|
|
regulation of endoplasmic reticulum unfolded protein response
|
GO:1900101 |
5 |
0.990
|
|
|
|
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
|
GO:0001844 |
2 |
0.989
|
|
|
|
apoptotic process involved in morphogenesis
|
GO:0060561 |
3 |
0.982
|
|
|
|
mitochondrial membrane organization
|
GO:0007006 |
40 |
0.980
|
|
|
|
regulation of mitochondrial membrane permeability involved in apoptotic process
|
GO:1902108 |
18 |
0.973
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.970
|
Human |
|
|
protein insertion into mitochondrial membrane
|
GO:0051204 |
3 |
0.963
|
|
|
|
positive regulation of apoptotic process involved in mammary gland involution
|
GO:0060058 |
1 |
0.962
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.951
|
Human |
|
|
positive regulation of apoptotic process involved in morphogenesis
|
GO:1902339 |
1 |
0.950
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.941
|
Human |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.933
|
Human Rat |
|
|
regulation of release of cytochrome c from mitochondria
|
GO:0090199 |
29 |
0.933
|
Human Rat |
|
|
positive regulation of protein oligomerization
|
GO:0032461 |
17 |
0.926
|
Human |
|
|
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
|
GO:1901030 |
3 |
0.914
|
|
|
|
regulation of protein oligomerization
|
GO:0032459 |
26 |
0.913
|
Human |
|
|
thymocyte apoptotic process
|
GO:0070242 |
2 |
0.894
|
|
|
|
membrane fusion
|
GO:0061025 |
43 |
0.891
|
Human |
|
|
regulation of mitochondrion organization
|
GO:0010821 |
54 |
0.890
|
Human Rat |
|
|
positive regulation of release of cytochrome c from mitochondria
|
GO:0090200 |
18 |
0.888
|
Human Rat |
|
|
mitochondrial transport
|
GO:0006839 |
60 |
0.888
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.879
|
Human |
|
|
positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902177 |
4 |
0.877
|
Human |
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.872
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.856
|
|
|
|
negative regulation by symbiont of host apoptotic process
|
GO:0033668 |
1 |
0.846
|
Human |
|
|
positive regulation of mitochondrial membrane permeability
|
GO:0035794 |
17 |
0.843
|
|
|
|
modulation by virus of host process
|
GO:0019054 |
2 |
0.843
|
Human |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.838
|
Human Rat |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.824
|
Human Rat |
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.821
|
Human |
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.812
|
Human |
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.796
|
|
|
|
regulation of membrane permeability
|
GO:0090559 |
25 |
0.794
|
|
|
|
modulation by symbiont of host programmed cell death
|
GO:0052040 |
1 |
0.794
|
Human |
|
|
dna catabolic process
|
GO:0006308 |
49 |
0.793
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.791
|
|
|
|
mitochondrial outer membrane permeabilization
|
GO:0097345 |
15 |
0.776
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.772
|
|
|
|
regulation of cellular ph reduction
|
GO:0032847 |
1 |
0.768
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.766
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
35 |
0.760
|
|
|
|
regulation of oxidative stress induced cell death
|
GO:1903201 |
24 |
0.759
|
Human |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.756
|
|
|
|
modulation by virus of host morphology or physiology
|
GO:0019048 |
10 |
0.752
|
Human |
|
|
positive regulation of mitochondrion organization
|
GO:0010822 |
30 |
0.751
|
Human Rat |
|
|
membrane organization
|
GO:0061024 |
292 |
0.749
|
|
|
|
modulation by organism of apoptotic process in other organism involved in symbiotic interaction
|
GO:0052433 |
1 |
0.749
|
Human |
|
|
negative regulation of execution phase of apoptosis
|
GO:1900118 |
6 |
0.733
|
Human |
|
|
regulation of mitochondrial membrane permeability
|
GO:0046902 |
25 |
0.726
|
|
|
|
modulation of apoptotic process in other organism
|
GO:0044532 |
1 |
0.706
|
Human |
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.701
|
Human |
|
|
regulation of apoptotic dna fragmentation
|
GO:1902510 |
3 |
0.688
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.686
|
|
|
|
single organism membrane fusion
|
GO:0044801 |
37 |
0.685
|
Human |
|
|
regulation of apoptotic process involved in morphogenesis
|
GO:1902337 |
1 |
0.684
|
|
|
|
establishment or maintenance of transmembrane electrochemical gradient
|
GO:0010248 |
2 |
0.682
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.659
|
Human |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.658
|
|
|
|
positive regulation of response to oxidative stress
|
GO:1902884 |
7 |
0.654
|
Human |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.650
|
|
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.645
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.642
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.638
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.636
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.629
|
|
|
|
protein localization to mitochondrion
|
GO:0070585 |
25 |
0.627
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.624
|
|
|
|
positive regulation of oxidative stress induced cell death
|
GO:1903209 |
5 |
0.618
|
Human |
|
|
mitochondrial outer membrane permeabilization involved in programmed cell death
|
GO:1902686 |
16 |
0.606
|
|
|
|
mitochondrial fission
|
GO:0000266 |
14 |
0.599
|
Human |
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.596
|
|
|
|
modulation by virus of host apoptotic process
|
GO:0039526 |
1 |
0.587
|
Human |
|
|
fear response
|
GO:0042596 |
0 |
0.583
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.583
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.572
|
|
|
|
positive regulation of mitochondrial membrane permeability involved in apoptotic process
|
GO:1902110 |
16 |
0.568
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.566
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
16 |
0.566
|
Human |
|
|
t cell homeostasis
|
GO:0043029 |
3 |
0.565
|
|
|
|
negative regulation of establishment of protein localization to plasma membrane
|
GO:0090005 |
9 |
0.564
|
Human |
|
|
cytokinesis
|
GO:0000910 |
96 |
0.549
|
Human |
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.545
|
Human |
|
|
modulation of programmed cell death in other organism involved in symbiotic interaction
|
GO:0052248 |
1 |
0.543
|
Human |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.536
|
|
|
|
transformed cell apoptotic process
|
GO:0006927 |
3 |
0.530
|
Human |
|
|
defense response to virus
|
GO:0051607 |
71 |
0.517
|
|
|
|
behavioral defense response
|
GO:0002209 |
0 |
0.517
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.512
|
Human |
|
|
modulation by symbiont of host cellular process
|
GO:0044068 |
3 |
0.506
|
Human |
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.504
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.504
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.497
|
|
|
|
organelle fusion
|
GO:0048284 |
36 |
0.496
|
Human |
|
|
regulation of oxidative stress induced neuron death
|
GO:1903203 |
9 |
0.491
|
Human |
|
|
t cell apoptotic process
|
GO:0070231 |
12 |
0.490
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.480
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.479
|
Human |
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.476
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.475
|
|
|
|
dna catabolic process endonucleolytic
|
GO:0000737 |
37 |
0.468
|
Human |
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.466
|
Human |
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.462
|
Human |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.458
|
Human Rat |
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.453
|
Human |
|
|
positive regulation of protein homooligomerization
|
GO:0032464 |
7 |
0.447
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.446
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.446
|
Human |
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.443
|
|
|
|
response to salt stress
|
GO:0009651 |
3 |
0.441
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.433
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.431
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.426
|
|
|
|
phototransduction
|
GO:0007602 |
3 |
0.416
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.411
|
Human |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.407
|
Human |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.404
|
Human |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.401
|
|
|
|
apoptotic nuclear changes
|
GO:0030262 |
13 |
0.399
|
Human |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.399
|
Human |
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.398
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.397
|
|
|
|
regulation of execution phase of apoptosis
|
GO:1900117 |
11 |
0.395
|
Human |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.391
|
Human |
|
|
viral process
|
GO:0016032 |
146 |
0.390
|
Human |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.385
|
Human |
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.385
|
Human |
|
|
negative regulation of endoplasmic reticulum calcium ion concentration
|
GO:0032471 |
6 |
0.384
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.382
|
|
|
|
patterning of blood vessels
|
GO:0001569 |
2 |
0.380
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.380
|
|
|
|
modification by symbiont of host morphology or physiology
|
GO:0044003 |
12 |
0.379
|
Human |
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.377
|
Human |
|
|
positive regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway
|
GO:1903378 |
2 |
0.373
|
Human |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.370
|
|
|
|
regulation of protein heterodimerization activity
|
GO:0043497 |
5 |
0.367
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.363
|
Human |
|
|
interaction with host
|
GO:0051701 |
42 |
0.354
|
Human |
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.349
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.347
|
Human |
|
|
positive regulation of fibroblast apoptotic process
|
GO:2000271 |
6 |
0.345
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.344
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.341
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.339
|
|
|
|
modulation by symbiont of host apoptotic process
|
GO:0052150 |
1 |
0.337
|
Human |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.337
|
|
|
|
neuron death in response to oxidative stress
|
GO:0036475 |
9 |
0.336
|
Human |
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.336
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.333
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.332
|
|
|
|
positive regulation of cellular response to oxidative stress
|
GO:1900409 |
7 |
0.327
|
Human |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.327
|
|
|
|
inner mitochondrial membrane organization
|
GO:0007007 |
8 |
0.324
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.322
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.321
|
|
|
|
cellular component disassembly involved in execution phase of apoptosis
|
GO:0006921 |
13 |
0.319
|
Human |
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.316
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.311
|
Human |
|
|
response to radiation
|
GO:0009314 |
151 |
0.310
|
|
|
|
endoplasmic reticulum unfolded protein response
|
GO:0030968 |
16 |
0.306
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.300
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.299
|
Human |
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.294
|
Human |
|
|
leukocyte apoptotic process
|
GO:0071887 |
31 |
0.292
|
Human |
|
|
response to virus
|
GO:0009615 |
126 |
0.290
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.286
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.283
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.281
|
Human |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.279
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.279
|
Rat |
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.277
|
Human |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.275
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.275
|
Human |
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.274
|
|
|
|
cellular response to unfolded protein
|
GO:0034620 |
16 |
0.271
|
|
|
|
hypothalamus development
|
GO:0021854 |
1 |
0.269
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.268
|
Human |
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.268
|
|
|
|
release of matrix enzymes from mitochondria
|
GO:0032976 |
1 |
0.265
|
Human |
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.262
|
|
|
|
positive regulation of calcium ion transport into cytosol
|
GO:0010524 |
20 |
0.259
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
20 |
0.259
|
Human |
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
33 |
0.243
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.242
|
Human |
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.239
|
Human |
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.238
|
|
|
|
neuron intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0036480 |
7 |
0.238
|
Human |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.236
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.235
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.233
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001269 |
1 |
0.231
|
|
|
|
apoptotic process involved in mammary gland involution
|
GO:0060057 |
1 |
0.231
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.229
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.228
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.226
|
Human |
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.225
|
Human |
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.224
|
|
|
|
developmental pigmentation
|
GO:0048066 |
12 |
0.223
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.223
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.221
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.219
|
Human |
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.219
|
|
|
|
execution phase of apoptosis
|
GO:0097194 |
32 |
0.218
|
Human |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.218
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.216
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.214
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.213
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.213
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.211
|
|
|
|
growth
|
GO:0040007 |
202 |
0.210
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.209
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.209
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.203
|
|
|
|
positive regulation of oxidative stress induced neuron death
|
GO:1903223 |
2 |
0.201
|
Human |
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.200
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.199
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.198
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
8 |
0.197
|
Human |
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
21 |
0.196
|
Human |
|
|
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
|
GO:0070059 |
12 |
0.195
|
Human |
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.195
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.192
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.189
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.189
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.189
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.188
|
Human |
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.188
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.187
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.186
|
Human |
|
|
regulation of response to oxidative stress
|
GO:1902882 |
26 |
0.185
|
Human |
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.185
|
Human |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.183
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.183
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.182
|
|
|
|
pallium development
|
GO:0021543 |
10 |
0.180
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.176
|
|
|
|
establishment of protein localization to mitochondrion
|
GO:0072655 |
22 |
0.176
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
18 |
0.175
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.175
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.170
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.170
|
|
|
|
positive regulation of b cell apoptotic process
|
GO:0002904 |
1 |
0.168
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.167
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.166
|
Human |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.164
|
Human |
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.164
|
Human |
|
|
embryonic digit morphogenesis
|
GO:0042733 |
6 |
0.163
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.162
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.160
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.160
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.160
|
|
|
|
positive regulation of calcium ion transport
|
GO:0051928 |
51 |
0.159
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.157
|
|
|
|
regulation of sequestering of calcium ion
|
GO:0051282 |
41 |
0.156
|
|
|
|
regulation of mitochondrial membrane potential
|
GO:0051881 |
23 |
0.153
|
|
|
|
modulation of programmed cell death in other organism
|
GO:0044531 |
1 |
0.152
|
Human |
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
40 |
0.152
|
Human |
|
|
response to uv
|
GO:0009411 |
73 |
0.151
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.150
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c
|
GO:0008635 |
2 |
0.148
|
Human |
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.147
|
Human |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.146
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
25 |
0.145
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.145
|
Human |
|
|
regulation of growth
|
GO:0040008 |
165 |
0.145
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.144
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.142
|
|
|
|
regulation of developmental pigmentation
|
GO:0048070 |
2 |
0.141
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.141
|
Human |
|
|
er nucleus signaling pathway
|
GO:0006984 |
23 |
0.140
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.138
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.137
|
Human |
|
|
cerebral cortex development
|
GO:0021987 |
10 |
0.137
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.136
|
|
|
|
mammary gland involution
|
GO:0060056 |
1 |
0.135
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.135
|
Human |
|
|
regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902175 |
16 |
0.134
|
Human |
|
|
positive regulation of endoplasmic reticulum unfolded protein response
|
GO:1900103 |
4 |
0.134
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.134
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.134
|
Human |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.134
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.133
|
Human |
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.133
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001267 |
2 |
0.132
|
|
|
|
negative regulation of peptidyl serine phosphorylation
|
GO:0033137 |
8 |
0.132
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.130
|
|
|
|
regulation of intracellular ph
|
GO:0051453 |
16 |
0.128
|
|
|
|
vacuole organization
|
GO:0007033 |
44 |
0.127
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.127
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.126
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.126
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.126
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.125
|
Human |
|
|
lymphocyte apoptotic process
|
GO:0070227 |
20 |
0.124
|
Human |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.123
|
|
|
|
retinal cell apoptotic process
|
GO:1990009 |
1 |
0.123
|
Human |
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.122
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.122
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.120
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.117
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.116
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.116
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.114
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.113
|
Human |
|
|
b cell homeostasis
|
GO:0001782 |
1 |
0.113
|
|
|
|
blood vessel remodeling
|
GO:0001974 |
2 |
0.112
|
|
|
|
fibroblast apoptotic process
|
GO:0044346 |
8 |
0.111
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.110
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.110
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.109
|
|
|
|
mitochondrion morphogenesis
|
GO:0070584 |
8 |
0.109
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.106
|
|
|
|
positive regulation of release of sequestered calcium ion into cytosol
|
GO:0051281 |
16 |
0.106
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
3 |
0.106
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.105
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.104
|
Human |
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.104
|
|
|
|
positive regulation of killing of cells of other organism
|
GO:0051712 |
4 |
0.103
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.102
|
Human |
|
|
regulation of release of sequestered calcium ion into cytosol
|
GO:0051279 |
27 |
0.101
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.100
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.100
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
24 |
0.100
|
|
|
|
female genitalia development
|
GO:0030540 |
2 |
0.099
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.099
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.099
|
|
|
|
response to alkaloid
|
GO:0043279 |
20 |
0.098
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.098
|
|
|
|
negative regulation of protein binding
|
GO:0032091 |
35 |
0.098
|
Human |
|
|
regulation of protein homooligomerization
|
GO:0032462 |
11 |
0.097
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.097
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.097
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.096
|
|
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
26 |
0.096
|
Human |
|
|
cell division
|
GO:0051301 |
168 |
0.096
|
Human |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.095
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.095
|
Human |
|
|
thymus development
|
GO:0048538 |
3 |
0.094
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.093
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.093
|
|
|
|
protein insertion into membrane
|
GO:0051205 |
9 |
0.093
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.093
|
|
|
|
response to unfolded protein
|
GO:0006986 |
24 |
0.093
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.092
|
Rat |
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.092
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.091
|
|
|
|
regulation of establishment of protein localization to plasma membrane
|
GO:0090003 |
30 |
0.091
|
Human |
|
|
response to cocaine
|
GO:0042220 |
1 |
0.090
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.090
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.090
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.090
|
|
|
|
positive regulation of dna catabolic process
|
GO:1903626 |
2 |
0.089
|
Human |
|
|
epithelium development
|
GO:0060429 |
227 |
0.089
|
|
|
|
apoptotic dna fragmentation
|
GO:0006309 |
6 |
0.089
|
Human |
|
|
semaphorin plexin signaling pathway
|
GO:0071526 |
4 |
0.089
|
|
|
|
mitochondrial fragmentation involved in apoptotic process
|
GO:0043653 |
7 |
0.088
|
Human |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.088
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.087
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.087
|
Human |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.086
|
Human |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.086
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.086
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.085
|
|
|
|
response to gamma radiation
|
GO:0010332 |
14 |
0.085
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.085
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.085
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.085
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.084
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.083
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.083
|
Human |
|
|
regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
|
GO:1901028 |
9 |
0.083
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
22 |
0.081
|
Human |
|
|
negative regulation of anoikis
|
GO:2000811 |
15 |
0.081
|
Human |
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.081
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.081
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.081
|
Human |
|
|
response to transition metal nanoparticle
|
GO:1990267 |
29 |
0.081
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.080
|
Human |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.080
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.079
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
2 |
0.079
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.078
|
|
|
|
sphingolipid metabolic process
|
GO:0006665 |
38 |
0.078
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.078
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.078
|
Rat |
|
|
cellular monovalent inorganic cation homeostasis
|
GO:0030004 |
26 |
0.077
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
43 |
0.077
|
Human |
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.077
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.076
|
Human |
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.076
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.076
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.076
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.076
|
|
|
|
tissue homeostasis
|
GO:0001894 |
63 |
0.075
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001241 |
4 |
0.075
|
|
|
|
cellular response to light stimulus
|
GO:0071482 |
34 |
0.075
|
|
|
|
liposaccharide metabolic process
|
GO:1903509 |
27 |
0.074
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.074
|
|
|
|
tissue remodeling
|
GO:0048771 |
16 |
0.074
|
|
|
|
anoikis
|
GO:0043276 |
22 |
0.073
|
Human |
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.072
|
|
|
|
monovalent inorganic cation homeostasis
|
GO:0055067 |
37 |
0.072
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.072
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.072
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.072
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.071
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.071
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.071
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.070
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.068
|
Human |
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.068
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.068
|
Rat |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.068
|
Human |
|
|
odontogenesis
|
GO:0042476 |
25 |
0.068
|
|
|
|
regulation of mitochondrial fusion
|
GO:0010635 |
5 |
0.067
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.067
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
1 |
0.066
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.066
|
|
|
|
glycolipid metabolic process
|
GO:0006664 |
27 |
0.066
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.066
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.066
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.065
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.065
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
22 |
0.065
|
Human |
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.064
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.064
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.064
|
Human |
|
|
angiogenesis
|
GO:0001525 |
147 |
0.064
|
|
|
|
negative regulation of fibroblast proliferation
|
GO:0048147 |
12 |
0.064
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.063
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.063
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.063
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.063
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.063
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.062
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.062
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.062
|
Rat |
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.061
|
|
|
|
negative regulation of protein localization to plasma membrane
|
GO:1903077 |
13 |
0.060
|
Human |
|
|
development of primary male sexual characteristics
|
GO:0046546 |
23 |
0.060
|
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.060
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.059
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.059
|
Human |
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.058
|
|
|
|
mitochondrial fusion
|
GO:0008053 |
13 |
0.058
|
Human |
|
|
spermatid development
|
GO:0007286 |
4 |
0.058
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.057
|
|
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
25 |
0.057
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.057
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.057
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.057
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.056
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.056
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.056
|
|
|
|
male sex differentiation
|
GO:0046661 |
25 |
0.056
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.056
|
|
|
|
negative regulation of sequestering of calcium ion
|
GO:0051283 |
41 |
0.056
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.055
|
|
|
|
female gonad development
|
GO:0008585 |
10 |
0.055
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.055
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
15 |
0.055
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.055
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
12 |
0.055
|
|
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.054
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.054
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.054
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.054
|
Human |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.054
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.053
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.053
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.053
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.053
|
|
|
|
negative regulation of response to dna damage stimulus
|
GO:2001021 |
33 |
0.053
|
Human |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.052
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.052
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.052
|
Human |
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.052
|
|
|
|
regulation of ph
|
GO:0006885 |
20 |
0.052
|
|
|
|
regulation of b cell apoptotic process
|
GO:0002902 |
5 |
0.051
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.051
|
|
|
|
apoptotic process in bone marrow
|
GO:0071839 |
1 |
0.051
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.051
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.051
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.051
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.051
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.051
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.050
|
|
|
|
modification of morphology or physiology of other organism involved in symbiotic interaction
|
GO:0051817 |
38 |
0.050
|
Human |
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.050
|
|
