Homo sapiens

72 known processes

ADAM15

ADAM metallopeptidase domain 15

(Aliases: MDC15)

ADAM15 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
membrane protein proteolysis GO:0033619 38 1.000
Human
membrane protein ectodomain proteolysis GO:0006509 33 0.998
Human
membrane tubulation GO:0097320 12 0.976
regulation of transferase activity GO:0051338 355 0.954
Human
positive regulation of membrane protein ectodomain proteolysis GO:0051044 13 0.952
macropinocytosis GO:0044351 1 0.939
positive regulation of protein catabolic process GO:0045732 75 0.928
early endosome to golgi transport GO:0034498 3 0.910
cation transport GO:0006812 331 0.900
positive regulation of cellular amine metabolic process GO:0033240 7 0.899
positive regulation of kinase activity GO:0033674 204 0.891
Human
positive regulation of protein kinase activity GO:0045860 190 0.890
Human
pinocytosis GO:0006907 8 0.889
regulation of protein kinase activity GO:0045859 289 0.887
Human
regulation of protein catabolic process GO:0042176 155 0.862
metal ion transport GO:0030001 272 0.861
guanosine containing compound catabolic process GO:1901069 239 0.858
salivary gland morphogenesis GO:0007435 4 0.853
positive regulation of phosphorylation GO:0042327 394 0.853
Human
cellular ketone metabolic process GO:0042180 80 0.835
regulation of cellular amine metabolic process GO:0033238 11 0.830
intracellular protein transport GO:0006886 270 0.812
peptidyl tyrosine phosphorylation GO:0018108 170 0.811
Human
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.801
regulation of membrane protein ectodomain proteolysis GO:0051043 17 0.799
nucleotide catabolic process GO:0009166 408 0.792
defense response GO:0006952 315 0.785
regulation of kinase activity GO:0043549 314 0.781
Human
positive regulation of transferase activity GO:0051347 227 0.780
Human
endosome organization GO:0007032 20 0.774
positive regulation of protein phosphorylation GO:0001934 313 0.767
Human
single organism membrane organization GO:0044802 268 0.765
cellular amino acid metabolic process GO:0006520 116 0.745
purine nucleoside catabolic process GO:0006152 398 0.739
regulation of epithelial cell migration GO:0010632 93 0.730
cellular amine metabolic process GO:0044106 41 0.695
negative regulation of transport GO:0051051 176 0.688
regulation of nucleoside metabolic process GO:0009118 209 0.656
peptidyl tyrosine modification GO:0018212 170 0.651
Human
positive regulation of cellular component organization GO:0051130 376 0.649
membrane organization GO:0061024 292 0.646
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.642
positive regulation of protein oligomerization GO:0032461 17 0.609
regulation of purine nucleotide catabolic process GO:0033121 205 0.608
single organism cell adhesion GO:0098602 179 0.606
regulation of proteolysis GO:0030162 293 0.604
negative regulation of cellular protein metabolic process GO:0032269 353 0.590
skeletal system development GO:0001501 79 0.588
positive regulation of catabolic process GO:0009896 310 0.577
negative regulation of protein metabolic process GO:0051248 391 0.574
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway GO:0035625 4 0.569
Human
protein catabolic process GO:0030163 325 0.549
positive regulation of proteolysis GO:0045862 142 0.548
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.548
Human
immunoglobulin biosynthetic process GO:0002378 2 0.543
mitotic cell cycle process GO:1903047 286 0.539
Human
gtp catabolic process GO:0006184 237 0.526
cardiovascular system development GO:0072358 262 0.525
Mouse
regulation of cellular ketone metabolic process GO:0010565 50 0.520
single organismal cell cell adhesion GO:0016337 148 0.519
regulation of protein localization GO:0032880 296 0.513
circulatory system development GO:0072359 262 0.507
Mouse
gtp metabolic process GO:0046039 239 0.495
adherens junction organization GO:0034332 36 0.495
cytoplasmic transport GO:0016482 379 0.492
epithelium development GO:0060429 227 0.491
Human
ribonucleoside catabolic process GO:0042454 406 0.487
immune response GO:0006955 307 0.486
regulation of cellular component biogenesis GO:0044087 281 0.472
retrograde transport endosome to golgi GO:0042147 45 0.456
negative regulation of protein maturation GO:1903318 142 0.433
carbohydrate metabolic process GO:0005975 207 0.432
response to oxygen containing compound GO:1901700 369 0.430
Human
positive regulation of lipid metabolic process GO:0045834 50 0.423
regulation of endocytosis GO:0030100 72 0.417
lipid tube assembly GO:0060988 2 0.414
purine containing compound catabolic process GO:0072523 411 0.410
positive regulation of gtp catabolic process GO:0033126 166 0.408
protein localization to organelle GO:0033365 280 0.404
mitotic cytokinesis GO:0000281 19 0.394
monovalent inorganic cation transport GO:0015672 128 0.391
purine nucleoside triphosphate catabolic process GO:0009146 392 0.382
regulation of vesicle mediated transport GO:0060627 130 0.380
purine nucleotide catabolic process GO:0006195 405 0.379
modification dependent protein catabolic process GO:0019941 209 0.377
negative regulation of ion transport GO:0043271 39 0.370
glycosyl compound catabolic process GO:1901658 413 0.369
positive regulation of protein localization to cell surface GO:2000010 6 0.368
nucleoside triphosphate metabolic process GO:0009141 422 0.366
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.349
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.346
cellular lipid metabolic process GO:0044255 303 0.336
protein modification by small protein conjugation GO:0032446 342 0.336
reactive oxygen species metabolic process GO:0072593 75 0.331
superoxide metabolic process GO:0006801 20 0.330
leukocyte activation GO:0045321 164 0.328
positive regulation of gtpase activity GO:0043547 166 0.323
response to other organism GO:0051707 261 0.320
Human
lymphocyte activation GO:0046649 133 0.318
biological adhesion GO:0022610 331 0.318
calcium ion transport GO:0006816 147 0.315
regulation of homeostatic process GO:0032844 121 0.310
dephosphorylation GO:0016311 209 0.307
oxidation reduction process GO:0055114 396 0.291
regulation of calcium ion transport GO:0051924 79 0.288
positive regulation of nucleotide catabolic process GO:0030813 185 0.284
purine ribonucleotide catabolic process GO:0009154 404 0.276
protein lipid complex subunit organization GO:0071825 24 0.273
mitotic cell cycle GO:0000278 326 0.272
Human
plasma membrane organization GO:0007009 115 0.269
negative regulation of catalytic activity GO:0043086 335 0.264
positive regulation of nucleotide metabolic process GO:0045981 230 0.254
protein oligomerization GO:0051259 173 0.250
protein dephosphorylation GO:0006470 81 0.250
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.249
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.247
Human
immune system development GO:0002520 195 0.240
ion homeostasis GO:0050801 230 0.239
regulation of intracellular transport GO:0032386 195 0.238
stress activated mapk cascade GO:0051403 93 0.238
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.234
Human
activation of protein kinase activity GO:0032147 90 0.230
negative regulation of phosphorus metabolic process GO:0010563 267 0.229
nucleoside catabolic process GO:0009164 408 0.229
response to nitrogen compound GO:1901698 184 0.229
glycerolipid metabolic process GO:0046486 107 0.228
cell cycle phase transition GO:0044770 173 0.227
Human
lipid biosynthetic process GO:0008610 177 0.225
regulation of gtpase activity GO:0043087 180 0.220
nucleoside triphosphate catabolic process GO:0009143 394 0.219
protein processing GO:0016485 226 0.212
protein import GO:0017038 130 0.209
endosomal transport GO:0016197 129 0.209
nitrogen compound transport GO:0071705 191 0.205
ubiquitin dependent protein catabolic process GO:0006511 206 0.195
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.194
regulation of purine nucleotide metabolic process GO:1900542 264 0.192
mitotic cell cycle phase transition GO:0044772 162 0.191
Human
regulation of metal ion transport GO:0010959 120 0.188
positive regulation of cellular catabolic process GO:0031331 284 0.187
negative regulation of phosphate metabolic process GO:0045936 267 0.182
spermatid development GO:0007286 4 0.181
response to organonitrogen compound GO:0010243 156 0.181
negative regulation of proteolysis GO:0045861 132 0.180
protein targeting GO:0006605 187 0.177
epithelium migration GO:0090132 119 0.177
regulation of protein oligomerization GO:0032459 26 0.176
adenylate cyclase inhibiting adrenergic receptor signaling pathway GO:0071881 1 0.174
regulation of immune response GO:0050776 201 0.170
regulation of nucleotide metabolic process GO:0006140 269 0.169
antigen receptor mediated signaling pathway GO:0050851 38 0.168
endothelial cell migration GO:0043542 86 0.168
regulation of actin cytoskeleton organization GO:0032956 116 0.165
protein localization to cell surface GO:0034394 28 0.162
regulation of osteoblast differentiation GO:0045667 38 0.161
regulation of nucleotide catabolic process GO:0030811 205 0.160
t cell receptor signaling pathway GO:0050852 21 0.159
negative regulation of cell proliferation GO:0008285 228 0.159
nucleocytoplasmic transport GO:0006913 176 0.158
chemical homeostasis GO:0048878 306 0.155
negative regulation of phosphorylation GO:0042326 174 0.154
regulation of synaptic plasticity GO:0048167 3 0.153
cellular response to endogenous stimulus GO:0071495 336 0.152
Human
regulation of gtp catabolic process GO:0033124 180 0.150
response to lipid GO:0033993 206 0.149
Human
cleavage furrow formation GO:0036089 5 0.149
vesicle mediated transport GO:0016192 371 0.148
regulation of ion transport GO:0043269 189 0.145
negative regulation of protein localization to cell surface GO:2000009 5 0.145
endomembrane system organization GO:0010256 196 0.145
mapk cascade GO:0000165 288 0.143
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.142
erk1 and erk2 cascade GO:0070371 104 0.141
cell competition in a multicellular organism GO:0035212 1 0.139
regulation of cell cell adhesion GO:0022407 57 0.139
cellular response to oxygen containing compound GO:1901701 276 0.138
positive regulation of leukocyte activation GO:0002696 80 0.135
negative regulation of developmental process GO:0051093 247 0.135
modification dependent macromolecule catabolic process GO:0043632 212 0.133
sensory organ development GO:0007423 52 0.132
regulation of t cell activation GO:0050863 77 0.131
multicellular organismal homeostasis GO:0048871 67 0.128
protein maturation GO:0051604 233 0.127
negative regulation of protein processing GO:0010955 142 0.126
bone development GO:0060348 26 0.126
regulation of cgmp mediated signaling GO:0010752 1 0.121
oogenesis GO:0048477 2 0.119
positive regulation of intracellular protein transport GO:0090316 76 0.119
cell chemotaxis GO:0060326 112 0.116
Human
phagosome lysosome fusion GO:0090385 4 0.116
regulation of protein localization to cell surface GO:2000008 15 0.115
cellular protein catabolic process GO:0044257 261 0.115
negative regulation of immune system process GO:0002683 136 0.114
positive regulation of endothelial cell migration GO:0010595 39 0.114
positive regulation of cellular component biogenesis GO:0044089 158 0.110
negative regulation of endocytosis GO:0045806 19 0.109
positive regulation of phosphatidylinositol biosynthetic process GO:0010513 3 0.109
alcohol metabolic process GO:0006066 114 0.107
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.107
Human
regulation of cellular amino acid metabolic process GO:0006521 6 0.107
oocyte development GO:0048599 1 0.107
mitochondrion organization GO:0007005 156 0.106
regulation of peptidase activity GO:0052547 180 0.105
spermatid differentiation GO:0048515 4 0.105
amine metabolic process GO:0009308 44 0.104
protein lipid complex assembly GO:0065005 12 0.103
regulation of potassium ion transport GO:0043266 24 0.103
divalent metal ion transport GO:0070838 152 0.102
lipid metabolic process GO:0006629 381 0.101
phospholipid metabolic process GO:0006644 99 0.100
epithelial cell development GO:0002064 34 0.100
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.097
positive regulation of cell adhesion GO:0045785 84 0.096
ribonucleoside triphosphate catabolic process GO:0009203 391 0.096
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.095
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.095
regulation of lymphocyte activation GO:0051249 103 0.095
oocyte differentiation GO:0009994 2 0.094
regulation of cell projection organization GO:0031344 107 0.094
positive regulation of cell proliferation GO:0008284 301 0.093
Human
peptidyl tyrosine dephosphorylation GO:0035335 36 0.091
regulation of cellular component movement GO:0051270 334 0.090
regulation of protein processing GO:0070613 150 0.089
regulation of mapk cascade GO:0043408 262 0.089
ribonucleoside triphosphate metabolic process GO:0009199 412 0.088
nucleoside phosphate biosynthetic process GO:1901293 109 0.086
signal transduction by phosphorylation GO:0023014 297 0.085
positive regulation of organelle organization GO:0010638 195 0.085
heart development GO:0007507 95 0.085
Mouse
negative regulation of cellular component organization GO:0051129 235 0.084
cellular carbohydrate metabolic process GO:0044262 84 0.084
positive regulation of mapk cascade GO:0043410 190 0.084
ribonucleotide catabolic process GO:0009261 405 0.083
regulation of ion homeostasis GO:2000021 73 0.083
tissue migration GO:0090130 119 0.083
positive regulation of transport GO:0051050 336 0.083
sequestering of metal ion GO:0051238 24 0.082
microtubule cytoskeleton organization GO:0000226 176 0.082
neuron development GO:0048666 113 0.082
cellular response to lipid GO:0071396 127 0.081
negative regulation of protein kinase activity GO:0006469 98 0.080
negative regulation of intracellular signal transduction GO:1902532 183 0.080
single organism cellular localization GO:1902580 332 0.079
small gtpase mediated signal transduction GO:0007264 78 0.079
regulation of cell differentiation GO:0045595 393 0.079
small molecule biosynthetic process GO:0044283 157 0.079
female gamete generation GO:0007292 2 0.079
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.078
Human
endocytosis GO:0006897 159 0.078
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.078
positive regulation of neurogenesis GO:0050769 49 0.077
regulation of nucleotide biosynthetic process GO:0030808 50 0.077
organ morphogenesis GO:0009887 147 0.077
Mouse
reactive oxygen species biosynthetic process GO:1903409 4 0.076
extracellular structure organization GO:0043062 41 0.076
vasculature development GO:0001944 181 0.076
response to hormone GO:0009725 175 0.075
regulation of protein serine threonine kinase activity GO:0071900 179 0.074
Human
organonitrogen compound biosynthetic process GO:1901566 200 0.072
metal ion homeostasis GO:0055065 169 0.072
tissue morphogenesis GO:0048729 96 0.071
Human
positive regulation of nervous system development GO:0051962 54 0.070
regulation of blood vessel size GO:0050880 18 0.070
negative regulation of cell death GO:0060548 345 0.070
reactive nitrogen species metabolic process GO:2001057 3 0.070
stress activated protein kinase signaling cascade GO:0031098 94 0.070
cell cell junction organization GO:0045216 69 0.070
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.069
lymphocyte proliferation GO:0046651 70 0.069
negative regulation of cellular amine metabolic process GO:0033239 3 0.069
response to organic cyclic compound GO:0014070 204 0.068
leukocyte proliferation GO:0070661 74 0.068
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.067
reproductive process GO:0022414 106 0.067
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.067
cytoskeleton dependent cytokinesis GO:0061640 22 0.067
negative regulation of cell adhesion GO:0007162 64 0.066
regulation of cell adhesion mediated by integrin GO:0033628 22 0.066
regulation of secretion GO:0051046 194 0.066
regulation of anatomical structure morphogenesis GO:0022603 286 0.064
cell morphogenesis involved in differentiation GO:0000904 144 0.064
Mouse
cellular homeostasis GO:0019725 196 0.064
golgi vesicle transport GO:0048193 80 0.063
negative regulation of kinase activity GO:0033673 106 0.063
cell division GO:0051301 168 0.063
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.063
mononuclear cell proliferation GO:0032943 71 0.063
protein autophosphorylation GO:0046777 123 0.063
morphogenesis of an epithelium GO:0002009 60 0.063
Human
positive regulation of protein complex assembly GO:0031334 86 0.063
negative regulation of growth GO:0045926 97 0.062
regulation of membrane potential GO:0042391 95 0.062
vesicle fusion GO:0006906 17 0.062
purine ribonucleoside catabolic process GO:0046130 398 0.062
liposaccharide metabolic process GO:1903509 27 0.061
multicellular organismal reproductive process GO:0048609 40 0.060
jnk cascade GO:0007254 80 0.060
azole transport GO:0045117 4 0.060
regulation of protein maturation GO:1903317 150 0.060
anatomical structure formation involved in morphogenesis GO:0048646 284 0.060
cellular response to nitrogen compound GO:1901699 144 0.059
receptor mediated endocytosis GO:0006898 84 0.059
cellular macromolecular complex assembly GO:0034622 324 0.059
cytokinesis GO:0000910 96 0.059
purine ribonucleotide biosynthetic process GO:0009152 79 0.059
membrane lipid metabolic process GO:0006643 53 0.058
canonical wnt signaling pathway GO:0060070 116 0.057
positive regulation of lipid kinase activity GO:0090218 13 0.057
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 20 0.057
immune response activating signal transduction GO:0002757 90 0.057
taxis GO:0042330 157 0.056
Human
single organism carbohydrate metabolic process GO:0044723 193 0.056
organelle assembly GO:0070925 176 0.056
organic hydroxy compound metabolic process GO:1901615 147 0.056
segmentation GO:0035282 4 0.055
regulation of leukocyte proliferation GO:0070663 67 0.055
trivalent inorganic cation transport GO:0072512 4 0.055
protein ubiquitination GO:0016567 314 0.054
activation of immune response GO:0002253 114 0.054
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.054
cell projection organization GO:0030030 252 0.054
memory GO:0007613 3 0.053
transmembrane transport GO:0055085 399 0.053
cellular response to growth factor stimulus GO:0071363 197 0.052
Human
regulation of protein transport GO:0051223 213 0.052
regulation of protein ubiquitination GO:0031396 95 0.051
regulation of cytoplasmic transport GO:1903649 149 0.051
purine ribonucleoside metabolic process GO:0046128 437 0.050
membrane fusion GO:0061025 43 0.050
i kappab kinase nf kappab signaling GO:0007249 166 0.050
regulation of macrophage chemotaxis GO:0010758 4 0.049
superoxide anion generation GO:0042554 11 0.049
response to peptide GO:1901652 65 0.049
response to oxygen levels GO:0070482 100 0.049
Human
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.049
activation of mapk activity by adrenergic receptor signaling pathway GO:0071883 3 0.049
stress fiber assembly GO:0043149 40 0.049
regulation of cell adhesion GO:0030155 166 0.048
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.048
positive regulation of cytoplasmic transport GO:1903651 82 0.048
response to cytokine GO:0034097 232 0.048
system process GO:0003008 349 0.048
divalent inorganic cation transport GO:0072511 158 0.048
extracellular matrix organization GO:0030198 41 0.048
potassium ion transport GO:0006813 62 0.048
regulation of receptor mediated endocytosis GO:0048259 32 0.048
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 15 0.047
Human
actin filament organization GO:0007015 128 0.047
positive regulation of cellular component movement GO:0051272 181 0.047
Human
regulation of protein import into nucleus GO:0042306 78 0.047
t cell activation GO:0042110 99 0.046
maintenance of cell polarity GO:0030011 2 0.046
ras protein signal transduction GO:0007265 73 0.046
ion transmembrane transport GO:0034220 338 0.046
cyclic nucleotide biosynthetic process GO:0009190 61 0.046
cellular cation homeostasis GO:0030003 163 0.045
regulation of wnt signaling pathway GO:0030111 123 0.045
innate immune response GO:0045087 178 0.045
establishment of protein localization to membrane GO:0090150 121 0.045
response to monosaccharide GO:0034284 20 0.045
regulation of glial cell proliferation GO:0060251 4 0.045
regulation of cell growth GO:0001558 135 0.045
oocyte maturation GO:0001556 1 0.045
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.044
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.044
regulation of clathrin mediated endocytosis GO:2000369 4 0.044
regulation of platelet aggregation GO:0090330 4 0.044
neuron differentiation GO:0030182 138 0.044
positive regulation of cell activation GO:0050867 81 0.044
peptide transport GO:0015833 74 0.044
positive regulation of cell growth GO:0030307 48 0.044
Human
cellular response to organic cyclic compound GO:0071407 127 0.043
positive regulation of nucleoside metabolic process GO:0045979 186 0.043
negative regulation of protein modification process GO:0031400 200 0.043
regulation of mononuclear cell proliferation GO:0032944 65 0.043
determination of adult lifespan GO:0008340 2 0.043
negative regulation of calcium ion transport GO:0051926 19 0.042
embryo development GO:0009790 123 0.042
regulation of establishment of protein localization GO:0070201 242 0.042
regulation of erk1 and erk2 cascade GO:0070372 99 0.042
positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 11 0.042
Human
secretion GO:0046903 254 0.042
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.041
Human
positive regulation of monooxygenase activity GO:0032770 14 0.041
negative regulation of protein phosphorylation GO:0001933 140 0.041
regulation of postsynaptic membrane potential GO:0060078 1 0.041
negative regulation of protein catabolic process GO:0042177 59 0.041
negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179 1 0.041
nucleotide biosynthetic process GO:0009165 109 0.041
positive regulation of neuron differentiation GO:0045666 40 0.041
cell adhesion GO:0007155 325 0.040
tripartite regional subdivision GO:0007351 2 0.040
caveola assembly GO:0070836 4 0.040
carbohydrate derivative biosynthetic process GO:1901137 207 0.040
secretion by cell GO:0032940 226 0.040
cell activation GO:0001775 213 0.040
response to hydrogen peroxide GO:0042542 40 0.039
phagolysosome assembly GO:0001845 5 0.039
sterol transport GO:0015918 39 0.039
regulation of neuron differentiation GO:0045664 70 0.039
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.039
multi organism reproductive process GO:0044703 54 0.039
developmental process involved in reproduction GO:0003006 66 0.039
cellular response to peptide hormone stimulus GO:0071375 56 0.039
regulation of leukocyte activation GO:0002694 115 0.038
negative regulation of alpha beta t cell proliferation GO:0046642 1 0.038
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.038
Human
post embryonic development GO:0009791 2 0.038
release of sequestered calcium ion into cytosol GO:0051209 41 0.038
microtubule based process GO:0007017 210 0.037
positive regulation of ras gtpase activity GO:0032320 117 0.037
regulation of anatomical structure size GO:0090066 101 0.037
vasodilation GO:0042311 4 0.037
divalent inorganic cation homeostasis GO:0072507 136 0.037
regulation of cell motility GO:2000145 299 0.037
establishment of protein localization to organelle GO:0072594 172 0.037
regulation of cell substrate adhesion GO:0010810 68 0.037
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.037
negative regulation of cell cell adhesion GO:0022408 27 0.036
epithelial cell migration GO:0010631 119 0.036
regulation of defense response GO:0031347 154 0.036
wound healing GO:0042060 115 0.036
Human Rat
regulation of peptide transport GO:0090087 62 0.035
ribose phosphate biosynthetic process GO:0046390 82 0.035
positive regulation of developmental process GO:0051094 314 0.035
tissue homeostasis GO:0001894 63 0.035
response to tumor necrosis factor GO:0034612 76 0.034
regulation of inositol phosphate biosynthetic process GO:0010919 3 0.034
response to mechanical stimulus GO:0009612 51 0.034
negative regulation of mapk cascade GO:0043409 56 0.034
response to growth factor GO:0070848 205 0.034
Human
actin filament based process GO:0030029 224 0.034
ameboidal type cell migration GO:0001667 135 0.033
negative regulation of phosphatase activity GO:0010923 61 0.033
positive regulation of cell differentiation GO:0045597 211 0.033
single organism membrane fusion GO:0044801 37 0.032
negative regulation of membrane tubulation GO:1903526 2 0.032
regulation of cell migration GO:0030334 289 0.032
positive regulation of protein tyrosine kinase activity GO:0061098 24 0.032
Human
regulation of endopeptidase activity GO:0052548 170 0.032
glycolipid metabolic process GO:0006664 27 0.032
nuclear transport GO:0051169 179 0.032
hemopoiesis GO:0030097 180 0.032
regulation of alcohol biosynthetic process GO:1902930 22 0.032
positive regulation of stress activated mapk cascade GO:0032874 60 0.032
regulation of cell cycle GO:0051726 393 0.031
Human
cell cell signaling GO:0007267 155 0.031
calcium mediated signaling GO:0019722 44 0.031
regulation of map kinase activity GO:0043405 108 0.031
dendrite development GO:0016358 24 0.031
organophosphate catabolic process GO:0046434 430 0.031
regulation of membrane tubulation GO:1903525 2 0.031
negative regulation of wnt signaling pathway GO:0030178 69 0.031
immune response regulating signaling pathway GO:0002764 97 0.031
lipid modification GO:0030258 84 0.031
stem cell development GO:0048864 69 0.031
Mouse
negative regulation of transferase activity GO:0051348 124 0.031
positive regulation of b cell proliferation GO:0030890 12 0.030
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.030
positive regulation of cell migration GO:0030335 172 0.030
Human
regulation of synaptic transmission GO:0050804 11 0.030
lipid localization GO:0010876 106 0.030
lipid catabolic process GO:0016042 84 0.030
synaptic transmission GO:0007268 61 0.030
regulation of protein complex assembly GO:0043254 147 0.030
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.029
organelle fusion GO:0048284 36 0.029
late endosome to vacuole transport GO:0045324 2 0.029
osteoblast differentiation GO:0001649 92 0.029
phosphatidylinositol mediated signaling GO:0048015 55 0.029
regulation of sequestering of calcium ion GO:0051282 41 0.029
cell junction assembly GO:0034329 67 0.029
jak stat cascade GO:0007259 46 0.029
response to camp GO:0051591 25 0.029
cytosolic calcium ion homeostasis GO:0051480 89 0.029
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.028
transferrin transport GO:0033572 4 0.028
positive regulation of immune system process GO:0002684 283 0.028
Human

ADAM15 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.308
muscular disease DOID:0080000 114 0.188
musculoskeletal system disease DOID:17 223 0.188
joubert syndrome DOID:0050777 18 0.064
disease of cellular proliferation DOID:14566 174 0.063
muscle tissue disease DOID:66 113 0.061
central nervous system disease DOID:331 186 0.053
nervous system disease DOID:863 431 0.053
acquired metabolic disease DOID:0060158 58 0.050
myopathy DOID:423 104 0.047
inherited metabolic disorder DOID:655 242 0.043
retinal disease DOID:5679 118 0.035
sensory system disease DOID:0050155 203 0.035
eye and adnexa disease DOID:1492 150 0.035
eye disease DOID:5614 149 0.035
immune system disease DOID:2914 155 0.033