Homo sapiens

32 known processes

BLNK

B-cell linker

(Aliases: BLNK-S,SLP65,SLP-65,AGM4,LY57,BASH,MGC111051)

BLNK biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
azole transport GO:0045117 4 0.999
mast cell degranulation GO:0043303 4 0.931
immune response activating signal transduction GO:0002757 90 0.890
caveolin mediated endocytosis GO:0072584 4 0.881
cation transport GO:0006812 331 0.864
positive regulation of mast cell activation GO:0033005 2 0.852
regulation of hormone levels GO:0010817 125 0.831
cell activation GO:0001775 213 0.819
regulation of cellular amine metabolic process GO:0033238 11 0.819
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.813
activation of immune response GO:0002253 114 0.790
mast cell activation involved in immune response GO:0002279 4 0.770
regulation of cytokine production GO:0001817 232 0.750
enzyme linked receptor protein signaling pathway GO:0007167 303 0.746
cellular ketone metabolic process GO:0042180 80 0.720
regulation of transferase activity GO:0051338 355 0.714
leukocyte activation GO:0045321 164 0.704
regulation of secretion GO:0051046 194 0.695
positive regulation of exocytosis GO:0045921 35 0.690
immune response regulating signaling pathway GO:0002764 97 0.689
positive regulation of jnk cascade GO:0046330 52 0.685
positive regulation of interferon gamma mediated signaling pathway GO:0060335 2 0.684
negative regulation of sequestering of calcium ion GO:0051283 41 0.663
cellular amine metabolic process GO:0044106 41 0.661
positive regulation of transport GO:0051050 336 0.659
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.646
t cell receptor signaling pathway GO:0050852 21 0.645
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.624
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.610
inflammatory response GO:0006954 79 0.600
cellular lipid metabolic process GO:0044255 303 0.598
regulation of icosanoid secretion GO:0032303 4 0.597
endosomal transport GO:0016197 129 0.595
positive regulation of immune system process GO:0002684 283 0.591
amine metabolic process GO:0009308 44 0.584
antigen receptor mediated signaling pathway GO:0050851 38 0.577
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.569
cellular response to growth factor stimulus GO:0071363 197 0.553
regulation of receptor mediated endocytosis GO:0048259 32 0.551
regulation of platelet aggregation GO:0090330 4 0.536
peptidyl tyrosine phosphorylation GO:0018108 170 0.536
regulation of cell adhesion GO:0030155 166 0.526
regulation of protein oligomerization GO:0032459 26 0.525
cellular response to endogenous stimulus GO:0071495 336 0.519
regulation of blood coagulation GO:0030193 42 0.517
serotonin transport GO:0006837 3 0.512
vesicle mediated transport GO:0016192 371 0.495
cellular chemical homeostasis GO:0055082 180 0.495
cellular amino acid metabolic process GO:0006520 116 0.492
lipid metabolic process GO:0006629 381 0.490
exocytosis GO:0006887 71 0.489
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.486
negative regulation of homeostatic process GO:0032845 59 0.482
myeloid leukocyte activation GO:0002274 34 0.482
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.478
regulation of leukocyte activation GO:0002694 115 0.474
regulation of mast cell activation involved in immune response GO:0033006 3 0.456
actin filament organization GO:0007015 128 0.448
regulation of cellular ketone metabolic process GO:0010565 50 0.447
sequestering of calcium ion GO:0051208 17 0.424
peptidyl tyrosine modification GO:0018212 170 0.416
positive regulation of kinase activity GO:0033674 204 0.414
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.411
determination of adult lifespan GO:0008340 2 0.407
regulation of immune response GO:0050776 201 0.399
regulation of cellular amino acid metabolic process GO:0006521 6 0.389
inositol lipid mediated signaling GO:0048017 55 0.386
cation homeostasis GO:0055080 189 0.384
cellular ion homeostasis GO:0006873 168 0.371
positive regulation of leukocyte activation GO:0002696 80 0.370
positive regulation of cytokine production GO:0001819 167 0.370
myeloid cell activation involved in immune response GO:0002275 10 0.369
multicellular organismal aging GO:0010259 3 0.368
immune effector process GO:0002252 159 0.367
purine nucleotide catabolic process GO:0006195 405 0.362
immune system development GO:0002520 195 0.361
integrin mediated signaling pathway GO:0007229 32 0.361
nitrogen compound transport GO:0071705 191 0.352
chemical homeostasis GO:0048878 306 0.350
secretion GO:0046903 254 0.349
cytoplasmic transport GO:0016482 379 0.348
negative regulation of cell death GO:0060548 345 0.344
regulation of protein kinase activity GO:0045859 289 0.344
cytokine production GO:0001816 247 0.341
regulation of cellular component biogenesis GO:0044087 281 0.340
regulation of jnk cascade GO:0046328 73 0.337
regulation of stress activated mapk cascade GO:0032872 84 0.334
cell activation involved in immune response GO:0002263 30 0.334
actin filament polymerization GO:0030041 45 0.331
lymphocyte activation GO:0046649 133 0.329
phospholipid metabolic process GO:0006644 99 0.324
positive regulation of immune response GO:0050778 159 0.323
negative regulation of cellular amine metabolic process GO:0033239 3 0.321
regulation of ion homeostasis GO:2000021 73 0.315
positive regulation of secretion by cell GO:1903532 108 0.315
immune response GO:0006955 307 0.309
regulation of cell cell adhesion GO:0022407 57 0.307
positive regulation of interferon gamma production GO:0032729 26 0.306
regulation of cell activation GO:0050865 125 0.306
coagulation GO:0050817 78 0.305
mononuclear cell proliferation GO:0032943 71 0.304
regulation of defense response GO:0031347 154 0.302
guanosine containing compound catabolic process GO:1901069 239 0.302
organ morphogenesis GO:0009887 147 0.296
serotonin secretion GO:0001820 1 0.294
leukocyte activation involved in immune response GO:0002366 30 0.289
gtp metabolic process GO:0046039 239 0.288
positive regulation of granulocyte macrophage colony stimulating factor production GO:0032725 4 0.286
regulation of kinase activity GO:0043549 314 0.282
menstrual cycle phase GO:0022601 2 0.280
response to oxygen containing compound GO:1901700 369 0.275
leukocyte proliferation GO:0070661 74 0.270
female gamete generation GO:0007292 2 0.267
positive regulation of cellular component organization GO:0051130 376 0.267
response to fungus GO:0009620 4 0.266
protein processing GO:0016485 226 0.266
early endosome to late endosome transport GO:0045022 21 0.263
regulation of peptidase activity GO:0052547 180 0.257
stress activated protein kinase signaling cascade GO:0031098 94 0.256
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.255
regulation of secretion by cell GO:1903530 177 0.251
mast cell mediated immunity GO:0002448 5 0.251
regulation of intracellular transport GO:0032386 195 0.249
divalent metal ion transport GO:0070838 152 0.244
peptide secretion GO:0002790 51 0.240
regulation of mast cell activation GO:0033003 5 0.236
positive regulation of stress activated mapk cascade GO:0032874 60 0.236
positive regulation of leukocyte degranulation GO:0043302 3 0.236
regulation of mapk cascade GO:0043408 262 0.234
regulation of lymphocyte proliferation GO:0050670 64 0.232
stress activated mapk cascade GO:0051403 93 0.229
negative regulation of protein oligomerization GO:0032460 8 0.227
response to growth factor GO:0070848 205 0.225
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.224
regulation of mononuclear cell proliferation GO:0032944 65 0.223
positive regulation of secretion GO:0051047 116 0.223
negative regulation of transforming growth factor beta1 production GO:0032911 2 0.222
signal release GO:0023061 70 0.221
positive regulation of phosphorylation GO:0042327 394 0.221
intrinsic apoptotic signaling pathway GO:0097193 127 0.219
leukocyte mediated immunity GO:0002443 59 0.219
regulation of cell differentiation GO:0045595 393 0.218
positive regulation of t cell activation GO:0050870 54 0.217
defense response GO:0006952 315 0.214
regulation of actin polymerization or depolymerization GO:0008064 56 0.214
regulated secretory pathway GO:0045055 20 0.211
response to lipid GO:0033993 206 0.211
epithelium migration GO:0090132 119 0.210
positive regulation of lipid metabolic process GO:0045834 50 0.209
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.204
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.203
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.203
positive regulation of protein kinase b signaling GO:0051897 42 0.202
cellular divalent inorganic cation homeostasis GO:0072503 128 0.200
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.199
regulation of lipid kinase activity GO:0043550 19 0.198
regulation of cytoskeleton organization GO:0051493 177 0.193
regulation of insulin secretion GO:0050796 33 0.193
regulation of cell projection organization GO:0031344 107 0.191
innate immune response GO:0045087 178 0.191
negative regulation of programmed cell death GO:0043069 321 0.191
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 28 0.190
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.189
regulation of lymphocyte activation GO:0051249 103 0.188
regulation of podosome assembly GO:0071801 5 0.187
regulation of mitochondrial membrane potential GO:0051881 23 0.185
positive regulation of response to interferon gamma GO:0060332 2 0.183
response to interleukin 1 GO:0070555 47 0.183
jnk cascade GO:0007254 80 0.183
regulation of vesicle mediated transport GO:0060627 130 0.183
anatomical structure formation involved in morphogenesis GO:0048646 284 0.182
salivary gland morphogenesis GO:0007435 4 0.181
positive regulation of map kinase activity GO:0043406 80 0.180
endocytosis GO:0006897 159 0.180
neutrophil activation involved in immune response GO:0002283 3 0.179
positive regulation of myeloid leukocyte mediated immunity GO:0002888 1 0.177
negative regulation of protein metabolic process GO:0051248 391 0.176
protein oligomerization GO:0051259 173 0.176
positive regulation of regulated secretory pathway GO:1903307 8 0.175
ion homeostasis GO:0050801 230 0.174
regulation of protein polymerization GO:0032271 63 0.174
cellular response to lipid GO:0071396 127 0.174
regulation of protein complex assembly GO:0043254 147 0.174
single organism cellular localization GO:1902580 332 0.173
neutrophil degranulation GO:0043312 3 0.172
small gtpase mediated signal transduction GO:0007264 78 0.168
regulation of acute inflammatory response to antigenic stimulus GO:0002864 1 0.167
positive regulation of acute inflammatory response GO:0002675 2 0.167
arachidonic acid secretion GO:0050482 7 0.166
positive regulation of defense response GO:0031349 87 0.164
system process GO:0003008 349 0.162
regulation of sequestering of calcium ion GO:0051282 41 0.161
negative regulation of mitochondrial depolarization GO:0051902 2 0.160
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 20 0.160
negative regulation of protein phosphorylation GO:0001933 140 0.160
regulation of interferon gamma production GO:0032649 36 0.158
regulation of hemostasis GO:1900046 42 0.158
metal ion homeostasis GO:0055065 169 0.157
negative regulation of phosphorus metabolic process GO:0010563 267 0.157
response to bacterium GO:0009617 144 0.155
regulation of apoptotic signaling pathway GO:2001233 175 0.155
regulation of humoral immune response mediated by circulating immunoglobulin GO:0002923 3 0.154
negative regulation of protein tyrosine kinase activity GO:0061099 13 0.152
regulation of homeostatic process GO:0032844 121 0.152
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.151
actin cytoskeleton organization GO:0030036 207 0.150
negative regulation of catalytic activity GO:0043086 335 0.150
negative regulation of cellular component organization GO:0051129 235 0.149
negative regulation of phosphorylation GO:0042326 174 0.149
cytokine biosynthetic process GO:0042089 37 0.148
apoptotic signaling pathway GO:0097190 268 0.148
stress fiber assembly GO:0043149 40 0.147
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.147
positive regulation of hormone secretion GO:0046887 25 0.145
negative regulation of phosphate metabolic process GO:0045936 267 0.144
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.143
negative regulation of intracellular signal transduction GO:1902532 183 0.142
cell adhesion GO:0007155 325 0.141
oogenesis GO:0048477 2 0.140
positive regulation of endocytosis GO:0045807 42 0.140
b cell activation GO:0042113 33 0.140
positive regulation of intracellular transport GO:0032388 104 0.139
positive regulation of cell proliferation GO:0008284 301 0.138
secretion by cell GO:0032940 226 0.136
guanosine containing compound metabolic process GO:1901068 244 0.136
hormone transport GO:0009914 68 0.136
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.133
response to hormone GO:0009725 175 0.133
negative regulation of leukocyte activation GO:0002695 26 0.133
regulation of hormone secretion GO:0046883 57 0.132
phosphatidylinositol mediated signaling GO:0048015 55 0.132
positive regulation of apoptotic process GO:0043065 246 0.131
positive regulation of leukocyte proliferation GO:0070665 48 0.131
positive regulation of developmental process GO:0051094 314 0.131
associative learning GO:0008306 1 0.131
positive regulation of cell activation GO:0050867 81 0.130
response to external biotic stimulus GO:0043207 261 0.130
negative regulation of platelet aggregation GO:0090331 3 0.130
cellular homeostasis GO:0019725 196 0.129
regulation of immune effector process GO:0002697 91 0.127
cellular cation homeostasis GO:0030003 163 0.127
regulation of protein maturation GO:1903317 150 0.125
negative regulation of neurotrophin trk receptor signaling pathway GO:0051387 2 0.125
epithelial cell migration GO:0010631 119 0.125
negative regulation of apoptotic process GO:0043066 316 0.125
tyrosine phosphorylation of stat5 protein GO:0042506 13 0.125
response to drug GO:0042493 81 0.125
regulation of caveolin mediated endocytosis GO:2001286 2 0.124
lymphocyte proliferation GO:0046651 70 0.124
response to transforming growth factor beta GO:0071559 94 0.124
signal transduction by phosphorylation GO:0023014 297 0.123
regulation of body fluid levels GO:0050878 99 0.121
peptide hormone secretion GO:0030072 50 0.120
positive regulation of programmed cell death GO:0043068 249 0.118
regulation of jun kinase activity GO:0043506 27 0.118
regulation of b cell activation GO:0050864 24 0.117
positive regulation of store operated calcium channel activity GO:1901341 4 0.117
regulation of exocytosis GO:0017157 46 0.116
calcium ion transport GO:0006816 147 0.115
organic hydroxy compound transport GO:0015850 63 0.115
regulation of peptide hormone secretion GO:0090276 41 0.115
regulation of protein tyrosine kinase activity GO:0061097 36 0.114
leukocyte differentiation GO:0002521 98 0.112
regulation of mast cell degranulation GO:0043304 3 0.111
regulation of protein serine threonine kinase activity GO:0071900 179 0.111
regulation of organelle assembly GO:1902115 40 0.111
response to lipopolysaccharide GO:0032496 70 0.111
protein maturation GO:0051604 233 0.110
negative regulation of protein processing GO:0010955 142 0.110
positive regulation of mapk cascade GO:0043410 190 0.110
regulation of release of sequestered calcium ion into cytosol GO:0051279 27 0.109
regulation of map kinase activity GO:0043405 108 0.109
maintenance of location GO:0051235 112 0.108
regulation of t cell activation GO:0050863 77 0.108
leukocyte degranulation GO:0043299 11 0.107
negative regulation of alpha beta t cell proliferation GO:0046642 1 0.106
organelle localization GO:0051640 84 0.106
regulation of actin filament length GO:0030832 56 0.105
positive regulation of jun kinase activity GO:0043507 23 0.105
response to interferon gamma GO:0034341 39 0.103
negative regulation of apoptotic signaling pathway GO:2001234 97 0.102
b cell receptor signaling pathway GO:0050853 18 0.102
ameboidal type cell migration GO:0001667 135 0.100
cell cell signaling GO:0007267 155 0.100
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.099
platelet degranulation GO:0002576 2 0.099
positive regulation of protein phosphorylation GO:0001934 313 0.098
activation of cysteine type endopeptidase activity GO:0097202 57 0.097
tyrosine phosphorylation of stat3 protein GO:0042503 20 0.097
positive regulation of gtpase activity GO:0043547 166 0.096
ribonucleoside triphosphate catabolic process GO:0009203 391 0.096
divalent inorganic cation homeostasis GO:0072507 136 0.095
interferon gamma production GO:0032609 39 0.095
gland development GO:0048732 48 0.095
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.095
calcium ion homeostasis GO:0055074 122 0.095
zymogen activation GO:0031638 70 0.091
purine ribonucleotide catabolic process GO:0009154 404 0.091
negative regulation of protein maturation GO:1903318 142 0.089
fatty acid derivative biosynthetic process GO:1901570 18 0.089
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.089
tissue migration GO:0090130 119 0.088
cellular metal ion homeostasis GO:0006875 146 0.087
regulation of leukocyte mediated immunity GO:0002703 38 0.086
actin filament based process GO:0030029 224 0.086
dna replication GO:0006260 116 0.085
regulation of cytoplasmic transport GO:1903649 149 0.084
ras protein signal transduction GO:0007265 73 0.083
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.083
negative regulation of hydrolase activity GO:0051346 182 0.083
negative regulation of proteolysis GO:0045861 132 0.082
actomyosin structure organization GO:0031032 59 0.081
receptor mediated endocytosis GO:0006898 84 0.081
positive regulation of proteolysis GO:0045862 142 0.081
divalent inorganic cation transport GO:0072511 158 0.081
response to other organism GO:0051707 261 0.080
hemopoiesis GO:0030097 180 0.079
cytosolic calcium ion homeostasis GO:0051480 89 0.079
regulation of cell migration GO:0030334 289 0.079
regulation of cellular component movement GO:0051270 334 0.079
response to cytokine GO:0034097 232 0.078
regulation of response to interferon gamma GO:0060330 7 0.078
tyrosine phosphorylation of stat protein GO:0007260 33 0.078
eye photoreceptor cell differentiation GO:0001754 2 0.077
regulation of anatomical structure morphogenesis GO:0022603 286 0.076
post embryonic development GO:0009791 2 0.075
positive regulation of transferase activity GO:0051347 227 0.075
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.075
hormone secretion GO:0046879 65 0.075
cellular transition metal ion homeostasis GO:0046916 21 0.075
regulation of cellular component size GO:0032535 82 0.074
positive regulation of lipid kinase activity GO:0090218 13 0.074
tumor necrosis factor production GO:0032640 43 0.074
podosome assembly GO:0071800 6 0.073
mast cell activation GO:0045576 6 0.073
biological adhesion GO:0022610 331 0.073
regulation of actin filament polymerization GO:0030833 50 0.073
lipid biosynthetic process GO:0008610 177 0.072
cellular response to oxygen containing compound GO:1901701 276 0.072
regulation of epithelial cell migration GO:0010632 93 0.072
organelle assembly GO:0070925 176 0.071
regulation of phosphatidylinositol 3 kinase activity GO:0043551 14 0.071
regulation of protein processing GO:0070613 150 0.071
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.070
positive regulation of cytokine mediated signaling pathway GO:0001961 12 0.070
response to biotic stimulus GO:0009607 276 0.070
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 12 0.070
blood vessel endothelial cell migration GO:0043534 42 0.069
gtp catabolic process GO:0006184 237 0.069
b cell proliferation GO:0042100 22 0.069
gamma delta t cell activation GO:0046629 3 0.068
response to oxidative stress GO:0006979 121 0.068
negative regulation of protein homooligomerization GO:0032463 4 0.067
cellular protein complex assembly GO:0043623 188 0.067
negative regulation of protein complex assembly GO:0031333 43 0.067
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.067
cytosolic calcium ion transport GO:0060401 48 0.066
actin polymerization or depolymerization GO:0008154 56 0.066
small molecule biosynthetic process GO:0044283 157 0.066
positive regulation of insulin secretion GO:0032024 10 0.066
response to organonitrogen compound GO:0010243 156 0.065
second messenger mediated signaling GO:0019932 78 0.065
mapk cascade GO:0000165 288 0.065
negative regulation of immune system process GO:0002683 136 0.064
regulation of anatomical structure size GO:0090066 101 0.064
calcium mediated signaling GO:0019722 44 0.063
myeloid leukocyte mediated immunity GO:0002444 10 0.063
insulin secretion GO:0030073 39 0.063
nucleoside triphosphate metabolic process GO:0009141 422 0.063
negative regulation of protein kinase activity GO:0006469 98 0.063
negative regulation of endopeptidase activity GO:0010951 84 0.062
regulation of lipid metabolic process GO:0019216 96 0.062
phagocytosis GO:0006909 42 0.062
negative regulation of cellular protein metabolic process GO:0032269 353 0.062
ribonucleoside triphosphate metabolic process GO:0009199 412 0.062
sequestering of metal ion GO:0051238 24 0.062
cell morphogenesis GO:0000902 296 0.062
cellular response to cytokine stimulus GO:0071345 181 0.062
positive regulation of lymphocyte activation GO:0051251 73 0.061
regulation of membrane depolarization GO:0003254 19 0.061
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.061
protein polymerization GO:0051258 71 0.061
negative regulation of peptidase activity GO:0010466 91 0.060
organophosphate catabolic process GO:0046434 430 0.060
single organism cell adhesion GO:0098602 179 0.060
regulation of cysteine type endopeptidase activity GO:2000116 127 0.059
phosphatidylinositol metabolic process GO:0046488 53 0.059
response to peptide GO:1901652 65 0.058
t cell differentiation in thymus GO:0033077 4 0.058
organophosphate biosynthetic process GO:0090407 163 0.057
response to reactive oxygen species GO:0000302 61 0.056
regulation of gtp catabolic process GO:0033124 180 0.056
regulation of calcium ion transport GO:0051924 79 0.056
membrane organization GO:0061024 292 0.055
positive regulation of gtp catabolic process GO:0033126 166 0.055
positive regulation of lymphocyte proliferation GO:0050671 46 0.055
negative regulation of transferase activity GO:0051348 124 0.055
positive regulation of apoptotic signaling pathway GO:2001235 70 0.055
acute inflammatory response to antigenic stimulus GO:0002438 1 0.055
purine nucleoside catabolic process GO:0006152 398 0.055
regulation of endocytosis GO:0030100 72 0.054
leukocyte chemotaxis GO:0030595 76 0.053
cellular macromolecule catabolic process GO:0044265 380 0.053
glycerolipid metabolic process GO:0046486 107 0.053
inflammatory response to antigenic stimulus GO:0002437 4 0.052
negative regulation of myeloid cell apoptotic process GO:0033033 4 0.051
purine nucleoside triphosphate metabolic process GO:0009144 412 0.051
epithelium development GO:0060429 227 0.051
negative regulation of cell proliferation GO:0008285 228 0.050
lymphocyte differentiation GO:0030098 35 0.050
extrinsic apoptotic signaling pathway GO:0097191 119 0.050
hematopoietic or lymphoid organ development GO:0048534 186 0.050
compound eye development GO:0048749 1 0.050
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.049
response to nitrogen compound GO:1901698 184 0.049
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.048
i kappab kinase nf kappab signaling GO:0007249 166 0.048
regulation of metal ion transport GO:0010959 120 0.048
icosanoid transport GO:0071715 11 0.048
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.048
regulation of cell morphogenesis GO:0022604 153 0.048
negative regulation of kinase activity GO:0033673 106 0.048
actin filament bundle organization GO:0061572 54 0.047
positive regulation of cell projection organization GO:0031346 64 0.047
regulation of tumor necrosis factor production GO:0032680 43 0.047
purine ribonucleoside catabolic process GO:0046130 398 0.047
photoreceptor cell differentiation GO:0046530 2 0.047
regulation of actin cytoskeleton organization GO:0032956 116 0.047
regulation of protein localization GO:0032880 296 0.046
cdc42 protein signal transduction GO:0032488 4 0.046
positive regulation of nucleotide catabolic process GO:0030813 185 0.046
positive regulation of cellular catabolic process GO:0031331 284 0.046
neurological system process GO:0050877 163 0.046
activation of jun kinase activity GO:0007257 7 0.045
cell chemotaxis GO:0060326 112 0.045
positive regulation of aldosterone biosynthetic process GO:0032349 2 0.045
carbohydrate metabolic process GO:0005975 207 0.045
adaptive immune response GO:0002250 49 0.045
long chain fatty acid transport GO:0015909 18 0.045
cellular response to acid chemical GO:0071229 44 0.044
regulation of leukocyte proliferation GO:0070663 67 0.043
regulation of actin filament based process GO:0032970 141 0.043
ribonucleoside catabolic process GO:0042454 406 0.042
cardiovascular system development GO:0072358 262 0.042
regulation of nucleotide catabolic process GO:0030811 205 0.042
transition metal ion homeostasis GO:0055076 31 0.042
lysosome localization GO:0032418 10 0.042
dephosphorylation GO:0016311 209 0.042
regulation of peptide transport GO:0090087 62 0.042
positive regulation of alpha beta t cell proliferation GO:0046641 5 0.042
positive regulation of neurogenesis GO:0050769 49 0.041
positive regulation of neuron differentiation GO:0045666 40 0.041
glycerophospholipid biosynthetic process GO:0046474 40 0.041
positive regulation of lipopolysaccharide mediated signaling pathway GO:0031666 4 0.041
positive regulation of peptidase activity GO:0010952 88 0.040
positive regulation of cell death GO:0010942 263 0.040
tissue homeostasis GO:0001894 63 0.040
regulation of early endosome to late endosome transport GO:2000641 6 0.040
cytokine metabolic process GO:0042107 38 0.040
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 22 0.040
neuron differentiation GO:0030182 138 0.040
t cell selection GO:0045058 4 0.039
response to acid chemical GO:0001101 66 0.039
positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 3 0.039
positive regulation of phagocytosis GO:0050766 15 0.039
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.038
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.038
regulation of locomotion GO:0040012 329 0.038
nucleoside catabolic process GO:0009164 408 0.038
regulation of transforming growth factor beta1 production GO:0032908 3 0.037
negative regulation of t cell receptor signaling pathway GO:0050860 4 0.037
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.037
organic hydroxy compound metabolic process GO:1901615 147 0.037
glycerolipid biosynthetic process GO:0045017 51 0.036
regulation of membrane potential GO:0042391 95 0.036
regulation of protein homooligomerization GO:0032462 11 0.036
response to molecule of bacterial origin GO:0002237 82 0.036
negative regulation of protein modification process GO:0031400 200 0.036
positive regulation of leukocyte mediated immunity GO:0002705 24 0.036
reproductive process GO:0022414 106 0.036
myeloid leukocyte differentiation GO:0002573 60 0.036

BLNK disease predictions

Disease DO term ID Size Probability Func Analog Org
primary immunodeficiency disease DOID:612 36 0.933
immune system disease DOID:2914 155 0.933
b cell deficiency DOID:2115 17 0.933
blood protein disease DOID:620 16 0.768
hematopoietic system disease DOID:74 100 0.768
kidney disease DOID:557 36 0.439
urinary system disease DOID:18 40 0.439
agammaglobulinemia DOID:2583 16 0.322
disease of metabolism DOID:0014667 295 0.060
musculoskeletal system disease DOID:17 223 0.050
central nervous system disease DOID:331 186 0.041
nervous system disease DOID:863 431 0.041