|
|
negative regulation of glomerulus development
|
GO:0090194 |
2 |
1.000
|
|
|
|
positive regulation of aldosterone metabolic process
|
GO:0032346 |
2 |
0.999
|
|
|
|
negative regulation of kidney development
|
GO:0090185 |
2 |
0.998
|
|
|
|
negative regulation of cell proliferation involved in kidney development
|
GO:1901723 |
2 |
0.997
|
|
|
|
mesendoderm development
|
GO:0048382 |
1 |
0.997
|
|
|
|
negative regulation of glucocorticoid biosynthetic process
|
GO:0031947 |
4 |
0.996
|
|
|
|
positive regulation of pathway restricted smad protein phosphorylation
|
GO:0010862 |
22 |
0.996
|
Human |
|
|
negative regulation of steroid hormone biosynthetic process
|
GO:0090032 |
4 |
0.994
|
|
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
0.987
|
Human |
|
|
positive regulation of aldosterone biosynthetic process
|
GO:0032349 |
2 |
0.984
|
|
|
|
negative regulation of trophoblast cell migration
|
GO:1901164 |
3 |
0.971
|
Human |
|
|
regulation of cell proliferation involved in kidney development
|
GO:1901722 |
3 |
0.963
|
|
|
|
regulation of activin receptor signaling pathway
|
GO:0032925 |
14 |
0.963
|
Human |
|
|
negative regulation of glomerular mesangial cell proliferation
|
GO:0072125 |
2 |
0.956
|
|
|
|
regulation of aldosterone biosynthetic process
|
GO:0032347 |
6 |
0.947
|
|
|
|
regulation of glomerulus development
|
GO:0090192 |
3 |
0.927
|
|
|
|
positive regulation of biomineral tissue development
|
GO:0070169 |
20 |
0.916
|
|
|
|
positive regulation of hormone biosynthetic process
|
GO:0046886 |
4 |
0.916
|
|
|
|
positive regulation of steroid hormone biosynthetic process
|
GO:0090031 |
2 |
0.893
|
|
|
|
positive regulation of hyaluranon cable assembly
|
GO:1900106 |
3 |
0.860
|
|
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
38 |
0.857
|
Human |
|
|
regulation of smad protein import into nucleus
|
GO:0060390 |
10 |
0.843
|
Human |
|
|
negative regulation of chorionic trophoblast cell proliferation
|
GO:1901383 |
2 |
0.841
|
Human |
|
|
regulation of glomerular mesangial cell proliferation
|
GO:0072124 |
3 |
0.841
|
|
|
|
hyaluranon cable assembly
|
GO:0036118 |
3 |
0.834
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.813
|
|
|
|
positive regulation of bone mineralization
|
GO:0030501 |
19 |
0.758
|
|
|
|
aldosterone biosynthetic process
|
GO:0032342 |
9 |
0.753
|
|
|
|
cell proliferation involved in kidney development
|
GO:0072111 |
3 |
0.748
|
|
|
|
chorionic trophoblast cell proliferation
|
GO:0097360 |
2 |
0.733
|
Human |
|
|
mineralocorticoid metabolic process
|
GO:0008212 |
9 |
0.730
|
|
|
|
pattern specification involved in kidney development
|
GO:0061004 |
1 |
0.678
|
|
|
|
negative regulation of cortisol biosynthetic process
|
GO:2000065 |
4 |
0.672
|
|
|
|
diet induced thermogenesis
|
GO:0002024 |
2 |
0.669
|
|
|
|
type b pancreatic cell development
|
GO:0003323 |
4 |
0.651
|
|
|
|
regulation of hyaluranon cable assembly
|
GO:1900104 |
3 |
0.646
|
|
|
|
regulation of ketone biosynthetic process
|
GO:0010566 |
7 |
0.642
|
|
|
|
forelimb morphogenesis
|
GO:0035136 |
4 |
0.641
|
|
|
|
c21 steroid hormone biosynthetic process
|
GO:0006700 |
11 |
0.638
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.638
|
|
|
|
regulation of chorionic trophoblast cell proliferation
|
GO:1901382 |
2 |
0.631
|
Human |
|
|
regulation of bone mineralization
|
GO:0030500 |
29 |
0.625
|
|
|
|
regulation of cortisol biosynthetic process
|
GO:2000064 |
5 |
0.602
|
|
|
|
negative regulation of glucocorticoid metabolic process
|
GO:0031944 |
4 |
0.588
|
|
|
|
glomerular mesangial cell proliferation
|
GO:0072110 |
3 |
0.544
|
|
|
|
enteroendocrine cell differentiation
|
GO:0035883 |
6 |
0.543
|
|
|
|
positive regulation of sarcomere organization
|
GO:0060298 |
2 |
0.534
|
|
|
|
metanephros development
|
GO:0001656 |
16 |
0.533
|
|
|
|
bone mineralization
|
GO:0030282 |
34 |
0.531
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.516
|
|
|
|
regulation of biomineral tissue development
|
GO:0070167 |
31 |
0.505
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.502
|
|
|
|
hindlimb morphogenesis
|
GO:0035137 |
2 |
0.502
|
|
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
38 |
0.497
|
Human |
|
|
hormone metabolic process
|
GO:0042445 |
61 |
0.489
|
|
|
|
monocyte aggregation
|
GO:0070487 |
4 |
0.488
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.480
|
Fly |
|
|
negative regulation of insulin like growth factor receptor signaling pathway
|
GO:0043569 |
4 |
0.479
|
|
|
|
ketone biosynthetic process
|
GO:0042181 |
17 |
0.461
|
|
|
|
glucocorticoid metabolic process
|
GO:0008211 |
10 |
0.459
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.455
|
Human Fly |
|
|
regulation of aldosterone metabolic process
|
GO:0032344 |
6 |
0.450
|
|
|
|
mineralocorticoid biosynthetic process
|
GO:0006705 |
9 |
0.450
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.448
|
|
|
|
positive regulation of steroid biosynthetic process
|
GO:0010893 |
6 |
0.442
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.440
|
Human |
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.434
|
Fly |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.414
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.403
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.394
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.393
|
Human |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.389
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.388
|
Human |
|
|
glandular epithelial cell development
|
GO:0002068 |
5 |
0.388
|
|
|
|
biomineral tissue development
|
GO:0031214 |
39 |
0.383
|
|
|
|
mesonephros development
|
GO:0001823 |
17 |
0.377
|
|
|
|
smad protein import into nucleus
|
GO:0007184 |
13 |
0.376
|
Human |
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.374
|
Human |
|
|
positive regulation of smad protein import into nucleus
|
GO:0060391 |
8 |
0.369
|
Human |
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.366
|
Human |
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.366
|
Human |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.362
|
Human |
|
|
endoderm formation
|
GO:0001706 |
33 |
0.360
|
Fly |
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.358
|
Human |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.357
|
Human Fly |
|
|
cellular hormone metabolic process
|
GO:0034754 |
41 |
0.356
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.353
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.349
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.348
|
|
|
|
pancreas development
|
GO:0031016 |
19 |
0.345
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.340
|
|
|
|
patterning of blood vessels
|
GO:0001569 |
2 |
0.337
|
|
|
|
glomerulus development
|
GO:0032835 |
15 |
0.336
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.334
|
Human Fly |
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.333
|
Human |
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.333
|
Human |
|
|
system process
|
GO:0003008 |
349 |
0.333
|
Human |
|
|
tissue migration
|
GO:0090130 |
119 |
0.329
|
Human |
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.329
|
Human |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.322
|
Human |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.322
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.321
|
Human |
|
|
energy homeostasis
|
GO:0097009 |
3 |
0.318
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.313
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.312
|
Human |
|
|
glucocorticoid biosynthetic process
|
GO:0006704 |
8 |
0.311
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.311
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.310
|
Human |
|
|
endocrine pancreas development
|
GO:0031018 |
11 |
0.303
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.302
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.302
|
Human |
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.301
|
Human |
|
|
cardiac muscle hypertrophy
|
GO:0003300 |
14 |
0.301
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.298
|
Human |
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.296
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.292
|
|
|
|
positive regulation of striated muscle cell differentiation
|
GO:0051155 |
9 |
0.291
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.288
|
Human |
|
|
renal system pattern specification
|
GO:0072048 |
1 |
0.287
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.286
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.285
|
Human |
|
|
muscle contraction
|
GO:0006936 |
73 |
0.285
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.283
|
|
|
|
smad protein signal transduction
|
GO:0060395 |
10 |
0.280
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.280
|
Human |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.279
|
Human |
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
33 |
0.278
|
|
|
|
glandular epithelial cell differentiation
|
GO:0002067 |
6 |
0.276
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.271
|
Human |
|
|
regulation of multicellular organismal metabolic process
|
GO:0044246 |
17 |
0.271
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.271
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.269
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.266
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.266
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.265
|
Human |
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.263
|
Human |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.262
|
Human |
|
|
response to lipid
|
GO:0033993 |
206 |
0.259
|
Human |
|
|
epithelium migration
|
GO:0090132 |
119 |
0.258
|
Human |
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.258
|
Human |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.256
|
Human |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.256
|
Human |
|
|
regulation of sarcomere organization
|
GO:0060297 |
3 |
0.254
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.253
|
Human Fly |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.252
|
Human |
|
|
circulatory system process
|
GO:0003013 |
113 |
0.251
|
Human |
|
|
endoderm development
|
GO:0007492 |
33 |
0.249
|
Fly |
|
|
negative regulation of hormone metabolic process
|
GO:0032351 |
6 |
0.249
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.246
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.245
|
Fly |
|
|
regulation of steroid biosynthetic process
|
GO:0050810 |
23 |
0.245
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.245
|
Human |
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.244
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.241
|
Human |
|
|
connective tissue development
|
GO:0061448 |
39 |
0.241
|
Human Mouse |
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.237
|
Fly |
|
|
skeletal system development
|
GO:0001501 |
79 |
0.233
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.232
|
Human |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.232
|
Human Fly |
|
|
positive regulation of lipid biosynthetic process
|
GO:0046889 |
22 |
0.231
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.231
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.229
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.228
|
Human |
|
|
response to dietary excess
|
GO:0002021 |
2 |
0.227
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.226
|
Human |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.225
|
Human |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.224
|
Human |
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.224
|
Fly |
|
|
negative regulation of aldosterone biosynthetic process
|
GO:0032348 |
4 |
0.223
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.222
|
Human |
|
|
regulation of heterotypic cell cell adhesion
|
GO:0034114 |
14 |
0.221
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.221
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.221
|
Human Fly |
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.221
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.220
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.220
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.219
|
Human |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.218
|
Human |
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.218
|
Human |
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.217
|
Human |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.217
|
Human Fly |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.215
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.214
|
Human |
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.213
|
Human Fly |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.211
|
Fly |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.211
|
Human |
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.211
|
Human |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.209
|
Human |
|
|
positive regulation of multicellular organismal metabolic process
|
GO:0044253 |
11 |
0.209
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.208
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.205
|
Human Mouse Fly |
|
|
kidney development
|
GO:0001822 |
53 |
0.205
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.205
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.204
|
Human Fly |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.201
|
|
|
|
regulation of hormone metabolic process
|
GO:0032350 |
14 |
0.200
|
|
|
|
regulation of insulin like growth factor receptor signaling pathway
|
GO:0043567 |
8 |
0.200
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.200
|
Human |
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.198
|
Human |
|
|
digestive tract development
|
GO:0048565 |
75 |
0.198
|
Fly |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.193
|
Human Mouse Fly |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.193
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.192
|
Human Fly |
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.191
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.190
|
Human Mouse Fly |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.189
|
Human |
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
0.188
|
|
|
|
kidney vasculature development
|
GO:0061440 |
7 |
0.188
|
|
|
|
muscle adaptation
|
GO:0043500 |
12 |
0.187
|
|
|
|
multicellular organismal metabolic process
|
GO:0044236 |
34 |
0.186
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.186
|
Human |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.184
|
Human |
|
|
cytokine production
|
GO:0001816 |
247 |
0.184
|
|
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
15 |
0.182
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.181
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.180
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.178
|
|
|
|
endocrine system development
|
GO:0035270 |
26 |
0.177
|
|
|
|
regulation of muscle cell differentiation
|
GO:0051147 |
31 |
0.176
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.176
|
Human |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.174
|
Human |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.174
|
Human |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.174
|
Human Mouse |
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
37 |
0.173
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.173
|
Human |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.172
|
Human |
|
|
digestive system development
|
GO:0055123 |
75 |
0.171
|
Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.171
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.170
|
|
|
|
regulation of alcohol biosynthetic process
|
GO:1902930 |
22 |
0.170
|
|
|
|
regulation of energy homeostasis
|
GO:2000505 |
1 |
0.168
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.168
|
Human |
|
|
positive regulation of steroid metabolic process
|
GO:0045940 |
13 |
0.164
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.163
|
Human |
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.163
|
Human |
|
|
protein targeting
|
GO:0006605 |
187 |
0.161
|
Human |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.159
|
Human |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.159
|
Fly |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.159
|
Human Mouse |
|
|
regulation of muscle contraction
|
GO:0006937 |
45 |
0.158
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.158
|
Human |
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.158
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.155
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.155
|
Human |
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.154
|
Human |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.154
|
|
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
29 |
0.153
|
Human |
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.152
|
Human |
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.152
|
Human |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.152
|
Human |
|
|
hormone biosynthetic process
|
GO:0042446 |
22 |
0.151
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.149
|
Human |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.149
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.147
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.147
|
Human |
|
|
gastrulation
|
GO:0007369 |
51 |
0.146
|
Fly |
|
|
type b pancreatic cell differentiation
|
GO:0003309 |
5 |
0.145
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.144
|
Human Fly |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.144
|
Human |
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.143
|
Human |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.143
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.143
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.142
|
Human Mouse |
|
|
hormone secretion
|
GO:0046879 |
65 |
0.141
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.140
|
Human |
|
|
dna biosynthetic process
|
GO:0071897 |
40 |
0.140
|
Human |
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.140
|
Human |
|
|
regulation of striated muscle contraction
|
GO:0006942 |
37 |
0.139
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.139
|
Fly |
|
|
muscle hypertrophy
|
GO:0014896 |
14 |
0.138
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.137
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.137
|
Fly |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.137
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.136
|
Human |
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.136
|
Human |
|
|
nervous system development
|
GO:0007399 |
293 |
0.136
|
Mouse Fly |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.135
|
Human |
|
|
steroid hormone mediated signaling pathway
|
GO:0043401 |
12 |
0.135
|
|
|
|
positive regulation of organelle assembly
|
GO:1902117 |
17 |
0.134
|
|
|
|
glomerulus vasculature development
|
GO:0072012 |
6 |
0.132
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.131
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.130
|
Human |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.129
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.129
|
Mouse |
|
|
response to bmp
|
GO:0071772 |
8 |
0.129
|
Human |
|
|
steroid biosynthetic process
|
GO:0006694 |
46 |
0.129
|
|
|
|
growth
|
GO:0040007 |
202 |
0.128
|
Human Mouse Fly |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.128
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.128
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.127
|
Human Fly |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.125
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.125
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.125
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.124
|
Human Fly |
|
|
response to hormone
|
GO:0009725 |
175 |
0.123
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.123
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.122
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.122
|
|
|
|
regulation of hormone biosynthetic process
|
GO:0046885 |
10 |
0.120
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.120
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
25 |
0.119
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.119
|
Human |
|
|
peptide hormone secretion
|
GO:0030072 |
50 |
0.118
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.118
|
|
|
|
cellular response to bmp stimulus
|
GO:0071773 |
8 |
0.118
|
Human |
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.117
|
Human |
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.117
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.117
|
Human Fly |
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
36 |
0.117
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.116
|
Human |
|
|
positive regulation of heterotypic cell cell adhesion
|
GO:0034116 |
8 |
0.116
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.116
|
Fly |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.116
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.115
|
|
|
|
regulation of glucocorticoid metabolic process
|
GO:0031943 |
6 |
0.114
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.114
|
Human |
|
|
positive regulation of muscle hypertrophy
|
GO:0014742 |
6 |
0.113
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.113
|
|
|
|
mesenchymal to epithelial transition involved in metanephros morphogenesis
|
GO:0003337 |
4 |
0.112
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.112
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.112
|
Mouse |
|
|
hormone mediated signaling pathway
|
GO:0009755 |
22 |
0.112
|
|
|
|
cortisol metabolic process
|
GO:0034650 |
8 |
0.111
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.111
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.111
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.110
|
Human |
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
37 |
0.110
|
|
|
|
cartilage development
|
GO:0051216 |
31 |
0.110
|
Human Mouse |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.108
|
Human Fly |
|
|
organelle assembly
|
GO:0070925 |
176 |
0.107
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.107
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.107
|
|
|
|
regulation of cartilage development
|
GO:0061035 |
12 |
0.107
|
|
|
|
bmp signaling pathway involved in heart development
|
GO:0061312 |
3 |
0.107
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.106
|
Mouse |
|
|
heart contraction
|
GO:0060047 |
62 |
0.105
|
|
|
|
c21 steroid hormone metabolic process
|
GO:0008207 |
17 |
0.105
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.104
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.101
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.101
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.101
|
Human |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.101
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.101
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.100
|
Human |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.100
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.098
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.096
|
Human Fly |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.095
|
Human Mouse Fly |
|
|
heart process
|
GO:0003015 |
62 |
0.095
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.092
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.092
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.091
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.091
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.091
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.091
|
Fly |
|
|
peptide transport
|
GO:0015833 |
74 |
0.090
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.090
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.089
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.089
|
Mouse |
|
|
regulation of organelle assembly
|
GO:1902115 |
40 |
0.088
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.088
|
Fly |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.087
|
Human Fly |
|
|
nuclear division
|
GO:0000280 |
128 |
0.086
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.086
|
Fly |
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.085
|
|
|
|
regulation of steroid metabolic process
|
GO:0019218 |
32 |
0.084
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.084
|
|
|
|
nephron development
|
GO:0072006 |
30 |
0.084
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.084
|
|
|
|
peptide secretion
|
GO:0002790 |
51 |
0.084
|
|
|
|
leukocyte aggregation
|
GO:0070486 |
8 |
0.083
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.082
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.082
|
|
|
|
positive regulation of chondrocyte differentiation
|
GO:0032332 |
4 |
0.082
|
|
|
|
regulation of kidney development
|
GO:0090183 |
10 |
0.082
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.080
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.079
|
Fly |
|
|
negative regulation of aldosterone metabolic process
|
GO:0032345 |
4 |
0.079
|
|
|
|
negative regulation of peptide hormone secretion
|
GO:0090278 |
10 |
0.079
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.078
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.077
|
|
|
|
alcohol biosynthetic process
|
GO:0046165 |
52 |
0.077
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.076
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.076
|
|
|
|
positive regulation of odontogenesis
|
GO:0042482 |
3 |
0.075
|
|
|
|
negative regulation of steroid biosynthetic process
|
GO:0010894 |
15 |
0.075
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.075
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.073
|
Human |
|
|
positive regulation of hormone metabolic process
|
GO:0032352 |
6 |
0.073
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.073
|
|
|
|
columnar cuboidal epithelial cell development
|
GO:0002066 |
5 |
0.073
|
Fly |
|
|
organelle fission
|
GO:0048285 |
149 |
0.072
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.071
|
Mouse |
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.071
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.071
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.070
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.070
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.069
|
Mouse Fly |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.069
|
Mouse Fly |
|
|
regulation of muscle hypertrophy
|
GO:0014743 |
10 |
0.067
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
21 |
0.067
|
|
|
|
specification of organ identity
|
GO:0010092 |
3 |
0.067
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.066
|
|
|
|
vascular endothelial growth factor production
|
GO:0010573 |
15 |
0.065
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.065
|
Human |
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.065
|
|
|
|
negative regulation of cell division
|
GO:0051782 |
31 |
0.065
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.065
|
Human |
|
|
appendage development
|
GO:0048736 |
23 |
0.064
|
|
|
|
endodermal mesodermal cell signaling
|
GO:0003133 |
3 |
0.064
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.064
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.063
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.062
|
|
|
|
negative regulation of hormone secretion
|
GO:0046888 |
15 |
0.061
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.061
|
Human Fly |
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.060
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
17 |
0.060
|
Human Mouse |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.060
|
Human |
|
|
striated muscle hypertrophy
|
GO:0014897 |
14 |
0.060
|
|
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.060
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.059
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.058
|
Human |
|
|
forebrain regionalization
|
GO:0021871 |
3 |
0.058
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
14 |
0.058
|
Fly |
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.058
|
|
|
|
positive regulation of cell cell adhesion
|
GO:0022409 |
22 |
0.057
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.057
|
Human |
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
20 |
0.057
|
|
|
|
negative regulation of lipid biosynthetic process
|
GO:0051055 |
22 |
0.057
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
41 |
0.056
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.056
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.055
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.055
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.055
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.055
|
|
|
|
androgen receptor signaling pathway
|
GO:0030521 |
34 |
0.054
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.054
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.054
|
|
|
|
negative regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033144 |
18 |
0.054
|
|
|
|
pituitary gland development
|
GO:0021983 |
2 |
0.053
|
|
|
|
branch elongation involved in ureteric bud branching
|
GO:0060681 |
2 |
0.053
|
|
|
|
regulation of branching involved in ureteric bud morphogenesis
|
GO:0090189 |
3 |
0.053
|
|
|
|
regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033143 |
32 |
0.052
|
|
|
|
limb morphogenesis
|
GO:0035108 |
16 |
0.052
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.052
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.051
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.050
|
Fly |
|
|
negative regulation of insulin secretion
|
GO:0046676 |
9 |
0.050
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.049
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.049
|
Fly |
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.049
|
|
|
|
regulation of muscle adaptation
|
GO:0043502 |
10 |
0.049
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.049
|
Human |
|
|
oocyte development
|
GO:0048599 |
1 |
0.048
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.048
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
26 |
0.047
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
42 |
0.047
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.047
|
Fly |
|
|
positive regulation of cardiac muscle hypertrophy
|
GO:0010613 |
6 |
0.047
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.046
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.046
|
Human |
|
|
pattern specification process
|
GO:0007389 |
43 |
0.046
|
Human Mouse Fly |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.046
|
Human |
|
|
epithelial tube branching involved in lung morphogenesis
|
GO:0060441 |
4 |
0.046
|
|
|
|
regulation of insulin secretion
|
GO:0050796 |
33 |
0.046
|
|
|
|
negative regulation of mitosis
|
GO:0045839 |
24 |
0.046
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.046
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.045
|
Human |
|
|
insulin like growth factor receptor signaling pathway
|
GO:0048009 |
13 |
0.045
|
|
|
|
ureteric bud elongation
|
GO:0060677 |
2 |
0.044
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.044
|
Human |
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.044
|
Human |
|
|
positive regulation vascular endothelial growth factor production
|
GO:0010575 |
12 |
0.043
|
|
|
|
mesodermal cell fate commitment
|
GO:0001710 |
2 |
0.043
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
47 |
0.042
|
|
|
|
mesoderm development
|
GO:0007498 |
14 |
0.041
|
|
|
|
regulation of dna dependent dna replication
|
GO:0090329 |
19 |
0.041
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.040
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.040
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.040
|
Human |
|
|
heart formation
|
GO:0060914 |
2 |
0.040
|
|
|
|
ureter development
|
GO:0072189 |
3 |
0.040
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.039
|
Fly |
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.039
|
|
