Homo sapiens

77 known processes

ARHGEF11

Rho guanine nucleotide exchange factor (GEF) 11

(Aliases: KIAA0380,DKFZp667F1223,PDZ-RHOGEF,GTRAP48)

ARHGEF11 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
semaphorin plexin signaling pathway GO:0071526 4 0.999
rho protein signal transduction GO:0007266 26 0.965
ras protein signal transduction GO:0007265 73 0.943
guanosine containing compound metabolic process GO:1901068 244 0.932
Fly
gtp catabolic process GO:0006184 237 0.920
Fly
purine nucleoside catabolic process GO:0006152 398 0.914
Fly
small gtpase mediated signal transduction GO:0007264 78 0.894
purine ribonucleotide catabolic process GO:0009154 404 0.876
Fly
nucleoside triphosphate catabolic process GO:0009143 394 0.875
Fly
ribonucleoside catabolic process GO:0042454 406 0.849
Fly
nucleotide catabolic process GO:0009166 408 0.848
Fly
positive regulation of gtpase activity GO:0043547 166 0.847
Fly
purine nucleoside triphosphate catabolic process GO:0009146 392 0.843
Fly
purine ribonucleoside metabolic process GO:0046128 437 0.837
Fly
regulation of gtpase activity GO:0043087 180 0.832
Fly
glycosyl compound catabolic process GO:1901658 413 0.830
Fly
guanosine containing compound catabolic process GO:1901069 239 0.823
Fly
regulation of rho gtpase activity GO:0032319 66 0.816
Fly
nucleoside phosphate catabolic process GO:1901292 412 0.813
Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.808
Fly
ribonucleotide catabolic process GO:0009261 405 0.806
Fly
purine nucleotide catabolic process GO:0006195 405 0.804
Fly
regulation of purine nucleotide catabolic process GO:0033121 205 0.764
Fly
purine ribonucleoside catabolic process GO:0046130 398 0.745
Fly
positive regulation of ras gtpase activity GO:0032320 117 0.733
Fly
organophosphate catabolic process GO:0046434 430 0.717
Fly
bone maturation GO:0070977 5 0.700
positive regulation of gtp catabolic process GO:0033126 166 0.700
Fly
regulation of anatomical structure morphogenesis GO:0022603 286 0.682
Fly
regulation of nucleotide metabolic process GO:0006140 269 0.677
Fly
regulation of ras gtpase activity GO:0032318 128 0.672
Fly
nucleoside triphosphate metabolic process GO:0009141 422 0.653
Fly
purine nucleoside triphosphate metabolic process GO:0009144 412 0.650
Fly
purine containing compound catabolic process GO:0072523 411 0.641
Fly
ribonucleoside triphosphate catabolic process GO:0009203 391 0.629
Fly
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.624
Fly
regulation of rho protein signal transduction GO:0035023 79 0.608
Fly
positive regulation of rho gtpase activity GO:0032321 56 0.607
Fly
nucleoside catabolic process GO:0009164 408 0.576
Fly
ossification involved in bone maturation GO:0043931 4 0.573
positive regulation of hydrolase activity GO:0051345 331 0.554
Fly
regulation of cytoskeleton organization GO:0051493 177 0.537
Zebrafish
regulation of ras protein signal transduction GO:0046578 155 0.508
Fly
regulation of gtp catabolic process GO:0033124 180 0.485
Fly
positive regulation of nucleotide catabolic process GO:0030813 185 0.484
Fly
endothelial cell proliferation GO:0001935 65 0.457
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.456
Fly
positive regulation of catabolic process GO:0009896 310 0.441
Fly
regulation of nucleotide catabolic process GO:0030811 205 0.439
Fly
regulation of neuron differentiation GO:0045664 70 0.435
Fly
ribonucleoside triphosphate metabolic process GO:0009199 412 0.432
Fly
regulation of cell differentiation GO:0045595 393 0.400
Fly
regulation of nucleoside metabolic process GO:0009118 209 0.396
Fly
regulation of small gtpase mediated signal transduction GO:0051056 156 0.378
Fly
negative regulation of nucleotide catabolic process GO:0030812 16 0.378
gtp metabolic process GO:0046039 239 0.371
Fly
cell chemotaxis GO:0060326 112 0.360
bone trabecula morphogenesis GO:0061430 1 0.351
organ maturation GO:0048799 5 0.336
regulation of endothelial cell proliferation GO:0001936 56 0.333
regulation of cell shape GO:0008360 48 0.318
Fly
positive regulation of cellular catabolic process GO:0031331 284 0.298
Fly
trabecula morphogenesis GO:0061383 2 0.289
regulation of purine nucleotide metabolic process GO:1900542 264 0.273
Fly
chemotaxis GO:0006935 157 0.242
positive regulation of endothelial cell proliferation GO:0001938 37 0.241
positive regulation of cellular component organization GO:0051130 376 0.241
regulation of locomotion GO:0040012 329 0.240
regulation of cellular component movement GO:0051270 334 0.232
regulation of cell morphogenesis GO:0022604 153 0.227
Fly
forebrain generation of neurons GO:0021872 3 0.213
cell projection organization GO:0030030 252 0.212
Fly
establishment of planar polarity GO:0001736 3 0.206
cell morphogenesis GO:0000902 296 0.205
Fly
negative regulation of nucleoside metabolic process GO:0045978 18 0.205
positive regulation of nucleotide metabolic process GO:0045981 230 0.199
Fly
positive regulation of epithelial cell proliferation GO:0050679 65 0.194
neuron projection development GO:0031175 106 0.194
Fly
negative regulation of catabolic process GO:0009895 104 0.193
negative regulation of cell migration GO:0030336 102 0.172
biological adhesion GO:0022610 331 0.169
negative regulation of phosphorus metabolic process GO:0010563 267 0.168
regulation of neurogenesis GO:0050767 82 0.168
Fly
morphogenesis of embryonic epithelium GO:0016331 4 0.164
Fly
osteoblast proliferation GO:0033687 8 0.151
regulation of cell motility GO:2000145 299 0.149
negative regulation of phosphate metabolic process GO:0045936 267 0.148
positive regulation of nucleoside metabolic process GO:0045979 186 0.145
Fly
regulation of cellular component biogenesis GO:0044087 281 0.141
nervous system development GO:0007399 293 0.140
Fly
positive regulation of developmental process GO:0051094 314 0.134
regulation of cell migration GO:0030334 289 0.133
negative regulation of cellular component movement GO:0051271 106 0.130
cell development GO:0048468 328 0.128
Fly
regulation of cell adhesion GO:0030155 166 0.127
regulation of cell development GO:0060284 161 0.123
Fly
negative regulation of locomotion GO:0040013 118 0.122
neuron differentiation GO:0030182 138 0.119
Fly
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.116
Fly
negative regulation of cellular catabolic process GO:0031330 83 0.113
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.113
neuromuscular junction development GO:0007528 3 0.113
regulation of cell projection organization GO:0031344 107 0.113
Fly
cell adhesion GO:0007155 325 0.112
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.111
Fly
actin filament based movement GO:0030048 17 0.107
Fly
negative regulation of cell motility GO:2000146 104 0.107
epithelial cell proliferation GO:0050673 128 0.106
anatomical structure maturation GO:0071695 9 0.105
mitotic cytokinetic process GO:1902410 2 0.105
positive regulation of rho protein signal transduction GO:0035025 4 0.104
Fly
actin filament organization GO:0007015 128 0.104
Zebrafish Fly
regulation of epithelial cell proliferation GO:0050678 113 0.100
negative regulation of nucleotide metabolic process GO:0045980 29 0.100
oogenesis GO:0048477 2 0.100
taxis GO:0042330 157 0.098
negative regulation of catalytic activity GO:0043086 335 0.098
negative regulation of cell adhesion GO:0007162 64 0.097
regulation of nervous system development GO:0051960 88 0.096
Fly
positive chemotaxis GO:0050918 33 0.096
negative regulation of cell proliferation GO:0008285 228 0.095
establishment of tissue polarity GO:0007164 3 0.095
positive regulation of phosphorylation GO:0042327 394 0.094
female gamete generation GO:0007292 2 0.087
positive regulation of cell development GO:0010720 92 0.087
post embryonic development GO:0009791 2 0.086
Fly
regulation of neuron projection development GO:0010975 57 0.081
Fly
locomotory behavior GO:0007626 1 0.077
cerebral cortex cell migration GO:0021795 3 0.075
cellular component morphogenesis GO:0032989 314 0.074
Fly
actin filament based process GO:0030029 224 0.068
Zebrafish Fly
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.067
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.067
actin mediated cell contraction GO:0070252 12 0.065
Fly
positive regulation of amine transport GO:0051954 2 0.064
cation transport GO:0006812 331 0.064
ossification GO:0001503 121 0.063
cellular ketone metabolic process GO:0042180 80 0.061
morphogenesis of a polarized epithelium GO:0001738 3 0.059
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.059
neuroblast proliferation GO:0007405 4 0.058
ion homeostasis GO:0050801 230 0.057
bleb assembly GO:0032060 6 0.056
neuron development GO:0048666 113 0.055
Fly
negative regulation of cellular component organization GO:0051129 235 0.055
cell morphogenesis involved in differentiation GO:0000904 144 0.053
Fly
cell type specific apoptotic process GO:0097285 125 0.051
embryonic epithelial tube formation GO:0001838 4 0.050
mechanosensory behavior GO:0007638 4 0.050
Worm
multicellular organismal aging GO:0010259 3 0.049
positive regulation of organelle organization GO:0010638 195 0.048
positive regulation of nervous system development GO:0051962 54 0.047
cell part morphogenesis GO:0032990 137 0.047
Fly
cell projection morphogenesis GO:0048858 129 0.047
Fly
neurogenesis GO:0022008 169 0.045
Fly
negative regulation of developmental process GO:0051093 247 0.045
regulation of cellular amino acid metabolic process GO:0006521 6 0.044
negative regulation of hydrolase activity GO:0051346 182 0.044
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.043
regulation of actin cytoskeleton organization GO:0032956 116 0.043
Zebrafish
cytoplasmic transport GO:0016482 379 0.043
skeletal system development GO:0001501 79 0.043
positive regulation of cell differentiation GO:0045597 211 0.043
positive regulation of rac gtpase activity GO:0032855 31 0.043
mitotic cell cycle GO:0000278 326 0.043
peripheral nervous system development GO:0007422 2 0.042
positive regulation of cell projection organization GO:0031346 64 0.041
epithelial cell development GO:0002064 34 0.041
neurological system process GO:0050877 163 0.041
Worm
lipid metabolic process GO:0006629 381 0.040
positive regulation of protein phosphorylation GO:0001934 313 0.040
inorganic ion transmembrane transport GO:0098660 231 0.039
vesicle mediated transport GO:0016192 371 0.039
cellular homeostasis GO:0019725 196 0.039
phosphatidylinositol mediated signaling GO:0048015 55 0.039
neural tube formation GO:0001841 3 0.038
maintenance of location GO:0051235 112 0.038
cardiovascular system development GO:0072358 262 0.038
oocyte differentiation GO:0009994 2 0.038
generation of neurons GO:0048699 152 0.038
Fly
cellular amine metabolic process GO:0044106 41 0.038
determination of adult lifespan GO:0008340 2 0.038
neurotransmitter secretion GO:0007269 4 0.038
metal ion homeostasis GO:0055065 169 0.037
axonogenesis GO:0007409 31 0.037
Fly
cation transmembrane transport GO:0098655 238 0.037
amine metabolic process GO:0009308 44 0.036
rab protein signal transduction GO:0032482 4 0.035
mitotic cell cycle process GO:1903047 286 0.035
regulation of cytoplasmic transport GO:1903649 149 0.035
acetylcholine transport GO:0015870 1 0.035
epithelium development GO:0060429 227 0.034
Fly
positive regulation of synaptic transmission GO:0050806 4 0.034
anatomical structure formation involved in morphogenesis GO:0048646 284 0.034
Fly
cellular response to histamine GO:0071420 3 0.034
ion transmembrane transport GO:0034220 338 0.034
negative regulation of purine nucleotide catabolic process GO:0033122 16 0.033
calcium ion homeostasis GO:0055074 122 0.033
regulation of actin filament based process GO:0032970 141 0.033
Zebrafish
primary neural tube formation GO:0014020 3 0.033
regulation of cellular ketone metabolic process GO:0010565 50 0.033
defense response GO:0006952 315 0.032
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.032
regulation of osteoblast proliferation GO:0033688 8 0.032
regulation of cellular response to stress GO:0080135 244 0.032
response to wounding GO:0009611 168 0.032
regulation of protein transport GO:0051223 213 0.032
membrane organization GO:0061024 292 0.031
protein autophosphorylation GO:0046777 123 0.031
inositol lipid mediated signaling GO:0048017 55 0.031
adult locomotory behavior GO:0008344 1 0.031
cellular response to dna damage stimulus GO:0006974 379 0.031
secretion GO:0046903 254 0.031
oocyte development GO:0048599 1 0.031
transmembrane transport GO:0055085 399 0.030
rna processing GO:0006396 255 0.030
secretion by cell GO:0032940 226 0.030
negative regulation of cell death GO:0060548 345 0.030
positive regulation of transport GO:0051050 336 0.030
actin cytoskeleton organization GO:0030036 207 0.030
Zebrafish Fly
actin filament bundle assembly GO:0051017 54 0.029
Zebrafish
bone development GO:0060348 26 0.029
negative regulation of apoptotic process GO:0043066 316 0.029
angiogenesis GO:0001525 147 0.029
regulation of growth rate GO:0040009 1 0.029
positive regulation of protein kinase activity GO:0045860 190 0.029
positive regulation of neurogenesis GO:0050769 49 0.029
microtubule cytoskeleton organization GO:0000226 176 0.029
cellular calcium ion homeostasis GO:0006874 117 0.029
sensory perception GO:0007600 103 0.029
Worm
regulation of cellular amine metabolic process GO:0033238 11 0.029
cellular amino acid metabolic process GO:0006520 116 0.029
response to oxygen containing compound GO:1901700 369 0.028
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.028
metal ion transport GO:0030001 272 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
immune effector process GO:0002252 159 0.028
regulation of protein serine threonine kinase activity GO:0071900 179 0.028
intracellular protein transport GO:0006886 270 0.028
cellular protein catabolic process GO:0044257 261 0.028
chromatin organization GO:0006325 351 0.028
blood vessel development GO:0001568 172 0.027
peptidyl tyrosine modification GO:0018212 170 0.027
cellular macromolecule catabolic process GO:0044265 380 0.027
endomembrane system organization GO:0010256 196 0.027
cation homeostasis GO:0055080 189 0.027
g protein coupled receptor signaling pathway GO:0007186 207 0.026
signal transduction by phosphorylation GO:0023014 297 0.026
regeneration GO:0031099 4 0.025
regulation of neural precursor cell proliferation GO:2000177 4 0.025
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.025
nerve development GO:0021675 4 0.025
response to organic cyclic compound GO:0014070 204 0.025
negative regulation of multicellular organismal process GO:0051241 317 0.025
positive regulation of axonogenesis GO:0050772 9 0.025
endosomal transport GO:0016197 129 0.025
positive regulation of neuron differentiation GO:0045666 40 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.024
sensory perception of mechanical stimulus GO:0050954 37 0.024
Worm
nitrogen compound transport GO:0071705 191 0.024
wnt signaling pathway GO:0016055 156 0.024
regulation of intracellular transport GO:0032386 195 0.024
chemical homeostasis GO:0048878 306 0.024
regulation of protein localization GO:0032880 296 0.024
protein catabolic process GO:0030163 325 0.024
protein ubiquitination GO:0016567 314 0.024
innate immune response GO:0045087 178 0.024
growth GO:0040007 202 0.023
Fly
protein modification by small protein conjugation GO:0032446 342 0.023
cell fate determination GO:0001709 3 0.023
regulation of mapk cascade GO:0043408 262 0.023
regulation of ion transport GO:0043269 189 0.023
single organism cellular localization GO:1902580 332 0.023
divalent metal ion transport GO:0070838 152 0.023
chromatin modification GO:0016568 298 0.023
small molecule biosynthetic process GO:0044283 157 0.023
divalent inorganic cation homeostasis GO:0072507 136 0.023
positive regulation of cellular component biogenesis GO:0044089 158 0.023
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.022
blood vessel morphogenesis GO:0048514 162 0.022
response to abiotic stimulus GO:0009628 336 0.022
Worm
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.022
positive regulation of neuron projection development GO:0010976 34 0.022
endosome to lysosome transport GO:0008333 21 0.021
divalent inorganic cation transport GO:0072511 158 0.021
positive regulation of cellular amine metabolic process GO:0033240 7 0.021
calcium ion transport GO:0006816 147 0.021
organic hydroxy compound metabolic process GO:1901615 147 0.021
system process GO:0003008 349 0.021
Worm
tissue morphogenesis GO:0048729 96 0.021
Fly
epithelial cell differentiation GO:0030855 141 0.021
vasculature development GO:0001944 181 0.021
cellular lipid metabolic process GO:0044255 303 0.021
regulation of axon guidance GO:1902667 3 0.021
spermatid differentiation GO:0048515 4 0.021
segmentation GO:0035282 4 0.021
regulation of cell cycle process GO:0010564 266 0.021
anion transport GO:0006820 161 0.021
microtubule based process GO:0007017 210 0.021
Zebrafish
histone modification GO:0016570 251 0.020
response to nitrogen compound GO:1901698 184 0.020
regulation of ion homeostasis GO:2000021 73 0.020
developmental maturation GO:0021700 28 0.020
cellular divalent inorganic cation homeostasis GO:0072503 128 0.020
regulation of mitotic cell cycle GO:0007346 189 0.020
response to biotic stimulus GO:0009607 276 0.020
organophosphate biosynthetic process GO:0090407 163 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.020
apoptotic signaling pathway GO:0097190 268 0.020
regulation of establishment of protein localization GO:0070201 242 0.020
regulation of secretion GO:0051046 194 0.020
response to inorganic substance GO:0010035 127 0.019
motor neuron axon guidance GO:0008045 2 0.019
cytokine production GO:0001816 247 0.019
melanin metabolic process GO:0006582 1 0.019
cellular response to organic cyclic compound GO:0071407 127 0.019
single organism reproductive process GO:0044702 98 0.019
Fly
regulation of secretion by cell GO:1903530 177 0.019
response to radiation GO:0009314 151 0.019
tube closure GO:0060606 3 0.019
positive regulation of collateral sprouting GO:0048672 2 0.019
negative regulation of protein metabolic process GO:0051248 391 0.019
regulation of proteolysis GO:0030162 293 0.019
cranial nerve development GO:0021545 4 0.019
embryo development GO:0009790 123 0.019
Worm Fly
axis elongation GO:0003401 4 0.018
cellular ion homeostasis GO:0006873 168 0.018
positive regulation of mapk cascade GO:0043410 190 0.018
positive regulation of protein complex assembly GO:0031334 86 0.018
regulation of growth GO:0040008 165 0.018
proteasomal protein catabolic process GO:0010498 176 0.018
peptidyl lysine modification GO:0018205 144 0.018
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.018
developmental process involved in reproduction GO:0003006 66 0.018
Fly
regulation of axon extension involved in axon guidance GO:0048841 2 0.018
negative regulation of gtp catabolic process GO:0033125 11 0.018
immune response GO:0006955 307 0.018
cell projection assembly GO:0030031 126 0.018
covalent chromatin modification GO:0016569 254 0.018
cell substrate adhesion GO:0031589 132 0.018
collateral sprouting GO:0048668 2 0.017
anterior posterior axis specification GO:0009948 2 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.017
sequestering of calcium ion GO:0051208 17 0.017
compound eye development GO:0048749 1 0.017
protein targeting GO:0006605 187 0.017
regulation of protein complex assembly GO:0043254 147 0.017
hematopoietic or lymphoid organ development GO:0048534 186 0.017
cellular cation homeostasis GO:0030003 163 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
response to external biotic stimulus GO:0043207 261 0.017
negative regulation of cellular protein metabolic process GO:0032269 353 0.017
ubiquitin dependent protein catabolic process GO:0006511 206 0.017
cell matrix adhesion GO:0007160 85 0.017
regulation of dna metabolic process GO:0051052 153 0.017
internal peptidyl lysine acetylation GO:0018393 97 0.017
regulation of vesicle mediated transport GO:0060627 130 0.017
cellular response to endogenous stimulus GO:0071495 336 0.017
regulation of metal ion transport GO:0010959 120 0.017
neuron death GO:0070997 65 0.016
meiosis i GO:0007127 4 0.016
memory GO:0007613 3 0.016
regulation of neuron migration GO:2001222 3 0.016
regulation of cellular component size GO:0032535 82 0.016
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.016
positive regulation of rab gtpase activity GO:0032851 39 0.016
protein maturation GO:0051604 233 0.016
circulatory system development GO:0072359 262 0.016
regulation of calcium ion transport GO:0051924 79 0.016
negative regulation of vasculature development GO:1901343 43 0.016
regulation of kinase activity GO:0043549 314 0.016
neuron projection morphogenesis GO:0048812 50 0.016
Fly
spindle elongation GO:0051231 4 0.016
myosin filament assembly GO:0031034 2 0.016
neural tube closure GO:0001843 3 0.015
regulation of actin filament polymerization GO:0030833 50 0.015
regulation of transporter activity GO:0032409 82 0.015
mrna metabolic process GO:0016071 175 0.015
regulation of protein catabolic process GO:0042176 155 0.015
negative regulation of blood vessel morphogenesis GO:2000181 41 0.015
single organismal cell cell adhesion GO:0016337 148 0.015
actin filament bundle organization GO:0061572 54 0.015
Zebrafish
protein localization to organelle GO:0033365 280 0.015
cellular chemical homeostasis GO:0055082 180 0.015
positive regulation of kinase activity GO:0033674 204 0.015
ribonucleoside monophosphate catabolic process GO:0009158 158 0.015
negative regulation of protein modification process GO:0031400 200 0.015
negative regulation of protein phosphorylation GO:0001933 140 0.015
protein localization to adherens junction GO:0071896 2 0.015
brain development GO:0007420 97 0.015
regulation of transferase activity GO:0051338 355 0.015
regulation of immune response GO:0050776 201 0.015
cell growth GO:0016049 160 0.015
Fly
regulation of wnt signaling pathway GO:0030111 123 0.015
rhythmic behavior GO:0007622 2 0.015
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.015
mitotic spindle elongation GO:0000022 4 0.015
positive regulation of secretion GO:0051047 116 0.015
jnk cascade GO:0007254 80 0.015
rna catabolic process GO:0006401 71 0.015
maintenance of protein location in cell GO:0032507 56 0.015
regulation of cell cycle GO:0051726 393 0.015
alcohol metabolic process GO:0006066 114 0.015
negative regulation of protein transport GO:0051224 75 0.015
circadian behavior GO:0048512 2 0.015
organelle fission GO:0048285 149 0.014
regulation of actin filament bundle assembly GO:0032231 36 0.014
intracellular receptor signaling pathway GO:0030522 104 0.014
negative regulation of wnt signaling pathway GO:0030178 69 0.014
sodium ion transport GO:0006814 61 0.014
negative regulation of cytoskeleton organization GO:0051494 45 0.014
regulation of cytokine production GO:0001817 232 0.014
negative regulation of organelle organization GO:0010639 126 0.014
organ formation GO:0048645 3 0.014
regulation of response to wounding GO:1903034 101 0.014
maintenance of protein location GO:0045185 57 0.014
actomyosin structure organization GO:0031032 59 0.014
Zebrafish
protein secretion GO:0009306 98 0.014
positive regulation of programmed cell death GO:0043068 249 0.014
regulation of actin polymerization or depolymerization GO:0008064 56 0.014
glycerolipid metabolic process GO:0046486 107 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.014
Fly
negative regulation of gtpase activity GO:0034260 11 0.014
forebrain neuron differentiation GO:0021879 3 0.014
internal protein amino acid acetylation GO:0006475 101 0.014
maintenance of location in cell GO:0051651 62 0.014
phospholipid metabolic process GO:0006644 99 0.014
carbohydrate derivative biosynthetic process GO:1901137 207 0.014
blastoderm segmentation GO:0007350 2 0.014
positive regulation of endocytosis GO:0045807 42 0.014
cellular response to cytokine stimulus GO:0071345 181 0.013
regulation of axonogenesis GO:0050770 16 0.013
Fly
acetylcholine secretion GO:0061526 1 0.013
single organism membrane organization GO:0044802 268 0.013
peptidyl tyrosine phosphorylation GO:0018108 170 0.013
cell division GO:0051301 168 0.013
positive regulation of transferase activity GO:0051347 227 0.013
somitogenesis GO:0001756 2 0.013
reproductive process GO:0022414 106 0.013
Worm Fly
spermatid development GO:0007286 4 0.013
glial cell migration GO:0008347 4 0.013
regulation of cell projection assembly GO:0060491 47 0.013
cell substrate adherens junction assembly GO:0007045 30 0.013
regulation of meiotic cell cycle GO:0051445 4 0.013
cellular metal ion homeostasis GO:0006875 146 0.013
response to oxidative stress GO:0006979 121 0.013
stress activated protein kinase signaling cascade GO:0031098 94 0.013
cytokinesis GO:0000910 96 0.013
modification dependent macromolecule catabolic process GO:0043632 212 0.013
regulation of cell cycle phase transition GO:1901987 126 0.013
cellular response to oxygen containing compound GO:1901701 276 0.013
regulation of non canonical wnt signaling pathway GO:2000050 4 0.013
regulation of neuron apoptotic process GO:0043523 35 0.013
spindle organization GO:0007051 53 0.013
embryonic morphogenesis GO:0048598 85 0.013
Fly
positive regulation of wound healing GO:0090303 20 0.013
regulation of neuron death GO:1901214 56 0.013
positive regulation of cell death GO:0010942 263 0.013
response to other organism GO:0051707 261 0.013
sequestering of metal ion GO:0051238 24 0.013
regulation of homeostatic process GO:0032844 121 0.013
nucleoside monophosphate metabolic process GO:0009123 191 0.013
regulation of calcium ion transport into cytosol GO:0010522 33 0.013
t cell differentiation in thymus GO:0033077 4 0.013
response to virus GO:0009615 126 0.013
negative regulation of alkaline phosphatase activity GO:0010693 2 0.013
regulation of defense response GO:0031347 154 0.013
regulation of apoptotic signaling pathway GO:2001233 175 0.013
plasma membrane organization GO:0007009 115 0.013
positive regulation of cytoskeleton organization GO:0051495 83 0.013
negative regulation of programmed cell death GO:0043069 321 0.012
meiotic chromosome segregation GO:0045132 4 0.012
cell cycle phase transition GO:0044770 173 0.012
positive regulation of growth GO:0045927 58 0.012
mitotic nuclear division GO:0007067 119 0.012
peptidyl lysine acetylation GO:0018394 101 0.012

ARHGEF11 disease predictions

Disease DO term ID Size Probability Func Analog Org
kidney disease DOID:557 36 0.051
urinary system disease DOID:18 40 0.051
cancer DOID:162 167 0.038
Human
disease of cellular proliferation DOID:14566 174 0.038
Human
sensory system disease DOID:0050155 203 0.027
nervous system disease DOID:863 431 0.027
central nervous system disease DOID:331 186 0.021
musculoskeletal system disease DOID:17 223 0.017
disease of metabolism DOID:0014667 295 0.017
retinal disease DOID:5679 118 0.016
eye and adnexa disease DOID:1492 150 0.016
eye disease DOID:5614 149 0.016
retinal degeneration DOID:8466 89 0.015
bone disease DOID:0080001 88 0.014
connective tissue disease DOID:65 109 0.014
brain disease DOID:936 73 0.013
organ system cancer DOID:0050686 164 0.013
Human