|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
1.000
|
|
|
|
histone h2a monoubiquitination
|
GO:0035518 |
11 |
1.000
|
Human |
|
|
histone monoubiquitination
|
GO:0010390 |
20 |
1.000
|
Human |
|
|
histone h2a ubiquitination
|
GO:0033522 |
17 |
1.000
|
Human |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.998
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.994
|
|
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.985
|
Human Mouse |
|
|
regionalization
|
GO:0003002 |
29 |
0.962
|
Mouse |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.911
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.910
|
Mouse |
|
|
response to radiation
|
GO:0009314 |
151 |
0.888
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.886
|
Fly |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.886
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.872
|
Fly |
|
|
positive regulation of ligase activity
|
GO:0051351 |
19 |
0.828
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.813
|
Mouse |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.805
|
Mouse |
|
|
cell development
|
GO:0048468 |
328 |
0.758
|
Fly |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.733
|
Fly |
|
|
chromatin modification
|
GO:0016568 |
298 |
0.731
|
Human Mouse Fly |
|
|
histone modification
|
GO:0016570 |
251 |
0.719
|
Human Mouse |
|
|
protein monoubiquitination
|
GO:0006513 |
39 |
0.714
|
Human |
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.709
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.703
|
Mouse |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.683
|
Fly |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.681
|
Fly |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.675
|
Mouse |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.674
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.662
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.636
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.613
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.607
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.565
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.560
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.559
|
Fly |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.556
|
Mouse |
|
|
spinal cord development
|
GO:0021510 |
4 |
0.546
|
|
|
|
chromatin silencing
|
GO:0006342 |
12 |
0.542
|
Fly |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.536
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.533
|
Human Mouse |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.521
|
Mouse |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.498
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.478
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.448
|
Human Mouse Fly |
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.446
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.439
|
Mouse |
|
|
rna splicing via transesterification reactions with bulged adenosine as nucleophile
|
GO:0000377 |
89 |
0.426
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.415
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.411
|
Fly |
|
|
embryo development
|
GO:0009790 |
123 |
0.387
|
Zebrafish Mouse Fly |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.384
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.380
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.380
|
Fly |
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.376
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.374
|
|
|
|
central nervous system neuron development
|
GO:0021954 |
7 |
0.366
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
21 |
0.364
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.362
|
Mouse |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.354
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.353
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.352
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.331
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.324
|
|
|
|
eye morphogenesis
|
GO:0048592 |
16 |
0.312
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
33 |
0.312
|
|
|
|
gastrulation with mouth forming second
|
GO:0001702 |
1 |
0.301
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.299
|
Fly |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.298
|
Fly |
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.298
|
|
|
|
rna splicing
|
GO:0008380 |
131 |
0.295
|
|
|
|
memory
|
GO:0007613 |
3 |
0.292
|
|
|
|
mrna splicing via spliceosome
|
GO:0000398 |
89 |
0.287
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.286
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.284
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.275
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.265
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.254
|
|
|
|
response to gamma radiation
|
GO:0010332 |
14 |
0.247
|
|
|
|
regulation of axon guidance
|
GO:1902667 |
3 |
0.247
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.243
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.242
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.238
|
|
|
|
mrna processing
|
GO:0006397 |
133 |
0.236
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.229
|
Mouse Fly |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.228
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.223
|
Fly |
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.213
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.209
|
Zebrafish Mouse Fly |
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.205
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.204
|
Mouse |
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.198
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.197
|
|
|
|
neuron remodeling
|
GO:0016322 |
2 |
0.196
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.181
|
Mouse |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.178
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.166
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.166
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.165
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.162
|
Fly |
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.159
|
Fly |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.158
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.158
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.153
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.153
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.152
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.146
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.144
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.142
|
|
|
|
developmental maturation
|
GO:0021700 |
28 |
0.141
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.140
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.139
|
Fly |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.139
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.139
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.138
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.136
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.133
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.129
|
|
|
|
negative regulation of gene expression epigenetic
|
GO:0045814 |
19 |
0.128
|
Fly |
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.127
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
40 |
0.127
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.125
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.124
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.124
|
|
|
|
camera type eye morphogenesis
|
GO:0048593 |
12 |
0.123
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.119
|
Fly |
|
|
regulation of developmental growth
|
GO:0048638 |
30 |
0.118
|
|
|
|
cartilage development
|
GO:0051216 |
31 |
0.115
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.112
|
Mouse |
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.107
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.105
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.104
|
Fly |
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.102
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.100
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.095
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.095
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.094
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.093
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.093
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.091
|
Mouse |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.090
|
Fly |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.087
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.085
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.081
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.076
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.075
|
|
|
|
circadian sleep wake cycle
|
GO:0042745 |
2 |
0.075
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.074
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
9 |
0.073
|
Mouse |
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.072
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.071
|
|
|
|
sleep
|
GO:0030431 |
2 |
0.070
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.069
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
32 |
0.068
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.068
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.067
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.067
|
|
|
|
nucleic acid transport
|
GO:0050657 |
39 |
0.067
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.066
|
|
|
|
rostrocaudal neural tube patterning
|
GO:0021903 |
1 |
0.066
|
Mouse |
|
|
chromatin assembly
|
GO:0031497 |
61 |
0.066
|
|
|
|
neural tube patterning
|
GO:0021532 |
2 |
0.065
|
Mouse |
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.065
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.064
|
|
|
|
embryonic cranial skeleton morphogenesis
|
GO:0048701 |
6 |
0.064
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.063
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.060
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.058
|
Mouse |
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
9 |
0.058
|
Mouse |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.058
|
|
|
|
growth
|
GO:0040007 |
202 |
0.057
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.056
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.055
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.055
|
Fly |
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.055
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.054
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.053
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.053
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.053
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.053
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.052
|
|
|
|
regulation of synaptic transmission
|
GO:0050804 |
11 |
0.052
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.052
|
|
|
|
neuron projection guidance
|
GO:0097485 |
12 |
0.050
|
Fly |
|
|
response to alcohol
|
GO:0097305 |
64 |
0.050
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.050
|
|
|
|
short term memory
|
GO:0007614 |
1 |
0.049
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.048
|
Mouse |
|
|
regulation of rna splicing
|
GO:0043484 |
62 |
0.048
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.048
|
|
|
|
mating
|
GO:0007618 |
1 |
0.047
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.047
|
|
|
|
rna localization
|
GO:0006403 |
41 |
0.046
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.046
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.045
|
|
|
|
regulation of histone h3 k27 methylation
|
GO:0061085 |
4 |
0.044
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.044
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.044
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.044
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.043
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.043
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.043
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.043
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
24 |
0.042
|
Mouse |
|
|
regulation of axon extension involved in axon guidance
|
GO:0048841 |
2 |
0.042
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.042
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.042
|
Zebrafish Mouse |
|
|
alternative mrna splicing via spliceosome
|
GO:0000380 |
27 |
0.041
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.041
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.041
|
Fly |
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.040
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.039
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.039
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.039
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.039
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.039
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.038
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.038
|
Mouse |
|
|
long term synaptic potentiation
|
GO:0060291 |
1 |
0.037
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.037
|
|
|
|
chromatin remodeling
|
GO:0006338 |
55 |
0.037
|
Fly |
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.037
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.037
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.036
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.036
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.036
|
|
|
|
circadian sleep wake cycle sleep
|
GO:0050802 |
2 |
0.036
|
|
|
|
negative regulation of protein kinase b signaling
|
GO:0051898 |
17 |
0.034
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.033
|
|
|
|
synapse organization
|
GO:0050808 |
14 |
0.033
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.033
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.033
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.033
|
|
|
|
response to retinoic acid
|
GO:0032526 |
33 |
0.032
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.032
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.032
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.032
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.031
|
|
|
|
establishment of rna localization
|
GO:0051236 |
39 |
0.031
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.031
|
Zebrafish Mouse |
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.030
|
|
|
|
positive regulation of myeloid cell apoptotic process
|
GO:0033034 |
2 |
0.030
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.030
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.030
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
68 |
0.030
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.030
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.029
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.029
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.029
|
|
|
|
dendrite morphogenesis
|
GO:0048813 |
14 |
0.029
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.028
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.028
|
|
|
|
regulation of mrna splicing via spliceosome
|
GO:0048024 |
32 |
0.028
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.028
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.028
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.028
|
|
|
|
regulation of mrna processing
|
GO:0050684 |
48 |
0.028
|
|
|
|
protein complex disassembly
|
GO:0043241 |
52 |
0.027
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.027
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.027
|
Mouse |
|
|
appendage development
|
GO:0048736 |
23 |
0.027
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.026
|
|
|
|
mrna transport
|
GO:0051028 |
30 |
0.026
|
|
|
|
negative regulation of neurological system process
|
GO:0031645 |
2 |
0.026
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.026
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.026
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.026
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.026
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.026
|
|
|
|
ribonucleoprotein complex assembly
|
GO:0022618 |
78 |
0.026
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.026
|
|
|
|
system process
|
GO:0003008 |
349 |
0.026
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.025
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.025
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.025
|
Mouse |
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.025
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.025
|
|
|
|
regulation of axon regeneration
|
GO:0048679 |
1 |
0.024
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.024
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.024
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.024
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.024
|
|
|
|
dendritic spine morphogenesis
|
GO:0060997 |
3 |
0.024
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.024
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.024
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.024
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.023
|
|
|
|
negative regulation of translation
|
GO:0017148 |
37 |
0.023
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
17 |
0.023
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.023
|
|
|
|
regulation of cgmp biosynthetic process
|
GO:0030826 |
4 |
0.023
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.023
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.022
|
|
|
|
convergent extension
|
GO:0060026 |
1 |
0.022
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.022
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.022
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.022
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.021
|
|
|
|
circadian sleep wake cycle process
|
GO:0022410 |
2 |
0.021
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.021
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.021
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.021
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.021
|
|
|
|
cgmp metabolic process
|
GO:0046068 |
19 |
0.021
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.021
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.021
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.021
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.020
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.020
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.020
|
|
|
|
cell maturation
|
GO:0048469 |
11 |
0.020
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.020
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.020
|
|
|
|
camera type eye development
|
GO:0043010 |
25 |
0.020
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.020
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
15 |
0.020
|
|
|
|
regulation of chondrocyte differentiation
|
GO:0032330 |
9 |
0.020
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.020
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.020
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.020
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.020
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.020
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.020
|
|
|
|
sister chromatid cohesion
|
GO:0007062 |
24 |
0.019
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.019
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.019
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.019
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.019
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.019
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.019
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.018
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.018
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.018
|
|
|
|
regulation of dendrite morphogenesis
|
GO:0048814 |
11 |
0.018
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.018
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.018
|
|
|
|
rhythmic process
|
GO:0048511 |
31 |
0.018
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.018
|
|
|
|
negative regulation of dendritic spine development
|
GO:0061000 |
1 |
0.018
|
|
|
|
regulation of dendrite development
|
GO:0050773 |
18 |
0.018
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.018
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.018
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.018
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.017
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.017
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.017
|
|
|
|
detection of mechanical stimulus involved in sensory perception
|
GO:0050974 |
1 |
0.017
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.017
|
|
|
|
axoneme assembly
|
GO:0035082 |
3 |
0.017
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.017
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.017
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.017
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.017
|
|
|
|
regulation of synapse assembly
|
GO:0051963 |
5 |
0.017
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.017
|
|
|
|
axon extension
|
GO:0048675 |
13 |
0.017
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.017
|
|
|
|
ribonucleoprotein complex localization
|
GO:0071166 |
4 |
0.017
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.017
|
|
|
|
trophectodermal cell differentiation
|
GO:0001829 |
3 |
0.017
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.017
|
|
|
|
central nervous system myelination
|
GO:0022010 |
1 |
0.017
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.016
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.016
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.016
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.016
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.016
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.016
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.016
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.016
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.016
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.016
|
|
|
|
axis specification
|
GO:0009798 |
12 |
0.016
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.015
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.015
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.015
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.015
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.015
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.015
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.015
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.015
|
|
|
|
single organism behavior
|
GO:0044708 |
28 |
0.015
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.015
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.014
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.014
|
|
|
|
nucleobase containing compound transport
|
GO:0015931 |
51 |
0.014
|
|
|
|
renal sodium ion transport
|
GO:0003096 |
2 |
0.014
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.014
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.014
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.014
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.014
|
|
|
|
head development
|
GO:0060322 |
108 |
0.014
|
Zebrafish Mouse |
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.014
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.014
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.014
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.014
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.014
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.014
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.013
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
0.013
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.013
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.013
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.013
|
|
|
|
regulation of axonogenesis
|
GO:0050770 |
16 |
0.013
|
|
|
|
blastocyst formation
|
GO:0001825 |
3 |
0.013
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
1 |
0.013
|
|
|
|
regulation of signal transduction by p53 class mediator
|
GO:1901796 |
26 |
0.013
|
|
|
|
regulation of mrna metabolic process
|
GO:1903311 |
53 |
0.013
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.013
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.013
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.013
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.012
|
|
|
|
negative regulation of cell morphogenesis involved in differentiation
|
GO:0010771 |
24 |
0.012
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.012
|
|
|
|
negative regulation of developmental growth
|
GO:0048640 |
10 |
0.012
|
|
|
|
histone methylation
|
GO:0016571 |
60 |
0.012
|
|
|
|
viral transcription
|
GO:0019083 |
35 |
0.012
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.012
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.012
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.012
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.012
|
|
|
|
regulation of cgmp metabolic process
|
GO:0030823 |
9 |
0.012
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.012
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
38 |
0.012
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.011
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.011
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.011
|
Mouse |
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.011
|
|
|
|
ncrna processing
|
GO:0034470 |
83 |
0.011
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.011
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.011
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.011
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.011
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.011
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
43 |
0.011
|
|
|
|
presynaptic membrane organization
|
GO:0097090 |
3 |
0.011
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.011
|
|
|
|
dendritic spine organization
|
GO:0097061 |
4 |
0.011
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.011
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.011
|
|
|
|
phosphatidylinositol dephosphorylation
|
GO:0046856 |
7 |
0.011
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.011
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.011
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.010
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.010
|
Mouse |
|
|
ear development
|
GO:0043583 |
14 |
0.010
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.010
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.010
|
|
|
|
positive regulation of cgmp metabolic process
|
GO:0030825 |
5 |
0.010
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.010
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.010
|
|
|
|
negative regulation of neuron projection development
|
GO:0010977 |
15 |
0.010
|
|
|
|
regulation of neuroblast proliferation
|
GO:1902692 |
3 |
0.010
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.010
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.010
|
|
|
|
gene silencing by rna
|
GO:0031047 |
26 |
0.010
|
|
