Homo sapiens

157 known processes

BCL2L1

BCL2-like 1

(Aliases: BCLXS,BCL-XL/S,bcl-xS,Bcl-X,BCLX,bcl-xL,BCL2L,BCLXL,DKFZp781P2092)

BCL2L1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of oxidative stress induced neuron death GO:1903203 9 1.000
Human
neuron death in response to oxidative stress GO:0036475 9 1.000
Human
positive regulation of endoplasmic reticulum unfolded protein response GO:1900103 4 1.000
Human
positive regulation of response to oxidative stress GO:1902884 7 1.000
Human
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 1.000
Human
positive regulation of release of cytochrome c from mitochondria GO:0090200 18 1.000
Human
positive regulation of apoptotic signaling pathway GO:2001235 70 1.000
Human
regulation of protein oligomerization GO:0032459 26 1.000
Human
positive regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903378 2 1.000
Human
regulation of apoptotic dna fragmentation GO:1902510 3 1.000
Human
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 20 1.000
Human
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 28 1.000
Human
modulation of programmed cell death in other organism involved in symbiotic interaction GO:0052248 1 1.000
positive regulation of mitochondrion organization GO:0010822 30 1.000
Human
modulation of programmed cell death in other organism GO:0044531 1 1.000
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903376 7 1.000
Human
regulation of release of cytochrome c from mitochondria GO:0090199 29 1.000
behavioral defense response GO:0002209 0 1.000
regulation of mitochondrion organization GO:0010821 54 1.000
regulation of protein heterodimerization activity GO:0043497 5 1.000
Human
negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction GO:0052490 1 1.000
negative regulation of calcium ion transport into cytosol GO:0010523 3 1.000
modulation by symbiont of host programmed cell death GO:0052040 1 1.000
mitochondrial fragmentation involved in apoptotic process GO:0043653 7 1.000
Human
modulation by symbiont of host apoptotic process GO:0052150 1 1.000
positive regulation of organelle organization GO:0010638 195 1.000
Human
apoptotic mitochondrial changes GO:0008637 57 1.000
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway GO:1901030 3 1.000
positive regulation of protein oligomerization GO:0032461 17 1.000
Human
regulation of cellular ph reduction GO:0032847 1 1.000
Human
pigment granule organization GO:0048753 7 1.000
fear response GO:0042596 0 1.000
positive regulation of oxidative stress induced cell death GO:1903209 5 1.000
Human
regulation of endoplasmic reticulum unfolded protein response GO:1900101 5 1.000
Human
positive regulation of apoptotic dna fragmentation GO:1902512 1 1.000
Human
positive regulation of cellular response to oxidative stress GO:1900409 7 1.000
Human
regulation of execution phase of apoptosis GO:1900117 11 1.000
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 1.000
positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902177 4 1.000
Human
modulation by symbiont of host cellular process GO:0044068 3 1.000
transformed cell apoptotic process GO:0006927 3 1.000
Human
modulation of apoptotic process in other organism GO:0044532 1 1.000
modulation by organism of apoptotic process in other organism involved in symbiotic interaction GO:0052433 1 1.000
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 21 1.000
Human
regulation of proteolysis GO:0030162 293 1.000
Human Zebrafish Rat
regulation of peptidase activity GO:0052547 180 1.000
Human Zebrafish Rat
negative regulation of execution phase of apoptosis GO:1900118 6 1.000
neuron intrinsic apoptotic signaling pathway in response to oxidative stress GO:0036480 7 1.000
Human
activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c GO:0008635 2 1.000
Human
regulation of mitochondrial fusion GO:0010635 5 1.000
positive regulation of cellular component organization GO:0051130 376 1.000
Human
hair follicle morphogenesis GO:0031069 2 1.000
apoptotic signaling pathway GO:0097190 268 1.000
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 1.000
Human
release of cytochrome c from mitochondria GO:0001836 35 1.000
zymogen activation GO:0031638 70 0.999
Human
extrinsic apoptotic signaling pathway GO:0097191 119 0.999
Human Mouse
positive regulation of execution phase of apoptosis GO:1900119 5 0.999
Human
regulation of cysteine type endopeptidase activity GO:2000116 127 0.999
Human Zebrafish Rat
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 22 0.999
Human Mouse
negative regulation of apoptotic signaling pathway GO:2001234 97 0.999
regulation of apoptotic signaling pathway GO:2001233 175 0.999
mitochondrial fusion GO:0008053 13 0.999
Human
negative regulation of apoptotic process GO:0043066 316 0.999
regulation of cellular component biogenesis GO:0044087 281 0.999
Human
negative regulation of programmed cell death GO:0043069 321 0.999
modulation by virus of host apoptotic process GO:0039526 1 0.999
positive regulation of cellular component biogenesis GO:0044089 158 0.999
Human
t cell homeostasis GO:0043029 3 0.999
positive regulation of proteolysis GO:0045862 142 0.999
Human
release of matrix enzymes from mitochondria GO:0032976 1 0.998
Human
b cell receptor apoptotic signaling pathway GO:1990117 1 0.998
Human
calcium ion transport GO:0006816 147 0.998
Human
protein processing GO:0016485 226 0.998
Human Zebrafish Rat
response to iron ion GO:0010039 6 0.998
Human
retinal cell apoptotic process GO:1990009 1 0.998
Human
modulation by virus of host process GO:0019054 2 0.998
regulation of mitochondrial membrane permeability GO:0046902 25 0.998
regulation of membrane permeability GO:0090559 25 0.998
single organism membrane fusion GO:0044801 37 0.997
Human
protein homooligomerization GO:0051260 100 0.997
Human
regulation of protein localization to plasma membrane GO:1903076 40 0.997
mitochondrion organization GO:0007005 156 0.997
regulation of endopeptidase activity GO:0052548 170 0.996
Human Zebrafish Rat
cellular response to mechanical stimulus GO:0071260 39 0.996
Human
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 16 0.996
Human
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.996
positive regulation of developmental pigmentation GO:0048087 2 0.995
cd8 positive alpha beta t cell differentiation GO:0043374 1 0.995
signal transduction in absence of ligand GO:0038034 22 0.995
Human Mouse
response to topologically incorrect protein GO:0035966 29 0.995
Human
regulation of transmembrane transporter activity GO:0022898 74 0.995
Human
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway GO:0001844 2 0.995
positive regulation of cell death GO:0010942 263 0.995
Human Mouse
positive regulation of oxidative stress induced neuron death GO:1903223 2 0.995
Human
plasma membrane organization GO:0007009 115 0.995
modulation by virus of host morphology or physiology GO:0019048 10 0.994
response to alkaloid GO:0043279 20 0.994
Human Mouse
positive regulation of endopeptidase activity GO:0010950 84 0.993
Human
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.993
Human
establishment of protein localization to plasma membrane GO:0090002 68 0.993
mitochondrial membrane organization GO:0007006 40 0.992
response to endoplasmic reticulum stress GO:0034976 49 0.992
Human
positive regulation of protein homooligomerization GO:0032464 7 0.992
cation homeostasis GO:0055080 189 0.992
Human
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 1 0.992
metal ion transport GO:0030001 272 0.992
Human
apoptotic process involved in morphogenesis GO:0060561 3 0.991
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.990
Human
establishment or maintenance of transmembrane electrochemical gradient GO:0010248 2 0.990
Human
cellular ion homeostasis GO:0006873 168 0.989
Human
apoptotic dna fragmentation GO:0006309 6 0.989
Human
negative regulation of establishment of protein localization to plasma membrane GO:0090005 9 0.989
regulation of oxidative stress induced cell death GO:1903201 24 0.989
Human
positive regulation of b cell proliferation GO:0030890 12 0.989
Human
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 12 0.989
Human
positive regulation of programmed cell death GO:0043068 249 0.989
Human Mouse
endomembrane system organization GO:0010256 196 0.987
single organism cellular localization GO:1902580 332 0.986
negative regulation of response to dna damage stimulus GO:2001021 33 0.986
membrane fusion GO:0061025 43 0.985
Human
negative regulation of signal transduction in absence of ligand GO:1901099 16 0.985
Human
modification of morphology or physiology of other organism GO:0035821 43 0.985
divalent inorganic cation transport GO:0072511 158 0.985
Human
behavioral fear response GO:0001662 0 0.983
cd4 positive or cd8 positive alpha beta t cell lineage commitment GO:0043369 1 0.983
intrinsic apoptotic signaling pathway GO:0097193 127 0.983
endoplasmic reticulum unfolded protein response GO:0030968 16 0.983
Human
immune response activating signal transduction GO:0002757 90 0.980
Human
positive regulation of myotube differentiation GO:0010831 3 0.980
mitochondrial transport GO:0006839 60 0.980
cytokinesis GO:0000910 96 0.979
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.979
Human
intracellular ph reduction GO:0051452 10 0.978
Human
cellular response to dna damage stimulus GO:0006974 379 0.977
regulation of cellular response to oxidative stress GO:1900407 26 0.976
Human
ion transmembrane transport GO:0034220 338 0.975
Human
response to nicotine GO:0035094 12 0.974
Human
monovalent inorganic cation homeostasis GO:0055067 37 0.970
Human
multicellular organismal response to stress GO:0033555 1 0.970
positive regulation of apoptotic process involved in morphogenesis GO:1902339 1 0.970
positive regulation of peptidase activity GO:0010952 88 0.969
Human
regulation of cell cycle process GO:0010564 266 0.969
cellular chemical homeostasis GO:0055082 180 0.968
Human
metencephalon development GO:0022037 2 0.965
negative regulation of binding GO:0051100 57 0.964
Human
regulation of membrane potential GO:0042391 95 0.964
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.963
execution phase of apoptosis GO:0097194 32 0.963
positive regulation of b cell activation GO:0050871 17 0.962
Human
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.962
Human
protein localization to plasma membrane GO:0072659 93 0.962
divalent inorganic cation homeostasis GO:0072507 136 0.962
endoplasmic reticulum calcium ion homeostasis GO:0032469 9 0.961
regulation of cellular amine metabolic process GO:0033238 11 0.960
activation of immune response GO:0002253 114 0.958
Human
ion homeostasis GO:0050801 230 0.954
Human
ph reduction GO:0045851 11 0.951
Human
positive regulation of kinase activity GO:0033674 204 0.947
cellular response to external stimulus GO:0071496 111 0.944
Human
positive regulation of apoptotic process GO:0043065 246 0.943
Human Mouse
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.943
Human Zebrafish Rat
cellular response to abiotic stimulus GO:0071214 117 0.943
Human Mouse
melanin metabolic process GO:0006582 1 0.942
negative regulation of intrinsic apoptotic signaling pathway in response to dna damage GO:1902230 18 0.942
positive regulation of catabolic process GO:0009896 310 0.942
Human
regulation of transporter activity GO:0032409 82 0.941
Human
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.940
b cell apoptotic process GO:0001783 6 0.938
Human
immune response regulating signaling pathway GO:0002764 97 0.936
Human
regulation of mitochondrial membrane potential GO:0051881 23 0.935
activation of cysteine type endopeptidase activity GO:0097202 57 0.934
Human
response to unfolded protein GO:0006986 24 0.933
Human
negative regulation of catalytic activity GO:0043086 335 0.931
Zebrafish Rat
positive regulation of protein complex assembly GO:0031334 86 0.931
Human
positive regulation of pigment cell differentiation GO:0050942 2 0.927
transmembrane transport GO:0055085 399 0.927
Human
lymphocyte apoptotic process GO:0070227 20 0.926
Human
regulation of mitotic cell cycle GO:0007346 189 0.926
cellular divalent inorganic cation homeostasis GO:0072503 128 0.926
nucleoside catabolic process GO:0009164 408 0.925
purine nucleoside catabolic process GO:0006152 398 0.924
positive regulation of cellular catabolic process GO:0031331 284 0.924
Human
negative regulation of protein binding GO:0032091 35 0.923
Human
organelle fusion GO:0048284 36 0.923
Human
regulation of intrinsic apoptotic signaling pathway in response to dna damage GO:1902229 20 0.922
b cell homeostasis GO:0001782 1 0.919
cellular ketone metabolic process GO:0042180 80 0.916
calcium ion transport into cytosol GO:0060402 48 0.916
leukocyte proliferation GO:0070661 74 0.915
Human
single organism membrane organization GO:0044802 268 0.914
cellular response to unfolded protein GO:0034620 16 0.912
Human
cytosolic calcium ion transport GO:0060401 48 0.912
antigen receptor mediated signaling pathway GO:0050851 38 0.911
Human
cellular calcium ion homeostasis GO:0006874 117 0.909
membrane organization GO:0061024 292 0.909
response to virus GO:0009615 126 0.907
Human Mouse
cellular response to oxidative stress GO:0034599 85 0.907
Human
multi organism cellular process GO:0044764 156 0.907
cell type specific apoptotic process GO:0097285 125 0.905
Human Mouse
regulation of cellular amino acid metabolic process GO:0006521 6 0.903
regulation of protein binding GO:0043393 66 0.902
Human
regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902108 18 0.901
growth GO:0040007 202 0.897
Human Mouse
protein ubiquitination GO:0016567 314 0.894
Human
response to electrical stimulus GO:0051602 1 0.894
Rat
positive regulation of neuron apoptotic process GO:0043525 8 0.893
Human
protein maturation GO:0051604 233 0.892
Human Zebrafish Rat
positive regulation of dna catabolic process GO:1903626 2 0.890
Human
response to inorganic substance GO:0010035 127 0.890
Human Rat
apoptotic nuclear changes GO:0030262 13 0.889
Human
cardiovascular system development GO:0072358 262 0.887
mitochondrial outer membrane permeabilization GO:0097345 15 0.877
regulation of glycoprotein biosynthetic process GO:0010559 14 0.877
cellular amine metabolic process GO:0044106 41 0.875
protein localization to membrane GO:0072657 160 0.873
guanosine containing compound catabolic process GO:1901069 239 0.872
response to oxidative stress GO:0006979 121 0.872
Human Rat
regulation of protein processing GO:0070613 150 0.871
Zebrafish Rat
interaction with host GO:0051701 42 0.863
response to radiation GO:0009314 151 0.861
Human Mouse
ribonucleoside triphosphate metabolic process GO:0009199 412 0.861
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.857
Human
cation transport GO:0006812 331 0.856
Human
modification by symbiont of host morphology or physiology GO:0044003 12 0.854
protein oligomerization GO:0051259 173 0.853
Human
viral process GO:0016032 146 0.844
response to cytokine GO:0034097 232 0.842
regulation of cellular ketone metabolic process GO:0010565 50 0.841
negative regulation of phosphatase activity GO:0010923 61 0.838
regulation of b cell proliferation GO:0030888 18 0.835
Human
er nucleus signaling pathway GO:0006984 23 0.835
Human
cellular response to topologically incorrect protein GO:0035967 19 0.833
Human
cellular component disassembly GO:0022411 92 0.831
Human
protein polyubiquitination GO:0000209 110 0.830
Human
positive regulation of phosphorylation GO:0042327 394 0.829
thymus development GO:0048538 3 0.828
negative regulation of protein metabolic process GO:0051248 391 0.824
Zebrafish Rat
t cell lineage commitment GO:0002360 1 0.823
negative regulation of cell death GO:0060548 345 0.817
positive regulation of mitochondrial membrane permeability GO:0035794 17 0.815
response to ionizing radiation GO:0010212 65 0.815
Mouse
regulation of response to oxidative stress GO:1902882 26 0.814
Human
release of sequestered calcium ion into cytosol GO:0051209 41 0.810
regulation of ion homeostasis GO:2000021 73 0.809
Human
t cell selection GO:0045058 4 0.809
negative regulation of protein maturation GO:1903318 142 0.804
Zebrafish Rat
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.804
post embryonic development GO:0009791 2 0.801
negative regulation of cellular protein metabolic process GO:0032269 353 0.794
Zebrafish Rat
negative regulation of neuron apoptotic process GO:0043524 23 0.793
Human Mouse
lymphocyte homeostasis GO:0002260 4 0.792
negative regulation of anoikis GO:2000811 15 0.791
mitochondrial fission GO:0000266 14 0.784
Human
glycosyl compound catabolic process GO:1901658 413 0.784
lymphocyte proliferation GO:0046651 70 0.780
Human
lymphoid progenitor cell differentiation GO:0002320 3 0.775
establishment of protein localization to mitochondrion GO:0072655 22 0.770
interspecies interaction between organisms GO:0044419 156 0.766
regulation of developmental pigmentation GO:0048070 2 0.765
tissue homeostasis GO:0001894 63 0.765
Zebrafish
cytoplasmic transport GO:0016482 379 0.763
positive regulation of leukocyte proliferation GO:0070665 48 0.761
Human
negative regulation of protein processing GO:0010955 142 0.753
Zebrafish Rat
regulation of calcium ion transport into cytosol GO:0010522 33 0.750
dna catabolic process GO:0006308 49 0.748
Human
negative regulation of cell cycle phase transition GO:1901988 89 0.747
regulation of neuron death GO:1901214 56 0.747
Human Mouse
positive regulation of hydrolase activity GO:0051345 331 0.746
Human
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.743
Human
oligodendrocyte differentiation GO:0048709 7 0.742
protein modification by small protein conjugation GO:0032446 342 0.742
Human
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 38 0.741
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.735
purine containing compound catabolic process GO:0072523 411 0.733
sequestering of metal ion GO:0051238 24 0.721
regulation of growth GO:0040008 165 0.717
Human
defense response to virus GO:0051607 71 0.716
Human
regulation of neuron apoptotic process GO:0043523 35 0.713
Human Mouse
hematopoietic progenitor cell differentiation GO:0002244 38 0.713
purine nucleotide catabolic process GO:0006195 405 0.713
negative regulation of proteolysis GO:0045861 132 0.712
Zebrafish Rat
chemical homeostasis GO:0048878 306 0.710
Human
epidermis morphogenesis GO:0048730 3 0.710
amine metabolic process GO:0009308 44 0.707
lymphocyte activation GO:0046649 133 0.705
Human
positive regulation of cell proliferation GO:0008284 301 0.704
Human Mouse
ribonucleoside catabolic process GO:0042454 406 0.702
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.696
limbic system development GO:0021761 3 0.695
cellular homeostasis GO:0019725 196 0.693
Human
positive regulation of cellular amine metabolic process GO:0033240 7 0.692
taxis GO:0042330 157 0.687
positive regulation of epithelial cell differentiation GO:0030858 14 0.687
response to gamma radiation GO:0010332 14 0.684
Mouse
regulation of protein homooligomerization GO:0032462 11 0.684
regulation of protein localization GO:0032880 296 0.682
positive regulation of cell growth GO:0030307 48 0.681
Human
mitotic cell cycle GO:0000278 326 0.680
positive regulation of transport GO:0051050 336 0.673
mitochondrial outer membrane permeabilization involved in programmed cell death GO:1902686 16 0.671
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.667
Human
cytosolic calcium ion homeostasis GO:0051480 89 0.662
regulation of b cell activation GO:0050864 24 0.661
Human
mitotic cell cycle phase transition GO:0044772 162 0.656
hair cycle GO:0042633 28 0.656
regulation of response to dna damage stimulus GO:2001020 94 0.652
regulation of binding GO:0051098 111 0.649
Human
regulation of cellular response to stress GO:0080135 244 0.647
osteoblast proliferation GO:0033687 8 0.647
regulation of dna catabolic process GO:1903624 7 0.645
Human
negative regulation of organelle organization GO:0010639 126 0.645
melanocyte differentiation GO:0030318 2 0.643
positive regulation of immune response GO:0050778 159 0.642
Human
positive regulation of dna metabolic process GO:0051054 73 0.640
Human
regulation of anoikis GO:2000209 19 0.639
positive regulation of striated muscle cell differentiation GO:0051155 9 0.631
actin filament based process GO:0030029 224 0.626
negative regulation of homeostatic process GO:0032845 59 0.622
Human
patterning of blood vessels GO:0001569 2 0.619
developmental programmed cell death GO:0010623 3 0.618
negative regulation of myeloid cell apoptotic process GO:0033033 4 0.616
positive regulation of skeletal muscle tissue development GO:0048643 1 0.616
response to organonitrogen compound GO:0010243 156 0.616
Human Mouse Rat
regulation of metal ion transport GO:0010959 120 0.616
Human
purine nucleoside triphosphate catabolic process GO:0009146 392 0.614
cellular response to uv GO:0034644 32 0.613
Human
anoikis GO:0043276 22 0.611
organophosphate catabolic process GO:0046434 430 0.609
positive regulation of muscle cell differentiation GO:0051149 15 0.607
regulation of ion transport GO:0043269 189 0.606
Human
positive regulation of developmental process GO:0051094 314 0.602
cellular component morphogenesis GO:0032989 314 0.600
Mouse
regulation of protein complex assembly GO:0043254 147 0.599
Human
positive regulation of immune system process GO:0002684 283 0.599
Human
regulation of cell activation GO:0050865 125 0.597
Human
regulation of glycoprotein metabolic process GO:1903018 19 0.597
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000059 3 0.595
sequestering of calcium ion GO:0051208 17 0.591
mitotic cell cycle checkpoint GO:0007093 68 0.590
negative regulation of release of cytochrome c from mitochondria GO:0090201 11 0.588
calcium ion homeostasis GO:0055074 122 0.583
gtp metabolic process GO:0046039 239 0.583
single organismal cell cell adhesion GO:0016337 148 0.582
regulation of leukocyte proliferation GO:0070663 67 0.578
Human
regulation of mononuclear cell proliferation GO:0032944 65 0.578
Human
cellular response to nutrient levels GO:0031669 69 0.576
negative regulation of peptidase activity GO:0010466 91 0.575
Zebrafish Rat
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.575
cell death in response to oxidative stress GO:0036473 29 0.574
Human
negative regulation of protein localization to plasma membrane GO:1903077 13 0.572
neuron apoptotic process GO:0051402 39 0.569
Human Mouse
immune response GO:0006955 307 0.565
Human
ribonucleoside triphosphate catabolic process GO:0009203 391 0.562
purine nucleoside triphosphate metabolic process GO:0009144 412 0.561
hemopoiesis GO:0030097 180 0.561
dephosphorylation GO:0016311 209 0.557
glomerulus development GO:0032835 15 0.549
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.545
organ morphogenesis GO:0009887 147 0.542
regulation of establishment of protein localization GO:0070201 242 0.538
cellular response to endogenous stimulus GO:0071495 336 0.529
Mouse
cell matrix adhesion GO:0007160 85 0.527
cellular metal ion homeostasis GO:0006875 146 0.526
regulation of calcium ion transport GO:0051924 79 0.526
Human
response to uv GO:0009411 73 0.524
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.523
regulation of pigment cell differentiation GO:0050932 2 0.520
response to copper ion GO:0046688 8 0.513
positive regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902110 16 0.511
leukocyte activation GO:0045321 164 0.510
Human
regulation of leukocyte activation GO:0002694 115 0.509
Human
negative regulation of mitochondrion organization GO:0010823 22 0.508
hematopoietic or lymphoid organ development GO:0048534 186 0.508
endocrine system development GO:0035270 26 0.505
Zebrafish
positive regulation of fibroblast apoptotic process GO:2000271 6 0.504
positive regulation of gtpase activity GO:0043547 166 0.502
positive regulation of neuron death GO:1901216 14 0.501
Human
cellular cation homeostasis GO:0030003 163 0.500
Human
peptidyl serine modification GO:0018209 106 0.498
mononuclear cell proliferation GO:0032943 71 0.497
Human
cellular component disassembly involved in execution phase of apoptosis GO:0006921 13 0.492
Human
positive regulation of leukocyte activation GO:0002696 80 0.492
Human
negative regulation of calcium ion transport GO:0051926 19 0.489
response to organic cyclic compound GO:0014070 204 0.483
Human Mouse Rat
divalent metal ion transport GO:0070838 152 0.482
Human
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.481
male sex differentiation GO:0046661 25 0.480
Mouse
ribonucleotide catabolic process GO:0009261 405 0.477
negative regulation of cellular amine metabolic process GO:0033239 3 0.475
regulation of cell growth GO:0001558 135 0.474
Human
regulation of anatomical structure morphogenesis GO:0022603 286 0.472
protein insertion into mitochondrial membrane GO:0051204 3 0.468
metal ion homeostasis GO:0055065 169 0.465
spleen development GO:0048536 1 0.464
nucleoside phosphate catabolic process GO:1901292 412 0.462
positive regulation of nucleoside metabolic process GO:0045979 186 0.457
regulation of synaptic plasticity GO:0048167 3 0.457
purine ribonucleoside catabolic process GO:0046130 398 0.453
regulation of gtp catabolic process GO:0033124 180 0.452
leukocyte differentiation GO:0002521 98 0.451
embryonic digit morphogenesis GO:0042733 6 0.445
epithelial cell differentiation GO:0030855 141 0.445
nucleoside triphosphate metabolic process GO:0009141 422 0.445
negative regulation of phosphate metabolic process GO:0045936 267 0.444
nucleoside triphosphate catabolic process GO:0009143 394 0.441
morphogenesis of a branching epithelium GO:0061138 20 0.439
cell activation GO:0001775 213 0.435
Human
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.432
Zebrafish Rat
defense response to other organism GO:0098542 129 0.432
Human
positive regulation of mononuclear cell proliferation GO:0032946 47 0.428
Human
anatomical structure formation involved in morphogenesis GO:0048646 284 0.428
positive regulation of growth GO:0045927 58 0.427
Human
response to caffeine GO:0031000 3 0.426
cell cell junction organization GO:0045216 69 0.425
regeneration GO:0031099 4 0.423
regulation of mitosis GO:0007088 63 0.422
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.416
Human
cell cycle checkpoint GO:0000075 117 0.410
female gamete generation GO:0007292 2 0.409
regulation of nucleoside metabolic process GO:0009118 209 0.408
glycoprotein biosynthetic process GO:0009101 91 0.408
positive regulation of nucleotide metabolic process GO:0045981 230 0.406
regulation of protein maturation GO:1903317 150 0.404
Zebrafish Rat
spermatid differentiation GO:0048515 4 0.403
purine ribonucleoside metabolic process GO:0046128 437 0.399
response to other organism GO:0051707 261 0.396
Human Mouse
apoptotic process involved in mammary gland involution GO:0060057 1 0.396
positive regulation of transferase activity GO:0051347 227 0.395
chordate embryonic development GO:0043009 34 0.395
Mouse
nucleotide catabolic process GO:0009166 408 0.393
brain development GO:0007420 97 0.391
response to metal ion GO:0010038 84 0.381
Human Rat
female gonad development GO:0008585 10 0.381
Mouse Rat
negative regulation of cellular component organization GO:0051129 235 0.381
regulation of protein ubiquitination GO:0031396 95 0.379
negative regulation of cell cycle process GO:0010948 121 0.378
regulation of mitotic cell cycle phase transition GO:1901990 118 0.374
neuron death GO:0070997 65 0.373
Human Mouse
posttranscriptional regulation of gene expression GO:0010608 213 0.373
negative regulation of phosphorus metabolic process GO:0010563 267 0.371
immune system development GO:0002520 195 0.370
regulation of cell cycle GO:0051726 393 0.369
response to transition metal nanoparticle GO:1990267 29 0.368
Human
cellular amino acid metabolic process GO:0006520 116 0.368
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.366
regulation of cell differentiation GO:0045595 393 0.365
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.361
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001269 1 0.360
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001241 4 0.360
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.358
ovarian follicle development GO:0001541 5 0.356
Mouse Rat
circulatory system development GO:0072359 262 0.354
response to toxic substance GO:0009636 37 0.350
Human
thymocyte apoptotic process GO:0070242 2 0.349
regulation of protein stability GO:0031647 87 0.348
positive regulation of nucleotide catabolic process GO:0030813 185 0.345
protein localization to organelle GO:0033365 280 0.344
modification dependent protein catabolic process GO:0019941 209 0.343
epithelial cell proliferation GO:0050673 128 0.343
leukocyte apoptotic process GO:0071887 31 0.340
Human
neuron projection regeneration GO:0031102 1 0.339
response to reactive oxygen species GO:0000302 61 0.336
Rat
negative regulation of sequestering of calcium ion GO:0051283 41 0.332
actin filament organization GO:0007015 128 0.331
lipid metabolic process GO:0006629 381 0.331
regulation of sequestering of calcium ion GO:0051282 41 0.331
response to oxygen containing compound GO:1901700 369 0.327
Mouse Rat
glial cell apoptotic process GO:0034349 7 0.326
pigmentation GO:0043473 22 0.325
response to abiotic stimulus GO:0009628 336 0.325
Human Mouse Rat
establishment of protein localization to membrane GO:0090150 121 0.324
gtp catabolic process GO:0006184 237 0.324
regulation of intracellular transport GO:0032386 195 0.324
dna catabolic process endonucleolytic GO:0000737 37 0.320
Human
purine ribonucleotide catabolic process GO:0009154 404 0.319
reactive oxygen species metabolic process GO:0072593 75 0.316
b cell activation GO:0042113 33 0.311
Human
cell part morphogenesis GO:0032990 137 0.308
Mouse
vacuole organization GO:0007033 44 0.307
regulation of nucleotide catabolic process GO:0030811 205 0.306
positive regulation of cell motility GO:2000147 177 0.305
central nervous system development GO:0007417 123 0.304
positive regulation of muscle organ development GO:0048636 7 0.303
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.302
ovulation cycle GO:0042698 9 0.299
Mouse Rat
branching morphogenesis of an epithelial tube GO:0048754 19 0.297
regulation of homeostatic process GO:0032844 121 0.295
Human
regulation of nucleotide metabolic process GO:0006140 269 0.293

BCL2L1 disease predictions

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 104 0.564
muscular disease DOID:0080000 114 0.564
heart disease DOID:114 68 0.564
cardiomyopathy DOID:0050700 50 0.564
dilated cardiomyopathy DOID:12930 32 0.564
intrinsic cardiomyopathy DOID:0060036 50 0.564
cardiovascular system disease DOID:1287 106 0.564
musculoskeletal system disease DOID:17 223 0.564
muscle tissue disease DOID:66 113 0.564