|
|
activation of mapk activity by adrenergic receptor signaling pathway
|
GO:0071883 |
3 |
0.969
|
|
|
|
adenylate cyclase inhibiting adrenergic receptor signaling pathway
|
GO:0071881 |
1 |
0.938
|
|
|
|
negative regulation of insulin secretion involved in cellular response to glucose stimulus
|
GO:0061179 |
1 |
0.920
|
|
|
|
adenylate cyclase inhibiting serotonin receptor signaling pathway
|
GO:0007198 |
2 |
0.897
|
|
|
|
sodium ion transport
|
GO:0006814 |
61 |
0.679
|
|
|
|
positive regulation of phosphatidylinositol biosynthetic process
|
GO:0010513 |
3 |
0.664
|
|
|
|
positive regulation of biomineral tissue development
|
GO:0070169 |
20 |
0.572
|
|
|
|
phospholipase c activating adrenergic receptor signaling pathway
|
GO:0071882 |
1 |
0.568
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.435
|
|
|
|
serotonin receptor signaling pathway
|
GO:0007210 |
11 |
0.426
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.369
|
|
|
|
desensitization of g protein coupled receptor protein signaling pathway by arrestin
|
GO:0002032 |
2 |
0.354
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.351
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.319
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.318
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.313
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.301
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.295
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.278
|
|
|
|
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway
|
GO:0035625 |
4 |
0.272
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.264
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.264
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.259
|
|
|
|
regulation of adenylate cyclase activity
|
GO:0045761 |
17 |
0.257
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.254
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.241
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.239
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.235
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.234
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.234
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.234
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.234
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.233
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.229
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.227
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.224
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.216
|
|
|
|
regulation of sensory perception of pain
|
GO:0051930 |
3 |
0.215
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.198
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
45 |
0.198
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.191
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.191
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.189
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.189
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.186
|
|
|
|
system process
|
GO:0003008 |
349 |
0.185
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.184
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.181
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.180
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.173
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.170
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.169
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.169
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
1 |
0.167
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.166
|
|
|
|
negative regulation of muscle contraction
|
GO:0045932 |
3 |
0.164
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
52 |
0.163
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.161
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.161
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.161
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.161
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.160
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.160
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.159
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.158
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.158
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.157
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.157
|
|
|
|
regulation of lipid catabolic process
|
GO:0050994 |
23 |
0.156
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.156
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.155
|
|
|
|
regulation of muscle organ development
|
GO:0048634 |
27 |
0.154
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.151
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.151
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.151
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.151
|
|
|
|
regulation of sensory perception
|
GO:0051931 |
3 |
0.150
|
|
|
|
positive regulation of adenylate cyclase activity
|
GO:0045762 |
12 |
0.143
|
|
|
|
regulation of potassium ion transport
|
GO:0043266 |
24 |
0.143
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.143
|
|
|
|
negative regulation of blood pressure
|
GO:0045776 |
3 |
0.141
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.139
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.138
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.137
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
38 |
0.136
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.134
|
|
|
|
biomineral tissue development
|
GO:0031214 |
39 |
0.134
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.133
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.133
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.132
|
|
|
|
negative regulation of systemic arterial blood pressure
|
GO:0003085 |
1 |
0.132
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.131
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.128
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.127
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.127
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
35 |
0.126
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.126
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.126
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.123
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.123
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.123
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.122
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.121
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.121
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.117
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.117
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.117
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.117
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.117
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.115
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.115
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.115
|
|
|
|
positive regulation of lipid biosynthetic process
|
GO:0046889 |
22 |
0.115
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.115
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.111
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
18 |
0.111
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.111
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.111
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.111
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.108
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.108
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.107
|
|
|
|
positive regulation of blood pressure
|
GO:0045777 |
3 |
0.106
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.105
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.105
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.104
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
14 |
0.104
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.103
|
|
|
|
regulation of bone mineralization
|
GO:0030500 |
29 |
0.103
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.103
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.103
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.103
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.102
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.102
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.101
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.100
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
38 |
0.100
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.099
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.098
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.097
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.096
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.096
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.096
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
24 |
0.095
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.095
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.094
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.094
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.094
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.094
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.092
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.092
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.091
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.090
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.090
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.090
|
|
|
|
bone mineralization
|
GO:0030282 |
34 |
0.089
|
|
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
4 |
0.089
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.089
|
|
|
|
adenylate cyclase activating dopamine receptor signaling pathway
|
GO:0007191 |
3 |
0.089
|
|
|
|
camp metabolic process
|
GO:0046058 |
61 |
0.088
|
|
|
|
negative regulation of platelet aggregation
|
GO:0090331 |
3 |
0.088
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.087
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.087
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.086
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.086
|
Human |
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
37 |
0.086
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.086
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.086
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.086
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.085
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.084
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.083
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.082
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.082
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.082
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.081
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
1 |
0.081
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.081
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.081
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.081
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.081
|
|
|
|
drinking behavior
|
GO:0042756 |
1 |
0.081
|
|
|
|
positive regulation of vasodilation
|
GO:0045909 |
4 |
0.081
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.080
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.080
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.080
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.080
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.079
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.079
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.078
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.078
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.078
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.078
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.078
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.078
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.078
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.077
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.077
|
|
|
|
positive regulation of muscle organ development
|
GO:0048636 |
7 |
0.077
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.077
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.077
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.076
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.076
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.076
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
32 |
0.075
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.075
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.075
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.075
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.075
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.074
|
|
|
|
intestine smooth muscle contraction
|
GO:0014827 |
2 |
0.074
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.074
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.073
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.072
|
|
|
|
skeletal muscle tissue growth
|
GO:0048630 |
2 |
0.072
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.072
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.071
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.071
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.071
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.071
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.070
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.070
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.069
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.069
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.069
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.069
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.068
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.067
|
|
|
|
positive regulation of bone mineralization
|
GO:0030501 |
19 |
0.067
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.067
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.067
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.066
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
50 |
0.066
|
|
|
|
adenylate cyclase activating adrenergic receptor signaling pathway
|
GO:0071880 |
3 |
0.066
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.066
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.066
|
|
|
|
diet induced thermogenesis
|
GO:0002024 |
2 |
0.065
|
|
|
|
platelet aggregation
|
GO:0070527 |
32 |
0.065
|
|
|
|
vasodilation
|
GO:0042311 |
4 |
0.065
|
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
38 |
0.065
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.065
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.065
|
|
|
|
regulation of the force of heart contraction
|
GO:0002026 |
6 |
0.065
|
|
|
|
respiratory gaseous exchange
|
GO:0007585 |
3 |
0.065
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.064
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.064
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.064
|
|
|
|
musculoskeletal movement
|
GO:0050881 |
17 |
0.064
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.064
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.063
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.063
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.062
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.062
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.062
|
|
|
|
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway
|
GO:0051482 |
6 |
0.062
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.061
|
|
|
|
regulation of oxidoreductase activity
|
GO:0051341 |
43 |
0.061
|
|
|
|
regulation of cyclase activity
|
GO:0031279 |
19 |
0.061
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
43 |
0.061
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.060
|
|
|
|
gastro intestinal system smooth muscle contraction
|
GO:0014831 |
2 |
0.060
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.060
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.060
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.060
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.059
|
|
|
|
activation of phospholipase c activity
|
GO:0007202 |
7 |
0.059
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.058
|
|
|
|
regulation of platelet aggregation
|
GO:0090330 |
4 |
0.058
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.058
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.058
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.057
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.057
|
|
|
|
skeletal muscle contraction
|
GO:0003009 |
16 |
0.057
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.057
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.057
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.056
|
|
|
|
positive regulation of phospholipid biosynthetic process
|
GO:0071073 |
4 |
0.056
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.056
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.056
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.056
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.056
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.055
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.055
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.055
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
45 |
0.055
|
|
|
|
negative regulation of sodium ion transmembrane transport
|
GO:1902306 |
2 |
0.055
|
|
|
|
regulation of coagulation
|
GO:0050818 |
44 |
0.055
|
|
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.055
|
|
|
|
phosphatidylinositol metabolic process
|
GO:0046488 |
53 |
0.055
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.054
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.054
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.054
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.054
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.053
|
|
|
|
negative regulation of lipid catabolic process
|
GO:0050995 |
9 |
0.053
|
|
|
|
receptor transactivation
|
GO:0035624 |
4 |
0.053
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.053
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.053
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.053
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.053
|
|
|
|
regulation of atpase activity
|
GO:0043462 |
25 |
0.052
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.052
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.052
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
47 |
0.052
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.052
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.052
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.051
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.051
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.051
|
|
|
|
response to dietary excess
|
GO:0002021 |
2 |
0.051
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.051
|
|
|
|
growth
|
GO:0040007 |
202 |
0.050
|
|
|
|
negative regulation of sodium ion transmembrane transporter activity
|
GO:2000650 |
2 |
0.050
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.050
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.050
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.050
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.049
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.049
|
|
|
|
adenylate cyclase inhibiting g protein coupled receptor signaling pathway
|
GO:0007193 |
22 |
0.049
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.049
|
|
|
|
lipid catabolic process
|
GO:0016042 |
84 |
0.049
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
50 |
0.049
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.049
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.049
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.048
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.048
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.048
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.048
|
Human |
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
38 |
0.048
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.048
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.048
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.048
|
|
|
|
negative regulation of homotypic cell cell adhesion
|
GO:0034111 |
3 |
0.048
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.048
|
|
|
|
regulation of biomineral tissue development
|
GO:0070167 |
31 |
0.048
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.048
|
|
|
|
camp mediated signaling
|
GO:0019933 |
23 |
0.048
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.047
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
0.047
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.047
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.047
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.047
|
|
|
|
regulation of striated muscle tissue development
|
GO:0016202 |
26 |
0.046
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.046
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.046
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.046
|
|
|
|
regulation of lyase activity
|
GO:0051339 |
23 |
0.046
|
|
|
|
endocardial cushion development
|
GO:0003197 |
3 |
0.046
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.045
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.045
|
|
|
|
sodium ion homeostasis
|
GO:0055078 |
14 |
0.044
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.044
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.044
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
51 |
0.044
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.044
|
|
|
|
regulation of camp mediated signaling
|
GO:0043949 |
13 |
0.044
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.044
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
26 |
0.044
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.043
|
Human |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.043
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.043
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.043
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.043
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.043
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.043
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.043
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.043
|
|
|
|
regulation of vasodilation
|
GO:0042312 |
4 |
0.042
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.042
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.042
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.042
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.041
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.041
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.041
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.041
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.041
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.041
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.040
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.040
|
|
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
19 |
0.040
|
|
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
24 |
0.040
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.040
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.040
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.040
|
|
|
|
positive regulation of camp mediated signaling
|
GO:0043950 |
10 |
0.040
|
|
|
|
multicellular organismal movement
|
GO:0050879 |
17 |
0.040
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.039
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.039
|
|
|
|
receptor internalization
|
GO:0031623 |
43 |
0.039
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.039
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.039
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.039
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.039
|
|
|
|
multicellular organismal metabolic process
|
GO:0044236 |
34 |
0.039
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.039
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.039
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.039
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.039
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.038
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.038
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.038
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.038
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.038
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.038
|
|
|
|
respiratory system process
|
GO:0003016 |
3 |
0.038
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.037
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.037
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.037
|
|
|
|
positive regulation of cyclase activity
|
GO:0031281 |
13 |
0.037
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.037
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.037
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.037
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.037
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.036
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.036
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.036
|
|
|
|
regulation of phospholipase activity
|
GO:0010517 |
26 |
0.036
|
|
|
|
regulation of sodium ion transmembrane transporter activity
|
GO:2000649 |
17 |
0.036
|
|
|
|
membrane protein ectodomain proteolysis
|
GO:0006509 |
33 |
0.036
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.036
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.035
|
|
|
|
regulation of cofactor metabolic process
|
GO:0051193 |
3 |
0.035
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
0.035
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
49 |
0.035
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.035
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.035
|
|
|
|
regulation of potassium ion transmembrane transport
|
GO:1901379 |
20 |
0.035
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.035
|
|
|
|
positive regulation of muscle tissue development
|
GO:1901863 |
7 |
0.035
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.035
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.035
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.035
|
|
|
|
cellular response to monoamine stimulus
|
GO:0071868 |
7 |
0.034
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.034
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
21 |
0.034
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.034
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.034
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.034
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.034
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.034
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.034
|
|
|
|
response to dexamethasone
|
GO:0071548 |
1 |
0.033
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.033
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.033
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.033
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.033
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.033
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.033
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
22 |
0.033
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.032
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.032
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.032
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.032
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.032
|
|
|
|
memory
|
GO:0007613 |
3 |
0.032
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.032
|
|
|
|
regulation of atp metabolic process
|
GO:1903578 |
29 |
0.032
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.031
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.031
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.031
|
|
|
|
regulation of tube size
|
GO:0035150 |
18 |
0.031
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.031
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.031
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.031
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.031
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.031
|
|
|
|
mesodermal cell fate commitment
|
GO:0001710 |
2 |
0.031
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.030
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.030
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.030
|
|
|
|
renal system process
|
GO:0003014 |
25 |
0.030
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.030
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
35 |
0.030
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.030
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.030
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.030
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.030
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.030
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
15 |
0.030
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.030
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.030
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.030
|
|
|
|
positive regulation of calcium ion transport
|
GO:0051928 |
51 |
0.029
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.029
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.029
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.029
|
|
