Homo sapiens

0 known processes

ATG12

ATG12 autophagy related 12 homolog (S. cerevisiae)

(Aliases: APG12L,FBR93,APG12,HAPG12)

ATG12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
c terminal protein amino acid modification GO:0018410 1 0.994
Yeast
macroautophagy GO:0016236 39 0.985
Yeast Mouse Fly
multi organism metabolic process GO:0044033 41 0.897
cellular response to nutrient levels GO:0031669 69 0.896
Yeast Mouse Fly
interspecies interaction between organisms GO:0044419 156 0.882
vasodilation GO:0042311 4 0.847
autophagy GO:0006914 88 0.842
Yeast Mouse Fly
lipoprotein biosynthetic process GO:0042158 33 0.737
Yeast
multi organism cellular process GO:0044764 156 0.735
protein ubiquitination GO:0016567 314 0.715
regulation of autophagy GO:0010506 52 0.700
response to biotic stimulus GO:0009607 276 0.692
viral process GO:0016032 146 0.657
viral life cycle GO:0019058 132 0.642
cellular component assembly involved in morphogenesis GO:0010927 73 0.617
Worm
protein modification by small protein conjugation GO:0032446 342 0.614
autophagic vacuole assembly GO:0000045 19 0.590
Yeast Mouse
vacuole organization GO:0007033 44 0.566
Yeast Mouse
response to other organism GO:0051707 261 0.562
viral genome replication GO:0019079 50 0.556
membrane organization GO:0061024 292 0.556
Yeast
response to external biotic stimulus GO:0043207 261 0.545
oogenesis GO:0048477 2 0.501
regulation of cellular amino acid metabolic process GO:0006521 6 0.498
positive regulation of mucus secretion GO:0070257 1 0.482
cellular response to external stimulus GO:0071496 111 0.481
Yeast Mouse Fly
single organism membrane organization GO:0044802 268 0.427
Yeast
heart development GO:0007507 95 0.404
regulation of cilium assembly GO:1902017 6 0.402
cilium assembly GO:0042384 63 0.389
negative regulation of cell death GO:0060548 345 0.383
negative regulation of histone acetylation GO:0035067 6 0.362
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.361
negative regulation of cellular amine metabolic process GO:0033239 3 0.327
response to starvation GO:0042594 59 0.313
Yeast Mouse Fly
sequestering of calcium ion GO:0051208 17 0.304
cellular amine metabolic process GO:0044106 41 0.293
cytoplasmic transport GO:0016482 379 0.285
Yeast
cellular response to extracellular stimulus GO:0031668 72 0.279
Yeast Mouse Fly
response to bacterium GO:0009617 144 0.274
positive regulation of autophagy GO:0010508 24 0.272
protein secretion GO:0009306 98 0.256
response to nutrient levels GO:0031667 81 0.253
Yeast Mouse Fly
cellular metal ion homeostasis GO:0006875 146 0.247
determination of adult lifespan GO:0008340 2 0.230
Worm
cellular chemical homeostasis GO:0055082 180 0.229
intracellular protein transport GO:0006886 270 0.227
Yeast
amine metabolic process GO:0009308 44 0.223
calcium ion homeostasis GO:0055074 122 0.221
cell development GO:0048468 328 0.215
Worm Fly
cellular response to starvation GO:0009267 58 0.213
Yeast Mouse Fly
organelle assembly GO:0070925 176 0.205
Yeast Mouse Worm
cellular amino acid metabolic process GO:0006520 116 0.200
negative regulation of protein metabolic process GO:0051248 391 0.193
muscle structure development GO:0061061 98 0.190
Worm
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.189
regulation of cytokine secretion involved in immune response GO:0002739 7 0.186
blood vessel remodeling GO:0001974 2 0.184
calcium ion transport GO:0006816 147 0.175
protein lipidation GO:0006497 33 0.171
Yeast
cellular ion homeostasis GO:0006873 168 0.162
regulation of cellular component biogenesis GO:0044087 281 0.158
cytosolic calcium ion homeostasis GO:0051480 89 0.156
regulation of intracellular transport GO:0032386 195 0.152
cellular divalent inorganic cation homeostasis GO:0072503 128 0.143
female gamete generation GO:0007292 2 0.143
cytokine production GO:0001816 247 0.141
inner ear development GO:0048839 8 0.139
cellular calcium ion homeostasis GO:0006874 117 0.131
secretion GO:0046903 254 0.130
regulation of protein transport GO:0051223 213 0.126
negative regulation of programmed cell death GO:0043069 321 0.122
divalent metal ion transport GO:0070838 152 0.121
negative regulation of cellular protein metabolic process GO:0032269 353 0.120
regulation of homeostatic process GO:0032844 121 0.117
cation homeostasis GO:0055080 189 0.117
cellular ketone metabolic process GO:0042180 80 0.115
regulation of metal ion transport GO:0010959 120 0.115
protein targeting GO:0006605 187 0.112
Yeast
viral rna genome replication GO:0039694 9 0.111
metal ion homeostasis GO:0055065 169 0.108
cytokine secretion involved in immune response GO:0002374 7 0.107
regulation of cellular ketone metabolic process GO:0010565 50 0.107
single organism cellular localization GO:1902580 332 0.106
Yeast
regulation of reactive oxygen species metabolic process GO:2000377 41 0.105
striated muscle cell differentiation GO:0051146 43 0.103
Worm
cytokine production involved in immune response GO:0002367 27 0.102
cardiovascular system development GO:0072358 262 0.101
metal ion transport GO:0030001 272 0.099
myosin filament assembly GO:0031034 2 0.096
Worm
protein localization to organelle GO:0033365 280 0.096
Yeast
regulation of calcium ion transport into cytosol GO:0010522 33 0.094
regulation of immune response GO:0050776 201 0.092
cellular macromolecular complex assembly GO:0034622 324 0.092
Worm
regulation of defense response GO:0031347 154 0.090
establishment of protein localization to organelle GO:0072594 172 0.089
Yeast
muscle cell differentiation GO:0042692 63 0.087
Worm
response to fungus GO:0009620 4 0.087
growth GO:0040007 202 0.085
Worm
immune response GO:0006955 307 0.082
heart process GO:0003015 62 0.080
regulation of body fluid levels GO:0050878 99 0.076
system process GO:0003008 349 0.074
regulation of cellular response to stress GO:0080135 244 0.073
heart contraction GO:0060047 62 0.072
regulation of chromosome organization GO:0033044 103 0.070
regulation of protein localization GO:0032880 296 0.069
immune effector process GO:0002252 159 0.067
ventricular cardiac muscle cell differentiation GO:0055012 1 0.067
cilium morphogenesis GO:0060271 75 0.066
defense response to gram positive bacterium GO:0050830 29 0.065
positive regulation of catabolic process GO:0009896 310 0.063
protein acylation GO:0043543 138 0.063
circulatory system process GO:0003013 113 0.062
ion homeostasis GO:0050801 230 0.061
defense response to virus GO:0051607 71 0.061
cilium organization GO:0044782 68 0.061
defense response GO:0006952 315 0.060
anatomical structure formation involved in morphogenesis GO:0048646 284 0.060
Worm
divalent inorganic cation transport GO:0072511 158 0.059
chemical homeostasis GO:0048878 306 0.058
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.058
glycosyl compound catabolic process GO:1901658 413 0.058
cardiocyte differentiation GO:0035051 23 0.058
regulation of protein ubiquitination GO:0031396 95 0.058
purine ribonucleoside metabolic process GO:0046128 437 0.058
vascular process in circulatory system GO:0003018 29 0.056
mitotic cell cycle process GO:1903047 286 0.055
atp metabolic process GO:0046034 176 0.055
purine nucleoside catabolic process GO:0006152 398 0.055
cell projection assembly GO:0030031 126 0.054
multicellular organismal aging GO:0010259 3 0.054
Worm
negative regulation of chromosome organization GO:2001251 48 0.054
regulation of secretion GO:0051046 194 0.053
histone h4 k16 acetylation GO:0043984 14 0.053
protein targeting to vacuole GO:0006623 8 0.052
Yeast
negative regulation of protein modification process GO:0031400 200 0.050
regulation of ion transport GO:0043269 189 0.050
positive regulation of transport GO:0051050 336 0.048
internal protein amino acid acetylation GO:0006475 101 0.048
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.048
negative regulation of histone modification GO:0031057 19 0.047
regulation of protein catabolic process GO:0042176 155 0.046
negative regulation of organelle organization GO:0010639 126 0.045
organophosphate catabolic process GO:0046434 430 0.045
purine ribonucleoside catabolic process GO:0046130 398 0.045
peptidyl lysine acetylation GO:0018394 101 0.044
regulation of blood vessel size GO:0050880 18 0.042
anterograde axon cargo transport GO:0008089 1 0.042
cellular protein complex assembly GO:0043623 188 0.042
Worm
cell projection organization GO:0030030 252 0.041
lipoprotein metabolic process GO:0042157 42 0.041
Yeast
negative regulation of sequestering of calcium ion GO:0051283 41 0.040
calcium ion transport into cytosol GO:0060402 48 0.040
histone modification GO:0016570 251 0.040
regulation of tube size GO:0035150 18 0.040
negative regulation of protein ubiquitination GO:0031397 35 0.040
regulation of sequestering of calcium ion GO:0051282 41 0.039
sequestering of metal ion GO:0051238 24 0.038
negative regulation of protein acetylation GO:1901984 11 0.038
cytokine secretion GO:0050663 64 0.038
ossification GO:0001503 121 0.038
protein localization to vacuole GO:0072665 11 0.038
Yeast
negative regulation of peptidyl lysine acetylation GO:2000757 8 0.038
internal peptidyl lysine acetylation GO:0018393 97 0.037
nucleoside triphosphate metabolic process GO:0009141 422 0.036
purine containing compound catabolic process GO:0072523 411 0.036
aggrephagy GO:0035973 1 0.036
cellular component morphogenesis GO:0032989 314 0.036
Worm
ribonucleoside monophosphate catabolic process GO:0009158 158 0.036
striated muscle myosin thick filament assembly GO:0071688 2 0.035
Worm
positive regulation of secretion GO:0051047 116 0.035
response to endoplasmic reticulum stress GO:0034976 49 0.035
covalent chromatin modification GO:0016569 254 0.035
ribonucleoside catabolic process GO:0042454 406 0.034
lipid metabolic process GO:0006629 381 0.034
myosin filament organization GO:0031033 2 0.034
Worm
regulation of cytokine production GO:0001817 232 0.034
purine nucleotide catabolic process GO:0006195 405 0.034
ribonucleoside triphosphate metabolic process GO:0009199 412 0.034
regulation of anatomical structure size GO:0090066 101 0.034
regulation of dna metabolic process GO:0051052 153 0.033
regulation of chromatin organization GO:1902275 56 0.033
positive regulation of dna metabolic process GO:0051054 73 0.033
regulation of secretion by cell GO:1903530 177 0.033
regulation of establishment of protein localization GO:0070201 242 0.033
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.033
negative regulation of homeostatic process GO:0032845 59 0.032
divalent inorganic cation homeostasis GO:0072507 136 0.032
regulation of cell projection organization GO:0031344 107 0.032
regulation of cell projection assembly GO:0060491 47 0.032
regulation of protein secretion GO:0050708 86 0.032
defense response to bacterium GO:0042742 63 0.032
rna interference GO:0016246 4 0.031
regulation of calcium ion transport GO:0051924 79 0.031
defense response to other organism GO:0098542 129 0.031
response to oxygen levels GO:0070482 100 0.030
cell projection morphogenesis GO:0048858 129 0.030
cardiac muscle cell differentiation GO:0055007 15 0.028
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.028
regulation of cytokine production involved in immune response GO:0002718 22 0.028
regeneration GO:0031099 4 0.028
spermatid development GO:0007286 4 0.028
regulation of protein acetylation GO:1901983 25 0.027
ribonucleotide catabolic process GO:0009261 405 0.027
regulation of cytokine secretion GO:0050707 57 0.027
vacuolar transport GO:0007034 34 0.026
Yeast
ribonucleoside triphosphate catabolic process GO:0009203 391 0.026
regulation of purine nucleotide metabolic process GO:1900542 264 0.026
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.026
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.026
regulation of mucus secretion GO:0070255 1 0.025
purine ribonucleotide catabolic process GO:0009154 404 0.025
histone acetylation GO:0016573 93 0.025
regulation of response to nutrient levels GO:0032107 22 0.025
response to extracellular stimulus GO:0009991 85 0.025
Yeast Mouse Fly
protein acetylation GO:0006473 116 0.025
negative regulation of chromatin modification GO:1903309 21 0.025
regulation of response to external stimulus GO:0032101 222 0.024
negative regulation of cellular component organization GO:0051129 235 0.024
hard palate development GO:0060022 1 0.024
cellular macromolecule catabolic process GO:0044265 380 0.024
rna splicing GO:0008380 131 0.023
multi organism reproductive process GO:0044703 54 0.023
regulation of peptidyl lysine acetylation GO:2000756 22 0.023
regulation of proteolysis GO:0030162 293 0.023
carbohydrate derivative biosynthetic process GO:1901137 207 0.023
response to abiotic stimulus GO:0009628 336 0.023
actin filament based process GO:0030029 224 0.023
Worm
regulation of purine nucleotide catabolic process GO:0033121 205 0.022
striated muscle cell development GO:0055002 27 0.022
Worm
endomembrane system organization GO:0010256 196 0.022
regulation of cellular protein catabolic process GO:1903362 96 0.022
positive regulation of cell proliferation GO:0008284 301 0.021
regulation of defense response to virus GO:0050688 33 0.021
cell morphogenesis GO:0000902 296 0.021
innate immune response GO:0045087 178 0.021
cellular response to dna damage stimulus GO:0006974 379 0.021
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.020
regulation of telomere maintenance GO:0032204 13 0.020
nucleoside triphosphate catabolic process GO:0009143 394 0.020
nucleotide catabolic process GO:0009166 408 0.020
spliceosomal complex assembly GO:0000245 17 0.020
alditol phosphate metabolic process GO:0052646 3 0.020
negative regulation of apoptotic process GO:0043066 316 0.020
regulation of histone acetylation GO:0035065 19 0.019
purine nucleoside monophosphate metabolic process GO:0009126 186 0.019
response to drug GO:0042493 81 0.019
positive regulation of programmed cell death GO:0043068 249 0.019
secretion by cell GO:0032940 226 0.019
maintenance of location GO:0051235 112 0.019
protein catabolic process GO:0030163 325 0.018
apoptotic signaling pathway GO:0097190 268 0.018
chromatin organization GO:0006325 351 0.018
telomere organization GO:0032200 33 0.018
rna splicing via transesterification reactions GO:0000375 90 0.018
regulation of ion homeostasis GO:2000021 73 0.018
gamete generation GO:0007276 25 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.018
purine nucleoside triphosphate catabolic process GO:0009146 392 0.018
glycerophospholipid metabolic process GO:0006650 84 0.018
regulation of cell cycle phase transition GO:1901987 126 0.017
nucleoside phosphate catabolic process GO:1901292 412 0.017
regulation of nucleotide catabolic process GO:0030811 205 0.017
regulation of immune effector process GO:0002697 91 0.017
cytosolic calcium ion transport GO:0060401 48 0.017
regulation of meiotic cell cycle GO:0051445 4 0.017
nucleoside catabolic process GO:0009164 408 0.017
post embryonic development GO:0009791 2 0.017
Fly
lipid transport GO:0006869 90 0.017
regulation of anatomical structure morphogenesis GO:0022603 286 0.017
production of molecular mediator of immune response GO:0002440 37 0.017
reactive oxygen species metabolic process GO:0072593 75 0.017
nucleoside monophosphate catabolic process GO:0009125 159 0.017
endocytosis GO:0006897 159 0.016
blood circulation GO:0008015 113 0.016
organophosphate biosynthetic process GO:0090407 163 0.016
regulation of mitotic cell cycle phase transition GO:1901990 118 0.016
cellular response to oxygen levels GO:0071453 55 0.016
inner ear morphogenesis GO:0042472 4 0.016
body fluid secretion GO:0007589 9 0.016
cellular homeostasis GO:0019725 196 0.016
cell part morphogenesis GO:0032990 137 0.016
positive regulation of chromosome organization GO:2001252 41 0.016
regulation of nucleoside metabolic process GO:0009118 209 0.015
glycerolipid metabolic process GO:0046486 107 0.015
ribonucleoside monophosphate metabolic process GO:0009161 187 0.015
positive regulation of hydrolase activity GO:0051345 331 0.015
ear development GO:0043583 14 0.015
nuclear division GO:0000280 128 0.015
vesicle mediated transport GO:0016192 371 0.015
reproductive process GO:0022414 106 0.015
sensory organ development GO:0007423 52 0.015
regulation of cytoplasmic transport GO:1903649 149 0.015
positive regulation of organelle organization GO:0010638 195 0.014
purine nucleoside monophosphate catabolic process GO:0009128 158 0.014
establishment of protein localization to vacuole GO:0072666 8 0.014
Yeast
mrna processing GO:0006397 133 0.014
cellular amino acid biosynthetic process GO:0008652 30 0.014
cell division GO:0051301 168 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.014
spermatid differentiation GO:0048515 4 0.013
microtubule cytoskeleton organization GO:0000226 176 0.013
regulation of meiosis GO:0040020 3 0.013
neuron development GO:0048666 113 0.013
atp catabolic process GO:0006200 157 0.013
cell cycle checkpoint GO:0000075 117 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.013
histone h4 acetylation GO:0043967 47 0.013
regulation of nucleotide metabolic process GO:0006140 269 0.013
chromatin modification GO:0016568 298 0.013
positive regulation of response to extracellular stimulus GO:0032106 14 0.012
negative regulation of phosphate metabolic process GO:0045936 267 0.012
striated muscle tissue development GO:0014706 59 0.012
positive regulation of cell size GO:0045793 3 0.012
regulation of cell cycle process GO:0010564 266 0.012
microtubule based process GO:0007017 210 0.012
positive regulation of homeostatic process GO:0032846 47 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
negative regulation of growth GO:0045926 97 0.012
regulation of rna splicing GO:0043484 62 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
negative regulation of catabolic process GO:0009895 104 0.012
regulation of phosphatase activity GO:0010921 81 0.012
purine nucleoside triphosphate metabolic process GO:0009144 412 0.012
actin cytoskeleton organization GO:0030036 207 0.012
Worm
regulation of histone modification GO:0031056 47 0.012
cellular response to hyperoxia GO:0071455 4 0.012
alternative mrna splicing via spliceosome GO:0000380 27 0.011
rna processing GO:0006396 255 0.011
cardiac muscle tissue development GO:0048738 39 0.011
regulation of protein complex assembly GO:0043254 147 0.011
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
meiosis i GO:0007127 4 0.011
negative regulation of cell cycle process GO:0010948 121 0.011
positive regulation of cellular component organization GO:0051130 376 0.011
plasma membrane organization GO:0007009 115 0.011
muscle tissue development GO:0060537 62 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
protein stabilization GO:0050821 64 0.011
receptor mediated endocytosis GO:0006898 84 0.011
membrane lipid metabolic process GO:0006643 53 0.011
regulation of cell morphogenesis GO:0022604 153 0.011
axon cargo transport GO:0008088 2 0.010
cellular lipid metabolic process GO:0044255 303 0.010
rna replication GO:0039703 9 0.010
regulation of proteasomal protein catabolic process GO:0061136 87 0.010
organonitrogen compound biosynthetic process GO:1901566 200 0.010

ATG12 disease predictions

Disease DO term ID Size Probability Func Analog Org
gastrointestinal system disease DOID:77 36 0.268
intestinal disease DOID:5295 14 0.268
inflammatory bowel disease DOID:0050589 9 0.068
cancer DOID:162 167 0.030
disease of cellular proliferation DOID:14566 174 0.030
breast cancer DOID:1612 21 0.016
thoracic cancer DOID:5093 21 0.016
organ system cancer DOID:0050686 164 0.016
central nervous system disease DOID:331 186 0.014
brain disease DOID:936 73 0.014
nervous system disease DOID:863 431 0.014