|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.971
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.964
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.951
|
|
|
|
activation of mapkkk activity
|
GO:0000185 |
7 |
0.942
|
|
|
|
regulation of peroxidase activity
|
GO:2000468 |
2 |
0.935
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.927
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.924
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.922
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.894
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.886
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.884
|
|
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
3 |
0.880
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.876
|
|
|
|
regulation of intracellular estrogen receptor signaling pathway
|
GO:0033146 |
13 |
0.874
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.872
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.855
|
|
|
|
contact inhibition
|
GO:0060242 |
3 |
0.849
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.848
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.833
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.833
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.802
|
|
|
|
sterol import
|
GO:0035376 |
4 |
0.799
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.790
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.788
|
|
|
|
tangential migration from the subventricular zone to the olfactory bulb
|
GO:0022028 |
3 |
0.781
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.763
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.753
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
2 |
0.752
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.735
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.733
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.732
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.729
|
Rat |
|
|
regulation of kidney size
|
GO:0035564 |
2 |
0.729
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.720
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.710
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.710
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.696
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.691
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.677
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.676
|
|
|
|
positive regulation of intracellular estrogen receptor signaling pathway
|
GO:0033148 |
5 |
0.673
|
|
|
|
synaptic vesicle endocytosis
|
GO:0048488 |
2 |
0.672
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.671
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.668
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.662
|
|
|
|
negative regulation of alpha beta t cell proliferation
|
GO:0046642 |
1 |
0.660
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.641
|
|
|
|
regulation of synaptic vesicle recycling
|
GO:1903421 |
1 |
0.641
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.619
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.603
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.602
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.601
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.594
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.594
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.570
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.561
|
|
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
2 |
0.561
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.560
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.546
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.545
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.543
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.542
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.542
|
|
|
|
semaphorin plexin signaling pathway
|
GO:0071526 |
4 |
0.538
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.529
|
|
|
|
regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis
|
GO:2001270 |
3 |
0.523
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.518
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.512
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.510
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.505
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.501
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.497
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.495
|
|
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
25 |
0.487
|
|
|
|
vacuole organization
|
GO:0007033 |
44 |
0.478
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.472
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.471
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.460
|
|
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
24 |
0.455
|
|
|
|
regulation of actin filament bundle assembly
|
GO:0032231 |
36 |
0.450
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.450
|
|
|
|
sterol transmembrane transport
|
GO:0035382 |
4 |
0.448
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.445
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.442
|
|
|
|
positive regulation of stress fiber assembly
|
GO:0051496 |
22 |
0.442
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.439
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.437
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.437
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.434
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.430
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.423
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.420
|
|
|
|
positive regulation of fibroblast migration
|
GO:0010763 |
3 |
0.415
|
|
|
|
negative regulation of transforming growth factor beta1 production
|
GO:0032911 |
2 |
0.415
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.414
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.413
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.407
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.397
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.395
|
|
|
|
regulation of stress fiber assembly
|
GO:0051492 |
32 |
0.393
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.392
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.390
|
|
|
|
intracellular estrogen receptor signaling pathway
|
GO:0030520 |
23 |
0.386
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.383
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.378
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.377
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.375
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.374
|
|
|
|
cellular response to ammonium ion
|
GO:0071242 |
4 |
0.371
|
|
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
1 |
0.362
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.359
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.357
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.353
|
|
|
|
synaptic vesicle exocytosis
|
GO:0016079 |
3 |
0.352
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.351
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.349
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.343
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.343
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.342
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.340
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.338
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.332
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.332
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.327
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.320
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.318
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.316
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.314
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.311
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.310
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.310
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.309
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.309
|
|
|
|
dendritic spine morphogenesis
|
GO:0060997 |
3 |
0.305
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.304
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.294
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.291
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.290
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.289
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.283
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.271
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
35 |
0.270
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.268
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.268
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.267
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.267
|
Rat |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.266
|
|
|
|
regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033143 |
32 |
0.266
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.261
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.258
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.257
|
|
|
|
cochlea development
|
GO:0090102 |
1 |
0.257
|
|
|
|
embryonic digestive tract morphogenesis
|
GO:0048557 |
2 |
0.254
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.253
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.253
|
|
|
|
hair cell differentiation
|
GO:0035315 |
2 |
0.242
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.241
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.240
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.239
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.238
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.237
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.236
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.235
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.232
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.232
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.230
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.230
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.229
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.227
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.224
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.224
|
|
|
|
regulation of lamellipodium morphogenesis
|
GO:2000392 |
4 |
0.224
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.221
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.220
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.218
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.218
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.216
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.214
|
|
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.213
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.212
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.206
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.205
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.204
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.203
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.202
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.200
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.196
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
1 |
0.194
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.191
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.188
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.185
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.185
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.182
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.180
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.179
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.176
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.176
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.174
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.173
|
|
|
|
mitochondrion distribution
|
GO:0048311 |
3 |
0.172
|
|
|
|
lymphocyte aggregation
|
GO:0071593 |
1 |
0.172
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.170
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.168
|
|
|
|
olfactory bulb development
|
GO:0021772 |
5 |
0.167
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.166
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.166
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.164
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.160
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.159
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.156
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.156
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.155
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.154
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis
|
GO:2001271 |
3 |
0.151
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.151
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.150
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.150
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.149
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.148
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.148
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.148
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.146
|
Rat |
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.145
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.144
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.144
|
|
|
|
transforming growth factor beta1 production
|
GO:0032905 |
3 |
0.143
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.143
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.142
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.141
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.140
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.140
|
|
|
|
system process
|
GO:0003008 |
349 |
0.140
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.139
|
|
|
|
organelle inheritance
|
GO:0048308 |
2 |
0.138
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.138
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.138
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.138
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.137
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.137
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.137
|
Rat |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.133
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.132
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.130
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.130
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.128
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.127
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.126
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.124
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.123
|
|
|
|
positive regulation of synapse structural plasticity
|
GO:0051835 |
2 |
0.122
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.120
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.119
|
|
|
|
negative regulation of t cell receptor signaling pathway
|
GO:0050860 |
4 |
0.119
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.117
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.116
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.116
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.116
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.114
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
1 |
0.113
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.113
|
Fly |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.113
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.113
|
|
|
|
exit from mitosis
|
GO:0010458 |
10 |
0.112
|
|
|
|
keratinization
|
GO:0031424 |
2 |
0.112
|
|
|
|
regulation of mitochondrial membrane potential
|
GO:0051881 |
23 |
0.111
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.111
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.110
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.110
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.110
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.110
|
|
|
|
cellular response to monoamine stimulus
|
GO:0071868 |
7 |
0.110
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.109
|
|
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.108
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.108
|
|
|
|
sterol transport
|
GO:0015918 |
39 |
0.108
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.107
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.107
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.107
|
|
|
|
positive regulation of t cell tolerance induction
|
GO:0002666 |
2 |
0.106
|
|
|
|
negative regulation of transforming growth factor beta production
|
GO:0071635 |
4 |
0.106
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.104
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.103
|
|
|
|
regulation of cell cell adhesion mediated by cadherin
|
GO:2000047 |
4 |
0.103
|
|
|
|
dopamine receptor signaling pathway
|
GO:0007212 |
10 |
0.102
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.102
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.102
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.101
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
3 |
0.100
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.099
|
|
|
|
telencephalon development
|
GO:0021537 |
17 |
0.099
|
|
|
|
dendritic spine development
|
GO:0060996 |
6 |
0.098
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.098
|
|
|
|
regulation of dendrite morphogenesis
|
GO:0048814 |
11 |
0.097
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.097
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.096
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.095
|
|
|
|
focal adhesion assembly
|
GO:0048041 |
30 |
0.094
|
|
|
|
maintenance of cell polarity
|
GO:0030011 |
2 |
0.094
|
|
|
|
regulation of execution phase of apoptosis
|
GO:1900117 |
11 |
0.094
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.094
|
|
|
|
negative regulation of hydrogen peroxide induced cell death
|
GO:1903206 |
9 |
0.093
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.093
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.093
|
|
|
|
neuroblast division
|
GO:0055057 |
1 |
0.091
|
|
|
|
establishment of spindle orientation
|
GO:0051294 |
9 |
0.091
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.089
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.089
|
|
|
|
negative regulation of execution phase of apoptosis
|
GO:1900118 |
6 |
0.088
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.088
|
|
|
|
regulation of membrane depolarization
|
GO:0003254 |
19 |
0.088
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.087
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.087
|
|
|
|
negative regulation of interleukin 23 production
|
GO:0032707 |
1 |
0.087
|
|
|
|
astrocyte cell migration
|
GO:0043615 |
1 |
0.087
|
Rat |
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.086
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.086
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.083
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.083
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.083
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.083
|
|
|
|
synaptic vesicle recycling
|
GO:0036465 |
3 |
0.082
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.082
|
|
|
|
head development
|
GO:0060322 |
108 |
0.081
|
|
|
|
regulation of oxidative stress induced cell death
|
GO:1903201 |
24 |
0.081
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.080
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.079
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.079
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.078
|
|
|
|
gonad development
|
GO:0008406 |
34 |
0.077
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.077
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.077
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.077
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.076
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
23 |
0.075
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.075
|
|
|
|
spindle localization
|
GO:0051653 |
12 |
0.074
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.074
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.074
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.074
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.072
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.071
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.071
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.071
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.070
|
|
|
|
fibroblast migration
|
GO:0010761 |
7 |
0.070
|
|
|
|
regulation of neuroblast proliferation
|
GO:1902692 |
3 |
0.070
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.069
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.069
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.069
|
|
|
|
tachykinin receptor signaling pathway
|
GO:0007217 |
3 |
0.068
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.068
|
|
|
|
establishment of monopolar cell polarity
|
GO:0061162 |
1 |
0.066
|
|
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.066
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.066
|
|
|
|
ribonucleoprotein complex assembly
|
GO:0022618 |
78 |
0.066
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.065
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.065
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.064
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.064
|
|
|
|
execution phase of apoptosis
|
GO:0097194 |
32 |
0.064
|
|
|
|
regulation of transforming growth factor beta1 production
|
GO:0032908 |
3 |
0.064
|
|
|
|
establishment or maintenance of monopolar cell polarity
|
GO:0061339 |
1 |
0.063
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.063
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.062
|
|
|
|
memory
|
GO:0007613 |
3 |
0.062
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.061
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.061
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.061
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.061
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.060
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.060
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.059
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.059
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.059
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.058
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.058
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.058
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.056
|
|
|
|
regulation of arf protein signal transduction
|
GO:0032012 |
1 |
0.056
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.056
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.055
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.055
|
|
|
|
ribonucleoprotein complex subunit organization
|
GO:0071826 |
81 |
0.054
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.054
|
|
|
|
myoblast proliferation
|
GO:0051450 |
1 |
0.054
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.054
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.053
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.053
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.053
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.053
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.053
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.052
|
|
|
|
response to manganese ion
|
GO:0010042 |
2 |
0.052
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.051
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.051
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.051
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.051
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
32 |
0.050
|
|
|
|
growth
|
GO:0040007 |
202 |
0.050
|
|
|
|
regulation of t cell tolerance induction
|
GO:0002664 |
4 |
0.050
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.049
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
39 |
0.049
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.049
|
|
|
|
attachment of spindle microtubules to kinetochore
|
GO:0008608 |
17 |
0.048
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.048
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.048
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.047
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.047
|
|
|
|
protein autoubiquitination
|
GO:0051865 |
37 |
0.047
|
|
|
|
establishment of mitotic spindle orientation
|
GO:0000132 |
7 |
0.046
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.046
|
|
|
|
negative regulation of response to oxidative stress
|
GO:1902883 |
18 |
0.046
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.046
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.046
|
|
|
|
establishment or maintenance of neuroblast polarity
|
GO:0045196 |
1 |
0.045
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.045
|
|
|
|
positive regulation of metalloenzyme activity
|
GO:0048554 |
2 |
0.045
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.045
|
|
|
|
negative regulation of striated muscle contraction
|
GO:0045988 |
2 |
0.044
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.044
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.044
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.044
|
|
|
|
ectodermal placode development
|
GO:0071696 |
1 |
0.044
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.044
|
|
|
|
response to monoamine
|
GO:0071867 |
7 |
0.044
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.043
|
|
|
|
regulation of cell maturation
|
GO:1903429 |
3 |
0.043
|
|
|
|
regulation of hydrogen peroxide induced cell death
|
GO:1903205 |
10 |
0.043
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.043
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.043
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.043
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.043
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.043
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
1 |
0.042
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.042
|
|
|
|
negative regulation of oxidative stress induced cell death
|
GO:1903202 |
17 |
0.042
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.042
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.042
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.042
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
23 |
0.041
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
26 |
0.041
|
|
|
|
neuron projection extension
|
GO:1990138 |
14 |
0.041
|
|
|
|
negative regulation of cellular response to oxidative stress
|
GO:1900408 |
18 |
0.041
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
23 |
0.041
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.041
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.041
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.041
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.040
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.040
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.040
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.040
|
|
|
|
positive regulation of g protein coupled receptor protein signaling pathway
|
GO:0045745 |
9 |
0.040
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.039
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.039
|
|
|
|
hemidesmosome assembly
|
GO:0031581 |
5 |
0.039
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.039
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.039
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.039
|
|
|
|
arf protein signal transduction
|
GO:0032011 |
0 |
0.039
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
37 |
0.038
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.038
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.038
|
|
|
|
positive regulation of autophagy
|
GO:0010508 |
24 |
0.038
|
|
|
|
positive regulation of protein autoubiquitination
|
GO:1902499 |
2 |
0.038
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.038
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.038
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.037
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.037
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.037
|
|
|
|
negative regulation of nucleotide metabolic process
|
GO:0045980 |
29 |
0.037
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.036
|
|
|
|
dendritic spine organization
|
GO:0097061 |
4 |
0.036
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.036
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.036
|
|
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
5 |
0.035
|
|
|
|
cellular response to catecholamine stimulus
|
GO:0071870 |
7 |
0.035
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.035
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.035
|
|
|
|
regulation of response to oxidative stress
|
GO:1902882 |
26 |
0.035
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.035
|
|
|
|
establishment of mitotic spindle localization
|
GO:0040001 |
8 |
0.034
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.034
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.034
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.034
|
|
|
|
thymus development
|
GO:0048538 |
3 |
0.034
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
37 |
0.033
|
|
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
37 |
0.033
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.033
|
|
