Homo sapiens

3 known processes

APPL2

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

(Aliases: DIP13B,FLJ10659)

APPL2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleoside phosphate catabolic process GO:1901292 412 0.781
gtp metabolic process GO:0046039 239 0.625
plasma membrane organization GO:0007009 115 0.604
Human
purine nucleoside triphosphate catabolic process GO:0009146 392 0.576
purine nucleoside triphosphate metabolic process GO:0009144 412 0.561
protein localization to plasma membrane GO:0072659 93 0.505
Human
organophosphate catabolic process GO:0046434 430 0.504
receptor metabolic process GO:0043112 81 0.493
nucleoside triphosphate metabolic process GO:0009141 422 0.468
cytoplasmic transport GO:0016482 379 0.467
guanosine containing compound metabolic process GO:1901068 244 0.464
nucleotide catabolic process GO:0009166 408 0.461
ribonucleoside triphosphate catabolic process GO:0009203 391 0.457
receptor internalization GO:0031623 43 0.448
gtp catabolic process GO:0006184 237 0.448
ribonucleoside triphosphate metabolic process GO:0009199 412 0.435
purine nucleoside catabolic process GO:0006152 398 0.432
nucleoside triphosphate catabolic process GO:0009143 394 0.414
exocytosis GO:0006887 71 0.407
purine ribonucleoside metabolic process GO:0046128 437 0.406
establishment of protein localization to membrane GO:0090150 121 0.395
Human
endosome organization GO:0007032 20 0.373
membrane organization GO:0061024 292 0.342
Human
endomembrane system organization GO:0010256 196 0.342
Human
single organism membrane organization GO:0044802 268 0.330
Human
regulation of cellular component size GO:0032535 82 0.295
cellular response to endogenous stimulus GO:0071495 336 0.294
nucleoside catabolic process GO:0009164 408 0.277
purine ribonucleoside catabolic process GO:0046130 398 0.260
cellular response to nitrogen compound GO:1901699 144 0.247
glycosyl compound catabolic process GO:1901658 413 0.245
vesicle mediated transport GO:0016192 371 0.238
regulation of synaptic vesicle transport GO:1902803 3 0.229
guanosine containing compound catabolic process GO:1901069 239 0.225
cellular response to hormone stimulus GO:0032870 125 0.210
purine containing compound catabolic process GO:0072523 411 0.204
single organism cellular localization GO:1902580 332 0.188
Human
response to hormone GO:0009725 175 0.186
regulation of anatomical structure size GO:0090066 101 0.185
ribonucleotide catabolic process GO:0009261 405 0.184
determination of adult lifespan GO:0008340 2 0.158
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.156
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.156
regulation of protein localization to plasma membrane GO:1903076 40 0.150
Human
cellular amino acid metabolic process GO:0006520 116 0.149
endocytosis GO:0006897 159 0.145
regulation of cellular amino acid metabolic process GO:0006521 6 0.141
plasma membrane to endosome transport GO:0048227 6 0.139
protein localization to membrane GO:0072657 160 0.138
Human
phagosome maturation GO:0090382 9 0.128
canonical wnt signaling pathway GO:0060070 116 0.122
ribonucleoside catabolic process GO:0042454 406 0.122
response to nitrogen compound GO:1901698 184 0.115
post golgi vesicle mediated transport GO:0006892 36 0.115
purine ribonucleotide catabolic process GO:0009154 404 0.113
nervous system development GO:0007399 293 0.109
synaptic vesicle exocytosis GO:0016079 3 0.106
intracellular protein transport GO:0006886 270 0.104
purine nucleotide catabolic process GO:0006195 405 0.102
multicellular organismal aging GO:0010259 3 0.101
mitotic cell cycle GO:0000278 326 0.079
secretion GO:0046903 254 0.078
regulation of protein kinase activity GO:0045859 289 0.077
regulation of intracellular transport GO:0032386 195 0.068
regulation of neurotransmitter secretion GO:0046928 3 0.068
carbohydrate transport GO:0008643 37 0.067
Human
golgi to plasma membrane transport GO:0006893 21 0.066
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.064
golgi to plasma membrane protein transport GO:0043001 19 0.063
receptor internalization involved in canonical wnt signaling pathway GO:2000286 3 0.063
negative regulation of cellular amine metabolic process GO:0033239 3 0.062
response to oxygen containing compound GO:1901700 369 0.059
positive regulation of intracellular transport GO:0032388 104 0.058
regulation of cell motility GO:2000145 299 0.057
regulation of establishment of protein localization GO:0070201 242 0.057
Human
actin cytoskeleton organization GO:0030036 207 0.055
post embryonic development GO:0009791 2 0.054
regulation of locomotion GO:0040012 329 0.053
cell projection organization GO:0030030 252 0.053
neurotransmitter secretion GO:0007269 4 0.052
generation of neurons GO:0048699 152 0.051
peptidyl serine phosphorylation GO:0018105 101 0.051
negative regulation of phosphorus metabolic process GO:0010563 267 0.051
cellular response to organonitrogen compound GO:0071417 124 0.051
regulation of synaptic vesicle exocytosis GO:2000300 2 0.050
positive regulation of cytoplasmic transport GO:1903651 82 0.050
neurogenesis GO:0022008 169 0.050
response to insulin GO:0032868 45 0.049
cellular response to oxygen containing compound GO:1901701 276 0.049
cell development GO:0048468 328 0.049
receptor mediated endocytosis GO:0006898 84 0.049
positive regulation of gtpase activity GO:0043547 166 0.048
regulation of cellular ketone metabolic process GO:0010565 50 0.047
cellular response to insulin stimulus GO:0032869 41 0.047
positive regulation of catabolic process GO:0009896 310 0.047
positive regulation of cell migration GO:0030335 172 0.047
actin filament based process GO:0030029 224 0.046
cellular component morphogenesis GO:0032989 314 0.045
segmentation GO:0035282 4 0.045
regulation of cell projection organization GO:0031344 107 0.045
rho protein signal transduction GO:0007266 26 0.045
regulation of mitotic cell cycle GO:0007346 189 0.045
negative regulation of catalytic activity GO:0043086 335 0.044
cellular amine metabolic process GO:0044106 41 0.044
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.044
maintenance of location GO:0051235 112 0.042
regulation of gtpase activity GO:0043087 180 0.042
mapk cascade GO:0000165 288 0.042
synaptic vesicle endocytosis GO:0048488 2 0.042
positive regulation of cell motility GO:2000147 177 0.042
protein catabolic process GO:0030163 325 0.041
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.041
regulation of cellular amine metabolic process GO:0033238 11 0.039
carbohydrate metabolic process GO:0005975 207 0.038
positive regulation of transport GO:0051050 336 0.037
regulation of cellular component movement GO:0051270 334 0.037
cellular response to peptide hormone stimulus GO:0071375 56 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
regulation of nucleotide metabolic process GO:0006140 269 0.036
positive regulation of transferase activity GO:0051347 227 0.036
regulation of exocytosis GO:0017157 46 0.036
regulation of cell cycle GO:0051726 393 0.036
organelle assembly GO:0070925 176 0.035
regulation of protein localization GO:0032880 296 0.035
Human
peptidyl serine modification GO:0018209 106 0.035
positive regulation of gtp catabolic process GO:0033126 166 0.035
regulation of purine nucleotide catabolic process GO:0033121 205 0.035
anatomical structure formation involved in morphogenesis GO:0048646 284 0.034
positive regulation of cellular amine metabolic process GO:0033240 7 0.034
positive regulation of cellular catabolic process GO:0031331 284 0.034
negative regulation of cell proliferation GO:0008285 228 0.034
endosomal vesicle fusion GO:0034058 1 0.034
regulation of synaptic plasticity GO:0048167 3 0.034
regulation of secretion by cell GO:1903530 177 0.034
negative regulation of phosphorylation GO:0042326 174 0.033
endosomal transport GO:0016197 129 0.033
positive regulation of early endosome to late endosome transport GO:2000643 3 0.032
adult locomotory behavior GO:0008344 1 0.032
monosaccharide transport GO:0015749 32 0.032
Human
cell part morphogenesis GO:0032990 137 0.032
negative regulation of developmental process GO:0051093 247 0.031
wnt signaling pathway GO:0016055 156 0.031
multivesicular body organization GO:0036257 2 0.031
regulation of transferase activity GO:0051338 355 0.031
regulation of purine nucleotide metabolic process GO:1900542 264 0.030
organelle fission GO:0048285 149 0.030
dephosphorylation GO:0016311 209 0.029
neuron projection development GO:0031175 106 0.029
positive regulation of kinase activity GO:0033674 204 0.029
memory GO:0007613 3 0.029
response to cytokine GO:0034097 232 0.029
amine metabolic process GO:0009308 44 0.029
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.029
mitotic cell cycle process GO:1903047 286 0.029
cellular component assembly involved in morphogenesis GO:0010927 73 0.029
response to peptide GO:1901652 65 0.028
cellular lipid metabolic process GO:0044255 303 0.028
cation transport GO:0006812 331 0.028
metal ion transport GO:0030001 272 0.028
glycoprotein biosynthetic process GO:0009101 91 0.027
positive regulation of cell differentiation GO:0045597 211 0.027
regulation of peptidyl serine phosphorylation GO:0033135 50 0.027
ras protein signal transduction GO:0007265 73 0.027
signal release GO:0023061 70 0.027
negative regulation of phosphate metabolic process GO:0045936 267 0.027
regulation of gtp catabolic process GO:0033124 180 0.027
regulation of cytoskeleton organization GO:0051493 177 0.027
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.027
ribonucleoside monophosphate catabolic process GO:0009158 158 0.026
histone modification GO:0016570 251 0.026
regulation of cell development GO:0060284 161 0.026
regulation of cytokine production GO:0001817 232 0.026
embryonic epithelial tube formation GO:0001838 4 0.026
positive regulation of cellular component movement GO:0051272 181 0.026
hexose transport GO:0008645 30 0.026
Human
morphogenesis of embryonic epithelium GO:0016331 4 0.025
cellular ketone metabolic process GO:0042180 80 0.025
cytokinesis GO:0000910 96 0.025
cellular macromolecular complex assembly GO:0034622 324 0.025
regulation of actin filament based process GO:0032970 141 0.025
negative regulation of cellular protein metabolic process GO:0032269 353 0.025
limbic system development GO:0021761 3 0.025
circulatory system development GO:0072359 262 0.025
cell division GO:0051301 168 0.025
carbohydrate derivative biosynthetic process GO:1901137 207 0.025
covalent chromatin modification GO:0016569 254 0.024
cell cycle phase transition GO:0044770 173 0.024
regulated secretory pathway GO:0045055 20 0.024
negative regulation of programmed cell death GO:0043069 321 0.024
organelle fusion GO:0048284 36 0.024
system process GO:0003008 349 0.024
regulation of ras protein signal transduction GO:0046578 155 0.024
signal transduction by phosphorylation GO:0023014 297 0.024
neurological system process GO:0050877 163 0.024
positive regulation of nucleotide metabolic process GO:0045981 230 0.024
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.024
lipid modification GO:0030258 84 0.023
regulation of kinase activity GO:0043549 314 0.023
regulation of ras gtpase activity GO:0032318 128 0.023
proteasomal protein catabolic process GO:0010498 176 0.023
behavioral response to ethanol GO:0048149 2 0.023
negative regulation of cell cycle phase transition GO:1901988 89 0.023
response to wounding GO:0009611 168 0.023
positive regulation of ras gtpase activity GO:0032320 117 0.022
oogenesis GO:0048477 2 0.022
organelle inheritance GO:0048308 2 0.022
nucleus localization GO:0051647 1 0.022
positive regulation of protein kinase activity GO:0045860 190 0.022
cell morphogenesis GO:0000902 296 0.022
anterior posterior axis specification GO:0009948 2 0.022
regulation of endocytosis GO:0030100 72 0.022
protein localization to organelle GO:0033365 280 0.022
chromatin modification GO:0016568 298 0.021
actin filament organization GO:0007015 128 0.021
multi organism cellular process GO:0044764 156 0.021
regulation of establishment of protein localization to plasma membrane GO:0090003 30 0.021
Human
positive regulation of cell proliferation GO:0008284 301 0.021
lipid metabolic process GO:0006629 381 0.021
positive regulation of cell death GO:0010942 263 0.021
vacuole organization GO:0007033 44 0.021
cell fate determination GO:0001709 3 0.021
wound healing GO:0042060 115 0.021
nuclear migration GO:0007097 1 0.021
response to peptide hormone GO:0043434 61 0.021
negative regulation of hydrolase activity GO:0051346 182 0.020
response to lipid GO:0033993 206 0.020
negative regulation of apoptotic process GO:0043066 316 0.020
regulation of rho protein signal transduction GO:0035023 79 0.020
glycerolipid metabolic process GO:0046486 107 0.020
regulation of cell migration GO:0030334 289 0.020
reactive oxygen species biosynthetic process GO:1903409 4 0.020
regulation of cytoplasmic transport GO:1903649 149 0.020
golgi vesicle transport GO:0048193 80 0.020
photoreceptor cell differentiation GO:0046530 2 0.020
organ formation GO:0048645 3 0.020
regulation of neuronal synaptic plasticity GO:0048168 1 0.020
single organism carbohydrate metabolic process GO:0044723 193 0.020
organ morphogenesis GO:0009887 147 0.020
phospholipid metabolic process GO:0006644 99 0.020
glycerophospholipid metabolic process GO:0006650 84 0.020
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.020
regulation of nucleoside metabolic process GO:0009118 209 0.020
negative regulation of cell cycle GO:0045786 193 0.020
cellular protein complex assembly GO:0043623 188 0.019
protein autophosphorylation GO:0046777 123 0.019
female gamete generation GO:0007292 2 0.019
modification dependent protein catabolic process GO:0019941 209 0.019
blastoderm segmentation GO:0007350 2 0.019
negative regulation of mitotic cell cycle GO:0045930 102 0.019
spermatid differentiation GO:0048515 4 0.019
negative regulation of protein metabolic process GO:0051248 391 0.019
negative regulation of cell cycle process GO:0010948 121 0.019
regulation of vesicle mediated transport GO:0060627 130 0.018
organelle localization GO:0051640 84 0.018
protein secretion GO:0009306 98 0.018
regulation of epithelial cell migration GO:0010632 93 0.018
neuroblast proliferation GO:0007405 4 0.018
reactive oxygen species metabolic process GO:0072593 75 0.018
positive regulation of cellular component organization GO:0051130 376 0.018
cell adhesion GO:0007155 325 0.018
regulation of autophagy GO:0010506 52 0.018
glycoprotein metabolic process GO:0009100 110 0.018
tissue regeneration GO:0042246 3 0.018
neural tube formation GO:0001841 3 0.018
cell projection morphogenesis GO:0048858 129 0.018
motor neuron axon guidance GO:0008045 2 0.018
cell growth GO:0016049 160 0.018
associative learning GO:0008306 1 0.018
cilium organization GO:0044782 68 0.018
spermatid development GO:0007286 4 0.018
single organism membrane fusion GO:0044801 37 0.018
regulation of cellular response to stress GO:0080135 244 0.018
macromolecule methylation GO:0043414 97 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.017
negative regulation of protein modification process GO:0031400 200 0.017
cellular response to growth factor stimulus GO:0071363 197 0.017
positive regulation of locomotion GO:0040017 186 0.017
rna interference GO:0016246 4 0.017
positive regulation of protein phosphorylation GO:0001934 313 0.017
cellular homeostasis GO:0019725 196 0.017
nuclear transport GO:0051169 179 0.017
meiotic chromosome segregation GO:0045132 4 0.017
epithelial cell migration GO:0010631 119 0.017
regulation of anatomical structure morphogenesis GO:0022603 286 0.017
neuromuscular junction development GO:0007528 3 0.017
interspecies interaction between organisms GO:0044419 156 0.017
negative regulation of cell death GO:0060548 345 0.017
positive regulation of immune system process GO:0002684 283 0.017
regulation of axon extension involved in axon guidance GO:0048841 2 0.017
neural tube closure GO:0001843 3 0.017
epithelium migration GO:0090132 119 0.017
locomotory behavior GO:0007626 1 0.017
positive regulation of hydrolase activity GO:0051345 331 0.017
positive regulation of nucleoside metabolic process GO:0045979 186 0.017
hindbrain development GO:0030902 3 0.017
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.016
regulation of growth GO:0040008 165 0.016
response to abiotic stimulus GO:0009628 336 0.016
ectodermal placode formation GO:0060788 1 0.016
regulation of cell morphogenesis GO:0022604 153 0.016
positive regulation of developmental process GO:0051094 314 0.016
epithelial cell differentiation GO:0030855 141 0.016
negative regulation of protein phosphorylation GO:0001933 140 0.016
epithelium development GO:0060429 227 0.016
regulation of reactive oxygen species metabolic process GO:2000377 41 0.016
positive regulation of phosphorylation GO:0042327 394 0.016
engulfment of apoptotic cell GO:0043652 2 0.016
positive regulation of apoptotic process GO:0043065 246 0.016
regulation of protein serine threonine kinase activity GO:0071900 179 0.016
peripheral nervous system development GO:0007422 2 0.016
atp catabolic process GO:0006200 157 0.016
protein glycosylation GO:0006486 62 0.016
glycosylation GO:0070085 71 0.016
ion transmembrane transport GO:0034220 338 0.016
regulation of proteolysis GO:0030162 293 0.016
protein targeting GO:0006605 187 0.016
g1 s transition of mitotic cell cycle GO:0000082 78 0.016
inner ear morphogenesis GO:0042472 4 0.016
blood vessel morphogenesis GO:0048514 162 0.016
regulation of cell projection assembly GO:0060491 47 0.016
negative regulation of multicellular organismal process GO:0051241 317 0.016
mitotic nuclear division GO:0007067 119 0.015
lipid localization GO:0010876 106 0.015
regulation of rho gtpase activity GO:0032319 66 0.015
rhythmic behavior GO:0007622 2 0.015
chromatin organization GO:0006325 351 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.015
regulation of actin cytoskeleton organization GO:0032956 116 0.015
single organism reproductive process GO:0044702 98 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.015
cell type specific apoptotic process GO:0097285 125 0.015
fatty acid metabolic process GO:0006631 115 0.015
regulation of dephosphorylation GO:0035303 96 0.015
ribonucleoside monophosphate metabolic process GO:0009161 187 0.015
positive regulation of cytokine production GO:0001819 167 0.015
positive regulation of mapk cascade GO:0043410 190 0.015
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.015
negative regulation of cell growth GO:0030308 83 0.015
regulation of mapk cascade GO:0043408 262 0.015
cytokine production GO:0001816 247 0.015
regulation of cell adhesion GO:0030155 166 0.015
regulation of neurogenesis GO:0050767 82 0.015
biological adhesion GO:0022610 331 0.015
viral process GO:0016032 146 0.015
regeneration GO:0031099 4 0.014
positive regulation of programmed cell death GO:0043068 249 0.014
histone methylation GO:0016571 60 0.014
organophosphate biosynthetic process GO:0090407 163 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
establishment of protein localization to organelle GO:0072594 172 0.014
negative regulation of rho gtpase activity GO:0034259 4 0.014
mitotic cell cycle phase transition GO:0044772 162 0.014
anion transport GO:0006820 161 0.014
secretion by cell GO:0032940 226 0.014
nucleoside monophosphate metabolic process GO:0009123 191 0.014
mating GO:0007618 1 0.014
reactive nitrogen species metabolic process GO:2001057 3 0.014
macromolecule glycosylation GO:0043413 63 0.014
regulation of cell differentiation GO:0045595 393 0.014
cell projection assembly GO:0030031 126 0.014
tube closure GO:0060606 3 0.014
chemotaxis GO:0006935 157 0.014
regulation of protein complex assembly GO:0043254 147 0.014
apoptotic signaling pathway GO:0097190 268 0.014
purine nucleoside monophosphate metabolic process GO:0009126 186 0.014
central nervous system neuron axonogenesis GO:0021955 3 0.014
establishment of organelle localization GO:0051656 59 0.014
regulation of cellular component biogenesis GO:0044087 281 0.014
sex determination GO:0007530 3 0.014
hemopoiesis GO:0030097 180 0.014
cellular response to cytokine stimulus GO:0071345 181 0.014
transmembrane transport GO:0055085 399 0.014
hippocampus development GO:0021766 1 0.014
ubiquitin dependent protein catabolic process GO:0006511 206 0.014
nucleocytoplasmic transport GO:0006913 176 0.014
negative regulation of cell motility GO:2000146 104 0.014
metencephalon development GO:0022037 2 0.013
negative regulation of locomotion GO:0040013 118 0.013
meiosis i GO:0007127 4 0.013
peptidyl tyrosine phosphorylation GO:0018108 170 0.013
positive regulation of organelle organization GO:0010638 195 0.013
protein ubiquitination GO:0016567 314 0.013
cellular protein catabolic process GO:0044257 261 0.013
regulation of neural precursor cell proliferation GO:2000177 4 0.013
negative regulation of cell development GO:0010721 48 0.013
atp metabolic process GO:0046034 176 0.013
stem cell division GO:0017145 2 0.013
nuclear division GO:0000280 128 0.013
tube development GO:0035295 125 0.013
cilium morphogenesis GO:0060271 75 0.013
positive regulation of endocytosis GO:0045807 42 0.013
methylation GO:0032259 106 0.013
epithelial cell proliferation GO:0050673 128 0.013
sequestering of metal ion GO:0051238 24 0.013
late endosome to vacuole transport GO:0045324 2 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.013
small gtpase mediated signal transduction GO:0007264 78 0.013
primary neural tube formation GO:0014020 3 0.013
positive regulation of rho gtpase activity GO:0032321 56 0.013
regulation of viral process GO:0050792 103 0.013
synaptic vesicle recycling GO:0036465 3 0.013
organonitrogen compound biosynthetic process GO:1901566 200 0.013
protein oligomerization GO:0051259 173 0.012
cardiovascular system development GO:0072358 262 0.012
morphogenesis of a polarized epithelium GO:0001738 3 0.012
regulation of ion transport GO:0043269 189 0.012
central nervous system development GO:0007417 123 0.012
regulation of endopeptidase activity GO:0052548 170 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
regulation of dna metabolic process GO:0051052 153 0.012
immune response GO:0006955 307 0.012
regulation of mitotic cell cycle phase transition GO:1901990 118 0.012
positive regulation of protein transport GO:0051222 135 0.012
cellular macromolecule catabolic process GO:0044265 380 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
positive regulation of axon extension GO:0045773 4 0.012
negative regulation of blood pressure GO:0045776 3 0.012
cellular response to external stimulus GO:0071496 111 0.012
protein acylation GO:0043543 138 0.012
positive regulation of cell cycle GO:0045787 140 0.012
chromosome segregation GO:0007059 114 0.012
regulation of cysteine type endopeptidase activity GO:2000116 127 0.012
somitogenesis GO:0001756 2 0.012
cell cycle g1 s phase transition GO:0044843 80 0.012
calcium ion transport GO:0006816 147 0.012
cellular component disassembly GO:0022411 92 0.012
regulation of nucleotide catabolic process GO:0030811 205 0.012
rab protein signal transduction GO:0032482 4 0.012
establishment or maintenance of cell polarity GO:0007163 31 0.012
immune system development GO:0002520 195 0.012
tube morphogenesis GO:0035239 95 0.012
cellular response to extracellular stimulus GO:0031668 72 0.012
aging GO:0007568 66 0.012
membrane fusion GO:0061025 43 0.012
protein maturation GO:0051604 233 0.012
peptidyl tyrosine modification GO:0018212 170 0.011
peptidyl lysine modification GO:0018205 144 0.011
regulation of cell cycle process GO:0010564 266 0.011
antigen processing and presentation GO:0019882 33 0.011
peptidyl threonine modification GO:0018210 45 0.011
tongue development GO:0043586 1 0.011
negative regulation of phosphatase activity GO:0010923 61 0.011
regulation of carbohydrate metabolic process GO:0006109 54 0.011
negative regulation of cell migration GO:0030336 102 0.011
negative regulation of protein kinase activity GO:0006469 98 0.011
brain development GO:0007420 97 0.011
embryo development GO:0009790 123 0.011
autophagy GO:0006914 88 0.011
cation transmembrane transport GO:0098655 238 0.011
actin filament based movement GO:0030048 17 0.011
regulation of protein polymerization GO:0032271 63 0.011
regulation of epithelial cell proliferation GO:0050678 113 0.011
innate immune response GO:0045087 178 0.011
positive regulation of peptidase activity GO:0010952 88 0.011
negative regulation of growth GO:0045926 97 0.011
vasculature development GO:0001944 181 0.011
ameboidal type cell migration GO:0001667 135 0.011
sleep GO:0030431 2 0.011
regulation of protein transport GO:0051223 213 0.011
negative regulation of cellular catabolic process GO:0031330 83 0.011
blood vessel development GO:0001568 172 0.011
brain morphogenesis GO:0048854 1 0.011
hematopoietic or lymphoid organ development GO:0048534 186 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.011
head development GO:0060322 108 0.011
cellular response to nutrient levels GO:0031669 69 0.011
central nervous system projection neuron axonogenesis GO:0021952 3 0.011
endocardial cushion development GO:0003197 3 0.011
regulation of sarcomere organization GO:0060297 3 0.011
histone acetylation GO:0016573 93 0.011
negative regulation of synaptic transmission GO:0050805 2 0.011
visual behavior GO:0007632 2 0.011

APPL2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.034
cancer DOID:162 167 0.034
organ system cancer DOID:0050686 164 0.034
disease of cellular proliferation DOID:14566 174 0.034
musculoskeletal system disease DOID:17 223 0.029
cardiovascular system disease DOID:1287 106 0.025
muscular disease DOID:0080000 114 0.023
central nervous system disease DOID:331 186 0.019
nervous system disease DOID:863 431 0.019
sensory system disease DOID:0050155 203 0.015
myopathy DOID:423 104 0.014
muscular dystrophy DOID:9884 51 0.014
muscle tissue disease DOID:66 113 0.014
connective tissue disease DOID:65 109 0.014
immune system disease DOID:2914 155 0.014
heart disease DOID:114 68 0.013
brain disease DOID:936 73 0.012
gastrointestinal system cancer DOID:3119 52 0.012
hematopoietic system disease DOID:74 100 0.011
eye and adnexa disease DOID:1492 150 0.011