Homo sapiens

0 known processes

ATP6AP1

ATPase, H+ transporting, lysosomal accessory protein 1

(Aliases: ATP6IP1,VATPS1,Ac45,XAP-3,16A,MGC129781,XAP3,ATP6S1,CF2)

ATP6AP1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vacuole organization GO:0007033 44 0.751
vesicle mediated transport GO:0016192 371 0.413
Mouse
post embryonic development GO:0009791 2 0.385
determination of adult lifespan GO:0008340 2 0.294
calcium ion transmembrane transport GO:0070588 76 0.255
cellular homeostasis GO:0019725 196 0.213
negative regulation of blood vessel remodeling GO:0060313 1 0.211
transmembrane transport GO:0055085 399 0.187
protein localization to organelle GO:0033365 280 0.186
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.182
cellular cation homeostasis GO:0030003 163 0.173
cellular ion homeostasis GO:0006873 168 0.169
regulation of cellular amine metabolic process GO:0033238 11 0.169
regulation of elastin catabolic process GO:0060310 1 0.162
ion homeostasis GO:0050801 230 0.150
Mouse
exocytosis GO:0006887 71 0.138
Mouse
inorganic ion transmembrane transport GO:0098660 231 0.131
cellular chemical homeostasis GO:0055082 180 0.126
ubiquitin dependent protein catabolic process GO:0006511 206 0.123
regulation of systemic arterial blood pressure by hormone GO:0001990 12 0.117
peripheral nervous system development GO:0007422 2 0.111
negative regulation of axonogenesis GO:0050771 4 0.102
negative regulation of cell death GO:0060548 345 0.099
cation homeostasis GO:0055080 189 0.095
Mouse
cellular amine metabolic process GO:0044106 41 0.095
cellular macromolecule catabolic process GO:0044265 380 0.092
cellular amide metabolic process GO:0043603 69 0.092
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.084
inorganic cation transmembrane transport GO:0098662 194 0.083
carbohydrate metabolic process GO:0005975 207 0.080
multicellular organismal aging GO:0010259 3 0.077
regulation of secretion GO:0051046 194 0.076
Mouse
secretion by cell GO:0032940 226 0.075
Mouse
cation transmembrane transport GO:0098655 238 0.074
epidermis development GO:0008544 59 0.074
single organism carbohydrate metabolic process GO:0044723 193 0.073
cellular ketone metabolic process GO:0042180 80 0.072
regulation of oxidative stress induced cell death GO:1903201 24 0.070
cell development GO:0048468 328 0.069
Mouse
response to endoplasmic reticulum stress GO:0034976 49 0.069
ion transmembrane transport GO:0034220 338 0.068
negative regulation of elastin catabolic process GO:0060311 1 0.067
cellular component morphogenesis GO:0032989 314 0.065
cellular amino acid metabolic process GO:0006520 116 0.065
metal ion homeostasis GO:0055065 169 0.063
heart morphogenesis GO:0003007 48 0.063
chemical homeostasis GO:0048878 306 0.063
Mouse
sensory perception of pain GO:0019233 4 0.062
hair cell differentiation GO:0035315 2 0.062
apoptotic signaling pathway GO:0097190 268 0.059
amine metabolic process GO:0009308 44 0.059
locomotory behavior GO:0007626 1 0.058
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.058
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.058
oxidation reduction process GO:0055114 396 0.058
female gamete generation GO:0007292 2 0.057
negative regulation of cellular component organization GO:0051129 235 0.056
epithelium development GO:0060429 227 0.056
Zebrafish
eye development GO:0001654 42 0.055
Zebrafish
neuron differentiation GO:0030182 138 0.055
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.055
camera type eye development GO:0043010 25 0.054
Zebrafish
carbohydrate catabolic process GO:0016052 36 0.052
regulation of cellular amino acid metabolic process GO:0006521 6 0.051
regulation of secretion by cell GO:1903530 177 0.050
Mouse
regulation of mapk cascade GO:0043408 262 0.050
Mouse
modification dependent macromolecule catabolic process GO:0043632 212 0.049
positive regulation of necrotic cell death GO:0010940 4 0.048
retina development in camera type eye GO:0060041 15 0.048
Zebrafish
hydrogen transport GO:0006818 23 0.048
positive regulation of cellular amine metabolic process GO:0033240 7 0.047
lipid metabolic process GO:0006629 381 0.047
response to fungus GO:0009620 4 0.046
receptor mediated endocytosis GO:0006898 84 0.045
epithelial cell differentiation GO:0030855 141 0.045
maintenance of location GO:0051235 112 0.045
cell projection organization GO:0030030 252 0.045
cellular response to reactive oxygen species GO:0034614 50 0.045
monosaccharide metabolic process GO:0005996 74 0.042
kidney development GO:0001822 53 0.042
regulation of cellular ketone metabolic process GO:0010565 50 0.042
regulation of intracellular transport GO:0032386 195 0.041
organelle assembly GO:0070925 176 0.040
ribonucleoside triphosphate metabolic process GO:0009199 412 0.039
cellular protein catabolic process GO:0044257 261 0.039
nervous system development GO:0007399 293 0.039
phospholipid metabolic process GO:0006644 99 0.038
cell morphogenesis GO:0000902 296 0.038
oogenesis GO:0048477 2 0.038
golgi vesicle transport GO:0048193 80 0.037
ph reduction GO:0045851 11 0.037
Mouse
regulation of peptidase activity GO:0052547 180 0.037
single organism membrane organization GO:0044802 268 0.036
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.036
multicellular organismal homeostasis GO:0048871 67 0.036
Mouse
intracellular protein transport GO:0006886 270 0.035
negative regulation of apoptotic process GO:0043066 316 0.035
embryonic retina morphogenesis in camera type eye GO:0060059 1 0.035
monovalent inorganic cation homeostasis GO:0055067 37 0.034
Mouse
generation of neurons GO:0048699 152 0.034
neuron development GO:0048666 113 0.033
ribonucleotide catabolic process GO:0009261 405 0.033
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.033
protein modification by small protein conjugation GO:0032446 342 0.033
proteasomal protein catabolic process GO:0010498 176 0.032
regulation of anatomical structure morphogenesis GO:0022603 286 0.032
cell morphogenesis involved in differentiation GO:0000904 144 0.032
phosphatidylinositol metabolic process GO:0046488 53 0.032
regulation of lipid metabolic process GO:0019216 96 0.032
glycerophospholipid metabolic process GO:0006650 84 0.031
cilium organization GO:0044782 68 0.031
epidermal cell differentiation GO:0009913 45 0.031
central nervous system development GO:0007417 123 0.030
cytoplasmic transport GO:0016482 379 0.030
negative regulation of collagen catabolic process GO:0010711 1 0.030
cell part morphogenesis GO:0032990 137 0.030
nucleoside catabolic process GO:0009164 408 0.030
cation transport GO:0006812 331 0.030
negative regulation of programmed cell death GO:0043069 321 0.029
cellular carbohydrate metabolic process GO:0044262 84 0.029
divalent metal ion transport GO:0070838 152 0.029
nephric duct development GO:0072176 4 0.029
wnt signaling pathway GO:0016055 156 0.028
positive regulation of wnt signaling pathway GO:0030177 54 0.028
glycoprotein metabolic process GO:0009100 110 0.028
alcohol metabolic process GO:0006066 114 0.028
modification dependent protein catabolic process GO:0019941 209 0.028
divalent inorganic cation transport GO:0072511 158 0.028
defense response GO:0006952 315 0.028
protein ubiquitination GO:0016567 314 0.028
regulation of growth GO:0040008 165 0.027
embryo development GO:0009790 123 0.027
glycolipid metabolic process GO:0006664 27 0.027
regulation of wnt signaling pathway GO:0030111 123 0.027
single organism reproductive process GO:0044702 98 0.027
purine nucleoside triphosphate catabolic process GO:0009146 392 0.026
positive regulation of secretion by cell GO:1903532 108 0.026
Mouse
microtubule based movement GO:0007018 32 0.026
regulation of blood vessel remodeling GO:0060312 2 0.026
carbohydrate derivative biosynthetic process GO:1901137 207 0.026
cellular metal ion homeostasis GO:0006875 146 0.026
generation of precursor metabolites and energy GO:0006091 68 0.026
secretion GO:0046903 254 0.026
Mouse
nucleoside triphosphate metabolic process GO:0009141 422 0.026
protein localization to endoplasmic reticulum GO:0070972 19 0.025
nerve development GO:0021675 4 0.025
neuron projection development GO:0031175 106 0.025
purine ribonucleoside metabolic process GO:0046128 437 0.025
neurological system process GO:0050877 163 0.024
mitochondrial calcium ion homeostasis GO:0051560 11 0.024
purine ribonucleoside catabolic process GO:0046130 398 0.024
organophosphate catabolic process GO:0046434 430 0.024
positive regulation of cell death GO:0010942 263 0.024
regulation of protein processing GO:0070613 150 0.024
protein localization to membrane GO:0072657 160 0.024
elastin catabolic process GO:0060309 1 0.023
muscle cell cellular homeostasis GO:0046716 3 0.023
neurogenesis GO:0022008 169 0.023
necrotic cell death GO:0070265 21 0.023
organic hydroxy compound metabolic process GO:1901615 147 0.022
regulation of proteolysis GO:0030162 293 0.022
reproductive process GO:0022414 106 0.022
regulation of establishment of protein localization GO:0070201 242 0.022
anatomical structure formation involved in morphogenesis GO:0048646 284 0.022
endocytosis GO:0006897 159 0.022
regulation of synaptic vesicle exocytosis GO:2000300 2 0.022
cellular lipid metabolic process GO:0044255 303 0.022
lipid biosynthetic process GO:0008610 177 0.022
macromolecule glycosylation GO:0043413 63 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.021
reactive oxygen species metabolic process GO:0072593 75 0.021
nucleotide catabolic process GO:0009166 408 0.021
membrane organization GO:0061024 292 0.021
protein catabolic process GO:0030163 325 0.021
head development GO:0060322 108 0.021
glycoprotein biosynthetic process GO:0009101 91 0.021
single organism cellular localization GO:1902580 332 0.021
monovalent inorganic cation transport GO:0015672 128 0.021
regulation of protein maturation GO:1903317 150 0.020
establishment of protein localization to organelle GO:0072594 172 0.020
growth GO:0040007 202 0.020
skin development GO:0043588 76 0.020
cilium assembly GO:0042384 63 0.020
negative regulation of cell development GO:0010721 48 0.020
metal ion transport GO:0030001 272 0.020
positive regulation of transport GO:0051050 336 0.020
Mouse
sensory organ development GO:0007423 52 0.020
Zebrafish
positive regulation of secretion GO:0051047 116 0.020
Mouse
atp catabolic process GO:0006200 157 0.020
neuromuscular process GO:0050905 15 0.020
neuromuscular junction development GO:0007528 3 0.020
negative regulation of cellular protein metabolic process GO:0032269 353 0.019
protein maturation GO:0051604 233 0.019
system process GO:0003008 349 0.019
regulation of cellular response to stress GO:0080135 244 0.019
negative regulation of peptidase activity GO:0010466 91 0.019
cell projection morphogenesis GO:0048858 129 0.019
glycerolipid biosynthetic process GO:0045017 51 0.018
oocyte differentiation GO:0009994 2 0.018
rab protein signal transduction GO:0032482 4 0.018
reproduction GO:0000003 63 0.018
positive regulation of phosphorylation GO:0042327 394 0.018
Mouse
embryonic morphogenesis GO:0048598 85 0.018
anterograde axon cargo transport GO:0008089 1 0.018
molting cycle GO:0042303 28 0.018
regulation of cellular ph GO:0030641 17 0.018
cell growth GO:0016049 160 0.018
organophosphate biosynthetic process GO:0090407 163 0.018
regulation of apoptotic signaling pathway GO:2001233 175 0.017
nucleoside phosphate catabolic process GO:1901292 412 0.017
regulation of endopeptidase activity GO:0052548 170 0.017
response to oxidative stress GO:0006979 121 0.017
negative regulation of multicellular organismal process GO:0051241 317 0.017
erythrocyte development GO:0048821 3 0.017
negative regulation of catalytic activity GO:0043086 335 0.017
positive regulation of cellular component organization GO:0051130 376 0.017
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.017
antigen processing and presentation GO:0019882 33 0.017
regulation of protein transport GO:0051223 213 0.017
renal system development GO:0072001 63 0.017
mapk cascade GO:0000165 288 0.017
Mouse
cardiac muscle cell contraction GO:0086003 4 0.017
regulation of protein kinase activity GO:0045859 289 0.016
positive regulation of mitochondrial calcium ion concentration GO:0051561 8 0.016
purine nucleotide catabolic process GO:0006195 405 0.016
microtubule based process GO:0007017 210 0.016
ribonucleoside catabolic process GO:0042454 406 0.016
chromatin modification GO:0016568 298 0.016
reactive nitrogen species metabolic process GO:2001057 3 0.016
vasodilation GO:0042311 4 0.016
cellular divalent inorganic cation homeostasis GO:0072503 128 0.016
single organism carbohydrate catabolic process GO:0044724 33 0.016
cellular calcium ion homeostasis GO:0006874 117 0.016
purine nucleoside monophosphate metabolic process GO:0009126 186 0.015
cell projection assembly GO:0030031 126 0.015
positive regulation of exocytosis GO:0045921 35 0.015
Mouse
reactive oxygen species biosynthetic process GO:1903409 4 0.015
memory GO:0007613 3 0.015
response to axon injury GO:0048678 1 0.015
protein glycosylation GO:0006486 62 0.015
regulation of ph GO:0006885 20 0.014
Mouse
regulation of angiotensin levels in blood GO:0002002 3 0.014
cellular monovalent inorganic cation homeostasis GO:0030004 26 0.014
positive regulation of kinase activity GO:0033674 204 0.013
positive regulation of programmed cell death GO:0043068 249 0.013
regulation of transferase activity GO:0051338 355 0.013
response to metal ion GO:0010038 84 0.013
signal transduction by phosphorylation GO:0023014 297 0.013
Mouse
response to biotic stimulus GO:0009607 276 0.013
response to starvation GO:0042594 59 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.013
maintenance of protein location GO:0045185 57 0.013
syncytium formation by plasma membrane fusion GO:0000768 2 0.013
regulation of ion transmembrane transport GO:0034765 132 0.013
epithelial cell proliferation GO:0050673 128 0.013
urogenital system development GO:0001655 65 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
purine ribonucleotide catabolic process GO:0009154 404 0.013
mating GO:0007618 1 0.013
neuron projection morphogenesis GO:0048812 50 0.013
negative regulation of protein metabolic process GO:0051248 391 0.013
hexose metabolic process GO:0019318 55 0.013
metencephalon development GO:0022037 2 0.013
cholesterol metabolic process GO:0008203 28 0.013
oocyte development GO:0048599 1 0.012
purine nucleoside triphosphate metabolic process GO:0009144 412 0.012
anatomical structure homeostasis GO:0060249 100 0.012
Mouse
divalent inorganic cation homeostasis GO:0072507 136 0.012
embryonic organ development GO:0048568 36 0.012
regulation of vesicle mediated transport GO:0060627 130 0.012
Mouse
purine containing compound catabolic process GO:0072523 411 0.012
hindbrain development GO:0030902 3 0.012
cerebral cortex radially oriented cell migration GO:0021799 1 0.012
compound eye development GO:0048749 1 0.012
response to reactive oxygen species GO:0000302 61 0.012
attachment of gpi anchor to protein GO:0016255 1 0.012
immune response GO:0006955 307 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
response to oxygen levels GO:0070482 100 0.012
calcium ion transport GO:0006816 147 0.012
blastocyst development GO:0001824 3 0.012
intrinsic apoptotic signaling pathway GO:0097193 127 0.012
g protein coupled receptor signaling pathway GO:0007186 207 0.012
regulation of intracellular ph GO:0051453 16 0.012
second messenger mediated signaling GO:0019932 78 0.011
calcium ion homeostasis GO:0055074 122 0.011
chromatin organization GO:0006325 351 0.011
gtp metabolic process GO:0046039 239 0.011
glycogen catabolic process GO:0005980 4 0.011
negative regulation of endopeptidase activity GO:0010951 84 0.011
positive regulation of organelle organization GO:0010638 195 0.011
positive regulation of intracellular transport GO:0032388 104 0.011
regulation of ion transport GO:0043269 189 0.011
midbrain development GO:0030901 45 0.011
protein stabilization GO:0050821 64 0.011
sulfur compound metabolic process GO:0006790 101 0.011
regulation of cell projection organization GO:0031344 107 0.011
cytoskeleton dependent intracellular transport GO:0030705 21 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.011
peptidyl lysine modification GO:0018205 144 0.011
regulation of blood pressure GO:0008217 30 0.011
heart contraction GO:0060047 62 0.011
small molecule biosynthetic process GO:0044283 157 0.011
protein processing GO:0016485 226 0.011
posttranscriptional regulation of gene expression GO:0010608 213 0.011
prostate gland development GO:0030850 3 0.011
cerebellum development GO:0021549 2 0.011
negative regulation of cellular response to oxidative stress GO:1900408 18 0.011
regulation of hormone levels GO:0010817 125 0.010
purine nucleoside monophosphate catabolic process GO:0009128 158 0.010
lipid modification GO:0030258 84 0.010
endocrine process GO:0050886 25 0.010
atp metabolic process GO:0046034 176 0.010
liposaccharide metabolic process GO:1903509 27 0.010
cellular component assembly involved in morphogenesis GO:0010927 73 0.010
hexose catabolic process GO:0019320 7 0.010
response to other organism GO:0051707 261 0.010
regulation of cell differentiation GO:0045595 393 0.010
Mouse
negative regulation of proteolysis GO:0045861 132 0.010

ATP6AP1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.971
inherited metabolic disorder DOID:655 242 0.971
lipid storage disease DOID:9455 28 0.575
lysosomal storage disease DOID:3211 47 0.575
cerebral degeneration DOID:1443 16 0.464
central nervous system disease DOID:331 186 0.464
brain disease DOID:936 73 0.464
nervous system disease DOID:863 431 0.464
disease of mental health DOID:150 70 0.104
neurodegenerative disease DOID:1289 102 0.088
neuronal ceroid lipofuscinosis DOID:14503 11 0.052
sensory system disease DOID:0050155 203 0.050
eye and adnexa disease DOID:1492 150 0.050
eye disease DOID:5614 149 0.050
cognitive disorder DOID:1561 29 0.030
developmental disorder of mental health DOID:0060037 29 0.019
specific developmental disorder DOID:0060038 19 0.019
intellectual disability DOID:1059 13 0.019
leukodystrophy DOID:10579 8 0.018
mucopolysaccharidosis DOID:12798 11 0.013
immune system disease DOID:2914 155 0.011
hematopoietic system disease DOID:74 100 0.011
blood protein disease DOID:620 16 0.011
carbohydrate metabolic disorder DOID:2978 55 0.010