Homo sapiens

91 known processes

BBS7

Bardet-Biedl syndrome 7

(Aliases: FLJ10715,BBS2L1)

BBS7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cilium assembly GO:0042384 63 0.979
photoreceptor cell maintenance GO:0045494 13 0.791
cilium morphogenesis GO:0060271 75 0.740
sensory perception of smell GO:0007608 2 0.486
cilium organization GO:0044782 68 0.422
cell projection assembly GO:0030031 126 0.313
cellular response to external stimulus GO:0071496 111 0.254
cellular component assembly involved in morphogenesis GO:0010927 73 0.214
organelle assembly GO:0070925 176 0.184
purine nucleoside triphosphate catabolic process GO:0009146 392 0.161
epithelium development GO:0060429 227 0.157
intracellular protein transport GO:0006886 270 0.150
cellular component morphogenesis GO:0032989 314 0.143
cell projection organization GO:0030030 252 0.135
protein localization to organelle GO:0033365 280 0.129
fat cell differentiation GO:0045444 32 0.120
Mouse
nucleoside triphosphate catabolic process GO:0009143 394 0.119
nonmotile primary cilium assembly GO:0035058 4 0.117
nucleoside triphosphate metabolic process GO:0009141 422 0.102
protein localization to membrane GO:0072657 160 0.099
axis elongation GO:0003401 4 0.099
glycosyl compound catabolic process GO:1901658 413 0.097
purine nucleoside catabolic process GO:0006152 398 0.095
single organism cellular localization GO:1902580 332 0.095
cellular macromolecular complex assembly GO:0034622 324 0.093
photoreceptor cell differentiation GO:0046530 2 0.088
ribonucleoside triphosphate metabolic process GO:0009199 412 0.088
cellular protein complex assembly GO:0043623 188 0.082
cell morphogenesis GO:0000902 296 0.081
nucleoside monophosphate metabolic process GO:0009123 191 0.079
purine nucleotide catabolic process GO:0006195 405 0.078
vesicle mediated transport GO:0016192 371 0.077
anatomical structure formation involved in morphogenesis GO:0048646 284 0.071
neural tube formation GO:0001841 3 0.070
purine nucleoside monophosphate metabolic process GO:0009126 186 0.070
cell projection morphogenesis GO:0048858 129 0.070
cytoplasmic transport GO:0016482 379 0.070
cellular response to endogenous stimulus GO:0071495 336 0.069
organophosphate catabolic process GO:0046434 430 0.066
post golgi vesicle mediated transport GO:0006892 36 0.065
purine containing compound catabolic process GO:0072523 411 0.064
regulation of nucleotide catabolic process GO:0030811 205 0.061
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation GO:0044338 2 0.060
positive regulation of cellular component organization GO:0051130 376 0.058
negative regulation of blood pressure GO:0045776 3 0.058
maintenance of location GO:0051235 112 0.058
nucleotide catabolic process GO:0009166 408 0.057
negative regulation of cell death GO:0060548 345 0.057
segmentation GO:0035282 4 0.056
protein localization to plasma membrane GO:0072659 93 0.056
atp catabolic process GO:0006200 157 0.055
cofactor metabolic process GO:0051186 87 0.054
post embryonic development GO:0009791 2 0.054
negative regulation of programmed cell death GO:0043069 321 0.052
nervous system development GO:0007399 293 0.051
Mouse
nucleoside catabolic process GO:0009164 408 0.051
establishment of protein localization to plasma membrane GO:0090002 68 0.051
eye development GO:0001654 42 0.050
Mouse
positive regulation of catabolic process GO:0009896 310 0.049
ribonucleoside monophosphate metabolic process GO:0009161 187 0.048
tube development GO:0035295 125 0.048
regulation of locomotion GO:0040012 329 0.047
positive regulation of nucleotide catabolic process GO:0030813 185 0.047
circulatory system development GO:0072359 262 0.047
Mouse
nucleoside phosphate catabolic process GO:1901292 412 0.047
chemical homeostasis GO:0048878 306 0.046
ribonucleoside triphosphate catabolic process GO:0009203 391 0.045
cellular response to cytokine stimulus GO:0071345 181 0.045
endomembrane system organization GO:0010256 196 0.045
ribonucleoside catabolic process GO:0042454 406 0.044
membrane organization GO:0061024 292 0.043
coenzyme metabolic process GO:0006732 65 0.043
single organism membrane organization GO:0044802 268 0.042
negative regulation of ectodermal cell fate specification GO:0042666 1 0.042
neuromuscular junction development GO:0007528 3 0.041
positive regulation of hydrolase activity GO:0051345 331 0.041
atp metabolic process GO:0046034 176 0.041
ribonucleotide catabolic process GO:0009261 405 0.041
cell part morphogenesis GO:0032990 137 0.040
positive regulation of nucleoside metabolic process GO:0045979 186 0.040
pattern specification involved in kidney development GO:0061004 1 0.040
canonical wnt signaling pathway involved in osteoblast differentiation GO:0044339 2 0.040
regulation of purine nucleotide catabolic process GO:0033121 205 0.039
purine ribonucleoside catabolic process GO:0046130 398 0.038
eye morphogenesis GO:0048592 16 0.038
regulation of nucleoside metabolic process GO:0009118 209 0.038
regulation of sodium dependent phosphate transport GO:2000118 2 0.038
negative regulation of protein metabolic process GO:0051248 391 0.037
paramesonephric duct development GO:0061205 2 0.037
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.037
mesonephric tubule formation GO:0072172 1 0.036
neural tube closure GO:0001843 3 0.036
gtp metabolic process GO:0046039 239 0.036
golgi vesicle transport GO:0048193 80 0.036
purine nucleoside monophosphate catabolic process GO:0009128 158 0.036
establishment of protein localization to membrane GO:0090150 121 0.035
ribonucleoside monophosphate catabolic process GO:0009158 158 0.035
mitotic cell cycle GO:0000278 326 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.035
negative regulation of apoptotic process GO:0043066 316 0.035
embryonic epithelial tube formation GO:0001838 4 0.034
nephron tubule formation GO:0072079 1 0.034
purine ribonucleotide catabolic process GO:0009154 404 0.034
nucleoside monophosphate catabolic process GO:0009125 159 0.034
organ morphogenesis GO:0009887 147 0.033
regulation of cellular component biogenesis GO:0044087 281 0.032
neuron differentiation GO:0030182 138 0.031
oxidation reduction process GO:0055114 396 0.031
mitotic cell cycle process GO:1903047 286 0.031
epithelial tube morphogenesis GO:0060562 38 0.031
lipid metabolic process GO:0006629 381 0.030
blastoderm segmentation GO:0007350 2 0.030
guanosine containing compound catabolic process GO:1901069 239 0.030
negative regulation of catalytic activity GO:0043086 335 0.030
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.030
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.030
purine nucleoside triphosphate metabolic process GO:0009144 412 0.029
guanosine containing compound metabolic process GO:1901068 244 0.029
response to lipid GO:0033993 206 0.029
locomotory behavior GO:0007626 1 0.029
multicellular organismal homeostasis GO:0048871 67 0.029
somatic stem cell maintenance GO:0035019 4 0.029
embryonic morphogenesis GO:0048598 85 0.028
eye photoreceptor cell differentiation GO:0001754 2 0.028
sensory perception of chemical stimulus GO:0007606 38 0.027
head development GO:0060322 108 0.027
Mouse
anatomical structure homeostasis GO:0060249 100 0.027
regulation of protein complex assembly GO:0043254 147 0.027
positive regulation of cellular catabolic process GO:0031331 284 0.027
ion homeostasis GO:0050801 230 0.026
tube morphogenesis GO:0035239 95 0.026
positive regulation of developmental process GO:0051094 314 0.026
renal system development GO:0072001 63 0.025
sensory organ morphogenesis GO:0090596 21 0.025
anterior posterior axis specification embryo GO:0008595 2 0.025
wnt signaling pathway GO:0016055 156 0.025
plasma membrane organization GO:0007009 115 0.025
regulation of purine nucleotide metabolic process GO:1900542 264 0.025
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.025
gtp catabolic process GO:0006184 237 0.025
cellular response to extracellular stimulus GO:0031668 72 0.025
lung alveolus development GO:0048286 4 0.024
sensory organ development GO:0007423 52 0.024
Mouse
protein processing GO:0016485 226 0.024
covalent chromatin modification GO:0016569 254 0.024
convergent extension GO:0060026 1 0.024
response to cytokine GO:0034097 232 0.024
vasodilation GO:0042311 4 0.024
regulation of kinase activity GO:0043549 314 0.023
regulation of cellular response to stress GO:0080135 244 0.023
histone modification GO:0016570 251 0.022
positive regulation of nucleotide metabolic process GO:0045981 230 0.022
regulation of nucleotide metabolic process GO:0006140 269 0.022
negative regulation of hydrolase activity GO:0051346 182 0.022
central nervous system development GO:0007417 123 0.022
Mouse
determination of left right symmetry GO:0007368 11 0.022
regulation of atpase activity GO:0043462 25 0.021
protein ubiquitination GO:0016567 314 0.021
regulation of cilium movement GO:0003352 3 0.021
regulation of fat cell differentiation GO:0045598 23 0.021
cell morphogenesis involved in differentiation GO:0000904 144 0.021
blood circulation GO:0008015 113 0.020
positive regulation of cellular amine metabolic process GO:0033240 7 0.020
centrosome organization GO:0051297 58 0.020
cellular amino acid metabolic process GO:0006520 116 0.020
regulation of protein localization GO:0032880 296 0.020
mating GO:0007618 1 0.020
regulation of cell differentiation GO:0045595 393 0.020
protein modification by small protein conjugation GO:0032446 342 0.020
microtubule cytoskeleton organization GO:0000226 176 0.020
chromatin organization GO:0006325 351 0.020
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.020
regulation of metanephros size GO:0035566 1 0.020
regulation of cell motility GO:2000145 299 0.020
system process GO:0003008 349 0.020
multicellular organismal aging GO:0010259 3 0.019
cardiovascular system development GO:0072358 262 0.019
Mouse
maintenance of location in cell GO:0051651 62 0.019
anterior posterior axis specification GO:0009948 2 0.019
chaperone mediated protein complex assembly GO:0051131 9 0.019
mesonephric duct development GO:0072177 3 0.019
primary neural tube formation GO:0014020 3 0.019
response to organic cyclic compound GO:0014070 204 0.019
retina homeostasis GO:0001895 42 0.019
protein maturation GO:0051604 233 0.019
negative regulation of cell proliferation GO:0008285 228 0.019
oxidoreduction coenzyme metabolic process GO:0006733 19 0.019
amine metabolic process GO:0009308 44 0.019
protein polyubiquitination GO:0000209 110 0.019
regulation of establishment of protein localization GO:0070201 242 0.018
regulation of epithelial cell proliferation GO:0050678 113 0.018
cellular response to oxygen containing compound GO:1901701 276 0.018
positive regulation of atpase activity GO:0032781 19 0.018
regulation of cellular amine metabolic process GO:0033238 11 0.018
tissue morphogenesis GO:0048729 96 0.018
response to camp GO:0051591 25 0.018
response to oxidative stress GO:0006979 121 0.018
mesodermal cell fate specification GO:0007501 2 0.018
negative regulation of sodium dependent phosphate transport GO:2000119 1 0.018
maintenance of protein location in cell GO:0032507 56 0.018
regulation of response to external stimulus GO:0032101 222 0.017
metal ion homeostasis GO:0055065 169 0.017
spermatid differentiation GO:0048515 4 0.017
positive regulation of protein kinase activity GO:0045860 190 0.017
cell adhesion GO:0007155 325 0.017
spemann organizer formation GO:0060061 1 0.017
retina development in camera type eye GO:0060041 15 0.017
neural tube patterning GO:0021532 2 0.017
epithelial cell proliferation GO:0050673 128 0.017
response to axon injury GO:0048678 1 0.017
camera type eye photoreceptor cell differentiation GO:0060219 1 0.017
regulation of glomerulus development GO:0090192 3 0.017
epithelial cell differentiation GO:0030855 141 0.016
tripartite regional subdivision GO:0007351 2 0.016
response to inorganic substance GO:0010035 127 0.016
regulation of ion transport GO:0043269 189 0.016
regulation of cell cycle phase transition GO:1901987 126 0.016
cellular response to dna damage stimulus GO:0006974 379 0.016
secretion by cell GO:0032940 226 0.016
microtubule based process GO:0007017 210 0.016
transmembrane transport GO:0055085 399 0.016
bud outgrowth involved in lung branching GO:0060447 1 0.016
regulation of protein transport GO:0051223 213 0.016
regulation of cell migration GO:0030334 289 0.016
embryonic organ morphogenesis GO:0048562 24 0.016
regeneration GO:0031099 4 0.016
biological adhesion GO:0022610 331 0.016
response to hormone GO:0009725 175 0.016
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.016
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.016
tube closure GO:0060606 3 0.016
associative learning GO:0008306 1 0.016
eye pigmentation GO:0048069 1 0.015
regulation of intracellular transport GO:0032386 195 0.015
morphogenesis of embryonic epithelium GO:0016331 4 0.015
cation homeostasis GO:0055080 189 0.015
ubiquitin dependent protein catabolic process GO:0006511 206 0.015
positive regulation of transferase activity GO:0051347 227 0.015
response to abiotic stimulus GO:0009628 336 0.015
regulation of jnk cascade GO:0046328 73 0.015
neuron development GO:0048666 113 0.015
positive regulation of cell proliferation GO:0008284 301 0.015
protein localization to nucleus GO:0034504 136 0.015
reactive oxygen species metabolic process GO:0072593 75 0.015
regulation of mitotic cell cycle phase transition GO:1901990 118 0.015
cellular response to organonitrogen compound GO:0071417 124 0.015
protein targeting GO:0006605 187 0.015
negative regulation of cellular protein metabolic process GO:0032269 353 0.015
response to starvation GO:0042594 59 0.015
regulation of cell cycle process GO:0010564 266 0.015
chromatin modification GO:0016568 298 0.015
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.015
cellular response to starvation GO:0009267 58 0.014
actin filament based process GO:0030029 224 0.014
cell type specific apoptotic process GO:0097285 125 0.014
negative regulation of endopeptidase activity GO:0010951 84 0.014
pattern specification process GO:0007389 43 0.014
response to metal ion GO:0010038 84 0.014
maintenance of protein location GO:0045185 57 0.014
regulation of atp metabolic process GO:1903578 29 0.014
response to extracellular stimulus GO:0009991 85 0.014
response to oxygen containing compound GO:1901700 369 0.014
positive regulation of cellular component movement GO:0051272 181 0.014
positive regulation of synaptic transmission GO:0050806 4 0.014
protein oligomerization GO:0051259 173 0.014
nadh metabolic process GO:0006734 1 0.014
regulation of cell morphogenesis GO:0022604 153 0.014
negative regulation of wnt signaling pathway GO:0030178 69 0.014
nitrogen compound transport GO:0071705 191 0.014
regulation of phosphate transport GO:0010966 3 0.014
reactive oxygen species biosynthetic process GO:1903409 4 0.013
organ formation GO:0048645 3 0.013
inner ear morphogenesis GO:0042472 4 0.013
regulation of cell adhesion GO:0030155 166 0.013
determination of adult lifespan GO:0008340 2 0.013
golgi to plasma membrane protein transport GO:0043001 19 0.013
regulation of intracellular protein transport GO:0033157 123 0.013
hindbrain development GO:0030902 3 0.013
negative regulation of multicellular organismal process GO:0051241 317 0.013
urogenital system development GO:0001655 65 0.013
carbohydrate metabolic process GO:0005975 207 0.013
positive regulation of cellular component biogenesis GO:0044089 158 0.013
compound eye development GO:0048749 1 0.013
sensory perception GO:0007600 103 0.013
monosaccharide metabolic process GO:0005996 74 0.013
cell cycle phase transition GO:0044770 173 0.013
positive regulation of kinase activity GO:0033674 204 0.013
protein import GO:0017038 130 0.013
protein targeting to nucleus GO:0044744 104 0.013
digestive tract morphogenesis GO:0048546 56 0.012
response to acid chemical GO:0001101 66 0.012
response to nutrient levels GO:0031667 81 0.012
regulation of reactive oxygen species metabolic process GO:2000377 41 0.012
response to wounding GO:0009611 168 0.012
toxin transport GO:1901998 4 0.012
regulation of protein processing GO:0070613 150 0.012
negative regulation of systemic arterial blood pressure GO:0003085 1 0.012
calcium ion homeostasis GO:0055074 122 0.012
regulation of proteolysis GO:0030162 293 0.012
neurological system process GO:0050877 163 0.012
regulation of cellular component movement GO:0051270 334 0.012
cellular protein catabolic process GO:0044257 261 0.012
distal tubule development GO:0072017 4 0.012
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.012
actin filament based movement GO:0030048 17 0.012
response to zinc ion GO:0010043 12 0.012
camera type eye development GO:0043010 25 0.012
negative regulation of transport GO:0051051 176 0.012
negative regulation of cell differentiation GO:0045596 171 0.012
signal transduction by phosphorylation GO:0023014 297 0.012
reactive nitrogen species metabolic process GO:2001057 3 0.012
morphogenesis of an epithelium GO:0002009 60 0.012
collateral sprouting GO:0048668 2 0.012
ion transmembrane transport GO:0034220 338 0.012
cell growth GO:0016049 160 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.012
regulation of protein maturation GO:1903317 150 0.012
cytokinesis GO:0000910 96 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.012
divalent inorganic cation homeostasis GO:0072507 136 0.012
negative regulation of proteolysis GO:0045861 132 0.012
regulation of cysteine type endopeptidase activity GO:2000116 127 0.012
regulation of secretion by cell GO:1903530 177 0.011
positive regulation of stress activated mapk cascade GO:0032874 60 0.011
cellular amine metabolic process GO:0044106 41 0.011
rho protein signal transduction GO:0007266 26 0.011
protein import into nucleus GO:0006606 104 0.011
oocyte development GO:0048599 1 0.011
cation transmembrane transport GO:0098655 238 0.011
female gamete generation GO:0007292 2 0.011
response to steroid hormone GO:0048545 80 0.011
regulation of vesicle mediated transport GO:0060627 130 0.011
negative regulation of camp mediated signaling GO:0043951 4 0.011
cell substrate adhesion GO:0031589 132 0.011
negative regulation of cell fate commitment GO:0010454 3 0.011
regulation of cytoplasmic transport GO:1903649 149 0.011
purine ribonucleoside metabolic process GO:0046128 437 0.011
negative regulation of cell cycle GO:0045786 193 0.011
secretion GO:0046903 254 0.011
autocrine signaling GO:0035425 2 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
golgi to plasma membrane transport GO:0006893 21 0.011
smoothened signaling pathway GO:0007224 14 0.011
Mouse
inorganic cation transmembrane transport GO:0098662 194 0.011
regulation of ectoderm development GO:2000383 1 0.011
vasculature development GO:0001944 181 0.011
regulation of cell development GO:0060284 161 0.011
positive regulation of epithelial cell proliferation involved in wound healing GO:0060054 3 0.011
mitochondrion organization GO:0007005 156 0.011
cell cell signaling GO:0007267 155 0.011
apoptotic signaling pathway GO:0097190 268 0.011
autophagy GO:0006914 88 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
chemotaxis GO:0006935 157 0.011
regulation of hormone levels GO:0010817 125 0.011
response to food GO:0032094 1 0.011
cell fate determination GO:0001709 3 0.011
anion transport GO:0006820 161 0.011
neuron projection development GO:0031175 106 0.011
adult locomotory behavior GO:0008344 1 0.011
positive regulation of organelle organization GO:0010638 195 0.011
single organism nuclear import GO:1902593 104 0.011
memory GO:0007613 3 0.011
ectodermal cell fate specification GO:0001715 1 0.010
regulation of cell cycle GO:0051726 393 0.010
negative regulation of kidney development GO:0090185 2 0.010
single organism carbohydrate catabolic process GO:0044724 33 0.010
regulation of protein targeting GO:1903533 91 0.010
negative regulation of phosphorus metabolic process GO:0010563 267 0.010
cellular response to nutrient levels GO:0031669 69 0.010
positive regulation of icosanoid secretion GO:0032305 3 0.010
positive regulation of fatty acid transport GO:2000193 3 0.010
neurogenesis GO:0022008 169 0.010
hexose metabolic process GO:0019318 55 0.010
endocytosis GO:0006897 159 0.010
negative regulation of cellular component organization GO:0051129 235 0.010
regulation of secretion GO:0051046 194 0.010
cochlea development GO:0090102 1 0.010
regulation of protein serine threonine kinase activity GO:0071900 179 0.010
specification of symmetry GO:0009799 16 0.010
cilium dependent cell motility GO:0060285 4 0.010
carbohydrate catabolic process GO:0016052 36 0.010
retina layer formation GO:0010842 3 0.010
proteasomal protein catabolic process GO:0010498 176 0.010
microtubule anchoring at microtubule organizing center GO:0072393 1 0.010
monovalent inorganic cation transport GO:0015672 128 0.010
developmental programmed cell death GO:0010623 3 0.010
establishment of protein localization to organelle GO:0072594 172 0.010
regulation of receptor mediated endocytosis GO:0048259 32 0.010
negative regulation of cell motility GO:2000146 104 0.010
cellular metal ion homeostasis GO:0006875 146 0.010
circulatory system process GO:0003013 113 0.010
regulation of transferase activity GO:0051338 355 0.010
non canonical wnt signaling pathway via mapk cascade GO:0038030 4 0.010
pyridine nucleotide metabolic process GO:0019362 14 0.010
neural retina development GO:0003407 8 0.010

BBS7 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.068
nervous system disease DOID:863 431 0.068
eye and adnexa disease DOID:1492 150 0.048
musculoskeletal system disease DOID:17 223 0.039
eye disease DOID:5614 149 0.039
retinal disease DOID:5679 118 0.030
muscular disease DOID:0080000 114 0.020
myopathy DOID:423 104 0.018
muscle tissue disease DOID:66 113 0.018
connective tissue disease DOID:65 109 0.018
retinal degeneration DOID:8466 89 0.014
bone disease DOID:0080001 88 0.014
disease of metabolism DOID:0014667 295 0.011
cardiovascular system disease DOID:1287 106 0.011
muscular dystrophy DOID:9884 51 0.011