|
|
positive regulation of hormone biosynthetic process
|
GO:0046886 |
4 |
0.989
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia
|
GO:0061419 |
2 |
0.961
|
|
|
|
specification of organ identity
|
GO:0010092 |
3 |
0.834
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
4 |
0.731
|
|
|
|
axon cargo transport
|
GO:0008088 |
2 |
0.725
|
|
|
|
mating
|
GO:0007618 |
1 |
0.670
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.478
|
|
|
|
response to xenobiotic stimulus
|
GO:0009410 |
30 |
0.453
|
Zebrafish Worm |
|
|
regulation of transcription from rna polymerase ii promoter in response to oxidative stress
|
GO:0043619 |
5 |
0.396
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.377
|
|
|
|
rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0051123 |
4 |
0.346
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.340
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.336
|
Fly |
|
|
patterning of blood vessels
|
GO:0001569 |
2 |
0.326
|
|
|
|
blood vessel remodeling
|
GO:0001974 |
2 |
0.317
|
|
|
|
memory
|
GO:0007613 |
3 |
0.304
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.298
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.285
|
|
|
|
transforming growth factor beta production
|
GO:0071604 |
14 |
0.282
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.281
|
Fly |
|
|
organ formation
|
GO:0048645 |
3 |
0.272
|
|
|
|
hormone metabolic process
|
GO:0042445 |
61 |
0.265
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.247
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.232
|
Worm |
|
|
gas homeostasis
|
GO:0033483 |
4 |
0.230
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.227
|
|
|
|
cardiac ventricle development
|
GO:0003231 |
23 |
0.226
|
|
|
|
oxygen homeostasis
|
GO:0032364 |
4 |
0.221
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.215
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.209
|
|
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.196
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.193
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.193
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.190
|
Mouse |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.186
|
|
|
|
regulation of receptor biosynthetic process
|
GO:0010869 |
15 |
0.183
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.183
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.182
|
Fly |
|
|
regulation of system process
|
GO:0044057 |
101 |
0.178
|
|
|
|
regulation of growth rate
|
GO:0040009 |
1 |
0.174
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.170
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.170
|
Fly |
|
|
regulation of oxidative stress induced cell death
|
GO:1903201 |
24 |
0.168
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.167
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.166
|
Fly |
|
|
cellular response to camp
|
GO:0071320 |
21 |
0.161
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.155
|
Fly |
|
|
immune system development
|
GO:0002520 |
195 |
0.155
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.150
|
Mouse |
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.144
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.142
|
|
|
|
response to nitric oxide
|
GO:0071731 |
4 |
0.136
|
|
|
|
dna templated transcription initiation
|
GO:0006352 |
35 |
0.134
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.132
|
Fly |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.132
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.131
|
Fly |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.130
|
|
|
|
response to auditory stimulus
|
GO:0010996 |
4 |
0.129
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.129
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.129
|
|
|
|
transcription initiation from rna polymerase ii promoter
|
GO:0006367 |
27 |
0.128
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.127
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.125
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.124
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.124
|
|
|
|
response to activity
|
GO:0014823 |
0 |
0.120
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.119
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.119
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.118
|
|
|
|
protein dna complex assembly
|
GO:0065004 |
64 |
0.117
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.115
|
Fly |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.114
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.114
|
Fly |
|
|
regulation of hormone metabolic process
|
GO:0032350 |
14 |
0.113
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.113
|
Fly |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.110
|
|
|
|
positive regulation of autophagy
|
GO:0010508 |
24 |
0.110
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.109
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to hypoxia
|
GO:0061418 |
7 |
0.106
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.106
|
Fly |
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.104
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.102
|
|
|
|
negative regulation of blood pressure
|
GO:0045776 |
3 |
0.101
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.101
|
Fly |
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
21 |
0.101
|
|
|
|
b cell homeostasis
|
GO:0001782 |
1 |
0.098
|
|
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
4 |
0.097
|
|
|
|
regulation of heart rate
|
GO:0002027 |
38 |
0.096
|
|
|
|
retina vasculature development in camera type eye
|
GO:0061298 |
3 |
0.094
|
|
|
|
heat acclimation
|
GO:0010286 |
3 |
0.094
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.094
|
|
|
|
kidney morphogenesis
|
GO:0060993 |
19 |
0.094
|
|
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
26 |
0.094
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.092
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.092
|
|
|
|
nephron development
|
GO:0072006 |
30 |
0.092
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.091
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.088
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.087
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.087
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.086
|
Fly |
|
|
sensory perception of light stimulus
|
GO:0050953 |
35 |
0.086
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.085
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.085
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.084
|
|
|
|
transforming growth factor beta2 production
|
GO:0032906 |
6 |
0.083
|
|
|
|
response to camp
|
GO:0051591 |
25 |
0.083
|
|
|
|
venous blood vessel development
|
GO:0060841 |
2 |
0.082
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.082
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.082
|
Fly |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.082
|
|
|
|
lung development
|
GO:0030324 |
20 |
0.081
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.079
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.079
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.079
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.079
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.079
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.078
|
Fly |
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.078
|
|
|
|
t cell homeostasis
|
GO:0043029 |
3 |
0.078
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.078
|
|
|
|
protein dna complex subunit organization
|
GO:0071824 |
80 |
0.078
|
|
|
|
cardiac chamber development
|
GO:0003205 |
30 |
0.077
|
|
|
|
microtubule based movement
|
GO:0007018 |
32 |
0.077
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.076
|
|
|
|
neuron death in response to oxidative stress
|
GO:0036475 |
9 |
0.076
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.076
|
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
29 |
0.076
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
72 |
0.075
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
30 |
0.075
|
|
|
|
regulation of oxidative stress induced neuron death
|
GO:1903203 |
9 |
0.075
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.074
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.074
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.073
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.073
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.073
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.072
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.072
|
|
|
|
cardiac ventricle morphogenesis
|
GO:0003208 |
20 |
0.071
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.069
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.068
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.068
|
Fly |
|
|
vasculature development
|
GO:0001944 |
181 |
0.067
|
|
|
|
receptor biosynthetic process
|
GO:0032800 |
18 |
0.067
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.067
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.066
|
Fly |
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.066
|
|
|
|
negative regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060633 |
3 |
0.066
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.066
|
|
|
|
positive regulation of hormone metabolic process
|
GO:0032352 |
6 |
0.065
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.065
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.064
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.064
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.064
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.064
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.063
|
Human Worm Fly |
|
|
protein maturation
|
GO:0051604 |
233 |
0.063
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.063
|
|
|
|
growth
|
GO:0040007 |
202 |
0.062
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.062
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.062
|
|
|
|
system process
|
GO:0003008 |
349 |
0.062
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.061
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
26 |
0.061
|
|
|
|
axon transport of mitochondrion
|
GO:0019896 |
2 |
0.061
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.060
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.059
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.059
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.059
|
|
|
|
norepinephrine metabolic process
|
GO:0042415 |
1 |
0.059
|
|
|
|
chemical homeostasis within a tissue
|
GO:0048875 |
3 |
0.059
|
|
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
64 |
0.059
|
|
|
|
positive regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060261 |
4 |
0.058
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.058
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.058
|
|
|
|
negative regulation of oxidative stress induced cell death
|
GO:1903202 |
17 |
0.057
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.057
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.056
|
|
|
|
positive regulation vascular endothelial growth factor production
|
GO:0010575 |
12 |
0.056
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.056
|
|
|
|
iron ion homeostasis
|
GO:0055072 |
15 |
0.056
|
|
|
|
regulation of response to oxidative stress
|
GO:1902882 |
26 |
0.055
|
|
|
|
regulation of tube size
|
GO:0035150 |
18 |
0.055
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.055
|
|
|
|
cytoskeleton dependent intracellular transport
|
GO:0030705 |
21 |
0.055
|
|
|
|
surfactant homeostasis
|
GO:0043129 |
3 |
0.054
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.053
|
|
|
|
negative regulation of cellular response to oxidative stress
|
GO:1900408 |
18 |
0.053
|
|
|
|
neuron intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0036480 |
7 |
0.053
|
|
|
|
necrotic cell death
|
GO:0070265 |
21 |
0.053
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.053
|
Mouse |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.053
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.052
|
Mouse |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.052
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.051
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.051
|
Worm Fly |
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.051
|
|
|
|
regulation of transforming growth factor beta production
|
GO:0071634 |
13 |
0.051
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.050
|
|
|
|
prostate gland development
|
GO:0030850 |
3 |
0.050
|
|
|
|
regulation of rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0045898 |
3 |
0.050
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.050
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.050
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.049
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.049
|
|
|
|
post embryonic hemopoiesis
|
GO:0035166 |
1 |
0.049
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.048
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.048
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.048
|
Mouse |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.048
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.048
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.047
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.047
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.047
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.046
|
|
|
|
negative regulation of response to oxidative stress
|
GO:1902883 |
18 |
0.046
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.046
|
|
|
|
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway
|
GO:1903376 |
7 |
0.046
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.045
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.045
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.045
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.045
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.045
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.045
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.045
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.044
|
|
|
|
trachea development
|
GO:0060438 |
1 |
0.044
|
|
|
|
negative regulation of systemic arterial blood pressure
|
GO:0003085 |
1 |
0.044
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.044
|
Fly |
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
17 |
0.044
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.044
|
|
|
|
tissue remodeling
|
GO:0048771 |
16 |
0.043
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.043
|
|
|
|
visual perception
|
GO:0007601 |
27 |
0.043
|
|
|
|
transition metal ion homeostasis
|
GO:0055076 |
31 |
0.043
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.042
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.042
|
Fly |
|
|
hemoglobin metabolic process
|
GO:0020027 |
3 |
0.042
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.042
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.042
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.042
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
10 |
0.041
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.041
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.041
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.041
|
Fly |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.041
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.040
|
Fly |
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
19 |
0.040
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.040
|
|
|
|
microtubule based transport
|
GO:0010970 |
21 |
0.040
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.040
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.040
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.039
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.039
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.039
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.039
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.039
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.039
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.038
|
|
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
37 |
0.038
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.038
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.038
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.038
|
Mouse |
|
|
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902176 |
10 |
0.038
|
|
|
|
trabecula morphogenesis
|
GO:0061383 |
2 |
0.038
|
|
|
|
negative regulation of blood circulation
|
GO:1903523 |
4 |
0.038
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.037
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.037
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.037
|
Fly |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.037
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.037
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.037
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.037
|
|
|
|
myoblast differentiation
|
GO:0045445 |
21 |
0.036
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.036
|
|
|
|
protein hydroxylation
|
GO:0018126 |
9 |
0.036
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.035
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.035
|
|
|
|
regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902175 |
16 |
0.035
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.035
|
|
|
|
hormone biosynthetic process
|
GO:0042446 |
22 |
0.035
|
|
|
|
regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060260 |
8 |
0.035
|
|
|
|
tissue homeostasis
|
GO:0001894 |
63 |
0.035
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.034
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.034
|
|
|
|
spleen development
|
GO:0048536 |
1 |
0.034
|
|
|
|
aging
|
GO:0007568 |
66 |
0.034
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.034
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.034
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.033
|
|
|
|
smooth muscle tissue development
|
GO:0048745 |
3 |
0.033
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.033
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
29 |
0.033
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.032
|
|
|
|
cellular response to interleukin 1
|
GO:0071347 |
35 |
0.032
|
|
|
|
cardiac muscle adaptation
|
GO:0014887 |
4 |
0.032
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.032
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.032
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.032
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.032
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.032
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.031
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.031
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.031
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.031
|
Human Fly |
|
|
camp metabolic process
|
GO:0046058 |
61 |
0.030
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.030
|
|
|
|
positive regulation of receptor biosynthetic process
|
GO:0010870 |
8 |
0.030
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.030
|
Mouse Fly |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.030
|
|
|
|
ovulation cycle process
|
GO:0022602 |
9 |
0.030
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.030
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.030
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.030
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
40 |
0.029
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.029
|
|
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.029
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.029
|
|
|
|
regulation of hormone biosynthetic process
|
GO:0046885 |
10 |
0.029
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.029
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
24 |
0.029
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.028
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.028
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.028
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.028
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.028
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.028
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.028
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.028
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.028
|
Fly |
|
|
response to estradiol
|
GO:0032355 |
23 |
0.028
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.027
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.027
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.027
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.027
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.027
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.027
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.027
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.027
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.026
|
|
|
|
female gonad development
|
GO:0008585 |
10 |
0.026
|
|
|
|
b cell proliferation
|
GO:0042100 |
22 |
0.026
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.026
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.026
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.026
|
Fly |
|
|
ventricular septum morphogenesis
|
GO:0060412 |
3 |
0.026
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.026
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.025
|
|
|
|
regulation of dna templated transcription initiation
|
GO:2000142 |
9 |
0.025
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.025
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.025
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.025
|
|
|
|
vascular endothelial growth factor production
|
GO:0010573 |
15 |
0.025
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.025
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.025
|
Mouse Fly |
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.025
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
4 |
0.025
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.025
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.025
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.025
|
Fly |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.025
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.025
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.025
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.024
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.024
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.024
|
Fly |
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.024
|
|
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
18 |
0.024
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.024
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.024
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.024
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
9 |
0.024
|
|
|
|
regulation of heart growth
|
GO:0060420 |
4 |
0.024
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.024
|
|
|
|
negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway
|
GO:1903377 |
5 |
0.024
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.023
|
|
|
|
response to interleukin 1
|
GO:0070555 |
47 |
0.023
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.023
|
Mouse Fly |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.023
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.023
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.023
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.023
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.023
|
Fly |
|
|
limbic system development
|
GO:0021761 |
3 |
0.023
|
|
|
|
regulation of transforming growth factor beta2 production
|
GO:0032909 |
6 |
0.023
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.023
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.023
|
|
|
|
myoblast fate commitment
|
GO:0048625 |
1 |
0.022
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.022
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.022
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.022
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.022
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.022
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.022
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.022
|
|
|
|
oxidative stress induced premature senescence
|
GO:0090403 |
3 |
0.022
|
|
|
|
regulation of vascular endothelial growth factor production
|
GO:0010574 |
13 |
0.021
|
|
|
|
ovulation cycle
|
GO:0042698 |
9 |
0.021
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.021
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.021
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.021
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.021
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.021
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.021
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.021
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.021
|
Fly |
|
|
epithelium migration
|
GO:0090132 |
119 |
0.021
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.021
|
Fly |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.021
|
|
|
|
thymocyte apoptotic process
|
GO:0070242 |
2 |
0.021
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.020
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.020
|
|
|
|
respiratory system development
|
GO:0060541 |
22 |
0.020
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.020
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.020
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.020
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.020
|
Mouse |
|
|
regulation of necrotic cell death
|
GO:0010939 |
9 |
0.020
|
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.020
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.020
|
|
|
|
trophectodermal cell differentiation
|
GO:0001829 |
3 |
0.020
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.020
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
47 |
0.020
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.020
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.020
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.020
|
|
|
|
cell proliferation in forebrain
|
GO:0021846 |
1 |
0.020
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.019
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.019
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.019
|
|
|
|
response to toxic substance
|
GO:0009636 |
37 |
0.019
|
Zebrafish |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.019
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.019
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.019
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.019
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.019
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.019
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.019
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.019
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.019
|
|
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.019
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.019
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.019
|
|
|
|
neural crest cell migration
|
GO:0001755 |
2 |
0.019
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.019
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.019
|
|
|
|
regulation of vasoconstriction
|
GO:0019229 |
5 |
0.018
|
|
|
|
cellular response to toxic substance
|
GO:0097237 |
4 |
0.018
|
|
|
|
rhythmic process
|
GO:0048511 |
31 |
0.018
|
Human |
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.018
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.018
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.018
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.018
|
Fly |
|
|
muscle cell cellular homeostasis
|
GO:0046716 |
3 |
0.018
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.018
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.018
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.018
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.018
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.018
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.018
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.018
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.018
|
Fly |
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.018
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.017
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.017
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.017
|
Fly |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.017
|
Fly |
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.017
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.017
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.017
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.017
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.017
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.017
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.017
|
Fly |
|
|
cognition
|
GO:0050890 |
43 |
0.017
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.017
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.017
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.017
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.017
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.017
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.017
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.017
|
|
|
|
atrioventricular valve development
|
GO:0003171 |
3 |
0.017
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.017
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.017
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.016
|
|
