Homo sapiens

126 known processes

ATR

ataxia telangiectasia and Rad3 related

(Aliases: SCKL1,MEC1,FRP1,SCKL)

ATR biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to dna damage stimulus GO:0006974 379 0.980
ribonucleoside monophosphate catabolic process GO:0009158 158 0.863
purine nucleoside monophosphate catabolic process GO:0009128 158 0.854
dna recombination GO:0006310 77 0.817
Yeast Fly
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.726
dna damage checkpoint GO:0000077 68 0.629
negative regulation of cell cycle process GO:0010948 121 0.600
Fly
double strand break repair GO:0006302 101 0.556
Fly
dna geometric change GO:0032392 32 0.516
g2 m transition of mitotic cell cycle GO:0000086 41 0.440
Fly
purine nucleoside catabolic process GO:0006152 398 0.371
nucleoside monophosphate metabolic process GO:0009123 191 0.367
atp catabolic process GO:0006200 157 0.361
post embryonic development GO:0009791 2 0.359
nucleoside monophosphate catabolic process GO:0009125 159 0.354
organelle fission GO:0048285 149 0.347
Yeast Fly
determination of adult lifespan GO:0008340 2 0.324
mismatch repair GO:0006298 15 0.310
nucleoside phosphate catabolic process GO:1901292 412 0.302
regulation of response to dna damage stimulus GO:2001020 94 0.282
nucleotide catabolic process GO:0009166 408 0.280
ribonucleoside catabolic process GO:0042454 406 0.278
rna processing GO:0006396 255 0.262
purine nucleotide catabolic process GO:0006195 405 0.260
nucleoside triphosphate metabolic process GO:0009141 422 0.252
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.248
regulation of cell cycle phase transition GO:1901987 126 0.238
Fly
ribonucleoside monophosphate metabolic process GO:0009161 187 0.226
regulation of cell cycle GO:0051726 393 0.226
Fly
ncrna processing GO:0034470 83 0.211
multicellular organismal aging GO:0010259 3 0.206
nucleoside triphosphate catabolic process GO:0009143 394 0.194
g2 dna damage checkpoint GO:0031572 26 0.192
Fly
negative regulation of cell cycle phase transition GO:1901988 89 0.189
Fly
dna double strand break processing GO:0000729 10 0.184
Fly
mitotic dna replication checkpoint GO:0033314 2 0.179
Fly
dna duplex unwinding GO:0032508 30 0.176
purine nucleoside triphosphate catabolic process GO:0009146 392 0.168
mitotic cell cycle GO:0000278 326 0.165
Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.163
purine nucleoside triphosphate metabolic process GO:0009144 412 0.157
purine containing compound catabolic process GO:0072523 411 0.146
atp metabolic process GO:0046034 176 0.144
purine ribonucleoside metabolic process GO:0046128 437 0.140
regulation of mitotic cell cycle GO:0007346 189 0.136
Fly
dna repair GO:0006281 198 0.135
Mouse Fly
cell cycle g2 m phase transition GO:0044839 43 0.134
Fly
purine ribonucleotide catabolic process GO:0009154 404 0.129
regulation of mitotic cell cycle phase transition GO:1901990 118 0.127
Fly
negative regulation of mitotic cell cycle GO:0045930 102 0.127
Fly
anatomical structure homeostasis GO:0060249 100 0.126
Yeast Fly
response to caffeine GO:0031000 3 0.122
Fly
nucleoside catabolic process GO:0009164 408 0.116
negative regulation of dna metabolic process GO:0051053 57 0.113
negative regulation of apoptotic process GO:0043066 316 0.112
reproduction GO:0000003 63 0.110
Yeast Fly
nucleotide excision repair GO:0006289 31 0.109
anatomical structure formation involved in morphogenesis GO:0048646 284 0.108
somatic diversification of immunoglobulins involved in immune response GO:0002208 3 0.105
intrinsic apoptotic signaling pathway GO:0097193 127 0.102
ribonucleoside triphosphate catabolic process GO:0009203 391 0.102
glycosyl compound catabolic process GO:1901658 413 0.102
purine ribonucleoside catabolic process GO:0046130 398 0.102
purine nucleoside monophosphate metabolic process GO:0009126 186 0.101
mitotic g2 m transition checkpoint GO:0044818 9 0.090
Fly
apoptotic signaling pathway GO:0097190 268 0.089
dna catabolic process exonucleolytic GO:0000738 17 0.088
Fly
negative regulation of cell death GO:0060548 345 0.084
lipid metabolic process GO:0006629 381 0.079
meiotic chromosome segregation GO:0045132 4 0.079
Fly
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.072
cellular response to organonitrogen compound GO:0071417 124 0.072
cell cycle checkpoint GO:0000075 117 0.071
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.071
Fly
recombinational repair GO:0000725 50 0.070
Fly
aging GO:0007568 66 0.069
response to abiotic stimulus GO:0009628 336 0.067
negative regulation of cell cycle g2 m phase transition GO:1902750 10 0.064
Fly
isotype switching GO:0045190 3 0.062
mitotic cell cycle process GO:1903047 286 0.061
Fly
female gamete generation GO:0007292 2 0.058
regulation of dna metabolic process GO:0051052 153 0.058
cell cycle phase transition GO:0044770 173 0.058
Fly
carbohydrate metabolic process GO:0005975 207 0.057
negative regulation of cell cycle GO:0045786 193 0.055
Fly
protein modification by small protein conjugation GO:0032446 342 0.054
vesicle mediated transport GO:0016192 371 0.051
regulation of cellular response to stress GO:0080135 244 0.051
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 3 0.050
dna integrity checkpoint GO:0031570 71 0.049
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.049
Fly
meiosis i GO:0007127 4 0.048
Yeast Fly
nervous system development GO:0007399 293 0.047
regulation of growth GO:0040008 165 0.045
ribonucleoside triphosphate metabolic process GO:0009199 412 0.045
regulation of double strand break repair GO:2000779 22 0.044
negative regulation of cellular protein metabolic process GO:0032269 353 0.043
mitotic cell cycle phase transition GO:0044772 162 0.042
Fly
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 13 0.042
glycerolipid metabolic process GO:0046486 107 0.041
endomembrane system organization GO:0010256 196 0.040
somatic recombination of immunoglobulin gene segments GO:0016447 4 0.039
organophosphate catabolic process GO:0046434 430 0.039
negative regulation of g2 m transition of mitotic cell cycle GO:0010972 9 0.038
Fly
double strand break repair via homologous recombination GO:0000724 50 0.038
Fly
response to radiation GO:0009314 151 0.037
dna catabolic process GO:0006308 49 0.037
Fly
golgi organization GO:0007030 38 0.037
growth GO:0040007 202 0.035
response to alkaloid GO:0043279 20 0.032
Fly
mrna metabolic process GO:0016071 175 0.031
regulation of cell cycle process GO:0010564 266 0.030
Fly
embryo development ending in birth or egg hatching GO:0009792 34 0.030
regulation of dna replication GO:0006275 68 0.029
lymphocyte activation GO:0046649 133 0.029
ribonucleotide catabolic process GO:0009261 405 0.028
negative regulation of response to dna damage stimulus GO:2001021 33 0.028
dna dependent dna replication GO:0006261 44 0.027
Yeast
mitotic cell cycle checkpoint GO:0007093 68 0.027
Fly
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.027
cellular lipid metabolic process GO:0044255 303 0.026
embryo development GO:0009790 123 0.024
oocyte differentiation GO:0009994 2 0.024
double strand break repair via nonhomologous end joining GO:0006303 10 0.023
positive regulation of phosphorylation GO:0042327 394 0.023
response to nitrogen compound GO:1901698 184 0.023
Fly
cellular response to oxygen containing compound GO:1901701 276 0.022
covalent chromatin modification GO:0016569 254 0.021
Yeast
positive regulation of cellular component organization GO:0051130 376 0.021
microtubule based process GO:0007017 210 0.021
regulation of growth rate GO:0040009 1 0.021
mitotic recombination GO:0006312 8 0.021
Yeast
lymphocyte mediated immunity GO:0002449 48 0.020
organelle assembly GO:0070925 176 0.020
phospholipid metabolic process GO:0006644 99 0.020
reproductive process GO:0022414 106 0.019
ribonucleoprotein complex subunit organization GO:0071826 81 0.019
signal transduction in response to dna damage GO:0042770 57 0.019
regulation of cell growth GO:0001558 135 0.018
generation of precursor metabolites and energy GO:0006091 68 0.018
immune effector process GO:0002252 159 0.018
regulation of cellular ketone metabolic process GO:0010565 50 0.018
response to oxygen containing compound GO:1901700 369 0.018
mitotic dna integrity checkpoint GO:0044774 30 0.018
Fly
telomere organization GO:0032200 33 0.018
Yeast Fly
regulation of helicase activity GO:0051095 8 0.018
central nervous system development GO:0007417 123 0.017
blood vessel development GO:0001568 172 0.017
protein ubiquitination GO:0016567 314 0.017
positive regulation of apoptotic process GO:0043065 246 0.017
signal transduction involved in dna damage checkpoint GO:0072422 15 0.017
mitotic g2 dna damage checkpoint GO:0007095 7 0.017
Fly
meiotic cell cycle process GO:1903046 8 0.017
Yeast Fly
cell type specific apoptotic process GO:0097285 125 0.017
regulation of cellular amino acid metabolic process GO:0006521 6 0.017
signal transduction involved in dna integrity checkpoint GO:0072401 15 0.017
cell growth GO:0016049 160 0.016
positive regulation of protein complex assembly GO:0031334 86 0.016
response to inorganic substance GO:0010035 127 0.016
negative regulation of programmed cell death GO:0043069 321 0.016
neuron differentiation GO:0030182 138 0.016
interstrand cross link repair GO:0036297 3 0.016
regulation of cytoskeleton organization GO:0051493 177 0.016
immune system development GO:0002520 195 0.015
cellular amino acid metabolic process GO:0006520 116 0.015
cell projection organization GO:0030030 252 0.015
dna replication GO:0006260 116 0.015
single organism reproductive process GO:0044702 98 0.015
leukocyte activation GO:0045321 164 0.015
cell part morphogenesis GO:0032990 137 0.015
regulation of cell cycle g2 m phase transition GO:1902749 22 0.014
Fly
vasculature development GO:0001944 181 0.014
cell morphogenesis GO:0000902 296 0.014
Fly
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.014
response to organic cyclic compound GO:0014070 204 0.014
Fly
regulation of cellular component biogenesis GO:0044087 281 0.014
meiotic nuclear division GO:0007126 10 0.014
Yeast Fly
replicative cell aging GO:0001302 3 0.014
telomere maintenance GO:0000723 32 0.013
Yeast Fly
mitotic nuclear division GO:0007067 119 0.013
Fly
ncrna metabolic process GO:0034660 108 0.013
protein dna complex assembly GO:0065004 64 0.013
double strand break repair via single strand annealing GO:0045002 4 0.013
Fly
telomere maintenance via recombination GO:0000722 4 0.013
Yeast
protein polymerization GO:0051258 71 0.013
regulation of g2 m transition of mitotic cell cycle GO:0010389 20 0.013
Fly
cellular amine metabolic process GO:0044106 41 0.013
multicellular organism reproduction GO:0032504 42 0.013
peptidyl serine phosphorylation GO:0018105 101 0.013
regulation of kinase activity GO:0043549 314 0.012
oocyte development GO:0048599 1 0.012
leukocyte mediated immunity GO:0002443 59 0.012
ribonucleoprotein complex biogenesis GO:0022613 116 0.012
regulation of cell division GO:0051302 116 0.012
Fly
defense response GO:0006952 315 0.012
free ubiquitin chain polymerization GO:0010994 2 0.012
intra s dna damage checkpoint GO:0031573 4 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
i kappab kinase nf kappab signaling GO:0007249 166 0.012
dna catabolic process endonucleolytic GO:0000737 37 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
amine metabolic process GO:0009308 44 0.012
regulation of protein complex assembly GO:0043254 147 0.012
neurogenesis GO:0022008 169 0.011
brain development GO:0007420 97 0.011
negative regulation of dna replication GO:0008156 29 0.011
cellular component disassembly GO:0022411 92 0.011
neuron apoptotic process GO:0051402 39 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
regulation of neuron apoptotic process GO:0043523 35 0.011
intracellular protein transport GO:0006886 270 0.011
ribosome biogenesis GO:0042254 48 0.011
regulation of dna repair GO:0006282 47 0.011
protein oligomerization GO:0051259 173 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.010
negative regulation of cellular component organization GO:0051129 235 0.010
cellular macromolecular complex assembly GO:0034622 324 0.010
glycerophospholipid metabolic process GO:0006650 84 0.010
protein targeting GO:0006605 187 0.010
negative regulation of protein metabolic process GO:0051248 391 0.010

ATR disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.116
disease of cellular proliferation DOID:14566 174 0.116
immune system disease DOID:2914 155 0.039
organ system cancer DOID:0050686 164 0.019
disease of metabolism DOID:0014667 295 0.011
inherited metabolic disorder DOID:655 242 0.011
seckel syndrome DOID:0050569 5 0.000