Homo sapiens

163 known processes

BIRC5

baculoviral IAP repeat containing 5

(Aliases: API4,EPR-1)

BIRC5 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of microtubule based process GO:0032886 74 0.966
histone serine phosphorylation GO:0035404 4 0.852
microtubule cytoskeleton organization GO:0000226 176 0.851
Mouse
negative regulation of microtubule polymerization or depolymerization GO:0031111 17 0.833
spindle midzone assembly GO:0051255 4 0.832
regulation of microtubule cytoskeleton organization GO:0070507 61 0.818
microtubule polymerization or depolymerization GO:0031109 37 0.815
sister chromatid segregation GO:0000819 54 0.814
spindle assembly GO:0051225 29 0.801
protein depolymerization GO:0051261 30 0.594
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.580
regulation of cell cycle GO:0051726 393 0.571
negative regulation of apoptotic process GO:0043066 316 0.539
positive regulation of cell cycle GO:0045787 140 0.492
spindle assembly involved in mitosis GO:0090307 12 0.462
spindle organization GO:0007051 53 0.459
chromatin modification GO:0016568 298 0.439
covalent chromatin modification GO:0016569 254 0.412
positive regulation of cell cycle process GO:0090068 106 0.379
negative regulation of cytoskeleton organization GO:0051494 45 0.358
centrosome organization GO:0051297 58 0.353
mitotic cell cycle GO:0000278 326 0.350
protein complex disassembly GO:0043241 52 0.349
chromosome segregation GO:0007059 114 0.349
regulation of chromosome segregation GO:0051983 44 0.331
microtubule depolymerization GO:0007019 18 0.326
regulation of spindle organization GO:0090224 10 0.326
microtubule based process GO:0007017 210 0.323
Mouse
centrosome separation GO:0051299 3 0.318
circulatory system development GO:0072359 262 0.311
mitotic nuclear division GO:0007067 119 0.305
organelle assembly GO:0070925 176 0.294
histone phosphorylation GO:0016572 16 0.288
negative regulation of protein depolymerization GO:1901880 17 0.284
chromatin organization GO:0006325 351 0.262
histone modification GO:0016570 251 0.252
cell division GO:0051301 168 0.214
organelle fission GO:0048285 149 0.212
spindle stabilization GO:0043146 4 0.206
negative regulation of organelle organization GO:0010639 126 0.197
cellular protein complex disassembly GO:0043624 36 0.195
mitotic sister chromatid segregation GO:0000070 53 0.193
peptidyl serine phosphorylation GO:0018105 101 0.192
centrosome duplication GO:0051298 28 0.191
negative regulation of cellular protein metabolic process GO:0032269 353 0.176
mitotic spindle elongation GO:0000022 4 0.172
single organism cellular localization GO:1902580 332 0.172
regulation of protein depolymerization GO:1901879 22 0.164
immune system development GO:0002520 195 0.161
regulation of mitotic sister chromatid segregation GO:0033047 27 0.153
negative regulation of phosphorus metabolic process GO:0010563 267 0.152
response to hormone GO:0009725 175 0.146
negative regulation of cell cycle process GO:0010948 121 0.138
cell type specific apoptotic process GO:0097285 125 0.136
Mouse
regulation of protein complex assembly GO:0043254 147 0.129
dna repair GO:0006281 198 0.127
mitotic cell cycle process GO:1903047 286 0.123
cell cycle g2 m phase transition GO:0044839 43 0.123
dephosphorylation GO:0016311 209 0.122
negative regulation of phosphate metabolic process GO:0045936 267 0.119
protein dephosphorylation GO:0006470 81 0.117
mitotic centrosome separation GO:0007100 1 0.115
mitotic sister chromatid separation GO:0051306 18 0.111
cellular response to uv GO:0034644 32 0.110
cell fate determination GO:0001709 3 0.110
positive regulation of catabolic process GO:0009896 310 0.110
positive regulation of cellular component organization GO:0051130 376 0.108
cellular component disassembly GO:0022411 92 0.102
regulation of cytoskeleton organization GO:0051493 177 0.101
spindle elongation GO:0051231 4 0.101
mitotic spindle midzone assembly GO:0051256 4 0.099
regulation of cell cycle process GO:0010564 266 0.096
negative regulation of protein metabolic process GO:0051248 391 0.096
response to abiotic stimulus GO:0009628 336 0.095
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.095
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.093
post embryonic development GO:0009791 2 0.092
regulation of cell growth GO:0001558 135 0.091
regulation of mitosis GO:0007088 63 0.089
cellular response to endogenous stimulus GO:0071495 336 0.089
mitotic cytokinesis GO:0000281 19 0.089
negative regulation of protein maturation GO:1903318 142 0.088
nucleocytoplasmic transport GO:0006913 176 0.086
cytokinesis GO:0000910 96 0.082
negative regulation of cellular component organization GO:0051129 235 0.081
positive regulation of exit from mitosis GO:0031536 2 0.080
negative regulation of proteolysis GO:0045861 132 0.080
mitotic spindle organization GO:0007052 27 0.079
nuclear division GO:0000280 128 0.077
regulation of kinase activity GO:0043549 314 0.076
intracellular protein transport GO:0006886 270 0.074
response to radiation GO:0009314 151 0.071
positive regulation of cytokinesis GO:0032467 29 0.069
negative regulation of b cell apoptotic process GO:0002903 4 0.067
negative regulation of protein processing GO:0010955 142 0.066
negative regulation of phosphorylation GO:0042326 174 0.065
cellular response to dna damage stimulus GO:0006974 379 0.065
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.060
cyclin catabolic process GO:0008054 6 0.060
protein catabolic process GO:0030163 325 0.059
protein localization to chromosome GO:0034502 30 0.059
protein processing GO:0016485 226 0.058
organelle localization GO:0051640 84 0.055
immune response GO:0006955 307 0.055
regulation of cytokinesis GO:0032465 45 0.055
negative regulation of catalytic activity GO:0043086 335 0.054
organophosphate catabolic process GO:0046434 430 0.054
response to oxidative stress GO:0006979 121 0.052
regulation of protein processing GO:0070613 150 0.051
regulation of cell division GO:0051302 116 0.051
regulation of proteolysis GO:0030162 293 0.050
cellular response to radiation GO:0071478 65 0.048
meiotic nuclear division GO:0007126 10 0.047
ubiquitin dependent protein catabolic process GO:0006511 206 0.046
erythrocyte homeostasis GO:0034101 31 0.046
negative regulation of cell death GO:0060548 345 0.045
multicellular organismal aging GO:0010259 3 0.045
regulation of protein kinase activity GO:0045859 289 0.045
actin cytoskeleton organization GO:0030036 207 0.044
cellular amine metabolic process GO:0044106 41 0.044
modification dependent macromolecule catabolic process GO:0043632 212 0.043
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.043
golgi inheritance GO:0048313 2 0.043
response to uv GO:0009411 73 0.041
regulation of protein localization GO:0032880 296 0.041
cellular response to abiotic stimulus GO:0071214 117 0.040
response to light stimulus GO:0009416 87 0.040
microtubule cytoskeleton organization involved in mitosis GO:1902850 15 0.040
regulation of proteasomal protein catabolic process GO:0061136 87 0.040
positive regulation of transferase activity GO:0051347 227 0.039
purine nucleoside triphosphate catabolic process GO:0009146 392 0.039
metaphase plate congression GO:0051310 18 0.039
regulation of transferase activity GO:0051338 355 0.039
actin filament based process GO:0030029 224 0.038
heart development GO:0007507 95 0.038
response to biotic stimulus GO:0009607 276 0.038
lymphocyte apoptotic process GO:0070227 20 0.038
regulation of myeloid cell differentiation GO:0045637 81 0.038
establishment of chromosome localization GO:0051303 20 0.036
negative regulation of hydrolase activity GO:0051346 182 0.036
cellular macromolecular complex assembly GO:0034622 324 0.036
regulation of cellular response to stress GO:0080135 244 0.036
peptidyl serine modification GO:0018209 106 0.036
cell part morphogenesis GO:0032990 137 0.035
metaphase anaphase transition of cell cycle GO:0044784 21 0.035
protein localization to organelle GO:0033365 280 0.034
negative regulation of developmental process GO:0051093 247 0.033
regulation of lymphocyte apoptotic process GO:0070228 15 0.033
response to external biotic stimulus GO:0043207 261 0.033
positive regulation of phosphorylation GO:0042327 394 0.033
endocytosis GO:0006897 159 0.032
myeloid cell differentiation GO:0030099 117 0.032
vesicle mediated transport GO:0016192 371 0.032
establishment of ribosome localization GO:0033753 4 0.031
ras protein signal transduction GO:0007265 73 0.031
oocyte differentiation GO:0009994 2 0.031
positive regulation of developmental process GO:0051094 314 0.031
establishment of cell polarity GO:0030010 22 0.031
protein autophosphorylation GO:0046777 123 0.030
negative regulation of programmed cell death GO:0043069 321 0.030
oocyte maturation GO:0001556 1 0.029
response to decreased oxygen levels GO:0036293 96 0.029
negative regulation of protein complex disassembly GO:0043242 20 0.029
cell cycle arrest GO:0007050 71 0.029
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.029
positive regulation of proteolysis GO:0045862 142 0.028
cytoplasmic transport GO:0016482 379 0.028
cellular amino acid metabolic process GO:0006520 116 0.028
microtubule organizing center organization GO:0031023 62 0.028
regulation of protein catabolic process GO:0042176 155 0.028
purine nucleoside triphosphate metabolic process GO:0009144 412 0.028
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.027
nervous system development GO:0007399 293 0.027
ribonucleoside catabolic process GO:0042454 406 0.027
regulation of protein binding GO:0043393 66 0.027
positive regulation of protein phosphorylation GO:0001934 313 0.027
negative regulation of peptidase activity GO:0010466 91 0.027
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.026
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.026
macromolecular complex disassembly GO:0032984 60 0.026
centrosome cycle GO:0007098 32 0.026
regulation of cell differentiation GO:0045595 393 0.025
positive regulation of protein kinase activity GO:0045860 190 0.025
cellular macromolecule catabolic process GO:0044265 380 0.025
determination of adult lifespan GO:0008340 2 0.025
regulation of protein serine threonine kinase activity GO:0071900 179 0.025
negative regulation of protein modification process GO:0031400 200 0.025
negative regulation of cell cycle GO:0045786 193 0.024
cytoskeleton dependent cytokinesis GO:0061640 22 0.024
positive regulation of immune system process GO:0002684 283 0.024
mitotic metaphase plate congression GO:0007080 14 0.024
regulation of binding GO:0051098 111 0.024
establishment of organelle localization GO:0051656 59 0.023
intrinsic apoptotic signaling pathway GO:0097193 127 0.023
regulation of dephosphorylation GO:0035303 96 0.023
ribonucleoside triphosphate metabolic process GO:0009199 412 0.023
cell aging GO:0007569 52 0.022
mitotic cell cycle phase transition GO:0044772 162 0.022
regulation of cytoplasmic transport GO:1903649 149 0.022
cell cycle g1 s phase transition GO:0044843 80 0.022
mitotic chromosome condensation GO:0007076 11 0.021
regulation of cellular amino acid metabolic process GO:0006521 6 0.021
deoxyribose phosphate metabolic process GO:0019692 6 0.021
negative regulation of microtubule depolymerization GO:0007026 12 0.021
negative regulation of protein phosphorylation GO:0001933 140 0.021
small gtpase mediated signal transduction GO:0007264 78 0.021
g2 m transition of mitotic cell cycle GO:0000086 41 0.020
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.020
negative regulation of cellular catabolic process GO:0031330 83 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.020
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.020
establishment of spindle localization GO:0051293 12 0.020
regulation of intracellular transport GO:0032386 195 0.020
striated muscle myosin thick filament assembly GO:0071688 2 0.020
receptor mediated endocytosis GO:0006898 84 0.020
regulation of meiotic cell cycle GO:0051445 4 0.020
response to oxygen levels GO:0070482 100 0.019
leukocyte apoptotic process GO:0071887 31 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
regulation of immune response GO:0050776 201 0.019
positive regulation of cellular catabolic process GO:0031331 284 0.019
purine ribonucleoside catabolic process GO:0046130 398 0.019
regulation of chromosome organization GO:0033044 103 0.019
embryo development GO:0009790 123 0.019
Mouse
neuron projection development GO:0031175 106 0.018
regulation of nuclear division GO:0051783 65 0.018
nucleoside phosphate catabolic process GO:1901292 412 0.018
cellular response to hypoxia GO:0071456 51 0.018
regulation of cellular amine metabolic process GO:0033238 11 0.018
regulation of attachment of spindle microtubules to kinetochore GO:0051988 9 0.018
cellular protein catabolic process GO:0044257 261 0.017
cell growth GO:0016049 160 0.017
gtp metabolic process GO:0046039 239 0.017
regulation of endopeptidase activity GO:0052548 170 0.017
negative regulation of cell size GO:0045792 3 0.017
reproduction GO:0000003 63 0.017
myosin filament organization GO:0031033 2 0.016
regulation of centrosome cycle GO:0046605 15 0.016
positive regulation of cell division GO:0051781 59 0.016
regulation of mitotic sister chromatid separation GO:0010965 27 0.016
dna conformation change GO:0071103 113 0.016
erythrocyte differentiation GO:0030218 28 0.016
hematopoietic or lymphoid organ development GO:0048534 186 0.016
positive regulation of dna metabolic process GO:0051054 73 0.016
signal transduction by phosphorylation GO:0023014 297 0.015
ribosome assembly GO:0042255 9 0.015
ribonucleoprotein complex localization GO:0071166 4 0.015
protein maturation GO:0051604 233 0.015
nuclear transport GO:0051169 179 0.015
establishment of protein localization to organelle GO:0072594 172 0.015
cell morphogenesis GO:0000902 296 0.015
neurogenesis GO:0022008 169 0.015
nucleotide biosynthetic process GO:0009165 109 0.015
regulation of cellular ketone metabolic process GO:0010565 50 0.015
cellular component morphogenesis GO:0032989 314 0.015
negative regulation of immune system process GO:0002683 136 0.014
regulation of microtubule depolymerization GO:0031114 12 0.014
regulation of protein maturation GO:1903317 150 0.014
dna packaging GO:0006323 77 0.014
protein localization to nucleus GO:0034504 136 0.014
regulation of peptidase activity GO:0052547 180 0.014
cellular protein complex assembly GO:0043623 188 0.014
tissue regeneration GO:0042246 3 0.014
regulation of mitotic cell cycle GO:0007346 189 0.014
negative regulation of dephosphorylation GO:0035305 63 0.014
positive regulation of mitosis GO:0045840 25 0.014
negative regulation of cell cycle phase transition GO:1901988 89 0.014
nucleotide catabolic process GO:0009166 408 0.014
regulation of cell cycle g1 s phase transition GO:1902806 42 0.014
negative regulation of cell growth GO:0030308 83 0.013
regulation of anatomical structure size GO:0090066 101 0.013
organophosphate biosynthetic process GO:0090407 163 0.013
regeneration GO:0031099 4 0.013
rna interference GO:0016246 4 0.013
regulation of phosphatase activity GO:0010921 81 0.013
regulation of reactive oxygen species metabolic process GO:2000377 41 0.013
oxidation reduction process GO:0055114 396 0.013
protein targeting GO:0006605 187 0.013
response to hypoxia GO:0001666 96 0.013
lymphocyte activation GO:0046649 133 0.012
regulation of small gtpase mediated signal transduction GO:0051056 156 0.012
amine metabolic process GO:0009308 44 0.012
regulation of establishment of protein localization GO:0070201 242 0.012
regulation of purine nucleotide metabolic process GO:1900542 264 0.012
protein import into nucleus GO:0006606 104 0.012
spermatid differentiation GO:0048515 4 0.012
reactive oxygen species metabolic process GO:0072593 75 0.012
biological adhesion GO:0022610 331 0.012
attachment of spindle microtubules to kinetochore GO:0008608 17 0.012
response to organic cyclic compound GO:0014070 204 0.012
cellular lipid metabolic process GO:0044255 303 0.012
cellular response to hormone stimulus GO:0032870 125 0.012
cellular response to oxygen levels GO:0071453 55 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
negative regulation of transport GO:0051051 176 0.012
dna biosynthetic process GO:0071897 40 0.012
meiosis i GO:0007127 4 0.011
homeostasis of number of cells GO:0048872 40 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
regulation of lymphocyte activation GO:0051249 103 0.011
regulation of mapk cascade GO:0043408 262 0.011
regulation of ras protein signal transduction GO:0046578 155 0.011
defense response GO:0006952 315 0.011
regulation of protein dephosphorylation GO:0035304 18 0.011
protein targeting to nucleus GO:0044744 104 0.011
mapk cascade GO:0000165 288 0.011
spindle checkpoint GO:0031577 26 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
regulation of nervous system development GO:0051960 88 0.011
regulation of cell activation GO:0050865 125 0.011
female gamete generation GO:0007292 2 0.011
positive regulation of cellular amine metabolic process GO:0033240 7 0.011
regulation of intracellular protein transport GO:0033157 123 0.011
negative regulation of protein kinase activity GO:0006469 98 0.010
myosin filament assembly GO:0031034 2 0.010
neuromuscular junction development GO:0007528 3 0.010
protein homooligomerization GO:0051260 100 0.010
positive regulation of hydrolase activity GO:0051345 331 0.010
cellular response to light stimulus GO:0071482 34 0.010
cell fate commitment GO:0045165 27 0.010

BIRC5 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.013
cancer DOID:162 167 0.013