Homo sapiens

0 known processes

AFF1

AF4/FMR2 family, member 1

(Aliases: AF4,PBM1,MGC134969,MLLT2)

AFF1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
non canonical wnt signaling pathway GO:0035567 14 0.980
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.874
negative regulation of wnt signaling pathway GO:0030178 69 0.830
hindlimb morphogenesis GO:0035137 2 0.746
snrna transcription from rna polymerase ii promoter GO:0042795 7 0.708
wnt signaling pathway planar cell polarity pathway GO:0060071 5 0.598
chromatin modification GO:0016568 298 0.573
positive regulation of dna templated transcription elongation GO:0032786 18 0.552
establishment of planar polarity GO:0001736 3 0.513
histone h3 acetylation GO:0043966 45 0.455
establishment of tissue polarity GO:0007164 3 0.440
regulation of establishment of planar polarity GO:0090175 5 0.412
embryonic hindlimb morphogenesis GO:0035116 2 0.396
spermatid development GO:0007286 4 0.321
regulation of wnt signaling pathway GO:0030111 123 0.320
canonical wnt signaling pathway GO:0060070 116 0.307
response to abiotic stimulus GO:0009628 336 0.273
internal protein amino acid acetylation GO:0006475 101 0.258
positive regulation of non canonical wnt signaling pathway GO:2000052 3 0.247
regulation of non canonical wnt signaling pathway GO:2000050 4 0.186
internal peptidyl lysine acetylation GO:0018393 97 0.149
embryonic hemopoiesis GO:0035162 4 0.148
erythrocyte development GO:0048821 3 0.144
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.139
cell morphogenesis GO:0000902 296 0.130
morphogenesis of a polarized epithelium GO:0001738 3 0.127
cell development GO:0048468 328 0.119
Fly
histone acetylation GO:0016573 93 0.119
organ morphogenesis GO:0009887 147 0.119
Fly
positive regulation of wnt signaling pathway planar cell polarity pathway GO:2000096 2 0.112
histone methylation GO:0016571 60 0.111
regulation of anatomical structure morphogenesis GO:0022603 286 0.110
cellular amino acid metabolic process GO:0006520 116 0.107
methylation GO:0032259 106 0.107
wnt signaling pathway GO:0016055 156 0.107
histone modification GO:0016570 251 0.106
regulation of cellular amine metabolic process GO:0033238 11 0.099
spermatid differentiation GO:0048515 4 0.085
negative regulation of phosphatase activity GO:0010923 61 0.085
snrna transcription from rna polymerase iii promoter GO:0042796 5 0.078
regulation of cell cycle GO:0051726 393 0.074
cellular ketone metabolic process GO:0042180 80 0.074
actin filament based process GO:0030029 224 0.069
multicellular organismal aging GO:0010259 3 0.068
cellular amine metabolic process GO:0044106 41 0.068
anterior posterior axis specification GO:0009948 2 0.063
tissue morphogenesis GO:0048729 96 0.062
cellular macromolecule catabolic process GO:0044265 380 0.061
positive regulation of transport GO:0051050 336 0.059
actin filament organization GO:0007015 128 0.058
phosphorylation of rna polymerase ii c terminal domain GO:0070816 3 0.058
positive regulation of cellular amine metabolic process GO:0033240 7 0.057
negative regulation of cell proliferation GO:0008285 228 0.057
negative regulation of catalytic activity GO:0043086 335 0.057
post embryonic development GO:0009791 2 0.057
negative regulation of protein metabolic process GO:0051248 391 0.054
limb morphogenesis GO:0035108 16 0.054
snrna transcription GO:0009301 8 0.054
response to cytokine GO:0034097 232 0.052
peptidyl lysine methylation GO:0018022 37 0.052
response to tumor necrosis factor GO:0034612 76 0.052
biological adhesion GO:0022610 331 0.051
chromatin organization GO:0006325 351 0.049
negative regulation of phosphate metabolic process GO:0045936 267 0.048
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.048
somatic stem cell maintenance GO:0035019 4 0.047
protein modification by small protein conjugation GO:0032446 342 0.046
determination of adult lifespan GO:0008340 2 0.045
telomere maintenance GO:0000723 32 0.045
mitotic cell cycle GO:0000278 326 0.045
negative regulation of hydrolase activity GO:0051346 182 0.044
regulation of response to drug GO:2001023 3 0.044
regulation of response to dna damage stimulus GO:2001020 94 0.044
dna modification GO:0006304 27 0.044
regulation of protein kinase activity GO:0045859 289 0.044
actin cytoskeleton organization GO:0030036 207 0.043
dna repair GO:0006281 198 0.042
histone h4 k8 acetylation GO:0043982 15 0.041
embryonic limb morphogenesis GO:0030326 9 0.041
epithelium development GO:0060429 227 0.041
nucleoside phosphate catabolic process GO:1901292 412 0.040
negative regulation of phosphorylation GO:0042326 174 0.040
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 10 0.039
regulation of cell cycle process GO:0010564 266 0.039
posttranscriptional regulation of gene expression GO:0010608 213 0.038
cell projection organization GO:0030030 252 0.038
regulation of cellular amino acid metabolic process GO:0006521 6 0.038
stem cell differentiation GO:0048863 93 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
peptidyl lysine dimethylation GO:0018027 3 0.037
covalent chromatin modification GO:0016569 254 0.037
regulation of dephosphorylation GO:0035303 96 0.036
jak stat cascade GO:0007259 46 0.035
positive regulation of catabolic process GO:0009896 310 0.035
regulation of cell differentiation GO:0045595 393 0.034
mapk cascade GO:0000165 288 0.034
positive regulation of cell death GO:0010942 263 0.032
response to organic cyclic compound GO:0014070 204 0.032
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.032
amine metabolic process GO:0009308 44 0.031
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.031
regulation of cellular ketone metabolic process GO:0010565 50 0.031
regulation of cellular component biogenesis GO:0044087 281 0.031
cellular component morphogenesis GO:0032989 314 0.031
enzyme linked receptor protein signaling pathway GO:0007167 303 0.031
protein methylation GO:0006479 74 0.031
positive regulation of wnt signaling pathway GO:0030177 54 0.031
cell fate determination GO:0001709 3 0.030
nucleoside catabolic process GO:0009164 408 0.030
positive regulation of cellular component organization GO:0051130 376 0.030
negative regulation of dna replication GO:0008156 29 0.030
regulation of transporter activity GO:0032409 82 0.030
negative regulation of cellular protein metabolic process GO:0032269 353 0.029
viral process GO:0016032 146 0.029
positive regulation of chromatin modification GO:1903310 30 0.029
rho protein signal transduction GO:0007266 26 0.029
histone h4 k16 acetylation GO:0043984 14 0.028
interspecies interaction between organisms GO:0044419 156 0.028
embryonic appendage morphogenesis GO:0035113 9 0.028
cellular macromolecular complex assembly GO:0034622 324 0.028
single organism cellular localization GO:1902580 332 0.028
segmentation GO:0035282 4 0.028
Fly
g1 s transition of mitotic cell cycle GO:0000082 78 0.027
gtp catabolic process GO:0006184 237 0.027
purine ribonucleoside metabolic process GO:0046128 437 0.027
heart morphogenesis GO:0003007 48 0.026
ras protein signal transduction GO:0007265 73 0.026
regulation of protein processing GO:0070613 150 0.026
positive regulation of hydrolase activity GO:0051345 331 0.025
embryo development GO:0009790 123 0.025
Fly
negative regulation of protein modification process GO:0031400 200 0.025
regulation of cellular response to stress GO:0080135 244 0.025
regulation of nucleotide metabolic process GO:0006140 269 0.025
positive regulation of organelle organization GO:0010638 195 0.025
ribonucleoside catabolic process GO:0042454 406 0.024
purine ribonucleotide catabolic process GO:0009154 404 0.024
multi organism cellular process GO:0044764 156 0.024
cellular protein catabolic process GO:0044257 261 0.024
regulation of canonical wnt signaling pathway GO:0060828 88 0.024
locomotory behavior GO:0007626 1 0.023
regulation of protein complex assembly GO:0043254 147 0.023
cellular response to cytokine stimulus GO:0071345 181 0.023
guanosine containing compound catabolic process GO:1901069 239 0.023
mitotic cell cycle phase transition GO:0044772 162 0.023
regulation of histone methylation GO:0031060 16 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.023
single organism reproductive process GO:0044702 98 0.022
regulation of purine nucleotide metabolic process GO:1900542 264 0.022
small gtpase mediated signal transduction GO:0007264 78 0.022
peptidyl lysine modification GO:0018205 144 0.022
nucleotide catabolic process GO:0009166 408 0.021
negative regulation of cell cycle process GO:0010948 121 0.021
neuromuscular junction development GO:0007528 3 0.021
organophosphate catabolic process GO:0046434 430 0.021
single organism carbohydrate metabolic process GO:0044723 193 0.021
reproductive process GO:0022414 106 0.021
morphogenesis of embryonic epithelium GO:0016331 4 0.021
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.021
regulation of chromatin organization GO:1902275 56 0.021
cell adhesion GO:0007155 325 0.021
lipid metabolic process GO:0006629 381 0.021
appendage development GO:0048736 23 0.021
metal ion transport GO:0030001 272 0.021
oocyte development GO:0048599 1 0.021
regulation of nucleoside metabolic process GO:0009118 209 0.020
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.020
anatomical structure formation involved in morphogenesis GO:0048646 284 0.020
positive regulation of endopeptidase activity GO:0010950 84 0.020
cytoplasmic transport GO:0016482 379 0.020
cation transport GO:0006812 331 0.020
negative regulation of stem cell differentiation GO:2000737 22 0.019
actin mediated cell contraction GO:0070252 12 0.019
positive regulation of gtpase activity GO:0043547 166 0.019
regulation of transferase activity GO:0051338 355 0.019
response to biotic stimulus GO:0009607 276 0.019
purine containing compound catabolic process GO:0072523 411 0.019
motor neuron axon guidance GO:0008045 2 0.019
cellular response to dna damage stimulus GO:0006974 379 0.019
protein processing GO:0016485 226 0.019
purine nucleotide catabolic process GO:0006195 405 0.019
positive regulation of gtp catabolic process GO:0033126 166 0.019
positive regulation of protein transport GO:0051222 135 0.019
anatomical structure homeostasis GO:0060249 100 0.019
regulation of dna templated transcription in response to stress GO:0043620 18 0.019
ribonucleotide catabolic process GO:0009261 405 0.019
nervous system development GO:0007399 293 0.018
Fly
regulation of cell morphogenesis GO:0022604 153 0.018
regulation of dna repair GO:0006282 47 0.018
regulation of protein serine threonine kinase activity GO:0071900 179 0.018
regulation of cellular response to growth factor stimulus GO:0090287 76 0.018
actin filament based movement GO:0030048 17 0.018
response to heat GO:0009408 21 0.018
regulation of cytoskeleton organization GO:0051493 177 0.018
Fly
ribonucleoside triphosphate catabolic process GO:0009203 391 0.018
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.018
positive regulation of nucleoside metabolic process GO:0045979 186 0.018
inorganic ion transmembrane transport GO:0098660 231 0.018
immune system development GO:0002520 195 0.018
rna interference GO:0016246 4 0.018
purine nucleoside triphosphate catabolic process GO:0009146 392 0.018
glycosyl compound catabolic process GO:1901658 413 0.018
nucleoside triphosphate catabolic process GO:0009143 394 0.018
regulation of histone acetylation GO:0035065 19 0.018
nucleoside triphosphate metabolic process GO:0009141 422 0.018
compound eye development GO:0048749 1 0.018
Fly
anterior posterior axis specification embryo GO:0008595 2 0.017
microtubule based process GO:0007017 210 0.017
ribonucleoside triphosphate metabolic process GO:0009199 412 0.017
single organism membrane organization GO:0044802 268 0.017
cellular protein complex assembly GO:0043623 188 0.017
negative regulation of mitotic cell cycle GO:0045930 102 0.017
negative regulation of cellular component organization GO:0051129 235 0.017
hemopoiesis GO:0030097 180 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.017
regulation of protein localization GO:0032880 296 0.017
tube morphogenesis GO:0035239 95 0.017
membrane organization GO:0061024 292 0.017
embryonic morphogenesis GO:0048598 85 0.017
cytokine production GO:0001816 247 0.016
transmembrane transport GO:0055085 399 0.016
regulation of establishment of protein localization GO:0070201 242 0.016
hindbrain development GO:0030902 3 0.016
positive regulation of protein phosphorylation GO:0001934 313 0.016
negative regulation of cellular amine metabolic process GO:0033239 3 0.016
cation transmembrane transport GO:0098655 238 0.016
positive regulation of histone modification GO:0031058 29 0.016
stem cell development GO:0048864 69 0.016
cellular response to endogenous stimulus GO:0071495 336 0.016
response to hormone GO:0009725 175 0.016
purine nucleoside catabolic process GO:0006152 398 0.016
positive regulation of nucleotide metabolic process GO:0045981 230 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.016
purine nucleoside triphosphate metabolic process GO:0009144 412 0.016
maintenance of location GO:0051235 112 0.016
tripartite regional subdivision GO:0007351 2 0.016
aorta development GO:0035904 2 0.016
defense response GO:0006952 315 0.016
response to ionizing radiation GO:0010212 65 0.016
stress activated protein kinase signaling cascade GO:0031098 94 0.015
cell part morphogenesis GO:0032990 137 0.015
intracellular protein transport GO:0006886 270 0.015
memory GO:0007613 3 0.015
positive regulation of phosphorylation GO:0042327 394 0.015
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
associative learning GO:0008306 1 0.015
carbohydrate metabolic process GO:0005975 207 0.015
regulation of gene expression epigenetic GO:0040029 73 0.015
protein localization to organelle GO:0033365 280 0.015
dephosphorylation GO:0016311 209 0.015
protein maturation GO:0051604 233 0.015
viral life cycle GO:0019058 132 0.015
establishment of protein localization to organelle GO:0072594 172 0.015
mitotic cell cycle process GO:1903047 286 0.015
regulation of protein transport GO:0051223 213 0.015
adult locomotory behavior GO:0008344 1 0.015
cardiac muscle cell contraction GO:0086003 4 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.014
regulation of cysteine type endopeptidase activity GO:2000116 127 0.014
neuron development GO:0048666 113 0.014
Fly
negative regulation of cell differentiation GO:0045596 171 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
regeneration GO:0031099 4 0.014
regulation of neurotransmitter secretion GO:0046928 3 0.014
system process GO:0003008 349 0.014
Fly
embryonic epithelial tube formation GO:0001838 4 0.014
negative regulation of transferase activity GO:0051348 124 0.014
stem cell division GO:0017145 2 0.014
carbohydrate derivative biosynthetic process GO:1901137 207 0.014
positive regulation of transporter activity GO:0032411 32 0.014
cellular lipid metabolic process GO:0044255 303 0.014
microtubule cytoskeleton organization GO:0000226 176 0.014
negative regulation of dephosphorylation GO:0035305 63 0.014
mating GO:0007618 1 0.014
cellular response to drug GO:0035690 27 0.014
apoptotic signaling pathway GO:0097190 268 0.014
negative regulation of organelle organization GO:0010639 126 0.014
blood vessel morphogenesis GO:0048514 162 0.014
regulation of nucleocytoplasmic transport GO:0046822 98 0.014
purine ribonucleoside catabolic process GO:0046130 398 0.014
protein catabolic process GO:0030163 325 0.014
peripheral nervous system development GO:0007422 2 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.014
t cell differentiation in thymus GO:0033077 4 0.014
epithelial cell differentiation GO:0030855 141 0.014
nucleocytoplasmic transport GO:0006913 176 0.013
somitogenesis GO:0001756 2 0.013
myeloid cell differentiation GO:0030099 117 0.013
histone h3 k4 trimethylation GO:0080182 7 0.013
tube closure GO:0060606 3 0.013
reproduction GO:0000003 63 0.013
protein stabilization GO:0050821 64 0.013
forebrain generation of neurons GO:0021872 3 0.013
positive regulation of transcription from rna polymerase iii promoter GO:0045945 10 0.013
positive regulation of apoptotic process GO:0043065 246 0.013
gtp metabolic process GO:0046039 239 0.013
response to oxygen containing compound GO:1901700 369 0.013
cellular component disassembly GO:0022411 92 0.013
ion homeostasis GO:0050801 230 0.013
regulation of cell growth GO:0001558 135 0.013
ion transmembrane transport GO:0034220 338 0.013
protein ubiquitination GO:0016567 314 0.013
eye photoreceptor cell differentiation GO:0001754 2 0.013
Fly
cell projection assembly GO:0030031 126 0.013
meiosis i GO:0007127 4 0.013
response to lipid GO:0033993 206 0.013
inorganic cation transmembrane transport GO:0098662 194 0.013
regulation of multi organism process GO:0043900 157 0.013
neuron differentiation GO:0030182 138 0.013
Fly
regulation of ras protein signal transduction GO:0046578 155 0.013
cell cycle g1 s phase transition GO:0044843 80 0.013
reactive oxygen species biosynthetic process GO:1903409 4 0.013
positive regulation of cell differentiation GO:0045597 211 0.013
protein localization to membrane GO:0072657 160 0.013
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
regulation of dna metabolic process GO:0051052 153 0.013
secretion by cell GO:0032940 226 0.013
monovalent inorganic cation transport GO:0015672 128 0.012
regulation of cellular component movement GO:0051270 334 0.012
organonitrogen compound biosynthetic process GO:1901566 200 0.012
organophosphate biosynthetic process GO:0090407 163 0.012
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
female gamete generation GO:0007292 2 0.012
protein targeting GO:0006605 187 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
negative regulation of programmed cell death GO:0043069 321 0.012
cellular response to glucocorticoid stimulus GO:0071385 4 0.012
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.012
establishment of protein localization to membrane GO:0090150 121 0.012
synaptic vesicle exocytosis GO:0016079 3 0.012
guanosine containing compound metabolic process GO:1901068 244 0.012
regulation of chromosome organization GO:0033044 103 0.012
cell division GO:0051301 168 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
negative regulation of endopeptidase activity GO:0010951 84 0.012
neural tube closure GO:0001843 3 0.012
regulation of proteolysis GO:0030162 293 0.012
positive regulation of developmental process GO:0051094 314 0.012
response to axon injury GO:0048678 1 0.012
organelle assembly GO:0070925 176 0.012
regulation of ras gtpase activity GO:0032318 128 0.012
regulation of cell motility GO:2000145 299 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.012
positive regulation of peptidase activity GO:0010952 88 0.012
response to growth factor GO:0070848 205 0.012
vesicle mediated transport GO:0016192 371 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
dna integrity checkpoint GO:0031570 71 0.011
protein alkylation GO:0008213 74 0.011
glycoprotein metabolic process GO:0009100 110 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
dna catabolic process endonucleolytic GO:0000737 37 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.011
negative regulation of multicellular organismal process GO:0051241 317 0.011
visual behavior GO:0007632 2 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
Fly
regulation of cytokine production GO:0001817 232 0.011
brain development GO:0007420 97 0.011
regulation of small gtpase mediated signal transduction GO:0051056 156 0.011
chemical homeostasis GO:0048878 306 0.011
positive regulation of synaptic transmission GO:0050806 4 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
positive regulation of programmed cell death GO:0043068 249 0.011
oligosaccharide biosynthetic process GO:0009312 3 0.011
regulation of intracellular transport GO:0032386 195 0.011
ossification GO:0001503 121 0.011
visual learning GO:0008542 1 0.011
regulation of reactive oxygen species metabolic process GO:2000377 41 0.011
single organism cell adhesion GO:0098602 179 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
endomembrane system organization GO:0010256 196 0.011
regulation of microtubule based process GO:0032886 74 0.011
sleep GO:0030431 2 0.011
negative regulation of kinase activity GO:0033673 106 0.011
anion transport GO:0006820 161 0.011
limb development GO:0060173 23 0.011
modification dependent protein catabolic process GO:0019941 209 0.011
response to wounding GO:0009611 168 0.011
cellular response to oxygen containing compound GO:1901701 276 0.011
innate immune response GO:0045087 178 0.011
negative regulation of proteolysis GO:0045861 132 0.011
neuroblast proliferation GO:0007405 4 0.011
regulation of kinase activity GO:0043549 314 0.011
inner ear morphogenesis GO:0042472 4 0.011
appendage morphogenesis GO:0035107 16 0.011
organelle localization GO:0051640 84 0.011
positive regulation of cellular catabolic process GO:0031331 284 0.011
negative regulation of cell death GO:0060548 345 0.011
rna processing GO:0006396 255 0.011
Human
cellular response to nitrogen compound GO:1901699 144 0.011
negative regulation of protein processing GO:0010955 142 0.011
response to nitrogen compound GO:1901698 184 0.011
nuclear transport GO:0051169 179 0.011
positive regulation of immune system process GO:0002684 283 0.011
organelle fission GO:0048285 149 0.011
regulation of cell development GO:0060284 161 0.011
positive regulation of intracellular transport GO:0032388 104 0.011
negative regulation of dna metabolic process GO:0051053 57 0.011
cell aging GO:0007569 52 0.011
regulation of viral genome replication GO:0045069 48 0.010
reactive oxygen species metabolic process GO:0072593 75 0.010
regulation of gtpase activity GO:0043087 180 0.010
regulation of rho protein signal transduction GO:0035023 79 0.010
spinal cord development GO:0021510 4 0.010
thymus development GO:0048538 3 0.010
endocytosis GO:0006897 159 0.010
salivary gland morphogenesis GO:0007435 4 0.010
regulation of anatomical structure size GO:0090066 101 0.010
Fly
immune response GO:0006955 307 0.010
tissue regeneration GO:0042246 3 0.010
response to fungus GO:0009620 4 0.010
melanin metabolic process GO:0006582 1 0.010
regulation of glial cell differentiation GO:0045685 3 0.010
heart formation GO:0060914 2 0.010
ameboidal type cell migration GO:0001667 135 0.010
positive regulation of transferase activity GO:0051347 227 0.010
plasma membrane organization GO:0007009 115 0.010
dna catabolic process GO:0006308 49 0.010
regulation of mapk cascade GO:0043408 262 0.010

AFF1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.056
cancer DOID:162 167 0.045
organ system cancer DOID:0050686 164 0.032
disease of metabolism DOID:0014667 295 0.027
inherited metabolic disorder DOID:655 242 0.023
musculoskeletal system disease DOID:17 223 0.023
myopathy DOID:423 104 0.016
muscular disease DOID:0080000 114 0.016
muscle tissue disease DOID:66 113 0.016
sensory system disease DOID:0050155 203 0.013
nervous system disease DOID:863 431 0.013
immune system cancer DOID:0060083 36 0.013
hematologic cancer DOID:2531 36 0.013
immune system disease DOID:2914 155 0.012
eye and adnexa disease DOID:1492 150 0.012
eye disease DOID:5614 149 0.012
connective tissue disease DOID:65 109 0.012
carbohydrate metabolic disorder DOID:2978 55 0.012
bone disease DOID:0080001 88 0.011
hematopoietic system disease DOID:74 100 0.010
cardiovascular system disease DOID:1287 106 0.010
central nervous system disease DOID:331 186 0.010