Homo sapiens

0 known processes

ADAMTS2

ADAM metallopeptidase with thrombospondin type 1 motif, 2

(Aliases: PNPI,NPI,ADAMTS-3,ADAMTS-2,PCI-NP,ADAM-TS2,PCPNI,PC I-NP,PCINP,DKFZp686F12218)

ADAMTS2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
biological adhesion GO:0022610 331 0.695
Human
regulation of cell migration GO:0030334 289 0.643
regulation of locomotion GO:0040012 329 0.547
multicellular organismal metabolic process GO:0044236 34 0.503
Human
cell aggregation GO:0098743 1 0.456
embryonic morphogenesis GO:0048598 85 0.415
positive regulation of locomotion GO:0040017 186 0.396
response to growth factor GO:0070848 205 0.389
Human
regulation of cell motility GO:2000145 299 0.383
regulation of cell differentiation GO:0045595 393 0.363
Human
negative regulation of multicellular organismal process GO:0051241 317 0.359
Human
anatomical structure formation involved in morphogenesis GO:0048646 284 0.341
cell adhesion GO:0007155 325 0.339
Human
cellular response to growth factor stimulus GO:0071363 197 0.330
Human
enzyme linked receptor protein signaling pathway GO:0007167 303 0.324
Human
blood vessel morphogenesis GO:0048514 162 0.323
positive regulation of cellular component movement GO:0051272 181 0.321
regulation of cellular component movement GO:0051270 334 0.319
regulation of cell adhesion GO:0030155 166 0.315
Human
tube development GO:0035295 125 0.310
Human Mouse
soft palate development GO:0060023 3 0.285
positive regulation of cell migration GO:0030335 172 0.285
vasculature development GO:0001944 181 0.280
positive regulation of odontogenesis GO:0042482 3 0.274
organ morphogenesis GO:0009887 147 0.241
ossification GO:0001503 121 0.239
blood vessel development GO:0001568 172 0.225
cellular response to endogenous stimulus GO:0071495 336 0.221
Human
small gtpase mediated signal transduction GO:0007264 78 0.213
mesenchyme development GO:0060485 59 0.207
regulation of anatomical structure morphogenesis GO:0022603 286 0.207
Human
positive regulation of cell motility GO:2000147 177 0.205
positive regulation of mapk cascade GO:0043410 190 0.200
circulatory system development GO:0072359 262 0.200
cell substrate adhesion GO:0031589 132 0.184
Human
response to oxygen containing compound GO:1901700 369 0.182
negative regulation of cell differentiation GO:0045596 171 0.182
Human
endodermal cell differentiation GO:0035987 31 0.177
cell matrix adhesion GO:0007160 85 0.176
Human
mesenchymal cell development GO:0014031 50 0.172
cell morphogenesis GO:0000902 296 0.172
tube morphogenesis GO:0035239 95 0.171
Human
cell development GO:0048468 328 0.171
positive regulation of transport GO:0051050 336 0.169
positive regulation of epithelial cell proliferation involved in wound healing GO:0060054 3 0.166
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation GO:0044338 2 0.163
positive regulation of cellular component organization GO:0051130 376 0.162
cellular component morphogenesis GO:0032989 314 0.154
negative regulation of cellular component movement GO:0051271 106 0.145
formation of primary germ layer GO:0001704 42 0.145
rho protein signal transduction GO:0007266 26 0.143
single organism cell adhesion GO:0098602 179 0.134
Human
epithelium development GO:0060429 227 0.132
Human
positive regulation of developmental process GO:0051094 314 0.130
cardiovascular system development GO:0072358 262 0.129
cell morphogenesis involved in differentiation GO:0000904 144 0.129
morphogenesis of a branching structure GO:0001763 21 0.128
digestive system development GO:0055123 75 0.126
regulation of cellular ketone metabolic process GO:0010565 50 0.125
ameboidal type cell migration GO:0001667 135 0.123
regulation of response to external stimulus GO:0032101 222 0.123
Human
system process GO:0003008 349 0.122
digestive tract development GO:0048565 75 0.121
single organismal cell cell adhesion GO:0016337 148 0.120
Human
tissue morphogenesis GO:0048729 96 0.118
Human
glycoprotein metabolic process GO:0009100 110 0.116
Human
epithelial tube morphogenesis GO:0060562 38 0.116
Human
negative regulation of developmental process GO:0051093 247 0.116
Human
wound healing GO:0042060 115 0.113
Human
membrane organization GO:0061024 292 0.111
mesenchymal cell differentiation GO:0048762 52 0.109
response to wounding GO:0009611 168 0.107
Human
positive regulation of cellular amine metabolic process GO:0033240 7 0.107
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.105
Human
skeletal system development GO:0001501 79 0.105
Human
digestive tract morphogenesis GO:0048546 56 0.100
positive regulation of aldosterone metabolic process GO:0032346 2 0.100
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.098
cartilage condensation GO:0001502 1 0.098
endoderm formation GO:0001706 33 0.098
regulation of odontogenesis GO:0042481 4 0.098
positive regulation of phosphorylation GO:0042327 394 0.097
paramesonephric duct development GO:0061205 2 0.096
endoderm development GO:0007492 33 0.094
gastrulation GO:0007369 51 0.092
negative regulation of cell motility GO:2000146 104 0.091
negative regulation of cell migration GO:0030336 102 0.089
connective tissue development GO:0061448 39 0.088
Human
positive regulation of hydrolase activity GO:0051345 331 0.087
response to cytokine GO:0034097 232 0.087
Human
negative regulation of gastrulation GO:2000542 4 0.086
negative regulation of cell adhesion GO:0007162 64 0.085
Human
positive regulation of cell differentiation GO:0045597 211 0.084
positive regulation of protein phosphorylation GO:0001934 313 0.084
extracellular matrix organization GO:0030198 41 0.083
Mouse
cellular ketone metabolic process GO:0042180 80 0.082
osteoblast differentiation GO:0001649 92 0.081
response to lipid GO:0033993 206 0.081
morphogenesis of an epithelium GO:0002009 60 0.080
Human
positive regulation of cell proliferation GO:0008284 301 0.079
purine ribonucleotide catabolic process GO:0009154 404 0.077
regulation of ossification GO:0030278 58 0.077
negative regulation of endodermal cell differentiation GO:1903225 2 0.077
skeletal system morphogenesis GO:0048705 24 0.076
regulation of cellular amine metabolic process GO:0033238 11 0.076
regulation of cellular amino acid metabolic process GO:0006521 6 0.076
proteoglycan metabolic process GO:0006029 29 0.076
Human
leukocyte migration GO:0050900 107 0.074
biomineral tissue development GO:0031214 39 0.074
cell activation GO:0001775 213 0.073
Human
chemotaxis GO:0006935 157 0.071
immune response GO:0006955 307 0.071
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.071
tissue migration GO:0090130 119 0.071
cellular amino acid metabolic process GO:0006520 116 0.070
negative regulation of immune system process GO:0002683 136 0.069
angiogenesis GO:0001525 147 0.069
negative regulation of embryonic development GO:0045992 4 0.069
hematopoietic or lymphoid organ development GO:0048534 186 0.068
cellular amine metabolic process GO:0044106 41 0.068
collagen metabolic process GO:0032963 28 0.067
Human
regulation of cellular response to growth factor stimulus GO:0090287 76 0.067
Human
epithelial cell migration GO:0010631 119 0.067
muscle structure development GO:0061061 98 0.067
negative regulation of locomotion GO:0040013 118 0.066
regulation of cellular component biogenesis GO:0044087 281 0.065
negative regulation of cellular component organization GO:0051129 235 0.064
glial cell migration GO:0008347 4 0.064
canonical wnt signaling pathway involved in osteoblast differentiation GO:0044339 2 0.064
regulation of epithelial to mesenchymal transition GO:0010717 37 0.064
regulation of nucleotide metabolic process GO:0006140 269 0.063
response to organic cyclic compound GO:0014070 204 0.062
stem cell development GO:0048864 69 0.062
negative regulation of programmed cell death GO:0043069 321 0.062
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.062
regulation of purine nucleotide metabolic process GO:1900542 264 0.061
ras protein signal transduction GO:0007265 73 0.061
regulation of immune response GO:0050776 201 0.060
positive regulation of aldosterone biosynthetic process GO:0032349 2 0.060
extracellular structure organization GO:0043062 41 0.059
Mouse
embryo development GO:0009790 123 0.059
multicellular organismal macromolecule metabolic process GO:0044259 29 0.059
Human
positive regulation of keratinocyte migration GO:0051549 4 0.058
regulation of peptidase activity GO:0052547 180 0.058
cellular response to oxygen containing compound GO:1901701 276 0.058
negative regulation of testicular blood vessel morphogenesis GO:0061369 1 0.057
sensory perception of light stimulus GO:0050953 35 0.056
peptidyl tyrosine modification GO:0018212 170 0.056
female gamete generation GO:0007292 2 0.056
taxis GO:0042330 157 0.056
negative regulation of cell death GO:0060548 345 0.056
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.055
response to external biotic stimulus GO:0043207 261 0.054
neurological system process GO:0050877 163 0.053
embryonic forelimb morphogenesis GO:0035115 4 0.053
forelimb morphogenesis GO:0035136 4 0.053
regulation of hormone levels GO:0010817 125 0.052
epithelial to mesenchymal transition GO:0001837 48 0.052
vesicle mediated transport GO:0016192 371 0.050
positive regulation of epithelial cell migration GO:0010634 55 0.050
cytokine production GO:0001816 247 0.049
Human
regulation of purine nucleotide catabolic process GO:0033121 205 0.049
organophosphate catabolic process GO:0046434 430 0.049
regulation of protein localization GO:0032880 296 0.048
protein oligomerization GO:0051259 173 0.047
defense response GO:0006952 315 0.047
Human
dermatome development GO:0061054 3 0.047
plasma membrane organization GO:0007009 115 0.047
protein maturation GO:0051604 233 0.047
Human Mouse
nucleotide catabolic process GO:0009166 408 0.047
skin development GO:0043588 76 0.047
Mouse
positive regulation of hormone biosynthetic process GO:0046886 4 0.047
regulation of cytokine production GO:0001817 232 0.046
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.046
response to biotic stimulus GO:0009607 276 0.045
cellular divalent inorganic cation homeostasis GO:0072503 128 0.044
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.044
oogenesis GO:0048477 2 0.044
positive regulation of chemotaxis GO:0050921 57 0.044
gtp catabolic process GO:0006184 237 0.044
regulation of cell cell adhesion GO:0022407 57 0.044
Human
positive regulation of gtp catabolic process GO:0033126 166 0.043
regulation of kinase activity GO:0043549 314 0.043
positive regulation of tooth mineralization GO:0070172 2 0.043
sprouting angiogenesis GO:0002040 29 0.043
protein processing GO:0016485 226 0.043
Human Mouse
negative regulation of apoptotic process GO:0043066 316 0.043
ribonucleotide catabolic process GO:0009261 405 0.043
response to hormone GO:0009725 175 0.042
response to abiotic stimulus GO:0009628 336 0.042
regulation of cell development GO:0060284 161 0.042
nucleoside phosphate catabolic process GO:1901292 412 0.042
bone development GO:0060348 26 0.042
positive regulation of immune system process GO:0002684 283 0.042
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.041
response to organonitrogen compound GO:0010243 156 0.041
positive regulation of nucleotide metabolic process GO:0045981 230 0.041
single organism membrane organization GO:0044802 268 0.041
cellular chemical homeostasis GO:0055082 180 0.041
blastoderm segmentation GO:0007350 2 0.041
negative regulation of platelet aggregation GO:0090331 3 0.040
Human
nervous system development GO:0007399 293 0.040
regulation of epithelial cell migration GO:0010632 93 0.039
positive regulation of transferase activity GO:0051347 227 0.039
response to other organism GO:0051707 261 0.039
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.039
positive regulation of kinase activity GO:0033674 204 0.039
regulation of bmp signaling pathway GO:0030510 27 0.039
nucleoside triphosphate catabolic process GO:0009143 394 0.039
post embryonic development GO:0009791 2 0.039
neurogenesis GO:0022008 169 0.039
positive regulation of nucleotide catabolic process GO:0030813 185 0.039
blood circulation GO:0008015 113 0.039
bone mineralization GO:0030282 34 0.039
amine metabolic process GO:0009308 44 0.038
positive regulation of programmed cell death GO:0043068 249 0.038
negative regulation of cell proliferation GO:0008285 228 0.038
positive regulation of epithelial cell proliferation GO:0050679 65 0.038
regulation of protein transport GO:0051223 213 0.038
purine nucleotide catabolic process GO:0006195 405 0.038
regulation of cell substrate adhesion GO:0010810 68 0.038
detection of mechanical stimulus involved in sensory perception GO:0050974 1 0.038
positive regulation of cytokine production GO:0001819 167 0.037
purine nucleoside triphosphate metabolic process GO:0009144 412 0.037
growth GO:0040007 202 0.037
positive regulation of organelle organization GO:0010638 195 0.037
mapk cascade GO:0000165 288 0.037
purine containing compound catabolic process GO:0072523 411 0.037
transmembrane transport GO:0055085 399 0.036
positive regulation of protein kinase activity GO:0045860 190 0.036
detection of stimulus GO:0051606 85 0.036
ribonucleoside catabolic process GO:0042454 406 0.036
stem cell differentiation GO:0048863 93 0.036
calcium ion homeostasis GO:0055074 122 0.036
non canonical wnt signaling pathway via mapk cascade GO:0038030 4 0.036
positive regulation of cell death GO:0010942 263 0.036
purine ribonucleoside metabolic process GO:0046128 437 0.036
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.035
regulation of protein kinase activity GO:0045859 289 0.035
regulation of keratinocyte migration GO:0051547 4 0.035
sensory perception GO:0007600 103 0.035
nucleoside catabolic process GO:0009164 408 0.035
positive regulation of cell adhesion GO:0045785 84 0.034
cell projection organization GO:0030030 252 0.034
regulation of stem cell differentiation GO:2000736 56 0.034
ribonucleoside triphosphate metabolic process GO:0009199 412 0.034
segmentation GO:0035282 4 0.034
endochondral bone morphogenesis GO:0060350 3 0.034
collagen fibril organization GO:0030199 10 0.034
Mouse
endomembrane system organization GO:0010256 196 0.034
cell cell signaling GO:0007267 155 0.033
cytosolic calcium ion homeostasis GO:0051480 89 0.033
blood coagulation GO:0007596 76 0.033
Human
cellular metal ion homeostasis GO:0006875 146 0.033
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.033
single organism cellular localization GO:1902580 332 0.033
immune system development GO:0002520 195 0.033
negative regulation of androgen biosynthetic process GO:2000180 1 0.033
regulation of endopeptidase activity GO:0052548 170 0.033
heart development GO:0007507 95 0.033
regulation of establishment of protein localization GO:0070201 242 0.033
regulation of ras protein signal transduction GO:0046578 155 0.033
regulation of cell growth GO:0001558 135 0.033
secretion GO:0046903 254 0.033
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.033
regulation of transferase activity GO:0051338 355 0.032
positive regulation of nucleoside metabolic process GO:0045979 186 0.032
multicellular organismal aging GO:0010259 3 0.032
gtp metabolic process GO:0046039 239 0.032
regulation of gtp catabolic process GO:0033124 180 0.032
regulation of proteolysis GO:0030162 293 0.032
cell chemotaxis GO:0060326 112 0.032
negative regulation of protein metabolic process GO:0051248 391 0.031
regulation of cytoskeleton organization GO:0051493 177 0.031
regulation of gtpase activity GO:0043087 180 0.031
replacement ossification GO:0036075 1 0.031
regulation of leukocyte migration GO:0002685 63 0.031
regulation of endodermal cell differentiation GO:1903224 3 0.030
visual perception GO:0007601 27 0.030
embryonic skeletal joint development GO:0072498 2 0.030
small molecule biosynthetic process GO:0044283 157 0.030
detection of mechanical stimulus GO:0050982 4 0.030
purine nucleoside catabolic process GO:0006152 398 0.030
eye development GO:0001654 42 0.030
Human
anterior posterior axis specification GO:0009948 2 0.030
regulation of small gtpase mediated signal transduction GO:0051056 156 0.030
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.030
Human
regulation of secretion GO:0051046 194 0.030
regulation of chemotaxis GO:0050920 74 0.029
lipid metabolic process GO:0006629 381 0.029
positive regulation of apoptotic process GO:0043065 246 0.029
response to steroid hormone GO:0048545 80 0.029
cytoplasmic transport GO:0016482 379 0.029
purine ribonucleoside catabolic process GO:0046130 398 0.029
forebrain regionalization GO:0021871 3 0.029
cartilage development GO:0051216 31 0.028
Human
regulation of cellular response to stress GO:0080135 244 0.028
secretion by cell GO:0032940 226 0.028
embryonic skeletal system development GO:0048706 13 0.028
guanosine containing compound catabolic process GO:1901069 239 0.028
negative regulation of testosterone biosynthetic process GO:2000225 1 0.028
positive regulation of cellular component biogenesis GO:0044089 158 0.028
cell type specific apoptotic process GO:0097285 125 0.028
protein localization to organelle GO:0033365 280 0.028
positive regulation of leukocyte chemotaxis GO:0002690 38 0.028
embryonic skeletal joint morphogenesis GO:0060272 2 0.028
retinal ganglion cell axon guidance GO:0031290 2 0.028
canonical wnt signaling pathway GO:0060070 116 0.028
glycosyl compound catabolic process GO:1901658 413 0.027
regulation of cartilage development GO:0061035 12 0.027
Human
regulation of vasculature development GO:1901342 97 0.027
negative regulation of hydrolase activity GO:0051346 182 0.027
ion transmembrane transport GO:0034220 338 0.027
positive regulation of response to external stimulus GO:0032103 88 0.027
guanosine containing compound metabolic process GO:1901068 244 0.026
negative regulation of catalytic activity GO:0043086 335 0.026
regulation of secretion by cell GO:1903530 177 0.026
regulation of response to wounding GO:1903034 101 0.026
Human
response to transforming growth factor beta GO:0071559 94 0.026
epithelium migration GO:0090132 119 0.026
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.026
canonical wnt signaling pathway involved in cardiac muscle cell fate commitment GO:0061317 3 0.026
response to nitrogen compound GO:1901698 184 0.026
head development GO:0060322 108 0.025
bone trabecula formation GO:0060346 1 0.025
negative regulation of glomerulus development GO:0090194 2 0.025
negative regulation of transport GO:0051051 176 0.025
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.025
negative regulation of peptidase activity GO:0010466 91 0.025
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.025
brain development GO:0007420 97 0.025
sensory perception of sound GO:0007605 37 0.024
regulation of testosterone biosynthetic process GO:2000224 2 0.024
cellular response to organic cyclic compound GO:0071407 127 0.024
regulation of ion transport GO:0043269 189 0.024
wnt signaling pathway GO:0016055 156 0.024
regulation of angiogenesis GO:0045765 92 0.024
chondrocyte development GO:0002063 1 0.024
intracellular protein transport GO:0006886 270 0.024
spinal cord development GO:0021510 4 0.024
cellular response to nitrogen compound GO:1901699 144 0.024
gland development GO:0048732 48 0.024
positive regulation of cellular catabolic process GO:0031331 284 0.024
hemopoiesis GO:0030097 180 0.024
cellular ion homeostasis GO:0006873 168 0.024
negative regulation of reactive oxygen species metabolic process GO:2000378 11 0.024
cation transport GO:0006812 331 0.024
regulation of actin cytoskeleton organization GO:0032956 116 0.024
positive regulation of steroid hormone biosynthetic process GO:0090031 2 0.023
stress fiber assembly GO:0043149 40 0.023
negative regulation of blood coagulation GO:0030195 22 0.023
Human
positive regulation of catabolic process GO:0009896 310 0.023
peptide cross linking GO:0018149 12 0.023
luteolysis GO:0001554 3 0.023
circulatory system process GO:0003013 113 0.023
positive regulation of intracellular transport GO:0032388 104 0.023
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.023
regulation of nucleoside metabolic process GO:0009118 209 0.023
generation of neurons GO:0048699 152 0.023
response to virus GO:0009615 126 0.023
protein localization to plasma membrane GO:0072659 93 0.023
purine nucleoside triphosphate catabolic process GO:0009146 392 0.023
response to radiation GO:0009314 151 0.023
neuromuscular junction development GO:0007528 3 0.023
protein localization to nucleus GO:0034504 136 0.023
divalent metal ion transport GO:0070838 152 0.022
positive regulation of cytoskeleton organization GO:0051495 83 0.022
cellular response to cytokine stimulus GO:0071345 181 0.022
Human
actin filament based process GO:0030029 224 0.022
endothelial cell proliferation GO:0001935 65 0.022
determination of adult lifespan GO:0008340 2 0.022
regulation of growth GO:0040008 165 0.022
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 1 0.022
reproductive process GO:0022414 106 0.022
Mouse
limb development GO:0060173 23 0.022
nucleoside triphosphate metabolic process GO:0009141 422 0.022
regulation of defense response GO:0031347 154 0.022
Human
negative regulation of kidney development GO:0090185 2 0.022
divalent inorganic cation transport GO:0072511 158 0.022
ion homeostasis GO:0050801 230 0.022
positive regulation of behavior GO:0048520 60 0.022
regulation of cysteine type endopeptidase activity GO:2000116 127 0.022
central nervous system development GO:0007417 123 0.022
mesonephric duct development GO:0072177 3 0.021
cell projection morphogenesis GO:0048858 129 0.021
positive regulation of wnt signaling pathway GO:0030177 54 0.021
metal ion homeostasis GO:0055065 169 0.021
regulation of cell morphogenesis GO:0022604 153 0.021
testosterone biosynthetic process GO:0061370 2 0.021
regulation of wound healing GO:0061041 56 0.021
Human
protein localization to membrane GO:0072657 160 0.021
cell growth GO:0016049 160 0.021
mitotic cell cycle process GO:1903047 286 0.021
neurotransmitter secretion GO:0007269 4 0.021
positive regulation of cortisol biosynthetic process GO:2000066 1 0.021
hormone metabolic process GO:0042445 61 0.021
positive regulation of peptidase activity GO:0010952 88 0.021
protein homooligomerization GO:0051260 100 0.021
negative regulation of cellular protein metabolic process GO:0032269 353 0.021
positive regulation of endothelial cell proliferation GO:0001938 37 0.021
regulation of blood pressure GO:0008217 30 0.021
peptidyl tyrosine phosphorylation GO:0018108 170 0.021
cellular response to dna damage stimulus GO:0006974 379 0.020
protein catabolic process GO:0030163 325 0.020
Human
inflammatory response GO:0006954 79 0.020
Human
ribonucleoside triphosphate catabolic process GO:0009203 391 0.020
regulation of nucleotide catabolic process GO:0030811 205 0.020
locomotory behavior GO:0007626 1 0.020
cellular cation homeostasis GO:0030003 163 0.020
carbohydrate derivative biosynthetic process GO:1901137 207 0.020
oocyte development GO:0048599 1 0.020
positive regulation of secretion GO:0051047 116 0.020
negative regulation of cell cycle GO:0045786 193 0.020
renal system development GO:0072001 63 0.020
regulation of cellular response to hepatocyte growth factor stimulus GO:2001112 1 0.020
Human
cellular macromolecule catabolic process GO:0044265 380 0.020
Human
oocyte differentiation GO:0009994 2 0.020
regulation of protein serine threonine kinase activity GO:0071900 179 0.020
anterior posterior axis specification embryo GO:0008595 2 0.020
organic hydroxy compound metabolic process GO:1901615 147 0.020
negative regulation of homotypic cell cell adhesion GO:0034111 3 0.020
Human
regulation of canonical wnt signaling pathway GO:0060828 88 0.019
regulation of intracellular transport GO:0032386 195 0.019
positive regulation of gtpase activity GO:0043547 166 0.019
dephosphorylation GO:0016311 209 0.019
positive regulation of immune response GO:0050778 159 0.019
positive regulation of proteolysis GO:0045862 142 0.019
regulation of ras gtpase activity GO:0032318 128 0.019
positive regulation of secretion by cell GO:1903532 108 0.019
embryonic hindlimb morphogenesis GO:0035116 2 0.019
tissue regeneration GO:0042246 3 0.019
ureteric bud development GO:0001657 13 0.019
metal ion transport GO:0030001 272 0.019
erk1 and erk2 cascade GO:0070371 104 0.019
regulation of multi organism process GO:0043900 157 0.019
regulation of cell matrix adhesion GO:0001952 42 0.019
regulation of cell activation GO:0050865 125 0.019
Human
cation homeostasis GO:0055080 189 0.019
urogenital system development GO:0001655 65 0.019
epiboly involved in wound healing GO:0090505 8 0.019
response to estrogen GO:0043627 47 0.019
regulation of platelet aggregation GO:0090330 4 0.018
Human
apoptotic signaling pathway GO:0097190 268 0.018
negative regulation of cell substrate adhesion GO:0010812 24 0.018
embryonic organ development GO:0048568 36 0.018
cellular response to lipid GO:0071396 127 0.018
regulation of vesicle mediated transport GO:0060627 130 0.018
cellular homeostasis GO:0019725 196 0.018
cellular protein catabolic process GO:0044257 261 0.018
Human
organ formation GO:0048645 3 0.018
palate development GO:0060021 13 0.018
zymogen activation GO:0031638 70 0.018
single organism reproductive process GO:0044702 98 0.018
Mouse
signal transduction by phosphorylation GO:0023014 297 0.018
patterning of blood vessels GO:0001569 2 0.018
positive regulation of stem cell differentiation GO:2000738 29 0.018
positive regulation of ossification GO:0045778 32 0.018
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.018
regulation of leukocyte chemotaxis GO:0002688 46 0.018
platelet activation GO:0030168 44 0.018
Human
sensory perception of mechanical stimulus GO:0050954 37 0.018
epithelial cell proliferation GO:0050673 128 0.018
detection of stimulus involved in sensory perception GO:0050906 43 0.018
positive regulation of angiogenesis GO:0045766 51 0.018
mitotic cell cycle GO:0000278 326 0.018
reactive oxygen species metabolic process GO:0072593 75 0.018
negative regulation of phosphate metabolic process GO:0045936 267 0.018
lipid transport GO:0006869 90 0.017
embryonic organ morphogenesis GO:0048562 24 0.017
anion transport GO:0006820 161 0.017
organelle assembly GO:0070925 176 0.017
morphogenesis of an epithelial sheet GO:0002011 12 0.017
developmental process involved in reproduction GO:0003006 66 0.017
regulation of mapk cascade GO:0043408 262 0.017
cellular response to vascular endothelial growth factor stimulus GO:0035924 26 0.017
Human
response to drug GO:0042493 81 0.017
positive regulation of protein transport GO:0051222 135 0.017
chondroitin sulfate metabolic process GO:0030204 7 0.017
negative regulation of epithelial cell migration GO:0010633 38 0.017
regulation of endothelial cell proliferation GO:0001936 56 0.017
positive regulation of ras gtpase activity GO:0032320 117 0.017
sulfur compound metabolic process GO:0006790 101 0.017
response to inorganic substance GO:0010035 127 0.017
leukocyte activation GO:0045321 164 0.017

ADAMTS2 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.169
connective tissue disease DOID:65 109 0.162
bone disease DOID:0080001 88 0.106
osteochondrodysplasia DOID:2256 35 0.059
bone development disease DOID:0080006 55 0.059
sensory system disease DOID:0050155 203 0.032
nervous system disease DOID:863 431 0.032
eye and adnexa disease DOID:1492 150 0.030
osteogenesis imperfecta DOID:12347 13 0.022
eye disease DOID:5614 149 0.021
retinal disease DOID:5679 118 0.018