|
|
positive regulation of release of cytochrome c from mitochondria
|
GO:0090200 |
18 |
1.000
|
|
|
|
regulation of release of cytochrome c from mitochondria
|
GO:0090199 |
29 |
1.000
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
1.000
|
|
|
|
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
|
GO:1901030 |
3 |
1.000
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
35 |
1.000
|
|
|
|
regulation of protein oligomerization
|
GO:0032459 |
26 |
1.000
|
|
|
|
positive regulation of mitochondrion organization
|
GO:0010822 |
30 |
1.000
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
1.000
|
|
|
|
positive regulation of protein oligomerization
|
GO:0032461 |
17 |
1.000
|
|
|
|
regulation of oxidative stress induced neuron death
|
GO:1903203 |
9 |
0.999
|
|
|
|
neuron death in response to oxidative stress
|
GO:0036475 |
9 |
0.999
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
54 |
0.999
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
16 |
0.999
|
|
|
|
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
|
GO:0001844 |
2 |
0.999
|
|
|
|
positive regulation of oxidative stress induced cell death
|
GO:1903209 |
5 |
0.998
|
|
|
|
regulation of mitochondrial membrane permeability involved in apoptotic process
|
GO:1902108 |
18 |
0.997
|
Mouse |
|
|
mitochondrial membrane organization
|
GO:0007006 |
40 |
0.996
|
Mouse |
|
|
positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902177 |
4 |
0.996
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.996
|
|
|
|
regulation of membrane permeability
|
GO:0090559 |
25 |
0.995
|
Mouse |
|
|
zymogen activation
|
GO:0031638 |
70 |
0.994
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.994
|
|
|
|
positive regulation of endoplasmic reticulum unfolded protein response
|
GO:1900103 |
4 |
0.993
|
|
|
|
modulation by virus of host morphology or physiology
|
GO:0019048 |
10 |
0.992
|
Mouse |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.991
|
Mouse |
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
20 |
0.990
|
|
|
|
positive regulation of response to oxidative stress
|
GO:1902884 |
7 |
0.990
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.990
|
|
|
|
regulation of mitochondrial membrane permeability
|
GO:0046902 |
25 |
0.989
|
Mouse |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.989
|
|
|
|
positive regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway
|
GO:1903378 |
2 |
0.988
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.988
|
|
|
|
mitochondrial transport
|
GO:0006839 |
60 |
0.987
|
Mouse |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.982
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.981
|
|
|
|
positive regulation of mitochondrial membrane permeability
|
GO:0035794 |
17 |
0.980
|
Mouse |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.978
|
|
|
|
modulation by symbiont of host apoptotic process
|
GO:0052150 |
1 |
0.978
|
Mouse |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.976
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.974
|
|
|
|
positive regulation of protein homooligomerization
|
GO:0032464 |
7 |
0.971
|
|
|
|
regulation of execution phase of apoptosis
|
GO:1900117 |
11 |
0.970
|
|
|
|
mitochondrial outer membrane permeabilization
|
GO:0097345 |
15 |
0.970
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.970
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
22 |
0.970
|
Mouse |
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.969
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.965
|
|
|
|
mitochondrial outer membrane permeabilization involved in programmed cell death
|
GO:1902686 |
16 |
0.964
|
Mouse |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.963
|
|
|
|
mitochondrial fragmentation involved in apoptotic process
|
GO:0043653 |
7 |
0.962
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.960
|
|
|
|
modulation of programmed cell death in other organism involved in symbiotic interaction
|
GO:0052248 |
1 |
0.960
|
Mouse |
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.957
|
|
|
|
neuron intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0036480 |
7 |
0.954
|
|
|
|
regulation of endoplasmic reticulum unfolded protein response
|
GO:1900101 |
5 |
0.953
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.951
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.948
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.948
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
21 |
0.947
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.945
|
|
|
|
positive regulation of cellular response to oxidative stress
|
GO:1900409 |
7 |
0.944
|
|
|
|
modulation of programmed cell death in other organism
|
GO:0044531 |
1 |
0.941
|
Mouse |
|
|
modulation of apoptotic process in other organism
|
GO:0044532 |
1 |
0.940
|
Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.940
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.940
|
|
|
|
modification by symbiont of host morphology or physiology
|
GO:0044003 |
12 |
0.936
|
Mouse |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.936
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.930
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.928
|
|
|
|
modulation by organism of apoptotic process in other organism involved in symbiotic interaction
|
GO:0052433 |
1 |
0.926
|
Mouse |
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.925
|
|
|
|
establishment of protein localization to mitochondrion
|
GO:0072655 |
22 |
0.924
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
8 |
0.923
|
Mouse |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.923
|
|
|
|
protein insertion into mitochondrial membrane
|
GO:0051204 |
3 |
0.923
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.921
|
Mouse |
|
|
t cell homeostasis
|
GO:0043029 |
3 |
0.921
|
Mouse |
|
|
regulation of cellular ph reduction
|
GO:0032847 |
1 |
0.920
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.915
|
|
|
|
modulation by symbiont of host cellular process
|
GO:0044068 |
3 |
0.908
|
Mouse |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.905
|
|
|
|
regulation of response to oxidative stress
|
GO:1902882 |
26 |
0.902
|
|
|
|
regulation of protein heterodimerization activity
|
GO:0043497 |
5 |
0.902
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.901
|
Mouse |
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.899
|
|
|
|
regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902175 |
16 |
0.896
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.895
|
|
|
|
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway
|
GO:1903376 |
7 |
0.893
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.893
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.891
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.889
|
|
|
|
execution phase of apoptosis
|
GO:0097194 |
32 |
0.888
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
22 |
0.883
|
Mouse |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.881
|
|
|
|
modulation by virus of host process
|
GO:0019054 |
2 |
0.874
|
Mouse |
|
|
single organism membrane fusion
|
GO:0044801 |
37 |
0.866
|
|
|
|
mitochondrial fission
|
GO:0000266 |
14 |
0.863
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.862
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c
|
GO:0008635 |
2 |
0.862
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.862
|
|
|
|
monovalent inorganic cation homeostasis
|
GO:0055067 |
37 |
0.861
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.859
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.856
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.853
|
|
|
|
regulation of oxidative stress induced cell death
|
GO:1903201 |
24 |
0.852
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.850
|
|
|
|
regulation of mitochondrial fusion
|
GO:0010635 |
5 |
0.844
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.844
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
33 |
0.842
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.841
|
|
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
26 |
0.841
|
|
|
|
negative regulation of anoikis
|
GO:2000811 |
15 |
0.835
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.834
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.833
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.827
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.823
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.814
|
|
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.812
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.807
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.805
|
|
|
|
apoptotic process involved in morphogenesis
|
GO:0060561 |
3 |
0.789
|
Mouse |
|
|
modulation by symbiont of host programmed cell death
|
GO:0052040 |
1 |
0.782
|
Mouse |
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
0.778
|
|
|
|
positive regulation of apoptotic process involved in mammary gland involution
|
GO:0060058 |
1 |
0.776
|
|
|
|
regulation of apoptotic dna fragmentation
|
GO:1902510 |
3 |
0.776
|
|
|
|
response to nicotine
|
GO:0035094 |
12 |
0.774
|
|
|
|
negative regulation of execution phase of apoptosis
|
GO:1900118 |
6 |
0.772
|
|
|
|
positive regulation of apoptotic process involved in morphogenesis
|
GO:1902339 |
1 |
0.769
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.764
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.764
|
|
|
|
er nucleus signaling pathway
|
GO:0006984 |
23 |
0.757
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.756
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.754
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.754
|
Mouse |
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.749
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.746
|
Mouse |
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.737
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.737
|
|
|
|
positive regulation of execution phase of apoptosis
|
GO:1900119 |
5 |
0.730
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.721
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.715
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.708
|
|
|
|
regulation of mitochondrial membrane potential
|
GO:0051881 |
23 |
0.700
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.695
|
|
|
|
endoplasmic reticulum unfolded protein response
|
GO:0030968 |
16 |
0.691
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.688
|
|
|
|
mitochondrial fusion
|
GO:0008053 |
13 |
0.683
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.682
|
|
|
|
positive regulation of mitochondrial membrane permeability involved in apoptotic process
|
GO:1902110 |
16 |
0.676
|
Mouse |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.675
|
|
|
|
positive regulation of oxidative stress induced neuron death
|
GO:1903223 |
2 |
0.670
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.661
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.658
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.653
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.651
|
|
|
|
regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
|
GO:1901028 |
9 |
0.651
|
|
|
|
response to alkaloid
|
GO:0043279 |
20 |
0.646
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
20 |
0.646
|
Mouse |
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
3 |
0.644
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.641
|
|
|
|
protein insertion into membrane
|
GO:0051205 |
9 |
0.635
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.634
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.633
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
43 |
0.629
|
Mouse |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.623
|
|
|
|
membrane fusion
|
GO:0061025 |
43 |
0.619
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
14 |
0.618
|
Mouse |
|
|
organelle fusion
|
GO:0048284 |
36 |
0.617
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.607
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.604
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.603
|
|
|
|
negative regulation of signal transduction in absence of ligand
|
GO:1901099 |
16 |
0.596
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.594
|
|
|
|
transformed cell apoptotic process
|
GO:0006927 |
3 |
0.590
|
|
|
|
retinal cell apoptotic process
|
GO:1990009 |
1 |
0.586
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.582
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.578
|
|
|
|
negative regulation of calcium ion transport into cytosol
|
GO:0010523 |
3 |
0.570
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.570
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.569
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.568
|
|
|
|
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
|
GO:0070059 |
12 |
0.564
|
Zebrafish |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.562
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.562
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.560
|
Mouse |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.559
|
|
|
|
response to unfolded protein
|
GO:0006986 |
24 |
0.558
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.554
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.553
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.548
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.547
|
|
|
|
negative regulation of mitochondrion organization
|
GO:0010823 |
22 |
0.542
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.540
|
|
|
|
cellular response to unfolded protein
|
GO:0034620 |
16 |
0.538
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.538
|
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.537
|
|
|
|
negative regulation by symbiont of host programmed cell death
|
GO:0052041 |
1 |
0.536
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.533
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.525
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.520
|
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
29 |
0.506
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.504
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.502
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.500
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.499
|
|
|
|
positive regulation of developmental pigmentation
|
GO:0048087 |
2 |
0.485
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.482
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.477
|
Mouse |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.461
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.461
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.459
|
Mouse |
|
|
patterning of blood vessels
|
GO:0001569 |
2 |
0.457
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.455
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.455
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.447
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.446
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.444
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.444
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.440
|
Mouse |
|
|
response to radiation
|
GO:0009314 |
151 |
0.439
|
|
|
|
regulation of sequestering of calcium ion
|
GO:0051282 |
41 |
0.438
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.436
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.424
|
Mouse |
|
|
anoikis
|
GO:0043276 |
22 |
0.423
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.422
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.418
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.416
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.416
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.412
|
|
|
|
positive regulation of dna catabolic process
|
GO:1903626 |
2 |
0.411
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.408
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.405
|
|
|
|
response to salt stress
|
GO:0009651 |
3 |
0.401
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.400
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.400
|
|
|
|
negative regulation by symbiont of host apoptotic process
|
GO:0033668 |
1 |
0.400
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.398
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.396
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.394
|
Mouse |
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.390
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.384
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
40 |
0.378
|
|
|
|
regulation of cellular ph
|
GO:0030641 |
17 |
0.371
|
|
|
|
establishment or maintenance of transmembrane electrochemical gradient
|
GO:0010248 |
2 |
0.370
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.367
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.361
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.358
|
|
|
|
negative regulation of establishment of protein localization to plasma membrane
|
GO:0090005 |
9 |
0.358
|
|
|
|
behavioral defense response
|
GO:0002209 |
0 |
0.355
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.354
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.352
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.346
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.340
|
Mouse |
|
|
response to metal ion
|
GO:0010038 |
84 |
0.339
|
|
|
|
dna catabolic process endonucleolytic
|
GO:0000737 |
37 |
0.339
|
|
|
|
regulation of anoikis
|
GO:2000209 |
19 |
0.339
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.338
|
Mouse |
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
23 |
0.337
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.332
|
Mouse |
|
|
b cell proliferation
|
GO:0042100 |
22 |
0.332
|
|
|
|
negative regulation of response to dna damage stimulus
|
GO:2001021 |
33 |
0.331
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.330
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.329
|
|
|
|
regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902041 |
24 |
0.328
|
|
|
|
protein localization to mitochondrion
|
GO:0070585 |
25 |
0.328
|
|
|
|
modulation by virus of host apoptotic process
|
GO:0039526 |
1 |
0.327
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.322
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.320
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.317
|
|
|
|
negative regulation of endoplasmic reticulum calcium ion concentration
|
GO:0032471 |
6 |
0.308
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
17 |
0.301
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.299
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.296
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.296
|
Mouse |
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.294
|
|
|
|
positive regulation of apoptotic dna fragmentation
|
GO:1902512 |
1 |
0.290
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.285
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.285
|
Mouse |
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.283
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.282
|
|
|
|
negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction
|
GO:0052490 |
1 |
0.281
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.280
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.279
|
|
|
|
release of matrix enzymes from mitochondria
|
GO:0032976 |
1 |
0.275
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.275
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.274
|
Mouse |
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.270
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.269
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.268
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.266
|
|
|
|
ph reduction
|
GO:0045851 |
11 |
0.266
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.265
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.264
|
|
|
|
growth
|
GO:0040007 |
202 |
0.261
|
Mouse |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.261
|
|
|
|
head development
|
GO:0060322 |
108 |
0.257
|
|
|
|
regulation of protein homodimerization activity
|
GO:0043496 |
9 |
0.257
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.257
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.256
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.254
|
|
|
|
fear response
|
GO:0042596 |
0 |
0.254
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.252
|
Mouse |
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.251
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.249
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.248
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.244
|
Mouse |
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.243
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.241
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.241
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.239
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.239
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.239
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.237
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.235
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.235
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.233
|
|
|
|
regulation of developmental pigmentation
|
GO:0048070 |
2 |
0.230
|
Mouse |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.229
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.228
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.227
|
|
|
|
modification of morphology or physiology of other organism involved in symbiotic interaction
|
GO:0051817 |
38 |
0.227
|
Mouse |
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.224
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.223
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.223
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.217
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.217
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.216
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.215
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.211
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
12 |
0.211
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.211
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.210
|
|
|
|
cellular response to topologically incorrect protein
|
GO:0035967 |
19 |
0.209
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.208
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.207
|
|
|
|
regulation of intracellular ph
|
GO:0051453 |
16 |
0.206
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.206
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.205
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.204
|
|
|
|
neural tube patterning
|
GO:0021532 |
2 |
0.204
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
32 |
0.200
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.200
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.200
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.197
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.197
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.197
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.194
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.191
|
|
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.190
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.189
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.188
|
|
|
|
regulation of apoptotic process involved in morphogenesis
|
GO:1902337 |
1 |
0.188
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.187
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.185
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.184
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.182
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.182
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001269 |
1 |
0.182
|
|
|
|
apoptotic dna fragmentation
|
GO:0006309 |
6 |
0.178
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.178
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.177
|
Mouse |
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.176
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.175
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.174
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.174
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.173
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.172
|
|
|
|
cellular response to light stimulus
|
GO:0071482 |
34 |
0.168
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.168
|
Mouse |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.168
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.166
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.165
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.164
|
Mouse |
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.163
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.163
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.162
|
|
|
|
regulation of intrinsic apoptotic signaling pathway in response to dna damage
|
GO:1902229 |
20 |
0.161
|
|
|
|
apoptotic nuclear changes
|
GO:0030262 |
13 |
0.160
|
|
|
|
b cell apoptotic process
|
GO:0001783 |
6 |
0.160
|
Mouse |
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.158
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.155
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.154
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.154
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.154
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.153
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.151
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.150
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.149
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.148
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.147
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.147
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.146
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.146
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.145
|
|
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.144
|
Mouse |
|
|
response to starvation
|
GO:0042594 |
59 |
0.143
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.143
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.143
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.142
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
18 |
0.141
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.141
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.140
|
Mouse |
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
32 |
0.140
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.139
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.138
|
|
|
|
cellular component disassembly involved in execution phase of apoptosis
|
GO:0006921 |
13 |
0.137
|
|
|
|
suppression by virus of host apoptotic process
|
GO:0019050 |
1 |
0.137
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
15 |
0.136
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.134
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.134
|
Mouse |
|
|
hypothalamus development
|
GO:0021854 |
1 |
0.133
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.133
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
33 |
0.132
|
|
|
|
positive regulation of glucose metabolic process
|
GO:0010907 |
12 |
0.132
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.131
|
|
|
|
response to transition metal nanoparticle
|
GO:1990267 |
29 |
0.130
|
|
|
|
regulation of b cell apoptotic process
|
GO:0002902 |
5 |
0.126
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.123
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
18 |
0.120
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.119
|
|
|
|
regulation of ph
|
GO:0006885 |
20 |
0.119
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
47 |
0.119
|
|
|
|
positive regulation of carbohydrate metabolic process
|
GO:0045913 |
21 |
0.119
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.118
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.118
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.116
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.116
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.114
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.114
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.113
|
|
|
|
response to topologically incorrect protein
|
GO:0035966 |
29 |
0.112
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
7 |
0.111
|
Mouse |
|
|
cell activation
|
GO:0001775 |
213 |
0.111
|
|
|
|
regulation of glucose metabolic process
|
GO:0010906 |
28 |
0.111
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.111
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.110
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.110
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.110
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.109
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.107
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.106
|
|
|
|
pigment granule organization
|
GO:0048753 |
7 |
0.106
|
|
|
|
negative regulation of fibroblast proliferation
|
GO:0048147 |
12 |
0.105
|
|
|
|
positive regulation of dna damage response signal transduction by p53 class mediator
|
GO:0043517 |
8 |
0.105
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.105
|
Mouse |
|
|
negative regulation of sequestering of calcium ion
|
GO:0051283 |
41 |
0.102
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.101
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.100
|
|
|
|
positive regulation of b cell apoptotic process
|
GO:0002904 |
1 |
0.098
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.096
|
|
|
|
negative regulation of protein binding
|
GO:0032091 |
35 |
0.096
|
|
|
|
dna catabolic process
|
GO:0006308 |
49 |
0.095
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.094
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.093
|
|
|
|
hexose metabolic process
|
GO:0019318 |
55 |
0.092
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
24 |
0.092
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.091
|
Mouse |
|
|
apoptotic process involved in mammary gland involution
|
GO:0060057 |
1 |
0.091
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.090
|
|
|
|
interaction with host
|
GO:0051701 |
42 |
0.089
|
Mouse |
|
|
vasculature development
|
GO:0001944 |
181 |
0.088
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.087
|
Mouse |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.087
|
|
|
|
regulation of protein homooligomerization
|
GO:0032462 |
11 |
0.084
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.084
|
|
|
|
cerebral cortex development
|
GO:0021987 |
10 |
0.084
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.084
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.083
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.083
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.083
|
|
|
|
b cell receptor apoptotic signaling pathway
|
GO:1990117 |
1 |
0.082
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.081
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.081
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
41 |
0.081
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.080
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.079
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.079
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.079
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.078
|
|
|
|
response to iron ion
|
GO:0010039 |
6 |
0.078
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.077
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.077
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.076
|
|
|
|
b cell homeostasis
|
GO:0001782 |
1 |
0.076
|
Mouse |
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.075
|
Mouse |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.075
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.075
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.074
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001267 |
2 |
0.074
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.073
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.071
|
|
|
|
blood vessel remodeling
|
GO:0001974 |
2 |
0.071
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.070
|
Mouse |
|
|
cellular monovalent inorganic cation homeostasis
|
GO:0030004 |
26 |
0.070
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.070
|
|
