Homo sapiens

267 known processes

ARHGEF2

Rho/Rac guanine nucleotide exchange factor (GEF) 2

(Aliases: FLJ45440,DKFZp547L106,DKFZp547P1516,LFP40,GEF-H1,KIAA0651,P40,GEFH1,GEF)

ARHGEF2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of anoikis GO:2000210 4 0.820
regulation of cellular ketone metabolic process GO:0010565 50 0.580
cell fate determination GO:0001709 3 0.564
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.535
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.524
stem cell division GO:0017145 2 0.521
positive regulation of cellular component organization GO:0051130 376 0.433
protein autophosphorylation GO:0046777 123 0.415
regulation of cell differentiation GO:0045595 393 0.376
Mouse
nucleoside triphosphate metabolic process GO:0009141 422 0.363
neuroblast division GO:0055057 1 0.344
guanosine containing compound metabolic process GO:1901068 244 0.336
peptidyl serine phosphorylation GO:0018105 101 0.327
glycosyl compound catabolic process GO:1901658 413 0.326
positive regulation of cell proliferation GO:0008284 301 0.313
somatic stem cell division GO:0048103 1 0.297
cellular component morphogenesis GO:0032989 314 0.295
neuronal stem cell division GO:0036445 1 0.293
nucleotide catabolic process GO:0009166 408 0.288
asymmetric stem cell division GO:0098722 1 0.286
gtp metabolic process GO:0046039 239 0.286
purine nucleoside triphosphate catabolic process GO:0009146 392 0.284
purine containing compound catabolic process GO:0072523 411 0.280
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.280
small gtpase mediated signal transduction GO:0007264 78 0.277
Human Mouse
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.249
positive regulation of cell differentiation GO:0045597 211 0.247
gtp catabolic process GO:0006184 237 0.244
positive regulation of cell development GO:0010720 92 0.242
neuroblast proliferation GO:0007405 4 0.239
purine ribonucleoside catabolic process GO:0046130 398 0.228
regulation of cytoskeleton organization GO:0051493 177 0.224
asymmetric neuroblast division GO:0055059 1 0.224
cellular amino acid metabolic process GO:0006520 116 0.222
positive regulation of gtp catabolic process GO:0033126 166 0.217
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.212
positive regulation of cellular amine metabolic process GO:0033240 7 0.204
cell division GO:0051301 168 0.202
regulation of anatomical structure morphogenesis GO:0022603 286 0.198
Human
cell projection organization GO:0030030 252 0.190
positive regulation of neurogenesis GO:0050769 49 0.181
regulation of neuron differentiation GO:0045664 70 0.181
neuron differentiation GO:0030182 138 0.178
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.175
determination of adult lifespan GO:0008340 2 0.173
ras protein signal transduction GO:0007265 73 0.170
Mouse
cytoskeleton dependent cytokinesis GO:0061640 22 0.170
peptidyl serine modification GO:0018209 106 0.167
nucleoside triphosphate catabolic process GO:0009143 394 0.166
regulation of cell development GO:0060284 161 0.160
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 412 0.158
cellular macromolecule catabolic process GO:0044265 380 0.155
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.154
regulation of neurogenesis GO:0050767 82 0.152
Mouse
regulation of gtp catabolic process GO:0033124 180 0.149
positive regulation of catabolic process GO:0009896 310 0.148
regulation of cell morphogenesis GO:0022604 153 0.144
Human
regulation of cellular amino acid metabolic process GO:0006521 6 0.140
neuron projection development GO:0031175 106 0.137
nucleoside catabolic process GO:0009164 408 0.135
response to oxygen containing compound GO:1901700 369 0.135
amine metabolic process GO:0009308 44 0.134
cell development GO:0048468 328 0.133
Mouse
positive regulation of cellular catabolic process GO:0031331 284 0.129
regulation of cell projection organization GO:0031344 107 0.127
regulation of establishment of protein localization GO:0070201 242 0.123
axon cargo transport GO:0008088 2 0.122
regulation of neuron projection development GO:0010975 57 0.121
cytoplasmic transport GO:0016482 379 0.121
nucleoside phosphate catabolic process GO:1901292 412 0.121
microtubule based process GO:0007017 210 0.116
purine ribonucleotide catabolic process GO:0009154 404 0.114
positive regulation of nucleotide metabolic process GO:0045981 230 0.112
cell morphogenesis GO:0000902 296 0.110
regulation of ras protein signal transduction GO:0046578 155 0.109
regulation of cellular component biogenesis GO:0044087 281 0.109
purine nucleoside catabolic process GO:0006152 398 0.109
establishment of cell polarity GO:0030010 22 0.109
Mouse
regulation of nervous system development GO:0051960 88 0.109
Mouse
positive regulation of protein phosphorylation GO:0001934 313 0.108
ribonucleoside monophosphate catabolic process GO:0009158 158 0.108
ribonucleoside catabolic process GO:0042454 406 0.107
cellular protein catabolic process GO:0044257 261 0.107
protein catabolic process GO:0030163 325 0.105
ribonucleoside triphosphate catabolic process GO:0009203 391 0.105
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.104
nervous system development GO:0007399 293 0.103
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 303 0.103
lipid metabolic process GO:0006629 381 0.102
ribonucleotide catabolic process GO:0009261 405 0.100
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.095
positive regulation of nervous system development GO:0051962 54 0.095
positive regulation of programmed cell death GO:0043068 249 0.094
single organism membrane organization GO:0044802 268 0.094
positive regulation of phosphorylation GO:0042327 394 0.093
purine nucleoside triphosphate metabolic process GO:0009144 412 0.090
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.088
positive regulation of cell death GO:0010942 263 0.088
somatic stem cell maintenance GO:0035019 4 0.086
ubiquitin dependent protein catabolic process GO:0006511 206 0.085
regulation of rho gtpase activity GO:0032319 66 0.085
regulation of cell motility GO:2000145 299 0.085
positive regulation of neuron differentiation GO:0045666 40 0.085
mitotic cell cycle GO:0000278 326 0.084
Mouse
generation of neurons GO:0048699 152 0.084
Mouse
cellular ketone metabolic process GO:0042180 80 0.084
cellular response to dna damage stimulus GO:0006974 379 0.084
positive regulation of ras gtpase activity GO:0032320 117 0.082
cellular macromolecular complex assembly GO:0034622 324 0.082
cellular amine metabolic process GO:0044106 41 0.081
regulation of purine nucleotide metabolic process GO:1900542 264 0.081
cell projection morphogenesis GO:0048858 129 0.080
post embryonic development GO:0009791 2 0.079
cell adhesion GO:0007155 325 0.078
response to nitrogen compound GO:1901698 184 0.077
anoikis GO:0043276 22 0.075
protein maturation GO:0051604 233 0.073
mitotic cell cycle process GO:1903047 286 0.071
Mouse
cell cycle phase transition GO:0044770 173 0.070
response to organonitrogen compound GO:0010243 156 0.070
positive regulation of transferase activity GO:0051347 227 0.069
biological adhesion GO:0022610 331 0.069
purine nucleotide catabolic process GO:0006195 405 0.068
regulation of purine nucleotide catabolic process GO:0033121 205 0.068
regulation of kinase activity GO:0043549 314 0.067
positive regulation of cell cycle GO:0045787 140 0.067
regulation of nucleotide metabolic process GO:0006140 269 0.066
regulation of wnt signaling pathway GO:0030111 123 0.065
regulation of cellular protein catabolic process GO:1903362 96 0.064
negative regulation of locomotion GO:0040013 118 0.063
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.063
regulation of locomotion GO:0040012 329 0.062
organophosphate catabolic process GO:0046434 430 0.061
regulation of axonogenesis GO:0050770 16 0.060
negative regulation of cellular component organization GO:0051129 235 0.059
somatic muscle development GO:0007525 1 0.059
negative regulation of cell migration GO:0030336 102 0.059
cardiovascular system development GO:0072358 262 0.059
positive regulation of hydrolase activity GO:0051345 331 0.058
positive regulation of gtpase activity GO:0043547 166 0.057
cell morphogenesis involved in differentiation GO:0000904 144 0.056
axonogenesis GO:0007409 31 0.056
negative regulation of apoptotic process GO:0043066 316 0.056
regulation of proteasomal protein catabolic process GO:0061136 87 0.056
negative regulation of multicellular organismal process GO:0051241 317 0.056
Mouse
rho protein signal transduction GO:0007266 26 0.056
Mouse
positive regulation of developmental process GO:0051094 314 0.055
oogenesis GO:0048477 2 0.055
cellular response to nitrogen compound GO:1901699 144 0.055
positive regulation of nucleotide catabolic process GO:0030813 185 0.054
regulation of cellular amine metabolic process GO:0033238 11 0.054
endosomal transport GO:0016197 129 0.054
growth GO:0040007 202 0.054
regulation of cell migration GO:0030334 289 0.053
canonical wnt signaling pathway GO:0060070 116 0.053
regulation of protein transport GO:0051223 213 0.053
positive regulation of protein complex assembly GO:0031334 86 0.052
vesicle mediated transport GO:0016192 371 0.052
oocyte differentiation GO:0009994 2 0.052
response to other organism GO:0051707 261 0.051
blastoderm segmentation GO:0007350 2 0.051
single organism carbohydrate metabolic process GO:0044723 193 0.050
cellular response to oxygen containing compound GO:1901701 276 0.050
regulation of protein catabolic process GO:0042176 155 0.050
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.050
regulation of protein complex assembly GO:0043254 147 0.050
cell part morphogenesis GO:0032990 137 0.050
cellular homeostasis GO:0019725 196 0.050
microtubule cytoskeleton organization GO:0000226 176 0.049
positive regulation of apoptotic process GO:0043065 246 0.049
positive regulation of neuron projection development GO:0010976 34 0.049
regulation of proteolysis GO:0030162 293 0.049
positive regulation of protein kinase activity GO:0045860 190 0.049
oocyte development GO:0048599 1 0.049
protein targeting to nucleus GO:0044744 104 0.049
anterior posterior axis specification embryo GO:0008595 2 0.048
negative regulation of cyclin catabolic process GO:2000599 3 0.047
posttranscriptional regulation of gene expression GO:0010608 213 0.046
compound eye development GO:0048749 1 0.046
wnt signaling pathway GO:0016055 156 0.046
long term memory GO:0007616 2 0.046
negative regulation of transport GO:0051051 176 0.046
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.045
cellular lipid metabolic process GO:0044255 303 0.044
monocarboxylic acid metabolic process GO:0032787 185 0.044
regulation of cell adhesion GO:0030155 166 0.044
female gamete generation GO:0007292 2 0.044
purine ribonucleoside metabolic process GO:0046128 437 0.044
modification dependent protein catabolic process GO:0019941 209 0.044
plasma membrane organization GO:0007009 115 0.043
leukocyte activation GO:0045321 164 0.043
regulation of canonical wnt signaling pathway GO:0060828 88 0.043
retrograde transport endosome to golgi GO:0042147 45 0.043
memory GO:0007613 3 0.043
proteasomal protein catabolic process GO:0010498 176 0.042
vasculature development GO:0001944 181 0.042
multicellular organismal aging GO:0010259 3 0.042
intracellular protein transport GO:0006886 270 0.042
regulation of cell cycle process GO:0010564 266 0.042
cell substrate adhesion GO:0031589 132 0.042
activation of protein kinase activity GO:0032147 90 0.042
positive regulation of cell projection organization GO:0031346 64 0.041
positive regulation of protein catabolic process GO:0045732 75 0.041
mapk cascade GO:0000165 288 0.041
regulation of neural precursor cell proliferation GO:2000177 4 0.041
protein oligomerization GO:0051259 173 0.040
establishment or maintenance of cell polarity GO:0007163 31 0.040
Mouse
protein processing GO:0016485 226 0.040
guanosine containing compound catabolic process GO:1901069 239 0.040
cellular response to endogenous stimulus GO:0071495 336 0.040
negative regulation of wnt signaling pathway GO:0030178 69 0.040
neurogenesis GO:0022008 169 0.040
Mouse
regulation of cell cycle GO:0051726 393 0.040
positive regulation of gliogenesis GO:0014015 4 0.040
regulation of rho protein signal transduction GO:0035023 79 0.039
regulation of lipid metabolic process GO:0019216 96 0.039
response to external biotic stimulus GO:0043207 261 0.039
ribonucleotide biosynthetic process GO:0009260 81 0.039
peptidyl tyrosine phosphorylation GO:0018108 170 0.039
neuron development GO:0048666 113 0.039
protein modification by small protein conjugation GO:0032446 342 0.039
secretion GO:0046903 254 0.038
intrinsic apoptotic signaling pathway GO:0097193 127 0.038
neuromuscular junction development GO:0007528 3 0.038
atp catabolic process GO:0006200 157 0.038
atp metabolic process GO:0046034 176 0.038
regulation of epithelial cell migration GO:0010632 93 0.038
microtubule based movement GO:0007018 32 0.038
taxis GO:0042330 157 0.037
covalent chromatin modification GO:0016569 254 0.037
single organism reproductive process GO:0044702 98 0.037
neuron projection morphogenesis GO:0048812 50 0.037
signal transduction by phosphorylation GO:0023014 297 0.037
modification dependent macromolecule catabolic process GO:0043632 212 0.037
negative regulation of protein metabolic process GO:0051248 391 0.037
regulation of cell growth GO:0001558 135 0.037
regulation of cellular response to stress GO:0080135 244 0.036
positive regulation of cellular component biogenesis GO:0044089 158 0.036
microtubule polymerization or depolymerization GO:0031109 37 0.036
regulation of intracellular transport GO:0032386 195 0.036
single organism cell adhesion GO:0098602 179 0.036
regulation of cellular component movement GO:0051270 334 0.035
segmentation GO:0035282 4 0.035
regulation of protein kinase activity GO:0045859 289 0.035
nucleoside phosphate biosynthetic process GO:1901293 109 0.034
maintenance of location GO:0051235 112 0.034
protein targeting GO:0006605 187 0.034
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.034
regulation of ras gtpase activity GO:0032318 128 0.033
endomembrane system organization GO:0010256 196 0.033
negative regulation of protein phosphorylation GO:0001933 140 0.033
positive regulation of proteolysis GO:0045862 142 0.032
mitochondrion organization GO:0007005 156 0.032
regulation of growth GO:0040008 165 0.032
ameboidal type cell migration GO:0001667 135 0.032
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.032
single organism cellular localization GO:1902580 332 0.032
Mouse
negative regulation of protein maturation GO:1903318 142 0.031
positive regulation of rac gtpase activity GO:0032855 31 0.031
mitotic cell cycle phase transition GO:0044772 162 0.031
positive regulation of nucleoside metabolic process GO:0045979 186 0.031
actin filament based process GO:0030029 224 0.031
positive regulation of rho gtpase activity GO:0032321 56 0.031
negative regulation of developmental process GO:0051093 247 0.030
Mouse
positive regulation of cell adhesion GO:0045785 84 0.030
peptidyl tyrosine modification GO:0018212 170 0.030
apoptotic signaling pathway GO:0097190 268 0.030
limbic system development GO:0021761 3 0.030
nucleoside monophosphate catabolic process GO:0009125 159 0.030
regulation of nucleotide catabolic process GO:0030811 205 0.030
regulation of gtpase activity GO:0043087 180 0.030
regulation of dna metabolic process GO:0051052 153 0.029
negative regulation of cell motility GO:2000146 104 0.029
photoreceptor cell differentiation GO:0046530 2 0.029
nucleotide biosynthetic process GO:0009165 109 0.029
negative regulation of response to external stimulus GO:0032102 83 0.029
dna damage checkpoint GO:0000077 68 0.029
regulation of response to external stimulus GO:0032101 222 0.029
autophagy GO:0006914 88 0.028
response to bacterium GO:0009617 144 0.028
ribonucleoside monophosphate metabolic process GO:0009161 187 0.028
nucleoside monophosphate metabolic process GO:0009123 191 0.028
protein ubiquitination GO:0016567 314 0.028
chromatin organization GO:0006325 351 0.028
response to hormone GO:0009725 175 0.028
protein deubiquitination GO:0016579 79 0.028
response to biotic stimulus GO:0009607 276 0.028
membrane organization GO:0061024 292 0.027
protein localization to organelle GO:0033365 280 0.027
regulation of apoptotic signaling pathway GO:2001233 175 0.027
organonitrogen compound biosynthetic process GO:1901566 200 0.027
response to abiotic stimulus GO:0009628 336 0.027
regulation of tor signaling GO:0032006 30 0.027
negative regulation of cell proliferation GO:0008285 228 0.027
neurological system process GO:0050877 163 0.026
regulation of defense response GO:0031347 154 0.026
nucleocytoplasmic transport GO:0006913 176 0.026
positive regulation of immune system process GO:0002684 283 0.026
nucleus localization GO:0051647 1 0.026
negative regulation of protein modification process GO:0031400 200 0.026
cellular protein complex assembly GO:0043623 188 0.026
positive regulation of cell cycle process GO:0090068 106 0.026
cellular response to growth factor stimulus GO:0071363 197 0.025
regeneration GO:0031099 4 0.025
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.025
negative regulation of lipid metabolic process GO:0045833 38 0.025
negative regulation of cell death GO:0060548 345 0.025
negative regulation of cellular catabolic process GO:0031330 83 0.025
positive regulation of transport GO:0051050 336 0.025
purine nucleoside monophosphate metabolic process GO:0009126 186 0.025
protein localization to membrane GO:0072657 160 0.025
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.025
chromatin modification GO:0016568 298 0.025
motor neuron axon guidance GO:0008045 2 0.025
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.025
primary neural tube formation GO:0014020 3 0.025
regulation of protein serine threonine kinase activity GO:0071900 179 0.025
negative regulation of catabolic process GO:0009895 104 0.025
tissue migration GO:0090130 119 0.024
negative regulation of phosphate metabolic process GO:0045936 267 0.024
innate immune response GO:0045087 178 0.024
negative regulation of growth GO:0045926 97 0.024
regulation of homeostatic process GO:0032844 121 0.024
response to calcium ion GO:0051592 46 0.024
cellular response to peptide hormone stimulus GO:0071375 56 0.024
positive regulation of glial cell proliferation GO:0060252 2 0.024
negative regulation of protein processing GO:0010955 142 0.024
cellular component disassembly GO:0022411 92 0.024
cytokinesis GO:0000910 96 0.024
tripartite regional subdivision GO:0007351 2 0.024
chemotaxis GO:0006935 157 0.023
regulation of secretion GO:0051046 194 0.023
regulation of secretion by cell GO:1903530 177 0.023
regulation of transferase activity GO:0051338 355 0.023
axon development GO:0061564 34 0.023
astrocyte differentiation GO:0048708 4 0.023
establishment of protein localization to organelle GO:0072594 172 0.023
g2 m transition of mitotic cell cycle GO:0000086 41 0.023
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.023
nuclear transport GO:0051169 179 0.023
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.023
protein homooligomerization GO:0051260 100 0.023
cellular response to external stimulus GO:0071496 111 0.022
positive regulation of blood vessel endothelial cell migration GO:0043536 16 0.022
reactive oxygen species biosynthetic process GO:1903409 4 0.022
vesicle organization GO:0016050 62 0.022
purine nucleoside monophosphate catabolic process GO:0009128 158 0.022
regulation of nucleoside metabolic process GO:0009118 209 0.022
regulation of binding GO:0051098 111 0.022
cell projection assembly GO:0030031 126 0.022
regulation of mitotic cell cycle GO:0007346 189 0.022
microtubule bundle formation GO:0001578 15 0.022
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.022
carbohydrate metabolic process GO:0005975 207 0.022
blood vessel development GO:0001568 172 0.022
regulation of anoikis GO:2000209 19 0.021
regulation of synaptic vesicle exocytosis GO:2000300 2 0.021
tor signaling GO:0031929 39 0.021
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.021
cellular response to hormone stimulus GO:0032870 125 0.021
positive regulation of cell motility GO:2000147 177 0.021
negative regulation of cell cycle process GO:0010948 121 0.021
regulation of small gtpase mediated signal transduction GO:0051056 156 0.021
response to peptide GO:1901652 65 0.021
regulation of cytoplasmic transport GO:1903649 149 0.021
establishment of protein localization to plasma membrane GO:0090002 68 0.020
response to lipid GO:0033993 206 0.020
negative regulation of cellular protein metabolic process GO:0032269 353 0.020
cellular response to organonitrogen compound GO:0071417 124 0.020
positive regulation of mapk cascade GO:0043410 190 0.020
g1 s transition of mitotic cell cycle GO:0000082 78 0.020
positive regulation of kinase activity GO:0033674 204 0.020
response to cytokine GO:0034097 232 0.020
regulation of intracellular protein transport GO:0033157 123 0.020
regulation of protein targeting GO:1903533 91 0.020
regulation of vesicle mediated transport GO:0060627 130 0.020
cell fate commitment GO:0045165 27 0.020
blood vessel morphogenesis GO:0048514 162 0.020
rna splicing GO:0008380 131 0.020
lipid biosynthetic process GO:0008610 177 0.020
oxidation reduction process GO:0055114 396 0.019
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.019
regulation of autophagy GO:0010506 52 0.019
anatomical structure formation involved in morphogenesis GO:0048646 284 0.019
negative regulation of phosphorylation GO:0042326 174 0.019
purine nucleotide biosynthetic process GO:0006164 84 0.019
dephosphorylation GO:0016311 209 0.019
organophosphate biosynthetic process GO:0090407 163 0.019
regulation of mapk cascade GO:0043408 262 0.019
circulatory system development GO:0072359 262 0.019
i kappab kinase nf kappab signaling GO:0007249 166 0.019
muscle structure development GO:0061061 98 0.018
regulation of dephosphorylation GO:0035303 96 0.018
regulation of cell cycle phase transition GO:1901987 126 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.018
cation transport GO:0006812 331 0.018
nuclear import GO:0051170 106 0.018
macroautophagy GO:0016236 39 0.018
cell cycle g1 s phase transition GO:0044843 80 0.018
embryo development GO:0009790 123 0.018
regulation of neurotrophin trk receptor signaling pathway GO:0051386 2 0.018
neurofilament cytoskeleton organization GO:0060052 2 0.018
mrna metabolic process GO:0016071 175 0.018
peptidyl lysine modification GO:0018205 144 0.018
regulation of nucleocytoplasmic transport GO:0046822 98 0.018
negative regulation of hydrolase activity GO:0051346 182 0.017
positive regulation of mitotic cell cycle GO:0045931 60 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.017
regulation of mitotic cell cycle phase transition GO:1901990 118 0.017
stem cell differentiation GO:0048863 93 0.017
negative regulation of myotube differentiation GO:0010832 4 0.017
secretion by cell GO:0032940 226 0.017
negative regulation of cell cycle GO:0045786 193 0.017
positive regulation of cell migration GO:0030335 172 0.017
positive regulation of locomotion GO:0040017 186 0.017
locomotory behavior GO:0007626 1 0.017
endothelial cell migration GO:0043542 86 0.017
system process GO:0003008 349 0.017
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.017
cell cycle checkpoint GO:0000075 117 0.017
angiogenesis GO:0001525 147 0.017
cell growth GO:0016049 160 0.017
regulation of map kinase activity GO:0043405 108 0.017
regulation of protein localization to plasma membrane GO:1903076 40 0.016
epithelial cell migration GO:0010631 119 0.016
receptor metabolic process GO:0043112 81 0.016
dna integrity checkpoint GO:0031570 71 0.016
substrate adhesion dependent cell spreading GO:0034446 41 0.016
positive regulation of protein transport GO:0051222 135 0.016
development of primary sexual characteristics GO:0045137 35 0.016
nuclear division GO:0000280 128 0.016
ion transmembrane transport GO:0034220 338 0.016
spindle elongation GO:0051231 4 0.016
positive regulation of organelle organization GO:0010638 195 0.016
cellular response to cytokine stimulus GO:0071345 181 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
engulfment of apoptotic cell GO:0043652 2 0.016
sequestering of metal ion GO:0051238 24 0.016
pattern recognition receptor signaling pathway GO:0002221 48 0.016
mitochondrion transport along microtubule GO:0047497 3 0.016
positive regulation of autophagy GO:0010508 24 0.016
erk1 and erk2 cascade GO:0070371 104 0.016
carbohydrate derivative biosynthetic process GO:1901137 207 0.016
regulation of endocytosis GO:0030100 72 0.016
positive regulation of map kinase activity GO:0043406 80 0.016
cellular response to biotic stimulus GO:0071216 71 0.016
response to axon injury GO:0048678 1 0.016
microtubule organizing center organization GO:0031023 62 0.015
epithelial cell differentiation GO:0030855 141 0.015
negative regulation of programmed cell death GO:0043069 321 0.015
regulation of carbohydrate metabolic process GO:0006109 54 0.015
cellular response to lipid GO:0071396 127 0.015
dna replication GO:0006260 116 0.015
cell type specific apoptotic process GO:0097285 125 0.015
protein k63 linked deubiquitination GO:0070536 21 0.015
blastocyst development GO:0001824 3 0.015
regulation of chemotaxis GO:0050920 74 0.015
regulation of rna splicing GO:0043484 62 0.015
regulation of metal ion transport GO:0010959 120 0.015
inositol lipid mediated signaling GO:0048017 55 0.015
regulation of reactive oxygen species metabolic process GO:2000377 41 0.015
pattern specification process GO:0007389 43 0.015
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.015
amide transport GO:0042886 76 0.015
central nervous system development GO:0007417 123 0.015
neurotransmitter secretion GO:0007269 4 0.014
regulation of endothelial cell migration GO:0010594 67 0.014
response to lipopolysaccharide GO:0032496 70 0.014
negative regulation of catalytic activity GO:0043086 335 0.014
hemopoiesis GO:0030097 180 0.014
muscle cell differentiation GO:0042692 63 0.014
cellular response to abiotic stimulus GO:0071214 117 0.014
protein dephosphorylation GO:0006470 81 0.014
hematopoietic or lymphoid organ development GO:0048534 186 0.014
tissue regeneration GO:0042246 3 0.014
reactive oxygen species metabolic process GO:0072593 75 0.014
establishment of protein localization to membrane GO:0090150 121 0.014
neuron remodeling GO:0016322 2 0.014
negative regulation of g0 to g1 transition GO:0070317 2 0.014
cell matrix adhesion GO:0007160 85 0.014
protein localization to nucleus GO:0034504 136 0.014
translation GO:0006412 132 0.014
negative regulation of protein kinase activity GO:0006469 98 0.014
chromatin remodeling GO:0006338 55 0.014
response to acid chemical GO:0001101 66 0.014
activation of mapk activity GO:0000187 45 0.014
response to molecule of bacterial origin GO:0002237 82 0.014
muscle contraction GO:0006936 73 0.014

ARHGEF2 disease predictions

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 431 0.029
neuropathy DOID:870 52 0.029
musculoskeletal system disease DOID:17 223 0.024
disease of cellular proliferation DOID:14566 174 0.022
cancer DOID:162 167 0.017
organ system cancer DOID:0050686 164 0.017