Homo sapiens

18 known processes

ANAPC4

anaphase promoting complex subunit 4

(Aliases: APC4)

ANAPC4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein k11 linked ubiquitination GO:0070979 24 1.000
regulation of mitotic metaphase anaphase transition GO:0030071 26 1.000
protein polyubiquitination GO:0000209 110 1.000
protein ubiquitination GO:0016567 314 1.000
protein modification by small protein conjugation GO:0032446 342 1.000
regulation of sister chromatid segregation GO:0033045 27 1.000
regulation of mitotic sister chromatid separation GO:0010965 27 1.000
mitotic sister chromatid separation GO:0051306 18 1.000
regulation of proteasomal protein catabolic process GO:0061136 87 1.000
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 6 0.999
regulation of chromosome segregation GO:0051983 44 0.999
regulation of mitosis GO:0007088 63 0.999
metaphase anaphase transition of cell cycle GO:0044784 21 0.998
chromosome separation GO:0051304 23 0.996
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.994
regulation of proteolysis GO:0030162 293 0.985
mitotic sister chromatid segregation GO:0000070 53 0.981
positive regulation of mitosis GO:0045840 25 0.981
regulation of cellular protein catabolic process GO:1903362 96 0.976
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.971
regulation of nuclear division GO:0051783 65 0.969
ubiquitin dependent protein catabolic process GO:0006511 206 0.967
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.965
sister chromatid segregation GO:0000819 54 0.964
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.962
regulation of cell division GO:0051302 116 0.959
modification dependent protein catabolic process GO:0019941 209 0.958
cellular macromolecule catabolic process GO:0044265 380 0.952
cellular protein catabolic process GO:0044257 261 0.951
mitotic cell cycle phase transition GO:0044772 162 0.948
chromosome segregation GO:0007059 114 0.939
positive regulation of chromosome segregation GO:0051984 9 0.924
regulation of mitotic cell cycle phase transition GO:1901990 118 0.913
mitotic nuclear division GO:0007067 119 0.899
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.896
organelle fission GO:0048285 149 0.895
negative regulation of mitotic sister chromatid separation GO:2000816 17 0.893
negative regulation of proteolysis GO:0045861 132 0.876
regulation of mitotic sister chromatid segregation GO:0033047 27 0.859
mitotic cell cycle process GO:1903047 286 0.856
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.838
modification dependent macromolecule catabolic process GO:0043632 212 0.830
regulation of chromosome organization GO:0033044 103 0.814
female gamete generation GO:0007292 2 0.809
protein catabolic process GO:0030163 325 0.799
positive regulation of protein catabolic process GO:0045732 75 0.783
cell division GO:0051301 168 0.782
positive regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051437 2 0.762
regulation of cell cycle process GO:0010564 266 0.762
oogenesis GO:0048477 2 0.754
microtubule polymerization GO:0046785 18 0.737
mitotic spindle assembly checkpoint GO:0007094 14 0.707
regulation of cell cycle phase transition GO:1901987 126 0.702
positive regulation of mitotic sister chromatid separation GO:1901970 6 0.657
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.653
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.648
activation of anaphase promoting complex activity GO:0051488 6 0.647
positive regulation of cellular protein catabolic process GO:1903364 37 0.645
centromeric sister chromatid cohesion GO:0070601 3 0.644
nuclear division GO:0000280 128 0.609
negative regulation of mitotic cell cycle GO:0045930 102 0.605
positive regulation of cell division GO:0051781 59 0.592
positive regulation of organelle organization GO:0010638 195 0.591
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.586
regulation of protein ubiquitination GO:0031396 95 0.586
mitotic cell cycle GO:0000278 326 0.530
positive regulation of ubiquitin protein transferase activity GO:0051443 18 0.507
mitotic spindle checkpoint GO:0071174 18 0.500
negative regulation of mitotic anaphase promoting complex activity GO:0060564 4 0.467
regulation of mitotic cell cycle GO:0007346 189 0.464
regulation of protein processing GO:0070613 150 0.455
negative regulation of protein maturation GO:1903318 142 0.449
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.426
positive regulation of cell cycle GO:0045787 140 0.423
regulation of cell cycle GO:0051726 393 0.422
positive regulation of cellular catabolic process GO:0031331 284 0.415
regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051439 6 0.405
positive regulation of protein ubiquitination GO:0031398 53 0.402
activation of mitotic anaphase promoting complex activity GO:0007092 2 0.399
cyclin catabolic process GO:0008054 6 0.358
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.358
spindle checkpoint GO:0031577 26 0.357
positive regulation of chromosome organization GO:2001252 41 0.356
negative regulation of chromosome segregation GO:0051985 18 0.356
positive regulation of nuclear division GO:0051785 27 0.305
spindle assembly checkpoint GO:0071173 17 0.285
positive regulation of mitotic metaphase anaphase transition GO:0045842 6 0.282
positive regulation of proteolysis GO:0045862 142 0.278
regulation of dna dependent dna replication initiation GO:0030174 3 0.263
negative regulation of cell cycle process GO:0010948 121 0.245
negative regulation of protein processing GO:0010955 142 0.245
negative regulation of organelle organization GO:0010639 126 0.241
regulation of protein maturation GO:1903317 150 0.239
cell cycle phase transition GO:0044770 173 0.235
regulation of protein catabolic process GO:0042176 155 0.229
central nervous system myelination GO:0022010 1 0.212
negative regulation of meiotic cell cycle GO:0051447 2 0.209
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.179
dna replication initiation GO:0006270 6 0.164
proteasomal protein catabolic process GO:0010498 176 0.161
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.160
cellular response to dna damage stimulus GO:0006974 379 0.153
dna conformation change GO:0071103 113 0.146
meiotic nuclear division GO:0007126 10 0.139
regulation of dna metabolic process GO:0051052 153 0.131
microtubule cytoskeleton organization GO:0000226 176 0.125
regulation of cellular ketone metabolic process GO:0010565 50 0.123
negative regulation of sister chromatid segregation GO:0033046 17 0.121
positive regulation of cell cycle process GO:0090068 106 0.117
protein polymerization GO:0051258 71 0.116
positive regulation of mitotic cell cycle GO:0045931 60 0.116
meiosis i GO:0007127 4 0.116
sensory organ development GO:0007423 52 0.110
negative regulation of catalytic activity GO:0043086 335 0.103
negative regulation of protein metabolic process GO:0051248 391 0.103
cardiac muscle tissue development GO:0048738 39 0.101
positive regulation of catabolic process GO:0009896 310 0.100
negative regulation of dendritic spine development GO:0061000 1 0.099
negative regulation of ubiquitin protein transferase activity GO:0051444 8 0.097
negative regulation of cellular protein catabolic process GO:1903363 38 0.092
regulation of synaptic transmission GO:0050804 11 0.091
negative regulation of transferase activity GO:0051348 124 0.090
negative regulation of protein phosphorylation GO:0001933 140 0.086
organelle assembly GO:0070925 176 0.086
negative regulation of chromosome organization GO:2001251 48 0.085
dna replication GO:0006260 116 0.084
maintenance of location GO:0051235 112 0.082
mrna 3 end processing GO:0031124 24 0.082
nervous system development GO:0007399 293 0.082
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 17 0.078
positive regulation of mitotic cell cycle phase transition GO:1901992 19 0.073
oocyte development GO:0048599 1 0.073
reproductive system development GO:0061458 56 0.072
Worm
negative regulation of cellular catabolic process GO:0031330 83 0.070
embryo development GO:0009790 123 0.065
Worm
cellular amine metabolic process GO:0044106 41 0.064
gonad development GO:0008406 34 0.064
Worm
regulation of cytoskeleton organization GO:0051493 177 0.064
negative regulation of programmed cell death GO:0043069 321 0.062
negative regulation of axonogenesis GO:0050771 4 0.061
oocyte differentiation GO:0009994 2 0.061
negative regulation of cell cycle GO:0045786 193 0.061
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.060
negative regulation of developmental process GO:0051093 247 0.060
rna processing GO:0006396 255 0.059
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.056
anterior posterior axis specification GO:0009948 2 0.056
Worm
organophosphate catabolic process GO:0046434 430 0.055
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.054
negative regulation of protein modification process GO:0031400 200 0.054
regulation of meiotic cell cycle GO:0051445 4 0.050
cell development GO:0048468 328 0.049
negative regulation of dna metabolic process GO:0051053 57 0.049
negative regulation of mitosis GO:0045839 24 0.048
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.047
cytokinesis GO:0000910 96 0.047
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.047
regulation of transferase activity GO:0051338 355 0.046
cytoskeleton dependent cytokinesis GO:0061640 22 0.045
cellular ketone metabolic process GO:0042180 80 0.044
compound eye development GO:0048749 1 0.042
negative regulation of cellular protein metabolic process GO:0032269 353 0.042
negative regulation of excitatory postsynaptic membrane potential GO:0090394 1 0.042
regulation of cell activation GO:0050865 125 0.041
covalent chromatin modification GO:0016569 254 0.039
positive regulation of cellular component organization GO:0051130 376 0.038
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.036
developmental process involved in reproduction GO:0003006 66 0.035
Worm
negative regulation of cellular component organization GO:0051129 235 0.035
post embryonic development GO:0009791 2 0.034
negative regulation of mitotic sister chromatid segregation GO:0033048 17 0.034
regulation of leukocyte activation GO:0002694 115 0.034
histone modification GO:0016570 251 0.034
long term synaptic potentiation GO:0060291 1 0.033
leukocyte activation involved in immune response GO:0002366 30 0.033
immune response GO:0006955 307 0.032
regulation of lymphocyte activation GO:0051249 103 0.032
circulatory system development GO:0072359 262 0.032
regulation of cell cell adhesion mediated by cadherin GO:2000047 4 0.031
phospholipid dephosphorylation GO:0046839 10 0.031
negative regulation of cell death GO:0060548 345 0.030
spindle organization GO:0007051 53 0.030
single organism reproductive process GO:0044702 98 0.030
Worm
cellular amino acid metabolic process GO:0006520 116 0.030
nuclear transport GO:0051169 179 0.030
inositol phosphate dephosphorylation GO:0046855 4 0.030
regulation of cellular amine metabolic process GO:0033238 11 0.030
mitotic cytokinesis GO:0000281 19 0.030
cell cycle checkpoint GO:0000075 117 0.030
secondary metabolic process GO:0019748 17 0.028
regulation of histone modification GO:0031056 47 0.028
protein localization to organelle GO:0033365 280 0.027
amine metabolic process GO:0009308 44 0.027
lymphocyte activation GO:0046649 133 0.027
single organism carbohydrate metabolic process GO:0044723 193 0.027
negative regulation of apoptotic process GO:0043066 316 0.027
negative regulation of cell motility GO:2000146 104 0.026
generation of neurons GO:0048699 152 0.026
axon regeneration GO:0031103 1 0.025
positive regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000060 3 0.025
chromatin organization GO:0006325 351 0.025
regulation of cellular amino acid metabolic process GO:0006521 6 0.025
regulation of ubiquitin protein transferase activity GO:0051438 28 0.024
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051436 4 0.024
negative regulation of hydrolase activity GO:0051346 182 0.024
central nervous system neuron axonogenesis GO:0021955 3 0.023
regulation of meiosis GO:0040020 3 0.023
positive regulation of cellular amine metabolic process GO:0033240 7 0.023
dendrite development GO:0016358 24 0.023
microtubule based process GO:0007017 210 0.023
regulation of cell cycle checkpoint GO:1901976 21 0.023
regulation of dendrite development GO:0050773 18 0.022
carbohydrate derivative biosynthetic process GO:1901137 207 0.022
maintenance of protein location in cell GO:0032507 56 0.022
negative regulation of dna replication GO:0008156 29 0.022
purine ribonucleoside metabolic process GO:0046128 437 0.022
regulation of protein serine threonine kinase activity GO:0071900 179 0.022
negative regulation of phosphate metabolic process GO:0045936 267 0.021
regulation of apoptotic signaling pathway GO:2001233 175 0.021
regulation of dna replication GO:0006275 68 0.021
receptor metabolic process GO:0043112 81 0.021
positive regulation of cell proliferation GO:0008284 301 0.021
neurogenesis GO:0022008 169 0.021
negative regulation of catabolic process GO:0009895 104 0.021
negative regulation of kinase activity GO:0033673 106 0.021
microtubule anchoring GO:0034453 24 0.020
apoptotic signaling pathway GO:0097190 268 0.020
presynaptic membrane organization GO:0097090 3 0.020
cellular carbohydrate metabolic process GO:0044262 84 0.019
regulation of intracellular transport GO:0032386 195 0.019
endothelial cell migration GO:0043542 86 0.019
embryo development ending in birth or egg hatching GO:0009792 34 0.019
Worm
negative regulation of cell differentiation GO:0045596 171 0.019
mitotic metaphase plate congression GO:0007080 14 0.019
protein alkylation GO:0008213 74 0.018
dendritic spine organization GO:0097061 4 0.018
protein glycosylation GO:0006486 62 0.018
cellular protein complex assembly GO:0043623 188 0.018
myeloid leukocyte activation GO:0002274 34 0.017
methylation GO:0032259 106 0.017
macromolecule glycosylation GO:0043413 63 0.017
negative regulation of dendrite development GO:2000171 5 0.017
canonical wnt signaling pathway GO:0060070 116 0.017
regulation of mrna processing GO:0050684 48 0.017
anatomical structure formation involved in morphogenesis GO:0048646 284 0.017
response to abiotic stimulus GO:0009628 336 0.017
neuron differentiation GO:0030182 138 0.017
single organism cellular localization GO:1902580 332 0.017
regulation of protein localization GO:0032880 296 0.017
g1 s transition of mitotic cell cycle GO:0000082 78 0.016
regulation of protein kinase activity GO:0045859 289 0.016
meiotic cell cycle checkpoint GO:0033313 1 0.016
negative regulation of protein ubiquitination GO:0031397 35 0.016
nucleoside catabolic process GO:0009164 408 0.016
cell projection organization GO:0030030 252 0.016
actin filament organization GO:0007015 128 0.016
positive regulation of phosphorylation GO:0042327 394 0.016
protein acylation GO:0043543 138 0.016
spindle assembly GO:0051225 29 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
eye development GO:0001654 42 0.015
vesicle mediated transport GO:0016192 371 0.015
determination of adult lifespan GO:0008340 2 0.015
ribonucleoside catabolic process GO:0042454 406 0.015
purine containing compound biosynthetic process GO:0072522 88 0.015
positive regulation of transferase activity GO:0051347 227 0.015
purine nucleoside catabolic process GO:0006152 398 0.014
negative regulation of phosphorus metabolic process GO:0010563 267 0.014
cilium assembly GO:0042384 63 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
negative regulation of phosphorylation GO:0042326 174 0.014
meiotic cell cycle process GO:1903046 8 0.014
negative regulation of cell cycle phase transition GO:1901988 89 0.014
positive regulation of intracellular protein transport GO:0090316 76 0.014
response to calcium ion GO:0051592 46 0.013
mrna metabolic process GO:0016071 175 0.013
mitotic cell cycle checkpoint GO:0007093 68 0.013
epithelial cell migration GO:0010631 119 0.013
purine ribonucleotide catabolic process GO:0009154 404 0.013
negative regulation of synaptic transmission GO:0050805 2 0.013
cardiovascular system development GO:0072358 262 0.013
innate immune response GO:0045087 178 0.013
regulation of cellular component biogenesis GO:0044087 281 0.013
regulation of vesicle mediated transport GO:0060627 130 0.013
dna repair GO:0006281 198 0.013
regulation of dna dependent dna replication GO:0090329 19 0.013
establishment of meiotic spindle localization GO:0051295 2 0.013
multicellular organismal response to stress GO:0033555 1 0.013
regulation of response to external stimulus GO:0032101 222 0.013
regulation of cellular response to stress GO:0080135 244 0.012
reproduction GO:0000003 63 0.012
Worm
regulation of nucleocytoplasmic transport GO:0046822 98 0.012
chemotaxis GO:0006935 157 0.012
male meiosis GO:0007140 1 0.012
genitalia development GO:0048806 10 0.012
Worm
negative regulation of locomotion GO:0040013 118 0.012
epithelium migration GO:0090132 119 0.012
sexual reproduction GO:0019953 37 0.012
morphogenesis of a polarized epithelium GO:0001738 3 0.012
transmission of nerve impulse GO:0019226 11 0.012
phagocytosis GO:0006909 42 0.012
regulation of neurogenesis GO:0050767 82 0.012
cytokine production GO:0001816 247 0.012
regulation of lymphocyte mediated immunity GO:0002706 33 0.012
head development GO:0060322 108 0.012
somatic recombination of immunoglobulin gene segments GO:0016447 4 0.012
nucleotide excision repair dna incision GO:0033683 7 0.012
convergent extension GO:0060026 1 0.012
establishment of organelle localization GO:0051656 59 0.011
positive regulation of secretion GO:0051047 116 0.011
regulation of phosphatase activity GO:0010921 81 0.011
development of primary sexual characteristics GO:0045137 35 0.011
Worm
hematopoietic or lymphoid organ development GO:0048534 186 0.011
regulation of cell migration GO:0030334 289 0.011
protein maturation GO:0051604 233 0.011
regulation of t cell activation GO:0050863 77 0.011
positive regulation of cell cycle phase transition GO:1901989 22 0.011
regulation of immunoglobulin production GO:0002637 4 0.011
rostrocaudal neural tube patterning GO:0021903 1 0.011
negative regulation of dna dependent dna replication GO:2000104 9 0.011
negative regulation of cellular component movement GO:0051271 106 0.011
phosphatidylinositol dephosphorylation GO:0046856 7 0.011
intrinsic apoptotic signaling pathway GO:0097193 127 0.011
cellular lipid metabolic process GO:0044255 303 0.011
regulation of homeostatic process GO:0032844 121 0.011
microtubule organizing center organization GO:0031023 62 0.011
carbohydrate metabolic process GO:0005975 207 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.011
oocyte maturation GO:0001556 1 0.010
regulation of cell morphogenesis GO:0022604 153 0.010
neural tube patterning GO:0021532 2 0.010
glycerophospholipid metabolic process GO:0006650 84 0.010
negative regulation of cell division GO:0051782 31 0.010
regulation of ligase activity GO:0051340 29 0.010
neuroblast proliferation GO:0007405 4 0.010
cell cycle g1 s phase transition GO:0044843 80 0.010
rna phosphodiester bond hydrolysis GO:0090501 35 0.010
maintenance of location in cell GO:0051651 62 0.010
protein kinase b signaling GO:0043491 69 0.010
hemopoiesis GO:0030097 180 0.010
stem cell differentiation GO:0048863 93 0.010
positive regulation of protein phosphorylation GO:0001934 313 0.010

ANAPC4 disease predictions

Disease DO term ID Size Probability Func Analog Org
gastrointestinal system cancer DOID:3119 52 0.048
cancer DOID:162 167 0.048
disease of cellular proliferation DOID:14566 174 0.048
organ system cancer DOID:0050686 164 0.048
sensory system disease DOID:0050155 203 0.026
nervous system disease DOID:863 431 0.026
eye and adnexa disease DOID:1492 150 0.019
eye disease DOID:5614 149 0.019
central nervous system disease DOID:331 186 0.014
neurodegenerative disease DOID:1289 102 0.014
endocrine gland cancer DOID:170 26 0.013
male reproductive organ cancer DOID:3856 16 0.013
reproductive organ cancer DOID:193 23 0.013