphogenesis of an epithelium GO:0002009 60 0.157
Human
positive regulation of immune system process GO:0002684 283 0.153
Human
embryonic skeletal joint development GO:0072498 2 0.151
regulation of anatomical structure morphogenesis GO:0022603 286 0.141
Human
inner ear morphogenesis GO:0042472 4 0.140
regulation of bmp signaling pathway GO:0030510 27 0.136
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.136
Human
formation of primary germ layer GO:0001704 42 0.131
collagen metabolic process GO:0032963 28 0.130
positive regulation of developmental process GO:0051094 314 0.128
Human
negative regulation of cell proliferation GO:0008285 228 0.126
detection of mechanical stimulus GO:0050982 4 0.126
immune response GO:0006955 307 0.118
Human
cardiovascular system development GO:0072358 262 0.118
small gtpase mediated signal transduction GO:0007264 78 0.118
membrane protein proteolysis GO:0033619 38 0.115
Human
blood vessel morphogenesis GO:0048514 162 0.111
positive regulation of cell death GO:0010942 263 0.109
detection of mechanical stimulus involved in sensory perception GO:0050974 1 0.109
cellular component morphogenesis GO:0032989 314 0.106
regulation of cellular amino acid metabolic process GO:0006521 6 0.105
cellular amino acid metabolic process GO:0006520 116 0.105
rho protein signal transduction GO:0007266 26 0.105
positive regulation of cellular amine metabolic process GO:0033240 7 0.105
positive regulation of cellular component organization GO:0051130 376 0.104
Human
tube development GO:0035295 125 0.103
skeletal system morphogenesis GO:0048705 24 0.102
regulation of leukocyte activation GO:0002694 115 0.098
extracellular matrix organization GO:0030198 41 0.097
cellular response to oxygen containing compound GO:1901701 276 0.097
Human
regulation of cell motility GO:2000145 299 0.096
Human
skin development GO:0043588 76 0.091
Human
positive regulation of programmed cell death GO:0043068 249 0.091
negative regulation of phosphorylation GO:0042326 174 0.089
positive regulation of catabolic process GO:0009896 310 0.088
sensory organ morphogenesis GO:0090596 21 0.086
response to organophosphorus GO:0046683 41 0.086
regulation of cell growth GO:0001558 135 0.086
Human
positive regulation of cell migration GO:0030335 172 0.084
Human
regulation of protein catabolic process GO:0042176 155 0.082
hair follicle morphogenesis GO:0031069 2 0.082
cellular response to camp GO:0071320 21 0.081
biomineral tissue development GO:0031214 39 0.081
multicellular organismal macromolecule metabolic process GO:0044259 29 0.081
positive regulation of cellular catabolic process GO:0031331 284 0.081
positive regulation of cellular component movement GO:0051272 181 0.080
Human
carbohydrate metabolic process GO:0005975 207 0.080
regulation of epithelial to mesenchymal transition GO:0010717 37 0.079
negative regulation of smooth muscle cell migration GO:0014912 7 0.078
single organism carbohydrate metabolic process GO:0044723 193 0.078
cell development GO:0048468 328 0.076
negative regulation of protein metabolic process GO:0051248 391 0.076
detection of stimulus GO:0051606 85 0.075
biological adhesion GO:0022610 331 0.075
Human
urogenital system development GO:0001655 65 0.075
circulatory system development GO:0072359 262 0.074
positive regulation of proteolysis GO:0045862 142 0.074
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.074
positive regulation of cell proliferation GO:0008284 301 0.074
Human
nerve development GO:0021675 4 0.073
positive regulation of apoptotic process GO:0043065 246 0.073
regulation of muscle tissue development GO:1901861 26 0.073
response to camp GO:0051591 25 0.073
regulation of canonical wnt signaling pathway GO:0060828 88 0.073
negative regulation of cellular component movement GO:0051271 106 0.072
Human
negative regulation of cellular protein metabolic process GO:0032269 353 0.071
membrane organization GO:0061024 292 0.071
cellular response to cytokine stimulus GO:0071345 181 0.070
negative regulation of phosphate metabolic process GO:0045936 267 0.070
mesenchymal cell differentiation GO:0048762 52 0.069
embryonic organ morphogenesis GO:0048562 24 0.069
monosaccharide metabolic process GO:0005996 74 0.068
regulation of smooth muscle cell proliferation GO:0048660 28 0.068
otic vesicle development GO:0071599 1 0.067
regulation of muscle organ development GO:0048634 27 0.066
cell morphogenesis involved in differentiation GO:0000904 144 0.066
cytokine production GO:0001816 247 0.065
Human
response to organonitrogen compound GO:0010243 156 0.065
cellular response to nitrogen compound GO:1901699 144 0.065
negative regulation of cell migration GO:0030336 102 0.065
Human
negative regulation of insulin like growth factor receptor signaling pathway GO:0043569 4 0.064
regulation of smooth muscle cell migration GO:0014910 15 0.064
regulation of striated muscle cell differentiation GO:0051153 25 0.063
endoderm formation GO:0001706 33 0.063
regulation of cell activation GO:0050865 125 0.062
response to oxygen containing compound GO:1901700 369 0.062
Human
bone trabecula morphogenesis GO:0061430 1 0.061
response to wounding GO:0009611 168 0.061
Human
negative regulation of phosphorus metabolic process GO:0010563 267 0.061
response to organic cyclic compound GO:0014070 204 0.060
post embryonic development GO:0009791 2 0.060
positive regulation of protein catabolic process GO:0045732 75 0.060
transmembrane transport GO:0055085 399 0.060
regulation of proteolysis GO:0030162 293 0.060
positive regulation of lymphocyte activation GO:0051251 73 0.060
wnt signaling pathway GO:0016055 156 0.058
positive regulation of cell motility GO:2000147 177 0.058
Human
response to transforming growth factor beta GO:0071559 94 0.058
Human
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.058
epidermis morphogenesis GO:0048730 3 0.058
regulation of wnt signaling pathway GO:0030111 123 0.058
ameboidal type cell migration GO:0001667 135 0.058
Human
positive regulation of epithelial cell proliferation involved in wound healing GO:0060054 3 0.057
response to growth factor GO:0070848 205 0.056
Human
cell growth GO:0016049 160 0.056
Human
embryo development GO:0009790 123 0.056
regulation of cellular component biogenesis GO:0044087 281 0.056
odontogenesis GO:0042476 25 0.056
negative regulation of immune system process GO:0002683 136 0.056
cartilage development GO:0051216 31 0.055
regulation of growth GO:0040008 165 0.055
Human
regulation of stem cell differentiation GO:2000736 56 0.055
negative regulation of protein modification process GO:0031400 200 0.055
positive regulation of cytokine production GO:0001819 167 0.055
Human
digestive tract development GO:0048565 75 0.055
sensory organ development GO:0007423 52 0.054
positive regulation of leukocyte activation GO:0002696 80 0.054
regulation of keratinocyte migration GO:0051547 4 0.054
Human
regulation of lymphocyte activation GO:0051249 103 0.054
regulation of muscle cell differentiation GO:0051147 31 0.053
regeneration GO:0031099 4 0.053
regulation of mapk cascade GO:0043408 262 0.053
Human
translation GO:0006412 132 0.053
response to biotic stimulus GO:0009607 276 0.052
Human
cellular response to organic cyclic compound GO:0071407 127 0.052
bone trabecula formation GO:0060346 1 0.052
embryonic skeletal system development GO:0048706 13 0.051
muscle cell migration GO:0014812 19 0.051
membrane protein ectodomain proteolysis GO:0006509 33 0.051
Human
response to abiotic stimulus GO:0009628 336 0.051
Human
chordate embryonic development GO:0043009 34 0.050
cell adhesion GO:0007155 325 0.050
Human
positive regulation of epithelial to mesenchymal transition GO:0010718 22 0.050
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.050
Human
response to nitrogen compound GO:1901698 184 0.050
regulation of cell development GO:0060284 161 0.049
positive regulation of keratinocyte migration GO:0051549 4 0.049
Human
cranial nerve development GO:0021545 4 0.049
cellular response to organonitrogen compound GO:0071417 124 0.048
visual perception GO:0007601 27 0.047
digestive system development GO:0055123 75 0.047
hair cycle GO:0042633 28 0.047
positive regulation of lymphocyte proliferation GO:0050671 46 0.047
endomembrane system organization GO:0010256 196 0.047
positive regulation of mapk cascade GO:0043410 190 0.046
Human
multicellular organismal metabolic process GO:0044236 34 0.046
positive regulation of leukocyte proliferation GO:0070665 48 0.046
sensory perception GO:0007600 103 0.046
leukocyte activation GO:0045321 164 0.045
Human
protein localization to nucleus GO:0034504 136 0.045
protein localization to organelle GO:0033365 280 0.044
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.044
negative regulation of locomotion GO:0040013 118 0.043
Human
positive regulation of t cell proliferation GO:0042102 33 0.043
detection of stimulus involved in sensory perception GO:0050906 43 0.043
extracellular structure organization GO:0043062 41 0.043
digestive tract morphogenesis GO:0048546 56 0.043
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.042
cellular carbohydrate metabolic process GO:0044262 84 0.042
positive regulation of t cell activation GO:0050870 54 0.042
regulation of translation GO:0006417 89 0.042
response to hyperoxia GO:0055093 4 0.042
canonical wnt signaling pathway GO:0060070 116 0.042
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.042
segmentation GO:0035282 4 0.041
negative regulation of protein phosphorylation GO:0001933 140 0.041
wound healing GO:0042060 115 0.041
Human
growth GO:0040007 202 0.041
Human
regulation of striated muscle tissue development GO:0016202 26 0.041
regulation of cytokine production GO:0001817 232 0.041
Human
female gamete generation GO:0007292 2 0.041
epithelial to mesenchymal transition GO:0001837 48 0.040
single organismal cell cell adhesion GO:0016337 148 0.040
Human
regulation of leukocyte proliferation GO:0070663 67 0.040
positive regulation of mononuclear cell proliferation GO:0032946 47 0.040
response to lipid GO:0033993 206 0.040
Human
bone development GO:0060348 26 0.040
epithelial cell proliferation GO:0050673 128 0.039
protein processing GO:0016485 226 0.039
regulation of protein localization GO:0032880 296 0.039
Human
response to radiation GO:0009314 151 0.038
posttranscriptional regulation of gene expression GO:0010608 213 0.038
signal transduction by phosphorylation GO:0023014 297 0.038
Human
pharyngeal system development GO:0060037 2 0.037
chemical homeostasis GO:0048878 306 0.037
cytoplasmic transport GO:0016482 379 0.037
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.037
Human
plasma membrane organization GO:0007009 115 0.037
regulation of t cell activation GO:0050863 77 0.036
neuromuscular junction development GO:0007528 3 0.036
single organism cellular localization GO:1902580 332 0.036
positive regulation of protein phosphorylation GO:0001934 313 0.036
Human
oxidation reduction process GO:0055114 396 0.036
regulation of lymphocyte proliferation GO:0050670 64 0.036
stem cell development GO:0048864 69 0.035
system process GO:0003008 349 0.035
positive regulation of myoblast differentiation GO:0045663 6 0.035
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 1 0.035
motor neuron axon guidance GO:0008045 2 0.035
positive regulation of cell activation GO:0050867 81 0.035
regulation of response to external stimulus GO:0032101 222 0.034
Human
stem cell differentiation GO:0048863 93 0.034
collagen fibril organization GO:0030199 10 0.034
sensory perception of sound GO:0007605 37 0.034
epithelium migration GO:0090132 119 0.033
Human
circulatory system process GO:0003013 113 0.033
endoderm development GO:0007492 33 0.033
morphogenesis of embryonic epithelium GO:0016331 4 0.033
muscle tissue development GO:0060537 62 0.033
type b pancreatic cell proliferation GO:0044342 0 0.031
morphogenesis of an epithelial sheet GO:0002011 12 0.031
Human
positive regulation of transferase activity GO:0051347 227 0.031
Human
cellular macromolecule catabolic process GO:0044265 380 0.031
single organism membrane organization GO:0044802 268 0.030
glycoprotein metabolic process GO:0009100 110 0.030
regulation of ion transport GO:0043269 189 0.029
sensory perception of light stimulus GO:0050953 35 0.029
regulation of mononuclear cell proliferation GO:0032944 65 0.029
response to inorganic substance GO:0010035 127 0.029
Human
skin morphogenesis GO:0043589 6 0.029
regulation of transferase activity GO:0051338 355 0.029
Human
cellular amine metabolic process GO:0044106 41 0.029
dermatome development GO:0061054 3 0.029
leukocyte proliferation GO:0070661 74 0.028
negative regulation of cell adhesion GO:0007162 64 0.028
Human
myeloid cell differentiation GO:0030099 117 0.028
integrin biosynthetic process GO:0045112 4 0.028
blastoderm segmentation GO:0007350 2 0.028
negative regulation of immune response GO:0050777 40 0.028
embryonic forelimb morphogenesis GO:0035115 4 0.028
vasculature development GO:0001944 181 0.028
positive regulation of wnt signaling pathway GO:0030177 54 0.028
protein targeting GO:0006605 187 0.028
negative regulation of cell motility GO:2000146 104 0.027
Human
canonical wnt signaling pathway involved in osteoblast differentiation GO:0044339 2 0.027
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.027
Human
blood circulation GO:0008015 113 0.027
regulation of cellular amine metabolic process GO:0033238 11 0.027
cellular response to lipid GO:0071396 127 0.027
Human
epithelial cell migration GO:0010631 119 0.027
Human
activin receptor signaling pathway GO:0032924 24 0.027
oogenesis GO:0048477 2 0.027
regulation of t cell proliferation GO:0042129 42 0.026
regulation of cell cell adhesion GO:0022407 57 0.026
apoptotic signaling pathway GO:0097190 268 0.026
neural crest cell development GO:0014032 3 0.026
regulation of myoblast differentiation GO:0045661 12 0.026
regulation of carbohydrate metabolic process GO:0006109 54 0.026
positive regulation of kinase activity GO:0033674 204 0.026
Human
cell chemotaxis GO:0060326 112 0.026
Human
positive regulation of cell adhesion GO:0045785 84 0.025
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.025
response to mechanical stimulus GO:0009612 51 0.025
regulation of kinase activity GO:0043549 314 0.025
Human
mononuclear cell proliferation GO:0032943 71 0.024
positive regulation of hydrolase activity GO:0051345 331 0.024
regulation of ossification GO:0030278 58 0.024
negative regulation of smooth muscle cell proliferation GO:0048662 14 0.024
regulation of dermatome development GO:0061183 3 0.024
muscle organ development GO:0007517 56 0.024
angiogenesis GO:0001525 147 0.024
heart development GO:0007507 95 0.024
ribonucleoside triphosphate catabolic process GO:0009203 391 0.024
embryonic epithelial tube formation GO:0001838 4 0.024
positive regulation of muscle cell differentiation GO:0051149 15 0.024
regulation of cellular response to stress GO:0080135 244 0.024
locomotory behavior GO:0007626 1 0.024
hexose metabolic process GO:0019318 55 0.023
ribonucleoside catabolic process GO:0042454 406 0.023
purine nucleoside triphosphate metabolic process GO:0009144 412 0.023
negative regulation of intracellular signal transduction GO:1902532 183 0.023
negative regulation of catalytic activity GO:0043086 335 0.023
hindbrain development GO:0030902 3 0.023
positive regulation of transport GO:0051050 336 0.023
Human
glial cell migration GO:0008347 4 0.023
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 2 0.023
nucleotide catabolic process GO:0009166 408 0.023
purine nucleotide catabolic process GO:0006195 405 0.023
amine metabolic process GO:0009308 44 0.023
purine ribonucleoside metabolic process GO:0046128 437 0.023
skeletal muscle fiber development GO:0048741 12 0.023
response to oxidative stress GO:0006979 121 0.023
Human
glucose metabolic process GO:0006006 45 0.023
regulation of gastrulation GO:0010470 12 0.023
endochondral bone morphogenesis GO:0060350 3 0.023
hematopoietic or lymphoid organ development GO:0048534 186 0.022
insulin like growth factor receptor signaling pathway GO:0048009 13 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.022
response to metal ion GO:0010038 84 0.022
Human
forelimb morphogenesis GO:0035136 4 0.022
regulation of intracellular transport GO:0032386 195 0.022
muscle fiber development GO:0048747 16 0.022
nervous system development GO:0007399 293 0.022
ribonucleoside triphosphate metabolic process GO:0009199 412 0.022
cellular response to dna damage stimulus GO:0006974 379 0.022
cell projection organization GO:0030030 252 0.022
regulation of glucose metabolic process GO:0010906 28 0.021
purine nucleoside catabolic process GO:0006152 398 0.021
positive regulation of nucleotide metabolic process GO:0045981 230 0.021
lymphocyte activation GO:0046649 133 0.021
determination of adult lifespan GO:0008340 2 0.021
nucleoside phosphate catabolic process GO:1901292 412 0.021
cellular ketone metabolic process GO:0042180 80 0.021
cell projection morphogenesis GO:0048858 129 0.021
regulation of cellular ketone metabolic process GO:0010565 50 0.021
regulation of sodium dependent phosphate transport GO:2000118 2 0.021
sequestering of metal ion GO:0051238 24 0.021
single organism reproductive process GO:0044702 98 0.021
gtp catabolic process GO:0006184 237 0.021
guanosine containing compound catabolic process GO:1901069 239 0.021
purine ribonucleoside catabolic process GO:0046130 398 0.021
response to drug GO:0042493 81 0.021
positive regulation of stem cell differentiation GO:2000738 29 0.021
t cell activation GO:0042110 99 0.020
regulation of cellular response to growth factor stimulus GO:0090287 76 0.020
Human
cartilage development involved in endochondral bone morphogenesis GO:0060351 2 0.020
organophosphate catabolic process GO:0046434 430 0.020
trabecula morphogenesis GO:0061383 2 0.020
glycosyl compound catabolic process GO:1901658 413 0.020
intracellular protein transport GO:0006886 270 0.020
multicellular organismal aging GO:0010259 3 0.020
cellular response to interleukin 1 GO:0071347 35 0.020
smooth muscle cell migration GO:0014909 18 0.020
neurological system process GO:0050877 163 0.020
positive regulation of membrane protein ectodomain proteolysis GO:0051044 13 0.020
regulation of nucleotide metabolic process GO:0006140 269 0.020
regulation of epithelial cell proliferation GO:0050678 113 0.020
chondrocyte development GO:0002063 1 0.020
nucleoside triphosphate metabolic process GO:0009141 422 0.020
regulation of transmembrane transport GO:0034762 139 0.019
ion transmembrane transport GO:0034220 338 0.019
eye development GO:0001654 42 0.019
rhythmic behavior GO:0007622 2 0.019
endothelial cell migration GO:0043542 86 0.019
erk1 and erk2 cascade GO:0070371 104 0.019
t cell proliferation GO:0042098 45 0.019
anterior posterior axis specification embryo GO:0008595 2 0.019
epidermis development GO:0008544 59 0.019
Human
regulation of cytoplasmic transport GO:1903649 149 0.019
mapk cascade GO:0000165 288 0.019
Human
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.019
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.019
wound healing spreading of cells GO:0044319 8 0.019
Human
regulation of apoptotic signaling pathway GO:2001233 175 0.019
regulation of myotube differentiation GO:0010830 18 0.019
cartilage condensation GO:0001502 1 0.019
carbohydrate derivative biosynthetic process GO:1901137 207 0.019
embryonic organ development GO:0048568 36 0.019
negative regulation of cell substrate adhesion GO:0010812 24 0.019
Human
cellular response to abiotic stimulus GO:0071214 117 0.018
cellular protein catabolic process GO:0044257 261 0.018
morphogenesis of a polarized epithelium GO:0001738 3 0.018
taxis GO:0042330 157 0.018
Human
collagen biosynthetic process GO:0032964 15 0.018
positive regulation of plasminogen activation GO:0010756 3 0.018
regulation of actin filament based process GO:0032970 141 0.018
positive regulation of epidermis development GO:0045684 11 0.018
negative regulation of transport GO:0051051 176 0.018
anterior posterior axis specification GO:0009948 2 0.018
reactive oxygen species metabolic process GO:0072593 75 0.018
lipid metabolic process GO:0006629 381 0.018
maintenance of location GO:0051235 112 0.018
detection of abiotic stimulus GO:0009582 15 0.018
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.018
sequestering of calcium ion GO:0051208 17 0.018
negative regulation of programmed cell death GO:0043069 321 0.018
cation homeostasis GO:0055080 189 0.018
positive regulation of ras gtpase activity GO:0032320 117 0.018
muscle cell proliferation GO:0033002 35 0.018
dephosphorylation GO:0016311 209 0.018
secretion by cell GO:0032940 226 0.018
Human
peptidyl tyrosine phosphorylation GO:0018108 170 0.018
Human
regulation of protein serine threonine kinase activity GO:0071900 179 0.018
Human
sensory perception of mechanical stimulus GO:0050954 37 0.018
guanosine containing compound metabolic process GO:1901068 244 0.018
replacement ossification GO:0036075 1 0.018
oocyte differentiation GO:0009994 2 0.018
negative regulation of cellular amine metabolic process GO:0033239 3 0.018
defense response GO:0006952 315 0.018
Human
negative regulation of hydrolase activity GO:0051346 182 0.018
peptide cross linking GO:0018149 12 0.018
regulation of osteoblast differentiation GO:0045667 38 0.018
regulation of blood pressure GO:0008217 30 0.018
regulation of gtpase activity GO:0043087 180 0.018
hematopoietic progenitor cell differentiation GO:0002244 38 0.018
regulation of response to wounding GO:1903034 101 0.018
purine ribonucleotide catabolic process GO:0009154 404 0.018
regulation of angiogenesis GO:0045765 92 0.018
positive regulation of gtpase activity GO:0043547 166 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
embryonic viscerocranium morphogenesis GO:0048703 1 0.017
negative regulation of growth GO:0045926 97 0.017
Human
positive regulation of protein kinase activity GO:0045860 190 0.017
Human
neural tube formation GO:0001841 3 0.017
response to alcohol GO:0097305 64 0.017
negative regulation of cell cycle GO:0045786 193 0.017
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.017
connective tissue development GO:0061448 39 0.017
head development GO:0060322 108 0.017
neuron projection regeneration GO:0031102 1 0.017
cardiac muscle cell contraction GO:0086003 4 0.017
regulation of protein kinase activity GO:0045859 289 0.017
Human
ion homeostasis GO:0050801 230 0.016
negative regulation of hydrogen peroxide metabolic process GO:0010727 3 0.016
oocyte development GO:0048599 1 0.016
positive regulation of epithelial cell migration GO:0010634 55 0.016
Human
tissue migration GO:0090130 119 0.016
Human
nucleoside triphosphate catabolic process GO:0009143 394 0.016
primary neural tube formation GO:0014020 3 0.016
regulation of gtp catabolic process GO:0033124 180 0.016
regulation of cell substrate adhesion GO:0010810 68 0.016
Human
regulation of protein import into nucleus GO:0042306 78 0.016
negative regulation of reactive oxygen species metabolic process GO:2000378 11 0.016
histone modification GO:0016570 251 0.016
covalent chromatin modification GO:0016569 254 0.016
purine containing compound catabolic process GO:0072523 411 0.016
response to bacterium GO:0009617 144 0.016
Human
neural tube closure GO:0001843 3 0.016
positive regulation of cell development GO:0010720 92 0.016
negative regulation of cellular response to hepatocyte growth factor stimulus GO:2001113 1 0.016
central nervous system development GO:0007417 123 0.016
tripartite regional subdivision GO:0007351 2 0.016
cellular response to metal ion GO:0071248 43 0.016
circadian behavior GO:0048512 2 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.016
cellular ion homeostasis GO:0006873 168 0.016
salivary gland morphogenesis GO:0007435 4 0.016
regulation of embryonic development GO:0045995 20 0.016
embryonic skeletal system morphogenesis GO:0048704 9 0.016
generation of neurons GO:0048699 152 0.016
negative regulation of myeloid cell differentiation GO:0045638 42 0.015
mitotic cell cycle GO:0000278 326 0.015
Human
positive regulation of fibroblast migration GO:0010763 3 0.015
protein maturation GO:0051604 233 0.015
negative regulation of apoptotic process GO:0043066 316 0.015

ADAM12 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.245
bone development disease DOID:0080006 55 0.126
bone disease DOID:0080001 88 0.126
connective tissue disease DOID:65 109 0.126
osteochondrodysplasia DOID:2256 35 0.043
sensory system disease DOID:0050155 203 0.028
Human
nervous system disease DOID:863 431 0.028
Human
ehlers danlos syndrome DOID:13359 9 0.021
collagen disease DOID:854 9 0.021
eye and adnexa disease DOID:1492 150 0.020
Human
eye disease DOID:5614 149 0.020
Human
osteogenesis imperfecta DOID:12347 13 0.018
disease of metabolism DOID:0014667 295 0.017
central nervous system disease DOID:331 186 0.016