Homo sapiens

244 known processes

ADAM17

ADAM metallopeptidase domain 17

(Aliases: ADAM18,CSVP,CD156B,MGC71942,TACE)

ADAM17 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
hard palate development GO:0060022 1 0.989
cell fate commitment involved in pattern specification GO:0060581 1 0.799
positive regulation of phosphorylation GO:0042327 394 0.643
mating GO:0007618 1 0.592
taxis GO:0042330 157 0.588
positive regulation of protein phosphorylation GO:0001934 313 0.572
kidney morphogenesis GO:0060993 19 0.523
cell cell recognition GO:0009988 4 0.514
immunological synapse formation GO:0001771 1 0.497
nephron epithelium morphogenesis GO:0072088 15 0.492
locomotory behavior GO:0007626 1 0.490
regulation of locomotion GO:0040012 329 0.484
cell adhesion GO:0007155 325 0.472
biological adhesion GO:0022610 331 0.455
tripartite regional subdivision GO:0007351 2 0.425
segmentation GO:0035282 4 0.425
anterior posterior axis specification embryo GO:0008595 2 0.410
potassium ion transport GO:0006813 62 0.405
post embryonic development GO:0009791 2 0.397
circadian behavior GO:0048512 2 0.389
positive regulation of potassium ion transport GO:0043268 15 0.379
positive regulation of cellular component organization GO:0051130 376 0.373
Human
anterior posterior axis specification GO:0009948 2 0.372
branching morphogenesis of an epithelial tube GO:0048754 19 0.372
nephron epithelium development GO:0072009 23 0.372
cell junction assembly GO:0034329 67 0.371
cation transport GO:0006812 331 0.360
blastoderm segmentation GO:0007350 2 0.354
single organism cell adhesion GO:0098602 179 0.344
Human
metal ion transport GO:0030001 272 0.340
establishment of organelle localization GO:0051656 59 0.329
phasic smooth muscle contraction GO:0014821 6 0.329
neuronal action potential GO:0019228 9 0.319
oogenesis GO:0048477 2 0.302
rhythmic behavior GO:0007622 2 0.300
neuromuscular junction development GO:0007528 3 0.297
negative regulation of cell proliferation GO:0008285 228 0.288
regulation of myelination GO:0031641 1 0.277
response to abiotic stimulus GO:0009628 336 0.276
action potential GO:0001508 34 0.267
monovalent inorganic cation transport GO:0015672 128 0.260
regulation of kinase activity GO:0043549 314 0.257
oocyte differentiation GO:0009994 2 0.250
transmembrane transport GO:0055085 399 0.249
cellular protein complex assembly GO:0043623 188 0.248
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.240
regulation of actin polymerization or depolymerization GO:0008064 56 0.238
epithelium development GO:0060429 227 0.238
negative regulation of cell cycle GO:0045786 193 0.234
actin cytoskeleton organization GO:0030036 207 0.233
lymphocyte mediated immunity GO:0002449 48 0.229
ion transmembrane transport GO:0034220 338 0.228
actin filament based process GO:0030029 224 0.226
muscle contraction GO:0006936 73 0.220
renal system development GO:0072001 63 0.217
positive regulation of developmental process GO:0051094 314 0.213
Human
muscle system process GO:0003012 81 0.210
actin filament organization GO:0007015 128 0.209
female gamete generation GO:0007292 2 0.207
cytokine production GO:0001816 247 0.206
positive regulation of cell proliferation GO:0008284 301 0.204
regulation of cell cycle GO:0051726 393 0.203
cellular component morphogenesis GO:0032989 314 0.201
positive regulation of protein polymerization GO:0032273 45 0.198
system process GO:0003008 349 0.186
renal tubule development GO:0061326 19 0.184
membrane raft organization GO:0031579 10 0.184
nephron tubule morphogenesis GO:0072078 13 0.182
regulation of cellular ketone metabolic process GO:0010565 50 0.182
renal tubule morphogenesis GO:0061333 14 0.181
signal transduction by phosphorylation GO:0023014 297 0.178
Human
kidney epithelium development GO:0072073 25 0.178
immune response GO:0006955 307 0.177
Human Mouse
tube development GO:0035295 125 0.176
cellular amino acid metabolic process GO:0006520 116 0.175
regulation of mitotic cell cycle GO:0007346 189 0.169
single organismal cell cell adhesion GO:0016337 148 0.169
Human
positive regulation of organelle organization GO:0010638 195 0.167
growth GO:0040007 202 0.166
cell activation GO:0001775 213 0.165
Human Mouse
ribonucleoside catabolic process GO:0042454 406 0.165
positive regulation of transferase activity GO:0051347 227 0.165
regulation of transferase activity GO:0051338 355 0.164
nephron morphogenesis GO:0072028 15 0.162
regulation of protein localization to plasma membrane GO:1903076 40 0.162
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.162
regulation of actin filament based process GO:0032970 141 0.160
enzyme linked receptor protein signaling pathway GO:0007167 303 0.155
positive regulation of ion transport GO:0043270 87 0.149
ureteric bud morphogenesis GO:0060675 10 0.148
positive regulation of protein kinase activity GO:0045860 190 0.147
regulation of metal ion transport GO:0010959 120 0.147
transmission of nerve impulse GO:0019226 11 0.145
positive regulation of kinase activity GO:0033674 204 0.144
tissue morphogenesis GO:0048729 96 0.143
branching involved in ureteric bud morphogenesis GO:0001658 9 0.143
establishment of protein localization to membrane GO:0090150 121 0.142
nervous system development GO:0007399 293 0.142
endomembrane system organization GO:0010256 196 0.142
adherens junction assembly GO:0034333 34 0.141
ras protein signal transduction GO:0007265 73 0.141
tube morphogenesis GO:0035239 95 0.139
inorganic ion transmembrane transport GO:0098660 231 0.139
endothelial cell proliferation GO:0001935 65 0.138
neuron projection development GO:0031175 106 0.137
positive regulation of protein complex assembly GO:0031334 86 0.136
regulation of potassium ion transport GO:0043266 24 0.135
regulation of membrane potential GO:0042391 95 0.133
regulation of cell migration GO:0030334 289 0.130
divalent inorganic cation transport GO:0072511 158 0.130
positive regulation of actin filament polymerization GO:0030838 38 0.130
generation of neurons GO:0048699 152 0.129
smooth muscle contraction GO:0006939 14 0.128
regulation of chemotaxis GO:0050920 74 0.125
protein localization to synapse GO:0035418 2 0.122
dephosphorylation GO:0016311 209 0.122
activation of protein kinase activity GO:0032147 90 0.120
Human
neurological system process GO:0050877 163 0.120
cellular amine metabolic process GO:0044106 41 0.117
leukocyte activation GO:0045321 164 0.116
Human Mouse
regulation of actin filament polymerization GO:0030833 50 0.116
regulation of epithelial cell proliferation GO:0050678 113 0.115
regulation of ion transport GO:0043269 189 0.114
regulation of cellular amine metabolic process GO:0033238 11 0.114
regulation of cellular component biogenesis GO:0044087 281 0.112
epithelial cell proliferation GO:0050673 128 0.112
oocyte development GO:0048599 1 0.112
immune effector process GO:0002252 159 0.112
cell development GO:0048468 328 0.111
regulation of mononuclear cell proliferation GO:0032944 65 0.111
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.110
cardiac right ventricle morphogenesis GO:0003215 3 0.108
positive regulation of cytoskeleton organization GO:0051495 83 0.105
t cell cytokine production GO:0002369 12 0.105
negative regulation of apoptotic process GO:0043066 316 0.105
Rat
regulation of protein processing GO:0070613 150 0.104
regulation of meiotic cell cycle GO:0051445 4 0.103
protein modification by small protein conjugation GO:0032446 342 0.102
regulation of anatomical structure morphogenesis GO:0022603 286 0.101
Human
smooth muscle tissue development GO:0048745 3 0.101
regulation of nuclear division GO:0051783 65 0.100
negative regulation of cellular protein metabolic process GO:0032269 353 0.099
actin filament polymerization GO:0030041 45 0.096
nephron development GO:0072006 30 0.096
multicellular organismal signaling GO:0035637 34 0.096
adaptive immune response GO:0002250 49 0.095
Mouse
cytoplasmic transport GO:0016482 379 0.094
ureteric bud development GO:0001657 13 0.094
negative regulation of mitotic cell cycle GO:0045930 102 0.093
cell chemotaxis GO:0060326 112 0.092
regulation of proteolysis GO:0030162 293 0.092
mesonephric tubule development GO:0072164 14 0.092
small gtpase mediated signal transduction GO:0007264 78 0.092
negative regulation of catabolic process GO:0009895 104 0.092
lymphocyte activation GO:0046649 133 0.091
Mouse
regulation of cell morphogenesis GO:0022604 153 0.091
regulation of cytoskeleton organization GO:0051493 177 0.091
regulation of protein kinase b signaling GO:0051896 61 0.090
single organism cellular localization GO:1902580 332 0.090
cell junction organization GO:0034330 79 0.090
regulation of protein localization GO:0032880 296 0.090
Human
nucleotide catabolic process GO:0009166 408 0.089
regulation of cell adhesion GO:0030155 166 0.089
Human
protein catabolic process GO:0030163 325 0.089
vesicle mediated transport GO:0016192 371 0.089
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.088
regulation of cell division GO:0051302 116 0.087
regulation of lymphocyte proliferation GO:0050670 64 0.086
cellular cation homeostasis GO:0030003 163 0.085
regulation of actin cytoskeleton organization GO:0032956 116 0.085
negative regulation of hydrolase activity GO:0051346 182 0.084
positive regulation of cellular amine metabolic process GO:0033240 7 0.084
mitotic cell cycle GO:0000278 326 0.084
regulation of protein complex assembly GO:0043254 147 0.083
plasma membrane organization GO:0007009 115 0.082
palate development GO:0060021 13 0.082
regulation of protein polymerization GO:0032271 63 0.081
regulation of cellular component movement GO:0051270 334 0.081
epithelial tube morphogenesis GO:0060562 38 0.081
adherens junction organization GO:0034332 36 0.080
cellular homeostasis GO:0019725 196 0.080
regeneration GO:0031099 4 0.080
regulation of cellular amino acid metabolic process GO:0006521 6 0.080
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.080
mesonephric epithelium development GO:0072163 14 0.079
cellular ketone metabolic process GO:0042180 80 0.079
negative regulation of phosphatase activity GO:0010923 61 0.079
actin polymerization or depolymerization GO:0008154 56 0.079
protein localization to membrane GO:0072657 160 0.077
negative regulation of immune system process GO:0002683 136 0.077
purine nucleoside triphosphate catabolic process GO:0009146 392 0.077
positive regulation of cell death GO:0010942 263 0.076
cell cell signaling GO:0007267 155 0.076
jak stat cascade GO:0007259 46 0.076
regulation of cell motility GO:2000145 299 0.076
urogenital system development GO:0001655 65 0.076
skeletal system development GO:0001501 79 0.075
protein kinase b signaling GO:0043491 69 0.074
cellular macromolecular complex assembly GO:0034622 324 0.074
morphogenesis of a branching structure GO:0001763 21 0.074
nephron tubule development GO:0072080 17 0.073
mesonephros development GO:0001823 17 0.073
nucleoside catabolic process GO:0009164 408 0.073
negative regulation of epithelial cell proliferation GO:0050680 48 0.072
cell growth GO:0016049 160 0.072
peptidyl serine phosphorylation GO:0018105 101 0.072
amyloid precursor protein metabolic process GO:0042982 17 0.070
ribonucleotide catabolic process GO:0009261 405 0.070
negative regulation of catalytic activity GO:0043086 335 0.070
regulation of protein kinase activity GO:0045859 289 0.069
negative regulation of t cell proliferation GO:0042130 8 0.069
ion homeostasis GO:0050801 230 0.068
response to oxygen containing compound GO:1901700 369 0.068
calcium ion transmembrane transport GO:0070588 76 0.068
positive regulation of transport GO:0051050 336 0.067
Human
morphogenesis of an epithelium GO:0002009 60 0.067
positive regulation of programmed cell death GO:0043068 249 0.066
protein ubiquitination GO:0016567 314 0.065
negative regulation of phosphate metabolic process GO:0045936 267 0.065
nucleoside phosphate catabolic process GO:1901292 412 0.065
pattern specification process GO:0007389 43 0.064
purine nucleoside catabolic process GO:0006152 398 0.064
cytokine production involved in immune response GO:0002367 27 0.064
single organism membrane organization GO:0044802 268 0.064
multicellular organismal aging GO:0010259 3 0.064
t cell activation GO:0042110 99 0.064
Mouse
mononuclear cell proliferation GO:0032943 71 0.063
negative regulation of multicellular organismal process GO:0051241 317 0.063
negative regulation of dephosphorylation GO:0035305 63 0.063
protein maturation GO:0051604 233 0.062
modification dependent macromolecule catabolic process GO:0043632 212 0.061
neuron differentiation GO:0030182 138 0.061
proteasomal protein catabolic process GO:0010498 176 0.060
regulation of establishment of protein localization to plasma membrane GO:0090003 30 0.060
protein localization to plasma membrane GO:0072659 93 0.060
chemotaxis GO:0006935 157 0.057
cation transmembrane transport GO:0098655 238 0.057
skeletal system morphogenesis GO:0048705 24 0.056
regulation of dephosphorylation GO:0035303 96 0.056
amine metabolic process GO:0009308 44 0.055
regulation of leukocyte proliferation GO:0070663 67 0.055
regulation of cell activation GO:0050865 125 0.055
regulation of proteasomal protein catabolic process GO:0061136 87 0.054
synaptic transmission GO:0007268 61 0.054
response to radiation GO:0009314 151 0.053
notch signaling pathway GO:0007219 31 0.053
response to growth factor GO:0070848 205 0.052
cellular response to growth factor stimulus GO:0071363 197 0.052
cellular ion homeostasis GO:0006873 168 0.052
cellular calcium ion homeostasis GO:0006874 117 0.052
positive regulation of cell motility GO:2000147 177 0.052
regulation of protein maturation GO:1903317 150 0.052
negative regulation of protein metabolic process GO:0051248 391 0.052
regulation of axon guidance GO:1902667 3 0.051
positive regulation of nervous system development GO:0051962 54 0.051
reproductive process GO:0022414 106 0.051
lymphocyte proliferation GO:0046651 70 0.050
regulation of nervous system development GO:0051960 88 0.050
neuron development GO:0048666 113 0.050
cellular chemical homeostasis GO:0055082 180 0.050
negative regulation of protein kinase b signaling GO:0051898 17 0.049
negative regulation of cell activation GO:0050866 33 0.049
purine ribonucleoside metabolic process GO:0046128 437 0.049
leukocyte proliferation GO:0070661 74 0.048
embryonic skeletal system development GO:0048706 13 0.048
neurogenesis GO:0022008 169 0.048
cell morphogenesis GO:0000902 296 0.047
cellular divalent inorganic cation homeostasis GO:0072503 128 0.046
regulation of meiosis GO:0040020 3 0.046
regulation of protein serine threonine kinase activity GO:0071900 179 0.046
regulation of nucleotide catabolic process GO:0030811 205 0.046
leukocyte mediated immunity GO:0002443 59 0.045
gtp metabolic process GO:0046039 239 0.045
positive regulation of cellular component movement GO:0051272 181 0.045
positive regulation of locomotion GO:0040017 186 0.045
regulation of chromosome segregation GO:0051983 44 0.045
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.045
determination of adult lifespan GO:0008340 2 0.045
negative regulation of leukocyte activation GO:0002695 26 0.045
regulation of ion transmembrane transport GO:0034765 132 0.044
cell morphogenesis involved in differentiation GO:0000904 144 0.044
embryonic morphogenesis GO:0048598 85 0.044
positive regulation of cellular component biogenesis GO:0044089 158 0.044
calcium ion homeostasis GO:0055074 122 0.044
positive regulation of growth GO:0045927 58 0.044
negative regulation of protein maturation GO:1903318 142 0.044
cell projection organization GO:0030030 252 0.043
cell cell junction assembly GO:0007043 25 0.043
regulation of neuron differentiation GO:0045664 70 0.043
defense response GO:0006952 315 0.043
Human
regulation of ras protein signal transduction GO:0046578 155 0.043
establishment of mitotic spindle orientation GO:0000132 7 0.042
organ morphogenesis GO:0009887 147 0.042
inorganic cation transmembrane transport GO:0098662 194 0.042
regulation of chromosome organization GO:0033044 103 0.042
cellular modified amino acid metabolic process GO:0006575 64 0.042
purine ribonucleotide catabolic process GO:0009154 404 0.042
mitotic cell cycle process GO:1903047 286 0.042
regulation of cellular protein catabolic process GO:1903362 96 0.042
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.041
response to cytokine GO:0034097 232 0.041
Human
regulation of jak stat cascade GO:0046425 44 0.041
purine ribonucleoside catabolic process GO:0046130 398 0.041
chemical homeostasis GO:0048878 306 0.041
regulation of nucleotide metabolic process GO:0006140 269 0.041
membrane organization GO:0061024 292 0.041
regulation of purine nucleotide metabolic process GO:1900542 264 0.040
regulation of response to external stimulus GO:0032101 222 0.040
negative regulation of mitotic anaphase promoting complex activity GO:0060564 4 0.040
reactive nitrogen species metabolic process GO:2001057 3 0.040
behavior GO:0007610 112 0.040
regulation of cardiac muscle hypertrophy in response to stress GO:1903242 2 0.040
regulation of leukocyte activation GO:0002694 115 0.040
regulation of cell cycle process GO:0010564 266 0.039
carbohydrate derivative biosynthetic process GO:1901137 207 0.039
purine nucleotide catabolic process GO:0006195 405 0.039
chromosome segregation GO:0007059 114 0.039
salivary gland morphogenesis GO:0007435 4 0.038
regulation of cell cycle phase transition GO:1901987 126 0.038
microtubule based process GO:0007017 210 0.038
divalent metal ion transport GO:0070838 152 0.038
ribonucleoside triphosphate metabolic process GO:0009199 412 0.038
peripheral nervous system development GO:0007422 2 0.038
cell division GO:0051301 168 0.038
regulation of anatomical structure size GO:0090066 101 0.038
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.037
Mouse
small molecule biosynthetic process GO:0044283 157 0.037
sodium ion transport GO:0006814 61 0.037
cellular response to abiotic stimulus GO:0071214 117 0.037
regulation of cellular response to stress GO:0080135 244 0.037
regulation of cellular component size GO:0032535 82 0.037
canonical wnt signaling pathway GO:0060070 116 0.037
negative regulation of cell death GO:0060548 345 0.037
Rat
regulation of t cell activation GO:0050863 77 0.036
negative regulation of t cell activation GO:0050868 18 0.036
regulation of nucleoside metabolic process GO:0009118 209 0.035
peptidyl serine modification GO:0018209 106 0.035
t cell mediated immunity GO:0002456 25 0.035
metal ion homeostasis GO:0055065 169 0.034
regulation of phosphatase activity GO:0010921 81 0.034
anatomical structure formation involved in morphogenesis GO:0048646 284 0.034
Human
negative regulation of organelle organization GO:0010639 126 0.034
synaptic vesicle endocytosis GO:0048488 2 0.034
positive regulation of nucleoside metabolic process GO:0045979 186 0.033
positive regulation of protein localization to plasma membrane GO:1903078 20 0.033
glycosyl compound catabolic process GO:1901658 413 0.033
regulation of transmembrane transport GO:0034762 139 0.033
nucleoside triphosphate metabolic process GO:0009141 422 0.033
positive regulation of immune system process GO:0002684 283 0.032
regulation of growth GO:0040008 165 0.032
intracellular protein transport GO:0006886 270 0.032
protein processing GO:0016485 226 0.032
motor neuron axon guidance GO:0008045 2 0.031
regulation of lymphocyte activation GO:0051249 103 0.031
apoptotic signaling pathway GO:0097190 268 0.031
regulation of purine nucleotide catabolic process GO:0033121 205 0.031
ribonucleoside triphosphate catabolic process GO:0009203 391 0.031
establishment or maintenance of cell polarity GO:0007163 31 0.031
negative regulation of protein catabolic process GO:0042177 59 0.031
cell cycle checkpoint GO:0000075 117 0.031
digestive system development GO:0055123 75 0.031
regulation of cell development GO:0060284 161 0.031
regulation of t cell proliferation GO:0042129 42 0.031
response to organic cyclic compound GO:0014070 204 0.030
spinal cord dorsal ventral patterning GO:0021513 2 0.030
regulation of mapk cascade GO:0043408 262 0.030
Human
cellular response to oxygen containing compound GO:1901701 276 0.030
Human
negative regulation of proteolysis GO:0045861 132 0.030
circulatory system development GO:0072359 262 0.030
negative regulation of cell differentiation GO:0045596 171 0.030
cell projection morphogenesis GO:0048858 129 0.030
positive regulation of ras gtpase activity GO:0032320 117 0.029
ribonucleoside monophosphate metabolic process GO:0009161 187 0.029
small molecule catabolic process GO:0044282 92 0.029
guanosine containing compound catabolic process GO:1901069 239 0.029
cortical cytoskeleton organization GO:0030865 9 0.029
ribonucleoside monophosphate catabolic process GO:0009158 158 0.028
regulation of cytokine production GO:0001817 232 0.028
cell matrix adhesion GO:0007160 85 0.028
Human
cellular response to nitrogen compound GO:1901699 144 0.028
cellular protein catabolic process GO:0044257 261 0.028
spinal cord development GO:0021510 4 0.028
nucleoside monophosphate catabolic process GO:0009125 159 0.028
chordate embryonic development GO:0043009 34 0.028
negative regulation of mononuclear cell proliferation GO:0032945 15 0.028
response to biotic stimulus GO:0009607 276 0.028
negative regulation of lymphocyte activation GO:0051250 24 0.028
purine nucleoside monophosphate metabolic process GO:0009126 186 0.028
negative regulation of developmental process GO:0051093 247 0.028
regulation of behavior GO:0050795 82 0.027
purine containing compound catabolic process GO:0072523 411 0.027
negative regulation of leukocyte proliferation GO:0070664 16 0.027
peptidyl tyrosine modification GO:0018212 170 0.027
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.027
regulation of notch signaling pathway GO:0008593 18 0.027
positive regulation of apoptotic process GO:0043065 246 0.027
positive regulation of cell cycle process GO:0090068 106 0.027
tight junction assembly GO:0070830 14 0.027
cell cycle phase transition GO:0044770 173 0.026
positive regulation of cell migration GO:0030335 172 0.026
embryonic skeletal system morphogenesis GO:0048704 9 0.026
positive regulation of gtp catabolic process GO:0033126 166 0.026
post embryonic organ development GO:0048569 1 0.026
establishment of spindle orientation GO:0051294 9 0.026
positive regulation of nucleotide metabolic process GO:0045981 230 0.026
negative regulation of programmed cell death GO:0043069 321 0.026
Rat
cellular response to dna damage stimulus GO:0006974 379 0.026
regulation of cell differentiation GO:0045595 393 0.026
positive regulation of gtpase activity GO:0043547 166 0.025
regulation of cell projection organization GO:0031344 107 0.025
positive regulation of hydrolase activity GO:0051345 331 0.025
negative regulation of chromosome organization GO:2001251 48 0.025
organic acid biosynthetic process GO:0016053 97 0.025
positive regulation of cellular catabolic process GO:0031331 284 0.025
eye development GO:0001654 42 0.025
positive regulation of cell differentiation GO:0045597 211 0.025
divalent inorganic cation homeostasis GO:0072507 136 0.025
positive regulation of establishment of protein localization to plasma membrane GO:0090004 18 0.025
negative regulation of cytosolic calcium ion concentration GO:0051481 1 0.025
positive regulation of nucleotide catabolic process GO:0030813 185 0.024
cellular lipid metabolic process GO:0044255 303 0.024
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.024
regulation of gtpase activity GO:0043087 180 0.024
embryonic organ morphogenesis GO:0048562 24 0.024
dna repair GO:0006281 198 0.024
purine nucleoside monophosphate catabolic process GO:0009128 158 0.024
organophosphate catabolic process GO:0046434 430 0.024
nucleoside triphosphate catabolic process GO:0009143 394 0.024
response to oxygen levels GO:0070482 100 0.024
wound healing GO:0042060 115 0.024
positive regulation of endocytosis GO:0045807 42 0.024
regulation of neurogenesis GO:0050767 82 0.024
negative regulation of intracellular signal transduction GO:1902532 183 0.024
inner ear morphogenesis GO:0042472 4 0.023
response to oxidative stress GO:0006979 121 0.023
Human
response to inorganic substance GO:0010035 127 0.023
Human
response to nitrogen compound GO:1901698 184 0.023
regionalization GO:0003002 29 0.023
regulation of synaptic plasticity GO:0048167 3 0.023
regulation of muscle system process GO:0090257 53 0.023
embryonic organ development GO:0048568 36 0.023
peptidyl tyrosine dephosphorylation GO:0035335 36 0.023
response to hormone GO:0009725 175 0.023
cation homeostasis GO:0055080 189 0.023
production of molecular mediator of immune response GO:0002440 37 0.022
positive regulation of camp dependent protein kinase activity GO:2000481 4 0.022
response to lipid GO:0033993 206 0.022
developmental maturation GO:0021700 28 0.022
sequestering of metal ion GO:0051238 24 0.022
secretion GO:0046903 254 0.022
Human
lipid biosynthetic process GO:0008610 177 0.022
cellular metal ion homeostasis GO:0006875 146 0.021
embryo development GO:0009790 123 0.021
photoreceptor cell differentiation GO:0046530 2 0.021
associative learning GO:0008306 1 0.021
histone modification GO:0016570 251 0.021
carboxylic acid biosynthetic process GO:0046394 97 0.021
sensory perception of smell GO:0007608 2 0.021
response to light stimulus GO:0009416 87 0.021
cardiac muscle adaptation GO:0014887 4 0.021
peptidyl tyrosine phosphorylation GO:0018108 170 0.021
positive regulation of cytokine production GO:0001819 167 0.021
cortical actin cytoskeleton organization GO:0030866 9 0.021
atp catabolic process GO:0006200 157 0.021
erk1 and erk2 cascade GO:0070371 104 0.021
epithelial cell differentiation GO:0030855 141 0.021
Human
regulation of leukocyte chemotaxis GO:0002688 46 0.020
sister chromatid cohesion GO:0007062 24 0.020
negative regulation of apoptotic signaling pathway GO:2001234 97 0.020
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.020
cellular response to radiation GO:0071478 65 0.020
establishment of cell polarity GO:0030010 22 0.020
protein autophosphorylation GO:0046777 123 0.020
spermatid differentiation GO:0048515 4 0.020
negative regulation of cellular protein catabolic process GO:1903363 38 0.020
gtp catabolic process GO:0006184 237 0.020
arginine metabolic process GO:0006525 3 0.020
negative regulation of cell cycle phase transition GO:1901988 89 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.020
regulation of peptidyl serine phosphorylation GO:0033135 50 0.020
positive regulation of chemotaxis GO:0050921 57 0.020
reproductive structure development GO:0048608 55 0.020
developmental process involved in reproduction GO:0003006 66 0.020
limbic system development GO:0021761 3 0.020
leukocyte chemotaxis GO:0030595 76 0.020

ADAM17 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.168
disease of cellular proliferation DOID:14566 174 0.168
organ system cancer DOID:0050686 164 0.168
disease of metabolism DOID:0014667 295 0.061
inherited metabolic disorder DOID:655 242 0.061
disease of mental health DOID:150 70 0.030
sensory system disease DOID:0050155 203 0.021
Human
nervous system disease DOID:863 431 0.021
Human
central nervous system disease DOID:331 186 0.021
cardiovascular system disease DOID:1287 106 0.021
gastrointestinal system disease DOID:77 36 0.020