|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.986
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.848
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.847
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.787
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.769
|
Fly |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.739
|
Fly |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.726
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.710
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.701
|
Fly |
|
|
ossification
|
GO:0001503 |
121 |
0.692
|
Zebrafish |
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.688
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.674
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.669
|
Fly |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.650
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.647
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.644
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.618
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.617
|
|
|
|
endoderm formation
|
GO:0001706 |
33 |
0.614
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.607
|
Fly |
|
|
membrane organization
|
GO:0061024 |
292 |
0.600
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.574
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.563
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.561
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.560
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.552
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.541
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.533
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.516
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.502
|
|
|
|
collagen metabolic process
|
GO:0032963 |
28 |
0.496
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.492
|
Fly |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.478
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.470
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.462
|
|
|
|
multicellular organismal metabolic process
|
GO:0044236 |
34 |
0.449
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.441
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.435
|
|
|
|
spinal cord dorsal ventral patterning
|
GO:0021513 |
2 |
0.431
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.426
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.411
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.399
|
|
|
|
negative regulation of smoothened signaling pathway
|
GO:0045879 |
3 |
0.392
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.374
|
Fly |
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
4 |
0.366
|
Zebrafish |
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.354
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.346
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.325
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.325
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.322
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.316
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.313
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.312
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
17 |
0.295
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.290
|
|
|
|
multicellular organismal macromolecule metabolic process
|
GO:0044259 |
29 |
0.281
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.276
|
Fly |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.275
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.261
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.241
|
Fly |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.235
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
16 |
0.234
|
Fly |
|
|
embryo development
|
GO:0009790 |
123 |
0.234
|
Fly |
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.216
|
|
|
|
ectodermal placode formation
|
GO:0060788 |
1 |
0.215
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.214
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.213
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.210
|
Fly |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.208
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.203
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.201
|
Fly |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.201
|
|
|
|
gastrulation with mouth forming second
|
GO:0001702 |
1 |
0.199
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.194
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.192
|
Fly |
|
|
sensory organ morphogenesis
|
GO:0090596 |
21 |
0.187
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.177
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.174
|
|
|
|
convergent extension involved in gastrulation
|
GO:0060027 |
1 |
0.174
|
|
|
|
ectodermal placode development
|
GO:0071696 |
1 |
0.172
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.168
|
|
|
|
positive regulation of keratinocyte migration
|
GO:0051549 |
4 |
0.165
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.157
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.154
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.154
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.150
|
Fly |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.150
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.148
|
|
|
|
cartilage development
|
GO:0051216 |
31 |
0.145
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.142
|
Fly |
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.138
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.138
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.136
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.136
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
3 |
0.133
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.131
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.130
|
|
|
|
appendage development
|
GO:0048736 |
23 |
0.129
|
Zebrafish Fly |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.127
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.126
|
|
|
|
replacement ossification
|
GO:0036075 |
1 |
0.125
|
|
|
|
regulation of keratinocyte migration
|
GO:0051547 |
4 |
0.123
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
4 |
0.123
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.122
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.122
|
|
|
|
response to increased oxygen levels
|
GO:0036296 |
4 |
0.121
|
|
|
|
otic vesicle development
|
GO:0071599 |
1 |
0.120
|
|
|
|
basement membrane organization
|
GO:0071711 |
3 |
0.119
|
|
|
|
growth
|
GO:0040007 |
202 |
0.117
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.113
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.111
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.110
|
|
|
|
dorsal ventral axis specification
|
GO:0009950 |
7 |
0.108
|
Fly |
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.107
|
|
|
|
ectodermal placode morphogenesis
|
GO:0071697 |
1 |
0.107
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.106
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.105
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.103
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.102
|
Fly |
|
|
endocrine system development
|
GO:0035270 |
26 |
0.099
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.098
|
|
|
|
head development
|
GO:0060322 |
108 |
0.097
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.095
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.091
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.091
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.090
|
|
|
|
bone development
|
GO:0060348 |
26 |
0.090
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.089
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.089
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
41 |
0.089
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.088
|
Fly |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.086
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.086
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.085
|
Fly |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.085
|
|
|
|
convergent extension
|
GO:0060026 |
1 |
0.084
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.084
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.084
|
Fly |
|
|
smoothened signaling pathway
|
GO:0007224 |
14 |
0.080
|
|
|
|
endoderm development
|
GO:0007492 |
33 |
0.080
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.080
|
Fly |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.080
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.079
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.079
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.078
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.077
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.076
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.074
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.074
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.073
|
Fly |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.072
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.070
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.069
|
Fly |
|
|
spinal cord patterning
|
GO:0021511 |
2 |
0.069
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.069
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.069
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.067
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.067
|
Fly |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.067
|
Fly |
|
|
cartilage development involved in endochondral bone morphogenesis
|
GO:0060351 |
2 |
0.067
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.066
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.066
|
|
|
|
endochondral ossification
|
GO:0001958 |
1 |
0.066
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.065
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.065
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.065
|
|
|
|
proteoglycan metabolic process
|
GO:0006029 |
29 |
0.065
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.065
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.064
|
|
|
|
smoothened signaling pathway involved in ventral spinal cord patterning
|
GO:0021910 |
0 |
0.064
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.064
|
Fly |
|
|
sensory organ development
|
GO:0007423 |
52 |
0.063
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.063
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.062
|
|
|
|
positive regulation of odontogenesis
|
GO:0042482 |
3 |
0.062
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.060
|
|
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
8 |
0.059
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.059
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.059
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.058
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.058
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.058
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.058
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.058
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.057
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
24 |
0.057
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.057
|
|
|
|
collagen catabolic process
|
GO:0030574 |
10 |
0.056
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.056
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
15 |
0.056
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.056
|
Fly |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.056
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.055
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.055
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.055
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.054
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.054
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.054
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.053
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.053
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.053
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.052
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.052
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.052
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.052
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.051
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.051
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.051
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.051
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.050
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.050
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.050
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.050
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.050
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.049
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.049
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.049
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.049
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.048
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.048
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.048
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.048
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.047
|
|
|
|
proteoglycan catabolic process
|
GO:0030167 |
3 |
0.047
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.047
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.047
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.046
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.046
|
|
|
|
embryonic viscerocranium morphogenesis
|
GO:0048703 |
1 |
0.046
|
|
|
|
sensory perception of light stimulus
|
GO:0050953 |
35 |
0.045
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.044
|
|
|
|
regulation of mesenchymal cell proliferation
|
GO:0010464 |
5 |
0.044
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.044
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.043
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.043
|
Fly |
|
|
glial cell migration
|
GO:0008347 |
4 |
0.043
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.043
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.043
|
Fly |
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.043
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.043
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.042
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.042
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.042
|
Fly |
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.042
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.041
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.041
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.041
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.041
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.041
|
Fly |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.040
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.040
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.040
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.040
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.040
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
9 |
0.039
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.039
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.039
|
Zebrafish Fly |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.039
|
|
|
|
ear morphogenesis
|
GO:0042471 |
7 |
0.039
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.038
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.038
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.038
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
21 |
0.038
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.038
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.038
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.038
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.038
|
|
|
|
sulfur compound biosynthetic process
|
GO:0044272 |
38 |
0.037
|
|
|
|
oxidative stress induced premature senescence
|
GO:0090403 |
3 |
0.037
|
|
|
|
focal adhesion assembly
|
GO:0048041 |
30 |
0.037
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.036
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.035
|
Fly |
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.035
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.035
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.035
|
Zebrafish Fly |
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.035
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.035
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.034
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.034
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.034
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.034
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.034
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.033
|
Fly |
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.033
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.032
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.032
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.032
|
|
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.032
|
|
|
|
positive regulation of vascular endothelial growth factor signaling pathway
|
GO:1900748 |
3 |
0.031
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.031
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.031
|
|
|
|
negative regulation of embryonic development
|
GO:0045992 |
4 |
0.031
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.031
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.031
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.030
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.030
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.030
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.030
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.030
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.030
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.030
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.029
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.029
|
Fly |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.029
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.029
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.029
|
Fly |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.029
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.029
|
|
|
|
negative regulation of hydrogen peroxide metabolic process
|
GO:0010727 |
3 |
0.029
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.029
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.029
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.029
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.028
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.028
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.028
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.028
|
|
|
|
regulation of endodermal cell differentiation
|
GO:1903224 |
3 |
0.028
|
|
|
|
regulation of cell junction assembly
|
GO:1901888 |
29 |
0.028
|
|
|
|
visual perception
|
GO:0007601 |
27 |
0.028
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.028
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.027
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.027
|
|
|
|
response to hyperoxia
|
GO:0055093 |
4 |
0.027
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.027
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.027
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.027
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.027
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.027
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.026
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.026
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.026
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.026
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.026
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.026
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.026
|
|
|
|
branching involved in salivary gland morphogenesis
|
GO:0060445 |
1 |
0.025
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.025
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.025
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.025
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.025
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.025
|
|
|
|
negative regulation of cell substrate adhesion
|
GO:0010812 |
24 |
0.025
|
|
|
|
semaphorin plexin signaling pathway
|
GO:0071526 |
4 |
0.025
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.024
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.024
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.024
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.024
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.024
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.024
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.024
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
15 |
0.024
|
Zebrafish |
|
|
brain development
|
GO:0007420 |
97 |
0.024
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
11 |
0.024
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.024
|
|
|
|
response to activity
|
GO:0014823 |
0 |
0.024
|
|
|
|
mesenchymal cell proliferation
|
GO:0010463 |
7 |
0.024
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.024
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
17 |
0.024
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
15 |
0.024
|
Zebrafish Fly |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.024
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.023
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
30 |
0.023
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.023
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.023
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.023
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.023
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.023
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.023
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.023
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.023
|
|
|
|
somite development
|
GO:0061053 |
7 |
0.023
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.023
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.022
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.022
|
|
|
|
chondroitin sulfate metabolic process
|
GO:0030204 |
7 |
0.022
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.022
|
|
|
|
regulation of cartilage development
|
GO:0061035 |
12 |
0.022
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.022
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.022
|
|
|
|
positive regulation of stem cell proliferation
|
GO:2000648 |
10 |
0.022
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.022
|
|
|
|
specification of symmetry
|
GO:0009799 |
16 |
0.022
|
Zebrafish |
|
|
bone trabecula formation
|
GO:0060346 |
1 |
0.022
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.022
|
|
|
|
mesoderm formation
|
GO:0001707 |
10 |
0.021
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.021
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.021
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.021
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.021
|
|
|
|
embryonic cranial skeleton morphogenesis
|
GO:0048701 |
6 |
0.021
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.021
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.021
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.020
|
|
|
|
cellular response to hepatocyte growth factor stimulus
|
GO:0035729 |
6 |
0.020
|
|
|
|
dermatan sulfate proteoglycan biosynthetic process
|
GO:0050651 |
4 |
0.020
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.020
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.020
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.020
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.020
|
|
|
|
heart looping
|
GO:0001947 |
7 |
0.020
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.020
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.020
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.020
|
Fly |
|
|
extracellular structure organization
|
GO:0043062 |
41 |
0.020
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.020
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.020
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.019
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.019
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.019
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.019
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.019
|
|
|
|
negative regulation of fibroblast growth factor receptor signaling pathway
|
GO:0040037 |
2 |
0.019
|
|
|
|
cellular response to interleukin 1
|
GO:0071347 |
35 |
0.019
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.019
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.019
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.019
|
Fly |
|
|
multicellular organismal catabolic process
|
GO:0044243 |
12 |
0.019
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.018
|
|
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
41 |
0.018
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.018
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.018
|
Fly |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.018
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
4 |
0.018
|
|
|
|
aging
|
GO:0007568 |
66 |
0.018
|
|
|
|
embryonic pattern specification
|
GO:0009880 |
5 |
0.018
|
Fly |
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.018
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
39 |
0.018
|
|
|
|
negative regulation of axon extension
|
GO:0030517 |
2 |
0.018
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.018
|
|
|
|
inner ear development
|
GO:0048839 |
8 |
0.018
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.018
|
|
|
|
embryonic axis specification
|
GO:0000578 |
5 |
0.018
|
Fly |
|
|
epithelium migration
|
GO:0090132 |
119 |
0.018
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.018
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.017
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.017
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.017
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.017
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.017
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.017
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.017
|
|
|
|
glycosaminoglycan metabolic process
|
GO:0030203 |
35 |
0.017
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.017
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.017
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.017
|
|
|
|
metanephric nephron epithelium development
|
GO:0072243 |
4 |
0.017
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.017
|
|
|
|
regulation of odontogenesis
|
GO:0042481 |
4 |
0.017
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.017
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.017
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.017
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.016
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.016
|
|
|
|
stem cell proliferation
|
GO:0072089 |
25 |
0.016
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.016
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.016
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.016
|
|
|
|
chondroitin sulfate biosynthetic process
|
GO:0030206 |
7 |
0.016
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.016
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.016
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.016
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.016
|
|
|
|
aminoglycan biosynthetic process
|
GO:0006023 |
29 |
0.016
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.016
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.016
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.016
|
|
|
|
patterning of blood vessels
|
GO:0001569 |
2 |
0.016
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.015
|
|
|
|
embryonic skeletal joint morphogenesis
|
GO:0060272 |
2 |
0.015
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.015
|
|
|
|
glycosaminoglycan biosynthetic process
|
GO:0006024 |
27 |
0.015
|
|
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.015
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.015
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.015
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.015
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.015
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.015
|
|
|
|
positive regulation of receptor binding
|
GO:1900122 |
1 |
0.015
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.015
|
|
|
|
cell adhesion mediated by integrin
|
GO:0033627 |
27 |
0.015
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.015
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.015
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.015
|
|
