|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
35 |
0.995
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.981
|
Mouse |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.980
|
Mouse |
|
|
positive regulation of release of cytochrome c from mitochondria
|
GO:0090200 |
18 |
0.980
|
|
|
|
regulation of release of cytochrome c from mitochondria
|
GO:0090199 |
29 |
0.977
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.972
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.971
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.964
|
|
|
|
regulation of protein oligomerization
|
GO:0032459 |
26 |
0.938
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.935
|
Mouse |
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
16 |
0.935
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.935
|
|
|
|
regulation of oxidative stress induced neuron death
|
GO:1903203 |
9 |
0.930
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.929
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.924
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.920
|
|
|
|
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
|
GO:1901030 |
3 |
0.916
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.904
|
Mouse |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.898
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
20 |
0.894
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.877
|
Mouse |
|
|
neuron death in response to oxidative stress
|
GO:0036475 |
9 |
0.869
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.865
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.857
|
Mouse |
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.856
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.852
|
Mouse |
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.845
|
Mouse |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.840
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
20 |
0.839
|
|
|
|
regulation of mitochondrial membrane permeability involved in apoptotic process
|
GO:1902108 |
18 |
0.834
|
Mouse |
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.831
|
Mouse |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.821
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
54 |
0.809
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.802
|
Mouse |
|
|
positive regulation of mitochondrion organization
|
GO:0010822 |
30 |
0.799
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.784
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
22 |
0.779
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.774
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
22 |
0.774
|
|
|
|
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway
|
GO:1903376 |
7 |
0.748
|
|
|
|
positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902177 |
4 |
0.739
|
|
|
|
neuron intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0036480 |
7 |
0.731
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.729
|
Mouse |
|
|
positive regulation of oxidative stress induced cell death
|
GO:1903209 |
5 |
0.726
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.719
|
Mouse |
|
|
t cell homeostasis
|
GO:0043029 |
3 |
0.704
|
|
|
|
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
|
GO:0001844 |
2 |
0.702
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.701
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.700
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.697
|
Mouse Rat |
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
8 |
0.683
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
31 |
0.681
|
|
|
|
positive regulation of protein oligomerization
|
GO:0032461 |
17 |
0.675
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.672
|
Mouse |
|
|
regulation of oxidative stress induced cell death
|
GO:1903201 |
24 |
0.668
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.668
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.654
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.645
|
Rat |
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.645
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.645
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.644
|
Mouse |
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
15 |
0.643
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.638
|
|
|
|
positive regulation of response to oxidative stress
|
GO:1902884 |
7 |
0.632
|
|
|
|
regulation of execution phase of apoptosis
|
GO:1900117 |
11 |
0.630
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.623
|
|
|
|
cellular response to increased oxygen levels
|
GO:0036295 |
4 |
0.606
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.604
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.591
|
|
|
|
positive regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway
|
GO:1903378 |
2 |
0.588
|
|
|
|
execution phase of apoptosis
|
GO:0097194 |
32 |
0.580
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.554
|
|
|
|
negative regulation of anoikis
|
GO:2000811 |
15 |
0.538
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.528
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.528
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.518
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.517
|
|
|
|
apoptotic process involved in morphogenesis
|
GO:0060561 |
3 |
0.508
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.502
|
|
|
|
regulation of membrane permeability
|
GO:0090559 |
25 |
0.500
|
Mouse |
|
|
regulation of apoptotic dna fragmentation
|
GO:1902510 |
3 |
0.477
|
|
|
|
mitochondrial membrane organization
|
GO:0007006 |
40 |
0.472
|
Mouse |
|
|
positive regulation of endoplasmic reticulum unfolded protein response
|
GO:1900103 |
4 |
0.470
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.464
|
|
|
|
regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902175 |
16 |
0.463
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.454
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
3 |
0.453
|
|
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
16 |
0.452
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.412
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.407
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.405
|
|
|
|
positive regulation of cellular response to oxidative stress
|
GO:1900409 |
7 |
0.395
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.394
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.385
|
Mouse |
|
|
regulation of mitochondrial membrane permeability
|
GO:0046902 |
25 |
0.373
|
Mouse |
|
|
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
|
GO:0070059 |
12 |
0.369
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.367
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
21 |
0.366
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.356
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.349
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.348
|
Rat |
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.344
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.336
|
Mouse |
|
|
positive regulation of protein homooligomerization
|
GO:0032464 |
7 |
0.332
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.330
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.327
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.325
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.319
|
|
|
|
positive regulation of execution phase of apoptosis
|
GO:1900119 |
5 |
0.311
|
|
|
|
mitochondrial fragmentation involved in apoptotic process
|
GO:0043653 |
7 |
0.304
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
25 |
0.300
|
|
|
|
regulation of fibroblast apoptotic process
|
GO:2000269 |
8 |
0.296
|
|
|
|
t cell apoptotic process
|
GO:0070231 |
12 |
0.293
|
|
|
|
negative regulation of lymphocyte apoptotic process
|
GO:0070229 |
8 |
0.292
|
|
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
26 |
0.291
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.285
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.283
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.282
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.278
|
|
|
|
transformed cell apoptotic process
|
GO:0006927 |
3 |
0.275
|
|
|
|
modulation by symbiont of host apoptotic process
|
GO:0052150 |
1 |
0.274
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.270
|
|
|
|
regulation of response to oxidative stress
|
GO:1902882 |
26 |
0.266
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.263
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.262
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.254
|
|
|
|
modulation of apoptotic process in other organism
|
GO:0044532 |
1 |
0.248
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.247
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.247
|
|
|
|
modulation of programmed cell death in other organism
|
GO:0044531 |
1 |
0.246
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.245
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.242
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.240
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.235
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.228
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.228
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.223
|
|
|
|
modulation by organism of apoptotic process in other organism involved in symbiotic interaction
|
GO:0052433 |
1 |
0.220
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.216
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.215
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.215
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.215
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.215
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.212
|
Mouse |
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.212
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.209
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.207
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.207
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.207
|
|
|
|
single organism membrane fusion
|
GO:0044801 |
37 |
0.207
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.202
|
Mouse |
|
|
necrotic cell death
|
GO:0070265 |
21 |
0.200
|
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
29 |
0.197
|
|
|
|
b cell apoptotic process
|
GO:0001783 |
6 |
0.196
|
|
|
|
modulation by symbiont of host programmed cell death
|
GO:0052040 |
1 |
0.194
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.194
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.193
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
14 |
0.193
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.190
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.186
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.186
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.184
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.184
|
|
|
|
modulation of programmed cell death in other organism involved in symbiotic interaction
|
GO:0052248 |
1 |
0.181
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.180
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.180
|
|
|
|
regulation of cellular ph reduction
|
GO:0032847 |
1 |
0.180
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.179
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.178
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.175
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.174
|
|
|
|
positive regulation of apoptotic process involved in morphogenesis
|
GO:1902339 |
1 |
0.172
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.170
|
|
|
|
behavioral defense response
|
GO:0002209 |
0 |
0.170
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.170
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.168
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.165
|
|
|
|
mitochondrial outer membrane permeabilization involved in programmed cell death
|
GO:1902686 |
16 |
0.165
|
Mouse |
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c
|
GO:0008635 |
2 |
0.164
|
|
|
|
modulation by symbiont of host cellular process
|
GO:0044068 |
3 |
0.163
|
|
|
|
regulation of anoikis
|
GO:2000209 |
19 |
0.162
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.161
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.161
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.159
|
|
|
|
negative regulation of mitochondrion organization
|
GO:0010823 |
22 |
0.158
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.158
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.158
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.156
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.155
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.155
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.152
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
18 |
0.148
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.147
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.147
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.146
|
|
|
|
positive regulation of apoptotic process involved in mammary gland involution
|
GO:0060058 |
1 |
0.143
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.143
|
|
|
|
mitochondrial transport
|
GO:0006839 |
60 |
0.142
|
Mouse |
|
|
cellular response to hyperoxia
|
GO:0071455 |
4 |
0.141
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.141
|
|
|
|
fear response
|
GO:0042596 |
0 |
0.139
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.138
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.138
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.138
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.137
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.137
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.136
|
Mouse |
|
|
mitochondrial outer membrane permeabilization
|
GO:0097345 |
15 |
0.135
|
Mouse |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.134
|
Mouse |
|
|
regulation of b cell apoptotic process
|
GO:0002902 |
5 |
0.133
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.133
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.132
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.131
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
40 |
0.131
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.131
|
|
|
|
positive regulation of mitochondrial membrane permeability
|
GO:0035794 |
17 |
0.130
|
Mouse |
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.129
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.129
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.129
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.129
|
|
|
|
protein insertion into mitochondrial membrane
|
GO:0051204 |
3 |
0.125
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.124
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.124
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.124
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.122
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.122
|
|
|
|
regulation of endoplasmic reticulum unfolded protein response
|
GO:1900101 |
5 |
0.118
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.118
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.117
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.116
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.116
|
|
|
|
positive regulation of skeletal muscle tissue development
|
GO:0048643 |
1 |
0.114
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.113
|
|
|
|
regulation of developmental pigmentation
|
GO:0048070 |
2 |
0.113
|
|
|
|
response to hyperoxia
|
GO:0055093 |
4 |
0.112
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.112
|
|
|
|
modulation by virus of host morphology or physiology
|
GO:0019048 |
10 |
0.112
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
23 |
0.111
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.111
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.110
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
4 |
0.106
|
|
|
|
membrane fusion
|
GO:0061025 |
43 |
0.106
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.106
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.105
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.105
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.104
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.104
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.104
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.103
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.103
|
|
|
|
negative regulation of signal transduction in absence of ligand
|
GO:1901099 |
16 |
0.102
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.101
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.101
|
|
|
|
modulation by virus of host process
|
GO:0019054 |
2 |
0.101
|
|
|
|
response to increased oxygen levels
|
GO:0036296 |
4 |
0.097
|
|
|
|
regulation of protein heterodimerization activity
|
GO:0043497 |
5 |
0.096
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.095
|
Rat |
|
|
epithelium development
|
GO:0060429 |
227 |
0.094
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.094
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.093
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.093
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.092
|
Mouse |
|
|
b cell homeostasis
|
GO:0001782 |
1 |
0.091
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.091
|
|
|
|
negative regulation of calcium ion transport into cytosol
|
GO:0010523 |
3 |
0.091
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.091
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.090
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.090
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
7 |
0.090
|
|
|
|
thymus development
|
GO:0048538 |
3 |
0.089
|
|
|
|
organelle fusion
|
GO:0048284 |
36 |
0.089
|
|
|
|
organic anion transport
|
GO:0015711 |
103 |
0.087
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
1 |
0.087
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.087
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.087
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.086
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.086
|
|
|
|
regulation of apoptotic process involved in morphogenesis
|
GO:1902337 |
1 |
0.086
|
|
|
|
regulation of protein homooligomerization
|
GO:0032462 |
11 |
0.085
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.085
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.083
|
|
|
|
positive regulation of fibroblast apoptotic process
|
GO:2000271 |
6 |
0.081
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.081
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.080
|
Mouse |
|
|
regulation of cell killing
|
GO:0031341 |
22 |
0.080
|
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.079
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.078
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.078
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.078
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.078
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.077
|
|
|
|
regulation of mitochondrial fusion
|
GO:0010635 |
5 |
0.077
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.077
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.075
|
|
|
|
trail activated apoptotic signaling pathway
|
GO:0036462 |
4 |
0.075
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.074
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.074
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.072
|
|
|
|
positive regulation of mitochondrial membrane permeability involved in apoptotic process
|
GO:1902110 |
16 |
0.072
|
Mouse |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.072
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.071
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.071
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.071
|
|
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.070
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.070
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.070
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.069
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.068
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.068
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001241 |
4 |
0.068
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.068
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.067
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.067
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.067
|
Rat |
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.067
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.063
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.062
|
|
|
|
mitochondrial fusion
|
GO:0008053 |
13 |
0.062
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.061
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.061
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
0.061
|
|
|
|
negative regulation of protein binding
|
GO:0032091 |
35 |
0.061
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.061
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.060
|
|
|
|
response to cobalt ion
|
GO:0032025 |
1 |
0.060
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.058
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.058
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.058
|
|
|
|
regulation of mitochondrial membrane potential
|
GO:0051881 |
23 |
0.058
|
|
|
|
spleen development
|
GO:0048536 |
1 |
0.058
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.058
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.057
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.057
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.057
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.057
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.055
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.055
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.055
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.054
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.054
|
|
|
|
positive regulation of dna catabolic process
|
GO:1903626 |
2 |
0.054
|
|
|
|
dna catabolic process endonucleolytic
|
GO:0000737 |
37 |
0.054
|
|
|
|
positive regulation of developmental pigmentation
|
GO:0048087 |
2 |
0.053
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.053
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.052
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.052
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.051
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
43 |
0.051
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.051
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
17 |
0.050
|
|
|
|
regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902041 |
24 |
0.050
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.050
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.049
|
|
|
|
modification by symbiont of host morphology or physiology
|
GO:0044003 |
12 |
0.049
|
|
|
|
t cell selection
|
GO:0045058 |
4 |
0.049
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
24 |
0.049
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.048
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.048
|
|
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.048
|
|
|
|
regulation of killing of cells of other organism
|
GO:0051709 |
4 |
0.048
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.048
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.048
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.048
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.048
|
|
|
|
positive regulation of oxidative stress induced neuron death
|
GO:1903223 |
2 |
0.048
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.048
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.047
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.047
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.046
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.046
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.046
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.046
|
|
|
|
positive regulation of killing of cells of other organism
|
GO:0051712 |
4 |
0.046
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.045
|
|
|
|
neural tube development
|
GO:0021915 |
9 |
0.045
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.045
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.045
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.044
|
|
|
|
regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
|
GO:1901028 |
9 |
0.044
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.044
|
Rat |
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.044
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.044
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.044
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.044
|
|
|
|
negative regulation of execution phase of apoptosis
|
GO:1900118 |
6 |
0.044
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.044
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.043
|
|
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.043
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.043
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.042
|
Rat |
|
|
protein targeting
|
GO:0006605 |
187 |
0.042
|
Mouse |
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.042
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.042
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.042
|
|
|
|
mating
|
GO:0007618 |
1 |
0.042
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.042
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.041
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.041
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.041
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001267 |
2 |
0.041
|
|
|
|
apoptotic dna fragmentation
|
GO:0006309 |
6 |
0.041
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.041
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.041
|
|
|
|
response to toxic substance
|
GO:0009636 |
37 |
0.040
|
|
|
|
negative regulation by symbiont of host apoptotic process
|
GO:0033668 |
1 |
0.040
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.040
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
33 |
0.040
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.040
|
Mouse |
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.040
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.039
|
|
|
|
cellular component disassembly involved in execution phase of apoptosis
|
GO:0006921 |
13 |
0.039
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.039
|
|
|
|
hypothalamus development
|
GO:0021854 |
1 |
0.039
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.038
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.038
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.038
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.038
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.038
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001269 |
1 |
0.037
|
|
|
|
anoikis
|
GO:0043276 |
22 |
0.037
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.037
|
Mouse |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.037
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.037
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.036
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.035
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.035
|
|
|
|
positive regulation of apoptotic dna fragmentation
|
GO:1902512 |
1 |
0.035
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.035
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.035
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.035
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.034
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.034
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.034
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.034
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.034
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.034
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.033
|
|
|
|
centrosome duplication
|
GO:0051298 |
28 |
0.033
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.033
|
|
|
|
patterning of blood vessels
|
GO:0001569 |
2 |
0.033
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.033
|
|
|
|
negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction
|
GO:0052490 |
1 |
0.033
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.033
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.033
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.032
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.032
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.032
|
Mouse |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.032
|
|
|
|
modification of morphology or physiology of other organism involved in symbiotic interaction
|
GO:0051817 |
38 |
0.032
|
|
|
|
activation induced cell death of t cells
|
GO:0006924 |
2 |
0.032
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.032
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.031
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.031
|
|
|
|
release of matrix enzymes from mitochondria
|
GO:0032976 |
1 |
0.030
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.030
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.030
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.030
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.030
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.030
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.030
|
|
|
|
positive regulation of calcium ion transport into cytosol
|
GO:0010524 |
20 |
0.030
|
|
|
|
growth
|
GO:0040007 |
202 |
0.030
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.029
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
23 |
0.029
|
|
|
|
thymic t cell selection
|
GO:0045061 |
2 |
0.029
|
|
|
|
mitochondrial fission
|
GO:0000266 |
14 |
0.029
|
|
|
|
modulation by virus of host apoptotic process
|
GO:0039526 |
1 |
0.029
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.029
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.029
|
Mouse |
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.029
|
|
|
|
response to transition metal nanoparticle
|
GO:1990267 |
29 |
0.029
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.029
|
Mouse |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.029
|
|
|
|
establishment or maintenance of transmembrane electrochemical gradient
|
GO:0010248 |
2 |
0.029
|
|
|
|
centrosome cycle
|
GO:0007098 |
32 |
0.028
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.028
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.028
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.028
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.028
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.028
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.027
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.027
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.027
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.027
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.027
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.027
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.027
|
|
