Homo sapiens

15 known processes

APEH

N-acylaminoacyl-peptide hydrolase

(Aliases: D3S48E,OPH,D3F15S2,APH,DNF15S2,MGC2178,ACPH)

APEH biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cofactor metabolic process GO:0051186 87 0.406
cellular amino acid metabolic process GO:0006520 116 0.149
determination of adult lifespan GO:0008340 2 0.148
post embryonic development GO:0009791 2 0.134
coenzyme metabolic process GO:0006732 65 0.111
cellular protein complex assembly GO:0043623 188 0.077
cellular macromolecular complex assembly GO:0034622 324 0.074
oxidation reduction process GO:0055114 396 0.072
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.071
purine ribonucleoside metabolic process GO:0046128 437 0.069
protein oligomerization GO:0051259 173 0.067
ribonucleotide catabolic process GO:0009261 405 0.059
cellular ketone metabolic process GO:0042180 80 0.059
glycosyl compound catabolic process GO:1901658 413 0.059
multicellular organismal aging GO:0010259 3 0.056
regulation of cellular amino acid metabolic process GO:0006521 6 0.055
female gamete generation GO:0007292 2 0.055
purine nucleoside triphosphate metabolic process GO:0009144 412 0.053
purine containing compound biosynthetic process GO:0072522 88 0.052
regulation of cellular amine metabolic process GO:0033238 11 0.051
purine nucleotide catabolic process GO:0006195 405 0.049
ribonucleoside catabolic process GO:0042454 406 0.048
cellular modified amino acid metabolic process GO:0006575 64 0.048
nucleoside phosphate catabolic process GO:1901292 412 0.047
organophosphate catabolic process GO:0046434 430 0.045
ribonucleoside triphosphate catabolic process GO:0009203 391 0.044
regulation of cellular ketone metabolic process GO:0010565 50 0.043
ribonucleoside monophosphate metabolic process GO:0009161 187 0.042
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.041
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.041
purine nucleoside triphosphate catabolic process GO:0009146 392 0.040
carbohydrate metabolic process GO:0005975 207 0.040
nucleotide biosynthetic process GO:0009165 109 0.039
cytoplasmic transport GO:0016482 379 0.039
lipid localization GO:0010876 106 0.039
maintenance of location GO:0051235 112 0.038
purine nucleoside monophosphate metabolic process GO:0009126 186 0.038
cellular amine metabolic process GO:0044106 41 0.037
response to cytokine GO:0034097 232 0.036
positive regulation of cellular component organization GO:0051130 376 0.036
nucleoside catabolic process GO:0009164 408 0.036
positive regulation of cellular amine metabolic process GO:0033240 7 0.036
positive regulation of developmental process GO:0051094 314 0.035
response to oxygen containing compound GO:1901700 369 0.035
internal protein amino acid acetylation GO:0006475 101 0.035
atp metabolic process GO:0046034 176 0.034
nucleoside triphosphate metabolic process GO:0009141 422 0.033
oogenesis GO:0048477 2 0.033
alpha amino acid catabolic process GO:1901606 26 0.033
amine metabolic process GO:0009308 44 0.033
regulation of proteolysis GO:0030162 293 0.032
ribonucleoside triphosphate metabolic process GO:0009199 412 0.031
purine ribonucleoside catabolic process GO:0046130 398 0.031
purine containing compound catabolic process GO:0072523 411 0.030
cellular protein catabolic process GO:0044257 261 0.030
ribose phosphate biosynthetic process GO:0046390 82 0.030
nucleoside monophosphate metabolic process GO:0009123 191 0.030
response to abiotic stimulus GO:0009628 336 0.030
regulation of nucleoside metabolic process GO:0009118 209 0.029
purine ribonucleotide catabolic process GO:0009154 404 0.029
multi organism cellular process GO:0044764 156 0.029
carbohydrate derivative biosynthetic process GO:1901137 207 0.027
transmembrane transport GO:0055085 399 0.027
protein homooligomerization GO:0051260 100 0.027
response to organonitrogen compound GO:0010243 156 0.027
nucleotide catabolic process GO:0009166 408 0.027
positive regulation of proteolysis GO:0045862 142 0.027
organophosphate biosynthetic process GO:0090407 163 0.026
fatty acid metabolic process GO:0006631 115 0.026
small gtpase mediated signal transduction GO:0007264 78 0.026
nuclear transport GO:0051169 179 0.026
nucleoside triphosphate catabolic process GO:0009143 394 0.025
actin filament based process GO:0030029 224 0.025
dephosphorylation GO:0016311 209 0.025
protein modification by small protein conjugation GO:0032446 342 0.024
monocarboxylic acid metabolic process GO:0032787 185 0.024
positive regulation of apoptotic process GO:0043065 246 0.024
intracellular protein transport GO:0006886 270 0.024
ras protein signal transduction GO:0007265 73 0.024
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.023
cell division GO:0051301 168 0.023
cellular response to cytokine stimulus GO:0071345 181 0.022
positive regulation of hydrolase activity GO:0051345 331 0.022
microtubule based process GO:0007017 210 0.022
single organism cellular localization GO:1902580 332 0.022
protein acetylation GO:0006473 116 0.022
small molecule catabolic process GO:0044282 92 0.022
positive regulation of organelle organization GO:0010638 195 0.022
protein tetramerization GO:0051262 47 0.021
protein catabolic process GO:0030163 325 0.021
adult locomotory behavior GO:0008344 1 0.021
guanosine containing compound catabolic process GO:1901069 239 0.021
regulation of cell differentiation GO:0045595 393 0.020
dicarboxylic acid metabolic process GO:0043648 29 0.020
negative regulation of catalytic activity GO:0043086 335 0.020
protein polymerization GO:0051258 71 0.020
negative regulation of cellular protein metabolic process GO:0032269 353 0.020
interspecies interaction between organisms GO:0044419 156 0.020
cellular component morphogenesis GO:0032989 314 0.020
cellular lipid metabolic process GO:0044255 303 0.020
cellular response to dna damage stimulus GO:0006974 379 0.019
microtubule cytoskeleton organization GO:0000226 176 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
actin cytoskeleton organization GO:0030036 207 0.019
organonitrogen compound biosynthetic process GO:1901566 200 0.019
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.019
negative regulation of protein metabolic process GO:0051248 391 0.019
posttranscriptional regulation of gene expression GO:0010608 213 0.019
cellular macromolecule catabolic process GO:0044265 380 0.019
protein localization to organelle GO:0033365 280 0.019
viral life cycle GO:0019058 132 0.018
mapk cascade GO:0000165 288 0.018
organelle assembly GO:0070925 176 0.018
cell morphogenesis GO:0000902 296 0.018
regulation of mapk cascade GO:0043408 262 0.017
system process GO:0003008 349 0.017
actin filament organization GO:0007015 128 0.017
histone modification GO:0016570 251 0.017
regulation of purine nucleotide catabolic process GO:0033121 205 0.017
purine ribonucleoside biosynthetic process GO:0046129 23 0.017
establishment of protein localization to organelle GO:0072594 172 0.017
vesicle mediated transport GO:0016192 371 0.017
protein processing GO:0016485 226 0.017
regulation of purine nucleotide metabolic process GO:1900542 264 0.017
negative regulation of developmental process GO:0051093 247 0.017
mitochondrion organization GO:0007005 156 0.017
defense response GO:0006952 315 0.016
regulation of protein complex assembly GO:0043254 147 0.016
regulation of peptidase activity GO:0052547 180 0.016
regulation of nucleotide metabolic process GO:0006140 269 0.016
gtp metabolic process GO:0046039 239 0.016
regulation of anatomical structure morphogenesis GO:0022603 286 0.016
secretion GO:0046903 254 0.016
cellular response to lipid GO:0071396 127 0.016
positive regulation of phosphorylation GO:0042327 394 0.016
organic acid biosynthetic process GO:0016053 97 0.016
ion homeostasis GO:0050801 230 0.015
locomotory behavior GO:0007626 1 0.015
negative regulation of cell proliferation GO:0008285 228 0.015
cell growth GO:0016049 160 0.015
regulation of endopeptidase activity GO:0052548 170 0.015
single organism reproductive process GO:0044702 98 0.015
positive regulation of catabolic process GO:0009896 310 0.015
single organism carbohydrate metabolic process GO:0044723 193 0.015
negative regulation of multicellular organismal process GO:0051241 317 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
response to biotic stimulus GO:0009607 276 0.015
negative regulation of cellular component organization GO:0051129 235 0.015
sulfur compound metabolic process GO:0006790 101 0.015
cytokine production GO:0001816 247 0.015
regulation of cell growth GO:0001558 135 0.015
protein autophosphorylation GO:0046777 123 0.015
positive regulation of immune system process GO:0002684 283 0.015
response to lipid GO:0033993 206 0.015
anatomical structure formation involved in morphogenesis GO:0048646 284 0.015
inorganic cation transmembrane transport GO:0098662 194 0.014
nucleocytoplasmic transport GO:0006913 176 0.014
guanosine containing compound metabolic process GO:1901068 244 0.014
positive regulation of protein phosphorylation GO:0001934 313 0.014
cellular response to oxygen containing compound GO:1901701 276 0.014
immune response GO:0006955 307 0.014
positive regulation of cell death GO:0010942 263 0.014
cell projection organization GO:0030030 252 0.014
negative regulation of phosphate metabolic process GO:0045936 267 0.014
growth GO:0040007 202 0.014
negative regulation of phosphorus metabolic process GO:0010563 267 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
chemical homeostasis GO:0048878 306 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
nucleoside phosphate biosynthetic process GO:1901293 109 0.014
vitamin metabolic process GO:0006766 26 0.014
protein acylation GO:0043543 138 0.014
regulation of cell cycle process GO:0010564 266 0.014
cytokinesis GO:0000910 96 0.014
regulation of cell motility GO:2000145 299 0.013
mitotic cell cycle GO:0000278 326 0.013
response to axon injury GO:0048678 1 0.013
negative regulation of programmed cell death GO:0043069 321 0.013
regulation of cellular response to stress GO:0080135 244 0.013
single organism membrane organization GO:0044802 268 0.013
ion transmembrane transport GO:0034220 338 0.013
covalent chromatin modification GO:0016569 254 0.013
cellular amino acid catabolic process GO:0009063 31 0.013
protein import GO:0017038 130 0.013
biological adhesion GO:0022610 331 0.013
epithelial cell differentiation GO:0030855 141 0.013
inorganic ion transmembrane transport GO:0098660 231 0.013
regulation of immune response GO:0050776 201 0.013
regulation of cellular component biogenesis GO:0044087 281 0.013
protein modification by small protein removal GO:0070646 92 0.013
cell adhesion GO:0007155 325 0.013
peptidyl tyrosine phosphorylation GO:0018108 170 0.013
regeneration GO:0031099 4 0.013
regulation of nucleotide catabolic process GO:0030811 205 0.013
mitochondrial respiratory chain complex i biogenesis GO:0097031 16 0.013
innate immune response GO:0045087 178 0.013
positive regulation of cell differentiation GO:0045597 211 0.013
alpha amino acid metabolic process GO:1901605 72 0.013
regulation of cell cycle GO:0051726 393 0.013
protein maturation GO:0051604 233 0.013
protein localization to membrane GO:0072657 160 0.012
regulation of transferase activity GO:0051338 355 0.012
gtp catabolic process GO:0006184 237 0.012
metal ion transport GO:0030001 272 0.012
membrane organization GO:0061024 292 0.012
purine nucleoside monophosphate catabolic process GO:0009128 158 0.012
lipid metabolic process GO:0006629 381 0.012
regulation of cysteine type endopeptidase activity GO:2000116 127 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
secretion by cell GO:0032940 226 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.012
regulation of kinase activity GO:0043549 314 0.012
regulation of growth GO:0040008 165 0.012
nucleoside monophosphate catabolic process GO:0009125 159 0.012
positive regulation of cellular component biogenesis GO:0044089 158 0.011
protein homotetramerization GO:0051289 28 0.011
regulation of mitochondrion organization GO:0010821 54 0.011
purine nucleoside catabolic process GO:0006152 398 0.011
activation of immune response GO:0002253 114 0.011
viral release from host cell GO:0019076 21 0.011
regulation of lipid metabolic process GO:0019216 96 0.011
response to other organism GO:0051707 261 0.011
small molecule biosynthetic process GO:0044283 157 0.011
regulation of actin cytoskeleton organization GO:0032956 116 0.011
oxidoreduction coenzyme metabolic process GO:0006733 19 0.011
negative regulation of transport GO:0051051 176 0.011
positive regulation of cell motility GO:2000147 177 0.011
negative regulation of protein modification process GO:0031400 200 0.011
neuromuscular junction development GO:0007528 3 0.011
epithelium development GO:0060429 227 0.011
endocytosis GO:0006897 159 0.011
positive regulation of programmed cell death GO:0043068 249 0.011
segmentation GO:0035282 4 0.011
protein targeting GO:0006605 187 0.011
blastoderm segmentation GO:0007350 2 0.011
myosin filament assembly GO:0031034 2 0.011
cation transmembrane transport GO:0098655 238 0.011
cellular ion homeostasis GO:0006873 168 0.011
negative regulation of cell cycle GO:0045786 193 0.011
cell projection morphogenesis GO:0048858 129 0.011
positive regulation of cytoskeleton organization GO:0051495 83 0.011
negative regulation of organelle organization GO:0010639 126 0.011
chromatin modification GO:0016568 298 0.011
nitrogen compound transport GO:0071705 191 0.011
regulation of secretion GO:0051046 194 0.011
embryo development GO:0009790 123 0.011
aging GO:0007568 66 0.010
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.010
positive regulation of cellular catabolic process GO:0031331 284 0.010
reproductive process GO:0022414 106 0.010
cation transport GO:0006812 331 0.010
spermatid differentiation GO:0048515 4 0.010
organic acid catabolic process GO:0016054 71 0.010
positive regulation of protein catabolic process GO:0045732 75 0.010
apoptotic signaling pathway GO:0097190 268 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.010
response to hormone GO:0009725 175 0.010
response to nitrogen compound GO:1901698 184 0.010
negative regulation of growth GO:0045926 97 0.010

APEH disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.190
amino acid metabolic disorder DOID:9252 50 0.190
inherited metabolic disorder DOID:655 242 0.190
immune system disease DOID:2914 155 0.031
central nervous system disease DOID:331 186 0.014
nervous system disease DOID:863 431 0.014
hematopoietic system disease DOID:74 100 0.011