Homo sapiens

175 known processes

BRCA2

breast cancer 2, early onset

(Aliases: FAD1,GLM3,PNCA2,BRCC2,FACD,FANCD,BROVCA2,FANCB,FAD,FANCD1)

BRCA2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
double strand break repair via homologous recombination GO:0000724 50 0.999
male meiosis GO:0007140 1 0.998
Mouse
cellular response to dna damage stimulus GO:0006974 379 0.997
double strand break repair GO:0006302 101 0.996
nuclear division GO:0000280 128 0.996
Mouse
dna repair GO:0006281 198 0.996
dna recombination GO:0006310 77 0.991
response to radiation GO:0009314 151 0.989
Mouse
regulation of double strand break repair via homologous recombination GO:0010569 11 0.989
recombinational repair GO:0000725 50 0.987
oocyte maturation GO:0001556 1 0.981
Mouse
response to caffeine GO:0031000 3 0.891
oocyte development GO:0048599 1 0.889
Mouse
regulation of cell cycle GO:0051726 393 0.888
Mouse
oocyte differentiation GO:0009994 2 0.865
Mouse
regulation of cell cycle phase transition GO:1901987 126 0.858
reciprocal meiotic recombination GO:0007131 4 0.850
spermatid development GO:0007286 4 0.849
reproductive process GO:0022414 106 0.847
Mouse
female gamete generation GO:0007292 2 0.847
Mouse
nucleoside monophosphate catabolic process GO:0009125 159 0.834
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.811
oogenesis GO:0048477 2 0.804
Mouse
mitotic cell cycle checkpoint GO:0007093 68 0.798
purine nucleoside catabolic process GO:0006152 398 0.790
meiotic chromosome segregation GO:0045132 4 0.780
response to ionizing radiation GO:0010212 65 0.778
Mouse
double strand break repair via single strand annealing GO:0045002 4 0.771
g2 m transition of mitotic cell cycle GO:0000086 41 0.756
cell cycle checkpoint GO:0000075 117 0.740
meiotic nuclear division GO:0007126 10 0.715
Mouse
reciprocal dna recombination GO:0035825 4 0.707
nucleoside phosphate catabolic process GO:1901292 412 0.699
purine ribonucleoside catabolic process GO:0046130 398 0.689
atp catabolic process GO:0006200 157 0.659
sister chromatid cohesion GO:0007062 24 0.635
regulation of mitotic cell cycle GO:0007346 189 0.629
Mouse
regulation of meiotic cell cycle GO:0051445 4 0.602
mitotic recombination GO:0006312 8 0.591
regulation of double strand break repair GO:2000779 22 0.588
cell division GO:0051301 168 0.564
cell development GO:0048468 328 0.553
Mouse
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.549
nucleoside triphosphate catabolic process GO:0009143 394 0.535
purine nucleotide catabolic process GO:0006195 405 0.530
ribonucleoside monophosphate catabolic process GO:0009158 158 0.525
chromosome segregation GO:0007059 114 0.457
dna integrity checkpoint GO:0031570 71 0.446
ribonucleotide catabolic process GO:0009261 405 0.432
anterior posterior axis specification GO:0009948 2 0.429
cellular response to abiotic stimulus GO:0071214 117 0.428
dna conformation change GO:0071103 113 0.401
positive regulation of mitotic cell cycle GO:0045931 60 0.398
Mouse
spermatid differentiation GO:0048515 4 0.379
dna dependent dna replication GO:0006261 44 0.377
Mouse
spindle checkpoint GO:0031577 26 0.363
non recombinational repair GO:0000726 14 0.362
regulation of kinase activity GO:0043549 314 0.360
mitotic cell cycle process GO:1903047 286 0.355
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.346
ubiquitin dependent protein catabolic process GO:0006511 206 0.346
organelle fission GO:0048285 149 0.342
Mouse
mitotic cell cycle phase transition GO:0044772 162 0.329
glycosyl compound catabolic process GO:1901658 413 0.319
regulation of dna metabolic process GO:0051052 153 0.314
Mouse
negative regulation of dna metabolic process GO:0051053 57 0.312
Mouse
strand invasion GO:0042148 2 0.307
cellular response to endogenous stimulus GO:0071495 336 0.301
ribonucleoside catabolic process GO:0042454 406 0.298
response to abiotic stimulus GO:0009628 336 0.298
Mouse
cytokinesis GO:0000910 96 0.294
single organism reproductive process GO:0044702 98 0.289
Mouse
ribonucleoside monophosphate metabolic process GO:0009161 187 0.280
meiotic cell cycle GO:0051321 13 0.278
Mouse
purine nucleoside monophosphate catabolic process GO:0009128 158 0.277
negative regulation of cell proliferation GO:0008285 228 0.259
regulation of dna repair GO:0006282 47 0.258
purine nucleoside triphosphate catabolic process GO:0009146 392 0.258
dna geometric change GO:0032392 32 0.255
sister chromatid segregation GO:0000819 54 0.255
dna replication GO:0006260 116 0.245
Mouse
nucleotide excision repair GO:0006289 31 0.239
purine nucleoside monophosphate metabolic process GO:0009126 186 0.226
regulation of transferase activity GO:0051338 355 0.214
negative regulation of chromosome segregation GO:0051985 18 0.210
centrosome organization GO:0051297 58 0.202
negative regulation of thymocyte apoptotic process GO:0070244 1 0.200
g2 dna damage checkpoint GO:0031572 26 0.200
negative regulation of cell cycle GO:0045786 193 0.195
dna unwinding involved in dna replication GO:0006268 2 0.193
multi organism reproductive process GO:0044703 54 0.189
Mouse
negative regulation of mitotic cell cycle GO:0045930 102 0.188
positive regulation of cell cycle process GO:0090068 106 0.188
purine ribonucleotide catabolic process GO:0009154 404 0.178
regulation of response to dna damage stimulus GO:2001020 94 0.175
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.170
nucleotide catabolic process GO:0009166 408 0.169
regulation of protein serine threonine kinase activity GO:0071900 179 0.169
mitotic sister chromatid segregation GO:0000070 53 0.166
negative regulation of cell cycle process GO:0010948 121 0.163
specification of axis polarity GO:0065001 1 0.162
regulation of protein kinase activity GO:0045859 289 0.161
purine ribonucleoside metabolic process GO:0046128 437 0.161
intracellular mrna localization GO:0008298 1 0.154
dna duplex unwinding GO:0032508 30 0.152
dna catabolic process GO:0006308 49 0.151
dna double strand break processing GO:0000729 10 0.150
nucleoside triphosphate metabolic process GO:0009141 422 0.146
protein maturation GO:0051604 233 0.142
chromosome separation GO:0051304 23 0.139
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.137
organophosphate catabolic process GO:0046434 430 0.134
mitotic nuclear division GO:0007067 119 0.130
developmental process involved in reproduction GO:0003006 66 0.130
Mouse
cellular macromolecule catabolic process GO:0044265 380 0.130
nucleoside monophosphate metabolic process GO:0009123 191 0.123
dna damage checkpoint GO:0000077 68 0.123
dna ligation GO:0006266 10 0.121
dna packaging GO:0006323 77 0.119
positive regulation of cell cycle GO:0045787 140 0.119
Mouse
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.119
regulation of dna replication GO:0006275 68 0.118
Mouse
negative regulation of cellular catabolic process GO:0031330 83 0.118
regulation of protein maturation GO:1903317 150 0.116
base excision repair GO:0006284 21 0.114
regulation of mitotic sister chromatid separation GO:0010965 27 0.114
spermatogenesis GO:0007283 22 0.113
Mouse
double strand break repair via nonhomologous end joining GO:0006303 10 0.112
positive regulation of hydrolase activity GO:0051345 331 0.110
regulation of cell division GO:0051302 116 0.110
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 412 0.109
microtubule cytoskeleton organization GO:0000226 176 0.109
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.108
regulation of proteasomal protein catabolic process GO:0061136 87 0.105
nucleoside catabolic process GO:0009164 408 0.105
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.104
positive regulation of protein phosphorylation GO:0001934 313 0.104
negative regulation of cellular protein metabolic process GO:0032269 353 0.103
purine nucleoside triphosphate metabolic process GO:0009144 412 0.102
multicellular organism reproduction GO:0032504 42 0.102
Mouse
negative regulation of chromosome organization GO:2001251 48 0.102
meiosis i GO:0007127 4 0.102
Mouse
cellular response to oxygen containing compound GO:1901701 276 0.101
negative regulation of mitotic sister chromatid separation GO:2000816 17 0.100
regulation of cellular response to stress GO:0080135 244 0.099
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.098
negative regulation of protein metabolic process GO:0051248 391 0.098
positive regulation of apoptotic process GO:0043065 246 0.096
nervous system development GO:0007399 293 0.094
Mouse
post embryonic development GO:0009791 2 0.093
determination of adult lifespan GO:0008340 2 0.093
negative regulation of sister chromatid segregation GO:0033046 17 0.092
negative regulation of cell death GO:0060548 345 0.090
negative regulation of cellular protein catabolic process GO:1903363 38 0.089
negative regulation of protein processing GO:0010955 142 0.085
response to inorganic substance GO:0010035 127 0.084
multicellular organismal reproductive process GO:0048609 40 0.083
Mouse
cellular response to alkaloid GO:0071312 11 0.081
atp metabolic process GO:0046034 176 0.081
negative regulation of organelle organization GO:0010639 126 0.079
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.078
Mouse
rna localization GO:0006403 41 0.078
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.077
dna damage induced protein phosphorylation GO:0006975 5 0.075
cellular response to ionizing radiation GO:0071479 32 0.074
dna biosynthetic process GO:0071897 40 0.073
positive regulation of cellular amine metabolic process GO:0033240 7 0.071
microtubule based process GO:0007017 210 0.070
cellular process involved in reproduction in multicellular organism GO:0022412 15 0.068
Mouse
negative regulation of multicellular organismal process GO:0051241 317 0.068
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.068
mitotic cell cycle GO:0000278 326 0.068
Mouse
male gamete generation GO:0048232 22 0.067
Mouse
negative regulation of developmental process GO:0051093 247 0.067
developmental maturation GO:0021700 28 0.065
Mouse
regulation of mitotic sister chromatid segregation GO:0033047 27 0.065
response to uv GO:0009411 73 0.063
Mouse
anatomical structure homeostasis GO:0060249 100 0.063
negative regulation of mitosis GO:0045839 24 0.061
positive regulation of meiotic cell cycle GO:0051446 2 0.060
regulation of sister chromatid segregation GO:0033045 27 0.059
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 17 0.059
negative regulation of cell division GO:0051782 31 0.058
response to light stimulus GO:0009416 87 0.058
Mouse
mitotic dna damage checkpoint GO:0044773 28 0.057
metaphase anaphase transition of cell cycle GO:0044784 21 0.057
signal transduction by phosphorylation GO:0023014 297 0.056
reproduction GO:0000003 63 0.055
Mouse
immune system development GO:0002520 195 0.055
Mouse
cell cycle phase transition GO:0044770 173 0.054
regulation of mitotic cell cycle phase transition GO:1901990 118 0.054
nucleosome organization GO:0034728 66 0.054
dna catabolic process endonucleolytic GO:0000737 37 0.054
regulation of centrosome cycle GO:0046605 15 0.053
negative regulation of protein modification process GO:0031400 200 0.051
positive regulation of cellular component organization GO:0051130 376 0.050
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.049
response to transition metal nanoparticle GO:1990267 29 0.049
telomere maintenance via recombination GO:0000722 4 0.049
intrinsic apoptotic signaling pathway GO:0097193 127 0.049
Mouse
protein modification by small protein conjugation GO:0032446 342 0.047
positive regulation of phosphorylation GO:0042327 394 0.046
mitotic spindle checkpoint GO:0071174 18 0.045
positive regulation of kinase activity GO:0033674 204 0.044
sexual reproduction GO:0019953 37 0.044
Mouse
regulation of protein ubiquitination GO:0031396 95 0.044
negative regulation of apoptotic process GO:0043066 316 0.044
regulation of cellular amino acid metabolic process GO:0006521 6 0.044
negative regulation of protein phosphorylation GO:0001933 140 0.043
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.043
regulation of cellular ketone metabolic process GO:0010565 50 0.043
regulation of protein processing GO:0070613 150 0.043
negative regulation of cellular component organization GO:0051129 235 0.042
chromatin remodeling GO:0006338 55 0.042
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.041
positive regulation of programmed cell death GO:0043068 249 0.041
hemopoiesis GO:0030097 180 0.040
Mouse
regulation of cell cycle process GO:0010564 266 0.040
Mouse
regulation of protein catabolic process GO:0042176 155 0.040
negative regulation of catalytic activity GO:0043086 335 0.040
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.040
regulation of endopeptidase activity GO:0052548 170 0.039
cellular response to radiation GO:0071478 65 0.039
negative regulation of phosphate metabolic process GO:0045936 267 0.039
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.038
telomere organization GO:0032200 33 0.037
positive regulation of catabolic process GO:0009896 310 0.037
response to organic cyclic compound GO:0014070 204 0.037
negative regulation of cell size GO:0045792 3 0.036
cytokine production GO:0001816 247 0.036
purine containing compound catabolic process GO:0072523 411 0.036
regulation of proteolysis GO:0030162 293 0.035
gamete generation GO:0007276 25 0.035
Mouse
regulation of protein localization GO:0032880 296 0.035
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:0042771 23 0.034
Mouse
response to alkaloid GO:0043279 20 0.034
regulation of vasculature development GO:1901342 97 0.034
negative regulation of phosphorus metabolic process GO:0010563 267 0.034
regulation of peptidase activity GO:0052547 180 0.033
small gtpase mediated signal transduction GO:0007264 78 0.033
response to organonitrogen compound GO:0010243 156 0.033
somatic diversification of immunoglobulins involved in immune response GO:0002208 3 0.033
response to metal ion GO:0010038 84 0.032
mitotic dna integrity checkpoint GO:0044774 30 0.032
protein oligomerization GO:0051259 173 0.031
negative regulation of phosphorylation GO:0042326 174 0.031
negative regulation of protein maturation GO:1903318 142 0.031
negative regulation of mitotic sister chromatid segregation GO:0033048 17 0.031
cellular response to organic cyclic compound GO:0071407 127 0.031
regulation of cellular amine metabolic process GO:0033238 11 0.031
regulation of dna dependent dna replication GO:0090329 19 0.031
Mouse
negative regulation of programmed cell death GO:0043069 321 0.030
regulation of growth GO:0040008 165 0.030
negative regulation of cell cycle phase transition GO:1901988 89 0.030
regulation of nucleotide catabolic process GO:0030811 205 0.030
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 30 0.030
regulation of sister chromatid cohesion GO:0007063 9 0.029
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.029
female gonad development GO:0008585 10 0.029
Mouse
growth GO:0040007 202 0.029
Mouse
positive regulation of developmental process GO:0051094 314 0.029
mitotic sister chromatid separation GO:0051306 18 0.029
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.029
meiotic cell cycle process GO:1903046 8 0.029
Mouse
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.028
negative regulation of histone h3 k9 methylation GO:0051573 3 0.028
regulation of cell cycle checkpoint GO:1901976 21 0.028
mitotic sister chromatid cohesion GO:0007064 12 0.027
development of primary female sexual characteristics GO:0046545 10 0.027
Mouse
protein ubiquitination GO:0016567 314 0.026
signal transduction in response to dna damage GO:0042770 57 0.026
Mouse
regulation of centrosome duplication GO:0010824 14 0.025
positive regulation of proteolysis GO:0045862 142 0.025
atp dependent chromatin remodeling GO:0043044 25 0.025
cell cycle g1 s phase transition GO:0044843 80 0.025
ras protein signal transduction GO:0007265 73 0.025
protein homooligomerization GO:0051260 100 0.025
positive regulation of intracellular transport GO:0032388 104 0.025
telomere maintenance GO:0000723 32 0.024
germ cell development GO:0007281 8 0.024
Mouse
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.024
membrane organization GO:0061024 292 0.024
amine metabolic process GO:0009308 44 0.024
positive regulation of cell death GO:0010942 263 0.023
epithelium development GO:0060429 227 0.023
cohesin localization to chromatin GO:0071921 4 0.023
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.023
apoptotic signaling pathway GO:0097190 268 0.023
Mouse
cellular response to external stimulus GO:0071496 111 0.022
histone modification GO:0016570 251 0.022
cellular response to nitrogen compound GO:1901699 144 0.022
negative regulation of protein catabolic process GO:0042177 59 0.022
generation of neurons GO:0048699 152 0.022
ribonucleoside triphosphate catabolic process GO:0009203 391 0.022
negative regulation of kinase activity GO:0033673 106 0.022
cellular response to organonitrogen compound GO:0071417 124 0.022
mapk cascade GO:0000165 288 0.022
metaphase plate congression GO:0051310 18 0.021
proteasomal protein catabolic process GO:0010498 176 0.021
negative regulation of cell differentiation GO:0045596 171 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.021
intra s dna damage checkpoint GO:0031573 4 0.021
regulation of protein stability GO:0031647 87 0.021
cellular protein catabolic process GO:0044257 261 0.021
regeneration GO:0031099 4 0.021
regulation of cellular protein catabolic process GO:1903362 96 0.021
negative regulation of proteolysis GO:0045861 132 0.020
negative regulation of cellular amine metabolic process GO:0033239 3 0.020
positive regulation of cell division GO:0051781 59 0.020
cellular ketone metabolic process GO:0042180 80 0.020
negative regulation of hydrolase activity GO:0051346 182 0.020
regulation of cytokine production GO:0001817 232 0.020
multi multicellular organism process GO:0044706 18 0.020
regulation of microtubule cytoskeleton organization GO:0070507 61 0.019
response to oxygen containing compound GO:1901700 369 0.019
cell cycle arrest GO:0007050 71 0.019
negative regulation of dna replication GO:0008156 29 0.019
Mouse
regulation of purine nucleotide catabolic process GO:0033121 205 0.019
cell type specific apoptotic process GO:0097285 125 0.019
regulation of binding GO:0051098 111 0.018
positive regulation of protein kinase activity GO:0045860 190 0.018
regulation of chromosome segregation GO:0051983 44 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.018
negative regulation of catabolic process GO:0009895 104 0.018
positive regulation of dna replication GO:0045740 35 0.018
positive regulation of cell differentiation GO:0045597 211 0.018
hindbrain development GO:0030902 3 0.018
mitotic g1 dna damage checkpoint GO:0031571 17 0.018
rna catabolic process GO:0006401 71 0.018
chemical homeostasis GO:0048878 306 0.018
response to transforming growth factor beta GO:0071559 94 0.017
pattern specification process GO:0007389 43 0.017
cation homeostasis GO:0055080 189 0.017
actin cytoskeleton organization GO:0030036 207 0.017
positive regulation of cell cycle phase transition GO:1901989 22 0.017
cellular amino acid metabolic process GO:0006520 116 0.016
regulation of cell differentiation GO:0045595 393 0.016
monocarboxylic acid biosynthetic process GO:0072330 67 0.016
positive regulation of protein ubiquitination GO:0031398 53 0.016
protein localization to organelle GO:0033365 280 0.016
leukocyte differentiation GO:0002521 98 0.016
mrna metabolic process GO:0016071 175 0.016
regulation of viral process GO:0050792 103 0.016
regulation of nuclear division GO:0051783 65 0.016
regulation of mitosis GO:0007088 63 0.016
regulation of establishment of protein localization GO:0070201 242 0.016
negative regulation of protein kinase activity GO:0006469 98 0.016
neuroblast proliferation GO:0007405 4 0.016
ovulation cycle process GO:0022602 9 0.015
segmentation GO:0035282 4 0.015
meiotic chromosome separation GO:0051307 3 0.015
g1 s transition of mitotic cell cycle GO:0000082 78 0.015
regulation of gene expression epigenetic GO:0040029 73 0.015
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.015
Mouse
i kappab kinase nf kappab signaling GO:0007249 166 0.015
protein deubiquitination GO:0016579 79 0.015
positive regulation of cellular catabolic process GO:0031331 284 0.015
cellular response to hormone stimulus GO:0032870 125 0.015
positive regulation of chromosome organization GO:2001252 41 0.015
response to gamma radiation GO:0010332 14 0.014
Mouse
positive regulation of chromosome segregation GO:0051984 9 0.014
protein processing GO:0016485 226 0.014
positive regulation of nucleotide metabolic process GO:0045981 230 0.014
synaptic transmission cholinergic GO:0007271 2 0.014
negative regulation of reactive oxygen species metabolic process GO:2000378 11 0.014
single organism cellular localization GO:1902580 332 0.014
rhythmic process GO:0048511 31 0.014
gonad development GO:0008406 34 0.014
Mouse
fatty acid biosynthetic process GO:0006633 46 0.014
regulation of cysteine type endopeptidase activity GO:2000116 127 0.014
cellular response to inorganic substance GO:0071241 45 0.013
regulation of purine nucleotide metabolic process GO:1900542 264 0.013
lymphocyte proliferation GO:0046651 70 0.013
cellular amine metabolic process GO:0044106 41 0.013
regionalization GO:0003002 29 0.013
regulation of g2 m transition of mitotic cell cycle GO:0010389 20 0.013
hematopoietic or lymphoid organ development GO:0048534 186 0.013
Mouse
posttranscriptional regulation of gene expression GO:0010608 213 0.013
regulation of cell development GO:0060284 161 0.013
lipid metabolic process GO:0006629 381 0.013
regulation of neural precursor cell proliferation GO:2000177 4 0.013
rna interference GO:0016246 4 0.013
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.013
Mouse
cell morphogenesis GO:0000902 296 0.013
negative regulation of peptidyl lysine acetylation GO:2000757 8 0.013
female sex differentiation GO:0046660 12 0.013
Mouse
regulation of gtpase activity GO:0043087 180 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.012
response to nitrogen compound GO:1901698 184 0.012
regulation of chromosome organization GO:0033044 103 0.012
regulation of mapk cascade GO:0043408 262 0.012
mitotic spindle assembly checkpoint GO:0007094 14 0.012
positive regulation of gtp catabolic process GO:0033126 166 0.012
chromosome condensation GO:0030261 15 0.012
spindle assembly checkpoint GO:0071173 17 0.012
negative regulation of cyclin dependent protein serine threonine kinase activity GO:0045736 15 0.012
receptor mediated endocytosis GO:0006898 84 0.012
thymocyte apoptotic process GO:0070242 2 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.012
positive regulation of peptidase activity GO:0010952 88 0.012
regulation of nervous system development GO:0051960 88 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
positive regulation of nuclear division GO:0051785 27 0.012
endocytosis GO:0006897 159 0.011
cell maturation GO:0048469 11 0.011
Mouse
positive regulation of cytoplasmic transport GO:1903651 82 0.011
positive regulation of mitotic cell cycle phase transition GO:1901992 19 0.011
regulation of non canonical wnt signaling pathway GO:2000050 4 0.011
positive regulation of cellular protein catabolic process GO:1903364 37 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.011
protein catabolic process GO:0030163 325 0.011
peptidyl lysine acetylation GO:0018394 101 0.011
neural tube closure GO:0001843 3 0.011
positive regulation of endopeptidase activity GO:0010950 84 0.011
cellular lipid metabolic process GO:0044255 303 0.011
intestinal absorption GO:0050892 4 0.011
response to drug GO:0042493 81 0.010
histone exchange GO:0043486 3 0.010
dna synthesis involved in dna repair GO:0000731 6 0.010
positive regulation of cell proliferation GO:0008284 301 0.010
positive regulation of protein transport GO:0051222 135 0.010
calcium ion homeostasis GO:0055074 122 0.010
positive regulation of growth GO:0045927 58 0.010
regulation of leukocyte activation GO:0002694 115 0.010
organelle assembly GO:0070925 176 0.010
carboxylic acid biosynthetic process GO:0046394 97 0.010
nuclear migration GO:0007097 1 0.010
replication fork processing GO:0031297 13 0.010

BRCA2 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 1.000
aplastic anemia DOID:12449 30 1.000
bone marrow disease DOID:4961 31 1.000
anemia DOID:2355 55 1.000
hematopoietic system disease DOID:74 100 1.000
congenital hypoplastic anemia DOID:1342 26 0.986
fanconi s anemia DOID:13636 16 0.986
thoracic cancer DOID:5093 21 0.973
cancer DOID:162 167 0.973
disease of cellular proliferation DOID:14566 174 0.973
organ system cancer DOID:0050686 164 0.973
endocrine gland cancer DOID:170 26 0.948
breast cancer DOID:1612 21 0.920
pancreatic cancer DOID:1793 8 0.690
musculoskeletal system cancer DOID:0060100 11 0.024
connective tissue cancer DOID:201 7 0.024
reproductive organ cancer DOID:193 23 0.007
nervous system cancer DOID:3093 12 0.001
urinary system cancer DOID:3996 15 0.001
central nervous system cancer DOID:3620 9 0.001
kidney cancer DOID:263 11 0.001
brain cancer DOID:1319 4 0.000
infratentorial cancer DOID:4706 3 0.000
medulloblastoma DOID:0050902 3 0.000
nephroblastoma DOID:2154 3 0.000
male reproductive organ cancer DOID:3856 16 0.000
prostate cancer DOID:10283 13 0.000