Homo sapiens

36 known processes

ALOX5

arachidonate 5-lipoxygenase

(Aliases: 5LPG,LOG5,MGC163204,5-LO,5-LOX)

ALOX5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
defense response GO:0006952 315 0.912
Mouse Rat
complement receptor mediated signaling pathway GO:0002430 3 0.795
defense response to fungus GO:0050832 4 0.673
response to other organism GO:0051707 261 0.646
response to external biotic stimulus GO:0043207 261 0.642
response to fungus GO:0009620 4 0.568
lipoxygenase pathway GO:0019372 4 0.511
Human Rat
defense response to other organism GO:0098542 129 0.504
response to biotic stimulus GO:0009607 276 0.492
positive regulation of immune system process GO:0002684 283 0.470
immune response GO:0006955 307 0.455
regulation of defense response GO:0031347 154 0.437
leukotriene metabolic process GO:0006691 10 0.351
response to cytokine GO:0034097 232 0.330
Human
regulation of locomotion GO:0040012 329 0.298
cytokine production GO:0001816 247 0.257
Human
leukocyte migration GO:0050900 107 0.248
inflammatory response GO:0006954 79 0.229
Mouse Rat
taxis GO:0042330 157 0.227
lipid metabolic process GO:0006629 381 0.226
divalent inorganic cation homeostasis GO:0072507 136 0.217
leukotriene production involved in inflammatory response GO:0002540 1 0.211
Mouse
lipid biosynthetic process GO:0008610 177 0.208
g protein coupled receptor signaling pathway GO:0007186 207 0.206
cellular lipid metabolic process GO:0044255 303 0.205
activation of immune response GO:0002253 114 0.196
cell chemotaxis GO:0060326 112 0.195
positive regulation of protein phosphorylation GO:0001934 313 0.189
cellular response to endogenous stimulus GO:0071495 336 0.189
amine metabolic process GO:0009308 44 0.187
leukocyte chemotaxis GO:0030595 76 0.187
regulation of mapk cascade GO:0043408 262 0.179
Human
small molecule biosynthetic process GO:0044283 157 0.173
regulation of immune response GO:0050776 201 0.170
chemotaxis GO:0006935 157 0.157
positive regulation of locomotion GO:0040017 186 0.155
myeloid leukocyte migration GO:0097529 62 0.153
fatty acid metabolic process GO:0006631 115 0.153
regulation of leukocyte migration GO:0002685 63 0.151
regulation of cellular component movement GO:0051270 334 0.149
nitrogen compound transport GO:0071705 191 0.148
regulation of epithelial cell migration GO:0010632 93 0.148
positive regulation of defense response GO:0031349 87 0.146
response to oxygen containing compound GO:1901700 369 0.145
cellular amino acid metabolic process GO:0006520 116 0.144
cellular homeostasis GO:0019725 196 0.143
biological adhesion GO:0022610 331 0.142
Human
vesicle mediated transport GO:0016192 371 0.138
secretion GO:0046903 254 0.134
Human
ion homeostasis GO:0050801 230 0.132
icosanoid metabolic process GO:0006690 35 0.132
positive regulation of phosphorylation GO:0042327 394 0.129
Human
immune response regulating signaling pathway GO:0002764 97 0.127
positive regulation of cell motility GO:2000147 177 0.127
protein maturation GO:0051604 233 0.124
positive regulation of cellular component movement GO:0051272 181 0.122
regulation of anatomical structure morphogenesis GO:0022603 286 0.120
monocarboxylic acid biosynthetic process GO:0072330 67 0.119
cellular ion homeostasis GO:0006873 168 0.117
positive regulation of transport GO:0051050 336 0.115
Human
regulation of cytokine production GO:0001817 232 0.112
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.111
monocarboxylic acid metabolic process GO:0032787 185 0.110
ras protein signal transduction GO:0007265 73 0.109
cellular metal ion homeostasis GO:0006875 146 0.107
protein processing GO:0016485 226 0.103
regulation of protein processing GO:0070613 150 0.103
positive regulation of cell migration GO:0030335 172 0.101
cellular ketone metabolic process GO:0042180 80 0.100
apoptotic signaling pathway GO:0097190 268 0.100
response to metal ion GO:0010038 84 0.099
Human
secretion by cell GO:0032940 226 0.098
Human
behavior GO:0007610 112 0.098
negative regulation of protein metabolic process GO:0051248 391 0.096
cellular component morphogenesis GO:0032989 314 0.096
regulation of response to external stimulus GO:0032101 222 0.095
response to wounding GO:0009611 168 0.094
unsaturated fatty acid metabolic process GO:0033559 37 0.094
immune response activating signal transduction GO:0002757 90 0.094
negative regulation of catalytic activity GO:0043086 335 0.093
protein homooligomerization GO:0051260 100 0.092
regulation of innate immune response GO:0045088 97 0.089
cellular response to oxygen containing compound GO:1901701 276 0.086
negative regulation of cellular protein metabolic process GO:0032269 353 0.085
response to growth factor GO:0070848 205 0.085
regulation of peptidase activity GO:0052547 180 0.084
mapk cascade GO:0000165 288 0.083
Human
innate immune response GO:0045087 178 0.082
fatty acid derivative biosynthetic process GO:1901570 18 0.082
system process GO:0003008 349 0.080
Rat
regulation of hormone levels GO:0010817 125 0.079
female gamete generation GO:0007292 2 0.079
protein oligomerization GO:0051259 173 0.077
regulation of protein transport GO:0051223 213 0.076
Human
organic acid biosynthetic process GO:0016053 97 0.075
leukocyte activation GO:0045321 164 0.075
cellular chemical homeostasis GO:0055082 180 0.074
associative learning GO:0008306 1 0.072
endodermal cell fate commitment GO:0001711 4 0.072
regulation of cellular ketone metabolic process GO:0010565 50 0.072
tissue migration GO:0090130 119 0.072
positive regulation of protein kinase activity GO:0045860 190 0.071
response to lipid GO:0033993 206 0.071
regulation of endopeptidase activity GO:0052548 170 0.071
cellular amine metabolic process GO:0044106 41 0.070
cellular response to growth factor stimulus GO:0071363 197 0.070
positive regulation of nucleotide metabolic process GO:0045981 230 0.070
complement activation alternative pathway GO:0006957 1 0.069
memory GO:0007613 3 0.068
neuromuscular junction development GO:0007528 3 0.068
purine containing compound catabolic process GO:0072523 411 0.067
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.066
regulation of proteolysis GO:0030162 293 0.065
positive regulation of proteolysis GO:0045862 142 0.064
positive regulation of transferase activity GO:0051347 227 0.063
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.063
purine nucleotide catabolic process GO:0006195 405 0.063
positive regulation of immune response GO:0050778 159 0.062
response to organonitrogen compound GO:0010243 156 0.061
purine ribonucleoside metabolic process GO:0046128 437 0.061
cell activation GO:0001775 213 0.060
nucleotide catabolic process GO:0009166 408 0.060
response to molecule of bacterial origin GO:0002237 82 0.060
response to bacterium GO:0009617 144 0.060
negative regulation of programmed cell death GO:0043069 321 0.059
negative regulation of cellular amine metabolic process GO:0033239 3 0.059
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.059
regulation of cellular amine metabolic process GO:0033238 11 0.058
regulation of leukocyte activation GO:0002694 115 0.058
oxidation reduction process GO:0055114 396 0.058
regulation of humoral immune response mediated by circulating immunoglobulin GO:0002923 3 0.057
regulation of apoptotic signaling pathway GO:2001233 175 0.057
regulation of cell differentiation GO:0045595 393 0.057
Human
hemopoiesis GO:0030097 180 0.057
response to calcium ion GO:0051592 46 0.057
Human
granulocyte migration GO:0097530 40 0.057
positive regulation of kinase activity GO:0033674 204 0.057
positive regulation of hydrolase activity GO:0051345 331 0.057
negative regulation of immune system process GO:0002683 136 0.056
negative regulation of protein processing GO:0010955 142 0.056
fatty acid biosynthetic process GO:0006633 46 0.056
cardiovascular system development GO:0072358 262 0.055
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.054
immune system development GO:0002520 195 0.054
negative regulation of cell death GO:0060548 345 0.054
regulation of response to wounding GO:1903034 101 0.054
lymphocyte activation GO:0046649 133 0.054
negative regulation of proteolysis GO:0045861 132 0.054
negative regulation of apoptotic process GO:0043066 316 0.054
regulation of cell development GO:0060284 161 0.053
cell morphogenesis GO:0000902 296 0.053
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.052
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.052
response to abiotic stimulus GO:0009628 336 0.052
Rat
cellular response to lipid GO:0071396 127 0.052
regulation of protein secretion GO:0050708 86 0.052
Human
negative regulation of multicellular organismal process GO:0051241 317 0.052
positive regulation of acute inflammatory response GO:0002675 2 0.051
myeloid cell differentiation GO:0030099 117 0.051
ribonucleoside catabolic process GO:0042454 406 0.051
negative regulation of hydrolase activity GO:0051346 182 0.051
regulation of protein maturation GO:1903317 150 0.050
acute inflammatory response GO:0002526 21 0.049
Rat
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.049
negative regulation of peptidase activity GO:0010466 91 0.048
response to transforming growth factor beta GO:0071559 94 0.047
regulation of kinase activity GO:0043549 314 0.047
purine nucleoside triphosphate metabolic process GO:0009144 412 0.047
blood vessel morphogenesis GO:0048514 162 0.047
regulation of secretion GO:0051046 194 0.047
Human
blood vessel development GO:0001568 172 0.047
positive regulation of cytokine production GO:0001819 167 0.047
Human
nucleoside phosphate catabolic process GO:1901292 412 0.046
enzyme linked receptor protein signaling pathway GO:0007167 303 0.046
negative regulation of phosphorus metabolic process GO:0010563 267 0.045
regulation of cellular amino acid metabolic process GO:0006521 6 0.045
ribonucleoside triphosphate metabolic process GO:0009199 412 0.044
protein autophosphorylation GO:0046777 123 0.044
regulation of inflammatory response GO:0050727 46 0.044
negative regulation of protein maturation GO:1903318 142 0.043
hematopoietic or lymphoid organ development GO:0048534 186 0.043
regulation of protein kinase activity GO:0045859 289 0.043
peptide transport GO:0015833 74 0.043
cellular divalent inorganic cation homeostasis GO:0072503 128 0.043
chemical homeostasis GO:0048878 306 0.043
positive regulation of cell proliferation GO:0008284 301 0.042
positive regulation of secretion GO:0051047 116 0.042
Human
positive regulation of apoptotic process GO:0043065 246 0.042
amide transport GO:0042886 76 0.041
dephosphorylation GO:0016311 209 0.041
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.041
response to organic cyclic compound GO:0014070 204 0.041
actin filament based process GO:0030029 224 0.041
regulation of secretion by cell GO:1903530 177 0.041
Human
oogenesis GO:0048477 2 0.041
positive regulation of peptidase activity GO:0010952 88 0.040
hormone transport GO:0009914 68 0.040
negative regulation of immune response GO:0050777 40 0.040
endocytosis GO:0006897 159 0.040
maintenance of location GO:0051235 112 0.039
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.039
cation homeostasis GO:0055080 189 0.039
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.039
negative regulation of transport GO:0051051 176 0.038
response to inorganic substance GO:0010035 127 0.038
Human
erk1 and erk2 cascade GO:0070371 104 0.038
Human
negative regulation of cellular component organization GO:0051129 235 0.038
negative regulation of developmental process GO:0051093 247 0.037
regulation of purine nucleotide metabolic process GO:1900542 264 0.037
leukocyte mediated immunity GO:0002443 59 0.037
negative regulation of endopeptidase activity GO:0010951 84 0.037
regulation of transferase activity GO:0051338 355 0.037
anatomical structure formation involved in morphogenesis GO:0048646 284 0.037
nucleoside catabolic process GO:0009164 408 0.036
cellular cation homeostasis GO:0030003 163 0.036
regulation of mononuclear cell proliferation GO:0032944 65 0.036
regulation of cytokine secretion GO:0050707 57 0.036
Human
positive regulation of mapk cascade GO:0043410 190 0.036
Human
multicellular organismal aging GO:0010259 3 0.036
cellular modified amino acid metabolic process GO:0006575 64 0.035
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.035
positive regulation of cell death GO:0010942 263 0.035
positive regulation of endopeptidase activity GO:0010950 84 0.035
metal ion transport GO:0030001 272 0.035
actin filament organization GO:0007015 128 0.035
regulation of establishment of protein localization GO:0070201 242 0.035
Human
positive regulation of secretion by cell GO:1903532 108 0.035
Human
positive regulation of cellular component organization GO:0051130 376 0.034
single organism membrane organization GO:0044802 268 0.034
regulation of intracellular transport GO:0032386 195 0.034
positive regulation of cell projection organization GO:0031346 64 0.033
brain development GO:0007420 97 0.033
small gtpase mediated signal transduction GO:0007264 78 0.033
positive regulation of cellular catabolic process GO:0031331 284 0.033
negative regulation of phosphate metabolic process GO:0045936 267 0.033
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.033
long term memory GO:0007616 2 0.033
negative regulation of protein phosphorylation GO:0001933 140 0.032
leukocyte differentiation GO:0002521 98 0.032
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.032
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.032
regulation of cell projection organization GO:0031344 107 0.032
regulation of cellular component biogenesis GO:0044087 281 0.032
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.032
positive regulation of catabolic process GO:0009896 310 0.031
cell morphogenesis involved in differentiation GO:0000904 144 0.031
positive regulation of developmental process GO:0051094 314 0.031
Human
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.031
immune effector process GO:0002252 159 0.031
determination of adult lifespan GO:0008340 2 0.031
mitotic cell cycle GO:0000278 326 0.031
organophosphate catabolic process GO:0046434 430 0.031
ameboidal type cell migration GO:0001667 135 0.030
actin filament bundle assembly GO:0051017 54 0.030
response to nitrogen compound GO:1901698 184 0.030
positive regulation of protein transport GO:0051222 135 0.030
Human
regulation of cysteine type endopeptidase activity GO:2000116 127 0.030
transmembrane transport GO:0055085 399 0.029
ribonucleoside triphosphate catabolic process GO:0009203 391 0.029
nucleoside triphosphate catabolic process GO:0009143 394 0.029
metal ion homeostasis GO:0055065 169 0.029
cation transport GO:0006812 331 0.029
regulation of cell motility GO:2000145 299 0.029
negative regulation of phosphorylation GO:0042326 174 0.028
regulation of vesicle mediated transport GO:0060627 130 0.028
regulation of membrane potential GO:0042391 95 0.028
mitotic cell cycle process GO:1903047 286 0.028
purine ribonucleotide catabolic process GO:0009154 404 0.028
cellular response to nitrogen compound GO:1901699 144 0.028
positive regulation of cell differentiation GO:0045597 211 0.028
Human
response to peptide GO:1901652 65 0.028
regulation of cytoplasmic transport GO:1903649 149 0.027
positive regulation of gtp catabolic process GO:0033126 166 0.027
negative regulation of intracellular signal transduction GO:1902532 183 0.027
positive regulation of response to external stimulus GO:0032103 88 0.027
regulation of purine nucleotide catabolic process GO:0033121 205 0.027
glycosyl compound catabolic process GO:1901658 413 0.027
regulation of behavior GO:0050795 82 0.027
single organism cellular localization GO:1902580 332 0.027
positive regulation of behavior GO:0048520 60 0.026
post embryonic development GO:0009791 2 0.026
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.026
regulation of cell migration GO:0030334 289 0.026
negative regulation of growth GO:0045926 97 0.026
Human
organelle assembly GO:0070925 176 0.026
positive regulation of programmed cell death GO:0043068 249 0.026
peptidyl tyrosine phosphorylation GO:0018108 170 0.026
cytoplasmic transport GO:0016482 379 0.025
negative regulation of secretion by cell GO:1903531 52 0.025
response to axon injury GO:0048678 1 0.025
purine nucleoside catabolic process GO:0006152 398 0.025
signal transduction by phosphorylation GO:0023014 297 0.025
Human
hormone secretion GO:0046879 65 0.025
salivary gland morphogenesis GO:0007435 4 0.024
regulation of t cell activation GO:0050863 77 0.024
regulation of leukocyte chemotaxis GO:0002688 46 0.024
regulation of cell cycle process GO:0010564 266 0.024
regulation of acute inflammatory response GO:0002673 13 0.024
cellular response to organonitrogen compound GO:0071417 124 0.024
cytokine mediated signaling pathway GO:0019221 109 0.024
cell projection organization GO:0030030 252 0.024
calcium ion transport GO:0006816 147 0.024
cell part morphogenesis GO:0032990 137 0.024
negative regulation of transferase activity GO:0051348 124 0.023
vasculature development GO:0001944 181 0.023
circulatory system development GO:0072359 262 0.023
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.023
cytosolic calcium ion homeostasis GO:0051480 89 0.023
endothelial cell migration GO:0043542 86 0.023
regulation of immune effector process GO:0002697 91 0.023
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.023
organ morphogenesis GO:0009887 147 0.022
regulation of protein serine threonine kinase activity GO:0071900 179 0.022
carbohydrate metabolic process GO:0005975 207 0.022
cytokine secretion GO:0050663 64 0.022
Human
peptidyl tyrosine modification GO:0018212 170 0.022
cell junction assembly GO:0034329 67 0.022
negative regulation of protein modification process GO:0031400 200 0.022
response to drug GO:0042493 81 0.022
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.022
complement component c5a signaling pathway GO:0038178 1 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.021
positive regulation of leukocyte chemotaxis GO:0002690 38 0.021
inositol lipid mediated signaling GO:0048017 55 0.021
positive regulation of innate immune response GO:0045089 79 0.021
generation of neurons GO:0048699 152 0.021
regulation of erk1 and erk2 cascade GO:0070372 99 0.021
Human
positive regulation of nucleoside metabolic process GO:0045979 186 0.021
regulation of small gtpase mediated signal transduction GO:0051056 156 0.021
lymphocyte proliferation GO:0046651 70 0.021
early endosome to late endosome transport GO:0045022 21 0.021
regulation of protein complex assembly GO:0043254 147 0.021
angiogenesis GO:0001525 147 0.020
regulation of granulocyte chemotaxis GO:0071622 16 0.020
extrinsic apoptotic signaling pathway GO:0097191 119 0.020
intrinsic apoptotic signaling pathway GO:0097193 127 0.020
cellular response to lipopolysaccharide GO:0071222 57 0.020
regulation of cellular response to stress GO:0080135 244 0.020
divalent metal ion transport GO:0070838 152 0.020
cellular response to metal ion GO:0071248 43 0.020
Human
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.020
cellular response to organic cyclic compound GO:0071407 127 0.020
cellular response to cytokine stimulus GO:0071345 181 0.020
Human
cell cell junction organization GO:0045216 69 0.020
regulation of rho gtpase activity GO:0032319 66 0.020
regulation of blood circulation GO:1903522 59 0.019
Rat
regulation of ion transport GO:0043269 189 0.019
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.019
regulation of protein localization GO:0032880 296 0.019
Human
signal release GO:0023061 70 0.019
peptide hormone secretion GO:0030072 50 0.019
cation transmembrane transport GO:0098655 238 0.019
positive regulation of apoptotic signaling pathway GO:2001235 70 0.019
response to lipopolysaccharide GO:0032496 70 0.019
positive regulation of ras gtpase activity GO:0032320 117 0.019
regulation of lymphocyte activation GO:0051249 103 0.019
neurological system process GO:0050877 163 0.019
Rat
pattern recognition receptor signaling pathway GO:0002221 48 0.019
positive regulation of lymphocyte activation GO:0051251 73 0.019
cellular response to inorganic substance GO:0071241 45 0.019
Human
regulation of hormone secretion GO:0046883 57 0.019
positive regulation of cellular amine metabolic process GO:0033240 7 0.018
positive regulation of leukocyte activation GO:0002696 80 0.018
protein localization to organelle GO:0033365 280 0.018
regulation of lymphocyte proliferation GO:0050670 64 0.018
regulation of ras protein signal transduction GO:0046578 155 0.018
negative regulation of cytokine production GO:0001818 82 0.018
chromatin modification GO:0016568 298 0.018
activation of protein kinase activity GO:0032147 90 0.018
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.018
calcium ion homeostasis GO:0055074 122 0.018
cell junction organization GO:0034330 79 0.018
sulfur compound metabolic process GO:0006790 101 0.018
positive regulation of nucleotide catabolic process GO:0030813 185 0.018
positive regulation of interferon gamma production GO:0032729 26 0.018
histone modification GO:0016570 251 0.017
regulation of cell adhesion GO:0030155 166 0.017
Human
negative regulation of cell cycle GO:0045786 193 0.017
Human
response to decreased oxygen levels GO:0036293 96 0.017
innate immune response activating signal transduction GO:0002758 48 0.017
guanosine containing compound metabolic process GO:1901068 244 0.017
peptide secretion GO:0002790 51 0.017
negative regulation of organelle organization GO:0010639 126 0.017
anatomical structure homeostasis GO:0060249 100 0.017
actin cytoskeleton organization GO:0030036 207 0.017
positive regulation of myeloid leukocyte mediated immunity GO:0002888 1 0.017
cellular macromolecule catabolic process GO:0044265 380 0.017
negative regulation of apoptotic signaling pathway GO:2001234 97 0.017
spermatid differentiation GO:0048515 4 0.017
adherens junction organization GO:0034332 36 0.017
ion transmembrane transport GO:0034220 338 0.016
negative regulation of cell proliferation GO:0008285 228 0.016
Human
regulation of system process GO:0044057 101 0.016
Rat
positive regulation of cell activation GO:0050867 81 0.016
antigen receptor mediated signaling pathway GO:0050851 38 0.016
negative regulation of protein complex assembly GO:0031333 43 0.016
positive regulation of cell adhesion GO:0045785 84 0.016
Human
posttranscriptional regulation of gene expression GO:0010608 213 0.016
protein localization to membrane GO:0072657 160 0.016
response to nutrient levels GO:0031667 81 0.016
Rat
negative regulation of cell migration GO:0030336 102 0.016
actin filament bundle organization GO:0061572 54 0.016
activation of cysteine type endopeptidase activity GO:0097202 57 0.016
regulation of dna metabolic process GO:0051052 153 0.016
endosomal transport GO:0016197 129 0.016
cell projection morphogenesis GO:0048858 129 0.016
cell projection assembly GO:0030031 126 0.015
reactive oxygen species biosynthetic process GO:1903409 4 0.015
atp metabolic process GO:0046034 176 0.015
regulation of angiogenesis GO:0045765 92 0.015
regulation of calcium ion transport GO:0051924 79 0.015
stress fiber assembly GO:0043149 40 0.015
organophosphate biosynthetic process GO:0090407 163 0.015
negative regulation of secretion GO:0051048 58 0.015
inorganic ion transmembrane transport GO:0098660 231 0.015
regulation of interferon gamma production GO:0032649 36 0.015
neurogenesis GO:0022008 169 0.015
regulation of organelle assembly GO:1902115 40 0.015
phospholipid metabolic process GO:0006644 99 0.015
single organism carbohydrate metabolic process GO:0044723 193 0.015
anion transport GO:0006820 161 0.015
activation of innate immune response GO:0002218 55 0.015
positive regulation of intracellular transport GO:0032388 104 0.015
guanosine containing compound catabolic process GO:1901069 239 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.015
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.015
cellular macromolecular complex assembly GO:0034622 324 0.015
response to oxygen levels GO:0070482 100 0.015
Rat
growth GO:0040007 202 0.015
Human
jak stat cascade GO:0007259 46 0.015
regulation of lipid metabolic process GO:0019216 96 0.015
cellular response to abiotic stimulus GO:0071214 117 0.015
cell cycle phase transition GO:0044770 173 0.015
negative regulation of alpha beta t cell activation GO:0046636 3 0.015
defense response to gram positive bacterium GO:0050830 29 0.014
nerve development GO:0021675 4 0.014
regulation of ras gtpase activity GO:0032318 128 0.014
t cell receptor signaling pathway GO:0050852 21 0.014
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.014
Human
cellular response to external stimulus GO:0071496 111 0.014
regulation of mitotic cell cycle GO:0007346 189 0.014
multicellular organismal homeostasis GO:0048871 67 0.014
positive regulation of cytoskeleton organization GO:0051495 83 0.014
cell substrate adhesion GO:0031589 132 0.014
Human
negative regulation of locomotion GO:0040013 118 0.014
b cell activation GO:0042113 33 0.014
regeneration GO:0031099 4 0.014
negative regulation of kinase activity GO:0033673 106 0.014
cellular response to dna damage stimulus GO:0006974 379 0.014
response to hormone GO:0009725 175 0.014
defense response to bacterium GO:0042742 63 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.014
muscle system process GO:0003012 81 0.014
positive regulation of macrophage chemotaxis GO:0010759 3 0.014
blastoderm segmentation GO:0007350 2 0.014
alcohol metabolic process GO:0006066 114 0.014
positive regulation of lipid metabolic process GO:0045834 50 0.014
regulation of neurogenesis GO:0050767 82 0.014
positive regulation of cell development GO:0010720 92 0.014
zymogen activation GO:0031638 70 0.014
regulation of mitochondrial membrane potential GO:0051881 23 0.014
regulation of neuron differentiation GO:0045664 70 0.014
head development GO:0060322 108 0.014
rho protein signal transduction GO:0007266 26 0.014
negative regulation of cell motility GO:2000146 104 0.014
chromatin organization GO:0006325 351 0.014
mast cell degranulation GO:0043303 4 0.013
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.013
regulation of cellular response to growth factor stimulus GO:0090287 76 0.013
organic anion transport GO:0015711 103 0.013
response to alcohol GO:0097305 64 0.013
interferon gamma production GO:0032609 39 0.013
cellular calcium ion homeostasis GO:0006874 117 0.013
regulation of cell substrate adhesion GO:0010810 68 0.013
Human
carbohydrate derivative biosynthetic process GO:1901137 207 0.013
steroid metabolic process GO:0008202 94 0.013
adaptive immune response GO:0002250 49 0.013
intracellular protein transport GO:0006886 270 0.013
mast cell activation involved in immune response GO:0002279 4 0.013
nucleocytoplasmic transport GO:0006913 176 0.013
sensory perception GO:0007600 103 0.013
Rat

ALOX5 disease predictions

Disease DO term ID Size Probability Func Analog Org
vascular disease DOID:178 25 0.124
cardiovascular system disease DOID:1287 106 0.124
disease of metabolism DOID:0014667 295 0.035
artery disease DOID:0050828 23 0.030
immune system disease DOID:2914 155 0.024
cerebrovascular disease DOID:6713 8 0.023
inherited metabolic disorder DOID:655 242 0.022
cancer DOID:162 167 0.022
disease of cellular proliferation DOID:14566 174 0.022
sensory system disease DOID:0050155 203 0.018
nervous system disease DOID:863 431 0.018
eye and adnexa disease DOID:1492 150 0.017
organ system cancer DOID:0050686 164 0.016
eye disease DOID:5614 149 0.015