Homo sapiens

19 known processes

BFAR

bifunctional apoptosis regulator

(Aliases: RNF47,BAR)

BFAR biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein polyubiquitination GO:0000209 110 0.787
protein autoubiquitination GO:0051865 37 0.725
protein modification by small protein conjugation GO:0032446 342 0.593
protein ubiquitination GO:0016567 314 0.435
ubiquitin dependent protein catabolic process GO:0006511 206 0.263
cellular protein catabolic process GO:0044257 261 0.236
modification dependent protein catabolic process GO:0019941 209 0.221
proteasomal protein catabolic process GO:0010498 176 0.211
cellular macromolecule catabolic process GO:0044265 380 0.187
protein k48 linked ubiquitination GO:0070936 38 0.161
protein catabolic process GO:0030163 325 0.159
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.141
modification dependent macromolecule catabolic process GO:0043632 212 0.133
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.127
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.105
protein monoubiquitination GO:0006513 39 0.100
protein maturation GO:0051604 233 0.061
histone ubiquitination GO:0016574 31 0.053
regulation of proteolysis GO:0030162 293 0.049
regulation of cell cycle GO:0051726 393 0.049
protein k63 linked ubiquitination GO:0070534 31 0.047
post embryonic development GO:0009791 2 0.045
ion transmembrane transport GO:0034220 338 0.043
negative regulation of programmed cell death GO:0043069 321 0.036
regulation of cellular response to stress GO:0080135 244 0.034
positive regulation of cell death GO:0010942 263 0.034
cellular amino acid metabolic process GO:0006520 116 0.033
segmentation GO:0035282 4 0.032
positive regulation of viral entry into host cell GO:0046598 3 0.032
interspecies interaction between organisms GO:0044419 156 0.031
regulation of protein localization GO:0032880 296 0.030
protein processing GO:0016485 226 0.029
metal ion transport GO:0030001 272 0.029
regulation of viral release from host cell GO:1902186 20 0.028
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.028
regulation of endopeptidase activity GO:0052548 170 0.028
amine metabolic process GO:0009308 44 0.028
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.027
regulation of response to external stimulus GO:0032101 222 0.027
regulation of peptidase activity GO:0052547 180 0.027
wnt signaling pathway GO:0016055 156 0.027
memory GO:0007613 3 0.027
negative regulation of protein metabolic process GO:0051248 391 0.027
cation transport GO:0006812 331 0.027
response to radiation GO:0009314 151 0.026
apoptotic signaling pathway GO:0097190 268 0.026
posttranscriptional regulation of gene expression GO:0010608 213 0.026
organelle assembly GO:0070925 176 0.026
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.026
negative regulation of calcium ion import GO:0090281 1 0.025
positive regulation of protein ubiquitination GO:0031398 53 0.025
positive regulation of catabolic process GO:0009896 310 0.024
regulation of transferase activity GO:0051338 355 0.024
regulation of cysteine type endopeptidase activity GO:2000116 127 0.024
positive regulation of organelle organization GO:0010638 195 0.024
multicellular organismal aging GO:0010259 3 0.024
system process GO:0003008 349 0.024
negative regulation of cell death GO:0060548 345 0.023
negative regulation of cell proliferation GO:0008285 228 0.023
negative regulation of cell cycle GO:0045786 193 0.023
transmembrane transport GO:0055085 399 0.023
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 32 0.023
negative regulation of cellular protein metabolic process GO:0032269 353 0.023
response to bacterium GO:0009617 144 0.022
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.022
positive regulation of programmed cell death GO:0043068 249 0.022
cellular protein complex assembly GO:0043623 188 0.022
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.022
morphogenesis of embryonic epithelium GO:0016331 4 0.022
negative regulation of apoptotic process GO:0043066 316 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
response to oxygen containing compound GO:1901700 369 0.021
negative regulation of catalytic activity GO:0043086 335 0.021
positive regulation of cellular component organization GO:0051130 376 0.021
positive regulation of apoptotic process GO:0043065 246 0.021
single organism membrane organization GO:0044802 268 0.021
regulation of locomotion GO:0040012 329 0.021
meiotic chromosome segregation GO:0045132 4 0.020
female gamete generation GO:0007292 2 0.020
actin filament based process GO:0030029 224 0.020
oogenesis GO:0048477 2 0.020
positive regulation of cytokine production GO:0001819 167 0.019
regulation of apoptotic signaling pathway GO:2001233 175 0.019
spinal cord development GO:0021510 4 0.019
somitogenesis GO:0001756 2 0.019
negative regulation of proteolysis GO:0045861 132 0.019
androgen receptor signaling pathway GO:0030521 34 0.019
hindbrain development GO:0030902 3 0.019
response to abiotic stimulus GO:0009628 336 0.019
cellular response to dna damage stimulus GO:0006974 379 0.019
negative regulation of hydrolase activity GO:0051346 182 0.019
positive regulation of transport GO:0051050 336 0.019
retrograde transport endosome to golgi GO:0042147 45 0.019
positive regulation of immune system process GO:0002684 283 0.019
actin cytoskeleton organization GO:0030036 207 0.019
regulation of kinase activity GO:0043549 314 0.019
regulation of cell cycle process GO:0010564 266 0.018
regulation of interleukin 2 secretion GO:1900040 2 0.018
negative regulation of cell differentiation GO:0045596 171 0.018
determination of adult lifespan GO:0008340 2 0.018
anterior posterior axis specification GO:0009948 2 0.018
embryonic epithelial tube formation GO:0001838 4 0.018
regulation of protein transport GO:0051223 213 0.018
cellular response to misfolded protein GO:0071218 2 0.018
multi organism cellular process GO:0044764 156 0.018
response to external biotic stimulus GO:0043207 261 0.017
regulation of intracellular transport GO:0032386 195 0.017
innate immune response GO:0045087 178 0.017
negative regulation of protein maturation GO:1903318 142 0.017
cellular ketone metabolic process GO:0042180 80 0.017
regulation of protein ubiquitination GO:0031396 95 0.017
positive regulation of proteolysis GO:0045862 142 0.017
ubiquitin dependent smad protein catabolic process GO:0030579 4 0.017
protein k11 linked ubiquitination GO:0070979 24 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.017
regulation of viral process GO:0050792 103 0.017
regulation of protein stability GO:0031647 87 0.017
positive regulation of cellular catabolic process GO:0031331 284 0.016
regulation of cell differentiation GO:0045595 393 0.016
negative regulation of multicellular organismal process GO:0051241 317 0.016
regulation of anatomical structure morphogenesis GO:0022603 286 0.016
negative regulation of developmental process GO:0051093 247 0.016
interaction with host GO:0051701 42 0.016
immune response GO:0006955 307 0.016
interleukin 2 secretion GO:0070970 3 0.016
cerebral cortex radially oriented cell migration GO:0021799 1 0.016
vesicle mediated transport GO:0016192 371 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.016
regulation of protein processing GO:0070613 150 0.016
canonical wnt signaling pathway GO:0060070 116 0.016
divalent inorganic cation transport GO:0072511 158 0.016
lipid metabolic process GO:0006629 381 0.016
i kappab kinase nf kappab signaling GO:0007249 166 0.015
response to virus GO:0009615 126 0.015
negative regulation of protein processing GO:0010955 142 0.015
intrinsic apoptotic signaling pathway GO:0097193 127 0.015
regulation of protein maturation GO:1903317 150 0.015
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000059 3 0.015
mitochondrion organization GO:0007005 156 0.015
response to biotic stimulus GO:0009607 276 0.015
protein oligomerization GO:0051259 173 0.015
positive regulation of transferase activity GO:0051347 227 0.015
microtubule cytoskeleton organization GO:0000226 176 0.015
nerve development GO:0021675 4 0.015
lipid biosynthetic process GO:0008610 177 0.015
mitotic cell cycle process GO:1903047 286 0.015
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.015
negative regulation of transport GO:0051051 176 0.015
oocyte differentiation GO:0009994 2 0.015
response to other organism GO:0051707 261 0.015
oocyte development GO:0048599 1 0.015
regulation of cytoskeleton organization GO:0051493 177 0.015
neurological system process GO:0050877 163 0.015
carbohydrate derivative biosynthetic process GO:1901137 207 0.015
negative regulation of interleukin 2 secretion GO:1900041 2 0.015
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.015
blastoderm segmentation GO:0007350 2 0.015
positive regulation of phosphorylation GO:0042327 394 0.015
organophosphate biosynthetic process GO:0090407 163 0.015
membrane organization GO:0061024 292 0.015
microtubule based process GO:0007017 210 0.015
response to extracellular stimulus GO:0009991 85 0.015
protein localization to organelle GO:0033365 280 0.014
regulation of cellular ketone metabolic process GO:0010565 50 0.014
cellular macromolecular complex assembly GO:0034622 324 0.014
reactive oxygen species metabolic process GO:0072593 75 0.014
response to organic cyclic compound GO:0014070 204 0.014
mitotic cell cycle GO:0000278 326 0.014
response to lipid GO:0033993 206 0.014
mrna metabolic process GO:0016071 175 0.014
negative regulation of organelle organization GO:0010639 126 0.014
regulation of protein kinase activity GO:0045859 289 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
ribonucleoside triphosphate catabolic process GO:0009203 391 0.014
regeneration GO:0031099 4 0.014
reactive nitrogen species metabolic process GO:2001057 3 0.014
negative regulation of glial cell proliferation GO:0060253 2 0.014
regulation of canonical wnt signaling pathway GO:0060828 88 0.014
locomotory behavior GO:0007626 1 0.014
regulation of protein catabolic process GO:0042176 155 0.014
vacuole organization GO:0007033 44 0.014
regulation of cellular amino acid metabolic process GO:0006521 6 0.014
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.014
negative regulation of cellular catabolic process GO:0031330 83 0.014
negative regulation of apoptotic signaling pathway GO:2001234 97 0.013
neural tube formation GO:0001841 3 0.013
organic acid biosynthetic process GO:0016053 97 0.013
negative regulation of cell cycle process GO:0010948 121 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
regulation of cellular amine metabolic process GO:0033238 11 0.013
meiosis i GO:0007127 4 0.013
neuromuscular junction development GO:0007528 3 0.013
single organism cellular localization GO:1902580 332 0.013
motor neuron axon guidance GO:0008045 2 0.013
regulation of cell development GO:0060284 161 0.013
regulation of autophagy GO:0010506 52 0.013
ras protein signal transduction GO:0007265 73 0.013
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.013
regulation of protein secretion GO:0050708 86 0.013
spermatid differentiation GO:0048515 4 0.013
regulation of cytokine production GO:0001817 232 0.013
response to ionizing radiation GO:0010212 65 0.013
regulation of secretion by cell GO:1903530 177 0.013
negative regulation of cellular component organization GO:0051129 235 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.013
regulation of establishment of protein localization GO:0070201 242 0.013
zymogen activation GO:0031638 70 0.013
cellular lipid metabolic process GO:0044255 303 0.013
reactive oxygen species biosynthetic process GO:1903409 4 0.013
cellular component morphogenesis GO:0032989 314 0.013
small molecule biosynthetic process GO:0044283 157 0.013
small gtpase mediated signal transduction GO:0007264 78 0.012
cytokine production GO:0001816 247 0.012
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
peripheral nervous system development GO:0007422 2 0.012
positive regulation of cellular amine metabolic process GO:0033240 7 0.012
defense response to virus GO:0051607 71 0.012
endomembrane system organization GO:0010256 196 0.012
regulation of ion transport GO:0043269 189 0.012
regulation of organelle assembly GO:1902115 40 0.012
negative regulation of phosphorylation GO:0042326 174 0.012
negative regulation of ion transport GO:0043271 39 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.012
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 10 0.012
regulation of mitotic cell cycle phase transition GO:1901990 118 0.012
nitrogen compound transport GO:0071705 191 0.012
cellular amine metabolic process GO:0044106 41 0.012
negative regulation of phosphate metabolic process GO:0045936 267 0.012
organophosphate catabolic process GO:0046434 430 0.012
cell development GO:0048468 328 0.012
nervous system development GO:0007399 293 0.012
calcium ion transport GO:0006816 147 0.012
regulation of multi organism process GO:0043900 157 0.012
rna processing GO:0006396 255 0.012
signal transduction by phosphorylation GO:0023014 297 0.012
tripartite regional subdivision GO:0007351 2 0.012
rab protein signal transduction GO:0032482 4 0.012
negative regulation of kinase activity GO:0033673 106 0.012
positive regulation of cellular component biogenesis GO:0044089 158 0.012
fatty acid metabolic process GO:0006631 115 0.012
regulation of microtubule based process GO:0032886 74 0.012
anterior posterior axis specification embryo GO:0008595 2 0.012
secretion GO:0046903 254 0.012
adult locomotory behavior GO:0008344 1 0.012
regulation of mitotic cell cycle GO:0007346 189 0.012
cellular response to topologically incorrect protein GO:0035967 19 0.012
negative regulation of gliogenesis GO:0014014 3 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.012
limbic system development GO:0021761 3 0.011
negative regulation of endopeptidase activity GO:0010951 84 0.011
purine nucleoside triphosphate metabolic process GO:0009144 412 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
purine nucleoside catabolic process GO:0006152 398 0.011
cell growth GO:0016049 160 0.011
purine ribonucleoside metabolic process GO:0046128 437 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
negative regulation of transferase activity GO:0051348 124 0.011
defense response GO:0006952 315 0.011
monocarboxylic acid biosynthetic process GO:0072330 67 0.011
positive regulation of locomotion GO:0040017 186 0.011
cellular response to endogenous stimulus GO:0071495 336 0.011
neuron projection regeneration GO:0031102 1 0.011
rhythmic behavior GO:0007622 2 0.011
purine nucleoside triphosphate catabolic process GO:0009146 392 0.011
regulation of cellular component biogenesis GO:0044087 281 0.011
positive regulation of hydrolase activity GO:0051345 331 0.011
nucleoside triphosphate metabolic process GO:0009141 422 0.011
microtubule organizing center organization GO:0031023 62 0.011
positive regulation of apoptotic signaling pathway GO:2001235 70 0.011
regulation of neurotransmitter secretion GO:0046928 3 0.011
endosomal transport GO:0016197 129 0.011
viral release from host cell GO:0019076 21 0.011
regulation of metal ion transport GO:0010959 120 0.011
regulation of transmembrane transport GO:0034762 139 0.011
organelle fission GO:0048285 149 0.011
negative regulation of immune system process GO:0002683 136 0.011
regulation of protein complex assembly GO:0043254 147 0.011
associative learning GO:0008306 1 0.011
response to topologically incorrect protein GO:0035966 29 0.011
protein destabilization GO:0031648 12 0.011
carboxylic acid biosynthetic process GO:0046394 97 0.011
cell adhesion GO:0007155 325 0.011
regulation of membrane potential GO:0042391 95 0.011
intracellular receptor signaling pathway GO:0030522 104 0.011
regulation of dna repair GO:0006282 47 0.011
rna catabolic process GO:0006401 71 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
cell type specific apoptotic process GO:0097285 125 0.010
protein modification by small protein removal GO:0070646 92 0.010
stem cell division GO:0017145 2 0.010
negative regulation of peptidase activity GO:0010466 91 0.010
actin filament organization GO:0007015 128 0.010
cellular response to extracellular stimulus GO:0031668 72 0.010
regulation of reactive oxygen species metabolic process GO:2000377 41 0.010
regulation of actin filament based process GO:0032970 141 0.010
cell cycle phase transition GO:0044770 173 0.010
spermatid development GO:0007286 4 0.010
viral entry into host cell GO:0046718 24 0.010
visual behavior GO:0007632 2 0.010
regulation of mapk cascade GO:0043408 262 0.010
developmental programmed cell death GO:0010623 3 0.010
positive regulation of transcription during mitosis GO:0045897 2 0.010
cellular response to external stimulus GO:0071496 111 0.010
ribonucleoside triphosphate metabolic process GO:0009199 412 0.010
oxidation reduction process GO:0055114 396 0.010
positive regulation of synaptic transmission GO:0050806 4 0.010

BFAR disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.035
nervous system disease DOID:863 431 0.035
musculoskeletal system disease DOID:17 223 0.027
retinal disease DOID:5679 118 0.026
eye and adnexa disease DOID:1492 150 0.026
eye disease DOID:5614 149 0.026
retinal degeneration DOID:8466 89 0.022
myopathy DOID:423 104 0.021
muscular disease DOID:0080000 114 0.021
muscle tissue disease DOID:66 113 0.021
immune system disease DOID:2914 155 0.020
retinitis pigmentosa DOID:10584 51 0.015
central nervous system disease DOID:331 186 0.013
bone disease DOID:0080001 88 0.013
connective tissue disease DOID:65 109 0.013
disease of mental health DOID:150 70 0.011
disease of metabolism DOID:0014667 295 0.011
inherited metabolic disorder DOID:655 242 0.011
muscular dystrophy DOID:9884 51 0.010
hematopoietic system disease DOID:74 100 0.010