|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.982
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.979
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.961
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.958
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.957
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.952
|
Human Mouse |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.945
|
Human Mouse |
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.937
|
Human |
|
|
actin filament organization
|
GO:0007015 |
128 |
0.931
|
Human |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.927
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.926
|
Human Mouse |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.910
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.909
|
Human Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.903
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.902
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.901
|
Human Mouse |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.901
|
Human |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.900
|
Human Mouse |
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.895
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.895
|
Human Mouse |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.895
|
Human Mouse |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.894
|
Human Mouse |
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.889
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.853
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.852
|
Human Mouse |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.850
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.834
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.832
|
Human Mouse |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.830
|
Human Mouse |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.823
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.815
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.810
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.804
|
Human Mouse |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.795
|
Human |
|
|
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway
|
GO:0035625 |
4 |
0.788
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.786
|
Human |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.774
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.738
|
Human Mouse |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.734
|
Human Mouse |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.695
|
Human Mouse |
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.686
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.669
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.647
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.646
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.635
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.632
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.624
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.618
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.617
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.607
|
Human Mouse |
|
|
synaptic vesicle endocytosis
|
GO:0048488 |
2 |
0.605
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.603
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.596
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.594
|
|
|
|
dendritic spine maintenance
|
GO:0097062 |
1 |
0.590
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.581
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.580
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.579
|
Human |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.577
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.571
|
Human Mouse |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.558
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.556
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.555
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.538
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.530
|
Human Mouse |
|
|
negative regulation of alpha beta t cell proliferation
|
GO:0046642 |
1 |
0.522
|
|
|
|
regulation of b cell receptor signaling pathway
|
GO:0050855 |
4 |
0.520
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.516
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.504
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.502
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.500
|
Human |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.498
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.495
|
Human |
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.492
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.487
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.480
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.480
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.477
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.475
|
Human Mouse |
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.464
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.458
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.455
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.441
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.440
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.437
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.435
|
Human |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.434
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.432
|
Human Mouse |
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.428
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.423
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.419
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.419
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.403
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.402
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.400
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.400
|
Human Mouse |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.396
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.395
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.394
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.390
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.388
|
|
|
|
membrane protein proteolysis
|
GO:0033619 |
38 |
0.387
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.384
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.381
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.377
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.369
|
Human Mouse |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.369
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.366
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.364
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.357
|
Human Mouse |
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
2 |
0.355
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.345
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.344
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.337
|
Human Mouse |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.336
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.333
|
|
|
|
regulation of microtubule polymerization
|
GO:0031113 |
12 |
0.328
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.327
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.319
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.318
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.315
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.310
|
Human Mouse |
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.305
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.304
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.304
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.303
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.302
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.298
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.295
|
Human Mouse |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.286
|
Human Mouse |
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.284
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.281
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.277
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.277
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.275
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.274
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.265
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.264
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.262
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.261
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.259
|
Human Mouse |
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.258
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.256
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.255
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.254
|
|
|
|
gliogenesis
|
GO:0042063 |
21 |
0.251
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.246
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.246
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.244
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.242
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.238
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.237
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.230
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.227
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.224
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.223
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.222
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.215
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.212
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.209
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.209
|
Human Mouse |
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.207
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.206
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.204
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.202
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.200
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.200
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.197
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.197
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.197
|
|
|
|
myotube differentiation
|
GO:0014902 |
22 |
0.197
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.195
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.193
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.193
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.192
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.190
|
|
|
|
hormone biosynthetic process
|
GO:0042446 |
22 |
0.189
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.187
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.186
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.185
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.184
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.182
|
Human Mouse |
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.181
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.180
|
Human Mouse |
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.180
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.179
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.177
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.175
|
|
|
|
activation of mapk activity by adrenergic receptor signaling pathway
|
GO:0071883 |
3 |
0.173
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.172
|
Human |
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.172
|
|
|
|
ephrin receptor signaling pathway
|
GO:0048013 |
15 |
0.172
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.167
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.167
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.166
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.166
|
|
|
|
negative regulation of endothelial cell apoptotic process
|
GO:2000352 |
16 |
0.165
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.164
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.163
|
|
|
|
receptor transactivation
|
GO:0035624 |
4 |
0.160
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.158
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.155
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.155
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.155
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.154
|
|
|
|
negative regulation of transforming growth factor beta1 production
|
GO:0032911 |
2 |
0.154
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.154
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.148
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.148
|
Human |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.147
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.146
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.144
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.144
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.144
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.144
|
|
|
|
positive regulation of vasodilation
|
GO:0045909 |
4 |
0.141
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.141
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.140
|
Human Mouse |
|
|
response to hormone
|
GO:0009725 |
175 |
0.139
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.139
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.139
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.138
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.137
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.137
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.136
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.136
|
Human Mouse |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.135
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.135
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.135
|
|
|
|
regulation of macrophage chemotaxis
|
GO:0010758 |
4 |
0.134
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
2 |
0.133
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.133
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.132
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.131
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.129
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.128
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.128
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.128
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.127
|
Human Mouse |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.127
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.127
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.127
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.126
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.125
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
4 |
0.125
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.124
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.124
|
|
|
|
activation of janus kinase activity
|
GO:0042976 |
7 |
0.122
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.119
|
|
|
|
regulation of inositol phosphate biosynthetic process
|
GO:0010919 |
3 |
0.118
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.117
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.117
|
|
|
|
regulation of myoblast fusion
|
GO:1901739 |
1 |
0.116
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.114
|
|
|
|
epithelial tube branching involved in lung morphogenesis
|
GO:0060441 |
4 |
0.114
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.113
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.112
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.111
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.110
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.110
|
Human Mouse |
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.109
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.107
|
Human |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.107
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.105
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.104
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.101
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.100
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.099
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.099
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.098
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.098
|
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.098
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.098
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.096
|
|
|
|
regulation of vasodilation
|
GO:0042312 |
4 |
0.096
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.094
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.093
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.092
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.092
|
Human Mouse |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.091
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.091
|
|
|
|
regulation of cgmp mediated signaling
|
GO:0010752 |
1 |
0.090
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.090
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.090
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.089
|
|
|
|
lung growth
|
GO:0060437 |
2 |
0.089
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.089
|
|
|
|
hormone metabolic process
|
GO:0042445 |
61 |
0.088
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.087
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.086
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.086
|
Human Mouse |
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.086
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.085
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.084
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.083
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.083
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.082
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.082
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.082
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.082
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.082
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.081
|
|
|
|
elastic fiber assembly
|
GO:0048251 |
3 |
0.081
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.081
|
|
|
|
tissue homeostasis
|
GO:0001894 |
63 |
0.081
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.080
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.080
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.080
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.080
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.079
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.079
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.079
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.078
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.078
|
Human Mouse |
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.077
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.077
|
|
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.077
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.076
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.076
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.075
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.075
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.074
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.073
|
Human Mouse |
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.073
|
|
|
|
regulation of hormone metabolic process
|
GO:0032350 |
14 |
0.073
|
|
|
|
cell adhesion mediated by integrin
|
GO:0033627 |
27 |
0.071
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.071
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.071
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.071
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.070
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.069
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
21 |
0.069
|
|
|
|
regulation of endothelial cell apoptotic process
|
GO:2000351 |
24 |
0.069
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.068
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.068
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.068
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.068
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.068
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
2 |
0.067
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.067
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.067
|
|
|
|
regulation of transforming growth factor beta1 production
|
GO:0032908 |
3 |
0.067
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.066
|
|
|
|
protein kinase c signaling
|
GO:0070528 |
17 |
0.066
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.066
|
|
|
|
neurotrophin trk receptor signaling pathway
|
GO:0048011 |
4 |
0.066
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.065
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.065
|
|
|
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
38 |
0.065
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
47 |
0.064
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.064
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.064
|
|
|
|
regulation of clathrin mediated endocytosis
|
GO:2000369 |
4 |
0.063
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.062
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.062
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.061
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.061
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.061
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.061
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.059
|
|
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
27 |
0.059
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.059
|
|
|
|
rap protein signal transduction
|
GO:0032486 |
7 |
0.058
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.058
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.058
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.058
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.058
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.058
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.057
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.057
|
|
|
|
positive regulation of cell proliferation by vegf activated platelet derived growth factor receptor signaling pathway
|
GO:0038091 |
3 |
0.057
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.057
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.057
|
Human |
|
|
central nervous system neuron axonogenesis
|
GO:0021955 |
3 |
0.056
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.056
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.056
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.056
|
|
|
|
positive regulation of necrotic cell death
|
GO:0010940 |
4 |
0.056
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.056
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.056
|
|
|
|
negative regulation of fibroblast growth factor receptor signaling pathway
|
GO:0040037 |
2 |
0.055
|
|
|
|
regulation of cell adhesion mediated by integrin
|
GO:0033628 |
22 |
0.055
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.055
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.055
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
1 |
0.054
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.054
|
|
|
|
response to mercury ion
|
GO:0046689 |
4 |
0.053
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
39 |
0.053
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
26 |
0.053
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.053
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.052
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.052
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.051
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.051
|
|
|
|
bone resorption
|
GO:0045453 |
6 |
0.051
|
|
|
|
regulation of lipase activity
|
GO:0060191 |
37 |
0.050
|
|
|
|
positive regulation of cell matrix adhesion
|
GO:0001954 |
23 |
0.050
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.050
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
14 |
0.050
|
|
|
|
embryonic viscerocranium morphogenesis
|
GO:0048703 |
1 |
0.050
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.049
|
Human |
|
|
positive regulation of aldosterone metabolic process
|
GO:0032346 |
2 |
0.049
|
|
|
|
regulation of lymphocyte migration
|
GO:2000401 |
22 |
0.049
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.049
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.049
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.048
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.048
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.048
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.048
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.048
|
|
|
|
apoptotic cell clearance
|
GO:0043277 |
12 |
0.048
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.047
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.047
|
|
|
|
vascular endothelial growth factor receptor 1 signaling pathway
|
GO:0036323 |
1 |
0.047
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.047
|
|
|
|
growth
|
GO:0040007 |
202 |
0.047
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.046
|
Human Mouse |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.046
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.046
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
26 |
0.046
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.046
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.046
|
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.046
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
7 |
0.046
|
|
|
|
chromatin assembly
|
GO:0031497 |
61 |
0.045
|
|
|
|
regulation of potassium ion transport
|
GO:0043266 |
24 |
0.045
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.045
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.045
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.044
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.044
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.044
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.044
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
27 |
0.044
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.044
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.044
|
|
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
41 |
0.043
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.043
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.043
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.042
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.042
|
|
|
|
response to cocaine
|
GO:0042220 |
1 |
0.041
|
|
|
|
negative regulation of t cell receptor signaling pathway
|
GO:0050860 |
4 |
0.041
|
|
|
|
negative regulation of epidermal growth factor activated receptor activity
|
GO:0007175 |
6 |
0.041
|
|
|
|
transforming growth factor beta1 production
|
GO:0032905 |
3 |
0.041
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
3 |
0.041
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.041
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.041
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.040
|
|
|
|
cell recognition
|
GO:0008037 |
9 |
0.040
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.040
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.039
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.039
|
|
|
|
positive regulation of cyclin dependent protein serine threonine kinase activity involved in g1 s transition of mitotic cell cycle
|
GO:0031659 |
8 |
0.039
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.039
|
|
|
|
platelet activation
|
GO:0030168 |
44 |
0.039
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.038
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.038
|
|
|
|
chemokine production
|
GO:0032602 |
32 |
0.038
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.038
|
|
|
|
positive regulation of t cell tolerance induction
|
GO:0002666 |
2 |
0.038
|
|
|
|
regulation of lamellipodium morphogenesis
|
GO:2000392 |
4 |
0.038
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.038
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.038
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.037
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.037
|
|
|
|
negative regulation of platelet aggregation
|
GO:0090331 |
3 |
0.037
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.037
|
|
|
|
positive regulation of aldosterone biosynthetic process
|
GO:0032349 |
2 |
0.037
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.037
|
|
|
|
vegf activated platelet derived growth factor receptor signaling pathway
|
GO:0038086 |
3 |
0.037
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.037
|
|
|
|
negative regulation of leukocyte activation
|
GO:0002695 |
26 |
0.037
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.036
|
|
|
|
negative regulation of wound healing
|
GO:0061045 |
25 |
0.036
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.036
|
|
|
|
regulation of extracellular vesicular exosome assembly
|
GO:1903551 |
4 |
0.036
|
|
|
|
regulation of lymphocyte chemotaxis
|
GO:1901623 |
12 |
0.036
|
|
|
|
vasodilation
|
GO:0042311 |
4 |
0.036
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.036
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.036
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.036
|
|
|
|
lymphocyte chemotaxis
|
GO:0048247 |
17 |
0.036
|
|
|
|
phagocytosis engulfment
|
GO:0006911 |
7 |
0.036
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.036
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.035
|
|
