|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
1.000
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
1.000
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.999
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.999
|
|
|
|
extraocular skeletal muscle development
|
GO:0002074 |
1 |
0.998
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.998
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.997
|
|
|
|
negative regulation of cell fate commitment
|
GO:0010454 |
3 |
0.997
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.997
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.996
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.995
|
Mouse |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.995
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.993
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.993
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.990
|
Mouse |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.989
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.989
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.989
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.988
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.986
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.984
|
|
|
|
response to estradiol
|
GO:0032355 |
23 |
0.984
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.983
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.982
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.982
|
|
|
|
negative regulation of cell fate specification
|
GO:0009996 |
3 |
0.980
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.979
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.979
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.979
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.977
|
Mouse |
|
|
vasculature development
|
GO:0001944 |
181 |
0.976
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.974
|
Mouse |
|
|
chromatin modification
|
GO:0016568 |
298 |
0.974
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.974
|
Mouse |
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.970
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.969
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.969
|
Mouse |
|
|
response to lipid
|
GO:0033993 |
206 |
0.966
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.965
|
|
|
|
regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033143 |
32 |
0.963
|
Mouse |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.960
|
|
|
|
carbon catabolite activation of transcription
|
GO:0045991 |
3 |
0.956
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.956
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.956
|
|
|
|
positive regulation of glucocorticoid receptor signaling pathway
|
GO:2000324 |
1 |
0.954
|
|
|
|
positive regulation of erythrocyte differentiation
|
GO:0045648 |
11 |
0.953
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.948
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.948
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.947
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.947
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.945
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.944
|
Mouse |
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.944
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.944
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.943
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.941
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.941
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.938
|
|
|
|
regulation of activin receptor signaling pathway
|
GO:0032925 |
14 |
0.936
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.934
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.931
|
Mouse |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.928
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.928
|
|
|
|
carbon catabolite activation of transcription from rna polymerase ii promoter
|
GO:0000436 |
3 |
0.926
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.924
|
|
|
|
mating
|
GO:0007618 |
1 |
0.923
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.922
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.921
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.920
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
47 |
0.919
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.918
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.914
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.913
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.910
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.908
|
Mouse |
|
|
skin development
|
GO:0043588 |
76 |
0.905
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.903
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.901
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.898
|
Mouse |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.892
|
|
|
|
positive regulation of feeding behavior
|
GO:2000253 |
1 |
0.891
|
|
|
|
positive regulation of transcription by galactose
|
GO:0000411 |
1 |
0.890
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.890
|
Mouse |
|
|
odontogenesis
|
GO:0042476 |
25 |
0.889
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.884
|
Mouse |
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.882
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.882
|
Mouse |
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.880
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.879
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.875
|
|
|
|
regulation of glucose metabolic process
|
GO:0010906 |
28 |
0.873
|
|
|
|
regulation of muscle cell differentiation
|
GO:0051147 |
31 |
0.872
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.872
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.870
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.869
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.868
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.865
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.864
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.861
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.859
|
|
|
|
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter
|
GO:0072364 |
3 |
0.855
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.855
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.854
|
|
|
|
mesoderm development
|
GO:0007498 |
14 |
0.853
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.849
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.848
|
|
|
|
intracellular estrogen receptor signaling pathway
|
GO:0030520 |
23 |
0.848
|
Mouse |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.839
|
|
|
|
neuroendocrine cell differentiation
|
GO:0061101 |
2 |
0.835
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.835
|
|
|
|
carbon catabolite regulation of transcription from rna polymerase ii promoter
|
GO:0000429 |
3 |
0.834
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.829
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.828
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.825
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.824
|
Mouse |
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.821
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.820
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.817
|
|
|
|
epithelial tube branching involved in lung morphogenesis
|
GO:0060441 |
4 |
0.816
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.815
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.813
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.804
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.803
|
|
|
|
positive regulation of gluconeogenesis
|
GO:0045722 |
1 |
0.801
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.801
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.798
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.792
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.787
|
|
|
|
hormone metabolic process
|
GO:0042445 |
61 |
0.781
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.777
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.776
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.774
|
Rat |
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.769
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.769
|
|
|
|
hexose metabolic process
|
GO:0019318 |
55 |
0.765
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.765
|
Mouse |
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.763
|
|
|
|
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter
|
GO:0072366 |
1 |
0.761
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.759
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.758
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.757
|
|
|
|
androgen receptor signaling pathway
|
GO:0030521 |
34 |
0.756
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.750
|
|
|
|
response to hyperoxia
|
GO:0055093 |
4 |
0.746
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.738
|
|
|
|
hormone mediated signaling pathway
|
GO:0009755 |
22 |
0.737
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.733
|
|
|
|
pituitary gland development
|
GO:0021983 |
2 |
0.723
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.717
|
|
|
|
regulation of muscle organ development
|
GO:0048634 |
27 |
0.710
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.709
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
42 |
0.708
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
8 |
0.698
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.691
|
|
|
|
negative regulation of stem cell differentiation
|
GO:2000737 |
22 |
0.690
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.687
|
|
|
|
prostate gland stromal morphogenesis
|
GO:0060741 |
1 |
0.687
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.684
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.683
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.681
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
36 |
0.680
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.675
|
Mouse |
|
|
response to alcohol
|
GO:0097305 |
64 |
0.672
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.669
|
Rat |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.666
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.666
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.665
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.665
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.657
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.651
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.650
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.648
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.645
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.641
|
|
|
|
regulation of smooth muscle cell differentiation
|
GO:0051150 |
3 |
0.639
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.636
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.636
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.634
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.632
|
Mouse Rat |
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.632
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.632
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.630
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.630
|
|
|
|
embryonic forelimb morphogenesis
|
GO:0035115 |
4 |
0.625
|
|
|
|
smooth muscle cell differentiation
|
GO:0051145 |
8 |
0.620
|
|
|
|
regulation of triglyceride metabolic process
|
GO:0090207 |
11 |
0.617
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.617
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.614
|
|
|
|
hard palate development
|
GO:0060022 |
1 |
0.610
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.609
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.608
|
|
|
|
glucose metabolic process
|
GO:0006006 |
45 |
0.608
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.600
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.599
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.597
|
|
|
|
cell fate specification
|
GO:0001708 |
8 |
0.596
|
Mouse |
|
|
urogenital system development
|
GO:0001655 |
65 |
0.594
|
Mouse |
|
|
regulation of epidermis development
|
GO:0045682 |
19 |
0.591
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.588
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.585
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.583
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.581
|
|
|
|
positive regulation of epithelial cell differentiation
|
GO:0030858 |
14 |
0.577
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.573
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.570
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.563
|
|
|
|
negative regulation of developmental growth
|
GO:0048640 |
10 |
0.562
|
|
|
|
head development
|
GO:0060322 |
108 |
0.556
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.552
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.551
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.551
|
|
|
|
regulation of glucocorticoid receptor signaling pathway
|
GO:2000322 |
2 |
0.545
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.545
|
Mouse |
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.545
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.543
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.543
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
47 |
0.541
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
11 |
0.537
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.532
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.531
|
Mouse |
|
|
heart development
|
GO:0007507 |
95 |
0.530
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
17 |
0.528
|
|
|
|
dna templated transcription initiation
|
GO:0006352 |
35 |
0.527
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.527
|
|
|
|
regulation of transcription by galactose
|
GO:0000409 |
1 |
0.525
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.524
|
|
|
|
menstrual cycle phase
|
GO:0022601 |
2 |
0.520
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.517
|
Mouse Rat |
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.514
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.509
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation
|
GO:0003257 |
3 |
0.507
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.505
|
|
|
|
glucose homeostasis
|
GO:0042593 |
31 |
0.501
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.498
|
|
|
|
fat cell differentiation
|
GO:0045444 |
32 |
0.497
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.496
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.494
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.494
|
|
|
|
positive regulation of autophagy
|
GO:0010508 |
24 |
0.490
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.488
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus
|
GO:1901522 |
2 |
0.488
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.486
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.479
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.478
|
Rat |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.473
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.472
|
|
|
|
negative regulation of g0 to g1 transition
|
GO:0070317 |
2 |
0.472
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.472
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.468
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.467
|
|
|
|
positive regulation of epidermis development
|
GO:0045684 |
11 |
0.467
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.462
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.462
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.461
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.460
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
23 |
0.460
|
|
|
|
biological phase
|
GO:0044848 |
5 |
0.460
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.455
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.453
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.450
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.450
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.446
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.446
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.442
|
|
|
|
cellular glucan metabolic process
|
GO:0006073 |
22 |
0.440
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.439
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.436
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.435
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.435
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.433
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.430
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.430
|
|
|
|
corticosteroid receptor signaling pathway
|
GO:0031958 |
5 |
0.427
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.424
|
|
|
|
growth
|
GO:0040007 |
202 |
0.417
|
Mouse |
|
|
response to nitric oxide
|
GO:0071731 |
4 |
0.414
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.409
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.405
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
33 |
0.405
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.404
|
|
|
|
thymus development
|
GO:0048538 |
3 |
0.404
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
23 |
0.403
|
Mouse |
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
41 |
0.400
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.399
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.397
|
Rat |
|
|
segmentation
|
GO:0035282 |
4 |
0.396
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.392
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.389
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.388
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.384
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.383
|
|
|
|
regulation of carbohydrate biosynthetic process
|
GO:0043255 |
27 |
0.381
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.377
|
Mouse |
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
43 |
0.373
|
|
|
|
endocrine system development
|
GO:0035270 |
26 |
0.369
|
|
|
|
neural tube patterning
|
GO:0021532 |
2 |
0.369
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.364
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.364
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.363
|
Mouse |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.359
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.359
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.358
|
|
|
|
cardiac muscle cell cardiac muscle cell adhesion
|
GO:0086042 |
1 |
0.355
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.353
|
|
|
|
acylglycerol metabolic process
|
GO:0006639 |
27 |
0.347
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.346
|
|
|
|
glucan metabolic process
|
GO:0044042 |
22 |
0.346
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.346
|
|
|
|
negative regulation of muscle cell differentiation
|
GO:0051148 |
17 |
0.342
|
|
|
|
lung morphogenesis
|
GO:0060425 |
6 |
0.341
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.341
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.337
|
|
|
|
regulation of cardioblast differentiation
|
GO:0051890 |
4 |
0.337
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.336
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.334
|
|
|
|
positive regulation of cardiac muscle cell differentiation
|
GO:2000727 |
4 |
0.332
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.332
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.332
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.332
|
|
|
|
smooth muscle cell proliferation
|
GO:0048659 |
28 |
0.328
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
25 |
0.323
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.321
|
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.319
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.316
|
|
|
|
cellular response to increased oxygen levels
|
GO:0036295 |
4 |
0.313
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.312
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.312
|
|
|
|
carbon catabolite regulation of transcription
|
GO:0045990 |
5 |
0.310
|
|
|
|
negative regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060633 |
3 |
0.307
|
|
|
|
male gonad development
|
GO:0008584 |
23 |
0.306
|
Mouse |
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.302
|
|
|
|
myotube differentiation
|
GO:0014902 |
22 |
0.301
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.297
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.297
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
45 |
0.294
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.291
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.290
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.289
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.288
|
Mouse |
|
|
response to increased oxygen levels
|
GO:0036296 |
4 |
0.288
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.286
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.286
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.283
|
|
|
|
positive regulation of epidermal cell differentiation
|
GO:0045606 |
8 |
0.281
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.279
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
4 |
0.278
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.276
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.275
|
|
|
|
endoderm formation
|
GO:0001706 |
33 |
0.275
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
27 |
0.274
|
|
|
|
prostate gland morphogenesis
|
GO:0060512 |
1 |
0.272
|
Mouse |
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.272
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
22 |
0.268
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.267
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.267
|
|
|
|
heart formation
|
GO:0060914 |
2 |
0.266
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.265
|
|
|
|
regulation of gluconeogenesis by regulation of transcription from rna polymerase ii promoter
|
GO:0035947 |
1 |
0.265
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.264
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.262
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.260
|
|
|
|
response to low density lipoprotein particle
|
GO:0055098 |
4 |
0.258
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.256
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.253
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.253
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.252
|
Rat |
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.250
|
|
|
|
ectoderm development
|
GO:0007398 |
3 |
0.250
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
17 |
0.249
|
|
|
|
positive regulation of glucose metabolic process
|
GO:0010907 |
12 |
0.243
|
|
|
|
neuronal stem cell maintenance
|
GO:0097150 |
5 |
0.243
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.242
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.242
|
|
|
|
transcription initiation from rna polymerase ii promoter
|
GO:0006367 |
27 |
0.241
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.240
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
23 |
0.239
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.238
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.237
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.237
|
|
|
|
negative regulation of smooth muscle cell differentiation
|
GO:0051151 |
2 |
0.235
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
35 |
0.235
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.235
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.235
|
|
|
|
cardiac cell fate specification
|
GO:0060912 |
1 |
0.234
|
|
|
|
regulation of striated muscle tissue development
|
GO:0016202 |
26 |
0.232
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.231
|
|
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
18 |
0.228
|
|
|
|
positive regulation of triglyceride biosynthetic process
|
GO:0010867 |
4 |
0.227
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.225
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.225
|
|
|
|
neutral lipid metabolic process
|
GO:0006638 |
27 |
0.225
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.224
|
Rat |
|
|
lung associated mesenchyme development
|
GO:0060484 |
1 |
0.224
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.224
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.222
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.221
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.219
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.217
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.217
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
14 |
0.215
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.214
|
Mouse |
|
|
glycogen metabolic process
|
GO:0005977 |
22 |
0.213
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.212
|
|
|
|
positive regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033145 |
7 |
0.211
|
Mouse |
|
|
macroautophagy
|
GO:0016236 |
39 |
0.209
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.209
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.206
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.206
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.205
|
|
|
|
menstruation
|
GO:0042703 |
1 |
0.205
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.205
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
31 |
0.203
|
|
|
|
cellular response to nutrient
|
GO:0031670 |
12 |
0.203
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.202
|
Mouse |
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.201
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.200
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.200
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.198
|
|
|
|
regulation of cell fate specification
|
GO:0042659 |
5 |
0.197
|
Mouse |
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.194
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.193
|
Mouse |
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.193
|
|
|
|
negative regulation of protein binding
|
GO:0032091 |
35 |
0.193
|
|
|
|
circadian rhythm
|
GO:0007623 |
21 |
0.190
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.189
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.189
|
|
|
|
soft palate development
|
GO:0060023 |
3 |
0.186
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.186
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.186
|
|
|
|
response to starvation
|
GO:0042594 |
59 |
0.185
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.185
|
|
|
|
regulation of epithelial cell differentiation involved in kidney development
|
GO:2000696 |
4 |
0.185
|
|
|
|
regulation of steroid biosynthetic process
|
GO:0050810 |
23 |
0.183
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.181
|
|
|
|
nephron tubule epithelial cell differentiation
|
GO:0072160 |
3 |
0.181
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.181
|
Mouse |
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.181
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.179
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.178
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.176
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.175
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.175
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
16 |
0.175
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
26 |
0.173
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.173
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.170
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.170
|
|
|
|
mammary gland development
|
GO:0030879 |
17 |
0.169
|
Mouse |
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.169
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.168
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.168
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.166
|
Mouse |
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.164
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.162
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
14 |
0.161
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.161
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.161
|
|
|
|
stem cell maintenance
|
GO:0019827 |
19 |
0.159
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.159
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.159
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.158
|
|
|
|
skeletal muscle tissue development
|
GO:0007519 |
24 |
0.158
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.156
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.156
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.155
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.155
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.154
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.153
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.153
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.152
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.152
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.152
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.151
|
|
|
|
negative regulation of transcription by competitive promoter binding
|
GO:0010944 |
8 |
0.149
|
|
|
|
male sex differentiation
|
GO:0046661 |
25 |
0.147
|
Mouse Rat |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.146
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.146
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.145
|
Mouse |
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.145
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.145
|
|
|
|
regulation of multicellular organism growth
|
GO:0040014 |
8 |
0.144
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.143
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.140
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.139
|
|
|
|
rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0051123 |
4 |
0.139
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
23 |
0.139
|
|
|
|
cellular aldehyde metabolic process
|
GO:0006081 |
20 |
0.138
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.138
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.136
|
Mouse |
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.136
|
|
