Homo sapiens

53 known processes

ATG4B

ATG4 autophagy related 4 homolog B (S. cerevisiae)

(Aliases: MGC1353,APG4B,AUTL1)

ATG4B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of autophagy GO:0010508 24 0.566
macroautophagy GO:0016236 39 0.440
post embryonic development GO:0009791 2 0.394
autophagic vacuole assembly GO:0000045 19 0.242
multicellular organismal aging GO:0010259 3 0.195
determination of adult lifespan GO:0008340 2 0.192
negative regulation of axonogenesis GO:0050771 4 0.181
positive regulation of catabolic process GO:0009896 310 0.159
ras protein signal transduction GO:0007265 73 0.157
positive regulation of cellular catabolic process GO:0031331 284 0.156
protein catabolic process GO:0030163 325 0.141
regeneration GO:0031099 4 0.137
growth GO:0040007 202 0.135
regulation of cellular amino acid metabolic process GO:0006521 6 0.134
cellular amine metabolic process GO:0044106 41 0.123
regulation of cellular response to stress GO:0080135 244 0.114
regulation of cellular amine metabolic process GO:0033238 11 0.111
rab protein signal transduction GO:0032482 4 0.105
protein autophosphorylation GO:0046777 123 0.100
regulation of autophagy GO:0010506 52 0.092
collateral sprouting GO:0048668 2 0.090
amine metabolic process GO:0009308 44 0.089
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.087
oogenesis GO:0048477 2 0.087
response to biotic stimulus GO:0009607 276 0.077
developmental growth involved in morphogenesis GO:0060560 23 0.075
negative regulation of protein metabolic process GO:0051248 391 0.072
protein ubiquitination GO:0016567 314 0.072
regulation of cell differentiation GO:0045595 393 0.068
cell morphogenesis GO:0000902 296 0.066
cellular amino acid metabolic process GO:0006520 116 0.064
negative regulation of cell death GO:0060548 345 0.061
purine ribonucleoside metabolic process GO:0046128 437 0.060
regulation of transferase activity GO:0051338 355 0.060
regulation of neurotrophin trk receptor signaling pathway GO:0051386 2 0.059
single organism membrane organization GO:0044802 268 0.059
Yeast
regulation of cell morphogenesis GO:0022604 153 0.058
nervous system development GO:0007399 293 0.056
regulation of collateral sprouting GO:0048670 2 0.056
cerebellum development GO:0021549 2 0.056
positive regulation of protein phosphorylation GO:0001934 313 0.055
negative regulation of cellular component organization GO:0051129 235 0.054
response to starvation GO:0042594 59 0.052
defense response to other organism GO:0098542 129 0.052
cell growth GO:0016049 160 0.051
nucleoside phosphate catabolic process GO:1901292 412 0.051
cellular ketone metabolic process GO:0042180 80 0.050
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.047
positive regulation of cellular amine metabolic process GO:0033240 7 0.047
taxis GO:0042330 157 0.046
response to extracellular stimulus GO:0009991 85 0.044
protein modification by small protein conjugation GO:0032446 342 0.044
female gamete generation GO:0007292 2 0.043
compound eye development GO:0048749 1 0.042
memory GO:0007613 3 0.041
mapk cascade GO:0000165 288 0.041
autophagy GO:0006914 88 0.041
positive regulation of phosphorylation GO:0042327 394 0.041
cellular macromolecule catabolic process GO:0044265 380 0.040
negative regulation of cell growth GO:0030308 83 0.040
negative regulation of programmed cell death GO:0043069 321 0.039
cellular component morphogenesis GO:0032989 314 0.039
embryo development GO:0009790 123 0.038
cytoplasmic transport GO:0016482 379 0.038
Yeast
negative regulation of transferase activity GO:0051348 124 0.038
negative regulation of organelle organization GO:0010639 126 0.038
tube development GO:0035295 125 0.038
microtubule based process GO:0007017 210 0.038
vacuole organization GO:0007033 44 0.038
neuron projection regeneration GO:0031102 1 0.037
regulation of protein kinase activity GO:0045859 289 0.037
signal transduction by phosphorylation GO:0023014 297 0.037
negative regulation of developmental process GO:0051093 247 0.037
positive regulation of cell death GO:0010942 263 0.036
regulation of kinase activity GO:0043549 314 0.036
response to other organism GO:0051707 261 0.036
regulation of protein binding GO:0043393 66 0.035
regulation of anatomical structure size GO:0090066 101 0.035
purine nucleoside triphosphate metabolic process GO:0009144 412 0.035
regulation of anatomical structure morphogenesis GO:0022603 286 0.034
system process GO:0003008 349 0.034
cellular component disassembly GO:0022411 92 0.033
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.033
single organism cellular localization GO:1902580 332 0.033
Yeast
anatomical structure formation involved in morphogenesis GO:0048646 284 0.032
positive regulation of developmental process GO:0051094 314 0.032
cellular response to external stimulus GO:0071496 111 0.032
cellular response to extracellular stimulus GO:0031668 72 0.031
vesicle mediated transport GO:0016192 371 0.031
cell projection morphogenesis GO:0048858 129 0.031
regulation of growth GO:0040008 165 0.031
regulation of cellular ketone metabolic process GO:0010565 50 0.031
cellular response to nutrient levels GO:0031669 69 0.031
covalent chromatin modification GO:0016569 254 0.031
hindbrain development GO:0030902 3 0.030
apoptotic signaling pathway GO:0097190 268 0.030
regulation of neurogenesis GO:0050767 82 0.030
negative regulation of cellular amine metabolic process GO:0033239 3 0.029
actin filament organization GO:0007015 128 0.029
positive regulation of response to extracellular stimulus GO:0032106 14 0.029
regulation of response to external stimulus GO:0032101 222 0.028
response to external biotic stimulus GO:0043207 261 0.028
organelle fission GO:0048285 149 0.028
generation of neurons GO:0048699 152 0.028
cell morphogenesis involved in differentiation GO:0000904 144 0.028
regulation of cellular response to growth factor stimulus GO:0090287 76 0.028
apoptotic mitochondrial changes GO:0008637 57 0.028
negative regulation of cellular protein metabolic process GO:0032269 353 0.027
negative regulation of cell motility GO:2000146 104 0.027
cell development GO:0048468 328 0.027
protein acetylation GO:0006473 116 0.026
cellular protein catabolic process GO:0044257 261 0.026
extrinsic apoptotic signaling pathway GO:0097191 119 0.026
positive regulation of apoptotic process GO:0043065 246 0.026
positive regulation of cell motility GO:2000147 177 0.026
positive regulation of nucleotide catabolic process GO:0030813 185 0.026
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.025
regulation of mapk cascade GO:0043408 262 0.025
neurogenesis GO:0022008 169 0.025
atp metabolic process GO:0046034 176 0.025
purine nucleoside triphosphate catabolic process GO:0009146 392 0.025
head development GO:0060322 108 0.025
small gtpase mediated signal transduction GO:0007264 78 0.024
receptor internalization GO:0031623 43 0.024
response to inorganic substance GO:0010035 127 0.024
regulation of locomotion GO:0040012 329 0.024
proteasomal protein catabolic process GO:0010498 176 0.024
protein oligomerization GO:0051259 173 0.023
regulation of gtp catabolic process GO:0033124 180 0.023
protein complex disassembly GO:0043241 52 0.023
positive regulation of kinase activity GO:0033674 204 0.023
regulation of purine nucleotide catabolic process GO:0033121 205 0.023
regulation of protein serine threonine kinase activity GO:0071900 179 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.022
negative regulation of protein processing GO:0010955 142 0.022
positive regulation of locomotion GO:0040017 186 0.022
defense response to bacterium GO:0042742 63 0.022
regulation of membrane permeability GO:0090559 25 0.022
organelle assembly GO:0070925 176 0.022
positive regulation of programmed cell death GO:0043068 249 0.022
regulation of proteolysis GO:0030162 293 0.021
cellular response to starvation GO:0009267 58 0.021
negative regulation of multicellular organismal process GO:0051241 317 0.021
regulation of cell development GO:0060284 161 0.021
regulation of defense response GO:0031347 154 0.021
positive regulation of hydrolase activity GO:0051345 331 0.021
positive regulation of protein kinase activity GO:0045860 190 0.021
positive regulation of response to external stimulus GO:0032103 88 0.021
immune system development GO:0002520 195 0.021
negative regulation of phosphorylation GO:0042326 174 0.021
protein polymerization GO:0051258 71 0.020
catecholamine secretion GO:0050432 1 0.020
lipoprotein metabolic process GO:0042157 42 0.020
Yeast
peptidyl lysine acetylation GO:0018394 101 0.020
negative regulation of phosphate metabolic process GO:0045936 267 0.020
axon extension GO:0048675 13 0.020
defense response GO:0006952 315 0.020
chromatin modification GO:0016568 298 0.020
cell projection organization GO:0030030 252 0.020
protein acylation GO:0043543 138 0.020
positive regulation of cellular component organization GO:0051130 376 0.019
positive regulation of neural precursor cell proliferation GO:2000179 2 0.019
cellular macromolecular complex assembly GO:0034622 324 0.019
actin filament capping GO:0051693 4 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.019
negative regulation of catalytic activity GO:0043086 335 0.019
response to fungus GO:0009620 4 0.019
mucus secretion GO:0070254 1 0.019
positive regulation of nucleoside metabolic process GO:0045979 186 0.019
negative regulation of kinase activity GO:0033673 106 0.018
response to nutrient levels GO:0031667 81 0.018
positive regulation of nucleotide metabolic process GO:0045981 230 0.018
embryo development ending in birth or egg hatching GO:0009792 34 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.018
mitochondrion organization GO:0007005 156 0.018
gtp metabolic process GO:0046039 239 0.018
negative regulation of collateral sprouting GO:0048671 1 0.018
mitochondrial membrane organization GO:0007006 40 0.018
ribonucleoside triphosphate metabolic process GO:0009199 412 0.018
organelle localization GO:0051640 84 0.018
positive regulation of transferase activity GO:0051347 227 0.017
response to virus GO:0009615 126 0.017
actin filament based process GO:0030029 224 0.017
positive regulation of synaptic transmission GO:0050806 4 0.017
regulation of binding GO:0051098 111 0.017
regulation of membrane potential GO:0042391 95 0.017
regulation of cell migration GO:0030334 289 0.017
regulation of protein catabolic process GO:0042176 155 0.017
activation of protein kinase activity GO:0032147 90 0.017
erythrocyte development GO:0048821 3 0.017
peptidyl lysine modification GO:0018205 144 0.017
response to hyperoxia GO:0055093 4 0.017
purine containing compound catabolic process GO:0072523 411 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.017
regulation of cell motility GO:2000145 299 0.017
regulation of cellular component size GO:0032535 82 0.017
maintenance of location GO:0051235 112 0.016
chromatin organization GO:0006325 351 0.016
somatic muscle development GO:0007525 1 0.016
regulation of stress activated mapk cascade GO:0032872 84 0.016
nucleoside phosphate biosynthetic process GO:1901293 109 0.016
positive regulation of mitochondrial membrane permeability GO:0035794 17 0.016
myeloid cell homeostasis GO:0002262 34 0.016
chemotaxis GO:0006935 157 0.016
negative regulation of protein phosphorylation GO:0001933 140 0.016
negative regulation of apoptotic process GO:0043066 316 0.016
gtp catabolic process GO:0006184 237 0.016
nucleoside triphosphate metabolic process GO:0009141 422 0.016
cell part morphogenesis GO:0032990 137 0.016
brain development GO:0007420 97 0.016
response to bacterium GO:0009617 144 0.016
cytoskeleton dependent intracellular transport GO:0030705 21 0.016
i kappab kinase nf kappab signaling GO:0007249 166 0.016
negative regulation of locomotion GO:0040013 118 0.016
convergent extension GO:0060026 1 0.016
oocyte development GO:0048599 1 0.016
defense response to gram positive bacterium GO:0050830 29 0.015
protein localization to organelle GO:0033365 280 0.015
Yeast
blood vessel development GO:0001568 172 0.015
tube morphogenesis GO:0035239 95 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.015
regulation of neuron differentiation GO:0045664 70 0.015
organophosphate biosynthetic process GO:0090407 163 0.015
regulation of nervous system development GO:0051960 88 0.015
muscle cell differentiation GO:0042692 63 0.015
regulation of chromosome organization GO:0033044 103 0.015
regulation of cellular component movement GO:0051270 334 0.015
negative regulation of proteolysis GO:0045861 132 0.015
intrinsic apoptotic signaling pathway GO:0097193 127 0.015
developmental growth GO:0048589 48 0.015
lipoprotein biosynthetic process GO:0042158 33 0.014
Yeast
regulation of protein complex assembly GO:0043254 147 0.014
positive regulation of cell differentiation GO:0045597 211 0.014
guanosine containing compound metabolic process GO:1901068 244 0.014
response to axon injury GO:0048678 1 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.014
negative regulation of protein maturation GO:1903318 142 0.014
positive regulation of transcription during mitosis GO:0045897 2 0.014
secretion by cell GO:0032940 226 0.014
macromolecular complex disassembly GO:0032984 60 0.014
positive regulation of necrotic cell death GO:0010940 4 0.014
regulation of map kinase activity GO:0043405 108 0.014
developmental programmed cell death GO:0010623 3 0.014
regulation of neuron projection development GO:0010975 57 0.014
mitotic nuclear division GO:0007067 119 0.014
response to hormone GO:0009725 175 0.014
regulation of cellular protein catabolic process GO:1903362 96 0.014
defense response to virus GO:0051607 71 0.014
positive regulation of macroautophagy GO:0016239 12 0.014
regulation of cell projection organization GO:0031344 107 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.014
response to decreased oxygen levels GO:0036293 96 0.013
nucleoside catabolic process GO:0009164 408 0.013
regulation of cellular component biogenesis GO:0044087 281 0.013
ribonucleotide biosynthetic process GO:0009260 81 0.013
mitochondrial transport GO:0006839 60 0.013
regulation of synaptic transmission dopaminergic GO:0032225 4 0.013
actin filament based movement GO:0030048 17 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.013
regulation of actin filament polymerization GO:0030833 50 0.013
negative regulation of cell migration GO:0030336 102 0.013
purine nucleoside catabolic process GO:0006152 398 0.013
endosomal transport GO:0016197 129 0.013
regulation of nucleoside metabolic process GO:0009118 209 0.013
carbohydrate derivative biosynthetic process GO:1901137 207 0.013
regulation of extent of cell growth GO:0061387 9 0.013
positive regulation of cell development GO:0010720 92 0.013
negative regulation of neuron differentiation GO:0045665 21 0.013
regulation of protein processing GO:0070613 150 0.013
cellular response to oxygen containing compound GO:1901701 276 0.013
negative regulation of cellular component movement GO:0051271 106 0.013
erythrocyte differentiation GO:0030218 28 0.013
regulation of small gtpase mediated signal transduction GO:0051056 156 0.013
regulation of protein maturation GO:1903317 150 0.013
ribonucleoside triphosphate catabolic process GO:0009203 391 0.012
cell death in response to oxidative stress GO:0036473 29 0.012
cellular response to oxygen levels GO:0071453 55 0.012
axonogenesis GO:0007409 31 0.012
negative regulation of cell differentiation GO:0045596 171 0.012
positive regulation of gtp catabolic process GO:0033126 166 0.012
innate immune response GO:0045087 178 0.012
organonitrogen compound biosynthetic process GO:1901566 200 0.012
neurological system process GO:0050877 163 0.012
purine nucleotide catabolic process GO:0006195 405 0.012
cellular component assembly involved in morphogenesis GO:0010927 73 0.012
positive regulation of nervous system development GO:0051962 54 0.012
neuron differentiation GO:0030182 138 0.012
negative regulation of growth GO:0045926 97 0.012
positive regulation of secretion GO:0051047 116 0.012
protein localization to vacuole GO:0072665 11 0.012
Yeast
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 21 0.012
protein maturation GO:0051604 233 0.012
Yeast
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.012
adult locomotory behavior GO:0008344 1 0.012
regulation of cell growth GO:0001558 135 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
regulation of dephosphorylation GO:0035303 96 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.012
negative regulation of cell projection organization GO:0031345 22 0.012
histone modification GO:0016570 251 0.012
behavior GO:0007610 112 0.012
spermatid development GO:0007286 4 0.012
neuron projection extension GO:1990138 14 0.012
single organism reproductive process GO:0044702 98 0.011
guanosine containing compound catabolic process GO:1901069 239 0.011
regulation of cell cycle process GO:0010564 266 0.011
histone acetylation GO:0016573 93 0.011
retrograde transport endosome to golgi GO:0042147 45 0.011
purine ribonucleotide catabolic process GO:0009154 404 0.011
negative regulation of hydrogen peroxide mediated programmed cell death GO:1901299 3 0.011
response to growth factor GO:0070848 205 0.011
hemopoiesis GO:0030097 180 0.011
tissue morphogenesis GO:0048729 96 0.011
protein processing GO:0016485 226 0.011
Yeast
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.011
reproductive process GO:0022414 106 0.011
establishment of protein localization to membrane GO:0090150 121 0.011
Yeast
circulatory system development GO:0072359 262 0.011
negative regulation of protein catabolic process GO:0042177 59 0.011
cell division GO:0051301 168 0.011
positive regulation of cell projection organization GO:0031346 64 0.011
long term memory GO:0007616 2 0.011
hematopoietic or lymphoid organ development GO:0048534 186 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
segmentation GO:0035282 4 0.011
negative regulation of protein kinase activity GO:0006469 98 0.011
negative regulation of protein depolymerization GO:1901880 17 0.011
cellular response to oxidative stress GO:0034599 85 0.011
regulation of ras gtpase activity GO:0032318 128 0.011
blastoderm segmentation GO:0007350 2 0.011
cellular protein complex disassembly GO:0043624 36 0.011
dephosphorylation GO:0016311 209 0.011
cilium morphogenesis GO:0060271 75 0.011
positive regulation of cellular component movement GO:0051272 181 0.010
microtubule cytoskeleton organization GO:0000226 176 0.010
enzyme linked receptor protein signaling pathway GO:0007167 303 0.010
positive regulation of release of cytochrome c from mitochondria GO:0090200 18 0.010
nerve development GO:0021675 4 0.010
response to oxygen containing compound GO:1901700 369 0.010
epithelium development GO:0060429 227 0.010
cytokine production GO:0001816 247 0.010
brain morphogenesis GO:0048854 1 0.010
nucleotide catabolic process GO:0009166 408 0.010
regulation of oocyte development GO:0060281 1 0.010
mitotic cell cycle process GO:1903047 286 0.010

ATG4B disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.076
connective tissue disease DOID:65 109 0.076
bone disease DOID:0080001 88 0.035
bone remodeling disease DOID:0080005 26 0.031
cancer DOID:162 167 0.024
disease of cellular proliferation DOID:14566 174 0.024
organ system cancer DOID:0050686 164 0.024
cardiovascular system disease DOID:1287 106 0.024
central nervous system disease DOID:331 186 0.022
nervous system disease DOID:863 431 0.022
retinal disease DOID:5679 118 0.021
retinal degeneration DOID:8466 89 0.021
sensory system disease DOID:0050155 203 0.021
eye and adnexa disease DOID:1492 150 0.021
eye disease DOID:5614 149 0.021
hypertension DOID:10763 13 0.015
artery disease DOID:0050828 23 0.015
vascular disease DOID:178 25 0.015
essential hypertension DOID:10825 8 0.015
disease of metabolism DOID:0014667 295 0.012