|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.996
|
Human |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.995
|
Human Rat |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.993
|
Human Rat |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.990
|
Human Rat |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.986
|
Human Rat |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.986
|
Human |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.980
|
Human Rat |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.976
|
Human Rat |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.969
|
Human Rat |
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.959
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.959
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.956
|
Human Rat |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.954
|
Human |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.951
|
Human |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.950
|
Rat |
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.902
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.893
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.880
|
Human |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.879
|
Human Rat |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.879
|
Human Rat |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.866
|
Human Rat |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.852
|
Human Rat |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.842
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.842
|
Human Rat |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.834
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.828
|
Human Rat |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.822
|
Human Rat |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.819
|
|
|
|
receptor internalization
|
GO:0031623 |
43 |
0.812
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.811
|
|
|
|
positive regulation of rho protein signal transduction
|
GO:0035025 |
4 |
0.798
|
Human |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.794
|
Human Rat |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.769
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.768
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.767
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.767
|
Human |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.733
|
Human Rat |
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.722
|
Rat |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.719
|
Human Rat |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.714
|
Human |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.711
|
Rat |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.707
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.700
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.697
|
Rat |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.679
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.676
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.673
|
Human Rat |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.662
|
|
|
|
growth
|
GO:0040007 |
202 |
0.661
|
Worm |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.639
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.638
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.636
|
Human |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.628
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.623
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.616
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.607
|
|
|
|
hyperosmotic response
|
GO:0006972 |
4 |
0.589
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.584
|
Human |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.584
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.584
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.583
|
Rat |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.582
|
Rat |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.577
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.576
|
Rat |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.555
|
Human Rat |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.553
|
Human Rat |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.551
|
|
|
|
organelle inheritance
|
GO:0048308 |
2 |
0.544
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.540
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.535
|
Rat |
|
|
blood circulation
|
GO:0008015 |
113 |
0.535
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.531
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.530
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.530
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.525
|
Rat |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.523
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.522
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.515
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.513
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.486
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.484
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.481
|
Human |
|
|
synaptic vesicle endocytosis
|
GO:0048488 |
2 |
0.470
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.463
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.457
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.456
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.451
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.450
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.448
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.447
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.445
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.442
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.437
|
|
|
|
system process
|
GO:0003008 |
349 |
0.437
|
Rat |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.434
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.432
|
Rat |
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.423
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.421
|
Rat |
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.421
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.420
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.408
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.402
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.402
|
Human Rat |
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.401
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.398
|
Human Rat |
|
|
secretion by cell
|
GO:0032940 |
226 |
0.388
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.382
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.382
|
Rat |
|
|
homotypic cell cell adhesion
|
GO:0034109 |
47 |
0.380
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.379
|
Human Rat |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.375
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.373
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.371
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.370
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.364
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.364
|
Human |
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.364
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.359
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.354
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.352
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.350
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.347
|
Rat |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.339
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.336
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.332
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.331
|
Rat |
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.331
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.327
|
Human |
|
|
endocytosis
|
GO:0006897 |
159 |
0.327
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.326
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.321
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.319
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.318
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.317
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.315
|
Human Rat |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.314
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.312
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.311
|
Human |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.306
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.304
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.303
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.300
|
Human |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.298
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.298
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.297
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.295
|
Human |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.294
|
Rat |
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.292
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.289
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.289
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.289
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.287
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.287
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.287
|
Human Rat |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.278
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.276
|
Human Mouse |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.274
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.272
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.271
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.270
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.269
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.268
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.266
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.266
|
Human |
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.265
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.265
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.264
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.264
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.264
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.262
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.262
|
|
|
|
phototransduction
|
GO:0007602 |
3 |
0.256
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.255
|
Human Rat |
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.252
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.251
|
Human |
|
|
synaptic vesicle exocytosis
|
GO:0016079 |
3 |
0.250
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.249
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.248
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.246
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.246
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.244
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.244
|
Human |
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.242
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.242
|
Rat |
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.238
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.236
|
Rat |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.236
|
Human |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.234
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.230
|
Human |
|
|
heart process
|
GO:0003015 |
62 |
0.230
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.229
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.229
|
Rat |
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.228
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.226
|
Human |
|
|
cgmp catabolic process
|
GO:0046069 |
3 |
0.225
|
|
|
|
negative regulation of insulin secretion involved in cellular response to glucose stimulus
|
GO:0061179 |
1 |
0.221
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.217
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.213
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.212
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.210
|
Worm |
|
|
cellular response to heat
|
GO:0034605 |
14 |
0.208
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.208
|
Human |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.207
|
|
|
|
regulation of histone acetylation
|
GO:0035065 |
19 |
0.203
|
Human |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.202
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
5 |
0.198
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.197
|
Human |
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.197
|
|
|
|
late endosome to vacuole transport
|
GO:0045324 |
2 |
0.195
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
33 |
0.195
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.191
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.191
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.190
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.190
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.188
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.186
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.184
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.184
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.183
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.183
|
|
|
|
regulation of growth rate
|
GO:0040009 |
1 |
0.182
|
Worm |
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.180
|
Rat |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.178
|
Human Rat |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.178
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.177
|
|
|
|
aging
|
GO:0007568 |
66 |
0.177
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
4 |
0.175
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.174
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.172
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.168
|
|
|
|
negative regulation of jnk cascade
|
GO:0046329 |
16 |
0.166
|
|
|
|
regulation of natural killer cell mediated cytotoxicity
|
GO:0042269 |
16 |
0.166
|
|
|
|
synaptic vesicle transport
|
GO:0048489 |
5 |
0.165
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.163
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.163
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.162
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.160
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.159
|
Rat |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.158
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.158
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.155
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.154
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.151
|
Rat |
|
|
establishment of vesicle localization
|
GO:0051650 |
23 |
0.151
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.149
|
|
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.149
|
Rat |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.148
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.147
|
Rat |
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.146
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.145
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.144
|
Rat |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.142
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.141
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.141
|
|
|
|
positive regulation of receptor internalization
|
GO:0002092 |
12 |
0.141
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.140
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.139
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.137
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.137
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.137
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.136
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.136
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.136
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.135
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.135
|
Rat |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.134
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.132
|
Human |
|
|
regulation of system process
|
GO:0044057 |
101 |
0.132
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.132
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.129
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.125
|
Human |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.121
|
|
|
|
jun phosphorylation
|
GO:0007258 |
28 |
0.120
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.119
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.119
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.118
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.117
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.116
|
Human Rat |
|
|
regulation of interleukin 6 production
|
GO:0032675 |
37 |
0.114
|
Human Mouse |
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.112
|
Human |
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.112
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.111
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.110
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.109
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.109
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.109
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.108
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
45 |
0.108
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.107
|
Mouse |
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.107
|
Human |
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.107
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.106
|
Rat |
|
|
golgi vesicle transport
|
GO:0048193 |
80 |
0.106
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.106
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.105
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.105
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.105
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.105
|
|
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.104
|
Human |
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.104
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
41 |
0.103
|
|
|
|
desensitization of g protein coupled receptor protein signaling pathway by arrestin
|
GO:0002032 |
2 |
0.103
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.103
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.102
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.102
|
Rat |
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.101
|
Human |
|
|
vacuole organization
|
GO:0007033 |
44 |
0.101
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.100
|
|
|
|
adaptation of signaling pathway
|
GO:0023058 |
7 |
0.100
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.099
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.098
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.098
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.098
|
|
|
|
protein complex disassembly
|
GO:0043241 |
52 |
0.098
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.098
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.098
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.097
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.096
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.095
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.095
|
Zebrafish |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.095
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.095
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.095
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.095
|
Human |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.095
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.094
|
Human Rat |
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.094
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.093
|
|
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
3 |
0.093
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.093
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.091
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.090
|
Human |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.090
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.090
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.090
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.089
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.088
|
Rat |
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.088
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.086
|
|
|
|
collateral sprouting
|
GO:0048668 |
2 |
0.086
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.086
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.086
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.086
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.085
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.084
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.084
|
|
|
|
glucose homeostasis
|
GO:0042593 |
31 |
0.083
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.083
|
Mouse |
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.083
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.082
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.081
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.081
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.080
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.080
|
Rat |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.080
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.079
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.079
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.079
|
Human |
|
|
organelle assembly
|
GO:0070925 |
176 |
0.078
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.078
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.077
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.077
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.077
|
|
|
|
regulation of release of sequestered calcium ion into cytosol
|
GO:0051279 |
27 |
0.077
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.077
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.076
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.076
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.075
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.075
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.075
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.074
|
|
|
|
glomerular mesangial cell development
|
GO:0072144 |
1 |
0.074
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.074
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.074
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.073
|
Mouse |
|
|
synaptic vesicle recycling
|
GO:0036465 |
3 |
0.073
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.073
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.073
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.073
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.073
|
Rat |
|
|
activation of immune response
|
GO:0002253 |
114 |
0.072
|
Mouse |
|
|
positive regulation of chromatin modification
|
GO:1903310 |
30 |
0.071
|
Human |
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.071
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
15 |
0.070
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.070
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.070
|
|
|
|
cellular response to vascular endothelial growth factor stimulus
|
GO:0035924 |
26 |
0.069
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.069
|
Rat |
|
|
embryo development
|
GO:0009790 |
123 |
0.069
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.069
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.068
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.067
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.067
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.067
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.067
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.067
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.067
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.067
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.067
|
|
|
|
cilium assembly
|
GO:0042384 |
63 |
0.067
|
|
|
|
mrna processing
|
GO:0006397 |
133 |
0.066
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.066
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.066
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.066
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.066
|
Rat |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.065
|
|
|
|
post golgi vesicle mediated transport
|
GO:0006892 |
36 |
0.065
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.065
|
Rat |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.065
|
Zebrafish |
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.065
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.065
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.064
|
|
|
|
regulation of endosome size
|
GO:0051036 |
3 |
0.064
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
22 |
0.063
|
Rat |
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.063
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.063
|
Human Mouse |
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.063
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.063
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.063
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.062
|
Rat |
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.062
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.061
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.061
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.061
|
|
|
|
cilium organization
|
GO:0044782 |
68 |
0.061
|
|
|
|
negative regulation of small gtpase mediated signal transduction
|
GO:0051058 |
12 |
0.061
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.060
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.060
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.059
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.059
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.058
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.058
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.057
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.057
|
Rat |
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.057
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.057
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.057
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.057
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.056
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.056
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
38 |
0.056
|
|
|
|
embryonic digestive tract morphogenesis
|
GO:0048557 |
2 |
0.056
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.055
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.055
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.055
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.055
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.054
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.053
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.053
|
Human Mouse |
|
|
cation transport
|
GO:0006812 |
331 |
0.052
|
Rat |
|
|
regulation of actin filament depolymerization
|
GO:0030834 |
10 |
0.052
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.052
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.052
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.051
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.051
|
Mouse |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.051
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.051
|
Mouse |
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.051
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.051
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.051
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.050
|
|
|
|
platelet activation
|
GO:0030168 |
44 |
0.050
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.050
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.050
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.050
|
Zebrafish |
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.048
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.048
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.048
|
|
|
|
cellular response to carbohydrate stimulus
|
GO:0071322 |
11 |
0.048
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.048
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.048
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
60 |
0.047
|
|
|
|
translation
|
GO:0006412 |
132 |
0.047
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.047
|
Mouse |
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
33 |
0.047
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
38 |
0.047
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.047
|
|
|
|
granulocyte migration
|
GO:0097530 |
40 |
0.046
|
|
|
|
vacuolar transport
|
GO:0007034 |
34 |
0.046
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.046
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.046
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.046
|
Zebrafish |
|
|
protein maturation
|
GO:0051604 |
233 |
0.046
|
Rat |
|
|
peptide secretion
|
GO:0002790 |
51 |
0.046
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.046
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.046
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.045
|
|
|
|
cellular senescence
|
GO:0090398 |
34 |
0.045
|
|
|
|
notch receptor processing
|
GO:0007220 |
2 |
0.045
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.045
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.045
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.045
|
|
|
|
response to carbohydrate
|
GO:0009743 |
21 |
0.045
|
|
|
|
negative regulation of stress activated protein kinase signaling cascade
|
GO:0070303 |
19 |
0.044
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.044
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.044
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.044
|
|
