Homo sapiens

61 known processes

APLF

aprataxin and PNKP like factor

(Aliases: MGC47799,Xip1,FLJ16593,C2orf13,APFL,PALF)

APLF biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna ligation involved in dna repair GO:0051103 4 1.000
immunoglobulin v d j recombination GO:0033152 1 0.999
pro b cell differentiation GO:0002328 1 0.999
v d j recombination GO:0033151 3 0.995
dna ligation GO:0006266 10 0.990
single strand break repair GO:0000012 6 0.947
somatic stem cell maintenance GO:0035019 4 0.926
hematopoietic progenitor cell differentiation GO:0002244 38 0.874
dna recombination GO:0006310 77 0.858
double strand break repair GO:0006302 101 0.849
somatic diversification of immunoglobulins involved in immune response GO:0002208 3 0.839
isotype switching GO:0045190 3 0.822
nucleotide excision repair GO:0006289 31 0.713
non recombinational repair GO:0000726 14 0.697
fibroblast proliferation GO:0048144 33 0.630
somatic recombination of immunoglobulin gene segments GO:0016447 4 0.629
t cell differentiation in thymus GO:0033077 4 0.604
response to gamma radiation GO:0010332 14 0.560
positive regulation of cell differentiation GO:0045597 211 0.535
positive regulation of cell development GO:0010720 92 0.525
hematopoietic or lymphoid organ development GO:0048534 186 0.517
positive regulation of developmental process GO:0051094 314 0.509
positive regulation of fibroblast proliferation GO:0048146 21 0.443
leukocyte mediated immunity GO:0002443 59 0.435
replicative cell aging GO:0001302 3 0.430
immune effector process GO:0002252 159 0.405
immune response GO:0006955 307 0.401
t cell activation GO:0042110 99 0.391
dna damage response detection of dna damage GO:0042769 3 0.380
regulation of cell differentiation GO:0045595 393 0.369
double strand break repair via nonhomologous end joining GO:0006303 10 0.367
positive regulation of cell proliferation GO:0008284 301 0.367
lymphoid progenitor cell differentiation GO:0002320 3 0.364
lymphocyte mediated immunity GO:0002449 48 0.360
positive regulation of neurogenesis GO:0050769 49 0.360
immune system development GO:0002520 195 0.354
cell activation involved in immune response GO:0002263 30 0.351
lymphocyte activation GO:0046649 133 0.349
cell activation GO:0001775 213 0.338
stem cell differentiation GO:0048863 93 0.283
regulation of fibroblast proliferation GO:0048145 32 0.270
response to ionizing radiation GO:0010212 65 0.267
cell aging GO:0007569 52 0.264
b cell activation GO:0042113 33 0.261
regulation of neurogenesis GO:0050767 82 0.253
leukocyte activation involved in immune response GO:0002366 30 0.252
negative regulation of neuron apoptotic process GO:0043524 23 0.248
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 3 0.245
nervous system development GO:0007399 293 0.241
negative regulation of cell death GO:0060548 345 0.239
hemopoiesis GO:0030097 180 0.231
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.220
negative regulation of apoptotic process GO:0043066 316 0.219
somatic diversification of immune receptors GO:0002200 8 0.215
leukocyte activation GO:0045321 164 0.215
hematopoietic stem cell differentiation GO:0060218 4 0.212
stem cell maintenance GO:0019827 19 0.207
negative regulation of programmed cell death GO:0043069 321 0.197
regulation of nervous system development GO:0051960 88 0.194
response to abiotic stimulus GO:0009628 336 0.193
b cell mediated immunity GO:0019724 10 0.190
leukocyte differentiation GO:0002521 98 0.188
generation of neurons GO:0048699 152 0.184
response to radiation GO:0009314 151 0.177
immunoglobulin mediated immune response GO:0016064 10 0.169
cell type specific apoptotic process GO:0097285 125 0.166
negative regulation of developmental process GO:0051093 247 0.147
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 5 0.134
positive regulation of nervous system development GO:0051962 54 0.130
central nervous system development GO:0007417 123 0.126
production of molecular mediator of immune response GO:0002440 37 0.124
lymphocyte activation involved in immune response GO:0002285 20 0.123
regulation of neuron death GO:1901214 56 0.123
lymphocyte differentiation GO:0030098 35 0.122
response to oxygen containing compound GO:1901700 369 0.117
single organism carbohydrate metabolic process GO:0044723 193 0.116
regulation of neuron apoptotic process GO:0043523 35 0.114
t cell differentiation GO:0030217 29 0.114
glycoprotein metabolic process GO:0009100 110 0.110
somatic diversification of immunoglobulins GO:0016445 6 0.110
cellular response to dna damage stimulus GO:0006974 379 0.107
chromatin assembly or disassembly GO:0006333 78 0.106
negative regulation of cell differentiation GO:0045596 171 0.106
glycoprotein biosynthetic process GO:0009101 91 0.097
dna conformation change GO:0071103 113 0.097
protein glycosylation GO:0006486 62 0.093
adaptive immune response GO:0002250 49 0.091
dna repair GO:0006281 198 0.084
neuron death GO:0070997 65 0.083
carbohydrate derivative biosynthetic process GO:1901137 207 0.082
protein poly adp ribosylation GO:0070212 3 0.078
base excision repair GO:0006284 21 0.078
immunoglobulin production GO:0002377 12 0.076
negative regulation of neuron death GO:1901215 32 0.075
regulation of ligase activity GO:0051340 29 0.074
amine metabolic process GO:0009308 44 0.070
neuron apoptotic process GO:0051402 39 0.069
nucleoside triphosphate catabolic process GO:0009143 394 0.066
regulation of cell development GO:0060284 161 0.065
carbohydrate metabolic process GO:0005975 207 0.063
nucleoside catabolic process GO:0009164 408 0.063
macromolecule glycosylation GO:0043413 63 0.061
protein autoprocessing GO:0016540 4 0.060
purine nucleoside triphosphate catabolic process GO:0009146 392 0.058
dephosphorylation GO:0016311 209 0.058
stem cell development GO:0048864 69 0.057
chordate embryonic development GO:0043009 34 0.057
neurogenesis GO:0022008 169 0.056
nucleoside triphosphate metabolic process GO:0009141 422 0.055
cellular amine metabolic process GO:0044106 41 0.053
atp metabolic process GO:0046034 176 0.048
cell development GO:0048468 328 0.048
somatic cell dna recombination GO:0016444 6 0.045
glycosylation GO:0070085 71 0.044
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.043
cellular macromolecule catabolic process GO:0044265 380 0.042
regulation of dna metabolic process GO:0051052 153 0.042
cellular ketone metabolic process GO:0042180 80 0.041
nucleoside monophosphate catabolic process GO:0009125 159 0.040
post embryonic development GO:0009791 2 0.040
biological adhesion GO:0022610 331 0.040
purine containing compound catabolic process GO:0072523 411 0.039
glycosyl compound catabolic process GO:1901658 413 0.039
regulation of cellular amino acid metabolic process GO:0006521 6 0.038
purine nucleoside catabolic process GO:0006152 398 0.038
ribonucleotide catabolic process GO:0009261 405 0.038
regulation of cellular amine metabolic process GO:0033238 11 0.038
positive regulation of ligase activity GO:0051351 19 0.037
dna replication GO:0006260 116 0.036
regulation of growth rate GO:0040009 1 0.036
system process GO:0003008 349 0.036
oxidation reduction process GO:0055114 396 0.034
cellular amino acid metabolic process GO:0006520 116 0.033
response to oxidative stress GO:0006979 121 0.033
purine ribonucleotide catabolic process GO:0009154 404 0.032
organophosphate catabolic process GO:0046434 430 0.032
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.031
regulation of cellular ketone metabolic process GO:0010565 50 0.031
negative regulation of phosphorus metabolic process GO:0010563 267 0.030
response to reactive oxygen species GO:0000302 61 0.029
regulation of protein kinase activity GO:0045859 289 0.029
apoptotic signaling pathway GO:0097190 268 0.029
cellular response to oxidative stress GO:0034599 85 0.029
circulatory system development GO:0072359 262 0.029
regulation of kinase activity GO:0043549 314 0.028
nucleotide catabolic process GO:0009166 408 0.028
positive regulation of cellular component organization GO:0051130 376 0.027
telomere organization GO:0032200 33 0.027
positive regulation of cellular catabolic process GO:0031331 284 0.027
nucleoside monophosphate metabolic process GO:0009123 191 0.027
protein adp ribosylation GO:0006471 9 0.027
positive regulation of cellular amine metabolic process GO:0033240 7 0.026
single organism cellular localization GO:1902580 332 0.026
negative regulation of phosphate metabolic process GO:0045936 267 0.026
purine ribonucleoside metabolic process GO:0046128 437 0.026
hippocampus development GO:0021766 1 0.026
purine nucleotide catabolic process GO:0006195 405 0.026
cellular lipid metabolic process GO:0044255 303 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
positive regulation of cell death GO:0010942 263 0.025
response to growth factor GO:0070848 205 0.025
adult locomotory behavior GO:0008344 1 0.025
response to inorganic substance GO:0010035 127 0.025
atp catabolic process GO:0006200 157 0.025
ion transmembrane transport GO:0034220 338 0.025
lipid biosynthetic process GO:0008610 177 0.025
negative regulation of catalytic activity GO:0043086 335 0.024
determination of adult lifespan GO:0008340 2 0.024
mitochondrion organization GO:0007005 156 0.024
macromolecule methylation GO:0043414 97 0.024
purine nucleoside triphosphate metabolic process GO:0009144 412 0.024
lipid metabolic process GO:0006629 381 0.024
regulation of nucleotide metabolic process GO:0006140 269 0.023
metal ion transport GO:0030001 272 0.023
cellular response to growth factor stimulus GO:0071363 197 0.023
regulation of dna binding GO:0051101 37 0.023
ribonucleoside monophosphate metabolic process GO:0009161 187 0.023
covalent chromatin modification GO:0016569 254 0.023
dna dependent dna replication GO:0006261 44 0.023
cardiovascular system development GO:0072358 262 0.023
cation transport GO:0006812 331 0.023
viral life cycle GO:0019058 132 0.022
enzyme linked receptor protein signaling pathway GO:0007167 303 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.022
meiosis i GO:0007127 4 0.022
negative regulation of protein metabolic process GO:0051248 391 0.022
regulation of establishment of protein localization GO:0070201 242 0.022
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.021
cellular response to nitrogen compound GO:1901699 144 0.021
regulation of purine nucleotide catabolic process GO:0033121 205 0.021
regulation of purine nucleotide metabolic process GO:1900542 264 0.021
regeneration GO:0031099 4 0.021
cation transmembrane transport GO:0098655 238 0.021
positive regulation of nucleotide catabolic process GO:0030813 185 0.021
dna packaging GO:0006323 77 0.021
inorganic ion transmembrane transport GO:0098660 231 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.021
protein catabolic process GO:0030163 325 0.021
multi organism cellular process GO:0044764 156 0.020
positive regulation of catabolic process GO:0009896 310 0.020
single organism membrane organization GO:0044802 268 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.020
interspecies interaction between organisms GO:0044419 156 0.020
locomotory behavior GO:0007626 1 0.020
ribonucleoside catabolic process GO:0042454 406 0.020
actin filament based process GO:0030029 224 0.020
positive regulation of gtpase activity GO:0043547 166 0.020
regulation of nucleotide catabolic process GO:0030811 205 0.020
signal transduction by p53 class mediator GO:0072331 72 0.020
cellular response to oxygen containing compound GO:1901701 276 0.020
positive regulation of transport GO:0051050 336 0.020
negative regulation of cellular protein metabolic process GO:0032269 353 0.019
regulation of protein stability GO:0031647 87 0.019
regulation of cell cycle GO:0051726 393 0.019
positive regulation of apoptotic process GO:0043065 246 0.019
cardiac muscle cell contraction GO:0086003 4 0.019
embryo development GO:0009790 123 0.019
dna replication independent nucleosome organization GO:0034724 27 0.019
detection of stimulus GO:0051606 85 0.019
b cell activation involved in immune response GO:0002312 5 0.019
regulation of nucleoside metabolic process GO:0009118 209 0.018
purine ribonucleoside catabolic process GO:0046130 398 0.018
positive regulation of nucleotide metabolic process GO:0045981 230 0.018
ras protein signal transduction GO:0007265 73 0.018
vesicle mediated transport GO:0016192 371 0.018
positive regulation of immune response GO:0050778 159 0.018
positive regulation of immune system process GO:0002684 283 0.018
limbic system development GO:0021761 3 0.018
regulation of anatomical structure morphogenesis GO:0022603 286 0.018
chemical homeostasis GO:0048878 306 0.017
regulation of lymphocyte activation GO:0051249 103 0.017
nucleoside phosphate catabolic process GO:1901292 412 0.017
positive regulation of programmed cell death GO:0043068 249 0.017
ribonucleoside triphosphate metabolic process GO:0009199 412 0.017
regulation of cell cycle process GO:0010564 266 0.017
cellular component morphogenesis GO:0032989 314 0.017
regulation of cellular component movement GO:0051270 334 0.017
protein localization to organelle GO:0033365 280 0.017
protein localization to nucleus GO:0034504 136 0.017
modification dependent protein catabolic process GO:0019941 209 0.016
regulation of transferase activity GO:0051338 355 0.016
positive regulation of proteolysis GO:0045862 142 0.016
histone modification GO:0016570 251 0.016
rho protein signal transduction GO:0007266 26 0.016
nucleoside phosphate biosynthetic process GO:1901293 109 0.016
nucleotide biosynthetic process GO:0009165 109 0.016
cellular response to endogenous stimulus GO:0071495 336 0.016
actin filament based movement GO:0030048 17 0.016
neuromuscular junction development GO:0007528 3 0.016
positive regulation of protein transport GO:0051222 135 0.016
guanosine containing compound catabolic process GO:1901069 239 0.016
cellular response to organonitrogen compound GO:0071417 124 0.016
viral process GO:0016032 146 0.016
negative regulation of protein phosphorylation GO:0001933 140 0.016
regulation of cellular response to stress GO:0080135 244 0.016
response to hydrogen peroxide GO:0042542 40 0.016
positive regulation of hydrolase activity GO:0051345 331 0.016
intracellular receptor signaling pathway GO:0030522 104 0.016
metencephalon development GO:0022037 2 0.016
negative regulation of cell cycle GO:0045786 193 0.016
cell adhesion GO:0007155 325 0.016
negative regulation of protein modification process GO:0031400 200 0.016
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.016
striated muscle contraction GO:0006941 52 0.016
response to organonitrogen compound GO:0010243 156 0.015
regulation of cytoskeleton organization GO:0051493 177 0.015
response to transforming growth factor beta GO:0071559 94 0.015
compound eye development GO:0048749 1 0.015
inorganic cation transmembrane transport GO:0098662 194 0.015
regulation of glial cell differentiation GO:0045685 3 0.015
mitotic cell cycle process GO:1903047 286 0.015
nuclear transport GO:0051169 179 0.015
response to wounding GO:0009611 168 0.015
hindbrain development GO:0030902 3 0.015
response to decreased oxygen levels GO:0036293 96 0.015
cell morphogenesis GO:0000902 296 0.015
regulation of protein transport GO:0051223 213 0.015
chromatin modification GO:0016568 298 0.015
cellular response to reactive oxygen species GO:0034614 50 0.015
positive regulation of transferase activity GO:0051347 227 0.015
chemotaxis GO:0006935 157 0.015
regulation of cytokine production GO:0001817 232 0.015
mitotic cell cycle phase transition GO:0044772 162 0.015
secretion by cell GO:0032940 226 0.014
regulation of intracellular transport GO:0032386 195 0.014
transmembrane transport GO:0055085 399 0.014
regulation of immune response GO:0050776 201 0.014
divalent metal ion transport GO:0070838 152 0.014
cellular response to insulin stimulus GO:0032869 41 0.014
positive regulation of kinase activity GO:0033674 204 0.014
single stranded viral rna replication via double stranded dna intermediate GO:0039692 9 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.014
positive regulation of gtp catabolic process GO:0033126 166 0.014
cellular response to hormone stimulus GO:0032870 125 0.014
rna processing GO:0006396 255 0.014
regulation of protein localization to nucleus GO:1900180 85 0.014
response to hormone GO:0009725 175 0.014
positive regulation of protein kinase activity GO:0045860 190 0.014
cellular response to nutrient levels GO:0031669 69 0.014
cellular response to external stimulus GO:0071496 111 0.014
rab protein signal transduction GO:0032482 4 0.014
single organism cell adhesion GO:0098602 179 0.014
membrane organization GO:0061024 292 0.014
organonitrogen compound biosynthetic process GO:1901566 200 0.014
nuclear import GO:0051170 106 0.014
regulation of cytoplasmic transport GO:1903649 149 0.014
organic acid biosynthetic process GO:0016053 97 0.014
protein localization to membrane GO:0072657 160 0.014
mating GO:0007618 1 0.013
regulation of protein serine threonine kinase activity GO:0071900 179 0.013
negative regulation of dna metabolic process GO:0051053 57 0.013
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.013
nitrogen compound transport GO:0071705 191 0.013
positive regulation of phosphorylation GO:0042327 394 0.013
protein targeting GO:0006605 187 0.013
calcium ion transport GO:0006816 147 0.013
response to other organism GO:0051707 261 0.013
regulation of secretion GO:0051046 194 0.013
cellular response to peptide hormone stimulus GO:0071375 56 0.013
positive regulation of intracellular protein transport GO:0090316 76 0.013
cytoplasmic transport GO:0016482 379 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
purine nucleotide biosynthetic process GO:0006164 84 0.013
growth GO:0040007 202 0.013
regulation of cell adhesion GO:0030155 166 0.013
regulation of actin filament based process GO:0032970 141 0.013
divalent inorganic cation transport GO:0072511 158 0.013
response to peptide GO:1901652 65 0.013
negative regulation of immune system process GO:0002683 136 0.013
receptor metabolic process GO:0043112 81 0.013
positive regulation of cell cycle GO:0045787 140 0.013
cell cell signaling GO:0007267 155 0.013
protein maturation GO:0051604 233 0.013
regulation of secretion by cell GO:1903530 177 0.013
regulation of nucleocytoplasmic transport GO:0046822 98 0.013
generation of precursor metabolites and energy GO:0006091 68 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
cell part morphogenesis GO:0032990 137 0.013
neurological system process GO:0050877 163 0.013
aging GO:0007568 66 0.013
regulation of response to dna damage stimulus GO:2001020 94 0.013
i kappab kinase nf kappab signaling GO:0007249 166 0.012
defense response GO:0006952 315 0.012
wnt signaling pathway GO:0016055 156 0.012
negative regulation of transport GO:0051051 176 0.012
regulation of protein targeting GO:1903533 91 0.012
reciprocal dna recombination GO:0035825 4 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.012
negative regulation of multicellular organismal process GO:0051241 317 0.012
regulation of cell growth GO:0001558 135 0.012
sequestering of metal ion GO:0051238 24 0.012
positive regulation of mapk cascade GO:0043410 190 0.012
pharynx development GO:0060465 1 0.012
neuroblast proliferation GO:0007405 4 0.012
cell projection morphogenesis GO:0048858 129 0.012
protein ubiquitination GO:0016567 314 0.012
peptidyl tyrosine modification GO:0018212 170 0.012
chromatin organization GO:0006325 351 0.012
regulation of t cell activation GO:0050863 77 0.012
histone lysine methylation GO:0034968 50 0.012
innate immune response GO:0045087 178 0.012
cellular response to extracellular stimulus GO:0031668 72 0.012
purine ribonucleotide biosynthetic process GO:0009152 79 0.012
positive regulation of ras gtpase activity GO:0032320 117 0.012
cellular response to oxygen radical GO:0071450 6 0.012
circulatory system process GO:0003013 113 0.012
cellular response to ionizing radiation GO:0071479 32 0.012
regulation of response to external stimulus GO:0032101 222 0.012
telomere maintenance GO:0000723 32 0.012
gtp catabolic process GO:0006184 237 0.012
negative regulation of cellular component organization GO:0051129 235 0.012
positive regulation of cytoplasmic transport GO:1903651 82 0.012
leukocyte migration GO:0050900 107 0.012
negative regulation of transferase activity GO:0051348 124 0.012
regulation of ras protein signal transduction GO:0046578 155 0.012
regulation of gtpase activity GO:0043087 180 0.012
positive regulation of synaptic transmission GO:0050806 4 0.012
cell projection organization GO:0030030 252 0.012
activation of immune response GO:0002253 114 0.012
anatomical structure homeostasis GO:0060249 100 0.012
regulation of vasculature development GO:1901342 97 0.012
segmentation GO:0035282 4 0.012
phospholipid metabolic process GO:0006644 99 0.011
reactive oxygen species metabolic process GO:0072593 75 0.011
monocarboxylic acid metabolic process GO:0032787 185 0.011
positive regulation of binding GO:0051099 45 0.011
blastoderm segmentation GO:0007350 2 0.011
intrinsic apoptotic signaling pathway GO:0097193 127 0.011
cofactor metabolic process GO:0051186 87 0.011
positive regulation of organelle organization GO:0010638 195 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
regulation of growth GO:0040008 165 0.011
rna interference GO:0016246 4 0.011
regulation of angiogenesis GO:0045765 92 0.011
rna splicing GO:0008380 131 0.011
regulation of cell morphogenesis GO:0022604 153 0.011
positive regulation of smad protein import into nucleus GO:0060391 8 0.011
guanosine containing compound metabolic process GO:1901068 244 0.011
protein processing GO:0016485 226 0.011
sensory perception of pain GO:0019233 4 0.011
establishment of protein localization to membrane GO:0090150 121 0.011
demethylation GO:0070988 37 0.011
intracellular protein transport GO:0006886 270 0.011
response to light stimulus GO:0009416 87 0.011
positive regulation of cellular component movement GO:0051272 181 0.011
response to drug GO:0042493 81 0.011
positive regulation of transcription regulatory region dna binding GO:2000679 8 0.011
negative regulation of protein kinase activity GO:0006469 98 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
regulation of gtp catabolic process GO:0033124 180 0.011
regulation of binding GO:0051098 111 0.011
signal transduction involved in regulation of gene expression GO:0023019 1 0.011
anion transport GO:0006820 161 0.011
ribose phosphate biosynthetic process GO:0046390 82 0.011
response to hypoxia GO:0001666 96 0.011
cell growth GO:0016049 160 0.011
positive regulation of cell migration GO:0030335 172 0.011
ribonucleoside monophosphate catabolic process GO:0009158 158 0.011
organophosphate biosynthetic process GO:0090407 163 0.011
neurotransmitter secretion GO:0007269 4 0.011
thymus development GO:0048538 3 0.011
dna catabolic process GO:0006308 49 0.011
regulation of protein localization GO:0032880 296 0.011
monovalent inorganic cation transport GO:0015672 128 0.011
microtubule cytoskeleton organization GO:0000226 176 0.011
cellular component disassembly GO:0022411 92 0.011
memory GO:0007613 3 0.010
regulation of dephosphorylation GO:0035303 96 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.010
mitotic nuclear division GO:0007067 119 0.010
positive regulation of cell motility GO:2000147 177 0.010
actin cytoskeleton organization GO:0030036 207 0.010
cellular response to radiation GO:0071478 65 0.010
regulation of multi organism process GO:0043900 157 0.010
response to peptide hormone GO:0043434 61 0.010
associative learning GO:0008306 1 0.010
myeloid cell differentiation GO:0030099 117 0.010
ribonucleotide biosynthetic process GO:0009260 81 0.010
heart development GO:0007507 95 0.010
regulation of viral process GO:0050792 103 0.010
positive regulation of secretion by cell GO:1903532 108 0.010
positive regulation of protein phosphorylation GO:0001934 313 0.010
dna geometric change GO:0032392 32 0.010
dna catabolic process exonucleolytic GO:0000738 17 0.010
muscle contraction GO:0006936 73 0.010
regulation of ras gtpase activity GO:0032318 128 0.010
lipid localization GO:0010876 106 0.010
negative regulation of intracellular signal transduction GO:1902532 183 0.010
cell projection assembly GO:0030031 126 0.010
endomembrane system organization GO:0010256 196 0.010
positive regulation of cell adhesion GO:0045785 84 0.010
regulation of hormone levels GO:0010817 125 0.010
response to lipid GO:0033993 206 0.010
peripheral nervous system development GO:0007422 2 0.010
reactive nitrogen species metabolic process GO:2001057 3 0.010
rhythmic behavior GO:0007622 2 0.010

APLF disease predictions

Disease DO term ID Size Probability Func Analog Org
primary immunodeficiency disease DOID:612 36 0.902
immune system disease DOID:2914 155 0.902
disease of cellular proliferation DOID:14566 174 0.480
combined t cell and b cell immunodeficiency DOID:628 12 0.402
cancer DOID:162 167 0.344
organ system cancer DOID:0050686 164 0.344
myeloma DOID:0070004 7 0.240
immune system cancer DOID:0060083 36 0.240
hematologic cancer DOID:2531 36 0.240
bone marrow cancer DOID:4960 10 0.240
epilepsy syndrome DOID:1826 41 0.080
central nervous system disease DOID:331 186 0.080
brain disease DOID:936 73 0.080
electroclinical syndrome DOID:0050701 32 0.080
neonatal period electroclinical syndrome DOID:0050702 19 0.080
nervous system disease DOID:863 431 0.080
disease of metabolism DOID:0014667 295 0.029
sensory system disease DOID:0050155 203 0.021
inherited metabolic disorder DOID:655 242 0.019
eye and adnexa disease DOID:1492 150 0.017
eye disease DOID:5614 149 0.017
idiopathic generalized epilepsy DOID:1827 21 0.016
retinal disease DOID:5679 118 0.016
neurodegenerative disease DOID:1289 102 0.011
amino acid metabolic disorder DOID:9252 50 0.011
musculoskeletal system disease DOID:17 223 0.011