Homo sapiens

29 known processes

APH1A

anterior pharynx defective 1 homolog A (C. elegans)

(Aliases: CGI-78,APH-1A,APH-1,6530402N02Rik)

APH1A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
notch receptor processing GO:0007220 2 0.981
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000059 3 0.839
membrane protein proteolysis GO:0033619 38 0.834
membrane protein ectodomain proteolysis GO:0006509 33 0.741
protein processing GO:0016485 226 0.622
protein maturation GO:0051604 233 0.440
amine metabolic process GO:0009308 44 0.392
hair follicle maturation GO:0048820 3 0.367
mononuclear cell proliferation GO:0032943 71 0.359
epithelial cell proliferation GO:0050673 128 0.326
copper ion import GO:0015677 1 0.325
amyloid precursor protein catabolic process GO:0042987 12 0.292
peptide metabolic process GO:0006518 51 0.266
synaptic vesicle exocytosis GO:0016079 3 0.247
post embryonic development GO:0009791 2 0.238
ion transmembrane transport GO:0034220 338 0.200
cerebral cortex cell migration GO:0021795 3 0.187
t cell activation GO:0042110 99 0.181
inorganic ion transmembrane transport GO:0098660 231 0.171
cell activation GO:0001775 213 0.163
protein glycosylation GO:0006486 62 0.161
cellular amino acid metabolic process GO:0006520 116 0.160
negative regulation of cellular amine metabolic process GO:0033239 3 0.157
lymphocyte proliferation GO:0046651 70 0.155
beta amyloid metabolic process GO:0050435 12 0.155
neurotransmitter secretion GO:0007269 4 0.148
positive regulation of immune system process GO:0002684 283 0.144
lymphocyte activation GO:0046649 133 0.143
amino acid transport GO:0006865 28 0.143
leukocyte activation GO:0045321 164 0.137
cation transmembrane transport GO:0098655 238 0.128
t cell proliferation GO:0042098 45 0.121
thymus development GO:0048538 3 0.118
regulation of cellular amino acid metabolic process GO:0006521 6 0.118
protein localization to organelle GO:0033365 280 0.116
regulation of cellular amine metabolic process GO:0033238 11 0.109
transmembrane transport GO:0055085 399 0.107
melanocyte differentiation GO:0030318 2 0.106
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000058 7 0.104
hair cycle phase GO:0044851 3 0.104
amyloid precursor protein metabolic process GO:0042982 17 0.102
negative regulation of axonogenesis GO:0050771 4 0.100
cellular amine metabolic process GO:0044106 41 0.100
protein modification by small protein conjugation GO:0032446 342 0.096
cellular ketone metabolic process GO:0042180 80 0.093
vacuole organization GO:0007033 44 0.093
myeloid cell homeostasis GO:0002262 34 0.089
calcium ion transport GO:0006816 147 0.085
ion homeostasis GO:0050801 230 0.084
mapk cascade GO:0000165 288 0.081
macromolecule glycosylation GO:0043413 63 0.080
cellular amide metabolic process GO:0043603 69 0.079
macroautophagy GO:0016236 39 0.076
cellular chemical homeostasis GO:0055082 180 0.074
memory GO:0007613 3 0.070
cation transport GO:0006812 331 0.070
cardiac muscle cell contraction GO:0086003 4 0.070
leukocyte proliferation GO:0070661 74 0.068
protein ubiquitination GO:0016567 314 0.068
proteasomal protein catabolic process GO:0010498 176 0.067
inorganic cation transmembrane transport GO:0098662 194 0.065
cellular homeostasis GO:0019725 196 0.063
cerebral cortex neuron differentiation GO:0021895 1 0.063
negative regulation of protein metabolic process GO:0051248 391 0.062
carboxylic acid transport GO:0046942 63 0.061
multicellular organismal aging GO:0010259 3 0.058
glycosylation GO:0070085 71 0.058
beta amyloid formation GO:0034205 7 0.057
cellular macromolecule catabolic process GO:0044265 380 0.057
glycoprotein biosynthetic process GO:0009101 91 0.056
positive regulation of coagulation GO:0050820 11 0.056
anion transport GO:0006820 161 0.054
regulation of cellular ketone metabolic process GO:0010565 50 0.053
secretion GO:0046903 254 0.053
nucleoside triphosphate catabolic process GO:0009143 394 0.051
negative regulation of phosphate metabolic process GO:0045936 267 0.051
brain morphogenesis GO:0048854 1 0.050
determination of adult lifespan GO:0008340 2 0.048
nervous system development GO:0007399 293 0.048
organelle assembly GO:0070925 176 0.047
positive regulation of transferase activity GO:0051347 227 0.047
actin mediated cell contraction GO:0070252 12 0.046
transition metal ion transport GO:0000041 23 0.045
ubiquitin dependent protein catabolic process GO:0006511 206 0.045
cellular divalent inorganic cation homeostasis GO:0072503 128 0.045
carbohydrate derivative biosynthetic process GO:1901137 207 0.043
regulation of transferase activity GO:0051338 355 0.043
organic acid transport GO:0015849 65 0.043
immune effector process GO:0002252 159 0.043
regulation of immune response GO:0050776 201 0.042
regulation of cell differentiation GO:0045595 393 0.042
motor neuron axon guidance GO:0008045 2 0.041
positive regulation of transport GO:0051050 336 0.041
regulation of cell cycle process GO:0010564 266 0.041
immune response GO:0006955 307 0.040
mitotic cell cycle GO:0000278 326 0.040
regulation of cell cycle GO:0051726 393 0.040
locomotory behavior GO:0007626 1 0.040
glycoprotein metabolic process GO:0009100 110 0.040
positive regulation of immune response GO:0050778 159 0.040
hematopoietic progenitor cell differentiation GO:0002244 38 0.039
purine nucleoside triphosphate catabolic process GO:0009146 392 0.039
negative regulation of catalytic activity GO:0043086 335 0.039
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.039
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.039
cellular ion homeostasis GO:0006873 168 0.039
signal transduction by phosphorylation GO:0023014 297 0.039
hemopoiesis GO:0030097 180 0.039
actin filament based process GO:0030029 224 0.038
positive regulation of protein phosphorylation GO:0001934 313 0.038
secretion by cell GO:0032940 226 0.038
circulatory system development GO:0072359 262 0.038
cellular response to external stimulus GO:0071496 111 0.038
regulation of binding GO:0051098 111 0.037
chemical homeostasis GO:0048878 306 0.037
purine containing compound catabolic process GO:0072523 411 0.037
mating GO:0007618 1 0.036
oxidation reduction process GO:0055114 396 0.035
autophagy GO:0006914 88 0.035
negative regulation of developmental process GO:0051093 247 0.035
segmentation GO:0035282 4 0.035
single organism cellular localization GO:1902580 332 0.034
regulation of protein catabolic process GO:0042176 155 0.034
modification dependent macromolecule catabolic process GO:0043632 212 0.034
associative learning GO:0008306 1 0.034
negative regulation of transferase activity GO:0051348 124 0.034
cilium organization GO:0044782 68 0.033
regulation of intracellular transport GO:0032386 195 0.033
positive regulation of protein kinase activity GO:0045860 190 0.033
regulation of cardiac muscle contraction GO:0055117 33 0.033
regulation of protein processing GO:0070613 150 0.033
divalent inorganic cation transport GO:0072511 158 0.032
negative regulation of phosphorus metabolic process GO:0010563 267 0.032
ribonucleoside catabolic process GO:0042454 406 0.032
regulation of synaptic plasticity GO:0048167 3 0.032
cation homeostasis GO:0055080 189 0.032
protein targeting GO:0006605 187 0.031
wnt signaling pathway GO:0016055 156 0.031
endoplasmic reticulum calcium ion homeostasis GO:0032469 9 0.031
negative regulation of protein processing GO:0010955 142 0.031
cellular response to dna damage stimulus GO:0006974 379 0.031
defense response GO:0006952 315 0.030
negative regulation of phosphorylation GO:0042326 174 0.030
immune response activating signal transduction GO:0002757 90 0.030
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.030
cytoplasmic transport GO:0016482 379 0.030
blood vessel development GO:0001568 172 0.030
regulation of protein maturation GO:1903317 150 0.030
positive regulation of secretion by cell GO:1903532 108 0.030
adult locomotory behavior GO:0008344 1 0.029
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.029
epithelial cell differentiation GO:0030855 141 0.029
negative regulation of protein maturation GO:1903318 142 0.029
negative regulation of cell death GO:0060548 345 0.029
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.029
negative regulation of programmed cell death GO:0043069 321 0.028
positive regulation of kinase activity GO:0033674 204 0.028
pituitary gland development GO:0021983 2 0.028
positive regulation of secretion GO:0051047 116 0.028
negative regulation of ubiquitin protein transferase activity GO:0051444 8 0.028
desmosome assembly GO:0002159 4 0.028
homeostasis of number of cells GO:0048872 40 0.028
negative regulation of proteolysis GO:0045861 132 0.028
negative regulation of catabolic process GO:0009895 104 0.027
exocytosis GO:0006887 71 0.027
regulation of kinase activity GO:0043549 314 0.027
cellular lipid metabolic process GO:0044255 303 0.027
ribonucleoside triphosphate metabolic process GO:0009199 412 0.027
negative regulation of cellular protein metabolic process GO:0032269 353 0.027
regulation of coagulation GO:0050818 44 0.027
positive regulation of programmed cell death GO:0043068 249 0.027
heart morphogenesis GO:0003007 48 0.027
small gtpase mediated signal transduction GO:0007264 78 0.027
cell adhesion GO:0007155 325 0.027
enzyme linked receptor protein signaling pathway GO:0007167 303 0.027
mitotic cell cycle phase transition GO:0044772 162 0.027
cell cell signaling GO:0007267 155 0.027
organelle localization GO:0051640 84 0.027
positive regulation of hydrolase activity GO:0051345 331 0.026
positive regulation of cellular component organization GO:0051130 376 0.026
cell projection organization GO:0030030 252 0.026
regulation of protein localization GO:0032880 296 0.026
ras protein signal transduction GO:0007265 73 0.026
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.026
negative regulation of ligase activity GO:0051352 8 0.026
positive regulation of apoptotic process GO:0043065 246 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
purine ribonucleoside metabolic process GO:0046128 437 0.026
negative regulation of protein catabolic process GO:0042177 59 0.026
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.026
cellular calcium ion homeostasis GO:0006874 117 0.025
neural tube patterning GO:0021532 2 0.025
regulation of protein serine threonine kinase activity GO:0071900 179 0.025
cellular cation homeostasis GO:0030003 163 0.025
somatic stem cell maintenance GO:0035019 4 0.025
blood circulation GO:0008015 113 0.025
positive regulation of developmental process GO:0051094 314 0.025
mitotic nuclear division GO:0007067 119 0.025
positive regulation of cellular amine metabolic process GO:0033240 7 0.025
regulation of neuron differentiation GO:0045664 70 0.025
negative regulation of protein phosphorylation GO:0001933 140 0.025
regulation of proteasomal protein catabolic process GO:0061136 87 0.024
immune system development GO:0002520 195 0.024
regulation of ras protein signal transduction GO:0046578 155 0.024
positive regulation of exocytosis GO:0045921 35 0.024
regulation of protein transport GO:0051223 213 0.024
biological adhesion GO:0022610 331 0.024
posttranscriptional regulation of gene expression GO:0010608 213 0.024
positive regulation of catabolic process GO:0009896 310 0.024
mitotic cell cycle process GO:1903047 286 0.024
carbohydrate metabolic process GO:0005975 207 0.024
protein catabolic process GO:0030163 325 0.024
embryonic heart tube morphogenesis GO:0003143 8 0.024
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.023
organophosphate catabolic process GO:0046434 430 0.023
gastrulation with mouth forming second GO:0001702 1 0.023
establishment of protein localization to organelle GO:0072594 172 0.023
protein stabilization GO:0050821 64 0.023
single organism carbohydrate metabolic process GO:0044723 193 0.023
anatomical structure maturation GO:0071695 9 0.023
cell cycle phase transition GO:0044770 173 0.023
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.023
activation of protein kinase activity GO:0032147 90 0.023
negative regulation of cellular protein catabolic process GO:1903363 38 0.023
lipid metabolic process GO:0006629 381 0.023
cellular response to starvation GO:0009267 58 0.023
positive regulation of cell death GO:0010942 263 0.023
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 20 0.022
negative regulation of multicellular organismal process GO:0051241 317 0.022
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.022
metal ion homeostasis GO:0055065 169 0.022
organelle fission GO:0048285 149 0.022
glycosyl compound catabolic process GO:1901658 413 0.022
nerve development GO:0021675 4 0.022
vesicle mediated transport GO:0016192 371 0.022
cellular response to oxygen containing compound GO:1901701 276 0.022
positive regulation of organelle organization GO:0010638 195 0.022
nucleotide catabolic process GO:0009166 408 0.022
modification dependent protein catabolic process GO:0019941 209 0.022
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.022
cell part morphogenesis GO:0032990 137 0.022
negative regulation of epidermal growth factor activated receptor activity GO:0007175 6 0.022
organic anion transport GO:0015711 103 0.021
negative regulation of apoptotic process GO:0043066 316 0.021
central nervous system development GO:0007417 123 0.021
compound eye development GO:0048749 1 0.021
immune response regulating signaling pathway GO:0002764 97 0.021
positive regulation of cellular catabolic process GO:0031331 284 0.021
regulation of endopeptidase activity GO:0052548 170 0.021
head development GO:0060322 108 0.021
regulation of protein kinase activity GO:0045859 289 0.021
regulation of receptor recycling GO:0001919 10 0.021
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.021
cell morphogenesis GO:0000902 296 0.020
cell projection assembly GO:0030031 126 0.020
purine ribonucleoside catabolic process GO:0046130 398 0.020
intracellular protein transport GO:0006886 270 0.020
neuroblast proliferation GO:0007405 4 0.020
negative regulation of cellular catabolic process GO:0031330 83 0.020
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.020
nitrogen compound transport GO:0071705 191 0.020
innate immune response GO:0045087 178 0.020
maintenance of location in cell GO:0051651 62 0.020
regulation of protein complex assembly GO:0043254 147 0.020
metal ion transport GO:0030001 272 0.019
regulation of protein ubiquitination GO:0031396 95 0.019
regulation of peptidase activity GO:0052547 180 0.019
female gamete generation GO:0007292 2 0.019
neuron development GO:0048666 113 0.019
cellular component morphogenesis GO:0032989 314 0.019
peripheral nervous system development GO:0007422 2 0.019
organic hydroxy compound metabolic process GO:1901615 147 0.019
establishment of organelle localization GO:0051656 59 0.019
neural tube formation GO:0001841 3 0.018
positive regulation of cytoskeleton organization GO:0051495 83 0.018
neuromuscular junction development GO:0007528 3 0.018
negative regulation of cell morphogenesis involved in differentiation GO:0010771 24 0.018
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.018
leukocyte activation involved in immune response GO:0002366 30 0.018
cellular protein catabolic process GO:0044257 261 0.018
cell fate determination GO:0001709 3 0.018
hair cycle GO:0042633 28 0.018
negative regulation of cellular component organization GO:0051129 235 0.018
salivary gland morphogenesis GO:0007435 4 0.018
positive regulation of mapk cascade GO:0043410 190 0.018
ribonucleotide catabolic process GO:0009261 405 0.018
single organism membrane organization GO:0044802 268 0.018
oogenesis GO:0048477 2 0.018
ribonucleoside triphosphate catabolic process GO:0009203 391 0.018
muscle system process GO:0003012 81 0.018
gtp metabolic process GO:0046039 239 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.018
hindlimb morphogenesis GO:0035137 2 0.018
regulation of neuroblast proliferation GO:1902692 3 0.018
positive regulation of cellular protein catabolic process GO:1903364 37 0.018
anatomical structure formation involved in morphogenesis GO:0048646 284 0.018
synaptic vesicle recycling GO:0036465 3 0.018
canonical wnt signaling pathway GO:0060070 116 0.018
regulation of glial cell differentiation GO:0045685 3 0.017
membrane organization GO:0061024 292 0.017
epithelial tube morphogenesis GO:0060562 38 0.017
neurological system process GO:0050877 163 0.017
regulation of nucleoside metabolic process GO:0009118 209 0.017
response to oxidative stress GO:0006979 121 0.017
reactive oxygen species metabolic process GO:0072593 75 0.017
divalent inorganic cation homeostasis GO:0072507 136 0.017
rna processing GO:0006396 255 0.017
oocyte differentiation GO:0009994 2 0.017
spermatid differentiation GO:0048515 4 0.017
regulation of endothelial cell differentiation GO:0045601 4 0.017
calcium ion transmembrane transport GO:0070588 76 0.017
heart process GO:0003015 62 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.017
nucleoside catabolic process GO:0009164 408 0.017
cell projection morphogenesis GO:0048858 129 0.017
regulation of neural precursor cell proliferation GO:2000177 4 0.017
positive regulation of map kinase activity GO:0043406 80 0.017
negative regulation of cell differentiation GO:0045596 171 0.017
limbic system development GO:0021761 3 0.017
regulation of stem cell differentiation GO:2000736 56 0.017
regulation of purine nucleotide metabolic process GO:1900542 264 0.017
regulation of anatomical structure morphogenesis GO:0022603 286 0.017
protein localization to membrane GO:0072657 160 0.016
cell morphogenesis involved in differentiation GO:0000904 144 0.016
regulation of defense response GO:0031347 154 0.016
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.016
action potential GO:0001508 34 0.016
hematopoietic or lymphoid organ development GO:0048534 186 0.016
myeloid leukocyte differentiation GO:0002573 60 0.016
regulation of actin cytoskeleton organization GO:0032956 116 0.016
positive regulation of cell cycle GO:0045787 140 0.016
cytokine production GO:0001816 247 0.016
negative regulation of protein modification process GO:0031400 200 0.016
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.016
regulation of receptor activity GO:0010469 47 0.016
regulation of proteolysis GO:0030162 293 0.016
divalent metal ion transport GO:0070838 152 0.016
positive regulation of intracellular transport GO:0032388 104 0.016
embryonic epithelial tube formation GO:0001838 4 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
regulation of cytoskeleton organization GO:0051493 177 0.016
cellular response to extracellular stimulus GO:0031668 72 0.016
establishment of protein localization to membrane GO:0090150 121 0.016
behavioral response to ethanol GO:0048149 2 0.016
chromatin organization GO:0006325 351 0.016
regulation of lymphocyte activation GO:0051249 103 0.016
nucleoside triphosphate metabolic process GO:0009141 422 0.016
response to starvation GO:0042594 59 0.016
embryonic limb morphogenesis GO:0030326 9 0.015
positive regulation of apoptotic signaling pathway GO:2001235 70 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.015
autonomic nervous system development GO:0048483 1 0.015
protein localization to plasma membrane GO:0072659 93 0.015
activation of immune response GO:0002253 114 0.015
cell type specific apoptotic process GO:0097285 125 0.015
hematopoietic stem cell differentiation GO:0060218 4 0.015
peptidyl tyrosine phosphorylation GO:0018108 170 0.015
autophagic cell death GO:0048102 3 0.015
system process GO:0003008 349 0.015
skeletal system development GO:0001501 79 0.015
mrna metabolic process GO:0016071 175 0.015
response to nitrogen compound GO:1901698 184 0.015
chromatin modification GO:0016568 298 0.015
positive regulation of protein catabolic process GO:0045732 75 0.015
circulatory system process GO:0003013 113 0.015
regulation of cardioblast differentiation GO:0051890 4 0.015
vasculature development GO:0001944 181 0.015
mitochondrial transport GO:0006839 60 0.015
regulation of exocytosis GO:0017157 46 0.015
negative regulation of receptor activity GO:2000272 15 0.015
somitogenesis GO:0001756 2 0.015
sensory perception of pain GO:0019233 4 0.015
cardiac muscle cell action potential involved in contraction GO:0086002 21 0.014
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.014
regulation of nucleotide metabolic process GO:0006140 269 0.014
sequestering of metal ion GO:0051238 24 0.014
cellular response to organonitrogen compound GO:0071417 124 0.014
nuclear transport GO:0051169 179 0.014
positive regulation of cell motility GO:2000147 177 0.014
neuron differentiation GO:0030182 138 0.014
ectoderm development GO:0007398 3 0.014
apoptotic signaling pathway GO:0097190 268 0.014
protein import into nucleus GO:0006606 104 0.014
regulation of neurotransmitter levels GO:0001505 15 0.014
positive regulation of cell cycle process GO:0090068 106 0.014
regulation of organ formation GO:0003156 4 0.014
plasma membrane organization GO:0007009 115 0.014
single organism nuclear import GO:1902593 104 0.014
synaptic transmission GO:0007268 61 0.014
regulation of leukocyte activation GO:0002694 115 0.014
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.014
embryonic forelimb morphogenesis GO:0035115 4 0.014
covalent chromatin modification GO:0016569 254 0.014
cilium morphogenesis GO:0060271 75 0.014
morphogenesis of a polarized epithelium GO:0001738 3 0.014
antigen receptor mediated signaling pathway GO:0050851 38 0.014
response to extracellular stimulus GO:0009991 85 0.014
negative regulation of protein ubiquitination GO:0031397 35 0.014
lung associated mesenchyme development GO:0060484 1 0.014
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
regulation of establishment of protein localization GO:0070201 242 0.013
i kappab kinase nf kappab signaling GO:0007249 166 0.013
regulation of cell cycle phase transition GO:1901987 126 0.013
regulation of cell development GO:0060284 161 0.013
negative regulation of cell fate specification GO:0009996 3 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
regulation of intracellular protein transport GO:0033157 123 0.013
lymphangiogenesis GO:0001946 7 0.013
cardiovascular system development GO:0072358 262 0.013
positive regulation of protein transport GO:0051222 135 0.013
sequestering of calcium ion GO:0051208 17 0.013
positive regulation of cellular component movement GO:0051272 181 0.013
protein targeting to nucleus GO:0044744 104 0.013
regeneration GO:0031099 4 0.013
natural killer cell activation involved in immune response GO:0002323 2 0.013
regulation of cell projection organization GO:0031344 107 0.013
circadian behavior GO:0048512 2 0.013
anterior posterior axis specification GO:0009948 2 0.013
neurogenesis GO:0022008 169 0.013
negative regulation of protein kinase activity GO:0006469 98 0.013
myeloid leukocyte activation GO:0002274 34 0.013
cell development GO:0048468 328 0.013
regulation of neurotransmitter secretion GO:0046928 3 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
leukocyte differentiation GO:0002521 98 0.013
response to axon injury GO:0048678 1 0.013
negative regulation of peptidase activity GO:0010466 91 0.013
purine ribonucleotide catabolic process GO:0009154 404 0.013
activation of mapkk activity GO:0000186 18 0.013
carboxylic acid biosynthetic process GO:0046394 97 0.012
sex determination GO:0007530 3 0.012
regulation of cellular component movement GO:0051270 334 0.012
regulation of ion transport GO:0043269 189 0.012
cilium assembly GO:0042384 63 0.012
organ formation GO:0048645 3 0.012
regulation of map kinase activity GO:0043405 108 0.012
single organism cell adhesion GO:0098602 179 0.012
ceramide metabolic process GO:0006672 25 0.012
regulation of cell growth GO:0001558 135 0.012
protein import GO:0017038 130 0.012
endocytosis GO:0006897 159 0.012
regulation of actin filament based process GO:0032970 141 0.012
blood vessel morphogenesis GO:0048514 162 0.012
visual learning GO:0008542 1 0.012
extrinsic apoptotic signaling pathway GO:0097191 119 0.012
regulation of microtubule based process GO:0032886 74 0.012
cellular response to endogenous stimulus GO:0071495 336 0.012
positive regulation of gliogenesis GO:0014015 4 0.012
embryonic appendage morphogenesis GO:0035113 9 0.012
regulation of locomotion GO:0040012 329 0.012
negative regulation of gliogenesis GO:0014014 3 0.012
positive regulation of lymphocyte activation GO:0051251 73 0.012
response to organic cyclic compound GO:0014070 204 0.012
organophosphate biosynthetic process GO:0090407 163 0.012
neural tube development GO:0021915 9 0.012
receptor metabolic process GO:0043112 81 0.012
lipid biosynthetic process GO:0008610 177 0.012
patterning of blood vessels GO:0001569 2 0.012
primary neural tube formation GO:0014020 3 0.012
dephosphorylation GO:0016311 209 0.012
positive regulation of mesenchymal cell proliferation GO:0002053 2 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.012
purine nucleoside triphosphate metabolic process GO:0009144 412 0.012

APH1A disease predictions

Disease DO term ID Size Probability Func Analog Org
skin disease DOID:37 33 0.917
integumentary system disease DOID:16 43 0.917
muscular disease DOID:0080000 114 0.285
musculoskeletal system disease DOID:17 223 0.285
muscle tissue disease DOID:66 113 0.285
myopathy DOID:423 104 0.256
heart disease DOID:114 68 0.256
cardiomyopathy DOID:0050700 50 0.256
cardiovascular system disease DOID:1287 106 0.256
dilated cardiomyopathy DOID:12930 32 0.176
intrinsic cardiomyopathy DOID:0060036 50 0.176
disease of mental health DOID:150 70 0.148
cognitive disorder DOID:1561 29 0.148
central nervous system disease DOID:331 186 0.049
neurodegenerative disease DOID:1289 102 0.049
nervous system disease DOID:863 431 0.049
dementia DOID:1307 19 0.048
alzheimer s disease DOID:10652 16 0.048
tauopathy DOID:680 16 0.048
bone disease DOID:0080001 88 0.026
connective tissue disease DOID:65 109 0.026
bone development disease DOID:0080006 55 0.025
cancer DOID:162 167 0.024
disease of cellular proliferation DOID:14566 174 0.024
disease of metabolism DOID:0014667 295 0.019
organ system cancer DOID:0050686 164 0.018
sensory system disease DOID:0050155 203 0.015
eye and adnexa disease DOID:1492 150 0.015
eye disease DOID:5614 149 0.013