Homo sapiens

106 known processes

ATF4

activating transcription factor 4 (tax-responsive enhancer element B67)

(Aliases: CREB-2,TXREB,CREB2,TAXREB67)

ATF4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to biotic stimulus GO:0009607 276 0.908
collateral sprouting GO:0048668 2 0.902
regulation of cell cycle GO:0051726 393 0.838
regulation of determination of dorsal identity GO:2000015 2 0.775
cellular response to biotic stimulus GO:0071216 71 0.773
blood vessel maturation GO:0001955 1 0.760
apoptotic signaling pathway GO:0097190 268 0.753
Mouse
response to endoplasmic reticulum stress GO:0034976 49 0.726
response to oxidative stress GO:0006979 121 0.719
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.686
cellular response to endogenous stimulus GO:0071495 336 0.674
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.669
negative regulation of cell differentiation GO:0045596 171 0.659
response to oxygen containing compound GO:1901700 369 0.631
modification dependent macromolecule catabolic process GO:0043632 212 0.621
response to external biotic stimulus GO:0043207 261 0.603
lipopolysaccharide mediated signaling pathway GO:0031663 26 0.588
response to organonitrogen compound GO:0010243 156 0.573
mitotic cell cycle GO:0000278 326 0.566
regulation of kinase activity GO:0043549 314 0.561
intrinsic apoptotic signaling pathway GO:0097193 127 0.550
Mouse
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 17 0.550
regulation of lipid metabolic process GO:0019216 96 0.538
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.536
regulation of protein serine threonine kinase activity GO:0071900 179 0.526
ubiquitin dependent protein catabolic process GO:0006511 206 0.521
regulation of smooth muscle cell proliferation GO:0048660 28 0.520
rhythmic behavior GO:0007622 2 0.516
response to nitrogen compound GO:1901698 184 0.510
myeloid cell differentiation GO:0030099 117 0.500
regulation of ligase activity GO:0051340 29 0.468
cellular response to nitrogen compound GO:1901699 144 0.467
negative regulation of smooth muscle cell migration GO:0014912 7 0.465
cellular protein catabolic process GO:0044257 261 0.456
negative regulation of multi organism process GO:0043901 92 0.454
hemopoiesis GO:0030097 180 0.447
carbohydrate metabolic process GO:0005975 207 0.441
Mouse
response to other organism GO:0051707 261 0.434
regulation of multi organism process GO:0043900 157 0.432
monocarboxylic acid metabolic process GO:0032787 185 0.428
protein catabolic process GO:0030163 325 0.426
cell cycle phase transition GO:0044770 173 0.419
negative regulation of developmental process GO:0051093 247 0.407
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 12 0.404
Mouse
stress activated protein kinase signaling cascade GO:0031098 94 0.396
small molecule biosynthetic process GO:0044283 157 0.394
erythrocyte differentiation GO:0030218 28 0.393
interleukin 10 biosynthetic process GO:0042091 2 0.390
negative regulation of interleukin 10 production GO:0032693 7 0.389
positive regulation of catabolic process GO:0009896 310 0.371
cytokine production GO:0001816 247 0.366
cytokine biosynthetic process GO:0042089 37 0.353
monocarboxylic acid biosynthetic process GO:0072330 67 0.352
neuromuscular junction development GO:0007528 3 0.349
neuron projection regeneration GO:0031102 1 0.347
circadian behavior GO:0048512 2 0.344
cellular response to oxygen containing compound GO:1901701 276 0.343
cellular response to molecule of bacterial origin GO:0071219 62 0.341
modification dependent protein catabolic process GO:0019941 209 0.338
regulation of fat cell differentiation GO:0045598 23 0.335
mitotic cell cycle phase transition GO:0044772 162 0.334
regulation of lipid biosynthetic process GO:0046890 47 0.334
negative regulation of phosphorus metabolic process GO:0010563 267 0.334
axon regeneration GO:0031103 1 0.331
regeneration GO:0031099 4 0.326
cellular ketone metabolic process GO:0042180 80 0.325
regulation of cytokine production GO:0001817 232 0.321
leukocyte differentiation GO:0002521 98 0.314
positive regulation of proteolysis GO:0045862 142 0.312
positive regulation of cellular catabolic process GO:0031331 284 0.304
canonical wnt signaling pathway GO:0060070 116 0.295
regulation of mitotic cell cycle GO:0007346 189 0.290
response to inorganic substance GO:0010035 127 0.282
oogenesis GO:0048477 2 0.280
mitotic cell cycle process GO:1903047 286 0.280
cellular macromolecule catabolic process GO:0044265 380 0.270
circadian rhythm GO:0007623 21 0.267
Mouse
rhythmic process GO:0048511 31 0.266
Mouse
locomotory behavior GO:0007626 1 0.264
blood vessel development GO:0001568 172 0.263
negative regulation of protein phosphorylation GO:0001933 140 0.263
negative regulation of fat cell differentiation GO:0045599 9 0.256
regulation of lipopolysaccharide mediated signaling pathway GO:0031664 13 0.252
determination of dorsal identity GO:0048263 4 0.243
response to organic cyclic compound GO:0014070 204 0.241
cell activation GO:0001775 213 0.237
response to peptide hormone GO:0043434 61 0.237
determination of dorsal ventral asymmetry GO:0048262 4 0.232
lipid biosynthetic process GO:0008610 177 0.230
positive regulation of cellular protein catabolic process GO:1903364 37 0.230
negative regulation of phosphate metabolic process GO:0045936 267 0.224
post embryonic development GO:0009791 2 0.221
negative regulation of lipid metabolic process GO:0045833 38 0.220
response to hormone GO:0009725 175 0.217
intra s dna damage checkpoint GO:0031573 4 0.210
regulation of cell cycle process GO:0010564 266 0.209
regulation of cellular protein catabolic process GO:1903362 96 0.209
response to temperature stimulus GO:0009266 22 0.206
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.205
regulation of cytokine biosynthetic process GO:0042035 35 0.204
cellular response to hormone stimulus GO:0032870 125 0.202
forebrain generation of neurons GO:0021872 3 0.202
hematopoietic or lymphoid organ development GO:0048534 186 0.201
cellular response to lipopolysaccharide GO:0071222 57 0.200
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.195
calcium ion transport GO:0006816 147 0.193
regulation of protein kinase activity GO:0045859 289 0.191
response to peptide GO:1901652 65 0.189
positive regulation of ubiquitin protein transferase activity GO:0051443 18 0.189
proteasomal protein catabolic process GO:0010498 176 0.187
regulation of proteolysis GO:0030162 293 0.186
negative regulation of response to biotic stimulus GO:0002832 18 0.186
response to axon injury GO:0048678 1 0.185
response to drug GO:0042493 81 0.183
immune effector process GO:0002252 159 0.182
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.175
negative regulation of smooth muscle cell proliferation GO:0048662 14 0.174
positive regulation of cytokine production GO:0001819 167 0.174
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.173
chemical homeostasis GO:0048878 306 0.172
trna aminoacylation for protein translation GO:0006418 8 0.167
response to abiotic stimulus GO:0009628 336 0.167
regulation of cellular ketone metabolic process GO:0010565 50 0.167
regulation of glucose transport GO:0010827 23 0.165
response to reactive oxygen species GO:0000302 61 0.162
positive regulation of apoptotic process GO:0043065 246 0.161
Mouse
protein ubiquitination GO:0016567 314 0.156
response to virus GO:0009615 126 0.156
response to lipid GO:0033993 206 0.156
regulation of neuron death GO:1901214 56 0.155
cellular response to unfolded protein GO:0034620 16 0.155
compound eye development GO:0048749 1 0.152
mitotic nuclear division GO:0007067 119 0.150
sequestering of calcium ion GO:0051208 17 0.147
protein modification by small protein conjugation GO:0032446 342 0.147
negative regulation of cell cycle GO:0045786 193 0.147
dna templated transcription termination GO:0006353 3 0.146
reproductive process GO:0022414 106 0.145
response to unfolded protein GO:0006986 24 0.144
negative regulation of protein metabolic process GO:0051248 391 0.144
regulation of protein catabolic process GO:0042176 155 0.142
regulation of fatty acid metabolic process GO:0019217 24 0.141
positive regulation of protein catabolic process GO:0045732 75 0.136
cellular response to peptide GO:1901653 59 0.135
cytoplasmic transport GO:0016482 379 0.133
negative regulation of cell cycle process GO:0010948 121 0.132
response to topologically incorrect protein GO:0035966 29 0.131
negative regulation of catalytic activity GO:0043086 335 0.127
positive regulation of neuron death GO:1901216 14 0.126
Mouse
carbohydrate transport GO:0008643 37 0.126
fat cell differentiation GO:0045444 32 0.125
g2 m transition of mitotic cell cycle GO:0000086 41 0.125
fatty acid biosynthetic process GO:0006633 46 0.123
regulation of fatty acid biosynthetic process GO:0042304 9 0.119
response to insulin GO:0032868 45 0.119
regulation of mitotic cell cycle phase transition GO:1901990 118 0.115
sequestering of metal ion GO:0051238 24 0.115
positive regulation of protein binding GO:0032092 24 0.115
negative regulation of phosphorylation GO:0042326 174 0.115
erythrocyte homeostasis GO:0034101 31 0.115
regulation of transferase activity GO:0051338 355 0.111
regulation of ubiquitin protein transferase activity GO:0051438 28 0.110
female gamete generation GO:0007292 2 0.110
regulation of cell motility GO:2000145 299 0.109
cellular amino acid metabolic process GO:0006520 116 0.108
smooth muscle cell proliferation GO:0048659 28 0.107
negative regulation of cell death GO:0060548 345 0.106
cellular homeostasis GO:0019725 196 0.105
negative regulation of locomotion GO:0040013 118 0.105
response to molecule of bacterial origin GO:0002237 82 0.105
developmental growth involved in morphogenesis GO:0060560 23 0.105
negative regulation of cellular component organization GO:0051129 235 0.104
positive regulation of dna metabolic process GO:0051054 73 0.103
regulation of interleukin 10 biosynthetic process GO:0045074 2 0.102
regulation of locomotion GO:0040012 329 0.100
response to hydrogen peroxide GO:0042542 40 0.099
muscle cell proliferation GO:0033002 35 0.097
regulation of homeostatic process GO:0032844 121 0.096
cellular response to reactive oxygen species GO:0034614 50 0.096
enzyme linked receptor protein signaling pathway GO:0007167 303 0.096
negative regulation of cell division GO:0051782 31 0.096
carboxylic acid biosynthetic process GO:0046394 97 0.095
regulation of cell differentiation GO:0045595 393 0.093
cellular divalent inorganic cation homeostasis GO:0072503 128 0.093
cellular response to lipid GO:0071396 127 0.092
nuclear division GO:0000280 128 0.092
er nucleus signaling pathway GO:0006984 23 0.091
membrane organization GO:0061024 292 0.090
embryo development GO:0009790 123 0.088
embryonic organ development GO:0048568 36 0.088
cellular response to peptide hormone stimulus GO:0071375 56 0.087
regulation of myeloid cell differentiation GO:0045637 81 0.086
negative regulation of cell proliferation GO:0008285 228 0.084
negative regulation of organelle organization GO:0010639 126 0.084
associative learning GO:0008306 1 0.083
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.083
developmental cell growth GO:0048588 18 0.082
peptidyl lysine acetylation GO:0018394 101 0.081
regulation of canonical wnt signaling pathway GO:0060828 88 0.080
regulation of nuclear division GO:0051783 65 0.079
termination of rna polymerase ii transcription GO:0006369 1 0.077
single organism cellular localization GO:1902580 332 0.076
regulation of interferon gamma biosynthetic process GO:0045072 8 0.075
negative regulation of lipid biosynthetic process GO:0051055 22 0.075
cellular response to oxidative stress GO:0034599 85 0.074
carbohydrate biosynthetic process GO:0016051 42 0.074
Mouse
positive regulation of cell death GO:0010942 263 0.073
Mouse
negative regulation of cell motility GO:2000146 104 0.073
gland development GO:0048732 48 0.072
regulation of response to biotic stimulus GO:0002831 55 0.071
negative regulation of cellular protein metabolic process GO:0032269 353 0.070
anatomical structure formation involved in morphogenesis GO:0048646 284 0.070
organelle fission GO:0048285 149 0.067
lipid metabolic process GO:0006629 381 0.067
negative regulation of cellular component movement GO:0051271 106 0.066
cellular lipid metabolic process GO:0044255 303 0.065
regulation of cellular component movement GO:0051270 334 0.064
smad protein signal transduction GO:0060395 10 0.064
negative regulation of lipopolysaccharide mediated signaling pathway GO:0031665 7 0.063
negative regulation of mitotic cell cycle GO:0045930 102 0.061
positive regulation of ligase activity GO:0051351 19 0.061
cellular component morphogenesis GO:0032989 314 0.060
muscle cell development GO:0055001 29 0.060
hexose metabolic process GO:0019318 55 0.060
Mouse
cytokine metabolic process GO:0042107 38 0.060
single organism membrane organization GO:0044802 268 0.059
l serine metabolic process GO:0006563 5 0.059
interleukin 10 production GO:0032613 17 0.059
divalent metal ion transport GO:0070838 152 0.059
lymphocyte mediated immunity GO:0002449 48 0.058
negative regulation of protein kinase activity GO:0006469 98 0.057
regulation of striated muscle cell differentiation GO:0051153 25 0.057
alpha amino acid metabolic process GO:1901605 72 0.056
regulation of cell migration GO:0030334 289 0.056
smooth muscle cell migration GO:0014909 18 0.056
positive regulation of protein ubiquitination GO:0031398 53 0.056
regulation of cellular amine metabolic process GO:0033238 11 0.056
negative regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress GO:1990441 1 0.056
positive regulation of dna repair GO:0045739 25 0.055
negative regulation of response to external stimulus GO:0032102 83 0.055
muscle cell migration GO:0014812 19 0.055
cellular response to insulin stimulus GO:0032869 41 0.054
organonitrogen compound biosynthetic process GO:1901566 200 0.054
negative regulation of kinase activity GO:0033673 106 0.053
jnk cascade GO:0007254 80 0.052
lymphocyte activation GO:0046649 133 0.051
cardiovascular system development GO:0072358 262 0.051
regulation of protein binding GO:0043393 66 0.051
negative regulation of homeostatic process GO:0032845 59 0.051
positive regulation of transferase activity GO:0051347 227 0.051
response to bacterium GO:0009617 144 0.051
regulation of muscle cell differentiation GO:0051147 31 0.050
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.050
monosaccharide transport GO:0015749 32 0.050
forebrain neuron development GO:0021884 2 0.049
regulation of dna templated transcription in response to stress GO:0043620 18 0.049
glucose transport GO:0015758 30 0.048
maintenance of location GO:0051235 112 0.048
hexose transport GO:0008645 30 0.047
cellular response to organonitrogen compound GO:0071417 124 0.047
cellular response to heat GO:0034605 14 0.047
cellular chemical homeostasis GO:0055082 180 0.047
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.047
leukocyte activation GO:0045321 164 0.046
stress activated mapk cascade GO:0051403 93 0.046
cellular ion homeostasis GO:0006873 168 0.046
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.045
regulation of smooth muscle cell migration GO:0014910 15 0.045
cellular calcium ion homeostasis GO:0006874 117 0.045
amine metabolic process GO:0009308 44 0.044
generation of neurons GO:0048699 152 0.044
chromatin organization GO:0006325 351 0.044
positive regulation of binding GO:0051099 45 0.044
tripartite regional subdivision GO:0007351 2 0.043
cell killing GO:0001906 34 0.043
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.043
myoblast differentiation GO:0045445 21 0.042
negative regulation of humoral immune response GO:0002921 7 0.042
regulation of mapk cascade GO:0043408 262 0.042
coenzyme metabolic process GO:0006732 65 0.042
negative regulation of protein modification process GO:0031400 200 0.042
regulation of muscle organ development GO:0048634 27 0.041
positive regulation of interferon gamma production GO:0032729 26 0.041
serine family amino acid metabolic process GO:0009069 12 0.041
cation transport GO:0006812 331 0.041
regulation of cell division GO:0051302 116 0.041
aging GO:0007568 66 0.041
neuron differentiation GO:0030182 138 0.041
one carbon metabolic process GO:0006730 1 0.040
mrna transcription from rna polymerase ii promoter GO:0042789 6 0.040
negative regulation of transferase activity GO:0051348 124 0.040
striated muscle cell differentiation GO:0051146 43 0.040
multicellular organismal aging GO:0010259 3 0.040
regulation of viral process GO:0050792 103 0.039
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.039
cellular response to dna damage stimulus GO:0006974 379 0.039
negative regulation of oxidative stress induced cell death GO:1903202 17 0.039
cellular metal ion homeostasis GO:0006875 146 0.039
divalent inorganic cation homeostasis GO:0072507 136 0.039
cell development GO:0048468 328 0.039
negative regulation of gliogenesis GO:0014014 3 0.038
anterior posterior axis specification GO:0009948 2 0.038
forebrain neuron differentiation GO:0021879 3 0.038
cellular response to hydrogen peroxide GO:0070301 37 0.038
negative regulation of intracellular signal transduction GO:1902532 183 0.038
amino acid activation GO:0043038 12 0.037
negative regulation of cell migration GO:0030336 102 0.037
positive regulation of interleukin 8 production GO:0032757 36 0.037
cellular amine metabolic process GO:0044106 41 0.037
trna metabolic process GO:0006399 35 0.036
response to calcium ion GO:0051592 46 0.036
anatomical structure maturation GO:0071695 9 0.036
cell morphogenesis GO:0000902 296 0.035
determination of adult lifespan GO:0008340 2 0.035
response to extracellular stimulus GO:0009991 85 0.035
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.035
monosaccharide metabolic process GO:0005996 74 0.035
Mouse
regulation of wnt signaling pathway GO:0030111 123 0.035
proline transport GO:0015824 4 0.034
regulation of response to dna damage stimulus GO:2001020 94 0.034
cell division GO:0051301 168 0.034
regulation of ion homeostasis GO:2000021 73 0.034
negative regulation of cytokine biosynthetic process GO:0042036 11 0.034
negative regulation of glial cell proliferation GO:0060253 2 0.034
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.033
negative regulation of creb transcription factor activity GO:0032792 1 0.033
embryonic placenta development GO:0001892 1 0.033
nucleoside triphosphate catabolic process GO:0009143 394 0.032
reproduction GO:0000003 63 0.032
regulation of map kinase activity GO:0043405 108 0.032
muscle tissue development GO:0060537 62 0.032
cellular response to growth factor stimulus GO:0071363 197 0.032
ncrna metabolic process GO:0034660 108 0.032
negative regulation of transport GO:0051051 176 0.031
circulatory system development GO:0072359 262 0.031
positive regulation of myeloid leukocyte differentiation GO:0002763 24 0.031
negative regulation of cell cycle phase transition GO:1901988 89 0.031
nitrogen compound transport GO:0071705 191 0.031
syncytium formation by plasma membrane fusion GO:0000768 2 0.031
negative regulation of multicellular organismal process GO:0051241 317 0.031
interspecies interaction between organisms GO:0044419 156 0.031
nervous system development GO:0007399 293 0.031
immune system development GO:0002520 195 0.031
growth GO:0040007 202 0.031
cell projection morphogenesis GO:0048858 129 0.030
modification by host of symbiont morphology or physiology GO:0051851 26 0.030
metal ion transport GO:0030001 272 0.030
response to cytokine GO:0034097 232 0.030
response to transforming growth factor beta GO:0071559 94 0.030
regulation of dna repair GO:0006282 47 0.030
epithelium development GO:0060429 227 0.029
single organism carbohydrate metabolic process GO:0044723 193 0.029
Mouse
neuron development GO:0048666 113 0.029
vesicle mediated transport GO:0016192 371 0.029
calcium ion homeostasis GO:0055074 122 0.029
muscle cell differentiation GO:0042692 63 0.029
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 9 0.029
regulation of binding GO:0051098 111 0.028
positive regulation of neuron apoptotic process GO:0043525 8 0.028
Mouse
neuron projection development GO:0031175 106 0.028
positive regulation of cellular amine metabolic process GO:0033240 7 0.028
positive regulation of programmed cell death GO:0043068 249 0.028
Mouse
vasculature development GO:0001944 181 0.027
autophagy GO:0006914 88 0.027
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.027
response to nutrient GO:0007584 20 0.027
positive regulation of neural precursor cell proliferation GO:2000179 2 0.027
signal transduction by phosphorylation GO:0023014 297 0.026
cell part morphogenesis GO:0032990 137 0.026
purine nucleoside triphosphate catabolic process GO:0009146 392 0.026
response to fungus GO:0009620 4 0.026
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.026
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.026
positive regulation of immune system process GO:0002684 283 0.026
translation GO:0006412 132 0.026
response to starvation GO:0042594 59 0.026
posttranscriptional regulation of gene expression GO:0010608 213 0.026
ribonucleoside triphosphate metabolic process GO:0009199 412 0.026
oxidation reduction process GO:0055114 396 0.026
mapk cascade GO:0000165 288 0.026
positive regulation of cell proliferation GO:0008284 301 0.025
cation homeostasis GO:0055080 189 0.025
wnt signaling pathway GO:0016055 156 0.025
sleep GO:0030431 2 0.025
regulation of cell development GO:0060284 161 0.025
regulation of carbohydrate metabolic process GO:0006109 54 0.025
patterning of blood vessels GO:0001569 2 0.024
interferon gamma production GO:0032609 39 0.024
histone acetylation GO:0016573 93 0.024
single organism reproductive process GO:0044702 98 0.024
brain development GO:0007420 97 0.024
cell death in response to oxidative stress GO:0036473 29 0.024
innate immune response GO:0045087 178 0.024
cell growth GO:0016049 160 0.024
mrna transcription GO:0009299 8 0.024
positive regulation of chromatin modification GO:1903310 30 0.024
antimicrobial humoral response GO:0019730 26 0.024
leukocyte mediated immunity GO:0002443 59 0.023
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.023
internal protein amino acid acetylation GO:0006475 101 0.023
neuron apoptotic process GO:0051402 39 0.022
Mouse
negative regulation of apoptotic process GO:0043066 316 0.022
neuron death GO:0070997 65 0.022
cellular response to topologically incorrect protein GO:0035967 19 0.022
negative regulation of mitosis GO:0045839 24 0.022
negative regulation of cytokine production GO:0001818 82 0.022
response to wounding GO:0009611 168 0.022
circulatory system process GO:0003013 113 0.022
positive regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000060 3 0.022
purine nucleoside triphosphate metabolic process GO:0009144 412 0.022
neuron death in response to oxidative stress GO:0036475 9 0.022
anterior posterior axis specification embryo GO:0008595 2 0.022
signal transduction in response to dna damage GO:0042770 57 0.022
purine ribonucleoside metabolic process GO:0046128 437 0.021
muscle structure development GO:0061061 98 0.021
oocyte differentiation GO:0009994 2 0.021
regulation of immune response GO:0050776 201 0.021
regulation of viral transcription GO:0046782 34 0.021
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.021
purine nucleotide catabolic process GO:0006195 405 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.021
carbohydrate homeostasis GO:0033500 31 0.020
positive regulation of cytokine biosynthetic process GO:0042108 25 0.020
transmembrane transport GO:0055085 399 0.020
regulation of myoblast differentiation GO:0045661 12 0.020
behavior GO:0007610 112 0.020
positive regulation of cell cycle GO:0045787 140 0.020
blastoderm segmentation GO:0007350 2 0.020
humoral immune response GO:0006959 49 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.020
glycosyl compound catabolic process GO:1901658 413 0.020
viral process GO:0016032 146 0.020
release of sequestered calcium ion into cytosol GO:0051209 41 0.020
regulation of cellular component biogenesis GO:0044087 281 0.019
neurogenesis GO:0022008 169 0.019
positive regulation of viral transcription GO:0050434 13 0.019
glucose homeostasis GO:0042593 31 0.019
nucleotide catabolic process GO:0009166 408 0.019
wound healing GO:0042060 115 0.019
interleukin 8 production GO:0032637 51 0.019
regulation of antimicrobial humoral response GO:0002759 1 0.019
cell projection organization GO:0030030 252 0.019
negative regulation of neuron death GO:1901215 32 0.019
i kappab kinase nf kappab signaling GO:0007249 166 0.019
regulation of dna metabolic process GO:0051052 153 0.019
regulation of nucleotide metabolic process GO:0006140 269 0.019
regulation of ossification GO:0030278 58 0.019
developmental growth GO:0048589 48 0.019
erythrocyte development GO:0048821 3 0.018
actin mediated cell contraction GO:0070252 12 0.018
positive regulation of multi organism process GO:0043902 56 0.018
purine ribonucleoside catabolic process GO:0046130 398 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.018
regulation of neural precursor cell proliferation GO:2000177 4 0.018
morphogenesis of embryonic epithelium GO:0016331 4 0.018
immune response GO:0006955 307 0.018
actin filament based movement GO:0030048 17 0.018
purine nucleobase biosynthetic process GO:0009113 3 0.018
positive regulation of nucleotide catabolic process GO:0030813 185 0.018
cellular carbohydrate metabolic process GO:0044262 84 0.018
neuron projection morphogenesis GO:0048812 50 0.018
purine ribonucleotide catabolic process GO:0009154 404 0.018
regulation of cellular component size GO:0032535 82 0.018
g1 s transition of mitotic cell cycle GO:0000082 78 0.018
positive regulation of viral process GO:0048524 37 0.017
positive regulation of autophagy GO:0010508 24 0.017
regulation of cellular amino acid metabolic process GO:0006521 6 0.017
myotube differentiation GO:0014902 22 0.017
anion transport GO:0006820 161 0.017
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.017
oocyte development GO:0048599 1 0.017
skeletal muscle organ development GO:0060538 26 0.017
cell type specific apoptotic process GO:0097285 125 0.017
Mouse
peptide transport GO:0015833 74 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.017
reactive oxygen species metabolic process GO:0072593 75 0.017
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.017
b cell activation GO:0042113 33 0.017
regulation of cell cycle phase transition GO:1901987 126 0.017
positive regulation of protein complex assembly GO:0031334 86 0.016
negative regulation of cell fate commitment GO:0010454 3 0.016
determination of bilateral symmetry GO:0009855 15 0.016
regulation of skeletal muscle tissue development GO:0048641 15 0.016
muscle fiber development GO:0048747 16 0.016
positive regulation of nucleoside metabolic process GO:0045979 186 0.016
developmental process involved in reproduction GO:0003006 66 0.016
amide transport GO:0042886 76 0.016
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.016
modulation of transcription in other organism involved in symbiotic interaction GO:0052312 20 0.016
gtp catabolic process GO:0006184 237 0.016
cell cycle checkpoint GO:0000075 117 0.016
segmentation GO:0035282 4 0.016

ATF4 disease predictions

Disease DO term ID Size Probability Func Analog Org
neuromuscular disease DOID:440 38 0.056
nervous system disease DOID:863 431 0.056
neuropathy DOID:870 52 0.056
central nervous system disease DOID:331 186 0.033
disease of metabolism DOID:0014667 295 0.026
inherited metabolic disorder DOID:655 242 0.026